A biological tissue staining machine

By introducing a liquid absorption and dehumidification structure and a moving mechanism into the biological tissue staining machine, the problem of liquid accumulation caused by staining solution dripping is solved, and effective adsorption and cleaning of aqueous and organic liquids are achieved, thereby improving staining accuracy and equipment lifespan.

CN121113644BActive Publication Date: 2026-02-10NANJING ADVANCED ACAD OF LIFE & HEALTH
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Patent Information

Application Number
CN202511659565.5
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-11-13
Publication Date
2026-02-10
Estimated Expiration
2045-11-13

AI Technical Summary

Technical Problem

Existing biological tissue staining machines are prone to staining solution dripping during the staining process, leading to liquid accumulation, which affects reagent stability and equipment lifespan. Furthermore, traditional liquid suction components cannot effectively adsorb water and organic liquids, resulting in decreased staining accuracy.

Method used

A biological tissue staining machine was designed, which adopts a liquid absorption and dehumidification structure and a moving mechanism, including a liquid absorption belt, a fiber array of hairs and an air knife. By alternating the use of the liquid absorption belt and the cleaning of the air knife, effective adsorption and cleaning of aqueous and organic liquids can be achieved, preventing the formation of liquid accumulation.

Benefits of technology

It effectively prevents staining solution from dripping, reduces reagent waste and equipment corrosion, improves the accuracy of staining results and equipment lifespan, and enhances automation efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present application relates to a kind of biological tissue staining machines, including main component, moving mechanism and liquid suction dehumidification structure, main component includes shell, work tank, installation groove, mounting bracket and bearing frame, the top of shell is equipped with work tank, the bottom of work tank is equipped with installation groove. By setting up liquid suction dehumidification structure, can be actively connected the dyeing liquid, dehydrating agent dropped in dyeing process, avoid the formation of effusion in the bottom of work tank, reduce reagent waste from the source;Prevent the abnormal humidity in tank caused by effusion volatilization simultaneously, guarantee the reagent concentration stability of subsequent dyeing step, and avoid effusion corrosion equipment components, pollute the tissue to be dyed, significantly improve the accuracy of dyeing result.
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Description

Technical Field

[0001] This invention belongs to the field of biological tissue staining, specifically a biological tissue staining machine. Background Technology

[0002] In biomedical research and clinical pathological diagnosis, biological tissue staining is a key preliminary technique. It requires multiple steps such as tissue section fixation, dehydration, and staining using a staining machine, which involves the alternation and mixing of aqueous and organic liquids.

[0003] Existing staining machines have significant technical shortcomings: during the staining process, the staining solution easily drips into the staining machine as the slide moves, forming liquid accumulation in the working tank. This not only wastes reagents and increases humidity in the tank, affecting reagent stability, but may also corrode equipment, contaminate tissues, and reduce staining accuracy. Traditional liquid aspiration components are difficult to effectively adsorb both liquids due to the differences in surface tension and wettability between aqueous and organic liquids. These components are usually fixed and cannot be automatically and dynamically replaced or reused. If these liquid aspiration components are placed in the staining machine, the machine needs to be stopped and cleaned after they become saturated, reducing automation efficiency. Therefore, a biological tissue staining machine is proposed. Summary of the Invention

[0004] The purpose of this section is to outline some aspects of embodiments of the present invention and to briefly describe some preferred embodiments. Simplifications or omissions may be made in this section, as well as in the abstract and title of this application, to avoid obscuring the purpose of these documents; however, such simplifications or omissions should not be construed as limiting the scope of the invention.

[0005] Given the following technical problems in existing technologies: Most staining machines lack an effective liquid absorption mechanism: Most existing biological tissue staining machines are not designed with liquid absorption structures to address the dripping of staining solutions and dehydrating agents during the staining process, resulting in liquid dripping directly to the bottom of the working tank and forming accumulation, which in turn leads to problems such as reagent waste, abnormal humidity in the tank, corrosion of equipment components, and contamination of the tissue to be stained, affecting the accuracy of staining results. A few devices with liquid absorption functions use a single absorbent cotton, which has poor adaptability: Although some staining machines are equipped with liquid absorption components, they only use absorbent cotton of a single material; due to the significant differences in surface tension and wettability between aqueous and organic liquids, a single absorbent cotton cannot meet the adsorption needs of both liquids—it is insufficient for adsorption of aqueous liquids and easily penetrates too quickly and is difficult to stably bind organic liquids, ultimately still resulting in incomplete liquid absorption and the unresolved problem of liquid accumulation.

[0006] To solve the above-mentioned technical problems, the present invention provides the following technical solution: a biological tissue staining machine, comprising a main body component, a moving mechanism, and a liquid absorption and dehumidification structure. The main body component includes a shell, a working tank, a mounting tank, a mounting frame, and a load-bearing frame. The top of the shell has a working tank, and the bottom of the working tank has a mounting tank. Four load-bearing frames are arranged on the inner wall of the mounting tank, and a mounting frame is installed on the top of the mounting tank. The load-bearing frames support the mounting frame. The four load-bearing frames are evenly distributed on the inner wall of the mounting tank, which can distribute the weight of the mounting frame to different positions in the mounting tank, avoid deformation of the mounting frame due to concentrated force, and ensure the stable support of the mounting frame for the tissue bearing structure.

[0007] The bottom of the mounting tank is equipped with a liquid absorption and dehumidification structure. This structure is located at the bottom of the mounting tank and can directly catch liquid dripping from the mounting frame, preventing liquid from accumulating at the bottom of the mounting tank, reducing liquid erosion of the inner wall of the mounting tank, and extending the service life of the equipment.

[0008] A moving mechanism is provided on each side of the bottom of the working trough; the moving mechanisms are symmetrically arranged on both sides of the working trough, which can drive the material transfer operation synchronously from both sides, so that the structure supporting the organization is balanced in force during the movement, avoids the offset caused by unilateral drive, and ensures the accuracy of the material transfer position.

[0009] As a preferred technical solution for a biological tissue staining machine, a horizontal groove is provided on the back of the mounting slot, and the horizontal groove is slidably connected to the moving mechanism; the horizontal groove provides a fixed sliding path for the moving mechanism, which can limit the moving direction of the moving mechanism, prevent the moving mechanism from shifting laterally during the movement, and ensure that the moving mechanism always moves along the preset trajectory.

[0010] As a preferred technical solution for a biological tissue staining machine, the moving mechanism includes a moving stage and a moving arm. The moving arm is provided at one end of the moving stage, which extends into the horizontal groove and is slidably connected to the horizontal groove. The moving arm is above the mounting frame and is equipped with a transfer component. The sliding cooperation between the moving stage and the horizontal groove can drive the moving arm and the transfer component to move stably. Moreover, the moving arm is located above the mounting frame, so that the transfer component can accurately correspond to the tissue on the mounting frame and avoid misalignment during transfer.

[0011] As a preferred technical solution for a biological tissue staining machine, the transfer assembly includes a second moving stage, a connecting frame, a first connecting plate, and hooks. The second moving stage is movably connected to the moving arm. The first connecting plate is slidably connected to one side of the second moving stage. A matching hole is opened at the bottom of the second moving stage, which is movably connected to the moving arm. A vertical groove is opened on one side of the second moving stage. A connecting frame is set at the top of one side of the first connecting plate. The top of the connecting frame extends into the vertical groove. A linear motor is set inside the vertical groove. The movable end of the linear motor is connected to one end of the connecting frame. Two hooks are set at the bottom of the first connecting plate. The second moving stage is movably connected to the moving arm through the matching hole, which allows the second moving stage to be adjusted along the moving arm. The linear motor drives the connecting frame to move along the vertical groove, which can drive the first connecting plate and hooks to move up and down.

[0012] As a preferred technical solution for a biological tissue staining machine, the moving mechanism also includes a limiting frame. A limiting frame is fixedly installed on one side of the moving stage two. The limiting frame is L-shaped and is movably connected to one side of the moving stage two. The L-shaped limiting frame can block and limit the components on the outside of the moving stage two, preventing the components on the outside from shifting or falling off due to vibration when the moving stage two is moved or adjusted, thus ensuring the overall structural stability of the transfer assembly.

[0013] As a preferred technical solution for a biological tissue staining machine, the moving mechanism also includes a second connecting plate, a movable sleeve, and a first lead screw. The second connecting plate is located on the inner side of the second moving stage. A transverse groove is opened on one side of the moving arm, and a circular groove is opened inside the moving arm, which is connected to the transverse groove. The movable sleeve is movably connected inside the circular groove. The second connecting plate extends from the transverse groove into the circular groove and is fixedly connected to the movable sleeve. The first lead screw is rotatably connected to the center of the circular groove, and a servo motor is installed at one end of the circular groove. The power output end of the servo motor is fixedly connected to the first lead screw. The servo motor drives the first lead screw to rotate, which can drive the movable sleeve to move precisely along the circular groove. In turn, the second connecting plate drives the second moving stage to adjust its position along the transverse groove. The high precision characteristics of the lead screw drive can ensure the position adjustment accuracy of the second moving stage and meet the requirements of fine material transfer.

[0014] As a preferred technical solution for a biological tissue staining machine, the liquid absorption and dehumidification structure includes an absorption belt, a fiber array, and belt timing pulleys. Several belt timing pulleys are rotatably connected to the bottom of the mounting groove. The belt timing pulleys form a circle, with the absorption belt wrapped around its outer side. The inner side of the absorption belt is provided with connecting teeth that mesh with the outer side of the belt timing pulleys. The absorption belt has two absorption sections. The belt timing pulleys mesh with the teeth of the absorption belt to prevent belt slippage, ensure stable rotation of the absorption belt, and enable the alternating use of the two absorption sections. This avoids the need to stop and replace the machine after a single absorption section becomes saturated, thus improving the continuity of liquid absorption.

[0015] As a preferred technical solution for a biological tissue staining machine, the liquid absorption and dehumidification structure also includes an air knife, a sealing arc strip, a horn hole, an air intake channel, and a closed frame. Cleaning liquid nozzles are distributed on both sides of the air knife. The distance between the air knife and the liquid absorption belt is less than one millimeter. A closed frame is installed in the middle of the mounting groove. The two sides of the closed frame are fixedly connected to one side of the inner wall of the mounting groove. The closed frame is U-shaped, and a sealing arc strip is installed at the top of each end of the closed frame. The sealing arc strip is movably connected to the outer side of the belt synchronous pulley, and the sealing arc strip is pressed against the belt synchronous pulley. The liquid absorption part includes a liquid collection hole, a horn hole, and a fiber array. The absorbent section has a connecting section at each end, and an elastic sealing plate is provided on the outside of the connecting section. The outer side of the elastic sealing plate protrudes from the outer side of the absorbent belt. The absorbent section of the absorbent belt has several evenly distributed liquid collection holes, and the inner wall of the liquid collection holes has several evenly distributed horn holes. The inner wall of the liquid collection holes is provided with fiber array hairs. The absorbent section of the absorbent belt is located directly below or above the mounting frame. The distance between the air knife and the absorbent belt is less than one millimeter, which can ensure that the airflow sprayed by the air knife acts precisely on the fiber array hairs, accelerates liquid separation, and the cleaning liquid nozzle can directly spray cleaning liquid onto the fiber array hairs, improving cleaning efficiency.

[0016] The U-shaped enclosure, combined with the sealing arc strip and belt synchronous pulley, squeezes and seals to prevent liquid or airflow from overflowing from the liquid absorption area; the liquid collection hole can collect dripping liquid, the horn hole can expand the range of airflow or cleaning fluid, the fiber array can enhance the liquid absorption capacity, and the elastic sealing plate protrudes from the liquid absorption belt, which can fit against the inner wall of the installation groove when the liquid absorption part moves, reducing leakage from gaps.

[0017] An auxiliary groove is provided at each end of the bottom of the installation groove. The auxiliary groove is trapezoidal in shape and is equipped with a belt pulley. The inclined inner wall of the trapezoidal auxiliary groove can guide the connecting section, making it easy for the connecting section to be inserted or removed smoothly. The belt pulley in the groove can assist the liquid suction belt to rotate and reduce the friction loss of the edge of the liquid suction belt.

[0018] As a preferred technical solution for a biological tissue staining machine, the main components also include mating grooves and auxiliary mounting seats. Several mating grooves are evenly arranged on the mounting frame, and two auxiliary mounting seats are provided at both ends of the inner wall of the mating groove. Multiple mating grooves can realize the simultaneous installation of multiple sets of tissue support structures, thereby improving the staining efficiency of the equipment. The two auxiliary mounting seats on the inner wall of the mating groove can position and support the tissue support structure, preventing the tissue support structure from shifting due to vibration during the staining process.

[0019] As a preferred technical solution for a biological tissue staining machine, the liquid absorption and dehumidification structure also includes an arc-shaped cover and a liquid-repellent layer. A recovery platform is provided on one side of the mounting groove. The recovery platform is located at the opening of the auxiliary groove. The recovery platform is triangular prism-shaped. The end of the recovery platform away from the inner wall of the mounting groove is rounded. An arc-shaped cover is provided at one end of the liquid collection hole. The bottom of the recovery platform is movably connected to the elastic sealing plate and the arc-shaped cover. A liquid-repellent layer is provided on one side of the arc-shaped cover. The shape of the arc-shaped cover is three-quarters of a circle.

[0020] The beneficial effects of the biological tissue staining machine of the present invention are as follows: by setting up a liquid absorption and dehumidification structure, it can actively receive the staining solution and dehydrating agent dripping during the staining process, avoid the formation of liquid accumulation at the bottom of the working tank, and reduce reagent waste from the source; at the same time, it prevents abnormal humidity in the tank caused by the evaporation of accumulated liquid, ensures the stability of reagent concentration in subsequent staining steps, and avoids the accumulation of liquid from corroding equipment parts and contaminating the tissue to be stained, thus significantly improving the accuracy of staining results.

[0021] Using a blend of type A and type B fiber arrays as the core absorbent component, type A fibers can efficiently absorb water, while type B fibers can stably bind organic liquids. This perfectly adapts to the differences in surface tension and wettability between the two types of liquids, solving the problem of "insufficient absorption of water and easy penetration of organic liquids" with single absorbent cotton. It achieves complete absorption of both types of liquids and significantly reduces the risk of liquid accumulation. Attached Figure Description

[0022] To more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the following description of the embodiments will be briefly introduced. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Wherein:

[0023] Figure 1 This is a schematic diagram of the overall structure of the present invention;

[0024] Figure 2 This is a cross-sectional view of the front of the present invention;

[0025] Figure 3 This is a schematic diagram of the liquid absorption and dehumidification structure of the present invention;

[0026] Figure 4 For the present invention Figure 1 A partially enlarged structural diagram of part A in the middle;

[0027] Figure 5 For the present invention Figure 2 A partially enlarged structural diagram of section B;

[0028] Figure 6 For the present invention Figure 3A magnified schematic diagram of part C in the middle section;

[0029] Figure 7 For the present invention Figure 3 A partially enlarged structural diagram of section D;

[0030] Figure 8 This is a schematic diagram of the connection structure between the belt timing pulley and the housing of the present invention;

[0031] Figure 9 This is a cross-sectional view of the mobile platform of the present invention.

[0032] Reference numerals: 100, Main component; 101, Outer shell; 102, Working groove; 103, Mounting groove; 104, Horizontal groove; 105, Communication groove; 106, Mounting bracket; 107, Auxiliary groove; 108, Mating groove; 109, Auxiliary mounting base; 110, Return table; 111, Load-bearing frame; 200, Moving mechanism; 201, Moving platform one; 202, Moving arm; 203, Moving platform two; 204, Movable sleeve; 205, Lead screw one; 206, Connecting frame; 207. Connecting plate one; 208, hook; 209, vertical groove; 210, connecting plate two; 211, horizontal groove; 212, limiting frame; 300, liquid absorption and dehumidification structure; 301, liquid absorption belt; 302, fiber array bristles; 303, sealing frame; 304, air intake channel; 305, belt synchronous pulley; 306, air knife; 307, sealing arc strip; 308, connecting section; 309, elastic sealing plate; 310, horn hole; 311, liquid collection hole; 313, arc-shaped cover; 314, liquid-repellent layer. Detailed Implementation

[0033] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0034] Many specific details are set forth in the following description in order to provide a full understanding of the invention. However, the invention may also be practiced in other ways different from those described herein, and those skilled in the art can make similar extensions without departing from the spirit of the invention. Therefore, the invention is not limited to the specific embodiments disclosed below.

[0035] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places in this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that is mutually exclusive with other embodiments.

[0036] Secondly, the present invention is described in detail with reference to the schematic diagrams. When detailing the embodiments of the present invention, for ease of explanation, the cross-sectional views illustrating the device structure may be partially enlarged, not according to the usual scale. Furthermore, the schematic diagrams are merely examples and should not limit the scope of protection of the present invention. In addition, actual fabrication should include three-dimensional spatial dimensions of length, width, and depth.

[0037] like Figures 1-9 As shown, this invention proposes a biological tissue staining machine, including a main body component 100, a moving mechanism 200, and a liquid absorption and dehumidification structure 300. The main body component 100 includes a shell 101, a working groove 102, a mounting groove 103, a mounting frame 106, and a load-bearing frame 111. The top of the shell 101 has a working groove 102, and the bottom of the working groove 102 has a mounting groove 103. The inner wall of the mounting groove 103 is provided with four load-bearing frames 111, and the mounting frame 106 is installed on the top of the mounting groove 103. The load-bearing frames 111 support the mounting frame 106. The four load-bearing frames 111 are evenly distributed on the inner wall of the mounting groove 103, which can distribute the weight of the mounting frame 106 to different positions in the mounting groove 103, avoid deformation of the mounting frame 106 due to concentrated force, and ensure the stable support of the mounting frame 106 for the tissue bearing structure.

[0038] The bottom of the mounting tank 103 is provided with a liquid absorption and dehumidification structure 300. The liquid absorption and dehumidification structure 300 is located at the bottom of the mounting tank 103 and can directly receive the liquid dripping from the mounting bracket 106, preventing the liquid from accumulating at the bottom of the mounting tank 103, reducing the erosion of the inner wall of the mounting tank 103 by the liquid, and extending the service life of the equipment.

[0039] A moving mechanism 200 is provided on each side of the bottom of the working trough 102. The moving mechanisms 200 are symmetrically arranged on both sides of the working trough 102, which can drive the material transfer operation synchronously from both sides, so that the material support structure is balanced during the movement, avoids the offset caused by unilateral drive, and ensures the accuracy of the material transfer position.

[0040] A horizontal groove 104 is provided on the back of the mounting groove 103. The horizontal groove 104 is slidably connected to the moving mechanism 200. The horizontal groove 104 provides a fixed sliding path for the moving mechanism 200, which can limit the moving direction of the moving mechanism 200, prevent the moving mechanism 200 from shifting laterally during the movement, and ensure that the moving mechanism 200 always moves along the preset trajectory.

[0041] The moving mechanism 200 includes a moving platform 201 and a moving arm 202. The moving arm 202 is provided at one end of the moving platform 201. The moving platform 201 extends into the horizontal groove 104 and is slidably connected to the horizontal groove 104. The moving arm 202 is above the mounting frame 106 and is provided with a material transfer component. The sliding cooperation between the moving platform 201 and the horizontal groove 104 can drive the moving arm 202 and the material transfer component to move stably. Moreover, the moving arm 202 is located above the mounting frame 106, so that the material transfer component can accurately correspond to the tissue on the mounting frame 106 and avoid misalignment during material transfer.

[0042] The material transfer assembly includes a second movable stage 203, a connecting frame 206, a first connecting plate 207, and a hook 208. The second movable stage 203 is movably connected to the movable arm 202. The first connecting plate 207 is slidably connected to one side of the second movable stage 203. A matching hole is provided at the bottom of the second movable stage 203, which is movably connected to the movable arm 202. A vertical groove 209 is provided on one side of the second movable stage 203. The connecting frame 206 is provided at the top of one side of the first connecting plate 207. The top of the connecting frame 206... The end extends into the vertical groove 209, and a linear motor is provided on the inner side of the vertical groove 209. The movable end of the linear motor is connected to one end of the connecting frame 206. Two hooks 208 are provided at the bottom end of the connecting plate 207. The second moving stage 203 is movably connected to the moving arm 202 through the matching hole, which can realize the position adjustment of the second moving stage 203 along the moving arm 202. The linear motor drives the connecting frame 206 to move along the vertical groove 209, which can drive the first connecting plate 207 and the hooks 208 to move up and down.

[0043] A movable wheel is rotatably connected to one side of the movable stage 201. A servo motor is installed inside the movable stage 201. The power output end of the servo motor is connected to the movable wheel. The movable wheel is in frictional connection with the vertical wall inside the horizontal groove 104. A constraint frame is installed on the movable stage 201. A straight groove is opened on the horizontal groove 104. The constraint frame extends into the straight groove and is slidably connected to the straight groove.

[0044] The moving mechanism 200 also includes a limiting frame 212. The limiting frame 212 is fixedly installed on one side of the moving platform 203. The limiting frame 212 is L-shaped and is movably connected to one side of the moving platform 203.

[0045] The L-shaped limiting bracket 212 can block and limit the components on the outside of the moving table 203, preventing the components on the outside from shifting or falling off due to vibration when the moving table 203 is moved or adjusted, thus ensuring the overall structural stability of the material transfer assembly.

[0046] The moving mechanism 200 also includes a second connecting plate 210, a movable sleeve 204, and a first lead screw 205. The second connecting plate 210 is provided on the inner side of the second moving table 203. A transverse groove 211 is provided on one side of the moving arm 202. A circular groove is provided inside the moving arm 202, which is connected to the transverse groove 211. The movable sleeve 204 is movably connected inside the circular groove. The second connecting plate 210 extends from the transverse groove 211 into the circular groove and is fixedly connected to the movable sleeve 204. The first lead screw 205 is rotatably connected to the center of the circular groove. A servo motor is provided at one end of the circular groove, and the power output end of the servo motor is fixedly connected to the first lead screw 205. The servo motor drives the first lead screw 205 to rotate, which can drive the movable sleeve 204 to move precisely along the circular groove. Then, the second connecting plate 210 drives the second moving table 203 to adjust its position along the transverse groove 211. The high precision characteristics of the lead screw drive can ensure the position adjustment accuracy of the second moving table 203 and meet the requirements of fine material transfer.

[0047] Both ends of the belt timing pulley are equipped with sealing rubber rings, which are movably connected to the outer casing 101.

[0048] The liquid absorption dehumidification structure 300 includes a liquid absorption belt 301, a fiber array 302, and belt timing pulleys 305. Several belt timing pulleys 305 are rotatably connected to the bottom of the mounting groove 103. The belt timing pulleys 305 form a circle, and the liquid absorption belt 301 is sleeved on its outer side. The inner side of the liquid absorption belt 301 is provided with connecting teeth that mesh with the outer side of the belt timing pulleys 305. The liquid absorption belt 301 is provided with two liquid absorption parts. The belt timing pulleys 305 and the liquid absorption belt 301 mesh with teeth for transmission, which can prevent belt slippage, ensure the stable rotation of the liquid absorption belt 301, realize the alternating use of the two liquid absorption parts, avoid the need to stop and replace the liquid absorption part after it becomes saturated, and improve the continuity of liquid absorption.

[0049] The liquid absorption and dehumidification structure 300 also includes an air knife 306, a sealing arc strip 307, a horn hole 310, an air intake channel 304, and a sealing frame 303. Cleaning liquid nozzles are distributed on both sides of the air knife 306. The distance between the air knife 306 and the liquid absorption belt 301 is less than one millimeter. A sealing frame 303 is provided in the middle of the mounting groove 103. The two sides of the sealing frame 303 are fixedly connected to one side of the inner wall of the mounting groove 103. The sealing frame 303 is U-shaped. A sealing arc strip 307 is provided at the top of each end of the sealing frame 303. The sealing arc strip 307 is movably connected to the outer side of the belt synchronous pulley 305. 07 is squeezed by the synchronous pulley 305 of the belt. The liquid absorption part includes a liquid collection hole 311, a horn hole 310 and a fiber array 302. A connecting section 308 is provided at each end of the liquid absorption part. An elastic sealing plate 309 is provided on the outside of the connecting section 308. The outer side of the elastic sealing plate 309 protrudes from the outside of the liquid absorption belt 301. The liquid absorption part of the liquid absorption belt 301 is evenly provided with several liquid collection holes 311. Several horn holes 310 are evenly provided on the inner wall of the liquid collection hole 311. The inner wall of the liquid collection hole 311 is provided with fiber array 302. The liquid absorption part of the liquid absorption belt 301 is located directly below or above the mounting frame 106.

[0050] The gap between the air knife 306 and the liquid suction belt 301 is less than one millimeter, which can ensure that the airflow sprayed by the air knife 306 is precisely applied to the fiber array fibers 302, accelerating liquid separation. The cleaning liquid nozzle can directly spray cleaning liquid onto the fiber array fibers 302, improving cleaning efficiency.

[0051] The U-shaped enclosure 303, together with the sealing arc strip 307 and the belt synchronous pulley 305, compresses and seals to prevent liquid or airflow from overflowing from the liquid absorption area; the liquid collection hole 311 can collect dripping liquid; the horn hole 310 can expand the range of airflow or cleaning fluid; the fiber array 302 can enhance the liquid absorption capacity; the elastic sealing plate 309 protrudes from the liquid absorption belt 301 and can fit against the inner wall of the mounting groove 103 when the liquid absorption part moves, reducing leakage from gaps.

[0052] An auxiliary groove 107 is provided at each end of the bottom of the mounting groove 103. The auxiliary groove 107 is trapezoidal in shape and is also provided with a belt synchronous pulley 305. The inclined inner wall of the trapezoidal auxiliary groove 107 can guide the connecting section 308, so that the connecting section 308 can be smoothly inserted or removed. The belt synchronous pulley 305 in the groove can assist the liquid suction belt 301 to rotate, reducing the frictional wear of the edge of the liquid suction belt 301.

[0053] The main component 100 also includes mating grooves 108 and auxiliary mounting seats 109. Several mating grooves 108 are evenly arranged on the mounting frame 106, and two auxiliary mounting seats 109 are provided at both ends of the inner wall of the mating groove 108. Multiple mating grooves 108 can realize the simultaneous installation of multiple sets of tissue support structures, thereby improving the dyeing efficiency of the equipment. The two auxiliary mounting seats 109 on the inner wall of the mating groove 108 can position and support the tissue support structure, preventing the tissue support structure from shifting due to vibration during the dyeing process.

[0054] The enclosure 303, sealing arc strip 307, connecting section 308, elastic sealing plate 309 and belt synchronous pulley 305 form a sealing layer, dividing the mounting groove 103 into two parts, so that the bottom of the mounting groove 103 forms a closed cavity.

[0055] The fiber array 302 is configured with both type A and type B fibers, which are uniformly mixed in a ratio of type A to type B of 1:1.5~2. The two types of fibers are randomly distributed throughout the fiber bundle, with gaps to ensure airflow penetration. The dense structure of type B fibers binds organic liquids at all times, while the hydrophilicity of type A fibers can adsorb water. This can handle situations where the liquid is a mixture of water and organic liquids, or where both liquids need to contact the fiber structure at the same time.

[0056] Type A, suitable for aqueous solutions: Made of hydrophilic modified nylon or degreased wool, with a diameter of 8~20μm and a density of 600~1200 strands / mm. 2 Its core function is to hydrophilically adsorb water, while the large gaps ensure airflow penetration.

[0057] Suitable for organic liquids, type B: Made of polytetrafluoroethylene or solvent-resistant nylon, with a diameter of 5~10μm and a density of 1200~2000 strands / mm. 2 Its core function is solvent resistance, and its dense structure binds organic liquids.

[0058] The gaps formed by the two types of hairs range from 20 to 60 μm, a size much larger than the free path of airflow molecules, allowing airflow to pass through easily. The diameter and number of type A hairs are 8 μm and 800 hairs / mm, respectively. 2 The diameter and number of type B hairs are 5μm and 1800 hairs / mm, respectively. 2 It occupies only 7.55% of the total area, with gaps of 2 to 3 μm, which fully meets the requirements for airflow penetration.

[0059] A pressure sensor is installed inside the auxiliary tank 107. The suction channel 304 and the air knife 306 work together to maintain the average air pressure inside the auxiliary tank 107 at 96% of the external atmospheric pressure, forming a micro-vacuum. This avoids excessive pressure difference between the top and bottom of the installation tank 103, which would create strong airflow and reduce the evaporation of the dyeing solution.

[0060] The cleaning liquid nozzle can spray a mixture of alcohol and water onto the fiber array fibers 302 to clean them.

[0061] The belt pulley 305, which is connected to the sealing arc strip 307, is connected to the power output end of the motor. The liquid-repellent layer 314 is a polyurethane film modified with fluorinated multi-walled carbon nanotubes / nano-silica hybrid particles.

[0062] Substrate body: The elastic memory polyurethane film with an elongation at break of ≥300% and a deformation recovery rate of ≥95% is selected to enable the arc-shaped cover to maintain its arc shape when no external force is applied, and at the same time, it has the characteristic of rapid rebound after extrusion, ensuring that it can restore its original shape after the liquid collection hole is closed.

[0063] Reinforcing layer: Built-in glass fiber reinforced polyester fiber mesh with tensile strength ≥50MPa and thickness 0.1 to 0.2mm, which can enhance the structural stability of the arc-shaped cover, avoid arc collapse or deformation after long-term repeated compression, and ensure the consistency of arc shape during long-term use;

[0064] Connection Structure Material: The connection between the arc-shaped cap and the absorbent belt uses a medical-grade silicone hinge, which can rotate 180° to meet the angle requirements for collapsing and sealing the collection hole when squeezed. A stainless steel micro-spring is embedded in the hinge to provide elastic support for the arc-shaped cap's return to its original position after being released from compression, ensuring the arc-shaped cap independently achieves the "shape retention-sealing-reset" function. A hydrophobic layer 314 is coated on the inner surface of the arc-shaped cap 313 facing the collection hole 311. Liquid droplets falling onto the hydrophobic layer 314 on the arc-shaped cap 313 are guided to the collection holes 311 on both sides of the arc-shaped cap 313, preventing contamination of the connection between the collection holes 311 and also preventing contamination of the non-hydrophobic layer 314 side of the arc-shaped cap 313. The arc-shaped cap 313 curls into an arc shape, protecting the non-hydrophobic layer 314 on the arc-shaped cap 313.

[0065] The specific implementation method is as follows: During the drying of the fiber array 302, the suction channel 304 continuously draws air, the air knife 306 is connected to a high-pressure air pipe, and the air knife 306 intermittently sprays high-pressure air into the horn hole 310. The high-pressure air enters the liquid collection hole 311 through the horn hole 310 and passes through the fiber array 302, which accelerates the separation of liquid in the fiber array 302. The high-speed airflow with a flow rate greater than 5m / s can overcome the capillary force and blow away the liquid in the gap between the fibers, so that the fiber array 302 can restore its water absorption capacity.

[0066] When the fiber array 302 of the liquid absorption section reaches 80% adsorption saturation, the control system triggers the belt synchronous pulley 305 to rotate. The belt synchronous pulley 305 drives the liquid absorption belt 301 to run, causing the positions of the two liquid absorption sections to be reversed. The liquid absorption section in the upper layer can absorb the dripping liquid, avoiding liquid accumulation, reducing pollution, reducing liquid evaporation, reducing humidity in the working tank 102, and reducing the amount of dye evaporation. When the liquid absorption dehumidification structure 300 is in working condition, the connecting sections 308 at both ends of the liquid absorption section are partially inserted into the auxiliary tank 107. The elastic sealing plate 309 is partially squeezed and deformed against the inner wall of the auxiliary tank 107, filling the gap between the connecting section 308 and the inner wall of the auxiliary tank 107, thus sealing it.

[0067] During the process of the liquid absorption part of the liquid absorption and dehumidification structure 300 entering the auxiliary tank 107, the return table 110 squeezes the arc-shaped cover 313, causing the arc-shaped cover 313 to fall down and stick to the opening of the closed liquid collection hole 311. When the arc-shaped cover 313 enters the auxiliary tank 107 along with the liquid absorption part of the liquid absorption and dehumidification structure 300, the arc-shaped cover 313 keeps the liquid collection hole 311 closed, so that the liquid in the liquid collection hole 311 will not contaminate the inner wall of the auxiliary tank 107. The liquid nozzles on both sides of the cleaning air knife first spray alcohol-water mixture onto the fiber array fibers 302. After soaking for 30 seconds, the air knife 306 sprays a high-speed airflow of 5m / s to blow away the residual liquid in the gaps between the fibers, realizing continuous operation of cleaning and drying. The volume ratio of the mixed liquid is 1:1.

[0068] It should be understood that numerous specific implementation decisions can be made during the development of any practical implementation, such as in any engineering or design project. Such development efforts may be complex and time-consuming, but for those skilled in the art who benefit from this disclosure, the development effort will be a routine work of design, manufacturing, and production without requiring much experimentation.

[0069] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit it. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, and all such modifications or substitutions should be covered within the scope of the claims of the present invention.

Claims

1. A biological tissue staining machine, characterized in that: The system includes a main body assembly (100), a moving mechanism (200), and a liquid absorption and dehumidification structure (300). The main body assembly (100) includes a shell (101), a working groove (102), a mounting groove (103), a mounting bracket (106), and a load-bearing frame (111). The top of the shell (101) has a working groove (102), and the bottom of the working groove (102) has a mounting groove (103). The inner wall of the mounting groove (103) is provided with four load-bearing frames (111), and the top of the mounting groove (103) is equipped with a mounting bracket (106). The load-bearing frames (111) support... Mounting bracket (106); the bottom of mounting groove (103) is provided with liquid absorption and dehumidification structure (300); a moving mechanism (200) is provided on both sides of the bottom of working groove (102); the moving mechanism (200) includes a moving platform (201) and a moving arm (202), one end of the moving platform (201) is provided with the moving arm (202), the moving platform (201) extends into the horizontal groove (104), the moving platform (201) is slidably connected to the horizontal groove (104), the moving arm (202) is above the mounting bracket (106), and the moving arm (202) is provided with a liquid absorption and dehumidification structure (300). Material transfer assembly; liquid absorption and dehumidification structure (300) includes a liquid absorption belt (301), fiber array hairs (302), and belt timing pulleys (305). Several belt timing pulleys (305) are rotatably connected to the bottom of the mounting groove (103). The belt timing pulleys (305) form a circle, and the liquid absorption belt (301) is sleeved on its outer side. The inner side of the liquid absorption belt (301) is provided with connecting teeth that mesh with the outer side of the belt timing pulleys (305). The liquid absorption belt (301) is provided with two liquid absorption parts, which include a liquid collection hole (311), a horn hole (310), and a fiber array hairs (302). 302), a connecting section (308) is provided at each end of the liquid absorption part. An elastic sealing plate (309) is provided on the outside of the connecting section (308). The outer side of the elastic sealing plate (309) protrudes from the outside of the liquid absorption belt (301). The liquid absorption part of the liquid absorption belt (301) is evenly provided with several liquid collection holes (311). Several horn holes (310) are evenly provided on the inner wall of the liquid collection hole (311). The inner wall of the liquid collection hole (311) is provided with fiber array hairs (302). The liquid absorption part of the liquid absorption belt (301) is located directly below or directly above the mounting frame (106).

2. The biological tissue staining machine according to claim 1, characterized in that: A horizontal groove (104) is provided on the back of the mounting groove (103), and the horizontal groove (104) is slidably connected to the moving mechanism (200).

3. The biological tissue staining machine according to claim 1, characterized in that: The material transfer assembly includes a second moving platform (203), a connecting frame (206), a first connecting plate (207), and hooks (208). The second moving platform (203) is movably connected to the moving arm (202). The first connecting plate (207) is slidably connected to one side of the second moving platform (203). A matching hole is opened at the bottom of the second moving platform (203), and the matching hole is movably connected to the moving arm (202). A vertical groove (209) is opened on one side of the second moving platform (203). A connecting frame (206) is provided on the top of one side of the first connecting plate (207). The top of the connecting frame (206) extends into the vertical groove (209). A linear motor is provided inside the vertical groove (209). The movable end of the linear motor is connected to one end of the connecting frame (206). Two hooks (208) are provided at the bottom of the first connecting plate (207).

4. A biological tissue staining machine according to claim 3, characterized in that: The moving mechanism (200) also includes a limiting frame (212). The limiting frame (212) is fixedly installed on one side of the moving platform (203). The limiting frame (212) is L-shaped.

5. A biological tissue staining machine according to claim 3, characterized in that: The moving mechanism (200) also includes a second connecting plate (210), a movable sleeve (204), and a first lead screw (205). The second connecting plate (210) is provided on the inner side of the second moving platform (203). A transverse groove (211) is provided on one side of the moving arm (202). A circular groove is provided inside the moving arm (202). The circular groove is connected to the transverse groove (211). The movable sleeve (204) is movably connected inside the circular groove. The second connecting plate (210) extends from the transverse groove (211) into the circular groove and is fixedly connected to the movable sleeve (204). The first lead screw (205) is rotatably connected to the center part of the circular groove. A servo motor is provided at one end of the circular groove. The power output end of the servo motor is fixedly connected to the first lead screw (205).

6. A biological tissue staining machine according to claim 1, characterized in that: The liquid absorption and dehumidification structure (300) also includes an air knife (306), a sealing arc strip (307), a horn hole (310), an air intake channel (304), and a closed frame (303). Cleaning liquid nozzles are distributed on both sides of the air knife (306). The distance between the air knife (306) and the liquid absorption belt (301) is less than one millimeter. A closed frame (303) is provided in the middle of the mounting groove (103). The two sides of the closed frame (303) are fixedly connected to one side of the inner wall of the mounting groove (103). The closed frame (303) is U-shaped. A sealing arc strip (307) is provided at the top of each end of the closed frame (303). The sealing arc strip (307) is movably connected to the outer side of the belt synchronous pulley (305). The sealing arc strip (307) is squeezed against the belt synchronous pulley (305). An auxiliary groove (107) is provided at each end of the bottom of the mounting groove (103). The auxiliary groove (107) is trapezoidal in shape and a belt timing pulley (305) is also provided inside the auxiliary groove (107).

7. A biological tissue staining machine according to claim 1, characterized in that: The main component (100) also includes a mating groove (108) and an auxiliary mounting base (109). Several mating grooves (108) are evenly arranged on the mounting bracket (106), and two auxiliary mounting bases (109) are provided at both ends of the inner wall of the mating groove (108).

8. A biological tissue staining machine according to claim 1, characterized in that: The liquid absorption and dehumidification structure (300) also includes an arc-shaped cover (313) and a liquid-repellent layer (314). A return platform (110) is provided on one side of the mounting groove (103). The return platform (110) is located at the opening of the auxiliary groove (107). The return platform (110) is a triangular prism. The end of the return platform (110) away from the inner wall of the mounting groove (103) is rounded. An arc-shaped cover (313) is provided on one end of the liquid collection hole (311). The bottom of the return platform (110) is movably connected to the elastic sealing plate (309) and the arc-shaped cover (313). A liquid-repellent layer (314) is provided on one side of the arc-shaped cover (313). The shape of the arc-shaped cover (313) is three-quarters of a circle.

Citation Information

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