BFS Filling Ampoule Quality Inspection System and Method

Abstract

This invention discloses a quality inspection system and method for BFS-filled ampoules, relating to the field of ampoule quality inspection technology. It includes: a scanning analysis module: setting up at least four scanning modules based on the position of the ampoules in the array to acquire bottle information and drug filling information, obtaining bottle information items and drug filling information items; and a control adjustment module: acquiring control wavelength information based on the bottle information items and drug filling information items through data acquisition. This invention, by setting up multiple scanning modules to acquire the bottle information and drug filling information of the ampoules respectively, and setting corresponding scanning wavelengths according to the bottle information and drug filling information, respectively acquires the resistance information of the drug filling information items in the bottle spectrum and the resistance information of the drug filling information items in the bottle spectrum. The wavelength with the highest resistance strength is used as the control adjustment wavelength to prevent interference between the two wavelengths, thus improving the accuracy of the detection results.

Description

TECHNICAL FIELD

[0001] The present application relates to ampoule quality detection technical field, specifically to BFS filling row ampoule quality detection system and method. BACKGROUND

[0002] BFS filling refers to a continuous blow, filling and sealing integrated aseptic production process, which is widely used in high requirement liquid preparation production, row ampoule refers to a plurality of ampoules in a row, after BFS filling, some ampoules have some quality defects, for example, different drug loading in each bottle, at this time, the ampoules with differences need to be removed, otherwise it will affect the dose accuracy and appearance of the medicine, and some ampoules have collapse, affecting the appearance, or have irregular edges, common ampoule quality detection includes volume and filling amount detection, online monitoring is realized through torch light, weight sensor, ultrasonic wave, or sampling and weighing of each batch to calculate the filling amount distribution.

[0003] The patent with publication number CN112577967A discloses a method for detecting the appearance quality of the head of a medical ampoule, which is based on the arc features at the top of the bottle head and the transition features between the arc and the side contour. When there is no concave or convex phenomenon at the top of the bottle head or at the transition between the arc and the side contour, the appearance of the head of the ampoule is qualified. Otherwise, the appearance of the head of the ampoule is unqualified. The method for detecting the appearance quality of the head of a medical ampoule greatly improves the speed, accuracy and reliability of automatic detection of defects in the appearance of the head of the ampoule, which not only meets the requirements of batch detection, but also saves manpower and reduces production costs.

[0004] The above-mentioned and similar technical solutions perform real-time image acquisition and analysis on ampoules, extract the bottle contour, liquid level height and sealing shape features by using deep learning algorithm, and automatically determine the defect type in combination with the preset quality standard. However, the conventional method for detecting the drug loading is to compare the detected liquid level height with the set liquid level height, and determine that it is unqualified when a difference is detected in the liquid level height. However, due to the difference in the internal shape of the ampoule, even if the liquid level position is inconsistent, the drug loading may be consistent. For example, there is a bulge inside the bottle, which causes the liquid level to rise. At this time, although the detected liquid level height is inconsistent with the set liquid level height, the liquid capacity is consistent, which may cause misjudgment. SUMMARY

[0005] The present application aims to provide a BFS filling row ampoule quality detection system and method to solve the problems raised in the background.

[0006] To achieve the above-mentioned purpose, the present application provides the following technical solution: a BFS filling row ampoule quality detection system, comprising:

[0007] The scanning analysis module: set the scanning module, set at least four groups of scanning modules based on the position of the row of ampoules, obtain the bottle body information and the charge information of the row of ampoules, and obtain the bottle body information item and the charge information item;

[0008] The adjustment comparison module: based on the bottle body information item and the charge information item, the comparison wavelength information is obtained by data acquisition, and then the first adjustment wavelength and the second adjustment wavelength are obtained, the wavelength of the scanning module is adjusted based on the first adjustment wavelength and the second adjustment wavelength, and the wavelength adjustment item is obtained;

[0009] The path analysis module: obtain the moving path of the row of ampoules, obtain the real-time path item, perform scanning path analysis based on the real-time path item, obtain the path analysis item, and scan the target row of ampoules through the scanning module based on the path analysis item and the wavelength adjustment item, and obtain the bottle scanning item and the charge scanning item respectively;

[0010] The reconstruction calculation module: based on the bottle scanning item and the charge scanning item, the volume reconstruction is performed, and then the bottle reconstruction item and the charge reconstruction item are obtained, the preliminary detection is performed based on the bottle reconstruction item, the first detection threshold is set, the unqualified products are screened out, the first screening item is obtained, the secondary detection is performed based on the charge reconstruction item, the second detection threshold is set, the unqualified products are screened out, the second screening item is obtained, and the double quality detection of the row of ampoules is performed based on the combination of the first screening item and the second screening item, while avoiding the quality misjudgment caused by the internal shape of the ampoule.

[0011] Further, the scanning module includes an infrared scanning module, and the method for obtaining the bottle body information item and the charge information item includes:

[0012] Obtain the position information of the row of ampoules, obtain the target position item, set the position limit value based on the target position item, the position limit value is a fixed distance value, and obtain the set distance item;

[0013] Based on the set distance item, set at least four scanning points with the target position item as the center point, install the infrared scanning module based on the scanning points, and obtain the scanning installation item;

[0014] Based on the infrared scanning module, set the first wavelength library and the second wavelength library, the first wavelength library matches the bottle body information, and the second wavelength library matches the charge information, set the resolution based on the first wavelength library, set the optical path based on the second wavelength library, and separately scan the bottle body information and the charge information of the row of ampoules, obtain the absorption fingerprint of the infrared module, perform fingerprint matching, and obtain the bottle body information item and the charge information item.

[0015] Further, the scanning module further includes a multi-wavelength scanning module, and the method for obtaining the first adjustment wavelength and the second adjustment wavelength includes:

[0016] Based on the bottle information item and the charging information item, the spectrum feature matching absorption peak data is obtained by data acquisition, and the bottle spectrum set and the medicine spectrum set are obtained;

[0017] Based on the bottle spectrum set and the medicine spectrum set, the resistance information of the charging information item in the bottle spectrum set and the resistance information of the bottle information item in the medicine spectrum set are obtained, and the bottle sorting item and the medicine sorting item are sorted according to the resistance intensity from high to low, and the bottle sorting item and the medicine sorting item are obtained.

[0018] The first position of the bottle sorting item and the medicine sorting item is obtained as a control adjustment wavelength, and then the first adjustment wavelength and the second adjustment wavelength are obtained.

[0019] Further, the wavelength adjustment item acquisition method comprises:

[0020] The scanning threshold and the interval threshold are set, the scanning threshold and the interval threshold are fixed time values, the first adjustment wavelength and the second adjustment wavelength are limited in time based on the scanning threshold, and the first adjustment wavelength and the second adjustment wavelength are alternately limited based on the interval threshold;

[0021] The scanning round is set, the scanning round is a fixed number of times, the scanning number is limited based on the scanning round, and then the wavelength adjustment item is obtained.

[0022] Further, the interval threshold setting method comprises:

[0023] Based on the first adjustment wavelength and the second adjustment wavelength, the action data of the first adjustment wavelength and the second adjustment wavelength and the bottle information item and the charging information item is obtained by data acquisition, including influence attenuation data, and the first wavelength attenuation item and the second wavelength attenuation item are obtained;

[0024] The first wavelength attenuation item is used as the interval of the first adjustment wavelength, the first interval value is obtained, the second wavelength attenuation item is used as the interval of the second adjustment wavelength, the second interval value is obtained, and the interval threshold is obtained by combining the first interval value and the second interval value.

[0025] Further, the path analysis item acquisition method comprises:

[0026] Based on the real-time path item, the top point information and the bottom point information of the target linear array ampoule are obtained, the marked top point item and the marked bottom point item are obtained, and the marked path is obtained based on the marked top point item and the marked bottom point item.

[0027] The analysis time is set, the scanning path analysis is performed based on the combination of the analysis time and the marked path, and then the path analysis item is obtained.

[0028] Further, the first detection threshold is an appearance threshold, including a contour threshold and a sealing threshold, and the obtaining method of the first screening item comprises:

[0029] The detection limit values are set based on the contour threshold and the sealing threshold, the contour offset limit value and the sealing burr limit value are set, and the contour setting item and the sealing setting item are obtained;

[0030] The target BFS filling row ampoule is preliminarily quality screened based on the contour setting item and the sealing setting item, the target BFS filling row ampoule exceeding the contour setting item and the sealing setting item is rejected, and the first screening item is obtained.

[0031] Further, the second detection threshold is a charge amount threshold, and the obtaining method of the second screening item comprises:

[0032] The slice is performed based on the charge reconstruction item, the minimum slice value is set, the slice is performed on the charge reconstruction item based on the minimum slice value, and the charge slice item is obtained;

[0033] The capacity calculation is performed based on the charge slice item, and then the charge capacity calculation item is obtained, the target BFS filling row ampoule not meeting the charge amount threshold is rejected according to the comparison relationship between the charge capacity calculation item and the charge amount threshold, and the second screening item is obtained.

[0034] The BFS filling row ampoule quality detection method uses the BFS filling row ampoule quality detection system, and comprises:

[0035] The scanning module is set, at least four groups of scanning modules are set based on the position of the row ampoule, and the bottle body information and the charge information of the row ampoule are obtained;

[0036] The control wavelength information is obtained based on the bottle body information and the charge information, and then the first adjustment wavelength and the second adjustment wavelength are obtained, and the wavelength of the scanning module is controlled and adjusted based on the first adjustment wavelength and the second adjustment wavelength;

[0037] The moving path of the row ampoule is obtained, the real-time path item is obtained, the scanning path analysis is performed based on the real-time path item, the path analysis item is obtained, the target row ampoule is scanned by the scanning module, and the bottle body scanning item and the charge scanning item are obtained respectively;

[0038] The volume reconstruction is performed based on the bottle body scanning item and the charge scanning item, and then the bottle body reconstruction item and the charge reconstruction item are obtained, the preliminary detection is performed based on the bottle body reconstruction item, the unqualified product is screened out, the first screening item is obtained, the secondary detection is performed based on the charge reconstruction item, the unqualified product is screened out, the second screening item is obtained, and the double quality detection of the row ampoule is performed based on the combination of the first screening item and the second screening item.

[0039] Compared with the prior art, the application has the beneficial effects that:

[0040] The BFS filling row ampoule quality detection system and method, by setting multiple groups of scanning modules to respectively acquire the bottle body information and the charging information of the ampoule, and setting the corresponding scanning wavelength according to the bottle body information and the charging information, respectively acquiring the resistance information of the bottle body spectrum concentrated charging information item and the resistance information of the medicine spectrum concentrated bottle body information item, taking the highest resistance intensity as the contrast adjustment wavelength, preventing the mutual interference of the two wavelengths, improving the accuracy of the detection result, and according to the contrast adjustment wavelength, respectively performing bottle body reconstruction and charging reconstruction on the target ampoule, performing first re-detection according to the bottle body reconstruction result, and performing second re-detection according to the charging reconstruction result, screening out unqualified products, while performing double quality detection, avoiding quality misjudgment caused by the internal shape of the ampoule. BRIEF DESCRIPTION OF DRAWINGS

[0041] Figure 1 It is a whole flow structure schematic diagram of the application;

[0042] Figure 2 It is a scanning installation item acquisition flow schematic diagram of the application;

[0043] Figure 3 It is a bottle body information item and charging information item acquisition flow schematic diagram of the application;

[0044] Figure 4 It is a bottle body sorting item and charging sorting item acquisition flow schematic diagram of the application. DETAILED DESCRIPTION

[0045] The technical solutions in the embodiments of the application will be clearly and completely described below with reference to the drawings in the embodiments of the application. Obviously, the described embodiments are only part of the embodiments of the application, rather than all the embodiments of the application. Based on the embodiments in the application, all other embodiments obtained by those of ordinary skill in the art without creative labor fall within the protection scope of the application.

[0046] The ampoule may have consistent liquid capacity even if the liquid level position is different due to the diversity of the internal shape of the ampoule. For example, when there is a bulge or other irregular structure inside the ampoule, the liquid level may be raised due to the volume being squeezed by the liquid. In this case, although the detected liquid level height does not match the set standard value, the liquid capacity in the bottle does not change and still meets the quality requirements. If a simple judgment is made according to the liquid level height, it will lead to a misjudgment, and the qualified product will be incorrectly judged as unqualified, thereby increasing unnecessary production costs and resource waste. This misjudgment not only affects production efficiency, but more importantly, it may cover up the real quality problem. If the actual loading capacity of the ampoule is insufficient, but the liquid level height is close to the standard due to the particularity of the internal structure of the bottle, it may be incorrectly judged as qualified and then flow into the market, which poses a potential risk to the safety of patient medication. The technical solution provided by the present application sets multiple scanning modules to obtain the bottle information and the loading information of the ampoule, sets the corresponding scanning wavelength according to the bottle information and the loading information, respectively obtains the resistance information of the bottle spectrum concentrated loading information item and the resistance information of the loading spectrum concentrated bottle information item, takes the highest resistance as the control adjustment wavelength to prevent the wavelengths from interfering with each other, improves the accuracy of the detection result, and according to the control adjustment wavelength, respectively reconstructs the bottle and the loading of the target ampoule, performs first re-detection according to the bottle reconstruction result, and performs second re-detection according to the loading reconstruction result, to screen out unqualified products. At the same time of double quality detection, the quality misjudgment caused by the internal shape of the ampoule is avoided, such as Figure 1 As shown, the technical solution comprises a scanning analysis module, an adjustment control module, a path analysis module, and a reconstruction calculation module.

[0047] Scanning analysis module: Set the scanning module, set at least four groups of scanning modules based on the position of the row of ampoules, obtain the bottle information and the loading information of the row of ampoules, and obtain the bottle information item and the loading information item.

[0048] It should be noted that, as Figures 2-3The scanning module comprises an infrared scanning module. The method for obtaining the bottle body information item and the drug information item comprises the following steps: obtaining position information of the aligned ampoule bottles to obtain a target position item; setting a position limit value based on the target position item, the position limit value being a fixed distance value to obtain a set distance item; based on the set distance item, setting at least four scanning points with the target position item as a center point, installing the infrared scanning module based on the scanning points to obtain a scanning installation item; based on the infrared scanning module, setting a first wavelength library and a second wavelength library, the first wavelength library matching the bottle body information and the second wavelength library matching the drug information, setting a resolution based on the first wavelength library and setting an optical path based on the second wavelength library, separately scanning the bottle body information and the drug information of the aligned ampoule bottles to obtain an absorption fingerprint of the infrared module, performing fingerprint matching to obtain the bottle body information item and the drug information item.

[0049] Specifically, when the aligned ampoule bottles are subjected to quality detection, the aligned ampoule bottles are conveyed to a detection point through a production line. At this time, the position information of the aligned ampoule bottles is obtained, a position limit value is set, the position limit value is 50 cm, six scanning points are set with the position of the aligned ampoule bottles as a center point, the six scanning points are located at the upper front surface, the upper back surface, the left side of the front surface, the right side of the front surface, the left side of the back surface and the right side of the back surface of the aligned ampoule bottles respectively, a total of six scanning points are provided, the infrared scanning module is installed respectively, the first wavelength library and the resolution are set simultaneously, the scanning times are set according to the resolution, the bottle body information of the aligned ampoule bottles is scanned, the second wavelength library and the optical path are set, the drug information is scanned, the absorption fingerprint of the infrared module is obtained to perform fingerprint matching, and the bottle body information item and the drug information item are obtained.

[0050] In the specific implementation process, the infrared scanning of a certain ampoule bottle is needed. First, the first wavelength library range is set as 4000-650 cm -1 , the resolution is set as 4 cm -1 , the scanning times are 32 times, and the scanning result is 2950 cm -1 C-H stretching vibration, 1455 cm -1 CH2 bending vibration, 1375 cm -1 CH3 symmetric deformation, the conclusion is that the bottle body material is a PP copolymer, the second wavelength library range is set as 900-1700 nm, the optical path is 0.3 mm, the absorption peak characteristics obtained are that the carboxylate first-order frequency is 1550-1600 nm and the acetylamino C=O second-order frequency is 1690 nm, and the analysis result is that the drug information is glass sodium hyaluronate eye drops.

[0051] The adjusting control module: based on the bottle information item and the drug information item, the control wavelength information is obtained by data acquisition, and then the first adjusting wavelength and the second adjusting wavelength are obtained, and the wavelength of the scanning module is adjusted based on the first adjusting wavelength and the second adjusting wavelength, and the wavelength adjusting item is obtained.

[0052] It should be noted that the scanning module also includes a multi-wavelength scanning module, and the method for obtaining the first adjusting wavelength and the second adjusting wavelength includes: based on the bottle information item and the drug information item, the spectral feature matching absorption peak data is obtained by data acquisition, and the bottle spectrum set and the drug spectrum set are obtained; based on the bottle spectrum set and the drug spectrum set, the resistance information of the drug information item in the bottle spectrum set and the resistance information of the bottle information item in the drug spectrum set are obtained respectively and sorted according to the resistance intensity, and the bottle sorting item and the drug sorting item are obtained; the first position of the bottle sorting item and the drug sorting item is obtained as the control adjusting wavelength, and then the first adjusting wavelength and the second adjusting wavelength are obtained.

[0053] Specifically, after obtaining the specific bottle information item and the drug information item, since the scanning module also includes a multi-wavelength scanning module at this time, and the spectral feature matching absorption peak data of different bottle information items and drug information items is different, the spectral information most matched with the bottle information item and the drug information item is obtained by big data acquisition, and the bottle spectrum set and the drug spectrum set are obtained. The number of bottle spectrum set and drug spectrum set may not be more than one, and individual spectrum may interfere with each other, so the resistance information of the drug information item in the bottle spectrum set and the resistance information of the bottle information item in the drug spectrum set are obtained respectively, and the highest resistance intensity is taken as the control adjusting wavelength, and then the first adjusting wavelength and the second adjusting wavelength are obtained.

[0054] In the specific implementation process, as shown in Figure 4 The material of the side-by-side ampoule is A material, and the filling drug is B drug, so the bottle information item is A and the drug information item is B. The spectral information matched with A is 1, 2 and 3, and the spectral information matched with B is a, b, c and d, so the bottle spectrum set is (1, 2, 3) and the drug spectrum set is (a, b, c, d). At this time, among 1, 2 and 3, the interference intensity of B is 2>1>3, and the resistance intensity is sorted according to the order, so the bottle sorting item is 3, 1 and 2. Among a, b, c and d, the interference intensity of A is a>c>d>b, and the resistance intensity is sorted according to the order, so the drug sorting item is b, d, c and a. Therefore, the highest resistance intensity is selected as the control adjusting wavelength, and then the first adjusting wavelength and the second adjusting wavelength are obtained, the first adjusting wavelength is 3, and the second adjusting wavelength is b.

[0055] It should be noted that the wavelength adjustment item acquisition method comprises: setting a scanning threshold and an interval threshold, both of which are fixed time values, limiting the duration of the first adjustment wavelength and the second adjustment wavelength based on the scanning threshold, and limiting the alternation of the first adjustment wavelength and the second adjustment wavelength based on the interval threshold; set the scanning rounds, which is a fixed number of times, limit the number of scans based on the scanning rounds, and then obtain the wavelength adjustment item.

[0056] Specifically, the set scanning rounds are 5, that is, after the first adjustment wavelength completes scanning, the second adjustment wavelength is scanned after the interval threshold, and after the scanning is completed, it is completed in one round, and a total of five rounds are scanned.

[0057] It should be noted that the interval threshold setting method comprises: based on the first adjustment wavelength and the second adjustment wavelength, the action data of the first adjustment wavelength and the second adjustment wavelength with the bottle information item and the charge information item is obtained based on the data acquisition method, including the influence attenuation data, to obtain the first wavelength attenuation item and the second wavelength attenuation item; the first wavelength attenuation item is used as the interval of the first adjustment wavelength to obtain the first interval value, and the second wavelength attenuation item is used as the interval of the second adjustment wavelength to obtain the second interval value, and the first interval value and the second interval value are combined to obtain the interval threshold.

[0058] Specifically, after the first adjustment wavelength and the second adjustment wavelength are scanned respectively, due to the influence of the first adjustment wavelength and the second adjustment wavelength, a certain influence residue will be caused to the bottle information item and the charge information item. At this time, if the influence cannot be attenuated to a certain extent, it will interfere with the scanning again, so the interval corresponding to the first adjustment wavelength and the second adjustment wavelength is set according to the influence attenuation data of the bottle information item and the charge information item under the influence of the first adjustment wavelength and the second adjustment wavelength.

[0059] Path analysis module: obtain the moving path of the row ampoule, obtain the real-time path item, perform scanning path analysis based on the real-time path item, obtain the path analysis item, and based on the path analysis item and the wavelength adjustment item, scan the target row ampoule through the scanning module, and obtain the bottle scanning item and the charge scanning item respectively.

[0060] It should be noted that the path analysis item acquisition method comprises: based on the real-time path item, obtaining the vertex information and the bottom point information of the target row ampoule, obtaining the marked vertex item and the marked bottom point item, and based on the marked vertex item and the marked bottom point item, obtaining the marked path; set the analysis time, combine the analysis time and the marked path to perform scanning path analysis, and then obtain the path analysis item.

[0061] Specifically, after the top point information and the bottom point information of the target side-by-side ampoule are acquired, the line connecting the top point and the bottom point is taken as a marking path, the marking path is taken as the path of the movement of the scanning module, and the set analysis time is taken as the time limit for the movement of the scanning path.

[0062] The reconstruction calculation module: based on the bottle scanning item and the charge scanning item, the volume is reconstructed to obtain the bottle reconstruction item and the charge reconstruction item, based on the bottle reconstruction item, the preliminary detection is performed, the first detection threshold is set, the unqualified products are screened out to obtain the first screening item, based on the charge reconstruction item, the secondary detection is performed, the second detection threshold is set, the unqualified products are screened out to obtain the second screening item.

[0063] It should be noted that based on the combination of the first screening item and the second screening item, the double quality detection of the side-by-side ampoule is performed, and the quality misjudgment caused by the internal shape of the ampoule is avoided. The first detection threshold is the appearance threshold, including the contour threshold and the sealing threshold. The acquisition method of the first screening item includes: based on the contour threshold and the sealing threshold, the detection limit value is set, the contour offset limit value and the sealing burr limit value are set, the contour setting item and the sealing setting item are obtained; based on the contour setting item and the sealing setting item, the target side-by-side ampoule is preliminarily screened for quality, the target side-by-side ampoule exceeding the contour setting item and the sealing setting item is rejected, and the first screening item is obtained.

[0064] Specifically, the contour threshold and the sealing threshold include the maximum defect area of the coloring point, the distance of the point to the horizontal line, and the maximum defect area of the bottle mouth burr. For example, in the quality detection process of a certain side-by-side ampoule, the maximum defect area of the coloring point is allowed to be 300 μm², and the maximum value of the distance of the point to the horizontal line is different for different edges. Therefore, by setting the contour threshold and the sealing threshold, the target side-by-side ampoule is preliminarily screened for quality, the target side-by-side ampoule exceeding the contour setting item and the sealing setting item is rejected, and the first screening item is obtained.

[0065] It should be noted that the second detection threshold is the charge amount threshold, and the acquisition method of the second screening item includes: based on the charge reconstruction item, the slice is set, the minimum slice value is set, the charge reconstruction item is sliced based on the minimum slice value, and the charge slice item is obtained; based on the charge slice item, the capacity calculation is performed, and the charge capacity calculation item is obtained. According to the comparison relationship between the charge capacity calculation item and the charge amount threshold, the target side-by-side ampoule not meeting the charge amount threshold is rejected, and the second screening item is obtained.

[0066] Specifically, the set minimum slice value is 10 pm, the obtained charge reconstruction item is sliced, the area information of each slice is calculated, the volume of the charge reconstruction item is finally calculated, the target aligned ampoule that does not meet the set charge threshold is removed according to the set charge threshold, and the second screening item is obtained.

[0067] In the specific implementation process, a 2ml ampoule is analyzed by slicing, the set charge threshold is ≤±1.5%, the outer diameter of the ampoule is 12mm, the height is 40mm, according to the set minimum slice value of 10pm, and part of the slice calculation results are shown in Table 1:

[0068] Table 1

[0069]

[0070] The calculation result is 2020.5pl, the error is +1.025%, and it meets the charge threshold of ≤±1.5%.

[0071] The BFS filling aligned ampoule quality detection method uses the BFS filling aligned ampoule quality detection system described above, which includes: a set scanning module, at least four sets of scanning modules are set based on the position of the aligned ampoule, the bottle body information and the charge information of the aligned ampoule are obtained; the control wavelength information is obtained based on the bottle body information and the charge information, and then the first adjustment wavelength and the second adjustment wavelength are obtained, and the wavelength of the scanning module is adjusted based on the first adjustment wavelength and the second adjustment wavelength; the moving path of the aligned ampoule is obtained, the real-time path item is obtained, the scanning path analysis is carried out based on the real-time path item, the path analysis item is obtained, the target aligned ampoule is scanned by the scanning module, and the bottle body scanning item and the charge scanning item are obtained; volume reconstruction is carried out based on the bottle body scanning item and the charge scanning item, and then the bottle body reconstruction item and the charge reconstruction item are obtained, preliminary detection is carried out based on the bottle body reconstruction item, unqualified products are screened out, the first screening item is obtained, secondary detection is carried out based on the charge reconstruction item, unqualified products are screened out, the second screening item is obtained, and double quality detection of the aligned ampoule is carried out based on the combination of the first screening item and the second screening item.

[0072] Although the embodiments of the present application have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and variations can be made to the embodiments without departing from the principles and spirits of the present application, and the scope of the present application is defined by the appended embodiments and their equivalents.

Claims

1. A quality detection system for BFS filling row ampoules, comprising: a scanning analysis module: setting a scanning module, based on the position of the row ampoules, setting at least four groups of scanning modules, obtaining the bottle information and the charge information of the row ampoules, obtaining the bottle information item and the charge information item; characterized in that it further comprises: an adjustment comparison module: based on the bottle information item and the charge information item, obtaining the comparison wavelength information through data acquisition, and then obtaining the first adjustment wavelength and the second adjustment wavelength, comparing and adjusting the wavelength of the scanning module based on the first adjustment wavelength and the second adjustment wavelength, and obtaining the wavelength adjustment item; a path analysis module: obtaining the moving path of the row ampoules, obtaining the real-time path item, performing scanning path analysis based on the real-time path item, obtaining the path analysis item, and based on the path analysis item and the wavelength adjustment item, scanning the target row ampoules through the scanning module, and obtaining the bottle scanning item and the charge scanning item respectively; a reconstruction calculation module: based on the bottle scanning item and the charge scanning item, volume reconstruction is performed, and then the bottle reconstruction item and the charge reconstruction item are obtained, preliminary detection is performed based on the bottle reconstruction item, a first detection threshold is set, unqualified products are screened out, a first screening item is obtained, secondary detection is performed based on the charge reconstruction item, a second detection threshold is set, unqualified products are screened out, a second screening item is obtained, and based on the combination of the first screening item and the second screening item, double quality detection of the row ampoules is performed, while avoiding quality misjudgment caused by the internal shape of the ampoule; the second detection threshold is a charge amount threshold, and the method for obtaining the second screening item comprises: based on the charge reconstruction item, slicing is performed, a minimum slice value is set, the charge reconstruction item is sliced based on the minimum slice value, and the charge slice item is obtained; based on the charge slice item, capacity calculation is performed, and then the charge capacity calculation item is obtained, and based on the comparison relationship between the charge capacity calculation item and the charge amount threshold, the target row ampoule that does not meet the charge amount threshold is removed, and the second screening item is obtained.

2. The BFS filled side-by-side ampoule quality detection system of claim 1, wherein: The scanning module comprises an infrared scanning module, and the method for obtaining the bottle information item and the charge information item comprises: obtaining the position information of the row ampoules, obtaining the target position item, setting a position limit value based on the target position item, the position limit value being a fixed distance value, and obtaining the set distance item; based on the set distance item, setting at least four scanning points with the target position item as the center point, installing the infrared scanning module based on the scanning points, and obtaining the scanning installation item; based on the infrared scanning module, setting a first wavelength library and a second wavelength library, the first wavelength library matching the bottle information, and the second wavelength library matching the charge information, setting a resolution based on the first wavelength library, setting an optical path based on the second wavelength library, and separately scanning the bottle information and the charge information of the row ampoules, obtaining the absorption fingerprint of the infrared module, performing fingerprint matching, and obtaining the bottle information item and the charge information item.

3. The BFS filled side-by-side ampoule quality detection system of claim 1, wherein: The scanning module further comprises a multi-wavelength scanning module, and the method for obtaining the first adjustment wavelength and the second adjustment wavelength comprises: based on the bottle information item and the charge information item, respectively obtaining the spectral feature matching absorption peak data through data acquisition, obtaining the bottle spectrum set and the drug spectrum set; Based on the bottle spectrum set and the drug spectrum set, resistance information of the bottle information item in the bottle spectrum set and resistance information of the drug information item in the drug spectrum set are obtained respectively and sorted according to the resistance intensity, to obtain the bottle sorting item and the drug sorting item; The first and second adjustment wavelengths are obtained by taking the first and second sorting items as the control adjustment wavelength respectively.

4. The BFS filled side-by-side ampoule quality detection system of claim 1, wherein: The wavelength adjustment item includes: The scanning threshold and the interval threshold are set, both of which are fixed time values. The first and second adjustment wavelengths are limited in time based on the scanning threshold, and the first and second adjustment wavelengths are alternately limited based on the interval threshold; The scanning round is set, which is a fixed number of times. The scanning number is limited based on the scanning round, and the wavelength adjustment item is obtained.

5. The BFS filled side-by-side ampoule quality detection system of claim 4, wherein: The interval threshold includes: Based on the first and second adjustment wavelengths, the first and second adjustment wavelengths are obtained based on the data acquisition method, and the action data of the bottle information item and the drug information item are obtained, including the influence attenuation data, to obtain the first and second wavelength attenuation items; The first and second interval values are obtained by taking the first and second wavelength attenuation items as the interval of the first and second adjustment wavelengths respectively, and the interval threshold is obtained by combining the first and second interval values.

6. The BFS filled side-by-side ampoule quality detection system of claim 1, wherein: The path analysis item includes: Based on the real-time path item, the top point information and the bottom point information of the target row of ampoules are obtained, to obtain the marked top point item and the marked bottom point item, and the marked path is obtained based on the marked top point item and the marked bottom point item. The analysis time is set, and the scanning path analysis is performed based on the combination of the analysis time and the marked path, and the path analysis item is obtained.

7. The BFS filled side-by-side ampoule quality detection system of claim 1, wherein: The first detection threshold is the appearance threshold, including the contour threshold and the sealing threshold, and the first screening item includes: The detection limit value is set based on the contour threshold and the sealing threshold, and the contour offset limit value and the sealing burr limit value are set, to obtain the contour setting item and the sealing setting item; The target row of ampoules that exceeds the contour setting item and the sealing setting item is removed based on the contour setting item and the sealing setting item, and the first screening item is obtained.

8. A method for detecting the quality of BFS filled side-by-side ampoules, characterized in that: The BFS filling row of ampoule quality detection system includes: The scanning module is set based on the position of the row of ampoules, and the bottle information and the drug information of the row of ampoules are obtained; The control wavelength information is obtained based on the bottle information and the drug information, and the first and second adjustment wavelengths are obtained, and the wavelength of the scanning module is adjusted based on the first and second adjustment wavelengths; The moving path of the row of ampoules is obtained, to obtain the real-time path item, and the scanning path analysis is performed based on the real-time path item, to obtain the path analysis item. The target row of ampoules is scanned by the scanning module, to obtain the bottle scanning item and the drug scanning item respectively. The volume reconstruction is performed based on the bottle scanning item and the charge scanning item, and then the bottle reconstruction item and the charge reconstruction item are obtained. The preliminary detection is performed based on the bottle reconstruction item, and the unqualified products are screened out to obtain a first screening item. The secondary detection is performed based on the charge reconstruction item, and the unqualified products are screened out to obtain a second screening item. The double quality detection of the side-by-side ampoule is performed based on the combination of the first screening item and the second screening item.

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