An intelligent anorectal sustained-release drug delivery device

Abstract

This invention discloses an intelligent anorectal slow-release drug delivery device, relating to the field of drug delivery technology. It includes a drug delivery device, a dressing pad, and a drug release plug connected to the drug delivery device via a delivery tube. The drug release plug is positioned on the anal side of the dressing pad via a delivery tube that passes through it and is inserted into the anus. The drug delivery device delivers the medication to the drug release plug at regular intervals and in measured quantities via the delivery tube, and the medication is slowly released into the anus through micropores on the surface of the drug release plug, allowing the medication to exert its therapeutic effect continuously within the anus around the clock. The dressing pad includes an absorbent pad and a sponge cone. The absorbent pad absorbs leaked liquid from the anus to keep the perineum and buttocks dry and clean. The sponge cone conforms to the shape of the anus and perineum, with complementary concave and convex features, and a medication inlet is provided on the side that contacts the anus. This invention is simple, quick, and convenient to operate, with minimal pain. Patients can perform the procedure at home, avoiding the difficulties and inconveniences of hospital dressing changes, and saving costs and resources.

Description

Technical Field

[0001] This invention relates to the field of drug delivery technology, specifically to an intelligent anorectal sustained-release drug delivery device. Background Technology

[0002] Rectal dressing changes (including external application and intrarectal administration) are an important treatment for anorectal diseases and an essential part of postoperative care in anorectal surgery. Currently, clinical methods for rectal dressing changes largely follow traditional practices, including the following steps:

[0003] 1. Insert or inject the special medication (suppository, cream, gel, liquid, etc.) into the anus; if it is a postoperative dressing change (such as after hemorrhoid surgery), it may also be necessary to pack a strip of petroleum jelly gauze into the anus after inserting the medication;

[0004] 2. Apply the topical medication (such as ointment, cream, lotion, etc.) around the anus, then cover it with a dressing (such as gauze or special patch), and finally bandage it in place.

[0005] The above-mentioned dressing-changing methods have many drawbacks. They are not only cumbersome and crude in operation, but also cause significant irritation (including physical and chemical irritation) to the wound or lesion, often resulting in extreme pain for the patient and deterring them from using them. In addition, traditional dressing-changing methods also have the following disadvantages:

[0006] 1. Patients must go to the hospital once or more every day, which is not only difficult and inconvenient to commute, but also extremely time-consuming to queue at the outpatient clinic, affecting their normal work and work.

[0007] 2. Traditional intrarectal suppositories / injections and routine external dressings are generally "single-use" because patients easily expel the medication during defecation, and the external dressing also easily falls off, resulting in a short duration of efficacy. Furthermore, patients typically experience increased bowel movements after anorectal surgery (3-6 times per day is common, and more than 10 times per day is not uncommon), so even with repeated dressing changes, it is impossible to maintain the drug's effectiveness for an extended period.

[0008] 3. Traditional dressing changes for anal wounds or lesions typically involve first applying medication (such as ointment or cream) to a dressing like gauze, then covering the wound or lesion. It is then bandaged and secured. However, due to the anus's unique shape (located between the left and right buttocks, forming a narrow groove), the medication applied to the dressing is difficult to adhere closely to the wound or lesion; it is also more likely to slip off when standing or walking, thus hindering the full effectiveness of the medication. Summary of the Invention

[0009] The purpose of this invention is to provide an intelligent anorectal sustained-release drug delivery device, which solves the problems mentioned in the background art.

[0010] The present invention solves the above-mentioned technical problems through the following technical solution: the present invention includes a drug infusion device, a dressing change pad, and a drug release plug connected to the drug infusion device through a drug infusion tube;

[0011] The suppository is placed on the anal side of the dressing pad through a delivery tube that passes through the dressing pad and is inserted into the anus;

[0012] The infusion device delivers the drug solution to the drug release suppository at regular intervals and in a measured amount through the infusion tube, and then slowly releases it into the anus and rectum through the micropores on the surface of the suppository, so as to achieve the effect of the drug solution continuously exerting its therapeutic effect in the anus around the clock.

[0013] Preferably, the infusion device includes a base plate, on which an infusion bag that can be detached and installed is provided, and a micro-infusion pump that pumps out the drug solution in the infusion bag, wherein the micro-infusion pump is detachably connected to the infusion tubing;

[0014] The substrate is also provided with a control panel and a storage battery that are electrically connected to the micro-infusion pump;

[0015] The control panel can be pre-set with parameters according to the patient's condition, thereby controlling the infusion cycle, frequency, and start / stop of the micro-infusion pump in a timely and quantitative manner to transfer the medication in the infusion bag to the release plug through the infusion tubing.

[0016] Preferably, an infusion connector is installed on one side of the substrate, and the outlet of the infusion bag is sealed and inserted into the inlet of the infusion connector; the outlet of the infusion connector is connected to the inlet of the micro-infusion pump.

[0017] Preferably, the dressing change pad includes an absorbent pad and a sponge cone disposed on the absorbent pad. The absorbent pad is used to absorb liquid leaking from the anus to keep the perineum and buttocks dry and clean. The sponge cone conforms to the shape of the anus and perineum, with complementary concave and convex features.

[0018] Preferably, the side of the sponge cone that contacts the anus is provided with a drug delivery groove, in which topical medication can be released to achieve continuous, all-day application of the topical medication to the anal lesions or wounds.

[0019] Preferably, the drug-releasing suppository is made of a polymer material or a soft material, and includes a suppository body and an inner cavity disposed inside the suppository body. The micropores are connected to the inner cavity to enable the drug solution to be released to the outside through the micropores.

[0020] Preferably, the front end of the plug is in the shape of a smooth bullet, cone, sphere, or ellipsoid.

[0021] Preferably, the inner cavity of the plug is filled with a water-absorbing and water-retaining material.

[0022] Preferably, the side of the sponge cone is provided with multiple water guiding holes to guide the liquid overflowing from the anus to the bottom absorbent pad.

[0023] Preferably, the suppository is equipped with a temperature sensor or a drug concentration sensor to monitor the patient's anal temperature or drug concentration in real time, and to feed the monitoring data back to the infusion device in real time. Under the intelligent control of the control panel containing a microchip, the infusion time, cycle and frequency can be intelligently adjusted.

[0024] Preferably, the sponge cone has an installation chamber, and the installation chamber has a receiving through hole corresponding to the drug release suppository; the installation chamber is provided with a rubber thrust member, which is used to push the drug release suppository out of the sponge cone, and the upper end of the rubber thrust member is provided with a base plate, and the upper side of the base plate is provided with a soft sleeve connected to the sponge cone;

[0025] The bottom of the absorbent pad is provided with a bottom adhesive cloth, one end of which is fixedly connected to the absorbent pad, and the other areas are bonded to the absorbent pad. A pull rope is connected between the bottom adhesive cloth and the base plate.

[0026] By tearing off or re-attaching the bottom adhesive cloth, the pull rope is moved to extend or shorten the rubber thrust component, thereby causing the drug release plug to extend or retract.

[0027] Preferably, the rubber thrust member includes two symmetrically arranged bent rubber blocks, and an inclined rubber block is fixed to the inner side of the two bent rubber blocks. The upper end of the inclined rubber block is connected to the base plate, and the elastic coefficient of the bent rubber block is greater than that of the inclined rubber block.

[0028] Preferably, the receiving through hole is provided with colloid wiping blocks that can be moved laterally and a telescopic bladder that pushes the colloid wiping blocks outward when expanded. An elastic air bladder is provided on the bottom adhesive cloth, and the elastic air bladder and the telescopic bladder are connected by an air tube.

[0029] Preferably, the inner end of the colloid wiping block has a semi-circular cross-section, and the inner end of the colloid wiping block is provided with a multi-layered protrusion structure to achieve multiple close contacts with the outer surface of the drug-releasing suppository.

[0030] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0031] 1. Simple and easy to use: The dressing change method of this device is very simple and easy to use. Ordinary patients can master it with a little training. Therefore, this device can be easily completed by patients at home, avoiding the various difficulties and inconveniences of dressing changes in the hospital, and saving costs and resources.

[0032] 2. Minimal pain: The key steps for changing the dressing that the patient needs to master are only two: first, insert the "drug-releasing suppository" into the anus; second, place the topical ointment in the "medication tray" of the "drug-changing pad" and then place the "drug-changing pad" on the anus and perineum and stick it properly. Since the whole operation is extremely simple and can be done by oneself, there is no major stimulation from beginning to end, so the patient experiences almost no pain.

[0033] 3. Continuous and slow drug delivery: The infusion device, micro-infusion pump and drug release plug work closely together. Infusion parameters can be preset according to the patient's condition. Under the intelligent control of the control panel containing a microchip, the infusion time, cycle and frequency can be intelligently adjusted to achieve continuous and slow drug delivery and maximize the efficacy of the drug.

[0034] 4. Flexible and adaptable administration of intrarectal medications: The liquid component of external infusion bags is generally physiological saline, but other medications or combinations of medications (such as antibiotics, anti-inflammatory analgesics, anesthetics, mucosal protectants, hormones, etc.) can also be added to the infusion bag at the same time, depending on the doctor's decision based on the condition, allowing for flexibility.

[0035] 5. Combined with topical medication for internal and external treatment: While providing slow-release medication into the anus, the "dressing pad" of this invention is designed with an "anus-shaped sponge cone and its external medication application tray." The anus-shaped sponge cone is similar in shape to the anus and perineum, allowing for close contact with the area. The external medication application tray can hold different topical ointments or creams as needed. This design ensures that the medication remains in close contact with the anus and continuously acts on the lesion or wound, maximizing its efficacy and achieving a combined internal and external treatment effect.

[0036] 6. Saves patients' personal time and does not affect their work: Since the dressing change procedure is simple and easy to perform, patients can do it at home by themselves. Therefore, patients do not need to go to the hospital for dressing changes every day. This not only greatly saves commuting time, but also greatly saves time spent queuing for registration and waiting for dressing changes at the hospital, without affecting their work.

[0037] 7. Self-cleaning suppositories: Through the pneumatically driven colloidal wiping block and elastic airbag, the suppository automatically and thoroughly cleans the surface of dirt without hand contact during each removal and repositioning. When retracting, the wiping block is moved outward to avoid secondary contamination, and when extended, it scrapes bidirectionally again to ensure that the surface is basically clean before insertion into the anus, significantly reducing the risk of infection and patient psychological barriers. At the same time, the entire cleaning process can be completed in just a few seconds with one hand, greatly improving the hygiene, convenience and treatment compliance of long-term home care after anorectal surgery. Attached Figure Description

[0038] Figure 1 This is a three-dimensional structural diagram of Example 1;

[0039] Figure 2This is a three-dimensional structural diagram of the sponge cone and water guide hole in Example 1;

[0040] Figure 3 for Figure 1 A three-dimensional schematic diagram of the first structure of the drug delivery device;

[0041] Figure 4 for Figure 1 A schematic diagram of the second three-dimensional structure of the drug delivery device;

[0042] Figure 5 for Figure 1 A schematic diagram of the three-dimensional cross-section of the drug-releasing suppository;

[0043] Figure 6 This is a three-dimensional structural diagram of Example 2;

[0044] Figure 7 This is a schematic diagram of the structure of the drug-releasing suppository extending out of the dressing change pad in Example 2.

[0045] The numbers in the image represent:

[0046] 11-Cover plate; 12-Micro-infusion pump; 13-Base plate; 14-Infusion bag; 15-Fixing strap; 16-Infusion connector; 17-Control panel; 21-Absorbent pad; 22-Dosage tank; 23-Sponge cone; 24-Water guide hole; 3-Drug release plug; 30-Drug infusion tube; 31-Plug body; 32-Inner chamber; 33-Micropore; 34-Drug concentration sensor; 35-Soft sleeve; 36-Base plate; 37-Temperature sensor; 41-Bent rubber spring; 42-Inclined rubber spring; 43-Pull cord; 51-Bottom adhesive cloth; 52-Traction cloth; 61-Elastic airbag; 62-Trachea; 63-Expanding bladder; 64-Colloid rub block. Detailed Implementation

[0047] The above-mentioned and other technical features and advantages of the present invention will be described in more detail below with reference to the accompanying drawings. Example

[0048] This embodiment provides a technical solution: an intelligent anorectal sustained-release drug delivery device, such as... Figures 1 to 6 As shown, the system includes an infusion device, a suppository 3 for use with it, and a dressing pad. The suppository 3 is located on the inner side of the dressing pad. The suppository 3 is inserted into the patient's anus through an infusion tube that passes through the dressing pad. The infusion device and the suppository 3 are functionally connected through an infusion tube 30. The medication in the infusion device is delivered to the suppository 3 and then flows out, forming a complete, independent, and continuous anorectal care system that can be performed at home. It achieves multiple benefits, including being simple, easy to use, and minimally painful, and allowing for slow, continuous medication delivery as well as both internal and external treatment.

[0049] The infusion set has a rectangular, portable design, measuring approximately 120mm × 80mm × 40mm and weighing no more than 250g. It is easy for patients to attach to their waist belt or carry in a pocket. The infusion set includes a base plate 13, with a detachable infusion bag 14 on one side. The infusion bag 14 stores the patient's required medication (the medication can be a single or combined solution of physiological saline, antibiotics, anesthetics, mucosal protectants, hormones, etc., pre-prepared according to the doctor's orders). The infusion bag 14 is a disposable medical soft bag with a capacity of 50–300mL. The infusion bag 14 is secured by one or more fixing straps 15. When there is a single fixing strap 15, it is wider and can cover all or most of the infusion bag 14. When there are multiple fixing straps 15, they are narrower. The fixing straps 15 facilitate the disassembly and replacement of the infusion bag 14. An infusion connector 16 and a micro-infusion pump 12 are installed on one side of the base plate 13. The inlet end of the infusion connector 16 is sealed and plugged into the outlet of the infusion bag 14 to prevent leakage of the medicine. The outlet end of the infusion connector 16 is connected to the inlet end of the micro-infusion pump 12. The outlet end of the micro-infusion pump 12 is detachably connected to one end of the drug delivery tube 30. The other end of the drug delivery tube 30 is fixedly connected to the drug release plug 3. The drug delivery tube 30 is reserved on the dressing change pad. On the other side of the substrate 13, a control panel 17 is integrated. The control panel 17 is used to control the operation of the micro-infusion pump 12. When in use, the control panel 17 can preset parameters according to the needs of the patient's condition, so as to control the infusion time, frequency and start and stop of the micro-infusion pump 12 in a timely and quantitative manner, so as to transfer the medicine in the infusion bag 14 to the drug release plug 3 through the drug infusion tube 30.

[0050] Since the outlet of the micro-infusion pump 12 is detached from the infusion tube 30, the dressing pad can be replaced. After use, the outlet of the micro-infusion pump 12 is separated from the infusion tube 30, and the infusion tube 30 of the new dressing pad is connected to the outlet of the micro-infusion pump 12.

[0051] It should be noted that a battery (not shown in the figure) is also provided in the substrate 13, which is electrically connected to the control panel 17 and the micro-infusion pump 12, to supply power to the control panel 17 and the micro-infusion pump 12. How to achieve the electrical connection between the control panel 17, the micro-infusion pump 12 and the battery is a common and mature technical means in the field, and will not be elaborated on here.

[0052] Furthermore, a cover plate 11 is flipped and installed on one side of the substrate 13. When the cover plate 11 is closed, it can cover the infusion connector 16 and the micro-infusion pump 12 to prevent exposure, contamination or damage to the infusion connector 16 and the micro-infusion pump 12. A buckle is provided on the other side of the flipped connection between the cover plate 11 and the substrate 13 to detachably fix this side to the substrate 13, making it easy to open the cover plate 11.

[0053] The dressing change pad includes an absorbent pad 21 and a sponge cone 23 adhesively attached to the absorbent pad 21. The outer surface of the absorbent pad 21 has an adhesive layer to adhere it to the patient's anal, perineal, and buttock skin. The absorbent pad 21 is used to absorb stains or spilled medication to ensure that the perineal and buttock areas are dry and clean. The shape of the sponge cone 23 conforms to the shape of the anal and perineal groove, with complementary concave and convex features, allowing it to fit closely to the anal and perineal area.

[0054] Furthermore, a medication application groove 22 can be provided at the top of the sponge cone 23. The medication application groove 22 can hold different topical ointments or creams as needed. This design ensures that the medication is always in close contact with the anus and continuously acts on the lesion or wound to maximize its efficacy and achieve a combined internal and external treatment effect. At the same time, it enables the topical medication to work continuously on the anal lesion or wound around the clock.

[0055] Furthermore, multiple water guide holes 24 are provided on the side of the sponge cone 23, see [reference]. Figure 2 This allows the fluid overflowing from the anus to be directed to the bottom absorbent pad 21, further ensuring the cleanliness of the patient's anus and perineum and improving comfort.

[0056] In this article, the terms "upper end," "surface," "lower end," and "surface" refer to, as follows: Figure 7 The positional relationship of the sponge cone 23 shown is not intended to imply that it must face a fixed direction during actual installation. It is merely to illustrate the positional or connection relationships between the components. Terms such as "upper" and "lower" do not constitute absolute spatial limitations, but rather concepts of relative position. This is understandable to those skilled in the art.

[0057] The suppository 3 is made of polymer or soft material, with a smooth bullet-shaped, conical, spherical, or ellipsoidal front end. Its diameter can be selected from 8mm, 10mm, 12mm, etc. The suppository 3 includes a suppository body 31, which has an inner chamber 32. The inner chamber 32 of the suppository body 31 is filled with a water-absorbing and water-retaining material, such as a sponge or other liquid-absorbing material. The surface of the suppository body 31 has a plurality of micropores 33 that communicate with the inner chamber 32. The diameter of the micropores 33 is 0.2mm-0.6mm. The tail of the suppository 3 is connected to the infusion tube 30. When the suppository 3 is inserted into the patient's anus, the liquid medicine discharged from the infusion device enters the suppository 3 through the infusion tube 30. The water-absorbing and water-retaining material can absorb the liquid medicine and temporarily retain it. Then, under the action of water pressure, it is slowly released through the micropores 33 to achieve the purpose of slow and continuous drug administration to the patient's anus and rectum.

[0058] A temperature sensor 37 or a drug concentration sensor 34 is installed inside the drug-releasing suppository 3 to monitor the patient's body temperature or the concentration of the drug solution inside the suppository 3 in real time. The sensor transmits signals and controls the suppository via a data cable to the smart chip and circuit board in the control panel 17. When the patient's body temperature or the concentration of the drug solution inside the suppository 3 changes, the temperature sensor 37 or the drug concentration sensor 34 sends a signal to the smart chip and circuit board in the control panel 17. The smart chip then automatically controls the infusion time, cycle, and frequency of the micro-infusion pump 12 to achieve intelligent drug delivery. If necessary, both the temperature sensor 37 and the drug concentration sensor 34 can be installed simultaneously inside the suppository 3.

[0059] Temperature sensor 37 can be model TMP117MAIDRVR; drug concentration sensor 34 can be model 34TMP117MAIDRVR.

[0060] This embodiment achieves continuous, slow, precise, and intelligent drug delivery within the rectum through the aforementioned structure and function. Combined with the continuous application of medication through the external sponge cone and its drug delivery groove, it greatly improves the duration and efficiency of drug action. Furthermore, the daily operation time for patients does not exceed 3 minutes, eliminating the need for daily trips to the hospital, significantly reducing pain and psychological burden, and improving treatment compliance and recovery speed.

[0061] Example 2

[0062] This embodiment is a further optimization based on Embodiment 1. The parts that are the same as those described above will not be repeated here. Figures 1 to 7 As shown, in order to better realize the present invention, the following configuration is adopted: In this embodiment, the drug release suppository 3 can be retracted into the sponge cone 23 to clean the stains on the surface of the drug release suppository 3.

[0063] An installation chamber is provided inside the sponge cone 23, and a receiving through hole is provided on the upper side of the installation chamber. The receiving through hole corresponds to the position of the drug release plug 3. The drug release plug 3 can extend or retract into the installation chamber. A rubber thrust member is provided in the installation chamber to push the drug release plug 3 out of the sponge cone 23. A base plate 36 is provided at the upper end of the rubber thrust member, and a soft sleeve 35 connected to the sponge cone 23 is provided on the upper side of the base plate 36. The soft sleeve 35 has a certain vertical support force. The soft sleeve 35 will be compressed and deformed both vertically and radially. At the same time, the upper end of the drug delivery tube 30 is embedded in the soft sleeve 35. The soft sleeve 35, as the part extending out of the sponge cone 23, improves the comfort of the device during use. The upper ends of the two connecting rods located on the upper side are bent to avoid interference with the wall of the receiving through hole.

[0064] The rubber thrust component includes two symmetrically arranged bent rubber springs 41. The lower end of the bent rubber springs 41 is bonded and fixed to the bottom of the mounting chamber, while the upper end is not connected to any component. However, the upper end of the bent rubber springs 41 is located directly below the base plate 36. An inclined rubber spring 42 is fixed to the inner side of the two bent rubber springs 41. The upper end of the inclined rubber spring 42 is connected to the base plate 36, and the elastic coefficient of the bent rubber springs 41 is greater than that of the inclined rubber spring 42. When the base plate 36 moves towards the mounting chamber, the inclined rubber spring 42 is first compressed and bent, thus accumulating force. When the base plate 36 contacts the upper end of the bent rubber spring 41, it will compress and bend the bent rubber spring 41, thus accumulating force and achieving a secondary force that pushes the base plate 36 outward, ensuring sufficient pushing force on the base plate 36.

[0065] It should be noted that the bent rubber block 41 and the inclined rubber block 42 of the rubber thrust component are both made of rubber material with a certain elasticity. They have the property of deformation and can store force after deformation, and this force will be applied to the base plate 36.

[0066] A bottom adhesive cloth 51 is installed on the underside of the absorbent pad 21. One end of the bottom adhesive cloth 51 is sewn to the absorbent pad 21, and the middle part is glued to the absorbent pad 21. The other end of the bottom adhesive cloth 51 has a pull cloth 52 that cannot be glued to the absorbent pad 21, which is used by the patient to pull and tear off the bottom adhesive cloth 51. A pull rope 43 is connected between the bottom adhesive cloth 51 and the bottom of the base plate 36. When the bottom adhesive cloth 51 is torn off, as the bottom adhesive cloth 51 is pulled, under the traction of the pull rope 43, the drug release plug 3 retracts into the installation chamber through the storage through hole, so that the bent rubber spring block 41 and the inclined rubber spring block 42 of the rubber thrust component bend and store force.

[0067] A laterally movable gel wiping block 64 is provided on both sides of the receiving through hole. A telescopic bladder 63 is installed on the side wall of the receiving through hole, and the inner side of the telescopic bladder 63 is fixedly connected to the side wall of the installation chamber. The outer side of the telescopic bladder 63 is fixed to the outer end of the gel wiping block 64. Therefore, when the telescopic bladder 63 expands, it will push the gel wiping block 64 outward as a whole. Conversely, the gel wiping block 64 will be pushed inward. An elastic airbag 61 is provided on the bottom adhesive cloth 51. The elastic airbag 61 is connected to the two telescopic bladders 63 through an air tube 62. When the elastic airbag 61 is squeezed, the air in the elastic airbag 61 enters the two telescopic bladders 63, causing the telescopic bladders 63 to expand and further push the gel wiping block 64 outward. Conversely, when the elastic airbag 61 is released, the elastic airbag 61 will extract the air in the telescopic bladders 63 due to its own expansion elasticity, causing the telescopic bladders 63 to contract and the gel wiping block 64 to move inward.

[0068] Furthermore, the inner ends of the two colloid wiping blocks 64 have a semi-circular cross-section. The inner hole of the semi-circular structure is slightly smaller than the outer diameter of the suppository 3, so that the inner ends of the two colloid wiping blocks 64 can be in close contact with the outer surface of the suppository 3. The inner ends of the colloid wiping blocks 64 are provided with a multi-layered protrusion structure, which can perform multi-layer cleaning on the surface of the suppository 3.

[0069] When removing the device from the patient's anus, first squeeze the elastic airbag 61 to inflate the two telescopic bladders 63 and displace the two gel pads 64 outward, making room for the suppository 3 to retract. Then, tear the bottom adhesive cloth 51 with the pull cloth 52. Under the pull of the pull rope 43, the rubber thrust member deforms and the overall length shortens, and the suppository 3 retracts into the installation chamber. The suppository 3 will not come into contact with the gel pads 64, which can prevent the stains on the suppository 3 from sticking to the gel pads 64. Then, release the squeeze on the elastic airbag 61. The elastic airbag 61 absorbs the air in the telescopic bladder 63, the gel pads 64 displace inward, and the absorbent pad 21 is torn away from the patient's skin, thus achieving removal. When the device is placed at the patient's anus, the bottom adhesive cloth 51 is reattached to the absorbent pad 21. During this process, the rubber thrust member extends in length, and the suppository 3 extends out from the receiving hole. The colloid wiping block 64 wipes the outer surface of the suppository 3 to remove the dirt from the surface of the suppository 3 and leave the dirt inside the sponge cone 23, ensuring that the outer surface of the suppository 3 is basically clean when it is used again. Finally, the suppository 3 can be reinserted into the patient's anus, and the device is fixed to the patient's skin surface by the absorbent pad 21.

[0070] It should be noted that the rubber thrust component in this embodiment is located inside the sponge cone 23. Since the elasticity of the sponge cone 23 itself can play a buffering role, and the rubber thrust component itself is also elastic, it can avoid causing discomfort to the patient during use.

[0071] The above description is merely a preferred embodiment of the present invention and is illustrative rather than restrictive. Those skilled in the art will understand that many changes, modifications, and even equivalents can be made within the spirit and scope defined by the claims of the present invention, all of which will fall within the protection scope of the present invention.

Claims

1. An intelligent anorectal sustained-release drug delivery device, characterized in that, Includes an infusion setter, a dressing change pad, and a release plug (3) connected to the infusion setter via an infusion tube (30); The suppository (3) is placed on the anal side of the dressing pad and inserted into the anus through the infusion tube (30) that passes through the dressing pad; The infusion device delivers the drug solution to the drug release plug (3) in a timed and quantitative manner through the infusion tube (30), and slowly releases it into the anus and rectum through the micropores (33) on the surface of the drug release plug (3), so as to achieve the effect of the drug solution in the anus continuously and around the clock. The dressing change pad includes an absorbent pad (21) and a sponge cone (23) set on the absorbent pad (21). The absorbent pad (21) is used to absorb the liquid leaking from the anus to keep the perineum and buttocks dry and clean. The sponge cone (23) fits the shape of the anus and perineum, with its concave and convex shapes complementing each other. An installation chamber is provided inside the sponge cone (23), and a receiving through hole corresponding to the drug release plug (3) is provided above the installation chamber; a rubber thrust member is provided inside the installation chamber, which is used to push the drug release plug (3) out of the sponge cone (23); a base plate (36) is provided at the upper end of the rubber thrust member, and a soft sleeve (35) connected to the sponge cone (23) is provided on the upper side of the base plate (36). The bottom of the absorbent pad (21) is provided with a bottom adhesive cloth (51). One end of the bottom adhesive cloth (51) is fixedly connected to the absorbent pad (21), and the other areas are bonded to the absorbent pad (21). A pull rope (43) is connected between the bottom adhesive cloth (51) and the bottom plate (36). By tearing off or re-attaching the bottom adhesive cloth (51), the pull rope (43) is driven to extend or shorten the rubber thrust member, thereby causing the drug release plug (3) to extend or retract. The rubber thrust component includes two symmetrically arranged bent rubber blocks (41), and an inclined rubber block (42) is fixed on the inner side of the two bent rubber blocks (41). The upper end of the inclined rubber block (42) is connected to the base plate (36), and the elastic coefficient of the bent rubber block (41) is greater than that of the inclined rubber block (42). The receiving through hole is provided with a colloid wiping block (64) that can be moved laterally and a telescopic bladder (63) that pushes the colloid wiping block (64) outward when it expands. An elastic air bladder (61) is provided on the bottom adhesive cloth (51). The elastic air bladder (61) and the telescopic bladder (63) are connected by an air tube (62).

2. The intelligent anorectal sustained-release drug delivery device according to claim 1, characterized in that, The infusion device includes a base plate (13), on which an infusion bag (14) is detachably mounted and a micro-infusion pump (12) is provided to pump out the drug solution in the infusion bag (14). The micro-infusion pump (12) is detachably connected to the infusion tube (30). The substrate (13) is also provided with a control panel (17) electrically connected to the micro-infusion pump (12) and a storage battery; The control panel (17) presets parameters according to the patient's condition, thereby controlling the infusion cycle, frequency and start / stop of the micro-infusion pump (12) in a timely and quantitative manner, so as to transfer the drug solution in the infusion bag (14) to the drug release plug (3) through the infusion tube (30).

3. The intelligent anorectal sustained-release drug delivery device according to claim 2, characterized in that, An infusion connector (16) is installed on one side of the substrate (13), and the outlet of the infusion bag (14) is sealed and inserted into the inlet end of the infusion connector (16); the outlet end of the infusion connector (16) is connected to the inlet end of the micro-infusion pump (12).

4. The intelligent anorectal sustained-release drug delivery device according to claim 1, characterized in that, The sponge cone (23) is provided with a drug delivery groove (22) on the side that contacts the anus. The drug delivery groove (22) can release external drugs so that the external drugs can work on the anal lesions or wounds all day long.

5. The intelligent anorectal sustained-release drug delivery device according to claim 1, characterized in that, The drug-releasing suppository (3) is made of polymer or soft material and includes a suppository body (31) and an inner chamber (32) disposed inside the suppository body (31). The micropore (33) is connected to the inner chamber (32) to enable the drug liquid to be released to the outside through the micropore (33).

6. The intelligent anorectal sustained-release drug delivery device according to claim 5, characterized in that, The front end of the plug (31) is rounded, bullet-shaped, conical, spherical or ellipsoidal.

7. The intelligent anorectal sustained-release drug delivery device according to claim 5, characterized in that, The inner chamber (32) of the plug (31) is filled with water-absorbing and water-storing material.

8. The intelligent anorectal sustained-release drug delivery device according to claim 1, characterized in that, The side of the sponge cone (23) is provided with multiple water guide holes (24) to guide the liquid overflowing from the anus to the bottom absorbent pad (21).

9. The intelligent anorectal sustained-release drug delivery device according to claim 2, characterized in that, The drug delivery suppository (3) is equipped with a temperature sensor (37) or a drug concentration sensor (34) to monitor the patient's anal temperature or drug concentration in real time and feed the monitoring data back to the infusion device in real time. Under the intelligent control of the control panel (17) containing a microchip, the infusion time, cycle and frequency can be intelligently adjusted.

10. The intelligent anorectal sustained-release drug delivery device according to claim 1, characterized in that, The inner end of the colloid wiping block (64) has a semi-circular cross-section and the inner end of the colloid wiping block (64) is provided with a multi-layer protrusion structure to achieve multiple close contacts with the outer surface of the drug release suppository (3).

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