Composition, medicine with composition, combined medicine and application

Abstract

The invention discloses a composition, a medicine with the composition and application of the composition. The composition comprises radix aconiti carmichaeli and other qi promoting components, a blood stasis dispersing component; components for warming spleen and stomach, dispelling cold, reviving yang and tonifying spleen Liquorice; a blood generating and activating component; a wind-cold dispersing component; a kidney reinforcing component; the composition disclosed by the invention has a good antiviral effect, and can assist qi and blood generation so as to transform cold-dampness, so that antiviral effect is realized, and meanwhile, the body function is improved.

Description

Technical Field

[0001] This invention generally relates to the field of traditional Chinese medicine, and specifically to a composition and a drug having the same, a combination drug, and uses. Background Technology

[0002] Supported by the theories of Traditional Chinese Medicine (TCM) regarding the coordination of the internal organs, meridians, and Qi and blood, the mutual dependence and interdependence of the exterior and interior, and the principle of treatment based on the Eight Principles of Differentiation, this approach addresses pathological manifestations such as chills, inflammation, shortness of breath, and fever caused by the invasion of cold and dampness. It focuses on treating the root cause by combating cold and dampness, thereby alleviating the pathological symptoms of inflammation. The pathological manifestations of wind-cold colds in TCM are consistent with those of viral colds in modern medicine; therefore, the sweating method used in TCM to treat wind-cold syndromes is a simple antiviral therapy. The novel coronavirus is highly active, replicates rapidly in the body, and is difficult to eradicate. Using traditional TCM formulas to dispel wind and cold, such as Da Qinglong Tang, can be too drastic and easily lead to excessive sweating, thus causing a decline in bodily functions. Formulas like Ma Huang Tang and Gui Zhi Tang are also somewhat insufficient in combating the novel coronavirus. Summary of the Invention

[0003] In view of the above-mentioned defects or deficiencies in the prior art, it is desirable to provide a composition and a drug, combination drug and use having the same, wherein the composition has good antiviral effect, avoids excessive sweating, retains vital energy to help blood production and kill viruses, and improves bodily functions.

[0004] In a first aspect, the present invention provides a composition comprising:

[0005] Aconite or other qi-regulating components, the other qi-regulating components are selected from: Citrus aurantium, Melia toosendan, Magnolia officinalis, Ficus pumila, Citrus medica, Curcuma longa, Ephedra sinica, Liquidambar formosana, Piper kadsura, Ephedra sinica, Cinnamomum cassia, Ligusticum chuanxiong, Amomum villosum, Citrus reticulata peel, Cinnamomum cassia, Citrus reticulata peel, Aucklandia lappa, Citrus aurantium, Curcuma zedoaria, Mustard seed, Lindera strychnifolia, Zanthoxylum bungeanum or Citrus reticulata peel;

[0006] The blood-activating and stasis-removing components are selected from one or two of the following: Vaccaria segetalis, Aster tataricus, Paeonia lactiflora, Gleditsia sinensis, Clematis chinensis, Paeonia suffruticosa, Panax notoginseng, Liquidambar formosana resin, Sophora japonica bark, Dragon's blood, Platycodon grandiflorus, Cercis chinensis bark, Hirudo medicinalis, Salvia miltiorrhiza, Tussilago farfara, Prunus persica kernel, Paeonia lactiflora, Prunus armeniaca, Hedyotis diffusa, Sparganium stoloniferum, Carthamus tinctorius, Boswellia carterii, Commiphora myrrha, Rubia cordifolia, Spatholobus suberectus, Corydalis yanhusuo, Achyranthes bidentata, Rhodiola rosea,

[0007] The component for warming the middle energizer and dispelling cold, restoring yang and unblocking the meridians, wherein the warming the middle energizer and dispelling cold, restoring yang and strengthening the spleen are selected from dried ginger, sand ginger, galangal or turmeric;

[0008] Licorice;

[0009] The blood-activating and blood-generating components are selected from one or two of Angelica sinensis, Angelica pubescens, Drynaria fortunei, Acanthopanax senticosus, and Dipsacus asper.

[0010] The components for dispersing wind-cold are selected from cinnamon twig, asarum, ephedra, sesame, perilla, perilla stem, schizonepeta, schizonepeta spike, notopterygium root, angelica root, dried ginger, centipeda grass, garlic, allium macrostemon, magnolia flower or saposhnikovia root;

[0011] The kidney-tonifying component is selected from Rosa laevigata, Cuscuta chinensis, Allium tuberosum, Aster tataricus, Rubus idaeus, Cornus officinalis, Rosa rugosa, Morinda officinalis, Cynomorium songaricum, Epimedium brevicornu, Trigonella foenum-graecum, Alpinia oxyphylla, Mantis religiosa ootheca, Cuttlebone, Schisandra chinensis, Curculigo orchioides, Psoralea corylifolia, or Morus alba.

[0012] According to embodiments of the present invention, the composition further comprises the following additional technical features:

[0013] According to an embodiment of the present invention, the composition comprises:

[0014] 7-13 parts by weight of Aconitum carmichaelii or other qi-regulating components;

[0015] 7-18 parts by weight of the blood-activating and stasis-removing components;

[0016] 7-12 parts by weight of the warming and dispelling cold, restoring yang and unblocking the meridians component;

[0017] 7-12 parts by weight of licorice;

[0018] 7-12 parts by weight of blood-activating and blood-generating components;

[0019] 5-9 parts by weight of the dispersing wind-cold component;

[0020] 5-9 parts by weight of the kidney-strengthening component.

[0021] According to an embodiment of the present invention, the composition comprises:

[0022] The calming component is selected from oyster, pearl powder, amber, arborvitae leaf, arborvitae seed, jujube seed, mimosa flower, polygala, jujube, longan, lily, poria cocos, fleeceflower stem, or mimosa bark.

[0023] and / or

[0024] The heat-clearing and detoxifying components are selected from Bupleurum chinense, Buddleja officinalis, Hedyotis diffusa, mulberry leaf, Allium macrostemon, dandelion, Portulaca oleracea, Forsythia suspensa, Scutellaria baicalensis, Phellodendron chinense, Coptis chinensis, Prunella vulgaris, Uncaria rhynchophylla, Forsythia suspensa, Houttuynia cordata, Fritillaria cirrhosa, Physalis alkekengi, Lithospermum erythrorhizon, Patrinia scabiosaefolia, Gardenia jasminoides, Cassia tora, Lonicera japonica, Viola yedoensis, Tropaeolum majus, Vitex trifolia, Isatis indigotica, Fagopyrum dibotrys, Lonicera japonica, Scutellaria barbata, Lobelia chinensis, Cremastra appendiculata, Ajuga decumbens, Belamcanda chinensis, Isatis indigotica, Andrographis paniculata, Phellodendron chinense, Eriobotrya japonica, Polygonum aviculare, Lonicera japonica, Chrysanthemum morifolium, Chicorydalis yanhusuo, Imperata cylindrica, Phragmites communis, Cirsium japonicum, Cirsium setosum, or Silybum marianum.

[0025] According to an embodiment of the present invention, the composition comprises:

[0026] 7-13 parts by weight of Aconitum carmichaelii or other qi-regulating components;

[0027] 7-18 parts by weight of the blood-activating and stasis-removing components;

[0028] 7-12 parts by weight of the warming and dispelling cold, restoring yang and unblocking the meridians component;

[0029] 7-12 parts by weight of licorice;

[0030] 7-12 parts by weight of blood-activating and blood-generating components;

[0031] 5-9 parts by weight of the dispersing wind-cold component;

[0032] 5-9 parts by weight of the kidney-strengthening component;

[0033] 5-9 parts by weight of the calming component; and / or 7-12 parts by weight of the heat-clearing and detoxifying component.

[0034] According to an embodiment of the present invention, the composition comprises: 7-13 parts by weight of Aconitum carmichaelii, 7-18 parts by weight of Salvia miltiorrhiza, 7-12 parts by weight of Zingiber officinale, 7-12 parts by weight of Glycyrrhiza uralensis, 7-12 parts by weight of Angelica sinensis, 7-12 parts by weight of Bupleurum chinense, 5-9 parts by weight of Ephedra sinica, 5-9 parts by weight of Platycladus orientalis seed, and 5-9 parts by weight of Cornus officinalis.

[0035] Or, the basic side:

[0036] Aconite 7g-12g (or Citrus aurantium 7g-13g), Moutan bark 7g-15g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Ephedra 5g-9g, Cornus officinalis 5g-9g;

[0037] Alternatively, a decoction formula:

[0038] Aconite 7g-12g, Bitter Orange Peel 7g-13g, Moutan Bark 9g-15g, Panax Notoginseng 3g-13g, Dried Ginger 7g-12g, Licorice 7g-12g, Angelica 7g-12g, Bupleurum 7g-12g, Ephedra 5g-9g, Arborvitae Seed 5g-9g, Cornus officinalis 5g-9g;

[0039] Alternatively, a powder formulation:

[0040] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0041] Aconite 7g-12g, Moutan bark 9g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Bupleurum chinense 7g-12g, Ephedra sinica 5g-9g, Platycladus orientalis seed 5g-9g, Cornus officinalis 5g-9g;

[0042] Alternatively, option B is suitable for patients without underlying medical conditions.

[0043] Citrus aurantium 7g-13g, Paeonia suffruticosa 9g-16g, Zingiber officinale 7g-12g, Glycyrrhiza uralensis 7g-12g, Angelica sinensis 7g-12g, Bupleurum chinense 7g-12g, Ephedra sinica 5g-9g, Platycladus orientalis seed 5g-9g, Cornus officinalis 5g-9g;

[0044] Or, the basic side:

[0045] Aconite 7g-12g (or Sichuan pepper 7g-13g), white peony root 9g-15g, dried ginger 7g-12g, licorice root 7g-12g, angelica root 7g-12g, sesame oil 5g-9g, psoralea fruit 5g-9g;

[0046] Alternatively, a decoction formula:

[0047] Aconite 7g-12g, Sichuan pepper 7g-13g, white peony root 9g-15g, Panax notoginseng 3g-13g, dried ginger 7g-12g, licorice root 7g-12g, angelica root 7g-12g, mulberry leaf 7g-12g, sesame oil 5g-9g, polygala root 5g-9g, psoralea fruit 5g-9g;

[0048] Alternatively, a powder formulation:

[0049] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0050] Aconite 7g-12g, White peony root 9g-16g, Dried ginger 7g-12g, Licorice root 7g-12g, Angelica sinensis 7g-12g, Mulberry leaf 7g-12g, Mosla chinensis 5g-9g, Polygala tenuifolia 5g-9g, Psoralea corylifolia 5g-9g;

[0051] Alternatively, option B is suitable for patients without underlying medical conditions.

[0052] 7g-13g of Sichuan pepper, 9g-16g of white peony root, 7g-12g of dried ginger, 7g-12g of licorice root, 7g-12g of angelica root, 7g-12g of mulberry leaf, 5g-9g of sesame, 5g-9g of polygala root, and 5g-9g of psoralea root;

[0053] Or, the basic side:

[0054] Aconite 7g-12g (or Curcuma longa 7g-13g), Liquidambar formosana resin 3g-10g, Alpinia officinarum 7g-12g, Glycyrrhiza uralensis 7g-12g, Angelica sinensis 7g-12g, Perilla frutescens 5g-9g, Alpinia oxyphylla 5g-9g;

[0055] Alternatively, a decoction formula:

[0056] Aconite 7g-12g, Curcuma longa 7-13g, Liquidambar formosana resin 3g-10g, Paeonia lactiflora 9g-15g, Alpinia officinarum 7g-12g, Glycyrrhiza uralensis 7g-12g, Angelica sinensis 7g-12g, Perilla frutescens 5g-9g, Prunella vulgaris 7g-12g, Albizia julibrissin bark 5g-9g, Alpinia oxyphylla 5g-9g;

[0057] Alternatively, a powder formulation:

[0058] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0059] Aconite 7g-12g, Liquidambar resin 3g-10g, Alpinia officinarum 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Prunella vulgaris 7g-12g, Perilla frutescens 5g-9g, Albizia julibrissin bark 5g-9g, Alpinia oxyphylla 5g-9g;

[0060] Alternatively, option B is suitable for patients without underlying medical conditions.

[0061] Curcuma longa 7g-13g, Liquidambar formosana resin 3g-10g, Alpinia officinarum 7g-12g, Glycyrrhiza uralensis 7g-12g, Angelica sinensis 7g-12g, Prunella vulgaris 7g-12g, Perilla frutescens 5g-9g, Albizia julibrissin bark 5g-9g, Alpinia oxyphylla 5g-9g

[0062] Or, the basic side:

[0063] Aconite 7g-12g (or Magnolia officinalis 7g-13g), Dragon's Blood 3g-10g, Dried Ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Schizonepeta tenuifolia 5g-9g, Rosa laevigata 5g-9g;

[0064] Alternatively, a decoction formula:

[0065] Aconite 7g-12g, Magnolia officinalis 5-9g, Dragon's Blood 3g-10g, Vaccaria segetalis 7-9g, Dried Ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Schizonepeta tenuifolia 5g-9g, Lobelia chinensis 7g-12g, Ziziphus jujuba var. spinosa 5g-9g, Rosa laevigata 5g-9g;

[0066] Alternatively, a powder formulation:

[0067] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0068] Aconite 7g-12g, Dragon's Blood 3g-10g, Dried Ginger 7g-12g, Licorice 7g-12g, Angelica 7g-12g, Lobelia 7g-12g, Schizonepeta 5g-9g, Ziziphus jujuba seed 5g-9g, Rosa laevigata fruit 5g-9g;

[0069] Alternatively, option B is suitable for patients without underlying medical conditions.

[0070] Magnolia officinalis 7g-13g, dragon's blood 3g-10g, dried ginger 7g-12g, licorice 7g-12g, angelica sinensis 7g-12g, lobelia chinensis 7g-12g, schizonepeta tenuifolia 5g-9g, jujube seed 5g-9g, rosehip 5g-9g;

[0071] Or, the basic side:

[0072] Aconite 7g-12g (or Ephedra 7g-13g), Sophora japonica bark 7g-16g (or Platycodon grandiflorus 7g-16g), dried ginger 7g-12g, licorice 7g-12g, angelica sinensis 7g-12g, notopterygium incisum 5g-9g, morinda officinalis 5g-9g;

[0073] Alternatively, a decoction formula:

[0074] Aconite 7g-12g, Ephedra 7g-13g, Sophora japonica bark 7g-16g, Platycodon grandiflorus 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Notopterygium incisum 5g-9g, Forsythia suspensa 7g-12g, Albizia julibrissin flower 5g-9g, Morinda officinalis 5g-9g;

[0075] Alternatively, a powder formulation:

[0076] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0077] Aconite root 7g-12g, Sophora japonica bark 9g-16g, dried ginger 7g-12g, licorice root 7g-12g, angelica sinensis 7g-12g, forsythia suspensa 7g-12g, notopterygium incisum 5g-9g, albizia julibrissin flower 5g-9g, morinda officinalis 5g-9g;

[0078] Alternatively, option B is suitable for patients without underlying medical conditions.

[0079] Ephedra 7g-13g, Sophora japonica bark 9g-16g, dried ginger 7g-12g, licorice 7g-12g, angelica sinensis 7g-12g, forsythia suspensa 7g-12g, notopterygium incisum 5g-9g, albizia julibrissin flower 5g-9g, morinda officinalis 5g-9g;

[0080] Or, the basic side:

[0081] Aconite 7g-12g (or Piper kadsura 7g-13g), Clematis armandii 7g-16g (or Vaccaria segetalis 7g-16g), dried ginger 7g-12g, licorice 7g-12g, angelica sinensis 7g-12g, Schizonepeta tenuifolia 5g-9g, and septum 5g-9g.

[0082] Alternatively, a decoction formula:

[0083] Aconite 7g-12g, Piper kadsura 7-13g, Clematis armandii 7g-16g, Vaccaria segetalis 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Schizonepeta tenuifolia 5g-9g, Phellodendron chinense 7g-12g, Polygonum multiflorum vine 5g-9g, and Polygonum septum 5g-9g.

[0084] Alternatively, a powder formulation:

[0085] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0086] Aconite 7g-12g, Clematis chinensis 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Schizonepeta tenuifolia spike 5g-9g, Phellodendron chinense 7g-12g, Polygonum multiflorum vine 5g-9g, and septum 5g-9g;

[0087] Alternatively, option B is suitable for patients without underlying medical conditions.

[0088] Sea breeze vine 7g-13g, clematis root 7g-16g, dried ginger 7g-12g, licorice root 7g-12g, angelica root 7g-12g, schizonepeta spike 5g-9g, phellodendron bark 7g-12g, fleeceflower root vine 5g-9g, septum 5g-9g;

[0089] Or, the basic side:

[0090] Aconite 7g-12g (or Ficus pumila 7g-13g), Bauhinia bark 7g-16g, dried ginger 7g-12g, licorice 7g-12g, Dipsacus asper 7g-12g, Notopterygium root 5g-9g, Psoralea corylifolia 5g-9g;

[0091] Alternatively, a decoction formula:

[0092] Aconite 7g-12g, Cubeb 7-13g, Bauhinia bark 7g-16g, Vaccaria segetalis 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Dipsacus asper 7g-12g, Notopterygium root 5g-9g, Houttuynia cordata 7g-12g, Platycladus orientalis leaf 5g-9g, Psoralea corylifolia 5g-9g;

[0093] Alternatively, a powder formulation:

[0094] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0095] Aconite root 7g-12g, Bauhinia bark 7g-16g, dried ginger 7g-12g, licorice root 7g-12g, Sichuan teasel root 7g-12g, Notopterygium root 5g-9g, Houttuynia cordata 7g-12g, Platycladus orientalis leaf 5g-9g, Psoralea corylifolia 5g-9g;

[0096] Alternatively, option B is suitable for patients without underlying medical conditions.

[0097] 7g-13g of cubeb, 7g-16g of Bauhinia bark, 7g-12g of dried ginger, 7g-12g of licorice root, 7g-12g of Dipsacus root, 5g-9g of Notopterygium root, 7g-12g of Houttuynia cordata, 5g-9g of Platycladus orientalis leaf, and 5g-9g of Psoralea corylifolia.

[0098] Or, the basic side:

[0099] Aconite 7g-12g (or costus root 7g-13g), Gleditsia sinensis 5g-13g, dried ginger 7g-12g, licorice 7g-12g, angelica sinensis 7g-12g, asarum 5g-9g, fenugreek 5g-9g;

[0100] Alternatively, a decoction formula:

[0101] Aconite 7g-12g, Sichuan costus root 7-13g, Gleditsia sinensis 7g-16g, Platycodon grandiflorus 7-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Asarum 5g-9g, Fagopyrum dibotrys 7g-12g, Fenugreek 5g-9g, Poria cocos 5g-9g;

[0102] Alternatively, a powder formulation:

[0103] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0104] Aconite 7g-12g, Gleditsia sinensis 7g-16g, Platycodon grandiflorus 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Asarum 5g-9g, Fagopyrum dibotrys 7g-12g, Fenugreek 5g-9g, Poria cocos 5g-9g;

[0105] Alternatively, option B is suitable for patients without underlying medical conditions.

[0106] 7g-13g of Sichuan costus root, 7g-16g of soapberry, 7g-16g of platycodon root, 7g-12g of dried ginger, 7g-12g of licorice root, 7g-12g of angelica root, 5g-9g of asarum, 7g-12g of buckwheat, 5g-9g of fenugreek, and 5g-9g of poria cocos.

[0107] Or, the basic side:

[0108] Aconite 7g-12g (or Liquidambar formosana 7-13g), leech 1g-13g, Panax notoginseng 3g-13g, dried ginger 7g-12g, licorice 7g-12g, angelica 7g-12g, centipeda minima 5-9g, Alpinia oxyphylla 5g-9g;

[0109] Alternatively, a decoction formula:

[0110] Aconite 7g-12g, Liquidambar formosana 7g-13g, Leech 1g-13g, Panax notoginseng 3g-13g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Centipeda minima 7g-12g, Gardenia 7g-12g, Alpinia oxyphylla 5g-9g, Platycladus orientalis 5g-9g;

[0111] Alternatively, a powder formulation:

[0112] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0113] Aconite 7g-12g, Leech 1g-13g, Panax notoginseng 3g-13g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Centipeda minima 7g-12g, Gardenia 7g-12g, Alpinia oxyphylla 5g-9g, Platycladus orientalis 5g-9g;

[0114] Alternatively, option B is suitable for patients without underlying medical conditions.

[0115] 7g-13g of *Luffa cylindrica*, 1g-13g of leech, 3g-13g of *Panax notoginseng*, 7g-12g of dried ginger, 7g-12g of licorice root, 7g-12g of angelica sinensis, 7g-12g of *Centipeda minima*, 7g-12g of gardenia, 5g-9g of *Alpinia oxyphylla*, and 5g-9g of *Platycladus orientalis*.

[0116] Or, the basic side:

[0117] Aconite 7g-12g (or Ligusticum chuanxiong 7g-13g), Salvia miltiorrhiza 7g-16g, dried ginger 7g-12g, licorice 7g-12g, Angelica sinensis 7g-12g, Elsholtzia ciliata 5g-9g, Cuscuta chinensis 5g-9g;

[0118] Alternatively, a decoction formula:

[0119] Aconite 7g-12g, Ligusticum chuanxiong 7g-13g, Salvia miltiorrhiza 7g-16g, Peucedanum praeruptorum 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Elsholtzia ciliata 5g-9g, Cuscuta chinensis 5g-9g, Bupleurum chinense 7g-12g, Ziziphus jujuba 5g-9g;

[0120] Alternatively, a powder formulation:

[0121] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0122] Aconite 7g-12g, Salvia miltiorrhiza 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Elsholtzia ciliata 5g-9g, Cuscuta chinensis 5g-9g, Bupleurum chinense 7g-12g, Jujube 5g-9g;

[0123] Alternatively, option B is suitable for patients without underlying medical conditions.

[0124] Chuanxiong 7g-13g, Danshen 7g-16g, dried ginger 7g-12g, licorice 7g-12g, angelica 7g-12g, sesame 5g-9g, dodder seed 5g-9g, bupleurum 7g-12g, jujube 5g-9g;

[0125] Or, the basic method,

[0126] Aconite 7g-12g (or green tangerine peel 7g-13g), Corydalis 7g-16g, dried ginger 7g-12g, licorice 7g-12g, angelica 7g-12g, saposhnikovia 5g-9g, cornus 5g-9g;

[0127] Alternatively, a decoction formula:

[0128] Aconite 7g-12g, Citrus reticulata peel 7g-13g, Corydalis yanhusuo 7g-16g, Aster tataricus 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Saposhnikovia divaricata 5g-9g, Cornus officinalis 5g-9g, Vitex trifolia 7g-12g, Pearl powder 5g-9g;

[0129] Alternatively, a powder formulation:

[0130] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0131] Aconite 7g-12g, Corydalis 7g-16g, Dried Ginger 7g-12g, Licorice 7g-12g, Angelica 7g-12g, Saposhnikovia 5g-9g, Cornus officinalis 5g-9g, Vitex trifolia 7g-12g, Pearl Powder 5g-9g;

[0132] Alternatively, option B is suitable for patients without underlying medical conditions.

[0133] Green tangerine peel 7g-13g, Corydalis rhizome 7g-16g, dried ginger 7g-12g, licorice root 7g-12g, angelica root 7g-12g, saposhnikovia root 5g-9g, cornus fruit 5g-9g, vitex fruit 7g-12g, pearl powder 5g-9g;

[0134] Or, the basic side:

[0135] Aconite 7g-12g (or Costus root 7g-13g), Achyranthes bidentata 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica pubescens 7g-12g, Cinnamon twig 5g-9g, Astragalus membranaceus 5g-9g;

[0136] Alternatively, a decoction formula:

[0137] Aconite 7g-12g, Costus root 7g-13g, Achyranthes root 7g-16g, Vaccaria seed 7g-16g, Dried ginger 7g-12g, Licorice root 7g-12g, Angelica pubescens root 7g-12g, Cinnamon twig 5g-9g, Astragalus seed 5g-9g, Ajuga herb 7g-12g, Poria cocos 5g-9g;

[0138] Alternatively, a powder formulation:

[0139] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0140] Aconite root 7g-12g, Achyranthes root 7g-16g, Dried ginger 7g-12g, Licorice root 7g-12g, Angelica pubescens root 7g-12g, Cinnamon twig 5g-9g, Astragalus seed 5g-9g, Ajuga decumbens 7g-12g, Poria cocos 5g-9g

[0141] Alternatively, option B is suitable for patients without underlying medical conditions.

[0142] Costus root 7g-13g, Achyranthes root 7g-16g, Dried ginger 7g-12g, Licorice root 7g-12g, Angelica pubescens root 7g-12g, Cinnamon twig 5g-9g, Astragalus seed 5g-9g, Ajuga herb 7g-12g, Poria cocos 5g-9g

[0143] Or, basic side

[0144] Aconite 7g-12g (or Citrus reticulata peel 7g-13g), Spatholobus suberectus 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Schizonepeta tenuifolia spike 5g-9g, Cornus officinalis 5g-9g;

[0145] Alternatively, a decoction formula:

[0146] Aconite 7g-12g, Citrus reticulata peel 7g-13g, Spatholobus suberectus 7g-16g, Carthamus tinctorius 7g-16g, Dried ginger 7g-12g, Licorice root 7g-12g, Angelica sinensis 7g-12g, Schizonepeta tenuifolia spike 5g-9g, Cornus officinalis 5g-9g, Lonicera japonica vine 7g-12g, Oyster shell 7g-12g;

[0147] Alternatively, a powder formulation:

[0148] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0149] Aconite 7g-12g, Spatholobus suberectus 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Schizonepeta tenuifolia 5g-9g, Cornus officinalis 5g-9g, Lonicera japonica 7g-12g, Oyster shell 7g-12g;

[0150] Alternatively, option B is suitable for patients without underlying medical conditions.

[0151] Tangerine peel 7g-13g, chicken blood vine 7g-16g, dried ginger 7g-12g, licorice 7g-12g, angelica 7g-12g, schizonepeta spike 5g-9g, cornus officinalis 5g-9g, honeysuckle vine 7g-12g, oyster shell 7g-12g.

[0152] In a second aspect, the present invention provides a medicament comprising the composition of the first aspect.

[0153] According to an embodiment of the present invention, the drug further includes excipients;

[0154] According to embodiments of the present invention, the dosage form of the drug is selected from decoction, powder, injection, tablet, tincture or pill.

[0155] Thirdly, the present invention provides a combined medicament, comprising: the medicament of the second aspect;

[0156] Substances containing protein are selected from protein powder, eggs, lean meat, and other high-protein foods.

[0157] Fourthly, the present invention provides the use of the composition of the first aspect in the preparation of a medicament for antiviral purposes;

[0158] Optionally, the virus may be selected from coronaviruses;

[0159] Optionally, the virus was selected from the novel coronavirus SARS-CoV-2.

[0160] According to an embodiment of the present invention, the drug is used for antidepressant purposes.

[0161] According to an embodiment of the present invention, the method for improving cardiopulmonary function;

[0162] In some embodiments, the drug is used to prevent or treat cardiovascular and cerebrovascular diseases, myocarditis, COPD, and coronary heart disease.

[0163] According to an embodiment of the present invention, the drug is used to prevent or treat muscle soreness and improve joint mobility.

[0164] According to embodiments of the present invention, the drug is used to enhance metabolism and hormone secretion in the body.

[0165] According to an embodiment of the present invention, the drug is used to regulate blood circulation;

[0166] In some embodiments, the drug is used to prevent or treat migraines.

[0167] The composition of this invention combines modern pathology and basic theories of traditional Chinese medicine. It warms the interior and dispels blood stasis, thus strengthening the functions of the internal organs, regulating blood circulation, enhancing bodily functions, and promoting the generation of blood and qi to dispel cold and dampness. Referring to the sweating and dampness-dispelling methods in traditional prescriptions, it retains vital energy to promote blood generation and eliminate viruses. Simultaneously, it effectively prevents thrombosis and cardiovascular disease in patients with underlying diseases during immune resistance, avoiding the tragedy of sudden death and reducing mortality. When taken with protein, the composition of this invention can increase the conversion rate of immunoglobulins in the body, further effectively inhibiting viral replication and blocking viral proliferation. Detailed Implementation

[0168] The present application will now be described in further detail with reference to the embodiments. It is to be understood that the specific embodiments described herein are for illustrative purposes only and are not intended to limit the invention.

[0169] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. The present application will now be described in detail with reference to the embodiments.

[0170] Composition

[0171] In a first aspect, embodiments of the present invention provide a composition comprising:

[0172] Aconite or other qi-regulating components, the other qi-regulating components are selected from: Citrus aurantium, Melia toosendan, Magnolia officinalis, Ficus pumila, Citrus medica, Curcuma longa, Ephedra sinica, Liquidambar formosana, Piper kadsura, Ephedra sinica, Cinnamomum cassia, Ligusticum chuanxiong, Amomum villosum, Citrus reticulata peel, Cinnamomum cassia, Citrus reticulata peel, Aucklandia lappa, Citrus aurantium, Curcuma zedoaria, Mustard seed, Lindera strychnifolia, Zanthoxylum bungeanum or Citrus reticulata peel;

[0173] The blood-activating and stasis-removing components are selected from one or two of the following: Vaccaria segetalis, Aster tataricus, Paeonia lactiflora, Gleditsia sinensis, Clematis chinensis, Paeonia suffruticosa, Panax notoginseng, Liquidambar formosana resin, Sophora japonica bark, Dragon's blood, Platycodon grandiflorus, Cercis chinensis bark, Hirudo medicinalis, Salvia miltiorrhiza, Tussilago farfara, Prunus persica kernel, Paeonia lactiflora, Prunus armeniaca, Hedyotis diffusa, Sparganium stoloniferum, Carthamus tinctorius, Boswellia carterii, Commiphora myrrha, Rubia cordifolia, Spatholobus suberectus, Corydalis yanhusuo, Achyranthes bidentata, Rhodiola rosea,

[0174] The component for warming the middle energizer and dispelling cold, restoring yang and unblocking the meridians, wherein the warming the middle energizer and dispelling cold, restoring yang and strengthening the spleen are selected from dried ginger, sand ginger, galangal or turmeric;

[0175] Licorice;

[0176] The blood-activating and blood-generating components are selected from one or two of Angelica sinensis, Angelica pubescens, Drynaria fortunei, Acanthopanax senticosus, and Dipsacus asper.

[0177] The components for dispersing wind-cold are selected from cinnamon twig, asarum, ephedra, sesame, perilla, perilla stem, schizonepeta, schizonepeta spike, notopterygium root, angelica root, dried ginger, centipeda grass, garlic, allium macrostemon, magnolia flower or saposhnikovia root;

[0178] The kidney-tonifying component is selected from Rosa laevigata, Cuscuta chinensis, Allium tuberosum, Aster tataricus, Rubus idaeus, Cornus officinalis, Rosa rugosa, Morinda officinalis, Cynomorium songaricum, Epimedium brevicornu, Trigonella foenum-graecum, Alpinia oxyphylla, Mantis religiosa ootheca, Cuttlebone, Schisandra chinensis, Curculigo orchioides, Psoralea corylifolia, or Morus alba.

[0179] The purpose of this formula is to resist the replication of the novel coronavirus in the body and eliminate the inflammatory response. The initial pathological manifestations caused by the novel coronavirus, such as chills, fatigue, weakness, body aches and pains, and fever, are consistent with the pathological phenomena of the common cold caused by wind-cold in traditional Chinese medicine. Therefore, the treatment of cold and dampness in traditional Chinese medicine is continued. However, the pathological manifestations caused by the novel coronavirus infection are more persistent and lingering, indicating that the novel coronavirus is more active than the common cold and influenza viruses. Combining the principles of modern pathology, anatomy, and microbiology, the original traditional Chinese medicine methods of sweating and removing dampness are improved to form a warming and dampness-resolving method. Combined with protein intake, this warming and dampness-resolving method enhances the function of the internal organs, improves the body's function, and promotes the rapid and efficient production of immune albumin to inhibit viral replication in the body, thereby achieving the purpose of antiviral treatment and eliminating the inflammatory response.

[0180] In this basic formula, the principal herbs for resolving blood stasis, such as Salvia miltiorrhiza, Paeonia lactiflora, Corydalis yanhusuo, Hedyotis diffusa, Boswellia carterii, Commiphora myrrha, Prunus persica, Carthamus tinctorius, Daemonorops draco, Rhodiola rosea, and Spatholobus suberectus, are used to resolve cold-induced blood stasis and promote the smooth flow of blood. The secondary herbs for promoting qi circulation and activating blood circulation, especially Aconitum carmichaelii, are used to restore yang, warm the meridians, dispel cold, tonify fire, and assist yang. They are effective in dispelling cold, promoting blood circulation, and clearing blood stasis, especially beneficial for individuals with underlying diseases whose bodily functions have declined and whose energy production is insufficient. Therefore, the intense heat of Aconitum carmichaelii is used to counteract the extreme coldness caused by COVID-19 infection. For individuals without underlying diseases, milder qi-regulating and qi-dispersing components are used instead, such as Cinnamomum cassia, Ligusticum chuanxiong, Lindera strychnifolia, Citrus reticulata peel, Citrus aurantium, Curcuma longa, Cyperus rotundus, Citrus reticulata peel, Curcuma zedoaria, and Citrus aurantium. Angelica sinensis invigorates blood and replenishes the blood and qi deficiency caused by cold stagnation; when blood is sufficient, the pathogenic factor recedes. Dried ginger warms the middle jiao, dispels cold, restores yang, unblocks the meridians, warms the lungs, and transforms phlegm. Together with Glycyrrhiza uralensis and kidney-tonifying herbs, it serves as an adjuvant. The kidney-tonifying herbs strengthen kidney qi and assist in the generation of qi and blood. Wind-cold dispersing herbs are used as guiding herbs to preserve the channels for the dissipation of dampness. In extended formulas, calming and yin-nourishing herbs are added to reduce side effects, and heat-clearing and detoxifying herbs are added to clear possible symptoms of wind-cold combined with wind-heat cold.

[0181] The above seven types of medicines were developed by the inventors through extensive theoretical analysis and experimental optimization. Based on the fundamental theories of Traditional Chinese Medicine (TCM) and the four natures and five flavors of Chinese herbs, and adhering to the principle of principal, assistant, adjuvant, and guide herbs, the principal herb is used to invigorate blood and remove blood stasis. The assistant herb, combined with Angelica sinensis, promotes qi circulation and generates blood to resolve dampness. The adjuvant herbs, such as kidney-tonifying herbs, strengthen kidney qi to generate blood, calm the mind to nourish yin, and dispel wind-cold, serve as guide herbs. Dried ginger and licorice work together to enhance the therapeutic effect, maximizing the efficacy of the medicinal slices and achieving the desired results. These herbs effectively warm the interior, remove blood stasis, strengthen organ function, regulate qi and blood circulation, enhance bodily functions, and promote the generation of qi and blood to dispel cold-dampness and fight viruses. Aconite, being pungent, sweet, and very hot, has the effects of restoring yang, tonifying fire, and dispelling cold and relieving pain. Aconite works synergistically with blood-stasis-removing, wind-cold-dispelling, and kidney-tonifying herbs to effectively promote the generation of qi and blood, relieve pain, improve bodily functions, and achieve antiviral effects. For patients infected with COVID-19, it can effectively inhibit viral replication, reduce symptoms, and relieve pain.

[0182] Each type of herb in the above-mentioned composition can be arranged and combined arbitrarily; and according to the individual differences of patients, such as gender, age, strength, symptoms, and condition, formulas suitable for different ages and health conditions can be formulated. For example 1: Aconitum carmichaelii, Paeonia suffruticosa, Zingiber officinale, Glycyrrhiza uralensis, Angelica sinensis, Ephedra sinica, Rosa laevigata; For example 2: Aconitum carmichaelii, Paeonia lactiflora, Zingiber officinale, Glycyrrhiza uralensis, Angelica sinensis, Elsholtzia ciliata, Allium tuberosum seed; For example 3: Aconitum carmichaelii, Gleditsia sinensis, Zingiber officinale, Glycyrrhiza uralensis, Angelica sinensis, Magnolia biondii, Rosa laevigata.

[0183] According to embodiments of the present invention, the composition comprises: 7-13 parts by weight of Aconitum carmichaelii or other qi-regulating components; 7-18 parts by weight of blood-activating components; 7-12 parts by weight of warming the middle jiao and dispelling cold, restoring yang and unblocking the meridians components; 7-12 parts by weight of Glycyrrhiza uralensis; 7-12 parts by weight of blood-activating and blood-generating components; 5-9 parts by weight of wind-cold dispersing components; and 5-9 parts by weight of kidney-tonifying components. The inventors obtained the above-mentioned optimal ratio through extensive experiments, thereby further enhancing the warming and blood-activating properties, strengthening the functions of the internal organs, regulating qi and blood circulation, enhancing bodily functions, and assisting in the generation of qi and blood to dispel cold and dampness, thereby achieving the purpose of antiviral therapy.

[0184] Further, according to embodiments of the present invention, the composition further includes: a sedative component selected from one of the following: oyster shell, pearl powder, amber, arborvitae leaf, arborvitae seed, jujube seed, albizia flower, polygala root, jujube, longan, lily bulb, poria cocos, fleeceflower root vine, or albizia bark; and a heat-clearing and detoxifying component selected from one of the following: bupleurum root, buddleja flower, oldenlandia diffusa, mulberry leaf, allium macrostemon, dandelion, purslane, forsythia, scutellaria baicalensis, phellodendron bark, and scutellaria barbata. One of the following: Forsythia suspensa, Prunella vulgaris, Cat's Claw Grass, Forsythia suspensa, Houttuynia cordata, Fritillaria cirrhosa, Physalis alkekengi, Lithospermum erythrorhizon, Patrinia scabiosaefolia, Gardenia jasminoides, Cassia tora, Lonicera japonica, Viola yedoensis, Nasturtium sinense, Vitex trifolia, Isatis tinctoria, Fagopyrum cylindrica, Lonicera japonica, Scutellaria barbata, Lobelia chinensis, Cremastra appendiculata, Ajuga decumbens, Belamcanda chinensis, Isatis indigotica, Andrographis paniculata, Phellodendron chinense, Eriobotrya japonica, Polygonum aviculare, Lonicera japonica, Chrysanthemum morifolium, Chicory, Imperata cylindrica, Phragmites communis, Cirsium japonicum, Cirsium setosum, or Silybum marianum.

[0185] In this embodiment, a calming component is added to the basic formula described above, which effectively improves the efficacy of the formula and reduces side effects. The addition of a heat-clearing and detoxifying component addresses the possibility of concurrent bacterial infection with viral infection, while also providing liver protection. Especially for patients with underlying diseases (excluding those in the acute phase of hypertension and organ transplant recipients), the formula in this embodiment warms the interior, removes blood stasis, and promotes the generation of qi and blood, achieving antiviral effects with minimal side effects and avoiding complications, thus ensuring medication safety for patients with underlying diseases.

[0186] Further, according to embodiments of the present invention, the composition comprises: 7-13 parts by weight of Aconitum carmichaelii; 7-18 parts by weight of a blood-activating component; 7-12 parts by weight of a spleen-strengthening, cold-dispersing, yang-restoring, and spleen-tonifying component; 7-12 parts by weight of Glycyrrhiza uralensis; 7-12 parts by weight of a blood-generating component; 5-9 parts by weight of a wind-cold-dispersing component; 5-9 parts by weight of a kidney-tonifying component; 5-9 parts by weight of a sedative component; and / or 7-12 parts by weight of a heat-clearing and detoxifying component. The dosage according to this embodiment ensures good efficacy, achieving antiviral effects while reducing drug side effects, restoring bodily functions, regulating hormones, and improving patient mood.

[0187] It should be noted that the composition of the present invention can be made into a decoction or a powder. The powder has a more direct therapeutic effect and is more effective than the decoction. Therefore, the proportions can be adjusted appropriately when using it.

[0188] drug

[0189] Secondly, embodiments of the present invention provide a medicament comprising the composition of the first aspect. Thus, the medicament according to embodiments of the present invention has antiviral effects, can promote blood and qi production, enhance bodily functions, and achieve the purpose of antiviral action.

[0190] According to an embodiment of the present invention, the drug further includes excipients. This helps to better exert the drug's efficacy and improve its flavor, texture, stability, etc.

[0191] When taking this medication, it can also be taken with protein powder, eggs, or other high-protein foods to help the body produce immune proteins.

[0192] Furthermore, the present invention provides a combined drug, including the drug of the second aspect; a protein-containing substance, wherein the protein-containing substance is selected from high-protein substances such as protein powder, eggs, and lean meat.

[0193] According to embodiments of the present invention, the dosage form of the drug is selected from one of the following: decoction, powder, tablet, injection, tincture, or pill. This allows for the use of different dosage forms depending on the target patient or ease of use. For example, powder or pill can be used for ease of administration; decoction can be used for better taste; and the dosage form can be adjusted according to the absorption site and release requirements of the drug, thereby improving bioavailability and prolonging the release time. For patients with severe conditions, injection can be used to achieve high-dose administration and avoid the influence of gastrointestinal circulation on the active ingredients of the drug.

[0194] Those skilled in the art will understand that the features and advantages described above with respect to the composition also apply to this drug and will not be repeated here.

[0195] Method of drug use according to embodiments of the present invention:

[0196] In practical use, the method for preparing the medicine according to the embodiments of the present invention includes: soaking all the medicinal materials in the formula in water, heating to boiling and continuing to decoct (for 30 to 60 minutes), filtering, and collecting the first extract; then adding water to the filtered residue and heating to boiling, continuing to decoct (for 30 to 60 minutes, to ensure that the effective components in the medicinal materials are completely dissolved, which helps to better exert the medicinal effect), filtering, and collecting the second extract; mixing the first extract and the second extract to obtain the decoction of the medicine.

[0197] The method for preparing the drug according to an embodiment of the present invention further includes: pulverizing all the medicinal materials in the formula into powder, mixing them evenly, and obtaining the drug powder.

[0198] In actual use, the powder of the present invention is prepared as a powder and administered at a dosage of 15-25g per dose, 1-4 times daily, according to individual differences in symptoms and condition. This is because the powder has a more direct and stronger effect than decoctions, allowing for a reduction in dosage. The dosage can be adjusted based on individual patient differences, such as gender, age, strength, symptoms, and condition, to create suitable dosages for different ages and health conditions.

[0199] When taken as a decoction, the dosage should be increased to ensure that the effective components of the decoction are extracted and effective. The dosage of the decoction should be 200-300 ml each time, 2-4 times a day, depending on the individual, symptoms and condition.

[0200] During antiviral treatment, combining it with 20-30g of protein powder or 1-2 eggs can enhance the effect, especially for COVID-19 patients, where the combination of protein powder or eggs has a significant therapeutic effect.

[0201] use

[0202] Thirdly, embodiments of the present invention propose the use of the composition of the first aspect in the preparation of a medicament. According to embodiments of the present invention, the medicament has antiviral activity, such as against coronaviruses (SARS-CoV-2), influenza viruses, and varicella-zoster viruses. In particular, when used for antiviral treatment, its effect is better when combined with proteins, exhibiting broad-spectrum antiviral efficacy.

[0203] In clinical trials, for patients infected with COVID-19, after taking this drug, symptoms were alleviated, body temperature did not spike, symptoms disappeared in 5-8 days, and the test came back negative in 6 days; for influenza, taking this drug did not cause a rise in body temperature, and patients generally recovered in about 3 days with all symptoms disappearing; for the common cold, taking this drug immediately relieved runny nose, did not cause a rise in body temperature, and patients recovered in 1-3 days with all symptoms disappearing.

[0204] According to embodiments of the present invention, the drug has an antidepressant effect. The drug of the embodiments of the present invention can increase the secretion of bodily hormones, while regulating blood circulation and increasing excitability, thus effectively improving the patient's mood and exhibiting an antidepressant effect.

[0205] According to embodiments of the present invention, the drug is used to improve cardiopulmonary function. The drug of embodiments of the present invention has significant therapeutic effects on myocarditis, coronary heart disease, and COPD.

[0206] According to embodiments of the present invention, the drug has the effect of promoting blood circulation and removing blood stasis. The drug of embodiments of the present invention also promotes joint mobility and relieves muscle soreness.

[0207] According to embodiments of the present invention, this drug is used to improve metabolism and hormone secretion. The drug of the embodiments of the present invention has the effect of lowering blood lipids, and when combined with appropriate diet and / or exercise, it can aid in weight loss. In clinical trials, the powder was taken at a dose of 20 grams, 1-2 times daily, and blood lipids were significantly reduced after one week of treatment.

[0208] According to embodiments of the present invention, this drug is used to regulate blood circulation, and is particularly effective in treating migraines. In clinical trials, the powder was taken at a dose of 20g, 1-2 times daily, and after taking the medication, with normal nutrition and rest, the migraines completely disappeared.

[0209] Human food trial

[0210] Experimental objective: To test the efficacy of the composition; to test the efficacy of the formula composed of the following principles: warming the interior and regulating qi, removing blood stasis, promoting blood circulation (such as angelica), dried ginger, licorice, dispersing herbs, and kidney-tonifying herbs in antiviral, cardiopulmonary function enhancement, blood circulation promotion and blood stasis removal, qi and blood circulation improvement, physical function enhancement, and antidepressant effects.

[0211] The listed experimental data covers a time span from May 2018 to May 2023.

[0212] Example 1

[0213] Basic formula:

[0214] 9g of Citrus aurantium, 13g of Paeonia suffruticosa, 7g of dried ginger, 9g of Glycyrrhiza uralensis, 9g of Angelica sinensis, 7g of Ephedra sinica, and 7g of Cornus officinalis;

[0215] Decoction recipe:

[0216] Aconite 9g, Citrus aurantium 7g, Paeonia suffruticosa 13g, Panax notoginseng 3g, dried ginger 7g, licorice 9g, Angelica sinensis 9g, Bupleurum chinense 7g, Ephedra sinica 7g, Platycladus orientalis seed 7g, Cornus officinalis 7g;

[0217] Powder formulation

[0218] B. Suitable for patients without underlying diseases;

[0219] 9g of Citrus aurantium, 13g of Paeonia suffruticosa root bark, 7g of dried ginger, 9g of licorice root, 9g of Angelica sinensis root, and 7g of Bupleurum chinense root.

[0220] Ephedra 7g, Platycladus orientalis seed 7g, Cornus officinalis 7g;

[0221] Example 2

[0222] Decoction recipe:

[0223] Aconite 7g, Sichuan pepper 7g, white peony root 13g, platycodon root 7g, dried ginger 7g, licorice root 9g, angelica root 9g, mulberry leaf 7g, sesame 7g, polygala root 7g, psoralea fruit 7g;

[0224] Powder formulation:

[0225] B. Suitable for patients without underlying diseases;

[0226] Sichuan pepper 9g, white peony root 13g, dried ginger 7g, licorice root 9g, angelica root 9g, mulberry leaf 7g, sesame 7g, polygala root 7g, psoralea fruit 7g

[0227] Example 3

[0228] Basic formula:

[0229] Aconite 9g, Liquidambar resin 7g, Alpinia officinarum 7g, Licorice 9g, Angelica sinensis 9g, Perilla frutescens 7g, Alpinia oxyphylla 7g;

[0230] Decoction recipe:

[0231] Aconite 9g, Curcuma longa 7g, Liquidambar formosana resin 7g, Panax notoginseng 5g, Alpinia officinarum 7g, Glycyrrhiza uralensis 9g, Angelica sinensis 9g, Perilla frutescens 7g, Prunella vulgaris 7g, Albizia julibrissin bark 7g, Alpinia oxyphylla 7g;

[0232] Example 4

[0233] Decoction recipe:

[0234] Aconite 7g, Magnolia officinalis 7g, Dragon's blood 7g, Vaccaria segetalis 7g, Dried ginger 7g, Licorice 9g, Angelica sinensis 9g, Schizonepeta tenuifolia 7g, Lobelia chinensis 9g, Ziziphus jujuba var. spinosa 7g, Rosa laevigata 7g;

[0235] Powder formulation:

[0236] B. Suitable for patients without underlying diseases;

[0237] Magnolia officinalis 9g, dragon's blood 7g, dried ginger 7g, licorice 9g, angelica sinensis 9g, lobelia chinensis 7g, schizonepeta tenuifolia 7g, jujube seed 7g, rosehip 7g;

[0238] Example 5

[0239] Decoction recipe:

[0240] Aconite 7g, Ephedra 7g, Sophora japonica bark 13g, Platycodon grandiflorus 7g, Dried ginger 7g, Licorice 9g, Angelica sinensis 9g, Notopterygium incisum 7g, Forsythia suspensa 7g, Albizia julibrissin flower 7g, Morinda officinalis 7g;

[0241] Powder formulation:

[0242] B. Suitable for patients without underlying diseases;

[0243] Ephedra 9g, Sophora japonica bark 13g, dried ginger 7g, licorice 9g, angelica sinensis 9g, forsythia 7g, notopterygium incisum 7g, albizia julibrissin flower 7g, morinda officinalis 7g;

[0244] Example 6

[0245] Decoction recipe:

[0246] 7g of Aconitum carmichaelii, 7g of Piper kadsura, 13g of Clematis chinensis, 7g of Vaccaria segetalis, 7g of dried ginger, 9g of licorice, 9g of Angelica sinensis, 7g of Schizonepeta tenuifolia, 7g of Phellodendron chinense, 7g of Polygonum multiflorum, and 7g of Dioscorea septum.

[0247] Powder formulation:

[0248] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0249] Aconite 9g, Clematis armandii 13g, dried ginger 7g, licorice 9g, angelica sinensis 9g, Schizonepeta tenuifolia spike 7g, Phellodendron chinense 7g, Polygonum multiflorum vine 7g, and septum septum 7g.

[0250] B. Suitable for patients without underlying diseases;

[0251] Example 7

[0252] Decoction recipe:

[0253] 7g of Aconitum carmichaelii, 7g of Piper cubeba, 13g of Cercis chinensis bark, 7g of Vaccaria segetalis, 7g of dried ginger, 9g of Glycyrrhiza uralensis, 9g of Dipsacus asper, 7g of Notopterygium incisum, 7g of Houttuynia cordata, 7g of Platycladus orientalis leaf, and 7g of Psoralea corylifolia.

[0254] Powder formulation:

[0255] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0256] Aconite root 9g, Bauhinia bark 13g, dried ginger 7g, licorice root 9g, Sichuan teasel root 9g, Notopterygium root 7g, Houttuynia cordata 7g, Platycladus orientalis leaf 7g, Psoralea corylifolia 7g;

[0257] B. Suitable for patients without underlying diseases;

[0258] 9g of cubeb, 13g of Bauhinia bark, 7g of dried ginger, 9g of licorice root, 9g of Dipsacus asper, 7g of Notopterygium root, 7g of Houttuynia cordata, 7g of Platycladus orientalis leaf, and 7g of Psoralea corylifolia.

[0259] Example 8:

[0260] Decoction formula

[0261] Aconite 7g, Sichuan costus root 7g, Gleditsia sinensis 10g, Platycodon grandiflorus 9g, Dried ginger 7g, Licorice root 9g, Angelica sinensis 9g, Asarum 5g, Fagopyrum dibotrys 7g, Fenugreek 7g, Poria cocos 7g;

[0262] Powder formulation:

[0263] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0264] Aconite 9g, Gleditsia sinensis 10g, Platycodon grandiflorus 7g, Dried ginger 7g, Licorice 9g, Angelica sinensis 9g, Asarum 5g, Fagopyrum dibotrys 7g, Trigonella foenum-graecum 7g, Poria cocos 7g;

[0265] Example 9:

[0266] Basic formula:

[0267] Aconite 9g, leech 3g, Panax notoginseng 3g, dried ginger 7g, licorice 9g, angelica 9g, centipeda minima 7g, Alpinia oxyphylla 7g;

[0268] Example 10

[0269] Basic formula:

[0270] Aconite 9g, Salvia miltiorrhiza 13g, Dried ginger 7g, Licorice 9g, Angelica sinensis 9g, Elsholtzia ciliata 7g, Cuscuta chinensis 7g;

[0271] Powder formulation:

[0272] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0273] Aconite 9g, Salvia miltiorrhiza 13g, Dried ginger 7g, Licorice 9g, Angelica sinensis 9g, Mosla chinensis 7g, Cuscuta chinensis 7g, Bupleurum chinense 7g, Jujube 7g;

[0274] B. Suitable for patients without underlying diseases;

[0275] Chuanxiong 9g, Danshen 13g, dried ginger 7g, licorice 9g, angelica 9g, xiangru 7g, dodder seed 7g, bupleurum 7g, jujube 7g;

[0276] Example 11

[0277] Decoction recipe:

[0278] Aconite 9g, Citrus reticulata peel 7g, Corydalis yanhusuo 10g, Aster tataricus 9g, Zingiber officinale 7g, Glycyrrhiza uralensis 9g, Angelica sinensis 9g, Saposhnikovia divaricata 7g, Cornus officinalis 7g, Vitex trifolia 7g, Pearl powder 5g;

[0279] Powder formulation:

[0280] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0281] Aconite 9g, Corydalis 10g, Dried Ginger 7g, Licorice 9g, Angelica sinensis 9g, Saposhnikovia divaricata 7g, Cornus officinalis 7g, Vitex trifolia 7g, Pearl Powder 5g;

[0282] Example 12

[0283] Powder formulation:

[0284] A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants).

[0285] Aconite 9g, Achyranthes bidentata 13g, Dried ginger 7g, Licorice 9g, Angelica pubescens 9g, Cinnamon twig 7g, Astragalus membranaceus 7g, Ajuga decumbens 9g, Poria cocos 7g;

[0286] Example 13

[0287] Powder formulation

[0288] B. Suitable for patients without underlying diseases;

[0289] 9g of dried tangerine peel, 15g of chicken blood vine, 7g of dried ginger, 9g of licorice root, 9g of angelica root, 7g of schizonepeta spike, 7g of cornus officinalis, 7g of honeysuckle vine, and 7g of oyster shell;

[0290] Comparative Example 1

[0291] The difference between this comparative example and Example 1 is that Atractylodes macrocephala is used instead of Angelica sinensis. The specific formula is as follows:

[0292] Aconite root 9g, Moutan bark 13g, Dried ginger 7g, Licorice root 9g, Atractylodes macrocephala 9g, Mosla chinensis 7g, Rosa laevigata 7g;

[0293] Comparative Example 2

[0294] This comparative example differs from Example 1 in that it lacks a blood-activating and stasis-removing drug; the specific formula is as follows:

[0295] Aconite 9g, dried ginger 7g, licorice 9g, angelica 9g, teasel root 9g, sesame 7g, rosehip 7g;

[0296] Comparative Example 3

[0297] The difference between this comparative example and Example 1 is that Astragalus membranaceus is used instead of Angelica sinensis. The specific formula is as follows:

[0298] Aconite root 9g, Moutan bark 13g, Dried ginger 7g, Licorice root 9g, Astragalus root 9g, Mosla herb 7g, Rosa laevigata fruit 7g;

[0299] Experimental subjects:

[0300] Patient A, female, 50 years old, about 163 cm tall, weighing about 55 kg, frequently catches colds.

[0301] Patient B, male, 69 years old, approximately 175 cm tall, weighing approximately 83 kg, has myocarditis;

[0302] Patient C, female, 49 years old, approximately 165 cm tall and weighing approximately 56 kg, was infected with COVID-19;

[0303] Patient D, male, 70 years old, about 175 cm tall, weighing about 83 kg, suffers from avascular necrosis of the femoral head and pain.

[0304] Patient E, male, 79 years old, approximately 180 cm tall, weighing approximately 79 kg, with Parkinson's disease, infected with COVID-19 Omeprón;

[0305] Patient F, female, 52 years old, about 165 cm tall, about 55 kg, with eczema (herpes virus infection);

[0306] Patient G, female, 52 years old, about 165 cm tall and weighing about 55 kg, suffers from sequelae of COVID-19, including chest tightness, shortness of breath, decreased physical strength, and decline in bodily functions.

[0307] Patient H, female, 51 years old, approximately 165 cm tall, weighing approximately 55 kg, has mental health issues, including depression;

[0308] Patient I, female, 69 years old, about 170 cm tall, weighing about 60 kg, has sequelae of COVID-19 and COPD.

[0309] Patient J, female, 26 years old, approximately 175 cm tall and weighing approximately 65 kg, was infected with COVID-19 in Omeprón.

[0310] Patient K, male, 27 years old, approximately 185 cm tall and weighing approximately 95 kg, was infected with COVID-19 in Omeprón.

[0311] Patient L, male, 58 years old, approximately 170 cm tall and weighing approximately 75 kg, was infected with COVID-19 in Omeprón.

[0312] Patient M, male, 27 years old, approximately 175 cm tall and weighing approximately 75 kg, was infected with COVID-19 in Omeprón.

[0313] Patient N, male, 57 years old, approximately 175 cm tall and weighing approximately 75 kg, was infected with COVID-19 in Omeprón.

[0314] Patient O, female, 52 years old, approximately 165 cm tall and weighing approximately 55 kg, was infected with COVID-19 in Omeprón.

[0315] Patient P, male, 28 years old, approximately 185 cm tall, weighing approximately 95 kg, suffers from allergic rhinitis and recurrent colds;

[0316] Patient Q, female, 50 years old, approximately 165 cm tall, weighing approximately 55 kg, has allergies;

[0317] Patient R, female, 51 years old, approximately 160 cm tall, weighing approximately 55 kg, with allergies;

[0318] Patient S, female, 50 years old, about 165 cm tall, weighing about 55 kg, suffers from migraines and muscle and joint strain;

[0319] Patient T, female, 77 years old, about 150 cm tall, weighing about 60 kg, with a history of hyperglycemia, a kidney transplant patient, and sequelae of COVID-19;

[0320] Patient U, male, 79 years old, about 175 cm tall and weighing about 73 kg, with a history of hyperglycemia and sequelae of cerebral infarction;

[0321] Patient V, male, 66 years old, approximately 175 cm tall and weighing approximately 75 kg, was infected with COVID-19 in Omeprón.

[0322] Patient W, female, 47 years old, about 155 cm tall and weighing about 50 kg, has knee pain and Omega-Jon infection.

[0323] The statistics for the above patients are as follows:

[0324] Table 1. Statistics on the number of patients

[0325] age 18-30 years old 31-50 years old 51-80 years old total quantity 4 people 5 people 14 people 23 people Underlying diseases none none 6 people 6 people No underlying diseases 4 5 8 17 people

[0326] Administration method

[0327] The combination is available in decoction and powder form. The antiviral treatment combination is taken with protein, such as by mixing with an egg or by adding protein powder; the basic formula is also administered in powder form.

[0328] Other benefits, such as improving cardiopulmonary function, promoting blood circulation, regulating qi and blood, enhancing physical function, and combating depression, do not require the addition of protein when taken.

[0329] Table 2. Corresponding medication methods for each disease.

[0330]

[0331]

[0332] Considering the high value and taste of leeches and Panax notoginseng in Example 9, leeches and Panax notoginseng were powdered, encapsulated, and taken orally in combination with other medications.

[0333] In accordance with the above administration method, young people under 50 years of age without underlying diseases infected with the novel coronavirus (C, K, M, N, V) should take mild dosage forms, such as the basic decoction formula 1 and powder formulas 1B, 2B, 3B, and 4B of the compositions in Examples 1-9.

[0334] The aforementioned patients E, J, L, N, O, and G, I, T who had underlying medical conditions and were infected with COVID-19 took relatively potent dosage forms, such as the decoction and dosage form A of the compositions in Examples 1-9.

[0335] Patients G, O, and T took the medication compared to Comparative Examples 1-3. Comparative Examples 1 and 3 used Astragalus and Atractylodes macrocephala instead of Angelica sinensis, and the therapeutic effect was insufficient and did not achieve the antiviral effect. Comparative Example 2, due to the lack of blood-activating and stasis-removing drugs, although it had some effect in improving bodily functions, it caused symptoms of dry mouth and bitter taste, indicating that the excretion was ineffective and the side effects were too great.

[0336] Table 3 Experimental Results

[0337]

[0338]

[0339] The results in the table above show that the formulation in the example has a good effect on fighting the novel coronavirus. Patient C took 20 days of medication before achieving clinical cure, which may be because Patient C was physically weak.

[0340] The positive significance of the formulation in the treatment of COVID-19 in this application embodiment is that it enhances bodily functions, increases the conversion rate of immune albumin in the body, alleviates symptoms, and for patients with underlying diseases, it can prevent the formation of blood clots and the occurrence of complications. Clinical observation showed that patients did not experience severe inflammation or severe immune response symptoms, such as a "knife-like" throat, high fever >38°C, or lower back pain, during the medication period.

[0341] In Comparative Examples 1 and 3, the formulas replaced Angelica sinensis with Astragalus membranaceus and Atractylodes macrocephala, respectively, and did not show any efficacy against the novel coronavirus. Astragalus membranaceus and Atractylodes macrocephala have weak efficacy, so they had no effect. In Comparative Example 2, the formula lacked a blood-activating and stasis-removing herb. Although Angelica sinensis and Dipsacus asper had a strong blood-activating and blood-generating effect, symptoms of dry mouth and bitter taste appeared after taking it, indicating that the side effects were significant and there was a phenomenon of excessive heat in the liver and gallbladder and poor blood circulation.

[0342] Following the above administration method, Examples 1-13 were administered to the remaining patients, and the results are shown in Table 4 below:

[0343] Table 4 Experimental Results

[0344]

[0345]

[0346]

[0347] The above description is merely a preferred embodiment of this application and an explanation of the technical principles employed. Those skilled in the art should understand that the scope of the invention involved in this application is not limited to technical solutions formed by specific combinations of the above-described technical features, but should also cover other technical solutions formed by arbitrary combinations of the above-described technical features or their equivalents without departing from the inventive concept. For example, technical solutions formed by substituting the above features with (but not limited to) technical features with similar functions disclosed in this application.

Claims

1. A composition characterized in that, include: Aconite or other qi-regulating components, wherein the other qi-regulating components are selected from Citrus aurantium, Melia toosendan, Magnolia officinalis, Ficus pumila, Citrus medica, Curcuma longa, Ephedra sinica, Liquidambar formosana, Piper kadsura, Ephedra sinica, Cinnamomum cassia, Ligusticum chuanxiong, Amomum villosum, Citrus reticulata peel, Cinnamomum cassia, Citrus reticulata peel, Aucklandia lappa, Citrus aurantium, Curcuma zedoaria, Mustard seed, Lindera strychnifolia, Zanthoxylum bungeanum or Citrus reticulata peel; The blood-activating and stasis-removing components are selected from one or two of the following: Vaccaria segetalis, Aster tataricus, Paeonia lactiflora, Gleditsia sinensis, Clematis chinensis, Paeonia suffruticosa, Panax notoginseng, Liquidambar formosana resin, Sophora japonica bark, Dragon's blood, Platycodon grandiflorus, Cercis chinensis bark, Hirudo medicinalis, Salvia miltiorrhiza, Tussilago farfara, Prunus persica kernel, Paeonia lactiflora, Prunus armeniaca, Hedyotis diffusa, Sparganium stoloniferum, Carthamus tinctorius, Boswellia carterii, Commiphora myrrha, Rubia cordifolia, Spatholobus suberectus, Corydalis yanhusuo, Achyranthes bidentata, Rhodiola rosea, Onion, and Rose. The component for warming the middle energizer, dispelling cold, restoring yang, and strengthening the spleen is selected from dried ginger, sand ginger, galangal, or turmeric. Licorice; The blood-activating and blood-generating components are selected from one or two of Angelica sinensis, Angelica pubescens, Drynaria fortunei, Acanthopanax senticosus, and Dipsacus asper. The components for dispersing wind-cold are selected from cinnamon twig, asarum, ephedra, sesame, perilla, perilla stem, schizonepeta, schizonepeta spike, notopterygium root, angelica root, dried ginger, centipeda grass, garlic, allium macrostemon, magnolia flower or saposhnikovia root; The kidney-tonifying component is selected from Rosa laevigata, Cuscuta chinensis, Allium tuberosum seed, Alpinia septum, Astragalus membranaceus, Rubus idaeus, Cornus officinalis, Rosa rugosa, Morinda officinalis, Cynomorium songaricum, Epimedium brevicornu, Trigonella foenum-graecum, Alpinia oxyphylla, Mantis religiosa ootheca, Cuttlebone, Schisandra chinensis, Curculigo orchioides, Psoralea corylifolia, or Morus alba.

2. The composition of claim 1, wherein, include: 7-13 parts by weight of Aconitum carmichaelii or other qi-regulating components; 7-18 parts by weight of the blood-activating and stasis-removing components; 7-12 parts by weight of the warming and dispelling cold, restoring yang and unblocking the meridians component; 7-12 parts by weight of licorice; 7-12 parts by weight of blood-activating and blood-generating components; 5-9 parts by weight of the dispersing wind-cold component; 5-9 parts by weight of the kidney-strengthening component.

3. The composition of claim 1, wherein, include: The calming component is selected from oyster, pearl powder, amber, arborvitae leaf, arborvitae seed, jujube seed, mimosa flower, polygala, jujube, longan, lily, poria cocos, fleeceflower stem, or mimosa bark. and / or The heat-clearing and detoxifying components are selected from Bupleurum chinense, Buddleja officinalis, Hedyotis diffusa, mulberry leaf, Allium macrostemon, dandelion, Portulaca oleracea, Forsythia suspensa, Scutellaria baicalensis, Phellodendron chinense, Coptis chinensis, Prunella vulgaris, Uncaria rhynchophylla, Forsythia suspensa, Houttuynia cordata, Fritillaria cirrhosa, Physalis alkekengi, Lithospermum erythrorhizon, Patrinia scabiosaefolia, Gardenia jasminoides, Cassia tora, Lonicera japonica, Viola yedoensis, Tropaeolum majus, Vitex trifolia, Isatis indigotica, Fagopyrum dibotrys, Lonicera japonica, Scutellaria barbata, Lobelia chinensis, Cremastra appendiculata, Ajuga decumbens, Belamcanda chinensis, Isatis indigotica, Andrographis paniculata, Phellodendron chinense, Eriobotrya japonica, Polygonum cuspidatum, Lonicera japonica, Chrysanthemum morifolium, Chicorydalis yanhusuo, Imperata cylindrica, Phragmites communis, Cirsium japonicum, Cirsium setosum, or Silybum marianum.

4. The composition of claim 3, wherein, include: 7-13 parts by weight of Aconitum carmichaelii or other qi-regulating components; 7-18 parts by weight of the blood-activating and stasis-removing components; 7-12 parts by weight of warming the middle jiao, dispelling cold, restoring yang, and strengthening the spleen components; 7-12 parts by weight of licorice; 7-12 parts by weight of blood-activating and blood-generating components; 5-9 parts by weight of the dispersing wind-cold component; 5-9 parts by weight of the kidney-strengthening component; 5-9 parts by weight of the calming component; and / or 7-12 parts by weight of the heat-clearing and detoxifying component.

5. The composition of claim 3, wherein 7-13 parts by weight of Fuzi or other Qi-regulating components, 7-18 parts by weight of Danshen, 7-12 parts by weight of Ganjiang, 7-12 parts by weight of Gancao, 7-12 parts by weight of Dangui, 7-12 parts by weight of Chaihu, 5-9 parts by weight of Mahuang, 5-9 parts by weight of Baiziren, 5-9 parts by weight of Shanzhu Or, basic formula: Fuzi 7g-12g (or Chaiqianzi 7g-13g), Mudanpi 7g-15g, Ganjiang 7g-12g, Gancao 7g-12g, Dangui 7g-12g, Mahuang 5g-9g, Shanzhu 5g-9g Or, decoction formula: Fuzi 7g-12g, Chaiqianzi 7g-13g, Mudanpi 9g-15g, Sanqi 3g-13g, Ganjiang 7g-12g, Gancao 7g-12g, Dangui 7g-12g, Chaihu 7g-12g, Mahuang 5g-9g, Baiziren 5g-9g, Shanzhu 5g-9g Or, powder formula: A, suitable for patients with underlying diseases (not including acute onset of hypertension, no data on patients with organ transplantation) Fuzi 7g-12g, Mudanpi 9g-16g, Ganjiang 7g-12g, Gancao 7g-12g, Dangui 7g-12g, Chaihu 7g-12g, Mahuang 5g-9g, Baiziren 5g-9g, Shanzhu 5g-9g Or, B, suitable for patients without underlying diseases Chaiqianzi 7g-13g, Mudanpi 9g-16g, Ganjiang 7g-12g, Gancao 7g-12g, Dangui 7g-12g, Chaihu 7g-12g, Mahuang 5g-9g, Baiziren 5g-9g, Shanzhu 5g-9g Or, basic formula: Fuzi 7g-12g (or Chaiqianzi 7g-13g), Baishao 9g-15g, Ganjiang 7g-12g, Gancao 7g-12g, Dangui 7g-12g, Xiangru 5g-9g, Buguzhi 5g-9g Or, decoction formula: Fuzi 7g-12g, Chaiqianzi 7g-13g, Baishao 9g-15g, Sanqi 3g-13g, Ganjiang 7g-12g, Gancao 7g-12g, Dangui 7g-12g, Sangye 7g-12g, Xiangru 5g-9g, Juanshi 5g-9g, Buguzhi 5g-9g Or, powder formula: A, suitable for patients with underlying diseases (not including acute onset of hypertension, no data on patients with organ transplantation) Fuzi 7g-12g, Baishao 9g-16g, Ganjiang 7g-12g, Gancao 7g-12g, Dangui 7g-12g, Sangye 7g-12g, Xiangru 5g-9g, Juanshi 5g-9g, Buguzhi 5g-9g Or, B, suitable for patients without underlying diseases Chaiqianzi 7g-13g, Baishao 9g-16g, Ganjiang 7g-12g, Gancao 7g-12g, Dangui 7g-12g, Sangye 7g-12g, Xiangru 5g-9g, Juanshi 5g-9g, Buguzhi 5g-9g Or, basic formula: Fuzi 7-12g, Wulingzhi 3-10g, Gancao 7-12g, Danggui 7-12g, Xiasu 7-12g, Gegen 7-12g, Baizhu 7-12g, Yiren 5-9g Or, decoction formula: Fuzi 7-12g, Wulingzhi 3-10g, Gancao 7-12g, Danggui 7-12g, Xiasu 7-12g, Gegen 7-12g, Baizhu 7-12g, Yiren 5-9g Or, powder formula: A, suitable for patients with underlying diseases (not including acute onset of hypertension, no data on patients with organ transplantation) Fuzi 7-12g, Wulingzhi 3-10g, Gancao 7-12g, Danggui 7-12g, Xiasu 7-12g, Gegen 7-12g, Baizhu 7-12g, Yiren 5-9g Or, B, suitable for patients without underlying diseases Fuzi 7-12g, Wulingzhi 3-10g, Gancao 7-12g, Danggui 7-12g, Xiasu 7-12g, Gegen 7-12g, Baizhu 7-12g, Yiren 5-9g Or, basic formula: Fuzi 7-12g (or Houpu 7-13g), Xuejie 3-10g, Ganjiang 7-12g, Gancao 7-12g, Danggui 7-12g, Jingjie 5-9g, Jinyingzi 5-9g Or, decoction formula: Fuzi 7-12g, Houpu 5-9g, Xuejie 3-10g, Wangbuliuying 7-9g, Ganjiang 7-12g, Gancao 7-12g, Danggui 7-12g, Jingjie 5-9g, Banlangen 7-12g, Suanzaoren 5-9g, Jinyingzi 5-9g Or, powder formula: A, suitable for patients with underlying diseases (not including acute onset of hypertension, no data on patients with organ transplantation) Fuzi 7-12g, Xuejie 3-10g, Ganjiang 7-12g, Gancao 7-12g, Danggui 7-12g, Banlangen 7-12g, Jingjie 5-9g, Suanzaoren 5-9g, Jinyingzi 5-9g Or, B, suitable for patients without underlying diseases Houpu 7-13g, Xuejie 3-10g, Ganjiang 7-12g, Gancao 7-12g, Danggui 7-12g, Banlangen 7-12g, Jingjie 5-9g, Suanzaoren 5-9g, Jinyingzi 5-9g Or, basic formula: Fuzi 7-12g (or Mahuang 7-13g), Huaiqiangpi 7-16g (or Jiegeng 7-16g), Ganjiang 7-12g, Gancao 7-12g, Danggui 7-12g, Qianghuo 5-9g, Bajitian 5-9g Or, decoction formula: Fuzi 7g-12g, Huangliangpi 9g-16g, Gancao 7g-12g, Danggui 7g-12g, Lianqiao 7g-12g, Qianghuo 5g-9g, Hehuanhua 5g-9g, Bajitian 5g-9g; Or, powder formula: A, suitable for patients with underlying diseases (not including acute onset of hypertension, no data on patients with organ transplantation) Fuzi 7g-12g, Huangliangpi 9g-16g, Gancao 7g-12g, Danggui 7g-12g, Lianqiao 7g-12g, Qianghuo 5g-9g, Hehuanhua 5g-9g, Bajitian 5g-9g; Or, B, suitable for patients without underlying diseases; Fuzi 7g-12g, Huangliangpi 9g-16g, Gancao 7g-12g, Danggui 7g-12g, Lianqiao 7g-12g, Qianghuo 5g-9g, Hehuanhua 5g-9g, Bajitian 5g-9g; Or, basic formula: Fuzi 7g-12g (or Huifengteng 7g-13g), Tougucao 7g-16g (or Wangbuluixing 7g-16g), Gancao 7g-12g, Danggui 7g-12g, Jingjiewei 5g-9g, Fenchengmu 5g-9g; Or, decoction formula: Fuzi 7g-12g, Huifengteng 7-13g, Tougucao 7g-16g, Wangbuluixing 7g-16g, Gancao 7g-12g, Danggui 7g-12g, Jingjiewei 5g-9g, Huangbai 7g-12g, Shouwuteng 5g-9g, Fenchengmu 5g-9g; Or, powder formula: A, suitable for patients with underlying diseases (not including acute onset of hypertension, no data on patients with organ transplantation) Fuzi 7g-12g, Tougucao 7g-16g, Gancao 7g-12g, Danggui 7g-12g, Jingjiewei 5g-9g, Huangbai 7g-12g, Shouwuteng 5g-9g, Fenchengmu 5g-9g; Or, B, suitable for patients without underlying diseases; Huifengteng 7g-13g, Tougucao 7g-16g, Gancao 7g-12g, Danggui 7g-12g, Jingjiewei 5g-9g, Huangbai 7g-12g, Shouwuteng 5g-9g, Fenchengmu 5g-9g; Or, basic formula: Fuzi 7g-12g (or Bichengqie 7g-13g), Ziqingpi 7g-16g, Gancao 7g-12g, Chuanxuduan 7g-12g, Qianghuo 5g-9g, Buguzhi 5g-9g; Or, decoction formula: Fuzi 7g-12g, Bichengqie 7-13g, Ziqingpi 7g-16g, Wangbuluixing 7g-16g, Gancao 7g-12g, Chuanxuduan 7g-12g, Qianghuo 5g-9g, Yuxingcao 7g-12g, Cebaiye 5g-9g, Buguzhi 5g-9g; Or, powder formula: A, suitable for patients with underlying diseases (not including acute onset of hypertension, no data on patients with organ transplantation) Fuzi 7-12g, Zaojia 7-16g, Ganjiang 7-12g, Ganzao 7-12g, Danggui 7-12g, Qianghuo 5-9g, Yuxingcao 7-12g, Cebai 5-9g, Buguzhi 5-9g; Or, B, suitable for patients without underlying diseases; Fuzi 7-12g, Zaojia 7-16g, Ganjiang 7-12g, Ganzao 7-12g, Danggui 7-12g, Qianghuo 5-9g, Yuxingcao 7-12g, Cebai 5-9g, Buguzhi 5-9g; Or, basic formula: Fuzi 7-12g (or Lulutong 7-13g), Shaoyi 5-13g, Ganjiang 7-12g, Ganzao 7-12g, Danggui 7-12g, Xixian 5-9g, Huluba 5-9g; Or, decoction formula: Fuzi 7-12g, Lulutong 7-13g, Zaojia 7-16g, Jiegeng 7-16g, Ganjiang 7-12g, Ganzao 7-12g, Danggui 7-12g, Xixian 5-9g, Jinqiao 7-12g, Huluba 5-9g, Fushen 5-9g; Or, powder formula: A, suitable for patients with underlying diseases (not including acute onset of hypertension, no data on patients with organ transplantation) Fuzi 7-12g, Zaojia 7-16g, Jiegeng 7-16g, Ganjiang 7-12g, Ganzao 7-12g, Danggui 7-12g, Xixian 5-9g, Jinqiao 7-12g, Huluba 5-9g, Fushen 5-9g; Or, B, suitable for patients without underlying diseases; Lulutong 7-13g, Zaojia 7-16g, Jiegeng 7-16g, Ganjiang 7-12g, Ganzao 7-12g, Danggui 7-12g, Xixian 5-9g, Jinqiao 7-12g, Huluba 5-9g, Fushen 5-9g; Or, basic formula: Fuzi 7-12g (or Lulutong 7-13g), Shuizhi 1-13g, Sanqi 3-13g, Ganjiang 7-12g, Ganzao 7-12g, Danggui 7-12g, Ebusichao 5-9g, Yizhi 5-9g; Or, decoction formula: Fuzi 7-12g, Lulutong 7-13g, Shuizhi 1-13g, Sanqi 3-13g, Ganjiang 7-12g, Ganzao 7-12g, Danggui 7-12g, Ebusichao 7-12g, Zhizi 7-12g, Yizhi 5-9g, Baizi 5-9g; Or, powder formula: A, suitable for patients with underlying diseases (not including acute onset of hypertension, no data on patients with organ transplantation) Fuzi 7-12g, Shuizhi 1-13g, Sanqi 3-13g, Ganjiang 7-12g, Ganzao 7-12g, Danggui 7-12g, Ebusichao 7-12g, Zhizi 7-12g, Yizhi 5-9g, Baizi 5-9g; Or, B, suitable for patients without underlying diseases; 7g-13g of *Luffa cylindrica*, 1g-13g of leech, 3g-13g of *Panax notoginseng*, 7g-12g of dried ginger, 7g-12g of licorice root, 7g-12g of angelica sinensis, 7g-12g of *Centipeda minima*, 7g-12g of gardenia, 5g-9g of *Alpinia oxyphylla*, and 5g-9g of *Platycladus orientalis*. Or, the basic side: Aconite 7g-12g (or Ligusticum chuanxiong 7g-13g), Salvia miltiorrhiza 7g-16g, dried ginger 7g-12g, licorice 7g-12g, Angelica sinensis 7g-12g, Elsholtzia ciliata 5g-9g, Cuscuta chinensis 5g-9g; Alternatively, a decoction formula: Aconite 7g-12g, Ligusticum chuanxiong 7g-13g, Salvia miltiorrhiza 7g-16g, Peucedanum praeruptorum 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Elsholtzia ciliata 5g-9g, Cuscuta chinensis 5g-9g, Bupleurum chinense 7g-12g, Ziziphus jujuba 5g-9g; Alternatively, a powder formulation: A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants). Aconite 7g-12g, Salvia miltiorrhiza 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Elsholtzia ciliata 5g-9g, Cuscuta chinensis 5g-9g, Bupleurum chinense 7g-12g, Jujube 5g-9g; Alternatively, option B is suitable for patients without underlying medical conditions. Chuanxiong 7g-13g, Danshen 7g-16g, dried ginger 7g-12g, licorice 7g-12g, angelica 7g-12g, sesame 5g-9g, dodder seed 5g-9g, bupleurum 7g-12g, jujube 5g-9g; Or, the basic method, Aconite 7g-12g (or green tangerine peel 7g-13g), Corydalis 7g-16g, dried ginger 7g-12g, licorice 7g-12g, angelica 7g-12g, saposhnikovia 5g-9g, cornus 5g-9g; Alternatively, a decoction formula: Aconite 7g-12g, Citrus reticulata peel 7g-13g, Corydalis yanhusuo 7g-16g, Aster tataricus 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica sinensis 7g-12g, Saposhnikovia divaricata 5g-9g, Cornus officinalis 5g-9g, Vitex trifolia 7g-12g, Pearl powder 5g-9g; Alternatively, a powder formulation: A. Suitable for patients with underlying diseases (excluding patients in the acute phase of hypertension, and there is no data on patients who have received organ transplants). Aconite 7g-12g, Corydalis 7g-16g, Dried Ginger 7g-12g, Licorice 7g-12g, Angelica 7g-12g, Saposhnikovia 5g-9g, Cornus officinalis 5g-9g, Vitex trifolia 7g-12g, Pearl Powder 5g-9g; Alternatively, option B is suitable for patients without underlying medical conditions. Green tangerine peel 7g-13g, Corydalis rhizome 7g-16g, dried ginger 7g-12g, licorice root 7g-12g, angelica root 7g-12g, saposhnikovia root 5g-9g, cornus fruit 5g-9g, vitex fruit 7g-12g, pearl powder 5g-9g; Or, the basic side: Aconite 7g-12g (or Costus root 7g-13g), Achyranthes bidentata 7g-16g, Dried ginger 7g-12g, Licorice 7g-12g, Angelica pubescens 7g-12g, Cinnamon twig 5g-9g, Astragalus membranaceus 5g-9g; Alternatively, a decoction formula: Fuzi 7g-12g, Muxiang 7g-13g, Niuxi 7g-16g, Wangfuzi 7g-16g, Gancao 7g-12g, Duhuo 7g-12g, Guizhi 5g-9g, Sharenzi 5g-9g, Jingucao 7g-12g, Fushen 5g-9g Or, a powder formula: A. Suitable for patients with underlying diseases (not including acute onset of hypertension, no data on patients with organ transplants) Fuzi 7g-12g, Muxiang 7g-13g, Niuxi 7g-16g, Gancao 7g-12g, Duhuo 7g-12g, Guizhi 5g-9g, Sharenzi 5g-9g, Jingucao 7g-12g, Fushen 5g-9g Or, B. Suitable for patients without underlying diseases Muxiang 7g-13g, Niuxi 7g-16g, Gancao 7g-12g, Duhuo 7g-12g, Guizhi 5g-9g, Sharenzi 5g-9g, Jingucao 7g-12g, Fushen 5g-9g Or, a basic formula Fuzi 7g-12g (or Juzhi 7g-13g), Jixueteng 7g-16g, Gancao 7g-12g, Danggui 7g-12g, Jingjie 5g-9g, Shanzha 5g-9g Or, a decoction formula: Fuzi 7g-12g, Juzhi 7g-13g, Jixueteng 7g-16g, Honghua 7g-16g, Gancao 7g-12g, Danggui 7g-12g, Jingjie 5g-9g, Shanzha 5g-9g, Rendongteng 7g-12g, Muli 7g-12g Or, a powder formula: A. Suitable for patients with underlying diseases (not including acute onset of hypertension, no data on patients with organ transplants) Fuzi 7g-12g, Jixueteng 7g-16g, Gancao 7g-12g, Danggui 7g-12g, Jingjie 5g-9g, Shanzha 5g-9g, Rendongteng 7g-12g, Muli 7g-12g Or, B. Suitable for patients without underlying diseases Juzhi 7g-13g, Jixueteng 7g-16g, Gancao 7g-12g, Danggui 7g-12g, Jingjie 5g-9g, Shanzha 5g-9g, Rendongteng 7g-12g, Muli 7g-12g.

6. A medicament, characterized by comprising: Comprising: The composition of any one of claims 1-5.

7. The medicament according to claim 6, characterized in that, Further comprising adjuvants; Optionally, the dosage form of the medicament is selected from the group consisting of decoction, powder, injection, tablet, tincture or pill.

8. A combination drug, characterized in that, Comprising: The medicament of claim 6 or 7; Protein-containing substances selected from the group consisting of protein powder, eggs, lean meat.

9. Use of a composition according to any one of claims 1 to 5 for the manufacture of a medicament, characterized in that, The medicament is used for antiviral; Optionally, the virus is selected from the group consisting of coronavirus; Optionally, the virus is selected from the group consisting of novel coronavirus SARS-CoV-2.

10. Use according to claim 9, characterized in that, The medicament is used for anti-depression.

11. Use according to claim 9, characterized in that, The medicament is used for improving heart and lung function; Optionally, the medicament is used for preventing or treating myocarditis, chronic obstructive pulmonary disease and coronary heart disease.

12. Use according to claim 9, characterized in that, The medicament is used for preventing or treating muscle soreness and joint mobility.

13. Use according to claim 9, characterized in that, The medicament is used for improving body metabolism and hormone secretion.

14. Use according to claim 9, characterized in that, The medicament is used for regulating blood circulation; Optionally, the medicament is for the prevention or treatment of migraine.

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