Camellia oil composition for relaxing bowel and preparation method thereof

Abstract

The invention discloses a camellia oil composition for relaxing bowel and a preparation method thereof, and belongs to the technical field of compositions. Comprising the following steps: mixing angelica sinensis, bunge cherry seeds, peach kernels, trichosanthes kirilowii kernels, astragalus membranaceus, Laiyang adenophora stricta, immature bitter oranges, mangnolia officinalis, aster, moringa oleifera leaves and raw atractylodes macrocephala koidz, soaking through water, boiling with big fire, continuously decocting with small fire to obtain a concentrated solution, adding camellia oil, and uniformly stirring to obtain the camellia oil composition for relaxing bowel. The intestine moistening and bowel relaxing effects are improved through the synergistic effect of the whole angelica sinensis, the bunge cherry seeds, the peach kernels, the semen trichosanthis, the astragalus membranaceus, the Laiyang adenophora stricta, the immature bitter oranges, the mangnolia officinalis, the aster, the moringa oleifera leaves, the raw atractylodes macrocephala koidz and the camellia oil in the composition.

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of compositions, and particularly relates to a camellia oil intestinal lubricating and defecation composition and a preparation method thereof. BACKGROUND

[0002] Constipation is a common disease in the digestive system, and the main clinical manifestations are low defecation frequency, difficult defecation process, dry or hard stool, etc. Long-term constipation not only can reduce the quality of life of patients, but also can cause other diseases. Therefore, it is extremely important to take reasonable measures for appropriate treatment. At present, there are many Chinese and Western medicines for treating constipation in the clinic. Western medicine usually takes mild and less side effect laxatives to help defecation, but long-term taking can easily cause laxative dependence, weaken the peristalsis of the small intestine, damage the intestinal nervous system, and form a vicious cycle. Chinese medicine usually uses medicinal materials with food origin to form a prescription, which is beneficial to health. For example, the Wuren tea is composed of hemp seeds, jujube seeds, sweet almonds, coix seed, peach kernel, radish seed, momordica grosvenorii and green tea, hemp seeds are the monarch drug, sweet almonds, coix seed, peach kernel, radish seed and momordica grosvenorii are the ministerial drugs, and green tea is added to improve the taste of the medicinal tea, dilute the bitter and astringent taste, and clinically show that the Wuren tea has a certain effect on improving the symptoms of constipation. However, the Wuren tea has the defects of lubrication without movement, short-acting effect and narrow application population, which limits the clinical application. Therefore, it is of important practical significance and market value to develop a safe and effective intestinal lubricating and defecation product with long-acting effect and wide application population. SUMMARY

[0003] The application aims to provide a camellia oil intestinal lubricating and defecation composition and a preparation method thereof, and provide a safe and effective intestinal lubricating and defecation product with long-acting effect and wide application population, and improve the intestinal lubricating and defecation effect.

[0004] The application can be achieved by the following technical scheme. A preparation method of a camellia oil intestinal lubricating and defecation composition, comprising the following steps: The whole angelica, jujube seeds, peach kernel, trichosanthes seed, astragalus, Laiyang radix ginseng, citrus fruit, magnolia officinalis, radix indi, leaf of morinda citrifolia, raw atractylodes rhizome are mixed, and then boiled by 2-3L water, and then boiled by small fire to obtain a concentrated solution with a volume of 80-120mL, and then the camellia oil is added and stirred to obtain the camellia oil intestinal lubricating and defecation composition.

[0005] As a preferred technical scheme of the application, the mass ratio of the whole angelica, jujube seeds, peach kernel, trichosanthes seed, astragalus, Laiyang radix ginseng, citrus fruit, magnolia officinalis, radix indi, leaf of morinda citrifolia, raw atractylodes rhizome and camellia oil is 10-15:10-15:10-15:10-15:4-8:3-5:4-6:3-5:5-7:7-12:38-48:2-12.

[0006] As a preferred embodiment of the present invention, the mass ratio of Angelica sinensis, Prunus japonica, Prunus persica, Trichosanthes kirilowii, Astragalus membranaceus, Adenophora stricta, Citrus aurantium, Magnolia officinalis, Aster tataricus, Moringa oleifera, Atractylodes macrocephala, and Camellia oleifera oil is 12:12:12:12:6:4:5:4:6:9:43:7.

[0007] As a preferred embodiment of the present invention, the method for preparing camellia oil includes the following steps: Camellia oleifera fruit is steamed and cracked to obtain camellia oleifera seeds. The camellia oleifera seeds are crushed and then baked in a forced-air oven at 125-145℃ for 2-4 hours. Distilled water is then evenly sprayed onto the surface of the dried and crushed camellia oleifera seeds to reabsorb water until the water content of the camellia oleifera seeds accounts for 5-8% of the total mass of the rehydrated camellia oleifera seeds. The seeds are then pressed to obtain camellia oil.

[0008] A camellia oil laxative composition prepared by the above-described preparation method.

[0009] The beneficial effects of this invention are: This invention utilizes the synergistic effect of Angelica sinensis, Prunus japonica seed, Prunus persica seed, Trichosanthes kirilowii seed, Astragalus membranaceus, Adenophora stricta, Citrus aurantium, Magnolia officinalis, Aster tataricus, Moringa oleifera leaf, Atractylodes macrocephala, and Camellia japonica oil to achieve a laxative effect. The specific mechanism is as follows: Astragalus membranaceus tonifies qi and raises yang, while Atractylodes macrocephala invigorates the spleen and benefits qi. The active ingredients in both (such as astragalus polysaccharides and atractylodes macrocephala lactones) can promote calcium metabolism in intestinal smooth muscle cells. 2+ Internal flow provides the driving force for intestinal peristalsis; Fructus Aurantii Immaturus and Cortex Magnoliae Officinalis are a classic pair of qi-regulating herbs that can break up qi stagnation and relieve bloating, regulate the rhythmic peristalsis of the intestines, and the two work together to relax intestinal smooth muscle spasms, while promoting propulsive contractions and clearing the pathways blocked by qi stagnation; the active ingredients of Aster tataricus (such as isochlorogenic acid) can bind to intestinal M2 / M3 receptors, further regulating the contraction signals of intestinal smooth muscle and enhancing peristaltic power; Astragalus membranaceus, Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, and Aster tataricus work together to solve the problem of insufficient power caused by qi deficiency and poor conduction caused by qi stagnation, thereby improving the active peristalsis ability of the intestines from the root. Angelica sinensis nourishes blood and moistens the intestines, while Adenophora stricta nourishes yin and generates fluids. By regulating the expression of intestinal aquaporins, both replenish endogenous intestinal fluids, fundamentally improving intestinal dryness. The oil components of Prunus japonica and other nuts, along with the lubricating carrier of camellia oil, can directly soften stool. At the same time, camellia oil can dissolve the fat-soluble active components (such as volatile oils and unsaturated fatty acids) in Angelica sinensis and peach kernels, enhancing the bioavailability of these components and strengthening the moisturizing effect. The synergistic effect of internal and external treatments not only solves the surface problem of dry stools but also improves the deeper state of intestinal fluid deficiency. Radix Astragali and Angelica sinensis can synergistically promote the proliferation of colonic mucosal epithelial cells, repair mucosal integrity, improve colonic mucosal blood circulation, and reduce inflammatory pathological damage; polysaccharides and flavonoids in Moringa oleifera leaves can promote the secretion of mucin by intestinal mucous cells, repair the mucus barrier, and reduce the risk of recurrence of intestinal damage and constipation after recovery; Isorosmarin in Eclipta prostrata, volatile oil in Angelica sinensis, and flavonoids in Semen Persicae can synergistically act on intestinal M2 / M3 receptors, regulate Ca 2+ channel opening, promote Ca 2+ influx; Ca 2+ influx further activates PKC protein, and finally regulates intestinal smooth muscle contraction, mucus secretion, and water transport, forming a multi-component and multi-target signal network to amplify the effect of moistening the intestines.

[0010] Through the synergistic effect of the components, the core problems of constipation such as insufficient power, deficiency of body fluid, stagnation of qi, and damage to the mucosa can be solved at the same time, avoiding the limitations of single moistening drugs that only soften the stool without promoting, or single qi-tonifying drugs that only promote without moistening the stool; by tonifying qi, nourishing yin, repairing the mucosa, improving intestinal motility and body fluid environment, the recurrence rate of constipation is reduced; there is no strong purgative component, relying on the mild mechanism of tonifying qi and moistening dryness, which will not cause diarrhea, abdominal pain or drug dependence; camellia oil as a carrier enhances the efficacy utilization rate and enhances the synergistic effect of the components. DETAILED DESCRIPTION

[0011] To further illustrate the technical means and effects adopted by the present application to achieve the predetermined invention purpose, the specific embodiments, structures, features and effects according to the present application are described in detail as follows in combination with examples.

[0012] Example 1 A preparation method of a camellia oil intestinal moistening and defecation composition, comprising the following steps: Take Angelica sinensis, Prunus armeniaca, Semen Persicae, Trichosanthes kirilowii, Radix Astragali, Leyang Adenophora, Citrus aurantium, Magnolia officinalis, Eclipta prostrata, Moringa oleifera leaves, and raw Atractylodes lancea, mix them, and then soak them in 2L water until they are fully soaked, then boil them with a large fire, and continue to decoct them with a small fire to obtain a concentrated solution with a volume of 80mL, then add camellia oil and stir until uniform, and the camellia oil intestinal moistening and defecation composition is obtained.

[0013] The mass ratio of Angelica sinensis, Prunus armeniaca, Semen Persicae, Trichosanthes kirilowii, Radix Astragali, Leyang Adenophora, Citrus aurantium, Magnolia officinalis, Eclipta prostrata, Moringa oleifera leaves, raw Atractylodes lancea, and camellia oil is 10:10:10:10:4:3:4:3:5:7:38:2.

[0014] The preparation method of the camellia oil comprises the following steps: Take the oil tea fruit after steam explosion de-pulp, get oil tea seed; take the oil tea seed broken processing, then at 125 ℃ under the blast drying 4h, distill water is evenly sprayed to the dry broken oil tea seed surface, re-absorb moisture to the oil tea seed moisture quality accounts for 5% of the total mass of the re-hydrated oil tea seed, squeeze, namely the camellia oil.

[0015] Example 2 A preparation method of a camellia oil intestinal lubrication and defecation composition, comprising the following steps: Take the whole angelica, juglans regia, persica, trichosanthes, astragalus, layang sand, citrus aurantium, magnolia officinalis, viola, moringa leaf, raw atractylodes mixed, after 2.5L water soak through, boiling water, continue to decoct, get the volume of 100ml of concentrated solution, add camellia oil stirring, namely the camellia oil intestinal lubrication and defecation composition.

[0016] The mass ratio of the whole angelica, juglans regia, persica, trichosanthes, astragalus, layang sand, citrus aurantium, magnolia officinalis, viola, moringa leaf, raw atractylodes and camellia oil is 12:12:12:12:6:4:5:4:6:9:43:7.

[0017] The preparation method of the camellia oil comprises the following steps: Take the oil tea fruit after steam explosion de-pulp, get oil tea seed; take the oil tea seed broken processing, then at 125 ℃ under the blast drying 4h, distill water is evenly sprayed to the dry broken oil tea seed surface, re-absorb moisture to the oil tea seed moisture quality accounts for 5% of the total mass of the re-hydrated oil tea seed, squeeze, namely the camellia oil.

[0018] Example 3 A preparation method of a camellia oil intestinal lubrication and defecation composition, comprising the following steps: Take the whole angelica, juglans regia, persica, trichosanthes, astragalus, layang sand, citrus aurantium, magnolia officinalis, viola, moringa leaf, raw atractylodes mixed, after 2.5L water soak through, boiling water, continue to decoct, get the volume of 100ml of concentrated solution, add camellia oil stirring, namely the camellia oil intestinal lubrication and defecation composition.

[0019] The mass ratio of the whole angelica, juglans regia, persica, trichosanthes, astragalus, layang sand, citrus aurantium, magnolia officinalis, viola, moringa leaf, raw atractylodes and camellia oil is 12:12:12:12:6:4:5:4:6:9:43:7.

[0020] The preparation method of the camellia oil comprises the following steps: Camellia oleifera fruit is steamed and de-burred to obtain camellia oleifera seeds. The camellia oleifera seeds are crushed and then baked at 145℃ for 2 hours. Distilled water is evenly sprayed onto the surface of the dried crushed camellia oleifera seeds to reabsorb water until the water content of the camellia oleifera seeds accounts for 8% of the total mass of the rehydrated camellia oleifera seeds. The seeds are then pressed to obtain camellia oil.

[0021] Comparative Example 1 This comparative example provides a camellia oil laxative composition. The only difference between this composition and Example 2 is that it does not contain whole Angelica sinensis. The reduced amount is distributed in proportion to whole Prunus japonica kernel, peach kernel, Trichosanthes kirilowii kernel, Astragalus membranaceus, Adenophora stricta, Citrus aurantium, Magnolia officinalis, Aster tataricus, Moringa oleifera leaf, raw Atractylodes macrocephala and camellia oil. The remaining components and their amounts remain unchanged.

[0022] Comparative Example 2 This comparative example provides a camellia oil laxative composition. The only difference between this composition and Example 2 is that it does not contain Prunus japonica seed. The reduced amount is distributed in proportion to Angelica sinensis, Prunus persica seed, Trichosanthes kirilowii seed, Astragalus membranaceus, Adenophora stricta, Citrus aurantium, Magnolia officinalis, Aster tataricus, Moringa oleifera leaf, Atractylodes macrocephala, and camellia oil. The remaining components and their amounts remain unchanged.

[0023] Comparative Example 3 This comparative example provides a camellia oil laxative composition. The only difference between this composition and Example 2 is that it does not contain peach kernels. The reduced amount is distributed in proportion to Angelica sinensis, Prunus japonica, Trichosanthes kirilowii, Astragalus membranaceus, Adenophora stricta, Citrus aurantium, Magnolia officinalis, Aster tataricus, Moringa oleifera, Atractylodes macrocephala, and camellia oil. The remaining components and their amounts remain unchanged.

[0024] Comparative Example 4 This comparative example provides a camellia oil laxative composition. The only difference between this composition and Example 2 is that it does not contain Trichosanthes kirilowii seed. The reduced amount is distributed in proportion to Angelica sinensis, Prunus japonica seed, Prunus persica seed, Astragalus membranaceus, Adenophora stricta, Citrus aurantium, Magnolia officinalis, Aster tataricus, Moringa oleifera leaf, Atractylodes macrocephala, and camellia oil. The remaining components and their amounts remain unchanged.

[0025] Comparative Example 5 This comparative example provides a camellia oil laxative composition. The only difference between this composition and Example 2 is that it does not contain Astragalus membranaceus. The reduced amount is distributed in proportion to Angelica sinensis, Prunus japonica, Prunus persica, Trichosanthes kirilowii, Adenophora stricta, Citrus aurantium, Magnolia officinalis, Aster tataricus, Moringa oleifera, Atractylodes macrocephala, and camellia oil. The remaining components and their amounts remain unchanged.

[0026] Comparative Example 6 This comparative example provides a camellia oil laxative composition. The only difference between this composition and Example 2 is that it does not contain Laiyang sand ginseng. The reduced amount is distributed in proportion to whole angelica, apricot kernel, peach kernel, trichosanthes kernel, astragalus, immature bitter orange, magnolia bark, aster, moringa leaf, raw atractylodes macrocephala and camellia oil. The remaining components and their amounts remain unchanged.

[0027] Comparative Example 7 This comparative example provides a camellia oil laxative composition. The only difference between this composition and Example 2 is that it does not contain immature bitter orange. The reduced amount of immature bitter orange is distributed in proportion to Angelica sinensis, Prunus japonica, Prunus persica, Trichosanthes kirilowii, Astragalus membranaceus, Adenophora stricta, Magnolia officinalis, Aster tataricus, Moringa oleifera, Atractylodes macrocephala, and camellia oil. The remaining components and their amounts remain unchanged.

[0028] Comparative Example 8 This comparative example provides a camellia oil laxative composition. The only difference between this composition and Example 2 is that it does not contain Magnolia officinalis. The reduced amount is distributed in proportion to Angelica sinensis, Prunus japonica, Prunus persica, Trichosanthes kirilowii, Astragalus membranaceus, Adenophora stricta, Citrus aurantium, Aster tataricus, Moringa oleifera, Atractylodes macrocephala, and camellia oil. The remaining components and their amounts remain unchanged.

[0029] Comparative Example 9 This comparative example provides a camellia oil laxative composition. The only difference between this composition and Example 2 is that it does not contain aster. The reduced amount of aster is distributed in proportion to Angelica sinensis, Prunus japonica, Prunus persica, Trichosanthes kirilowii, Astragalus membranaceus, Adenophora stricta, Citrus aurantium, Magnolia officinalis, Moringa oleifera, Atractylodes macrocephala, and camellia oil. The remaining components and their amounts remain unchanged.

[0030] Comparative Example 10 This comparative example provides a camellia oil laxative composition. The only difference between this composition and Example 2 is that it does not contain moringa leaves. The reduced amount is distributed in proportion to Angelica sinensis, Prunus japonica, Prunus persica, Trichosanthes kirilowii, Astragalus membranaceus, Adenophora stricta, Citrus aurantium, Magnolia officinalis, Aster tataricus, Atractylodes macrocephala, and camellia oil. The remaining components and their amounts remain unchanged.

[0031] Comparative Example 11 This comparative example provides a camellia oil laxative composition. The only difference between this composition and Example 2 is that it does not contain raw Atractylodes macrocephala. The reduced amount is distributed in proportion to Angelica sinensis, Prunus japonica, Prunus persica, Trichosanthes kirilowii, Astragalus membranaceus, Adenophora stricta, Citrus aurantium, Magnolia officinalis, Aster tataricus, Moringa oleifera leaves and camellia oil. The remaining components and their amounts remain unchanged.

[0032] Comparative Example 12 This comparative example provides a camellia oil-based laxative composition. The only difference between this composition and Example 2 is that it does not contain camellia oil. The reduced amount is allocated to Angelica sinensis, Prunus japonica, Prunus persica, Trichosanthes kirilowii, Astragalus membranaceus, Adenophora stricta, Citrus aurantium, Magnolia officinalis, Aster tataricus, Moringa oleifera, and Atractylodes macrocephala in proportion to the ingredients. The remaining components and their amounts remain unchanged.

[0033] Experimental process and results of the test on the laxative effect I. Experimental Procedure 1. Experimental Materials Experimental animals: 170 two-month-old SPF-grade C57BL / 6J mice, half male and half female, weighing 25±2g. Housing environment: 12-hour day / night cycle, room temperature 24±2℃, free access to food and water, acclimatization for one week.

[0034] Experimental drugs: Camellia oil laxative compositions prepared in Examples 1-3 and Comparative Examples 1-12; loperamide hydrochloride (2 mg / capsule); Indian ink (analytical grade); purified water.

[0035] 2. Experimental Grouping 170 mice were randomly divided into 17 groups of 10 mice each. The specific groupings are as follows: Blank control group: no drug was administered, only an equal amount of purified water was given; Model control group: after modeling, an equal amount of purified water was given; Experimental group: Example 1 group, Example 2 group, Example 3 group; Comparative group: Comparative group 1-12.

[0036] 3. Preparation of a constipation model Except for the blank control group, the other 16 groups used loperamide hydrochloride to establish a constipation model: loperamide hydrochloride was dissolved in 1 mL of purified water and administered by gavage at a dose of 70 mg / kg twice a day at 7:00 AM and 7:00 PM for 7 consecutive days; the blank control group was administered the same amount of purified water by gavage during the same period. During the modeling period, the activity status, fur condition, feeding status and survival status of the mice were observed daily.

[0037] 4. Drug intervention After confirming successful modeling on day 7, drug intervention was initiated on day 8 and continued for 7 days: Examples 1-3 and Comparative Examples 1-12: The corresponding camellia oil laxative composition was administered by gavage at a dose of 0.2 mL / 25 g body weight once daily; Blank control group and model control group: The same amount of purified water was administered by gavage once daily.

[0038] 5. Indicator Testing (1) General observation Daily records were kept of the mice's weight, activity level, fur luster, food intake, and survival status.

[0039] (2) Detection of fecal related indicators During the administration period, feces of mice in each group were collected every 24 hours, and the total weight of feces was weighed (accurate to 0.01g). The fecal characteristics were evaluated according to the 4-point scoring method: 4 points (formed soft stool, moist and shiny), 3 points (formed soft stool, slightly dry), 2 points (dry hard stool, granular), and 1 point (hard ball-shaped stool, rough surface).

[0040] (3) Detection of fecal incubation period On the 7th day after administration, mice in each group were fasted for 12 hours and then given a single gavage of the corresponding composition (the blank group and the model group were given purified water). The time from gavage to the first defecation (defecation latency period) was recorded.

[0041] (4) Intestinal propulsion rate detection On the 7th day after drug administration, mice in each group were fasted for 12 hours and then gavaged with the corresponding composition (the blank group and the model group were gavaged with purified water). 30 minutes later, each mouse was gavaged with 0.2 mL of Indian ink. 20 minutes later, the mice were deeply anesthetized with isoflurane, the abdominal cavity was quickly opened, the entire intestine (from the pylorus to the anus) was taken, and after being straightened without tension, the total length of the intestine (L1) and the length of ink travel (L2) were measured. The intestinal propulsion rate was calculated as: D = L2 / L1 × 100%.

[0042] II. Experimental Results 1. General situation Blank control group: Mice were active, had smooth and shiny fur, ate normally, and did not die; Model control group: Mice showed significantly reduced activity, dull and messy fur, reduced food intake, and no deaths; Examples 1-3: The mice showed better activity levels, fur condition, and food intake than the model control group, with no deaths; Comparative Examples 1-12: The mice in these groups were generally in worse condition than those in the Example Group.

[0043] 2. Fecal indicators and defecation latency results are shown in Table 1 below.

[0044] Table 1 3. The intestinal propulsion rate results are shown in Table 2 below.

[0045] Table 2 4. Results Analysis Compared with the blank control group, the model control group showed a significant reduction in fecal weight, a decrease in fecal characteristics score, a prolonged defecation latency period, and a significant decrease in intestinal propulsion rate, indicating that the constipation model was successfully established. In Examples 1-3, all indicators were significantly better than those in the model control group, with Example 2 showing the best effect, indicating that the camellia oil laxative composition can effectively improve constipation symptoms. In Comparative Examples 1-12, all indicators were worse than those in Example 2, indicating that Angelica sinensis, Prunus japonica, Prunus persica, Trichosanthes kirilowii, Astragalus membranaceus, Adenophora stricta, Citrus aurantium, Magnolia officinalis, Aster tataricus, Moringa oleifera, Atractylodes macrocephala, and camellia oil work synergistically in the composition, and none of them can be omitted, which is crucial for the laxative effect.

[0046] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any way. Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art can make some modifications or alterations to the above-disclosed technical content to create equivalent embodiments without departing from the scope of the present invention. Any simple modifications, equivalent changes and alterations made to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention shall still fall within the scope of the present invention.

Claims

1. A process for the preparation of a Camellia oil laxative composition, characterized in that, The preparation method comprises the following steps: The full radix angelicae sinensis, semen pruni, semen persicae, semen trichosanthis, radix astragali, radix ginseng, semen pruni, semen pruni, semen persicae, semen trichosanthis, radix astragali, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, radix ginseng, 2. A process for the preparation of a Camellia oil laxative composition according to claim 1, characterized in that, ​ 3. A process for the preparation of a Camellia oil laxative composition as claimed in claim 2, wherein, ​ 4. A process for the preparation of a Camellia oil laxative composition as claimed in claim 1, wherein, ​ ​ ​

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