Lung-ventilating and cough-relieving liquid traditional Chinese medicine for treating cough and preparation method thereof

Abstract

The invention relates to the technical field of health-care products, and provides a lung-ventilating and cough-relieving liquid traditional Chinese medicine for treating cough and a preparation method thereof.The lung-ventilating and cough-relieving liquid traditional Chinese medicine is prepared from, by weight, 80-90 parts of traditional Chinese medicine extracting solution, 0.4-0.8 part of compound stabilizer and 40-50 parts of deionized water. The lung-ventilating and cough-relieving liquid traditional Chinese medicine provided by the invention has good stability, further has the effects of efficiently dispelling wind, ventilating lung, relieving cough and reducing sputum, and has a good curative effect on diseases such as cough and pulmonary tuberculosis.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of traditional Chinese medicine preparation, in particular to a traditional Chinese medicine for treating cough and a preparation method thereof. BACKGROUND

[0002] In modern society, there are many factors such as heavy work pressure, heavy course load, seasonal changes, poor air quality, cold, viral infection, and many allergens, which lead to the serious and universal problem of cough. Cough is a protective respiratory reflex action of the human body to clear secretions or foreign bodies in the respiratory tract. It is because the mucosa of the throat or trachea is stimulated to rapidly inhale and then strongly exhale, and the vocal cords vibrate to make a sound. However, long-term cough can cause diseases such as upper respiratory tract infection, bronchitis, pneumonia, and acute laryngitis. Moreover, severe cough can cause respiratory tract bleeding, and long-term and frequent severe cough can affect work and rest, and even cause throat pain, hoarseness, and respiratory muscle pain.

[0003] Currently, the main treatment for cough is western medicine, but it has defects such as treating the symptoms but not the root cause and large side effects. Therefore, many research focuses have shifted to Chinese herbal medicine. Traditional Chinese medicine has a history of thousands of years in treating cough. The core treatment method is to ventilate the lungs and stop coughing. Its theoretical basis is derived from the theory of "the lung governing dispersion and descent" in Huangdi Neijing. Classical prescriptions such as San'ao Decoction (ephedra, apricot kernel, and licorice) and Zhisou Powder (platycodon, schizonepeta, and asiatic plantain) have a definite effect on wind-cold binding the lung type of cough by dispersing wind and ventilating the lungs and eliminating phlegm and stopping coughing. However, many traditional Chinese medicines contain flavonoids and volatile oil substances, which have the problems of easy oxidation and poor stability. If not protected, the cough-relieving effect of traditional Chinese medicines will be greatly reduced.

[0004] Patent CN 101181517B discloses a traditional Chinese medicine granule for moistening the lungs and stopping coughing. The traditional Chinese medicine granule is prepared by using common prescription processes and using as main raw materials jixiang grass, rhizoma polygonati, radix pseudostellariae, platycodon, saxifraga, loquat leaf, ephedra, white mulberry bark, poppy husk, north adenosma, licorice, radix rubi, fistularis, hawthorn, areca nut, citron, raphanus, semen lachni, forsythia, periostracum cygni, and has the effects of tonifying qi and nourishing yin, moistening the lungs and stopping coughing. However, the traditional Chinese medicine contains flavonoids such as tiger ear grass, licorice, and platycodon, and unsaturated bond components such as loquat leaf, which have the risk of easy oxidation. The application does not involve protection measures for some easily oxidized traditional Chinese medicine ingredients, which may cause the efficacy of the cough-relieving traditional Chinese medicine granule to disappear or decrease.

[0005] Therefore, there is an urgent need in the market for a traditional Chinese medicine for treating cough with good stability and high efficiency in dispersing wind, ventilating the lungs, stopping coughing, and eliminating phlegm, which has good effects on cough and pulmonary tuberculosis. SUMMARY

[0006] In order to solve the problems in the prior art, the application discloses a traditional Chinese medicine for treating cough, which is obtained by using a plurality of traditional Chinese medicinal materials in combination with an extraction process, and a composite stabilizer is added to make the traditional Chinese medicine for treating cough have good stability and high efficiency in dispersing wind and relieving lung and relieving cough and reducing phlegm, and has good curative effect on cough, pulmonary tuberculosis and other diseases.

[0007] In order to achieve the above-mentioned purpose, the technical scheme adopted by the application is as follows: The application provides a traditional Chinese medicine for treating cough, which comprises the following raw materials in parts by weight: traditional Chinese medicine extract 80-90 parts, composite stabilizer 0.4-0.8 parts, and deionized water 40-50 parts. The traditional Chinese medicine extract comprises the following components in parts by weight: component A 18-31 parts, component B 16-77 parts, and component C 93-166 parts.

[0008] In some embodiments of the application, the component A comprises the following raw materials in parts by weight: Ephedra 4-6 parts, Asarum 3-5 parts, Cinnamomum 8-12 parts, and dried ginger 3-8 parts.

[0009] In some embodiments of the application, the component B comprises the following raw materials in parts by weight: ants 8-12 parts, Earthworm 10-15 parts, honeysuckle 10-20 parts, Prunella vulgaris 8-15 parts, and Malus prunifolia 10-15 parts.

[0010] In some embodiments of the application, the component C comprises the following raw materials in parts by weight: Radix Paeoniae Alba 10-20 parts, Glycyrrhiza 6-12 parts, Platycladus 8-10 parts, Scutellaria 8-15 parts, Cynanchum 10-15 parts, Artemisia 8-20 parts, Crataegus 5-12 parts, Morus 8-12 parts, Houttuynia cordata 10-20 parts, Schisandra 10-15 parts, and Fagara 10-15 parts.

[0011] In some embodiments of the application, the preparation method of the traditional Chinese medicine extract comprises the following steps: (1) After the component A is crushed, deionized water is added for soaking, a volatile oil extractor is connected, and micro-boiling extraction is performed for 3-4 hours, and then the volatile oil is collected, β-cyclodextrin is added, heating and stirring are performed, and freeze-drying is performed to obtain an inclusion compound for standby use; (2) Ethanol aqueous solution is added to the component B, and reflux extraction is performed for 2-3 times at 60-70 DEG C, the filtrate is combined, and ethanol is recovered under reduced pressure to obtain a thick paste for standby use; (3) Deionized water is added to the component C for soaking, and decoction is performed for 2-3 times, the decoction liquid is combined, concentrated, ethanol aqueous solution is added, and standing is performed at 2-5 DEG C, and then filtration is performed to obtain a clear liquid for standby use. (4) mixing the inclusion compound of step (1), the thick paste of step (2) and the clarified liquid of step (3), stirring, to obtain the traditional Chinese medicine extract.

[0012] In step (1), the mass ratio of component A and deionized water is 1: (9-11); the mass ratio of volatile oil and β-cyclodextrin is 1: (5-7); The mass ratio of component B and the aqueous ethanol solution is 1: (9-11); In step (3), the mass ratio of component C and deionized water is 1: (9-11).

[0013] In some embodiments of the present application, the preparation method of the composite stabilizer comprises the following steps: Mixing the loaded curcumin and the acetic acid-sodium acetate buffer solution, stirring, to obtain liquid 1 for standby, mixing the mixture of vitamin C palmitate, anhydrous ethanol and glycerol, stirring, to obtain liquid 2 for standby, mixing liquid 1 and liquid 2, adding Tween 80, stirring, to obtain the composite stabilizer; The addition amount of Tween 80 is 0.3%-1% of the total mass of liquid 1 and liquid 2.

[0014] In some embodiments of the present application, the mass ratio of the loaded curcumin and vitamin C palmitate is 1: (3-6).

[0015] In some embodiments of the present application, the preparation method of the loaded curcumin comprises the following steps: Adding glycyrrhizic acid to deionized water, stirring, to obtain a solution for standby, adding curcumin to the mixed solution, stirring, adding the solution, stirring, high-pressure homogenization, reduced pressure distillation, to obtain the loaded curcumin; The mixed solution is a mixture of ethanol, glycerol and deionized water.

[0016] In some embodiments of the present application, the mass ratio of glycyrrhizic acid and curcumin is 1: (0.5-1).

[0017] Preferably, the mass ratio of glycyrrhizic acid and curcumin is 1:0.9.

[0018] The active ingredients of some traditional Chinese medicine ingredients in the lung-activating and cough-relieving liquid, such as volatile oils, flavonoids and animal proteins, have the problem of poor antioxidant performance. Curcumin, as a natural traditional Chinese medicine ingredient, has good antioxidant effect, but if it is directly added to the cough-relieving liquid, it will precipitate due to poor water solubility, and curcumin itself also has the problem of chemical instability. Directly applying it to the lung-activating and cough-relieving liquid will have the limitations of poor antioxidant effect and low utilization rate.

[0019] The application selects natural and environment-friendly glycyrrhizic acid as a carrier, controls the ratio between curcumin and glycyrrhizic acid, and synthesizes a loaded curcumin, the glycyrrhizic acid has hydrophilic sugar chains and hydrophobic aglycone skeleton structures, the amphiphilic characteristics can spontaneously form micelles in an aqueous solution to realize solubilization and stability improvement of curcumin, and the glycyrrhizic acid also has the effect of promoting drug absorption, and when added in the lung-activating and cough-relieving liquid, can improve the utilization effect of traditional Chinese medicine ingredients, in addition, the loaded curcumin can be well dispersed in the lung-activating and cough-relieving liquid, and the reason is that the intermolecular hydrogen bond and charge repulsion of the loaded curcumin enhance the steric hindrance effect, and then inhibit the particle aggregation and sedimentation.

[0020] Further, the application controls the ratio of the loaded curcumin and vitamin C palmitate as main components to obtain a composite stabilizer, the two form a multi-phase antioxidant network through the hydrophobic embedding and electrostatic adsorption force, play a synergistic antioxidant effect, and then improve the cough-relieving effect of the lung-activating and cough-relieving liquid.

[0021] The application also provides a preparation method of the lung-activating and cough-relieving liquid traditional Chinese medicine for treating cough. The traditional Chinese medicine extract, the composite stabilizer and deionized water are mixed, stirred, filtered, and the lung-activating and cough-relieving liquid traditional Chinese medicine for treating cough is obtained.

[0022] Compared with the prior art, the application has the following beneficial effects: (1) The application discloses a lung-activating and cough-relieving liquid traditional Chinese medicine for treating cough, a traditional Chinese medicine extract is obtained through a plurality of traditional Chinese medicinal materials and an extraction process, and a composite stabilizer is designed to be added, so that the lung-activating and cough-relieving liquid traditional Chinese medicine has good stability through the synergistic effect of components, and has efficient wind-dispersing and lung-activating, cough-relieving and phlegm-resolving effects, and has good effects on cough, pulmonary tuberculosis and other diseases.

[0023] (2) The application designs to use natural and environment-friendly glycyrrhizic acid as a carrier, controls the ratio between curcumin and glycyrrhizic acid, and synthesizes a loaded curcumin, improves the water solubility and stability of curcumin, and can be well dispersed in the lung-activating and cough-relieving liquid, and provides good antioxidant effect; further, the application controls the ratio of the loaded curcumin and vitamin C palmitate as main components to obtain a composite stabilizer, has a synergistic antioxidant effect, and improves the stability of the lung-activating and cough-relieving liquid as a whole, and then improves the cough-relieving effect of the lung-activating and cough-relieving liquid. DETAILED DESCRIPTION

[0024] The application will be described below in combination with specific implementation schemes. It should be noted that the following examples are examples of the application, and are only used to illustrate the application, but not to limit the application. Other combinations and various modifications within the concept of the application can be made without departing from the main idea or scope of the application.

[0025] In the following examples and comparative examples, except for the supported curcumin and the complex stabilizer, all other compound monomers and related reagents used can be purchased from the market.

[0026] Preparation Example 1 The preparation method of traditional Chinese medicine extract includes the following steps: (1) After crushing component A through a 20-mesh sieve, add deionized water (the mass ratio of component A to deionized water is 1:10), soak for 2 hours, connect a volatile oil extractor, extract at 95°C with gentle boiling for 3 hours, collect the volatile oil, add β-cyclodextrin (the mass ratio of volatile oil to β-cyclodextrin is 1:6), stir at 60°C for 2 hours, freeze dry, and obtain the inclusion complex for later use; (2) Add 60wt% ethanol aqueous solution to component B (the mass ratio of component B to ethanol aqueous solution is 1:10), reflux extract twice at 65℃ (1.5h each time), combine the filtrates, and recover ethanol under reduced pressure (-0.08MPa, 50℃) to obtain a thick paste for later use; (3) Add deionized water to component C (the mass ratio of component C to deionized water is 1:10), soak for 30 min, decoct twice (1 h each time), combine the decoctions, concentrate at 60°C to a relative density of 1.10, add 95 wt% ethanol aqueous solution to a 60% alcohol content, let stand at 4°C for 12 h, filter, and obtain a clear liquid for later use. (4) Mix the inclusion complex from step (1), the thick paste from step (2), and the clear liquid from step (3), and stir for 30 minutes to obtain the Chinese herbal extract. By weight, component A includes the following raw materials: 5 parts ephedra, 4 parts asarum, 10 parts cinnamon twig, and 5.5 parts dried ginger; Component B includes the following ingredients: 10 parts ants, 12.5 parts earthworms, 15 parts honeysuckle, 11.5 parts prunella vulgaris, and 12.5 parts spotted sword. Component C includes the following ingredients: 15 parts white peony root, 9 parts licorice root, 9 parts lepidium seed, 11.5 parts scutellaria root, 12.5 parts lycium root bark, 14 parts artemisia annua, 8.5 parts hawthorn, 10 parts mulberry bark, 15 parts houttuynia cordata, 12.5 parts schisandra fruit, and 12.5 parts pinellia tuber. The content of aristolochic acid I in the herbal extract was tested according to the Chinese Pharmacopoeia, and the results met the qualified index (≤0.001mg / kg).

[0027] Preparation Example 2 The method for synthesizing supported curcumin A includes the following steps: Add 2g of glycyrrhizic acid to 20ml of deionized water and stir for 30min to obtain a solution for later use. Add 1.8g of curcumin to 20ml of mixed solution (ethanol:glycerol:deionized water volume ratio of 3:2:5) and stir for 30min. Add the solution at 25℃ (complete within 5min) and stir for 5min. Homogenize under high pressure until the average particle size is 150nm. Distill under reduced pressure (40℃, -0.08MPa) until the ethanol residue is ≤0.5% to obtain supported curcumin A.

[0028] Preparation Example 3 The specific implementation method of the supported curcumin B is the same as that of the supported curcumin A, except that the mass of curcumin is replaced with 0.8g.

[0029] Preparation Example 4 The specific implementation method of the supported curcumin C is the same as that of the supported curcumin A, except that the mass of curcumin is replaced with 2.3g.

[0030] Example 1 A traditional Chinese medicine for treating cough, comprising the following ingredients by weight: 85 parts of herbal extract, 0.6 parts of compound stabilizer, and 45 parts of deionized water.

[0031] The preparation method of the composite stabilizer includes the following steps: Loaded curcumin A and pH 5.5, 0.05M acetate-sodium acetate buffer (the ratio of loaded curcumin A to phosphate buffer is 1g:10ml) were mixed and stirred for 30min to obtain liquid 1 for later use. Vitamin C palmitate and a mixture of anhydrous ethanol and glycerol were mixed (the ratio of vitamin C palmitate, anhydrous ethanol and glycerol is 1g:10ml:15ml) and stirred for 15min to obtain liquid 2 for later use. Liquid 1 and liquid 2 were mixed, and Tween 80 (0.5% of the total mass of liquid 1 and liquid 2) was added and stirred for 10min to obtain the composite stabilizer. The mass ratio of supported curcumin A to vitamin C palmitate is 1:5.

[0032] The preparation method of the traditional Chinese medicine for treating cough in this embodiment includes the following steps: Mix the herbal extract, compound stabilizer, and deionized water, stir for 30 minutes, and filter through a 0.22μm filter membrane to obtain the herbal liquid for treating cough.

[0033] Example 2 A traditional Chinese medicine for treating cough, comprising the following ingredients by weight: 80 parts of herbal extract, 0.4 parts of compound stabilizer, and 40 parts of deionized water.

[0034] The preparation method of the composite stabilizer is the same as in Example 1; The mass ratio of supported curcumin A to vitamin C palmitate is 1:3.

[0035] The preparation method of the traditional Chinese medicine for treating cough in this embodiment is the same as in Example 1.

[0036] Example 3 A traditional Chinese medicine for treating cough, comprising the following ingredients by weight: 90 parts of herbal extract, 0.8 parts of compound stabilizer, and 50 parts of deionized water.

[0037] The preparation method of the composite stabilizer is the same as in Example 1; The mass ratio of supported curcumin A to vitamin C palmitate is 1:6.

[0038] The preparation method of the traditional Chinese medicine for treating cough in this embodiment is the same as in Example 1.

[0039] Example 4 This embodiment provides a traditional Chinese medicine for treating cough, namely a cough-relieving liquid and its preparation method. The specific implementation method is the same as in embodiment 1, except that the mass ratio of loaded curcumin A and vitamin C palmitate in the composite stabilizer is 1:1.

[0040] Example 5 This embodiment provides a traditional Chinese medicine for treating cough, namely a cough-relieving liquid and its preparation method. The specific implementation method is the same as in embodiment 1, except that the mass ratio of loaded curcumin A and vitamin C palmitate in the composite stabilizer is 1:7.

[0041] Example 6 This embodiment provides a traditional Chinese medicine for treating cough, namely a cough-relieving liquid and its preparation method. The specific implementation method is the same as in embodiment 1, except that the loaded curcumin A is replaced by an equal amount of loaded curcumin B.

[0042] Example 7 This embodiment provides a traditional Chinese medicine for treating cough, namely a cough-relieving liquid and its preparation method. The specific implementation method is the same as in embodiment 1, except that the loaded curcumin A is replaced by an equal amount of loaded curcumin C.

[0043] Example 8 This embodiment provides a traditional Chinese medicine for treating cough, namely a cough-relieving liquid and its preparation method. The specific implementation method is the same as in embodiment 1, except that curcumin is used to replace the loaded curcumin A in an equal amount.

[0044] Comparative Example 1 This comparative example provides a traditional Chinese medicine for treating cough, namely a cough-relieving liquid and its preparation method. The specific implementation method is the same as in Example 1, except that the composite stabilizer is replaced by an equal amount of supported curcumin A.

[0045] Comparative Example 2 This comparative example provides a traditional Chinese medicine for treating cough, namely a cough-relieving liquid and its preparation method. The specific implementation method is the same as in Example 1, except that the compound stabilizer is replaced by an equal amount of vitamin C palmitate.

[0046] Performance testing 1. The stability of the traditional Chinese medicines in the lung-clearing and cough-relieving liquids of Examples 1-8 and Comparative Examples 1-2 was tested.

[0047] Stability was determined by testing the total antioxidant capacity of the traditional Chinese medicine in Xuanfei Zhike Liquid, using the FRAP method (ferric reduction antioxidant capacity method). The test results are shown in Table 1.

[0048] Table 1 As shown in Table 1, the total antioxidant capacity of the traditional Chinese medicine in Examples 1-3 of this invention is relatively high, indicating good stability. Examples 4-5 involve changing the ratio of the two raw materials in the composite stabilizer, while Comparative Examples 1-2 involve replacing the composite stabilizer with an equal amount of supported curcumin A or vitamin C palmitate, which reduces or eliminates the synergistic antioxidant effect between the composite stabilizers, resulting in varying degrees of reduction in the total antioxidant capacity of the traditional Chinese medicine in the lung-clearing and cough-relieving liquid. Examples 6-7 involve changing the ratio of glycyrrhizic acid and curcumin, key components in the synthesis of supported curcumin, which does not significantly improve the water solubility and stability of curcumin, thus leading to a decrease in the total antioxidant capacity of the traditional Chinese medicine in the lung-clearing and cough-relieving liquid. Example 8 involves replacing supported curcumin A with an equal amount of curcumin, which also shows poor results in terms of total antioxidant capacity.

[0049] 2. Clinical trials: 150 patients with cough were randomly divided into 3 groups of 50 each. Each group received the lung-clearing and cough-relieving liquid (as described in Examples 1-3), 25ml three times daily. Data was collected after one week of treatment. A follow-up study was conducted one month after discontinuation to assess drug dependence. The efficacy criteria were as follows: Cured: No cough, all other indicators meet the standard; Effective: Occasional coughing, but other symptoms improved; Ineffective: Symptoms did not improve; test results are shown in Table 2.

[0050] Table 2 As shown in Table 2, the traditional Chinese medicines in the lung-clearing and cough-relieving liquids in Examples 1-3 of this invention all have good cough-relieving effects and no drug dependence.

[0051] The above embodiments are only for illustrating the technical concept and features of the present invention, and are intended to enable those skilled in the art to understand the content of the present invention and implement it. They should not be used to limit the scope of protection of the present invention. All equivalent changes or modifications made in accordance with the spirit and essence of the present invention should be covered within the scope of protection of the present invention.

Claims

1. A traditional Chinese medicine for treating cough, which is a lung-activating and cough-relieving liquid, characterized in that, By weight, the traditional Chinese medicine for relieving cough and relieving cough includes the following ingredients: 80-90 parts of Chinese herbal extract, 0.4-0.8 parts of compound stabilizer, and 40-50 parts of deionized water; By weight, the traditional Chinese medicine components in the extract include: component A 18-31 parts, component B 16-77 parts, and component C 93-166 parts; Component A is a traditional Chinese medicine component containing volatile oils, component B is a traditional Chinese medicine component extracted with alcohol, and component C is a traditional Chinese medicine component extracted with water.

2. The lung-activating and cough-relieving liquid traditional Chinese medicine for treating cough according to claim 1, characterized in that, By weight, component A comprises the following raw materials: 4-6 parts ephedra, 3-5 parts asarum, 8-12 parts cinnamon twig, and 3-8 parts dried ginger.

3. The lung-activating and cough-relieving liquid traditional Chinese medicine for treating cough according to claim 1, characterized in that, By weight, component B comprises the following raw materials: 8-12 parts ants, 10-15 parts earthworms, 10-20 parts honeysuckle, 8-15 parts prunella vulgaris, and 10-15 parts spotted sword.

4. The lung-activating and cough-relieving liquid traditional Chinese medicine for treating cough according to claim 1, characterized in that, By weight, component C comprises the following raw materials: 10-20 parts of white peony root, 6-12 parts of licorice root, 8-10 parts of lepidium seed, 8-15 parts of scutellaria root, 10-15 parts of lycium root bark, 8-20 parts of artemisia annua, 5-12 parts of hawthorn fruit, 8-12 parts of mulberry bark, 10-20 parts of houttuynia cordata, 10-15 parts of schisandra fruit, and 10-15 parts of pinellia tuber.

5. The lung-activating and cough-relieving liquid traditional Chinese medicine for treating cough according to claim 1, characterized in that, The preparation method of the traditional Chinese medicine extract includes the following steps: (1) After pulverizing component A, add deionized water, soak, connect a volatile oil extractor, extract by gentle boiling for 3-4 hours, collect the volatile oil, add β-cyclodextrin, heat and stir, freeze dry to obtain the inclusion complex for later use; (2) Add an aqueous ethanol solution to component B, reflux at 60-70℃ for 2-3 times, combine the filtrates, recover the ethanol under reduced pressure, and obtain a thick paste for later use; (3) Add deionized water to component C, soak, decoct 2-3 times, combine the decoctions, concentrate, add ethanol aqueous solution, let stand at 2-5℃, filter, and obtain clear liquid for use. (4) Mix the inclusion complex from step (1), the thick paste from step (2), and the clear liquid from step (3), and stir to obtain the Chinese herbal extract.

6. The therapeutic cough relieving and lung expelling liquid traditional Chinese medicine according to claim 1, characterized in that, The preparation method of the composite stabilizer includes the following steps: The loaded curcumin and acetate-sodium acetate buffer were mixed and stirred to obtain liquid 1 for later use. The vitamin C palmitate and the mixture of anhydrous ethanol and glycerol were mixed and stirred to obtain liquid 2 for later use. Liquid 1 and liquid 2 were mixed, Tween 80 was added, and the mixture was stirred to obtain the composite stabilizer.

7. The therapeutic cough relieving and lung expelling liquid traditional Chinese medicine for cough according to claim 6, characterized in that, The mass ratio of the supported curcumin to vitamin C palmitate is 1:(3-6).

8. The lung-activating and cough-relieving liquid traditional Chinese medicine for treating cough according to claim 6, characterized in that, The preparation method of the supported curcumin includes the following steps: Glycyrrhizic acid was added to deionized water and stirred to obtain a solution for later use. Curcumin was added to the mixed solution and stirred. The solution was added and stirred. The mixture was homogenized under high pressure and distilled under reduced pressure to obtain the supported curcumin. The mixed solution is a mixture of ethanol, glycerol and deionized water.

9. The lung-activating and cough-relieving liquid traditional Chinese medicine for treating cough according to claim 8, characterized in that, The mass ratio of glycyrrhizic acid to curcumin is 1:(0.5-1).

10. A method for preparing the therapeutic cough-relieving Xuanfeizhike liquid traditional Chinese medicine of any one of claims 1-9, characterized in that, Includes the following steps: Mix the herbal extract, compound stabilizer, and deionized water, stir, and filter to obtain a cough-relieving liquid made from traditional Chinese medicine for treating cough.

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