Plant drink and preparation method thereof

Abstract

The invention relates to the technical field of senile dementia prevention, in particular to a plant drink which is used for preventing senile dementia and comprises 10-30 parts by weight of folium ginkgo, 15-25 parts by weight of Chinese yam, 10-20 parts by weight of radix astragali, 8-15 parts by weight of radix salviae miltiorrhizae and 5-10 parts by weight of poria cocos, and each raw material comprises active ingredients. The natural, safe and easy-to-take plant drinking liquid is prepared by selecting the following medicinal materials such as ginkgo leaves, Chinese yam, astragalus membranaceus, salvia miltiorrhiza, poria cocos and the like, proportioning the medicinal materials and extracting active ingredients of the medicinal materials, can effectively improve memory and delay cognitive function decline, and has a prevention effect on senile dementia.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of preventing senile dementia, and particularly relates to a plant drink and a preparation method thereof. BACKGROUND

[0002] Senile dementia (such as Alzheimer's disease) is a neurodegenerative disease that seriously affects the quality of life of the elderly, and its main manifestations are memory loss, cognitive dysfunction, etc. The occurrence of senile dementia is mainly because the abnormal deposition of Aβ (beta-amyloid protein) in the brain triggers a vicious cycle of neuron death, neuroinflammation and Tau pathology. At present, the treatment means for senile dementia is limited, and there are problems such as large side effects and insignificant treatment effect.

[0003] Some active ingredients (such as flavonoids, polysaccharides and saponins) in plants have the effects of antioxidant, anti-inflammatory and improving cognitive function, and can effectively delay the decline of cognitive function. However, there is no report on scientific proportioning and preparing plant drinks from these plant ingredients.

[0004] To this end, the present application provides a plant drink to solve the above-mentioned problems. SUMMARY

[0005] In order to overcome the deficiencies of the prior art, the present application provides a plant drink to solve the problems in the prior art.

[0006] To achieve the above object, the present application provides the following technical scheme:

[0007] A plant drink for preventing senile dementia, comprising: 10-30 parts of ginkgo leaves, 15-25 parts of Chinese yam, 10-20 parts of astragalus, 8-15 parts of salvia miltiorrhiza and 5-10 parts of poria cocos, each component is divided by weight, and each raw material contains active ingredients.

[0008] Preferably, the active ingredients account for more than 10% of the total content.

[0009] Preferably, the active ingredients include flavonoids, polysaccharides and saponin juice.

[0010] Preferably, the content of flavonoids is 4.5%-6.0%, the content of polysaccharides is 5.0%-7.5%, and the content of saponins is 2.0%-3.5%.

[0011] Preferably, the flavonoids are ginkgo flavonoids, and the saponins are astragaloside and tanshinone.

[0012] Preferably, the plant drink is an oral liquid, a concentrated liquid, a granule or an extract.

[0013] The application also provides a preparation method of the plant beverage, comprising the following steps:

[0014] S1, washing and crushing the raw materials to a particle size of 20-60 mesh;

[0015] S2, adding 5-10 times the weight of water to the raw materials, and performing hot water extraction or ultrasonic-assisted extraction, and the extraction time is 20-60 minutes;

[0016] S3, filtering the extraction liquid, and concentrating to 1 / 5-1 / 10 of the original volume to obtain a concentrated liquid;

[0017] S4, adding a natural sweetener according to the taste requirements;

[0018] S5, performing sterile packaging to obtain the finished plant beverage.

[0019] Preferably, the natural sweetener is any one or more of honey and mogroside.

[0020] Preferably, the ultrasonic-assisted extraction has a frequency of 20-40 kHz, a power of 200-500 W, and an extraction temperature control of 50-70°C.

[0021] Compared with the prior art, the application has the beneficial effects that:

[0022] The plant beverage has the effects of improving memory, delaying cognitive function decline, and preventing senile dementia. BRIEF DESCRIPTION OF DRAWINGS

[0023] Figure 1 It is an experimental report of the effect of preventing senile dementia of the application;

[0024] Figure 2 It is the experimental results of Figure 1

[0025] Figure 3 It is the antioxidant and anti-inflammatory effects of Figure 1

[0026] Figure 4 It is the verification of the synergistic effect of the components;

[0027] Figure 5 It is a preparation process flowchart;

[0028] Figure 6 It is an experimental report of the preparation process stability verification; DETAILED DESCRIPTION

[0029] ​​With reference to the accompanying drawings, the technical solutions in the embodiments of the present application will be clearly and completely described below, obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work belong to the scope of protection of the present application.

[0030] The present application provides a plant drink for preventing Alzheimer's disease, which comprises 10-30 parts of ginkgo leaves, 15-25 parts of Chinese yam, 10-20 parts of astragalus, 8-15 parts of salvia miltiorrhiza and 5-10 parts of poria cocos. Each component is divided by weight, and each raw material contains active ingredients.

[0031] Ginkgo leaves have the effects of antioxidant and improving cognitive function; Chinese yam is rich in polysaccharides and has the effects of enhancing memory and anti-aging; astragalus is rich in saponins and has the effects of anti-inflammatory and enhancing immunity; salvia miltiorrhiza is rich in flavonoids and has the effects of antioxidant and improving blood circulation; and poria cocos has the effects of invigorating the spleen and brain and anti-aging. These active ingredients synergize with each other and can prevent Alzheimer's disease from multiple aspects. The antioxidant ingredients can eliminate free radicals in the body, reduce the damage of oxidative stress to nerve cells, and delay the aging and apoptosis of nerve cells. The ingredients that enhance immunity help maintain the overall health of the body and reduce problems such as neuroinflammation caused by the decline of immune system function. The ingredients that improve blood circulation can provide sufficient oxygen and nutrients for the brain, ensuring normal metabolism and function of the brain. The ingredients that invigorate the spleen and brain and enhance memory directly act on the brain to improve the cognitive ability and memory level of the brain. Long-term consumption of this plant drink can reduce the risk of Alzheimer's disease to a certain extent and provide strong protection for the brain health of the elderly. To ensure the effect of the plant drink, high-quality raw materials should be selected. Ginkgo leaves with longer growth period, complete and bright leaf color should be selected, which have higher content of active ingredients. Chinese yam with solid texture and smooth skin should be selected to ensure the polysaccharide content. Astragalus with long and thick strips, solid and soft texture, sweet taste and sufficient powder should be selected, which have more abundant saponin content. Salvia miltiorrhiza with thick and strong root and purple-red skin is the best, which can ensure the content of flavonoids. Poria cocos with black-brown skin and white and delicate inside is the best, which has better invigorating the spleen and brain effect. When drinking, it is recommended to drink 1-2 times a day, 100-200 ml each time, before or half an hour after meals. After a period of continuous drinking, the drinking amount can be adjusted according to the individual physical condition and doctor's advice. At the same time, this plant drink can be consumed long-term as a daily health drink, but it cannot replace drug treatment. If the elderly have symptoms of Alzheimer's disease, they should seek medical treatment in time and follow the doctor's advice for treatment.

[0032] Further, the active ingredients account for more than 10% of the total content.

[0033] Such a high proportion of active ingredients makes the plant drink have significant health benefits. It can more effectively supplement the nutrients needed by the human body, enhance the body's immunity and resistance. It can play a more active role in preventing brain diseases such as Alzheimer's disease, and can achieve better results in invigorating the spleen and benefiting the brain.

[0034] Further, the active ingredients include flavonoids, polysaccharides and saponin juice, preferably the content of flavonoids is 4.5%-6.0%, the content of polysaccharides is 5.0%-7.5%, and the content of saponin is 2.0%-3.5%. In this embodiment, flavonoids are ginkgo flavonoids, saponins are astragaloside and danshensu. The specific experiment is carried out by the following parameters:

[0035] Morris water maze: spatial memory ability (escape latency, number of times crossing the platform);

[0036] New object recognition: short-term memory index (discrimination index ).

[0037] Referring to Figures 1-3 the experiment, it can be concluded that the plant drink of the present application significantly improves the spatial memory (water maze latency is reduced by 42%) and object recognition ability (DI is increased by 110%) of AD model animals, and delays neurodegeneration by increasing SOD activity (increased by 50%), reducing MDA (decreased by 45%) and inflammatory factors (IL-1β decreased by 51%). It can be concluded that the treatment principle of the drink of the present application is to inhibit Aβ deposition and repair oxidative stress damage.

[0038] In this embodiment, the plant drink is an oral liquid, a concentrated liquid, a granule or an extract. The selection of the above dosage forms is mainly based on the stability of the active ingredients and the absorption efficiency of the human body. The oral liquid is convenient to carry and take, and is suitable for daily health care needs; the concentrated liquid is more suitable for special groups who need high-dose supplementation; the granule further improves the release speed of the active ingredients by optimizing the solubility; the extract retains the natural properties of the raw materials while enhancing the convenience of storage. Each dosage form has undergone strict process optimization to ensure the best performance of the active ingredients in different environments.

[0039] This embodiment also verifies the synergistic effect of the components, which proves that the formula combination (non-single herb medicine) has a creative synergistic effect, and the verification effect is as follows Figure 4 The experimental results show that the total drink has the highest Aβ clearance rate, which proves that it has the best efficacy.

[0040] As Figure 5 , based on the above plant drink, the present embodiment provides a preparation method of a plant drink, comprising the following steps:

[0041] S1, washing and crushing the raw materials to a particle size of 20-60 mesh;

[0042] S2, adding 5-10 times the weight of water to the raw materials, and performing hot water extraction or ultrasonic-assisted extraction for 20-60 minutes;

[0043] S3, filtering the extraction liquid and concentrating it to 1 / 5-1 / 10 of the original volume to obtain a concentrated liquid;

[0044] S4, adding a natural sweetener for blending according to the taste requirements;

[0045] S5, performing sterile packaging to produce the finished plant drink.

[0046] S1, washing and crushing the raw materials to a particle size of 20-60 mesh, which removes surface impurities and crushes the raw materials to an appropriate particle size, increasing the contact area between the raw materials and the solvent. This ensures the cleanliness of the raw materials, facilitating more complete extraction in the subsequent process and improving extraction efficiency. S2, adding 5-10 times the weight of water to the raw materials, and performing hot water extraction or ultrasonic-assisted extraction for 20-60 minutes, which dissolves the active ingredients in the raw materials into water. This accelerates the dissolution of active ingredients. The advantage is that it can more efficiently extract active ingredients from the raw materials and shorten the extraction time. S3, filtering the extraction liquid and concentrating it to 1 / 5-1 / 10 of the original volume to obtain a concentrated liquid, which separates solid impurities in the extraction liquid and increases the concentration of active ingredients. The advantage is that it makes the active ingredients more concentrated, preparing for subsequent blending and product production, and reducing the workload of subsequent processing. S4, adding a natural sweetener for blending according to the taste requirements, which improves the taste of the plant drink and makes it more acceptable to consumers. The advantage is that it ensures the naturalness of the product while improving its palatability. S5, performing sterile packaging to produce the finished plant drink, which prevents microbial contamination and extends the shelf life of the product. The advantage is that it ensures the quality stability of the product during storage and sales, allowing consumers to safely consume it. This example produces three batches of plant drinks using the preparation method, as shown in Figure N. All three batches of plant drinks meet the standards.

[0047] Further, the frequency of the ultrasonic-assisted extraction is 20-40 kHz, the power is 200-500 W, and the extraction temperature is controlled at 50-70°C. The time of the ultrasonic-assisted extraction is set at 30-60 minutes to ensure sufficient release of active ingredients. By adjusting the frequency, power and temperature parameters, the characteristics of different kinds of raw materials can be adapted to improve the extraction efficiency. In addition, this method can effectively avoid the destruction of active ingredients caused by excessive temperature or time, thereby better preserving the nutritional value of the plant drink. This optimized process provides a high-quality raw material basis for subsequent steps, further improving the overall quality of the finished product.

[0048] The foregoing description of specific exemplary embodiments of the application is presented for the purpose of illustration and description and is not intended to be limiting of the application as disclosed, and various changes in or substitutions of the embodiments described can occur to those skilled in the art, although changes in the precise development of the embodiments disclosed, there is no intention in the scope of the application, the specific embodiments are merely an explanation of the application, and are not a limitation of the application, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner, the purpose of selecting and describing exemplary embodiments is to explain the specific principles of the application and its practical application, so that those skilled in the art can make modifications, substitutions, variations and various different choices and changes to the embodiments after reading the specification without departing from the principles and spirit of the application, but as long as it is within the scope of the claims of the application, it is protected by the patent law.

Claims

1. A plant-based beverage for the prevention of Alzheimer's disease, characterized in that, include: Ginkgo biloba leaves 10-30 parts, yam 15-25 parts, astragalus 10-20 parts, salvia miltiorrhiza 8-15 parts, poria cocos 5-10 parts. Each component is divided into portions by weight, and each raw material contains active ingredients.

2. The herbal beverage according to claim 1, characterized in that, The active ingredient accounts for more than 10% of the total content.

3. The plant-based beverage according to claim 2, characterized in that, The active ingredients include flavonoids, polysaccharides, and saponins.

4. The herbal beverage according to claim 3, characterized in that, The content of the flavonoids is 4.5%-6.0%, the content of the polysaccharides is 5.0%-7.5%, and the content of the saponins is 2.0%-3.5%.

5. The herbal beverage according to claim 4, characterized in that, The flavonoids are ginkgo flavonoids, and the saponins are astragaloside A and tanshinone.

6. The herbal beverage according to claim 1, characterized in that, The plant-based beverage is an oral liquid, concentrated liquid, granules, or extract.

7. A method for preparing a plant-based beverage, used to produce the plant-based beverage according to any one of claims 1-6, comprising the following steps: S1. Clean and crush the raw materials to a particle size of 20-60 mesh; S2. Add 5-10 times the weight of the raw material to water and perform hot water extraction or ultrasonic-assisted extraction for 20-60 minutes. S3. Filter the extract and concentrate it to 1 / 5-1 / 10 of the original volume to obtain the concentrate; S4. Add natural sweeteners to adjust the flavor according to your taste preferences; S5. Perform aseptic packaging to produce finished plant-based beverage.

8. The method for preparing plant-based beverage according to claim 7, characterized in that, The natural sweetener is any one or more of honey and mogrosides.

9. The method for preparing plant-based beverage according to claim 7, characterized in that, The ultrasonic-assisted extraction has a frequency of 20–40 kHz, a power of 200–500 W, and an extraction temperature of 50–70°C.

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