Cosmetic composition for improving epidermal aging and application

Abstract

The invention relates to the technical field of cosmetics, particularly discloses a cosmetic composition for improving epidermal aging and application, and aims to solve the problem of poor skin improvement effect in the prior art. Comprising the following raw materials in parts by mass: a component I: 0.02 to 0.12 part of L-lactic acid, 1.0 to 4.8 parts of hydrolyzed rice protein, 0.1 to 0.7 part of a surfactant and 0.12 to 0.64 part of honey; and the component II comprises 0.03-0.13 part of propylene glycol, 0.01-0.32 part of glycerol, 0.02-0.23 part of sodium hyaluronate and 0.01-0.08 part of xanthan gum, and the cosmetic composition can improve the aging problem of the skin epidermis on multiple levels through scientific component proportioning. The component I is mainly used for removing aged cutin, deeply nourishing skin and enhancing the elasticity and luster of the skin;

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, and in particular to cosmetic combinations and applications for improving epidermal aging. Background Technology

[0002] As time goes by, the skin's epidermis quietly enters the natural aging process, manifested as increasing dryness, loss of elasticity, and the gradual appearance of fine lines and sagging. This is undoubtedly a gentle yet undeniable challenge to youthful radiance. To precisely address these signs of aging, we are committed to developing an innovative cosmetic combination that integrates deep nourishment, firming and lifting, and strengthening the skin's natural barrier function. This combination aims to deeply reverse the aging process of the epidermis through a carefully formulated, cutting-edge scientific formula, awakening the skin's inner vitality and restoring youthful radiance.

[0003] As the skin's first line of defense against external aggressors, the epidermis undergoes a particularly complex aging process. This is primarily manifested in the decline of keratinocyte division capacity, the gradual reduction in the thickness of the active epidermis, and the slowdown of the skin's self-repair mechanisms. Against this backdrop, retinoids, a scientifically proven anti-aging ingredient effective at multiple layers, not only promote collagen production in the dermis with their remarkable ability but also demonstrate extraordinary potential in improving epidermal aging, such as promoting the thickening of the active epidermis, thereby enhancing the skin's barrier function and overall health.

[0004] However, the remarkable efficacy of retinoids is accompanied by the challenge of their high instability; they are highly susceptible to degradation in formulations, affecting not only product efficacy but also increasing the difficulty of preservation and application. Therefore, our R&D team, through countless experiments and improvements, has finally overcome technical bottlenecks and successfully developed an innovative stabilization technology. This technology ensures the activity and stability of retinoids in cosmetic combinations, allowing them to fully exert their anti-aging effects while reducing irritation and enhancing the user experience.

[0005] This cosmetic combination for improving epidermal aging not only incorporates high-purity, stabilized retinoids, but also carefully combines various natural plant extracts and advanced moisturizing factors, such as hyaluronic acid, natural oils, and antioxidants, to work synergistically to deeply nourish the skin, promote cell regeneration, enhance the skin's ability to retain moisture, and effectively resist environmental damage, thus comprehensively improving the skin's firmness, radiance, and elasticity. Summary of the Invention

[0006] The purpose of this invention is to provide a cosmetic combination and application for improving epidermal aging, thereby solving the problem of poor skin improvement effects in the prior art.

[0007] To achieve the above objectives, the present invention provides the following technical solution:

[0008] A cosmetic combination that improves epidermal aging includes the following quality ingredients:

[0009] Component 1: L-lactic acid 0.02-0.12 parts, hydrolyzed rice protein 1.0-4.8 parts, surfactant 0.1-0.7 parts, honey 0.12-0.64 parts;

[0010] Component 2: Propylene glycol 0.03-0.13 parts, glycerin 0.01-0.32 parts, sodium hyaluronate 0.02-0.23 parts, xanthan gum 0.01-0.08 parts.

[0011] Based on the above technical solutions, the present invention also provides the following optional technical solutions:

[0012] In one alternative embodiment: component one comprises: 0.05-0.09 parts L-lactic acid, 2.0-3.0 parts hydrolyzed rice protein, 0.3-0.5 parts surfactant, and 0.3-0.5 parts honey;

[0013] Component 2: Propylene glycol 0.05-0.09 parts, glycerin 0.02-0.2 parts, sodium hyaluronate 0.04-0.15 parts, xanthan gum 0.02-0.05 parts.

[0014] In one alternative: Component 1 consists of 0.07 parts L-lactic acid, 2.5 parts hydrolyzed rice protein, 0.4 parts surfactant, and 0.4 parts honey;

[0015] Component 2: 0.06 parts propylene glycol, 0.13 parts glycerin, 0.08 parts sodium hyaluronate, and 0.03 parts xanthan gum.

[0016] In one alternative: the honey is purified, filtered, and dehydrated.

[0017] In one alternative: heat the honey to 60-65°C and hold for 20-30 minutes, then cool it quickly.

[0018] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0019] This cosmetic set, through its scientifically formulated ingredients, improves skin aging on multiple levels. Component one primarily removes dead skin cells, deeply nourishes the skin, and enhances its elasticity and radiance; component two focuses on providing long-lasting hydration, preventing moisture loss, and helping to repair the damaged skin barrier. After using this set, the skin will show noticeable improvement, appearing firmer, smoother, with reduced fine lines, a more refined texture, and a more even and radiant overall complexion. Furthermore, long-term use can effectively slow down the skin aging process and maintain a youthful appearance. Detailed Implementation

[0020] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.

[0021] Example 1

[0022] This invention provides a combination for improving epidermal aging, comprising the following raw materials by weight:

[0023] Component 1: L-lactic acid 0.02 parts, hydrolyzed rice protein 1.0 part, surfactant 0.1 parts, honey 0.12 parts;

[0024] Component 2: Propylene glycol 0.03 parts, glycerin 0.01 parts, sodium hyaluronate 0.02 parts, xanthan gum 0.01 parts.

[0025] The honey is purified, filtered, and dehydrated; it is then heated to 60-65°C and held for 20-30 minutes, followed by rapid cooling.

[0026] Example 2

[0027] This combination for improving epidermal aging includes the following quality ingredients:

[0028] Component 1: L-lactic acid 0.12 parts, hydrolyzed rice protein 4.8 parts, surfactant 0.7 parts, honey 0.64 parts;

[0029] Component 2: 0.13 parts propylene glycol, 0.32 parts glycerin, 0.23 parts sodium hyaluronate, and 0.08 parts xanthan gum; the honey is purified, filtered, and dehydrated; the honey is heated to 60-65℃ and held for 20-30 minutes, then rapidly cooled.

[0030] Example 3

[0031] This combination for improving epidermal aging includes the following quality ingredients:

[0032] Component 1: 0.05 parts L-lactic acid, 2.0 parts hydrolyzed rice protein, 0.3 parts surfactant, and 0.3 parts honey;

[0033] Component 2: 0.05 parts propylene glycol, 0.02 parts glycerin, 0.04 parts sodium hyaluronate, and 0.02 parts xanthan gum; the honey is purified, filtered, and dehydrated; the honey is heated to 60-65℃ and held for 20-30 minutes, then rapidly cooled.

[0034] Example 4

[0035] This combination for improving epidermal aging includes the following quality ingredients:

[0036] Component 1: 0.09 parts L-lactic acid, 3.0 parts hydrolyzed rice protein, 0.5 parts surfactant, and 0.5 parts honey;

[0037] Component 2: 0.09 parts propylene glycol, 0.2 parts glycerin, 0.15 parts sodium hyaluronate, and 0.05 parts xanthan gum; the honey is purified, filtered, and dehydrated; the honey is heated to 60-65℃ and held for 20-30 minutes, then rapidly cooled.

[0038] Example 5

[0039] This combination for improving epidermal aging includes the following quality ingredients:

[0040] Component 1: 0.07 parts L-lactic acid, 2.5 parts hydrolyzed rice protein, 0.4 parts surfactant, and 0.4 parts honey;

[0041] Component 2: 0.06 parts propylene glycol, 0.13 parts glycerin, 0.08 parts sodium hyaluronate, and 0.03 parts xanthan gum; the honey is purified, filtered, and dehydrated; the honey is heated to 60-65℃ and held for 20-30 minutes, then rapidly cooled.

[0042] Biological assays were performed on Examples 1, 2, 3, 4, and 5. Normal adult fibroblasts (PCS-201-012) were seeded at a density of 1 × 10⁴ cells in 24-well plates. Experimental groups were supplemented with 1% (w / v) of the solutions from Examples 1, 2, 3, 4, and 5, as well as Comparative Example 1. Each group was seeded in 24 wells for parallel experiments, with the medium changed every 3 days. The incubation was conducted at 37°C in a 5% CO₂ incubator. The number of growing cells was recorded daily, and the cell counts were statistically analyzed (×10⁻⁶). 4 The cell counts after 6 days of culture are shown in Table 1.

[0043] Add an equal amount of nutrient solution to Comparative Example 1;

[0044] experimental group Example 1 Example 2 Example 3 Example 4 Example 5 Comparative Example 6 initial value 7.46 7.46 7.51 7.47 7.48 7.52 Final value 13.46 12.12 13.18 13.87 15.58 8.0

[0045] Through detailed experimental verification and data analysis, the cosmetic composition meticulously developed in this application has demonstrated remarkable bioactivity and efficacy. Particularly noteworthy is its ability to significantly stimulate fibroblast proliferation, a discovery with profound implications for promoting skin repair and regeneration.

[0046] Specifically, through precise growth curve analysis, we observed that fibroblasts in the experimental group supplemented with the composition of this application exhibited a more robust logarithmic growth phase. During this crucial stage, cell division and proliferation rates significantly accelerated. After six consecutive days of culture, the number of viable cells obtained in the experimental group doubled compared to the control group without the composition of this application. This data directly demonstrates the beneficial effects of this composition in promoting cell metabolism.

[0047] Fibroblasts, as an important cell type in skin tissue, play a crucial role in maintaining skin structure, promoting wound healing, and combating the aging process through their proliferation and activation. The composition of this application accelerates fibroblast proliferation and metabolism by precisely regulating the cell growth cycle, not only infusing the skin with continuous vitality and repair capabilities but also promoting a comprehensive improvement in skin health at a deeper level.

[0048] In summary, the cosmetic composition provided in this application, with its significant effect of promoting cell metabolism, opens up new avenues for skin anti-aging, repair and regeneration.

[0049] Anti-aging test cosmetic compositions: The products from Examples 1-6 were tested using the method recommended by the equipment company to perform skin elasticity testing and detect anti-aging effects. In this example, 30 healthy volunteers were randomly divided into three groups. They used the corresponding samples or control products every morning and evening for 0 weeks, 1 week, 2 weeks, 3 weeks, and 4 weeks, respectively. The skin elasticity R2 of the test area was measured. The closer the value is to 1, the better the skin elasticity (Revisco meter RV 600 elastic fiber tissue testing probe, Courage+Khazakaelectronic GmbH (CK)).

[0050] The test areas were the left and right cheekbones, the left and right cheeks at the intersection of the tip of the nose and the pupil, and the left and right sides at the intersection of the temple and the corner of the mouth; where R2 = Ua / Uf, Uf is the maximum skin stretch; Ua is the skin recovery value when negative pressure is removed and then reapplied to the skin surface for the next continuous test. The test results are shown in Table 2;

[0051] Group / Time R2 growth rate Example 1 0.534 / 0.922 42.09％ Example 2 0.487 / 0.982 50.41％ Example 3 0.457 / 0.897 49.06％ Example 4 0.478 / 1.012 59.60％ Example 5 0.487 / 1.213 59.86％ Comparative Example 6 0.501 / 0.543 7.74％

[0052] As can be seen from the table above, cosmetic compositions containing the compositions of this application can significantly improve skin elasticity and exhibit significant anti-skin aging effects.

[0053] Biological assays were performed on Examples 1, 2, 3, 4, and 5 (components in all five examples were stored at 50°C for one month). Normal adult fibroblasts (PCS-201-012) were seeded at a density of 1 × 10⁴ cells in 24-well plates. Experimental groups were supplemented with 1% (w / v) of the solutions from Examples 1, 2, 3, 4, and 5, with 24 wells per group for parallel experiments. The medium was changed every 3 days. The incubation was conducted at 37°C in a 5% CO₂ incubator. The number of growing cells was recorded daily, and the cell count was statistically analyzed (×10⁻⁶). 4 The cell counts after 6 days of culture are shown in Table 3.

[0054] experimental group Example 1 Example 2 Example 3 Example 4 Example 5 initial value 7.35 7.47 7.49 7.52 7.45 Final value 13.24 11.18 12.16 12.57 14.98

[0055] A thorough analysis of the detailed data comparison between Tables 1 and 3 reveals that the cosmetic composition of this application retains its anti-aging properties even under extreme high-temperature conditions.

[0056] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A combination for improving epidermal aging, characterized by: Raw materials including the following components by mass: Component 1: L-lactic acid 0.02-0.12 parts, hydrolyzed rice protein 1.0-4.8 parts, surfactant 0.1-0.7 parts, honey 0.12-0.64 parts; Component 2: Propylene glycol 0.03-0.13 parts, glycerin 0.01-0.32 parts, sodium hyaluronate 0.02-0.23 parts, xanthan gum 0.01-0.08 parts.

2. The combination for improving epidermal aging according to claim 1, characterized in that, Component 1: 0.05-0.09 parts L-lactic acid, 2.0-3.0 parts hydrolyzed rice protein, 0.3-0.5 parts surfactant, and 0.3-0.5 parts honey; Component 2: Propylene glycol 0.05-0.09 parts, glycerin 0.02-0.2 parts, sodium hyaluronate 0.04-0.15 parts, xanthan gum 0.02-0.05 parts.

3. The combination for improving epidermal aging according to claim 1, characterized in that, Component 1: 0.07 parts L-lactic acid, 2.5 parts hydrolyzed rice protein, 0.4 parts surfactant, and 0.4 parts honey; Component 2: 0.06 parts propylene glycol, 0.13 parts glycerin, 0.08 parts sodium hyaluronate, and 0.03 parts xanthan gum.

4. The combination for improving epidermal aging according to claim 1, characterized in that, The honey has undergone purification, filtration, and dehydration.

5. The combination for improving epidermal aging according to claim 4, characterized in that, Heat the honey to 60-65℃ and keep it there for 20-30 minutes, then cool it quickly.

6. A non-treatment method for combating skin aging, characterized in that, Use an effective amount of the combination described in any one of claims 1-5.

7. A cosmetic product, characterized in that, It includes the combination described in any one of claims 1-5.

8. An application characterized in that, The combination of claims 1-6 for improving epidermal aging is used as a cosmetic ingredient.