COMPOSITION AND CARE PROCESS OF KERATINOUS MATERIALS

Abstract

COMPOSITION AND PROCESS FOR CARING FOR KERATINOUS MATERIALS The present invention relates to a composition comprising: (i) at least one extract of a Vaccinium plant; (ii) at least one extract of Punica granatum; and (iii) at least one extract of Cassia alata. The present invention also relates to a non-therapeutic process for caring for keratinous materials, comprising the application of said composition to the keratinous materials. Figure for the abstract: none

Description

Title of the invention: COMPOSITION AND PROCESS FOR THE CARE OF KERATINOUS MATERIALS technical field

[0001] The present invention relates to a composition. In particular, the present invention relates to a composition for the care of keratinous materials. The present invention also relates to a non-therapeutic process for the care of keratinous materials. PRIOR TECHNOLOGY

[0002] Glycation is a non-enzymatic process involving a reducing sugar (e.g., glucose or ribose) that reacts via the Maillard reaction with an amino group of an amino acid residue (such as lysine), particularly an amino acid residue of a protein, to form a Schiff base. This base, after a molecular rearrangement called the Amadori rearrangement, can lead, through a series of reactions, to cross-linking, particularly intramolecular cross-linking such as, for example, pentosidine cross-linking. These reversible reaction products then undergo irreversible oxidation, polymerization, dehydration, and cross-linking reactions to generate advanced glycation end products (AGEs).

[0003] This phenomenon increases with age. It is characterized by the appearance of glycation products, the content of which increases with age.

[0004] Protein glycation is therefore a universal phenomenon, well known in the skin, particularly for its dermal component, but which also occurs in its appendages such as nails or hair, especially on keratins and marginally in any protein system if the required conditions for glycation exist.

[0005] Human skin consists of two compartments, namely a superficial compartment (the epidermis) and a deep compartment (the dermis).

[0006] The extracellular matrix (ECM) in the dermis is the primary component of concern for glycation. Fibrous ECM proteins are composed of collagen, elastin, fibronectin, and laminin. Molecular modifications such as AGEs can become irreparable and irreversible. They can accumulate with age. The ECM is closely linked to skin aging; moreover, glycation of dermal collagen and elastin fibers contributes to stiffness and loss of elasticity, resulting in wrinkles.

[0007] It is well known that the skin results from a close association between at least two of its constituent compartments, namely the epidermis and the dermis. The interactions The differences between the dermis and the epidermis are such that it is reasonable to think that a change in one can have consequences on the other.

[0008] It can be suspected that the aging of the dermis, particularly with its glycation processes, is bound to have consequences on the associated epidermis. Thus, during skin aging, the glycation of ECM proteins should lead to modifications of the epidermis that necessarily contribute to the aging of the epidermis.

[0009] Therefore, it is desirable to have products that reduce or even inhibit the phenomenon of protein glycation. Summary of the invention

[0010] Thus, an object of the present invention is to develop a skin care composition which can effectively inhibit glycation, and consequently resist skin aging.

[0011] Another object of the present invention is to propose a non-therapeutic skin care process.

[0012] Consequently, in a first aspect, the present invention proposes a composition comprising: i. at least one extract of a Vaccinium plant; ii. at least one extract of Punica granatum; and iii. at least one extract of Cassia alata.

[0013] The inventors have now discovered that the composition of the present invention can effectively inhibit glycation.

[0014] In a second aspect, the present invention proposes a non-therapeutic process for the care of keratinous materials, comprising the application of the composition according to the first aspect of the present invention to the keratinous materials.

[0015] In a third aspect, the present invention proposes a use of the composition according to the first aspect of the present invention to provide an anti-aging effect on keratinous materials.

[0016] Other subjects and features, aspects and advantages of the present invention will be presented in the following description and, in part, will emerge from the description, or can be learned through practice of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0017] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as that commonly understood by a person skilled in the art of the present invention. When the definition of a term in this description is in conflict with the meaning commonly accepted by a person skilled in the art to which the present invention relates, the definition described herein shall apply.

[0018] In what follows and unless otherwise indicated, the limits of a range of values ​​are included in that range, in particular, in the expressions "between...and..." and "from...to...".

[0019] Moreover, the expression "at least one" used in this description is equivalent to the expression "one or more".

[0020] Throughout this application, the term "including" shall be interpreted as encompassing all the specifically mentioned features as well as optional, additional, unspecified features. As used herein, the use of the term "including" also discloses the embodiment in which no features other than the specifically mentioned features are present (i.e., "consisting of").

[0021] Unless otherwise specified, all numerical values ​​expressing a quantity of ingredients and the like used in the description and claims shall be understood as modified by the term "approximately". Consequently, unless otherwise indicated, the numerical values ​​and parameters described herein are approximate values ​​which, if necessary, may be changed according to the desired purpose.

[0022] For the purposes of the present invention, the term "keratinous materials" is intended to cover human skin and mucous membranes such as the lips. Facial skin is considered in particular according to the present invention.

[0023] In the present invention, all percentages refer, unless otherwise specified, to a percentage by weight.

[0024] According to the first aspect, the composition of the present invention comprises: i. at least one extract of a Vaccinium plant; ii. at least one Punica granatum extract; and iii. at least one extract of Cassia alata. Extracts from a Vaccinium plant

[0025] The composition of the present invention comprises at least one extract of a Vaccinium plant.

[0026] The genus Vaccinium includes more than 450 species, among which we can mention the species Vaccinium myrtillus, Vaccinium angustifollium, Vaccinium arboreum, Vaccinium arctostaphylos, Vaccinium caespitosum, Vaccinium corymbosum, Vaccinium hirsutum, Vaccinium macrocarpum, Vaccinium ovatum, Vaccinium oxycoccos, Vaccinium stamineum, Vaccinium uliginosum, Vaccinium urceolatum and Vaccinium vitis-idaea.

[0027] The extract of a Vaccinium plant can be any extract prepared from any plant material derived from at least one plant of the genus Vaccinium.

[0028] Thus, the extract of a Vaccinium plant used according to the present invention can be obtained from plant material derived from a whole plant or a portion of a plant such as leaves, stems, flowers, petals, fruit, roots or dedifferentiated cells.

[0029] Any extraction process known to a person skilled in the art can be used to prepare the extract contained in the composition according to the present invention.

[0030] Examples include aqueous extracts, alcoholic extracts or extracts using an organic solvent.

[0031] Preferably, the extract of a Vaccinium plant is chosen from extracts prepared from a material derived from at least one plant chosen from Vaccinium myrtillus, Vaccinium angustifolium, Vaccinium arboreum, Vaccinium arctostaphylos, Vaccinium caespitosum, Vaccinium corymbosum, Vaccinium hirsutum, Vaccinium macrocarpum, Vaccinium ovatum, Vaccinium oxycoccos, Vaccinium stamineum, Vaccinium uliginosum, Vaccinium urceolatum and Vaccinium vitis-idaea.

[0032] More preferably, the composition of the present invention comprises an extract of Vaccinium myrtillus.

[0033] Even more preferably, the composition of the present invention comprises an extract of Vaccinium myrtillus fruit.

[0034] Advantageously, the extract of a Vaccinium plant present in the composition of the present invention in an amount ranging from 0.001% by weight to 30% by weight, preferably from 0.01% by weight to 20% by weight, more preferably from 0.02% by weight to 10% by weight, even more preferably from 0.03% by weight to 5% by weight, most preferably from 0.05% by weight to 2% by weight, relative to the total weight of the composition. Extracts of Punica granatum

[0035] The composition of the present invention comprises at least one extract of Punica granatum.

[0036] As used herein, an extract of Punica granatum, also called Punica granatum extract, may be an extract comprising, optionally consisting essentially of, a substance of the fruiting plant species Punica granatum. The Punica granatum extract is not particularly limited to, and may comprise or be any extract or combination of extracts of Punica granatum suitable for use in the embodiments herein.

[0037] It has been reported that Punica granatum contains various bioactive components, including various phytochemicals. Punica granatum can simply be called pomegranate.

[0038] In general, the most abundant phytochemicals in pomegranate juice are polyphenols, including hydrolyzable tannins called ellagitannins, which are formed when ellagic acid and gallic acid bind to a carbohydrate to form pomegranate ellagitannins, also known as punicalagins. The red color of the juice is attributed to anthocyanins, such as delphinidin, cyanidin, and pelargonidin glycosides. Generally, an increase in juice pigmentation occurs during fruit ripening. Pomegranate peel contains high amounts of polyphenols, condensed tannins, catechins, and prodelphinidins. Pomegranate seed oil contains punicic acid, palmitic acid, stearic acid, oleic acid, and linoleic acid.

[0039] Specific examples of extracts of Punica granatum are known in the art. As such, extract of Punica granatum can be purchased or otherwise commercially obtained from various sources, prepared (for example, using any conventional extraction technique known in the art), or combinations thereof.

[0040] In some embodiments, the extract of Punica granatum is obtained by water extraction (or aqueous extraction) of plant material of Punica granatum.

[0041] In other embodiments, the extract of Punica granatum is obtained by alcohol extraction (for example, ethanol extraction) of plant material of Punica granatum.

[0042] As a person skilled in the art will understand, Punica granatum is primarily cultivated for its fruit. Thus, in various embodiments, Punica granatum extract is an extract of Punica granatum fruit. Suitable extractions include those noted above, for example, water and ethanol extractions of the fruit. The fruit may be from one or more plants and may be fresh, dried, or otherwise ripened.

[0043] The extract of Punica granatum may comprise material from any part of the plant, or combinations thereof, and is not limited to fruit extracts. For example, the extract of Punica granatum may comprise material extracted from one or more parts of a Punica granatum plant, including its root, stem, bark, rhizome, leaf, bud, flower, seed, and / or fruit. Furthermore, such extracts may be further processed (e.g., defatted, partially defatted, ground, dried, precipitated, washed, filtered, sieved, extracted, distilled, concentrated, etc.) to obtain the extract of Punica granatum. Similarly, the Punica granatum plant can be extracted in raw form or processed before extraction of the Punica granatum extract (e.g., used in raw form, in suspension, in dehydrated form, concentrated, etc.).

[0044] By way of example, certain extracts can be obtained when Punica granatum (for example, fruit) is pulverized to a uniform size in a mill. Then, the The resulting powder is extracted using a solution of water or ethanol. The solution is then filtered, and the filtrate can be concentrated under reduced pressure to give a syrup. The syrup can then be freeze-dried to dryness to obtain an extract.

[0045] The extract of Punica granatum can be used in any form, such as pure (i.e., without solvents, carrier vehicles, diluents, etc.), or disposed of in a carrier vehicle, such as a solvent or a dispersant. The carrier vehicle, if applicable, may include an aqueous solvent (e.g., water), an organic solvent, a fluid or oil, or the like, or combinations thereof. When used, the carrier vehicle will be selected based on the particular extract of Punica granatum used.

[0046] Preferably, the composition according to the present invention comprises a Punica granatum fruit extract, i.e. a Punica granatum extract comprising materials obtained (i.e. extracted) from Punica granatum fruit.

[0047] More preferably, the extract of Punica granatum is an extract of the fruit of Punica granatum.

[0048] Advantageously, the extract of Punica granatum is present in the composition of the present invention in an amount ranging from 0.001% by weight to 10% by weight, preferably from 0.002% by weight to 8% by weight, more preferably from 0.003% by weight to 5% by weight, even more preferably from 0.004% by weight to 3% by weight, most preferably from 0.005% by weight to 1% by weight, relative to the total weight of the composition. Extracts from Cassia alata

[0049] The composition of the present invention comprises at least one extract of Cassia alata.

[0050] The extracts to be used in accordance with the present invention can be prepared by known processes of extraction from plants or parts of plants. Details of suitable conventional extraction processes, such as maceration, remaceration, digestion, maceration by stirring, vortex extraction, ultrasonic extraction, countercurrent extraction, percolation, repercolation, evacolation (extraction under reduced pressure), diacolation and solid / liquid extraction under continuous reflux in a Soxhlet extractor, which are familiar to the expert and which can all be used in principle, can be found in Hager's Manual of Pharmaceutical Practice (5th edition, vol. 2, pp. 1026-1030, Springer Verlag, Berlin-Heidelberg-New York 1991).Fresh or dried plants or their parts are suitable as raw materials, although plants and / or plant parts that can be mechanically reduced and possibly defatted before extraction are normally used. All size reduction processes. Methods known to the expert, such as comminution with a bladed tool, can be used. The plant's leaves are particularly preferable for extraction.

[0051] Preferred solvents for the extraction process are organic solvents, water, or mixtures of organic solvents and water, particularly low molecular weight alcohols, esters, ethers, ketones, or halogenated hydrocarbons with varying water contents (distilled or undistilled), preferably aqueous alcoholic solutions with varying water contents. Extraction with water, methanol, ethanol, propanol, butanol and their isomers, acetone, propylene glycols, polyethylene glycols, ethyl acetate, dichloromethane, trichloromethane, and mixtures thereof is particularly preferred. The extraction process is generally carried out at 20 to 100 °C, preferably at 80 to 100 °C, and more particularly at 80 to 90 °C.In one possible embodiment, the extraction process is carried out in an inert gas atmosphere to prevent oxidation of the extract ingredients. Extraction times are selected by the expert based on the raw material, the extraction process, the extraction temperature, the solvent-to-raw material ratio, and other factors. After the extraction process, the resulting crude extracts may optionally undergo further typical steps, such as purification, concentration, and / or decolorization. If desired, the prepared extracts may be subjected, for example, to the selective removal of individual undesirable ingredients. The extraction process can be carried out to any degree but usually continues until exhaustion.Typical yields (dry matter extract, based on the quantity of raw material used) in the extraction of dried plants or parts of dried plants (optionally defatted) are in the range of 10% by weight to 20% by weight, preferably 12% by weight to 19% by weight, and more preferably 13% by weight to 16% by weight. If necessary, the extracts can then be subjected, for example, to spray drying or freeze-drying.

[0052] The extracts according to the present invention have an active substance content ranging from 5% by weight to 100% by weight, preferably from 10% by weight to 95% by weight, and more preferably from 20% by weight to 80% by weight. In the context of the present invention, the active substance content is the total sum of all the active substances present in the extract, based on the dry weight of the extract.

[0053] The extract of Cassia alata according to the present invention generally contains substances selected from flavone derivatives, more preferably kaempferol and kaempferol derivatives, tannins, coumarins, anthraquinones, free phenolic acids, and mixtures thereof, even more preferably p-hydroxybenzoic acid.

[0054] In the context of the present invention, flavone derivatives are understood to be those that can be isolated from the Cassia alata plant. More particularly, they are products of hydrogenation, oxidation, or substitution of 2-phenyl-4H-1-benzopyrane; hydrogenation may already be present at position 2,3 of the carbon chain, oxidation may already be present at position 4, and substitution products are understood as the replacement of one or more hydrogen atoms by hydroxy or methoxy groups. Consequently, this definition also encompasses flavans, flavan-3-ols (catecholamines), flavan-3,4-diols (leucoanthocyanidins), flavones, flavonols, and flavonones in the traditional sense. Particularly preferred flavone derivatives isolated from the Cassia alata plant are kaempferol and kaempferol such as kaempferol-3-O-sophoroside, kaempferol-7-rhamnoside, kaempferol-3,7-dirhamnoside.

[0055] Tannins in the context of this application are tannins that can be isolated from the plant Cassia alata. More specifically, they are polyphenols that can also be called gallotanins because they are derived from gallic acid. They are mixtures of pentadigalloyl glucose-type substances. Tannins are also substances formed by the oxidative coupling of galloyl residues in 1,2,3,4,6-pentagalloyl-D-glucose and derivatives of these substances.

[0056] In the context of this application, coumarins are understood to mean coumarins that can be isolated from the plant Cassia alata. The name coumarin is equivalent to the names cumarin, chromene-2-one, 2H-l-benzopyran-2-one, o-coumaric acid lactone, and tonka bean camphor. Coumarin is the cyclization product of coumaric acid. Coumaric acid is an ortho-hydroxycinnamic acid. In the context of this application, coumarin is also understood to include coumaric acid glucoside.

[0057] Anthraquinones in the context of this application are anthraquinones that can be isolated from the plant Cassia alata. More specifically, they are anthraquinone or oxidation or substitution products of 9,10-anthracene dione, substitution products being understood as the replacement of one or more hydrogen atoms by hydroxyl or methyl groups. Anthraquinones include, in particular, alizarin, quinizarin, chrysazine, hytsazarin, purpurin, chrysophanic acid, quinalizarin, and flavopurpurin.

[0058] In the context of this application, free phenolic acids are understood to mean those that can be isolated from the plant Cassia alata, preferably p-hydroxybenzoic acid and o-hydroxybenzoic acid or salicylic acid.

[0059] Preferably, the composition according to the present invention comprises an extract of Cassia alata leaf.

[0060] Advantageously, the extract of Cassia alata is present in the composition of the present invention in an amount ranging from 0.001% by weight to 30% by weight, preferably from 0.01% by weight to 20% by weight, more preferably from 0.02% by weight to 10% by weight, even more preferably from 0.03% by weight to 5% by weight, most preferably from 0.05% by weight to 2% by weight, relative to the total weight of the composition.

[0061] Advantageously, the weight ratio between the extract of a Vaccinium plant, the extract of Punica granatum and the extract of Cassia alata in the composition of the present invention is 0.05-5:1:0.2-20, preferably 1-5:1:1-10, more preferably 2-5:1:2-8. Aqueous phase

[0062] The composition of the present invention may include an aqueous phase.

[0063] Preferably, the aqueous phase comprises water.

[0064] Advantageously, water is present in the composition of the present invention in an amount ranging from 40% by weight to 99.99% by weight, preferably from 45% by weight to 99.99% by weight, more preferably from 50% by weight to 99.6% by weight, relative to the total weight of the composition.

[0065] Optionally, the aqueous phase comprises an organic solvent miscible with water (at room temperature at 25 °C) selected from monoalcohols, glycols and polyols having from 2 to 20 carbon atoms, such as octyldodecanol, glycerin, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, caprylyl glycol, dipropylene glycol, diethylene glycol; and mixtures thereof.

[0066] Advantageously, the aqueous phase is present in the composition of the present invention in an amount ranging from 50% by weight to 99.99% by weight, preferably from 55% by weight to 99.99% by weight, more preferably from 60% by weight to 99.6% by weight, relative to the total weight of the composition. Additional cosmetic active ingredients

[0067] The composition of the present invention may include an additional cosmetic active ingredient in addition to the cosmetic active ingredients as defined above.

[0068] A person skilled in the art can adjust the type and quantity of additional cosmetic active ingredients according to the end use of the composition according to the present invention. Additional adjuvants or additives

[0069] The composition of the present invention may also include conventional cosmetic adjuvants or additives, for example, perfumes, agents chelating agents, preservatives and bactericides, surfactants, thickeners, pH regulators, and mixtures thereof.

[0070] A person skilled in the art can choose the quantity of additional adjuvants or additives so as not to have a negative impact on the final use of the composition according to the present invention.

[0071] According to a particularly preferred embodiment, the present invention proposes a composition comprising, relative to the total weight of the composition: i. from 0.05% by weight to 2% by weight of a fruit extract of Vaccinium myrtillus; ii. from 0.005% by weight to 1% by weight of a fruit extract of Punica granatum; and iii. From 0.05% by weight to 2% by weight of a leaf extract of Cassia alata. Pharmaceutical form and process

[0072] The composition of the present invention is in the form of an emulsion, a cream, a lotion or a hydrogel, and can be used as a toner, a lotion, a serum, a light cream, a nourishing cream, a night mask or an eye cream.

[0073] The composition of the present invention can be used for the care of keratinous materials. In particular, the composition of the present invention can provide anti-aging benefits.

[0074] According to the second aspect, the present invention proposes a non-therapeutic process for the care of keratinous materials, comprising the application of the composition according to the first aspect of the present invention to the keratinous materials.

[0075] In certain embodiments, the present invention proposes a non-therapeutic anti-aging process for keratinous materials, comprising the application of the composition according to the first aspect of the present invention on the keratinous materials.

[0076] In particular, keratinous material is the skin, especially facial skin.

[0077] In a third aspect, the present invention proposes a use of the composition according to the first aspect of the present invention to provide an anti-aging effect on keratinous materials.

[0078] In particular, keratinous material is the skin, especially facial skin. EXAMPLES

[0079] The following examples are given by way of non-limiting illustrations of the present invention.

[0080] The main raw materials used, their trade names and suppliers are listed in Table 1.

[0081] [Tables 1] INCI Trade Name Supplier Vaccinium myrtillus fruit extract BLUEBERRY HERBASO L EXTRACT PG, UNPRESERVED, SYSTEM 3 LIPOID KOSMETIK Punica granatum fruit extract AMIPORINE ER ALBAN MULLER (CRODA) Cassia alata leaf extract DN-AGE PW LS 9827 BASF BEAUTY CARE SOLUTION Inventive Example 1 and Comparative Examples 1 to 6

[0082] Compositions of Inventive Example (El) 1 and Comparative Examples (EC) 1 to 6 were prepared on the basis of the quantities of ingredients given in Table 2. The quantities are given as % by weight of each active ingredient relative to the total weight of the composition.

[0083] [Tables2] Ingredients ELI EC. 1 EC. 2 EC. 3 EC. 4 EC. 5 EC. 6 Vaccinium myrtillus fruit extract 0.08 0.08 0 0 0.08 0.08 0 Punica granatum fruit extract 0.02 0 0.02 0 0.02 0 0.02 Cassia alata leaf extract 0.1 0 0 0.1 0 0.1 0.1 Water QS100

[0084] The composition of Inventive Example 1 represents a composition according to the present invention.

[0085] The compositions of Comparative Example 1 do not include an extract of Punica granatum and an extract of Cassia alata.

[0086] The composition of Comparative Example 2 does not include an extract of a Vaccinium plant and an extract of Cassia alata.

[0087] The composition of Comparative Example 3 does not include an extract of a Vaccinium plant and an extract of Punica granatum.

[0088] The composition of Comparative Example 4 does not include an extract of Cassia alata.

[0089] The composition of Comparative Example 5 does not include an extract of Punica granatum.

[0090] The composition of Comparative Example 6 does not include an extract of a Vaccinium plant.

[0091] Preparation process:

[0092] The compositions listed above were prepared as follows: adding Vaccinium myrtillus fruit extract (where applicable), Punica granatum fruit extract (where applicable) and Cassia alata leaf extract (where applicable) to a beaker, then adding water under stirring at room temperature to obtain a homogeneous mixture. Assessment

[0093] The effect of the above-prepared compositions on the inhibition of advanced terminal glycation products was tested as follows.

[0094] A mixed solution containing 80 mg / mL of bovine serum albumin and 240 mg / mL of glucose was prepared using a 0.1 mol / L phosphate buffer (PBS) solution and filtered through a 0.22 µm membrane filter for use as a glycation reaction solution 2*. The compositions listed in Table 2 were used as reaction systems. The final concentrations of bovine serum albumin and glucose in each reaction system were 40 mg / mL and 120 mg / mL, respectively.

[0095] [Table 3] AGE inhibition test systems Unit (mL) AB c D glycation reaction solution 2* 1 0 1 0 test sample / control solution 2* 1 1 0 0 PBS / solvent for test sample 0 1 1 2

[0096] The mixtures were thoroughly mixed and incubated at 55 °C for 40 hours. PBS or the sample solvent was used instead of the test samples as the negative control or solvent control, and 1% aminoguanidine hydrochloride was used as the positive control. PBS was used instead of the glycation reaction solution as the control system. After the reaction, the incubated solution was cooled to room temperature for determination, and 200 pL of the reaction solution was added to the 96-well plate. Detection was performed using a fluorescent enzyme spectrometer at an excitation wavelength of 370 nm. and at the emission wavelength of 440 nm, and the AGE inhibition rate was calculated.

[0097] The inhibition of AGEs (%) was calculated according to the following equation: [Math.l] AGE inhibition (%) = [1 - ( )] * 100

[0098] in which

[0099] A- the fluorescence intensity of the glycation system in the test group;

[0100] B- the fluorescence intensity of PBS in the test group;

[0101] C- the fluorescence intensity of the glycation system in the control group;

[0102] D- the fluorescence intensity of PBS in the control group.

[0103] The inhibition of AGEs (%) for each composition of Inventive Example 1 and Comparative Examples (CE) 1 to 6 has been summarized in Table 4.

[0104] [Tables4] ELI Properties EC. 1 EC. 2 EC. 3 EC. 4 EC. 5 EC. 6 AGE Inhibition (%) 14.27 7.07 2.89 2.27 7.63 6.96 6.40

[0105] Table 4 shows that the composition of Inventive Example 1 exhibits improved inhibition of glycation compared to the compositions of Comparative Examples 1 to 6. Therefore, the composition of Inventive Example 1 can be used to provide an anti-aging effect on keratinous materials.

Claims

Demands

1. Composition comprising: (i) at least one extract of a Vaccinium plant; (ii) at least one extract of Punica granatum; and (iii) at least one extract of Cassia alata.

2. Composition according to claim 1, in which the extract of a Vaccinium plant is chosen from extracts prepared from a material derived from at least one plant chosen from Vaccinium myrtillus, Vaccinium angustifolium, Vaccinium arboreum, Vaccinium arctostaphylos, Vaccinium caespitosum, Vaccinium corymbosum, Vaccinium hirsutum, Vaccinium macrocarpum, Vaccinium ovatum, Vaccinium oxycoccos, Vaccinium stamineum, Vaccinium uliginosum, Vaccinium urceolatum and Vaccinium vitis-idaea.

3. Composition according to any one of claims 1 to 2, wherein the extract of a Vaccinium plant is present in an amount from 0.001% by weight to 30% by weight, preferably from 0.01% by weight to 20% by weight, more preferably from 0.02% by weight to 10% by weight, even more preferably from 0.03% by weight to 5% by weight, most preferably from 0.05% by weight to 2% by weight, relative to the total weight of the composition.

4. Composition according to any one of claims 1 to 3, wherein the extract of Punica granatum comprises materials extracted from one or more parts of a Punica granatum plant, including the root, stem, bark, rhizome, leaf, bud, flower, seed and / or fruit thereof.

5. Composition according to any one of claims 1 to 4, wherein the extract of Punica granatum is present in an amount from 0.001% by weight to 10% by weight, preferably from 0.002% by weight to 8% by weight, more preferably from 0.003% by weight to 5% by weight, even more preferably from 0.004% by weight to 3% by weight, most preferably from 0.005% by weight to 1% by weight, relative to the total weight of the composition.

6. A composition according to any one of claims 1 to 5, wherein the Cassia alata extract comprises substances selected from the group consisting of flavone derivatives, more preferably kaempferol and kaempferol derivatives, tannins, coumarins, anthraquinones, free phenolic acids, and mixtures thereof, even more preferentially p-hydroxybenzoic acid.

7. A composition according to any one of claims 1 to 6, wherein the extract of Cassia alata is present in an amount from 0.001% by weight to 30% by weight, preferably from 0.01% by weight to 20% by weight, more preferably from 0.02% by weight to 10% by weight, even more preferably from 0.03% by weight to 5% by weight, most preferably from 0.05% by weight to 2% by weight, relative to the total weight of the composition

8. Composition according to claim 1, comprising, in relation to the total weight of the composition: (i) 0.05% by weight to 2% by weight of a fruit extract of Vaccinium myrtillus; (ii) 0.005% by weight to 1% by weight of a fruit extract of Punica granatum; and (iii) 0.05% by weight to 2% by weight of a leaf extract of Cassia alata.

9. Non-therapeutic process for the care of keratinous materials, comprising the application of the composition according to any one of claims 1 to 8 on keratinous materials.

10. Use of the composition according to any one of claims 1 to 8 to provide an anti-aging effect on keratinous materials.