A stem cell injection structure and a neurosurgical head frame

Abstract

This invention relates to the medical field and discloses a stem cell injection structure and a neurosurgical head frame. It includes an injection support, a lifting component, an injection depressor assembly, an injection drive assembly, and a syringe. The lifting component and the injection depressor assembly are slidably connected to the injection support and arranged at intervals. The syringe barrel is detachably fixed to the lifting component, and the syringe piston rod abuts against the injection depressor assembly. The injection drive assembly is movably connected to the injection support, and both the lifting component and the injection depressor assembly are connected to the injection drive assembly. When the injection drive assembly operates, it drives the lifting component and the syringe barrel to move closer to the injection depressor assembly, while simultaneously driving the syringe piston rod to move closer to the lifting component. This invention achieves the effect of uniform injection and uniform lifting and withdrawal, resulting in a more uniform overall density of the injected material; improving the accuracy of the injection content; making it easier to accurately control the injection content; and improving the therapeutic effect.

Description

Technical Field

[0001] This invention relates to the field of medical technology, and more specifically, to a stem cell injection structure and a neurosurgical head frame. Background Technology

[0002] Stem cells are a special type of cell with the potential for self-replication and differentiation. In neurosurgery, minimally invasive surgery is often used to inject stem cells into corresponding nuclei within the body as a treatment method. In some cases, it is necessary to precisely inject stem cells into the lesion, causing the injected stem cells to form columnar cell clusters to bridge the damaged area. Simultaneously, the syringe needs to be moved a specific distance to inject into at least three nuclei. Currently, during injection, the doctor inserts the syringe needle into the lesion and manually injects stem cells while simultaneously lifting the syringe upwards to form columnar stem cells. However, throughout the procedure, the doctor's hands must remain above the operating table in a sterile environment, preventing effective arm relaxation. Furthermore, the movement of the syringe relies on direct manipulation by the doctor's hands, resulting in poor uniformity of the injected columnar stem cells and affecting the treatment outcome. In addition, the nuclei in the brain are crescent-shaped, and the injection port of the existing syringe needle is located at the lowest end of the syringe and injects vertically. If the needle is inserted into the nucleus and is located in a position where the nucleus wall is relatively thin, the nucleus is prone to rupture during injection, which will affect the treatment effect. Summary of the Invention

[0003] To address at least one of the aforementioned problems, the present invention first provides a stem cell injection structure, comprising an injection scaffold, a lifting member, an injection depressor assembly, an injection drive assembly, and a syringe. The lifting member and the injection depressor assembly are both slidably connected to the injection scaffold. The syringe includes a syringe barrel, a piston rod, and an injection needle. The piston rod is slidably inserted into the syringe barrel, the syringe barrel is detachably connected to the lifting member and moves synchronously therewith, the injection depressor assembly abuts against the top of the piston rod, and the injection needle is connected to the end of the syringe barrel away from the piston rod. The injection drive assembly is connected to the injection scaffold. The injection support is rotatably connected, and both the lifting member and the injection pressing assembly are movably connected to the injection driving assembly. During injection, after the injection driving assembly is driven to rotate, the lifting member drives the syringe to move upward relative to the injection support, while the injection pressing assembly drives the piston rod to move downward relative to the injection support. An injection outlet is provided on the side wall of the end of the injection needle away from the syringe, through which stem cells or drugs are suitable for being discharged from the syringe. The injection support is adapted to be rotatably connected to the surgical head frame about the injection needle as the rotation axis, and is used to adjust the orientation of the injection outlet.

[0004] Optionally, the surgical head frame is provided with a rotation angle reference line, and the injection bracket is provided with a rotation angle scale line that cooperates with the rotation angle reference line.

[0005] Optionally, a needle holder is detachably connected to the injection support, the needle holder is located below the lifting member, and a sheath needle is detachably inserted into the needle holder. The sheath needle is adapted to be inserted into the nucleus to form an injection cavity, the injection needle is inserted into the sheath needle, and the injection outlet protrudes from the sheath needle. The injection needle and the sheath needle are in clearance fit.

[0006] Optionally, the needle holder has a plurality of positioning holes spaced apart on the side near the lifting member, and the plurality of positioning holes all penetrate the needle holder. The sheath needle tube is adapted to be inserted into any one of the positioning holes, and the end of the sheath needle tube away from the lifting member is located below the needle holder.

[0007] Optionally, the injection driving assembly includes a forward threaded rod and a reverse threaded rod, which are connected and rotate synchronously. Both the forward and reverse threaded rods are rotatably connected to the injection bracket. A lifting block is sleeved on and threadedly connected to the reverse threaded rod. The lifting member is slidably connected to the lifting block from left to right. After the reverse threaded rod rotates, it will drive the lifting block to drive the lifting member to move up and down synchronously. The injection pressing assembly is threadedly connected to the forward threaded rod to drive the injection pressing assembly to move relative to the injection bracket.

[0008] Optionally, a protrusion is fixedly provided on the side of the lifting block near the lifting member, and a matching long groove is provided on the lifting member, into which the protrusion is inserted; a horizontal driving member is rotatably provided on the lifting member, the horizontal driving member passes through the protrusion and is threadedly connected to the protrusion, and one end of the horizontal driving member passes through the lifting member in a cantilevered state. When the horizontal driving member is driven to rotate, the lifting member will drive the syringe to move horizontally relative to the injection bracket.

[0009] Optionally, the pitch of the forward threaded rod is greater than or equal to the pitch of the reverse threaded rod.

[0010] Optionally, the injection pressing assembly includes a sliding member and an abutment plate. The sliding member is threadedly connected to the positive threaded rod, and the abutment plate is slidably connected to the sliding member to adapt to the piston rod extending to different lengths. When the positive threaded rod is driven to rotate, the positive threaded rod drives the sliding member to move the abutment plate and the piston rod.

[0011] Optionally, the injection pressing assembly further includes an extension rod, which is connected to and moves synchronously with the sliding member. The abutment plate is sleeved on and directionally slides on the extension rod. The abutment plate is provided with a locking member, which is adapted to lock or unlock the movement of the abutment plate.

[0012] Compared with the prior art, the beneficial technical effects of the present invention are as follows:

[0013] 1. The injection stent can be connected to the surgical head frame or operating table and remains relatively fixed after the angle and position are adjusted. After the injection stent is connected to the surgical head frame and remains fixed, the injection drive component will drive the lifting component and the injection pressing component to move closer to each other. This causes the injection pressing component to push the piston rod of the syringe to inject, while the lifting component drives the syringe barrel to rise, forming an effect of injecting and withdrawing at the same time. Under the action of the injection drive component, the lifting component and the injection pressing component keep the injection content and withdrawal distance at a stable ratio, thereby making the overall density of the injected stem cells or drugs more uniform and improving the treatment effect.

[0014] 2. The number of rotations of the injection drive component is always directly proportional to the rising distance of the lifting component and the falling distance of the injection pressing component. The operator can determine the rising distance of the lifting component by rotating the injection drive component, and thus accurately control the length of the columnar stem cells or drugs. In addition, according to the different pitches of the forward and reverse threaded rods, the falling speed of the piston rod and the rising speed of the syringe can be controlled, thereby meeting the needs of injecting stem cell columns of different diameters and corresponding lengths.

[0015] 3. Before injection, insert a plug into the cannula of the surgical head to block the inside of the cannula. Then, insert the cannula and the plug into the corresponding nucleus. After that, remove the plug, so that the part of the cannula inserted into the nucleus forms an injection cavity. According to the injection requirements, during injection, the base of stem cells or drugs needs to be directly inserted into the nucleus. Therefore, the injection outlet needs to protrude from the cannula. However, since the injection outlet is located on the side wall of the injection needle, it will impact the nucleus at the beginning of the injection. If the injection port faces the side of the nucleus with thinner walls, it is easy to cause the nucleus to rupture. Therefore, the injection support and injection needle can be rotated by the rotating structure on the surgical head frame with the injection needle as the rotation axis. At the same time, the rotation angle can be precisely controlled by the rotation angle baseline and rotation angle scale line, so that the injection opening faces the side of the nucleus with thicker walls, reducing the risk of nucleus rupture and improving the treatment effect.

[0016] 4. Since the injection outlet is located on the side wall of the injection needle, after the injection opening moves into the inside of the cannula during injection, the stem cells or drugs will impact the inner wall of the cannula under pressure, instead of directly impacting the nucleus. On the one hand, the cannula protects the nucleus, and on the other hand, it constrains the injected stem cells or drugs, allowing them to form a relatively compact and uniformly dense column.

[0017] 5. Compared with the structure of multi-stage transmission, the lifting component and the syringe are connected. The rotary injection drive component can directly drive the lifting component to move the syringe up and back. The rotary horizontal drive component can directly drive the lifting component to move the syringe horizontally. This can improve the accuracy of syringe movement adjustment and the accuracy of syringe movement adjustment, and also improve the convenience of moving the syringe.

[0018] 6. Compared with applying directional thrust to control the injection content of the syringe, the structure that controls the injection content by rotating the lifting component and the injection pressing component is easier to control the injection content accurately. In addition, the threaded connection structure allows the lifting component and the injection pressing component to stop moving stably and be locked when the injection drive component is not rotated, thus achieving the effect of precise control of the injection volume.

[0019] In addition, the present invention provides a neurosurgical head frame, including the stem cell injection structure described above.

[0020] Compared to existing technologies, the neurosurgical head frame described in this invention has the same advantages as the aforementioned stem cell injection structure, which will not be repeated here. Attached Figure Description

[0021] Figure 1 The structure of the stem cell injection structure in the embodiment of the present invention. Figure 1 ;

[0022] Figure 2 The structure of the stem cell injection structure in the embodiment of the present invention. Figure 2 ;

[0023] Figure 3 This is a structural diagram of the injection support, lifting member, and injection driving assembly in an embodiment of the present invention;

[0024] Figure 4 This is a structural diagram of the injection driving component in an embodiment of the present invention;

[0025] Figure 5 This is an exploded view of the injection support and lifting component in an embodiment of the present invention;

[0026] Figure 6This is an exploded view of the lifting member, set bolt, and horizontal drive member in an embodiment of the present invention;

[0027] Figure 7 for Figure 3 Enlarged view of section A in the middle;

[0028] Figure 8 This is a side view of the stem cell injection structure in an embodiment of the present invention;

[0029] Figure 9 for Figure 8 Enlarged view of section B;

[0030] Figure 10 for Figure 8 Enlarged view of section C

[0031] Figure 11 This is a partial enlarged view of an embodiment of the present invention;

[0032] Figure 12 This is an exploded view of the injection needle and the cannula of the sheath in an embodiment of the present invention;

[0033] Figure 13 This is an exploded view of the injection stent and needle holder in an embodiment of the present invention.

[0034] Explanation of reference numerals in the attached drawings: 1. Injection holder; 11. Mounting groove; 12. Rotation reference line; 13. First height scale line; 14. Second height scale line; 15. Lifting block; 151. Protrusion; 152. Horizontal reference line; 16. Base; 161. Limiting block; 162. Rotation angle scale line; 17. Needle holder; 171. Positioning hole; 172. Limiting ring groove; 173. Blocking ring; 18. Needle tube; 2. Lifting component; 21. Mounting hole; 22. Set bolt; 23. Lifting base 24. Horizontal scale line; 25. Fitting groove; 26. Bearing hole; 3. Injection pressing assembly; 31. Sliding component; 311. Moving reference line; 32. Abutment plate; 33. Extension rod; 34. Tightening bolt; 4. Injection drive assembly; 41. Forward threaded rod; 42. Reverse threaded rod; 43. Rotary cap; 431. Rotating scale line; 44. Coupling; 5. Syringe; 51. Syringe; 52. Piston rod; 53. Injection needle; 531. Injection outlet; 6. Horizontal drive component. Detailed Implementation

[0035] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the following description is provided in conjunction with the accompanying drawings. Figures 1-13 This application will be described in further detail.

[0036] The accompanying drawings of this embodiment of the invention provide a coordinate system XYZ, where the positive direction of the X-axis represents the right, the negative direction of the X-axis represents the left, the positive direction of the Y-axis represents the front, the negative direction of the Y-axis represents the back, the positive direction of the Z-axis represents the top, and the negative direction of the Z-axis represents the bottom.

[0037] In a first aspect, embodiments of the present invention provide a stem cell injection structure, referring to... Figures 1 to 3 The stem cell injection structure includes an injection scaffold 1, a lifting member 2, an injection depressor 3, an injection drive assembly 4, and a syringe 5. The injection scaffold 1 can be connected to an operating table or surgical head frame to adjust its position and angle. The injection depressor 3 is located above and spaced apart from the lifting member 2, and both the lifting member 2 and the injection depressor 3 are slidably connected to the injection scaffold 1. The injection drive assembly 4 is rotatably connected to the injection scaffold 1, and both the lifting member 2 and the injection depressor 3 are threadedly connected to the injection drive assembly 4. The syringe 5 includes a syringe barrel 51, a piston rod 52, and an injection needle 53. The syringe barrel 51 contains stem cells or drugs. The piston rod 52 is slidably inserted into the syringe barrel 51. The injection needle 53 is connected and communicates with the end of the syringe barrel 51 away from the piston rod 52. By depressing the piston rod 52, the stem cells or drugs in the syringe barrel 51 can be discharged through the injection needle 53 and injected into the nucleus. The syringe 51 and the lifting component 2 are detachably connected and move synchronously. The injection pressing component 3 abuts against the top of the piston rod 52. During injection, after driving the injection driving component 4 to rotate, the lifting component 2 drives the syringe 51 to move upward relative to the injection support 1. At the same time, the injection pressing component 3 drives the piston rod 52 to move downward relative to the injection support 1, creating an effect of simultaneous injection and lifting and withdrawal. This allows the injected stem cells or drugs to form a columnar body with relatively uniform density. The entire operation only requires driving the injection driving component 4 to rotate, making it convenient and highly precise.

[0038] The lifting member 2 is rotatably equipped with a horizontal driving member 6, which is threadedly connected to the injection bracket 1. When the horizontal driving member 6 is driven to rotate, the lifting member 2 will be moved a set distance in the horizontal direction relative to the injection bracket 1 to perform secondary or multiple injections.

[0039] The lifting member 2 is located on the front side of the base. The top of the lifting member 2 has a mounting hole 21 for the detachable insertion of the syringe 51. The mounting hole 21 includes a first insertion hole and a second insertion hole arranged concentrically. The diameter of the first insertion hole is larger than the diameter of the second insertion hole. The second insertion hole is located at the bottom of the first insertion hole and penetrates through the lifting member 2. The diameter of the second insertion hole is smaller than the outer diameter of the syringe 51. The syringe 51 is inserted into the first insertion hole, with its bottom abutting against the bottom of the first insertion hole and unable to enter the second insertion hole. The injection needle 53 passes through the second insertion hole and is located below the lifting member 2. This limits the insertion depth of the syringe 51, ensuring the positional accuracy of the syringe 51 after each insertion and removal, and ensuring the protruding length of the injection needle 53, which is beneficial for the operator to control the insertion position of the injection needle 53.

[0040] Reference Figures 1 to 5 The outer wall of the lifting component 2 has at least two threaded holes spaced apart circumferentially. Each threaded hole communicates with the first insertion hole, and a set bolt 22 is threaded into each threaded hole. The set bolt 22 holds the syringe 5 tightly within the mounting hole 21. When the syringe 5 needs to be removed after injection, simply rotate the set bolt 22 to loosen it, and then pull the syringe 51 out of the mounting hole 21. The operation is convenient.

[0041] Reference Figures 1 to 2 The injection pressing assembly 3 includes a sliding member 31, an abutment plate 32, and an extension rod 33. Since the lifting member 2 is located in front of the injection support 1, the sliding member 31 is also located in front of the injection support 1. The extension rod 33 is located at the top of the sliding member 31, and its bottom is inserted into and threadedly connected to the sliding member 31. The extension rod 33 extends vertically. The abutment plate 32 is fitted onto the extension rod 33 and can be adjusted and locked along the length of the extension rod 33. A sliding groove is formed at the bottom of the extension rod 33. The length of the sliding groove is the same as the direction in which the lifting member 2 slides horizontally. The top of the piston rod 52 is inserted into the sliding groove and abuts against the bottom of the groove. When the injection driving assembly 4 drives the sliding member 31 to descend, the sliding member 31 drives the extension rod 33 and the abutment plate 32 to descend synchronously, thereby pushing the piston rod 52 to descend and achieve injection.

[0042] Since the piston rod 52 needs to abut against the abutment plate 32, and the abutment plate 32 is located above the sliding member 31, the sliding member 31 has a notch that extends vertically through the sliding member 31 to allow space for the piston rod 52. Different treatment scenarios require different amounts of stem cells, so the length of the piston rod 52 extending from the syringe 5 also varies. Therefore, by adjusting the length of the abutment plate 32 on the extension rod 33, it can be adapted to match the piston rod 52 of the corresponding length, making it widely applicable.

[0043] Reference Figures 1 to 2The extension rod 33 has an elongated, slotted cross-section. The top of the abutment plate 32 has a through hole adapted to the extension rod 33, which extends vertically through the abutment plate 32, preventing relative rotation of the abutment plate 32 after the extension rod 33 is inserted into the through hole. The piston rod 52 abuts against the side of the abutment plate 32 closest to the lifting member 2. A locking element is threaded onto the side wall of the abutment plate 32. In this embodiment, the locking element is preferably a locking bolt 34, which is inserted into the through hole and abuts against the extension rod 33, thereby locking the abutment plate 32 at any position after it has abutted against the corresponding piston rod 52. To move the abutment plate 32, simply loosen the locking bolt 34.

[0044] Reference Figures 1 to 4 The injection support 1 has a mounting groove 11 on its front side, which extends through the injection support 1 in the front-to-back direction. A portion of the injection drive assembly 4 is rotatably mounted within the mounting groove 11, resulting in a smaller overall volume of the injection structure. The injection drive assembly 4 includes a forward threaded rod 41, a reverse threaded rod 42 (thread not shown), and a cap 43, all rotatably connected to the injection support 1. Both the forward threaded rod 41 and the reverse threaded rod 42 are located within the mounting groove 11, with the forward threaded rod 41 positioned above the reverse threaded rod 42. The threads on the forward threaded rod 41 are opposite to those on the reverse threaded rod 42, and the forward threaded rod 41 and the reverse threaded rod 42 are connected and rotate synchronously. A lifting block 15 is fitted onto and threadedly connected to the reverse threaded rod 42. The lifting block 15 is located within the mounting groove 11, and a lifting member 2 is located in front of the lifting block 15. The lifting member 2 and the lifting block 15 are connected by a horizontal drive member 6 to achieve synchronous lifting. One side of a sliding member 31 is inserted into the mounting groove 11 and threadedly connected to the forward threaded rod 41. The nut 43 is located at the top of the injection holder 1. The end of the forward threaded rod 41 near the nut 43 passes through the injection holder 1 and is connected to the nut 43, rotating synchronously. During injection, the operator can manually drive the nut 43 to rotate, which in turn drives the forward threaded rod 41 and the reverse threaded rod 42 to rotate. The forward threaded rod 41 drives the injection pressing assembly 3 to move downward, while the reverse threaded rod 42 drives the lifting block 15 to move the lifting component 2 upward.

[0045] The injection holder 1 has a first through hole at its top, which communicates with the mounting groove 11. A first bearing is installed inside the first through hole, and the top of the positive threaded rod 41 is inserted into the first bearing, passing through the first through hole and the first bearing and exposed outside the injection holder 1. A cap 43 is fitted onto the portion of the positive threaded rod 41 exposed outside the injection holder 1. At least two set screw threaded holes are circumferentially spaced on the outer wall of the cap 43, and these set screw threaded holes communicate with the interior of the cap 43. A set screw is threaded into each set screw threaded hole, and the set screw abuts against the positive threaded rod 41 located inside the cap 43, thereby driving the positive threaded rod 41 to rotate when the cap 43 is rotated.

[0046] Reference Figures 2 to 5A coupling 44 is fitted at the bottom of the forward threaded rod 41. A first setter screw is threaded onto the coupling 44, and the first setter screw abuts against the forward threaded rod 41 inserted inside the coupling 44, allowing the coupling 44 to rotate synchronously with the forward threaded rod 41. A reverse threaded rod 42 is inserted into the bottom of the coupling 44, and a second setter screw is threaded onto the coupling 44. The second setter screw abuts against the reverse threaded rod 42 inserted inside the coupling 44, allowing the reverse threaded rod 42 to rotate synchronously with the coupling 44. A second through hole is opened at the bottom of the injection bracket 1, communicating with the mounting groove 11. A second bearing is installed in the second through hole, and the bottom end of the reverse threaded rod 42 is inserted into the second bearing. A cover plate is bolted to the bottom of the injection bracket 1 to cover the opening of the second through hole, preventing the second bearing from falling out. Thus, by driving the nut 43, the forward threaded rod 41 and the reverse threaded rod 42 can rotate synchronously.

[0047] Reference Figures 2 to 5 The two outer walls of the lifting block 15 abut against the corresponding groove walls of the mounting groove 11 on the left and right sides, respectively, and the lifting member 2 is in contact with the front side of the injection bracket 1. Thus, when the reverse threaded rod 42 rotates, the lifting block 15 and the lifting member 2 will not rotate synchronously with the reverse threaded rod 42, but will move stably along the length of the mounting groove 11. Similarly, the portion of the sliding member 31 located on the front side of the injection bracket 1 abuts against the front side of the injection bracket 1, and the portion of the sliding member 31 inserted into the mounting groove 11 abuts against the groove walls in the left and right directions of the mounting groove 11. Thus, when the forward threaded rod 41 rotates, the sliding member 31 will not rotate synchronously with the forward threaded rod 41, but will move stably along the length of the mounting groove 11.

[0048] The pitch of the forward thread rod 41 can be greater than or equal to the pitch of the reverse thread rod 42. When the pitch of the forward thread rod 41 is greater than that of the reverse thread rod 42, the different pitches of the forward and reverse thread rods 41 can control the descent speed of the piston rod 52 and the ascent speed of the syringe 51, thereby meeting the needs of injecting stem cell columns of different diameters and corresponding lengths. When the pitch of the forward thread rod 41 is equal to that of the reverse thread rod 42, the descent speed of the piston rod 52 and the ascent speed of the syringe 51 are the same, which is suitable for injection scenarios with special requirements. In this embodiment, it is preferred that the pitch of the forward thread rod 41 is greater than that of the reverse thread rod 42.

[0049] In another embodiment, the injection driving assembly 4 includes a first connecting rod, a second connecting rod, and a third connecting rod. The third connecting rod is slidably mounted on the injection support 1 in a left-right direction. One end of the first connecting rod is hinged to the lifting member 2, and the other end is hinged to the third connecting rod. The first connecting rod is hinged to the injection pressing assembly 3, and the other end is hinged to the third connecting rod. When the third connecting rod is manually slid, the first connecting rod can be driven to raise the lifting member 2; the second connecting rod can drive the injection pressing assembly 3 to lower.

[0050] In another embodiment, the injection drive assembly 4 includes a first connecting rod, a second connecting rod, and a knob. The knob is rotatably located in front of the injection holder 1. One end of the first connecting rod is hinged to the lifting member 2, and the other end is hinged to the eccentric part of the knob. One end of the second connecting rod is hinged to the injection pressing assembly 3, and the other end is hinged to the eccentric part of the knob. When the knob is rotated, the first connecting rod drives the lifting member 2 to rise; the second connecting rod drives the injection pressing assembly 3 to move downward.

[0051] Reference Figures 2 to 7 The injection holder 1 has a rotation reference line 12 on its top, and the rotating cap 43 has a rotation scale line 431 on its peripheral wall. When the rotating cap 43 is driven to rotate, the angle of rotation of the positive threaded rod 41 driven by the rotating cap 43 and whether it has rotated a full circle (360 degrees) can be intuitively understood through the cooperation of the rotation reference line 12 and the rotation scale line 431, and then the injection volume can be calculated.

[0052] Reference Figures 2 to 10 The outer wall of the lifting member 2 is provided with a lifting reference line 23, and the outer wall of the injection bracket 1 is provided with a first height scale line 13. When the reverse threaded rod 42 drives the lifting member 2 to rise, the lifting reference line 23 and the first height scale line 13 can be used to visually determine the distance the lifting member 2 drives the syringe barrel 51 of the syringe 5 to rise. Similarly, the side wall of the sliding member 31 is provided with a moving reference line 311, and the side wall of the injection bracket 1 is provided with a second height scale line 14. When the forward threaded rod 41 drives the sliding member 31 to fall, the moving reference line 311 and the second height scale line 14 can be used to visually determine the distance the sliding member 31 drives the piston rod 52 to fall, thereby verifying the injection volume. That is, the rotating cap drives the forward threaded rod 41 and the reverse threaded rod 42 to rotate one revolution, the lifting member 2 can drive the syringe 51 and the injection needle 53 to rise by 1mm or 2mm, and the sliding member 31 drives the piston rod 52 to move down by 2mm or 4mm, thereby causing the injected stem cells or drugs to form a columnar body with a height of 1mm or 2mm.

[0053] Combination Figure 2 Reference Figures 5 to 6The lifting block 15 has a protrusion 151 integrally formed on the side near the lifting member 2. The lifting member 2 has a mating groove 25, the length of which is lateral. The protrusion 151 is inserted into the mating groove 25, and the horizontal drive member 6 passes through and is threadedly connected to the protrusion 151. The protrusion 151 is a rectangular block. Inserted into the mating groove 25, the upper and lower sides of the protrusion 151 abut against the upper and lower walls of the mating groove 25, forming a guide rail-like structure. This restricts the direction of movement of the lifting member 2, ensuring that the lifting member 2 drives the syringe 5 to move stably in the set direction, preventing deviation and improving the accuracy of the movement of the syringe 5 by the lifting member 2.

[0054] In this embodiment, the preferred horizontal drive component 6 is a threaded rod (thread not shown in the figure). The horizontal drive component 6 is inserted into the mating groove 25, and its axial direction is left-right, thus driving the lifting component 2 to move in the left-right direction. A bearing hole 26 is provided on the outer wall of the left side of the lifting component 2. The bearing hole 26 communicates with the mating groove 25 and penetrates the lifting component 2 in the left-right direction. Rotary bearings are interference-fitted and fixed to the left and right ends of the bearing hole 26 with glue. The horizontal drive component 6 is inserted into the bearing hole 26 and is inserted into the inner ring of the two rotary bearings, and is tightly fitted to the inner ring of the two rotary bearings, thereby enabling the horizontal drive component 6 to rotate relative to the lifting component 2.

[0055] Combination Figure 2 Reference Figures 5 to 6 One end of the horizontal drive component 6 protrudes from the bearing hole 26 and extends beyond the lifting component 2. A knob cap is fitted onto the end of the horizontal drive component 6 that extends beyond the lifting component 2. A set screw hole is formed on the outer wall of the knob cap, communicating with the interior of the knob cap. A set screw is threaded into the set screw hole, and the set screw abuts against the outer wall of the part of the horizontal drive component 6 that is inserted into the knob cap. Therefore, the knob cap can rotate synchronously with the horizontal drive component 6. By setting the knob cap, the outer diameter of the horizontal drive component 6 can be increased, making it easier for the operator to pinch the knob cap with two fingers to drive the horizontal drive component 6 to rotate.

[0056] Reference Figures 5 to 11 The lifting block 15 is provided with a horizontal reference line 152, and the lifting component 2 is provided with a horizontal scale line 24. During the process of driving the lifting component 2 to move left and right, the operator can intuitively understand the distance of the left and right movement of the lifting component 2 through the cooperation of the horizontal reference line 152 and the horizontal scale line 24, thereby improving the accuracy of the operation of the lifting component 2.

[0057] Combination Figure 1 Reference Figures 5 to 13Since the lifting member 2 is located on the front side of the injection bracket 1, a base 16 is fixedly provided at the bottom front side of the injection bracket 1, and the lifting member 2 is located on the top of the base 16. A through hole is provided at the top of the base 16, and a needle holder 17 is detachably inserted into the through hole. A sheath needle tube 18 is detachably inserted into the needle holder 17. The sheath needle tube 18 is suitable for being inserted into the nucleus before injection to form an injection cavity. The injection needle 53 is inserted into the sheath needle tube 18 and is clearance-fitted with the sheath needle tube 18.

[0058] The needle holder 17 has multiple positioning holes 171 spaced apart on the side near the lifting member 2. All positioning holes 171 penetrate the needle holder 17, and their arrangement direction is the same as the left-right movement direction of the lifting member 2. The needle tube 18 is designed to be tightly inserted into any one of the positioning holes 171 without shifting. The end of the needle tube 18 furthest from the lifting member 2 is located below the needle holder 17 for insertion into the nucleus. In this embodiment, three positioning holes 171 are preferably provided. The maximum outer diameter of the needle tube 18 is smaller than the diameter of the second insertion hole. Therefore, when the needle tube 18 needs to be removed after each injection, it can be easily pushed upwards out of the mounting hole 21.

[0059] Combination Figure 1 Reference Figures 5 to 13 The end of the sheath needle tube 18 furthest from the lifting member 2 is flat and has a rounded surface, thereby reducing the risk of injuring other cells or nerves during the insertion of the sheath needle tube 18 into the nucleus. After the sheath needle tube 18 forms a cavity within the nucleus, the injection needle 53 is then inserted into the sheath needle tube 18. The side wall of the injection needle 53 furthest from the syringe barrel 51 has an injection outlet 531, through which stem cells or drugs are suitable for being discharged from the syringe barrel 51. The end of the injection needle 53 furthest from the syringe barrel 51 is hemispherical to prevent the injection needle 53 from protruding from the sheath needle tube 18 after insertion and injuring a large number of other cells or nerves.

[0060] The injection support 1 is adapted to connect with the rotating structure on the surgical head frame. The injection support 1 can drive the injection needle 53 to rotate around the injection needle 53 as the rotation axis under the action of the rotating structure, which is used to adjust the orientation of the injection outlet 531. The surgical head frame is provided with a rotation angle reference line, and the front side of the base 16 is provided with a rotation angle scale line 162 that cooperates with the rotation angle reference line. According to the injection requirements, during injection, the base of stem cells or drugs needs to be directly inserted into the nucleus. Therefore, the injection outlet 531 needs to protrude from the needle tube 18. However, since the injection outlet 531 is located on the side wall of the injection needle 53, it will impact the nucleus at the beginning of the injection. If the injection port faces the side with thinner nucleus wall, it is easy to cause nucleus rupture. Therefore, the injection support 1 and the injection needle 53 can be rotated around the injection needle 53 as the rotation axis through the rotating structure on the surgical head frame. At the same time, with the rotation angle reference line and the rotation angle scale line 162, the rotation angle can be precisely controlled so that the injection opening faces the side with thicker nucleus wall, reducing the risk of nucleus rupture.

[0061] Since the injection outlet 531 is located on the side wall of the injection needle 53, during injection, the stem cells or drugs will impact the inner wall of the needle tube 18 under pressure, instead of directly impacting the nucleus. On the one hand, the needle tube 18 protects the nucleus, and on the other hand, it constrains the injected stem cells or drugs, allowing the stem cells or drugs to form a relatively compact and uniformly dense column.

[0062] Depending on the treatment plan, different inner diameters and diameters of the sheath needle 18 can be selected, resulting in different outer diameters of the injected columnar stem cells or drugs. Correspondingly, the ratio of the forward threaded rod 41 to the reverse threaded rod 42 can also be adjusted. The injection volume generated during the ascent of the syringe 51 and the injection volume generated during the descent of the sliding member 31 can be superimposed to increase the injection rate. Consequently, when the syringe 51 rises, the injected stem cells or drugs can fill the corresponding positions of the sheath needle 18, preventing loosening.

[0063] Reference Figure 13 The outer wall of the needle holder 17 has a limiting annular groove 172. A insertion groove is provided on one side of the outer wall of the base 16, communicating with a through hole. A limiting block 161 is inserted into the insertion groove, and the limiting block 161 is adapted to be inserted into the limiting annular groove 172 to limit the vertical movement of the needle holder 17, thus confining the needle holder 17 within the through hole. A bolt hole is provided on the outer wall of the base 16 away from the insertion groove, communicating with the through hole. A locking bolt is inserted into the bolt hole, and the locking bolt is threadedly connected to the limiting block 161. This prevents the limiting block 161 from moving within the insertion groove or disengaging from it, thereby improving the stability of the limiting block 161 locking the needle holder 17 within the limiting annular groove 172.

[0064] The outer wall of the needle holder 17 is integrally formed with a blocking ring 173. The outer diameter of the blocking ring 173 is larger than the diameter of the through hole. The blocking ring 173 is located below the limiting ring groove 172 and is spaced apart from the limiting ring groove 172. The needle holder 17 needs to be inserted into the through hole from the bottom of the base 16. When the blocking ring 173 abuts against the bottom of the base 16, the limiting block 161 is aligned with the limiting ring groove 172 so that the limiting block 161 can be inserted into the limiting ring groove 172, improving the accuracy of locking the needle holder 17. In this way, the needle holder 17 with a corresponding number or a specific distance between positioning holes 171 can be replaced according to the treatment situation to improve the injection accuracy in the corresponding treatment plan.

[0065] Combination Figure 1 Reference Figures 12 to 13 When the lifting member 2 moves left and right for adjustment, the syringe 5 needs to be removed and the needle tube 18 in the positioning hole 171 for injection needs to be removed. A new needle tube 18 is then inserted into the positioning hole 171 at the next injection point. After the lifting member 2 moves and is adjusted, a new syringe 5 is installed, and the injection needle 53 can be inserted into the needle tube 18 in the corresponding positioning hole 171.

[0066] The implementation principle of a stem cell injection structure in this application embodiment is as follows: During treatment, a small hole is first made at the site where stem cells or drugs need to be injected into the patient using a minimally invasive device. Then, the injection stent 1 is connected to the operating table or surgical head frame, and its position and angle are adjusted. Before injection, the syringe 5 is not installed, and a plugging needle is inserted into the sheath needle tube 18, making the sheath needle tube 18 a solid needle structure. Then, by operating the adjustment structure on the surgical head frame or operating table, the injection stent 1 drives the sheath needle tube 18 to puncture into the nucleus to be treated. Then, the plugging needle is removed, forming an injection cavity inside the sheath needle tube 18. Then, the syringe 51 containing stem cells or drugs is inserted into the mounting hole 21, and the injection needle 53 is inserted into the sheath needle tube 18. Then, the set screw 22 is tightened to fix the syringe 51. Then, the abutment plate 32 is adjusted so that the abutment plate 32 abuts against the piston rod 52 and the abutment plate 32 is locked.

[0067] During injection, the doctor rotates the cap 43, causing the forward threaded rod 41 and the reverse threaded rod 42 to rotate synchronously. The forward threaded rod 41 drives the sliding member 31 to move downward at a constant speed, driving the abutment plate 32 to push the piston rod 52 to move, so as to inject the stem cells or drugs in the syringe 51 at a constant speed. At the same time, the reverse threaded rod 42 drives the lifting member 2 to move the syringe 51 and the needle upward at a constant speed, forming an effect of injection and withdrawal at the same time, so that the injected stem cells or drugs can form a column with a relatively uniform density. During injection, the lifting baseline 23, in conjunction with the first height scale line 13, allows for a direct visual understanding of the upward distance of the syringe barrel 51 driven by the lifting component 2; the moving baseline 311, in conjunction with the second height scale line 14, allows for a direct visual understanding of the downward distance of the piston rod 52 driven by the injection pressing component 3; the rotating baseline 12, in conjunction with the rotating scale line 431, allows for a direct visual understanding of the rotation angle of the injection drive component 4, thereby converting the rotation angle of the cap 43 into the injection volume (for example, when the cap 43 rotates one revolution, the lifting component 2 drives the syringe barrel 51 and injection needle 53 to rise by 1 mm, thus forming a columnar body with a height of 1 mm). The combination of multiple sets of baselines and scale lines allows the operator to directly understand the movement distance of the syringe 5, thereby calculating the injection volume and improving the accuracy of the injection content. Since the sliding component 31 is threadedly connected to the forward threaded rod 41, and the lifting component 2 is threadedly connected to the reverse thread, the syringe 5 can remain stable and stop injection when the cap 43 is stopped rotating.

[0068] After the first injection, adjust the abutment plate 32 and remove the syringe 5 and the sheath needle tube 18 from the mounting hole 21. Then, turn the horizontal drive 6. Since the horizontal drive 6 is threadedly engaged with the protrusion 151, it will drive the lifting member 2 to move. During the movement of the lifting member 2, the operator can intuitively understand the distance the lifting member 2 moves by referring to the coordinates of the baseline and scale lines, thus improving the accuracy of the movement of the lifting member 2. After the position of the lifting member 2 is adjusted, insert the new sheath needle tube 18 and the plug needle from the mounting hole 21 into the corresponding positioning hole 171 to form a cavity in the corresponding nucleus. After removing the plug needle, insert the new syringe 5 into the mounting hole 21. The injection needle 53 will be inserted and pass through the corresponding sheath needle tube 18 into another nucleus. Finally, repeat the injection action.

[0069] Secondly, another embodiment of the present invention provides a neurosurgical head frame, including the stem cell injection structure of the first aspect.

[0070] Similarly, the components included in the "components," "mechanisms," and "devices" of this disclosure can also be flexibly combined. They can be modularly produced according to actual needs and assembled as an independent module; or they can be assembled separately to form a module in this device. The division of the above-mentioned components in this disclosure is only one embodiment for ease of reading and is not intended to limit the scope of protection of this disclosure. Any technical solution that includes the above-mentioned components and has the same function should be understood as an equivalent technical solution of this disclosure.

[0071] In the description of this disclosure, it should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," and "circumferential" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this disclosure and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this disclosure.

[0072] Furthermore, the terms "first," "second," etc., are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined with "first," "second," etc., may explicitly or implicitly include at least one of that feature. In the description of this disclosure, "a plurality of" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0073] In this disclosure, unless otherwise expressly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this disclosure according to the specific circumstances.

[0074] In this disclosure, unless otherwise expressly specified and limited, "above" or "below" the second feature can mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0075] It should be noted that when a component is referred to as "fixed to," "set on," "fixed to," or "mounted on" another component, it can be directly on the other component or there may be an intervening component. When a component is considered to be "connected to another component," it can be directly connected to the other component or there may be an intervening component. Furthermore, when a component is considered to be "fixedly connected" to another component, the connection can be detachable or non-detachable, such as through socketing, snap-fitting, integral molding, welding, etc., which are achievable in conventional technologies and will not be elaborated upon here.

[0076] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0077] The above embodiments are merely illustrative of several implementation methods of this disclosure, and their descriptions are relatively specific and detailed. However, they should not be construed as limiting the scope of the invention patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the inventive concept of this disclosure, and these modifications and improvements all fall within the protection scope of this disclosure.

Claims

1. A stem cell injection structure, characterized by: The utility model provides an injection device, which comprises an injection support (1), a lifting piece (2), an injection pressing assembly (3), an injection driving assembly (4) and an injector (5), the lifting piece (2) and the injection pressing assembly (3) are slidably connected with the injection support (1); the injector (5) comprises a syringe (51), a piston rod (52) and an injection needle (53), the piston rod (52) is slidably connected with the syringe (51), the syringe (51) is detachably connected with the lifting piece (2) and moves synchronously, the injection pressing assembly (3) is in abutment with the top of the piston rod (52), and the injection needle (53) is connected with one end of the syringe (51) away from the piston rod (52); the injection driving assembly (4) is rotationally connected with the injection support (1), and the lifting piece (2) and the injection pressing assembly (3) are movably connected with the injection driving assembly (4); during injection, after the injection driving assembly (4) is driven to rotate, the lifting piece (2) drives the syringe (51) to move upwards relative to the injection support (1), and at the same time, the injection pressing assembly (3) drives the piston rod (52) to move downwards relative to the injection support (1); a side wall of one end of the injection needle (53) away from the syringe (51) is provided with an injection outlet (531), stem cells or drugs are adapted to be discharged from the syringe (51) through the injection outlet (531); the injection support (1) is adapted to be rotationally connected with a surgical head frame with the injection needle (53) as a rotation axis, so as to adjust the orientation of the injection outlet (531); the injection driving assembly (4) comprises a forward threaded rod (41) and a reverse threaded rod (42), the forward threaded rod (41) and the reverse threaded rod (42) are connected and synchronously rotated, the forward threaded rod (41) and the reverse threaded rod (42) are rotationally connected with the injection support (1), a lifting block (15) is sleeved and threadedly connected on the reverse threaded rod (42), the lifting piece (2) is slidably connected with the lifting block (15), and after the reverse threaded rod (42) is rotated, the lifting block (15) will drive the lifting piece (2) to synchronously lift and fall; the injection pressing assembly (3) is threadedly connected with the forward threaded rod (41), so as to drive the injection pressing assembly (3) to move relative to the injection support (1); a lug (151) is fixedly arranged on one side of the lifting block (15) close to the lifting piece (2), a matching long groove (25) is formed in the lifting piece (2), and the lug (151) is inserted into the matching long groove (25); a horizontal driving piece (6) is rotationally arranged on the lifting piece (2), the horizontal driving piece (6) penetrates through the lug (151) and is threadedly connected with the lug (151), one end of the horizontal driving piece (6) is in a suspended state and penetrates through the lifting piece (2), and when the horizontal driving piece (6) is driven to rotate, the lifting piece (2) will be driven to move along the horizontal direction relative to the injection support (1) with the syringe (51).

2. The stem cell injection structure according to claim 1, characterized by: The surgical headstock is provided with a rotation angle reference line, and the injection support (1) is provided with a rotation angle scale line (162) matched with the rotation angle reference line.

3. The stem cell injection structure according to claim 1, characterized by: The injection support (1) is detachably connected with a needle tube seat (17), the needle tube seat (17) is located below the lifting piece (2), the needle tube seat (17) is detachably connected with a sheathed needle tube (18), the sheathed needle tube (18) is suitable for being inserted into a nuclear group to form an injection cavity, the injection needle (53) is inserted into the sheathed needle tube (18), and the injection outlet (531) protrudes from the sheathed needle tube (18), and the injection needle (53) is in clearance fit with the sheathed needle tube (18).

4. The stem cell injection structure according to claim 3, characterized by: The needle tube seat (17) is provided with a plurality of positioning holes (171) on one side close to the lifting piece (2), the plurality of positioning holes (171) all penetrate through the needle tube seat (17), the sheathed needle tube (18) is suitable for being inserted into any one of the positioning holes (171), and one end of the sheathed needle tube (18) away from the lifting piece (2) is located below the needle tube seat (17).

5. The stem cell injection structure according to any one of claims 1 to 4, wherein: The pitch of the forward threaded rod (41) is greater than or equal to the pitch of the reverse threaded rod (42).

6. The stem cell injection structure according to claim 5, characterized by: The injection pressing assembly (3) comprises a sliding piece (31) and an abutting plate (32), the sliding piece (31) is in threaded connection with the forward threaded rod (41), and the abutting plate (32) is in sliding connection with the sliding piece (31) to adapt to the piston rod (52) extending in different lengths; when the forward threaded rod (41) is driven to rotate, the forward threaded rod (41) drives the sliding piece (31) to move the abutting plate (32) and the piston rod (52).

7. The stem cell injection structure according to claim 6, characterized by: The injection pressing assembly (3) further comprises an extension rod (33), the extension rod (33) is connected with the sliding piece (31) and moves synchronously, the abutting plate (32) is sleeved and directionally slides on the extension rod (33), the abutting plate (32) is provided with a locking piece, and the locking piece is suitable for locking or unlocking the movement of the abutting plate (32).

8. A neurosurgical operating headrest, characterized by A stem cell injection structure as claimed in any one of claims 1-7. A stem cell injection structure as claimed in any one of claims 1-7.

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