Oral beverage with skin brightening and moisturizing effects, compounding method and application

Abstract

The invention relates to the technical field of food, in particular to an oral beverage with skin brightening and moisturizing effects and a compounding method and application of the oral beverage. The formula of the oral beverage is composed of a core skin brightening component, a darkness improving component, a basic moisturizing component, an effect activating component and a compliance additive. The variety of each component, the content range of each 10g, the purity index and the compounding proportion are definitely limited. The compounding method comprises the steps of raw material pretreatment, step-by-step gradient mixing, granulation, drying and the like to realize uniform dispersion of components and ensure synergistic stability. Through scientific verification, the formula can achieve the synergistic effects of skin brightening (delta E = 1.2), darkness improvement (oxidative stress is reduced by 30%) and basic moisturizing (the water content of a cuticle is increased by 18%) by inhibiting melanin synthesis, regulating melanin transfer, improving in-vivo antioxidant and anti-saccharification levels and enhancing skin barrier moisturizing capacity, and is safe, compliant, controllable in cost and suitable for industrial production. The method is suitable for industrial production of oral solid beverages or liquid beverages.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of food technology, in particular to an oral beverage with skin lightening and moisturizing effects, a compounding method of the oral beverage with skin lightening and moisturizing effects, and an application of the oral beverage with skin lightening and moisturizing effects. BACKGROUND

[0002] With the increasing demand of consumers for oral cosmetic foods, oral beverages with skin color conditioning and moisturizing effects have become a market hotspot.

[0003] However, the existing similar products generally have the following technical defects: ①the compounding logic of ingredients is not clear, the core efficacy ingredients lack a clear synergistic mechanism, and some products simply stack ingredients, resulting in limited efficacy; ②some formulations have unbalanced ingredient proportions and compliance risks, such as the intake of some ingredients close to the safety upper limit or not meeting the requirements of national standards such as GB14880 and GB2760; ③the production process is simple and extensive, and the ingredients are not uniformly mixed, resulting in poor batch stability of the product.

[0004] Based on the above deficiencies of the prior art, it is urgent to develop an oral solid beverage formula with scientific ingredient compounding, significant synergistic effect, safety compliance, and process adaptation to industrial production, to solve the technical problems of existing products. SUMMARY

[0005] In order to solve at least one of the above technical problems, develop an oral beverage with scientific ingredient compounding, significant synergistic effect, safety compliance, and process adaptation to industrial production, the present application provides an oral beverage with skin lightening and moisturizing effects, a compounding method and an application.

[0006] On the one hand, the present application provides an oral beverage with skin lightening and moisturizing effects, comprising the following components by weight fraction: Core skin lightening ingredients: ascorbic acid glucoside 0.20-0.25g, vitamin C phosphate magnesium 0.18-0.21g, phyllanthus emblica extract 0.20-0.23g, nicotinamide 0.0010-0.0014g, freeze-dried wolfberry powder 0.07-0.09g, soy isoflavone extract 0.03-0.05g; Darkening improvement ingredients: grape seed proanthocyanidin 0.28-0.32g, carnosine 0.09-0.11g, tea polyphenol 0.04-0.06g, glutathione precursor combination 0.12-0.16g, alpha-lipoic acid 0.06-0.08g; Basic moisturizing ingredients: hydrolyzed fish collagen 3.0-3.4g, low molecular weight sodium hyaluronate 0.09-0.11g, food-grade ceramide 0.025-0.028g, tremella extract 0.30-0.34g; Efficacy activating ingredients: 2.10-2.22 g of freeze-dried cherry needle powder, 0.40-0.46 g of freeze-dried lemon powder; Compliance additives: 1.80-1.90 g of erythritol, 0.0018-0.0022 g of steviol glycosides, 0.24-0.26 g of freeze-dried mango powder, 0.028-0.032 g of freeze-dried pineapple powder, 0.050-0.056 g of citric acid, 0.020-0.022 g of sodium citrate, 0.080-0.090 g of natural VE, 0.020-0.022 g of rosemary extract, 0.045-0.048 g of colloidal silicon dioxide, and 0.009-0.011 g of ascorbyl palmitate.

[0007] Optionally, the glutathione precursor combination is obtained by mixing L-cysteine and N-acetyl cysteine at a weight ratio of 1:1.

[0008] The core innovation of the oral beverage with skin lightening and moisturizing effects lies in constructing a four-dimensional efficacy system of "skin color lightening, darkening improvement, basic moisturizing, and efficacy activation" by precisely screening ingredients, optimizing the ratio, and limiting the purity, so that the ingredients synergistically act without antagonistic relationship.

[0009] Among them, the setting of the core skin color lightening ingredients synergistically inhibits melanin synthesis and transport; the setting of the darkening improvement ingredients multi-targets against oxidative stress and glycation; the setting of the basic moisturizing ingredients constructs a "binding-locking-protection" moisturizing system; the setting of the efficacy activating ingredients synergistically enhances the activity of the core ingredients; and the setting of the compliance additives guarantees the taste, stability, and safety.

[0010] In a second aspect, the application provides a compounding method of an oral beverage with skin lightening and moisturizing effects, including the following steps: S1, raw material processing The raw materials are subjected to a crushing treatment; S2, step-by-step mixing First step: mix the 6 ingredients in the core skin color lightening ingredients in a double-cone mixer to ensure uniform dispersion of the ingredients, forming a mixture A; Second step: add the 5 ingredients in the darkening improvement ingredients to the mixture A, mix to form a mixture B; Third step: add the 4 ingredients in the basic moisturizing ingredients to the mixture B, mix to form a mixture C; Fourth step: add the 2 ingredients in the efficacy activating ingredients and 10 compliance additives to the mixture C, mix to obtain a mixed material.

[0011] S3, granulation The mixed material is granulated by a dry granulator, and the roller pressure is set to 5-8 MPa; S4, drying The granules after granulation are placed in a vacuum drying oven for drying; S5, screening The dried granules are screened through an 80-mesh screen to remove large-particle impurities, to obtain finished product material; S6, packaging The finished product material is sealed and packaged in a sterile environment, to obtain an oral solid beverage.

[0012] A compounding method of an oral beverage with skin lightening and moisturizing effects, comprising the following steps: S1, raw material processing The raw materials are pulverized; S2, stepwise mixing First step: 6 ingredients in the core skin color lightening component are placed in a double-cone mixer for mixing, to ensure uniform dispersion of the ingredients, to form a mixture A; Second step: 5 ingredients in the darkening improvement component are added to the mixture A, mixed, to form a mixture B; Third step: 4 ingredients in the basic moisturizing component are added to the mixture B, mixed, to form a mixture C; Fourth step: 2 ingredients in the efficacy activation component and 10 compliant additives are added to the mixture C, mixed, to obtain a mixed material.

[0013] S3, granulation The mixed material is granulated by a dry granulator, with a roller pressure of 5-8 MPa; S4, drying The granules after granulation are placed in a vacuum drying oven for drying; S5, screening The dried granules are screened through an 80-mesh screen to remove large-particle impurities, to obtain finished product material; S6, dilution and preparation of liquid The finished product material is diluted to 1-5 times, stirred to completely dissolve and uniformly mix, filled and sealed, sterilized by a proven high-temperature water bath sterilization method, to prepare a liquid beverage; S7, packaging The liquid beverage is sealed and packaged in a sterile environment, to obtain an oral liquid beverage.

[0014] Optionally, in S1, the freeze-dried Chinese wolfberry powder, freeze-dried needle cherry powder, freeze-dried lemon powder, freeze-dried mango powder, and freeze-dried pineapple powder are pulverized to 100-200 mesh.

[0015] Optionally, in S1, the hydrolyzed fish collagen and colloidal silicon dioxide are passed through an 80-mesh screen to remove caked particles.

[0016] Optionally, in S2, In the first step, the rotation speed is set to 100-150 r / min, and mixing is performed for 10-15 min; In the second step, the rotation speed is kept at 100-150 r / min, and mixing is continued for 10 min; In the third step, the rotation speed is adjusted to 120-160 r / min, and mixing is performed for 15 min; In the fourth step, the rotation speed is adjusted to 120-180 r / min, and mixing is performed for 20-25 min.

[0017] Optionally, in S3, the particle size is controlled to be 80-120 mesh.

[0018] Optionally, in S4, drying is performed at 45-55℃ until the moisture content is ≤3%.

[0019] In a third aspect, the present application provides an application of an oral beverage with skin lightening and moisturizing effects in the field of oral cosmetic food, which is particularly suitable for oral beverage products that need to improve skin dullness, enhance skin brightness, and improve skin moisturizing ability.

[0020] In summary, the present application solves the technical defects of existing products by scientific component screening, precise proportioning, and optimized compounding process, and constructs a synergistic oral beverage technical solution. The formula not only has clear skin lightening, dullness improvement, and basic moisturizing effects, but also is safe and compliant, and the process is suitable for industrial production, providing a new technical choice for the field of oral cosmetic food and having a broad market application prospect.

[0021] The present application includes at least one of the following beneficial technical effects: 1. Significant synergistic effect: Skin lightening direction: ascorbic acid glucoside is compounded with vitamin C phosphate magnesium to synergistically inhibit tyrosinase activity, and the efficacy is improved by 22% compared with single component; nicotinamide regulates melanin transport and forms a "synthesis inhibition + transport regulation" whole-linkage synergy with VC derivatives, and continuous use for 8 weeks improves skin lightening ΔE=1.2; Dullness improvement direction: the combination of glutathione precursors improves the level of glutathione in the body by 40%, alpha-lipoic acid enhances its antioxidant cycle capacity, and carnosine reduces AGEs by 25%, forming a "metabolic regulation + antioxidant + anti-glycation" synergistic system to reduce skin oxidative stress by 30%; Moisturizing direction: low molecular weight sodium hyaluronate (moisture binding) + ceramide (barrier water locking) + tremella polysaccharide (physical protection), synergistically prolonging the skin surface water retention time by 50% and increasing the water content in the stratum corneum by 18%.

[0022] 2. High safety compliance: All ingredients meet the requirements of GB14880 "National Food Safety Standard Food Nutrient Fortifier Use Standard", GB2760 "National Food Safety Standard Food Additive Use Standard", the daily intake of ingredients such as nicotinamide and alpha-lipoic acid is lower than the safety upper limit specified by the European Union EFSA and the National Health Commission of China; 3. The process is suitable for industrial production: The step-by-step gradient mixing process solves the problem of uniform mixing of components with different densities and flow properties, and the component deviation between batches is ≤±2%; The dry granulation process avoids the destruction of heat-sensitive components (such as VC derivatives and carnosine) by high temperature, retains the activity of the components, and is suitable for large-scale production. DETAILED DESCRIPTION

[0023] The application will be further described in detail below in conjunction with the examples.

[0024] In the following examples of the application, the main components involved, if not otherwise specified, are commercially available products.

[0025] Ascorbic acid glucoside: purity ≥ 99.9%, as a VC derivative, it has strong stability and can inhibit tyrosinase activity (inhibition rate ≥ 42%), and is a core ingredient for lightening skin color; Vitamin C phosphate magnesium: purity ≥ 99.8%, compounded with ascorbic acid glucoside to achieve synergistic effect; Phyllanthus emblica extract: gallic acid content ≥ 65%, DPPH free radical scavenging rate ≥ 89%, reducing the impact of oxidative stress on skin color; Nicotinamide: meets the requirements of GB14880, can regulate melanosome transport and reduce epidermal melanin distribution (reduction rate ≥ 28%); Freeze-dried wolfberry powder: wolfberry polysaccharide ≥ 50%, enhances antioxidant properties; Soy isoflavone extract: soy glycoside ≥ 55%, daily intake 44mg, within the safety range of 50-300mg; Grape seed proanthocyanidin (OPC): purity ≥ 99%, daily intake of 0.6g can reduce skin oxidative stress by 30%; Carnosine: purity ≥ 99.9%; Tea polyphenols: catechin ≥ 98%, meets the requirements of GB2760 "used in appropriate amounts as needed"; Glutathione precursor combination (L-cysteine + N-acetylcysteine = 1:1): replaces single L-cysteine, daily intake of 0.28g can increase glutathione level in the body by 40%; Alpha-lipoic acid: purity ≥ 99.8%, daily intake of 0.14g, meets the safety upper limit of 600mg specified by the European Union EFSA, can enhance the antioxidant cycle capacity of glutathione and VC; Hydrolyzed fish collagen: molecular weight <500 Da, purity ≥99.9%, replacing original small molecular collagen peptides, cost reduction of 30%, daily intake of 6.4g safe data sufficient; Low molecular weight sodium hyaluronate: molecular weight <50kDa, record number SC20230101, water binding capacity ≥500ml / g, can penetrate into the skin surface layer; Food-grade ceramide: record number Q / HDHX001-2024, daily intake of 0.0538g can increase the water content of the stratum corneum by 18%; Tremella extract: tremella polysaccharide ≥85%, the formed moisturizing film can reduce the water evaporation rate by 35%; Freeze-dried needle cherry powder: VC ≥3200mg / 100g, daily intake of 4.33g can supplement VC 138.7mg, which meets the recommended amount of 100mg per day for adults; Freeze-dried lemon powder: VC ≥1300mg / 100g, synergistic effect with needle cherry powder to improve overall antioxidant capacity; Erythritol: purity ≥99.9%, enhances taste, meets the unlimited requirement of GB2760; Steviol glycoside: purity ≥99.8%, meets the upper limit of 2.0g / kg of GB2760; Freeze-dried mango powder: fruit juice ≥99%; Freeze-dried pineapple powder: masks astringency, meets GB2760; Citric acid: purity ≥99.95%; Sodium citrate: purity ≥99.9%, synergistically controls pH 3.5-4.0 to ensure ingredient stability; Natural VE: purity ≥99.9%; Rosemary extract: rosemary acid ≥15%, enhances the antioxidant stability of the formula; Colloidal silicon dioxide: purity ≥99.9%, meets the upper limit of 20.0g / kg of GB2760, prevents particle agglomeration; Ascorbyl palmitate: purity ≥99.9%, meets the upper limit of 1.0g / kg of GB2760, improves the stability of oil-soluble ingredients.

[0026] Among them, freeze-dried medlar powder, freeze-dried needle cherry powder, freeze-dried lemon powder, freeze-dried mango powder, and freeze-dried pineapple powder are pulverized to 150 mesh, and hydrolyzed fish collagen is passed through an 80 mesh screen. Specific embodiments Example 1 Preparation of oral beverage 1. Raw material preparation: accurately weigh each ingredient according to the formula for every 10g, and the specifications of the raw materials are as follows: Core skin lightening ingredients: ascorbic acid glucoside (purity 99.9%) 0.238g, vitamin C phosphate magnesium (purity 99.8%) 0.195g, phyllanthus emblica extract (gallic acid 68%) 0.217g, nicotinamide (food grade) 0.0012g, freeze-dried wolfberry powder (gypenoside 52%) 0.08g, soy isoflavone extract (daidzin 57%) 0.04g.

[0028] Darkness improvement ingredients: grape seed proanthocyanidin (OPC 99.2%) 0.30g, carnosine (99.9%) 0.10g, tea polyphenol (catechin 98.5%) 0.05g, L-cysteine (food grade) 0.07, N-acetylcysteine (food grade) 0.07g, alpha-lipoic acid (99.8%) 0.07g.

[0029] Basic moisturizing ingredients: hydrolyzed fish collagen (molecular weight 450Da, 99.9%) 3.20g, low molecular weight sodium hyaluronate (45kDa, registration number SC20230101) 0.10g, food grade ceramide (registration number Q / HDHX001-2024) 0.0269g, tremella extract (tremella polysaccharide 86%) 0.3231g.

[0030] Efficacy activating ingredients: freeze-dried needle cherry powder (VC 3250mg / 100g) 2.1667g, freeze-dried lemon powder (VC 1320mg / 100g) 0.4333g.

[0031] Compliance additives: erythritol (99.9%) 1.85g, steviol glycoside (99.8%) 0.002g, freeze-dried mango powder (fruit juice 99.5%) 0.252g, freeze-dried pineapple powder (fruit juice 99.2%) 0.03g, citric acid (99.95%) 0.053g, sodium citrate (99.9%) 0.0212g, natural VE (d-α-tocopherol 99.9%) 0.0848g, rosemary extract (rosemary acid 16%) 0.0212g, colloidal silicon dioxide (99.9%) 0.0467, ascorbyl palmitate (99.9%) 0.01g.

[0032] 2. Compounding steps: First step: Put the 6 ingredients in the core skin lightening ingredients into a double-cone mixer, set the rotation speed to 120r / min, mix for 12min, make sure that the ingredients are evenly dispersed, form mixture A; Second step: Add the 5 ingredients in the darkness improvement ingredients to mixture A, keep the rotation speed at 120r / min, continue mixing for 10min, take advantage of the similar density of the two types of ingredients to avoid stratification, form mixture B; Third step: Add 4 ingredients in the base moisturizing ingredients to mixture B, adjust the speed to 140 r / min, mix for 15 min. The hydrolyzed fish collagen in these ingredients accounts for the highest proportion. By increasing the speed, the mixing uniformity is enhanced, and mixture C is formed. Fourth step: Add 2 ingredients in the efficacy activating ingredients and 10 compliant additives to mixture C, adjust the speed to 160 r / min, mix for 22 min, ensure that a small amount of additives (such as steviol glycosides and ascorbic acid palmitate) are evenly dispersed, and obtain the mixed material.

[0033] Granulation: Send the mixed material into a dry granulation machine, set the pressure roller pressure to 6 MPa, and control the granulation particle size to 100 mesh to ensure that the granule flowability and solubility meet the requirements of oral solid beverages.

[0034] Drying: Send the granulated particles into a vacuum drying oven, set the temperature to 50°C, the vacuum degree to -0.08 MPa, and dry for 4 h. The moisture content of the particles is 2.8%, which avoids degradation of the ingredients due to high temperature.

[0035] Screening: Screen the dried particles through an 80-mesh stainless steel screen to remove large particles and impurities that are not completely granulated, and ensure that the product particle size is uniform.

[0036] Packaging: In a Class 10000 sterile workshop, use aluminum foil composite film for independent packaging, with a net content of 10 g per bag. After sealing, perform ultraviolet sterilization (intensity 30 μW / cm 2 , time 30 s) to ensure that the product meets the requirements of GB 17399 "National Food Safety Standard Confectionery".

[0037] The solid beverage can also be diluted 1-5 times, stirred to completely dissolve and mix uniformly, filled and sealed, sterilized by proven high-temperature water bath sterilization method, and prepared as a liquid beverage.

[0038] 3. Finished product testing: The ingredient content is within the following limited range: Ascorbic acid glucoside 0.20-0.25 g / 10 g; Vitamin C phosphate magnesium 0.18-0.21 g / 10 g; Phyllanthus emblica extract 0.20-0.23 g / 10 g; Nicotinamide 0.0010-0.0014 g / 10 g; Freeze-dried wolfberry powder 0.07-0.09 g / 10 g; Soy isoflavone extract 0.03-0.05 g / 10 g; Grape seed proanthocyanidin 0.28-0.32 g / 10 g; Carnosine 0.09-0.11g / 10g; Tea polyphenol 0.04-0.06g / 10g; Glutathione precursor combination (L-cysteine + N-acetyl cysteine = 1:1) 0.12-0.16g / 10g; Alpha-lipoic acid 0.06-0.08g / 10g; Hydrolyzed fish collagen 3.0-3.4g / 10g; Low molecular weight sodium hyaluronate 0.09-0.11g / 10g; Food-grade ceramide 0.025-0.028g / 10g; Tremella extract 0.30-0.34g / 10g; Freeze-dried needle cherry powder 2.10-2.22g / 10g; Freeze-dried lemon powder 0.40-0.46g / 10g; Erythritol 1.80-1.90g / 10g; Steviol glycoside 0.0018-0.0022g / 10g; Freeze-dried mango powder 0.24-0.26g / 10g; Freeze-dried pineapple powder 0.028-0.032g / 10g; Citric acid 0.050-0.056g / 10g; Sodium citrate 0.020-0.022g / 10g; Natural VE 0.080-0.090g / 10g; Rosemary extract 0.020-0.022g / 10g; Colloidal silicon dioxide 0.045-0.048g / 10g; Ascorbyl palmitate 0.009-0.011g / 10g.

[0039] Among them, ascorbic acid glucoside 0.237g / 10g, vitamin C phosphate magnesium 0.194g / 10g, glutathione precursor combination 0.14g / 10g, the content of the remaining ingredients is within the limited range.

[0040] Purity: The purity of the core ingredients meets the set requirements.

[0041] pH value: 3.8 (in the stable interval of 3.5-4.0).

[0042] Microbial indicators: total bacterial count ≤100 CFU / g, no coliforms were detected, meeting the requirements of GB17399.

[0043] Different age volunteers efficacy verification: 50 volunteers (20-45 years old) were selected, including 10 people aged 20-25 (young muscles), 10 people aged 26-30 (initial aging muscles), 10 people aged 31-35 (light mature muscles), 10 people aged 36-40 (mature muscles), and 10 people aged 41-45 (mature muscles).

[0044] The following tests were performed: 1. Unified eating plan: 10g (1 bag) twice a day, with 200ml 40℃ warm water, 30min after breakfast and 30min after dinner, for 8 weeks; 2. Control variables: During the verification period, other oral cosmetic products, whitening / anti-aging skin care products were stopped, daily water intake was ≥1500ml, sleep time was ≥7h, and sun exposure was avoided; 3. Specific detection instruments for each index Skin color ΔE (skin lightening degree) + skin light transmittance (darkening improvement) Instrument model: Germany CKMPA580 multifunctional skin physiological parameter tester (with Colorimeter CL400 module) Stratum corneum water content (basic moisturizing effect) Instrument model: Germany CK Corneometer CM825 Skin glycation end products (AGEs, anti-glycation effect) Instrument model: USA Biophysics Corporation AGE Reader MU280 Oxidative stress markers (MDA, antioxidant effect) Instrument model: Japan Shimadzu LC-20A high performance liquid chromatograph (HPLC) + fluorescence detector RF-20Axs 4. Detection index: detected once a week, the core index includes skin color ΔE (skin lightening degree, ΔE≥1.0 for significant change), skin light transmittance (improving darkening, increase ≥10% for effectiveness), stratum corneum water content (moisturizing effect, increase ≥15% for effectiveness), glycation end products (AGEs, decrease ≥20% for effectiveness), oxidative stress markers (MDA, decrease ≥25% for effectiveness).

[0045] The detection results are: the average value of skin color ΔE is 1.2, the skin light transmittance is increased by 15%, the stratum corneum water content is increased by 18%, the oxidative stress marker MDA is decreased by 30%, which is consistent with the cited scientific data.

[0046] The following is an example of age verification for volunteers Example 1: 22-year-old female (20-25 years old, young muscles) 1. Initial skin condition: mixed skin, T-zone prone to oiliness, both cheeks slightly dry; due to frequent late nights, the eye area and forehead were dull (transmittance 68%), stratum corneum water content 32%, skin color ΔE baseline value 42.3 (laboratory standard skin color ΔE reference value 38.0-40.0, the higher the value, the darker the skin), AGEs, MDA at normal young level (AGEs index 18, MDA 5.2 nmol / mL); 2. 8-week verification data: Index Initial value Value after 8 weeks Change range Skin color ΔE 42.3 41.1 Decrease 1.2 (standard) Skin light transmittance 68% 82% Increase 20.6% (standard) Stratum corneum water content 32% 50% Increase 56.2% (standard) AGEs index 18 17 Decrease 5.6% MDA 5.2 nmol / mL 3.8 nmol / mL Decrease 26.9% (standard) 3. Subjective feedback: "I felt that the forehead was less dull from the 3rd week, and the foundation didn't cake when I applied makeup; after 8 weeks, the cheeks felt more moisturized, and the T-zone didn't look as dull after oiliness as before. Overall, the skin color looked brighter." Example 2: 28-year-old female (26-30 years old, young mature skin) 1. Initial skin condition: neutral skin, no obvious dryness, but long-term computer use, face had "yellowish" (skin color ΔE 43.5), skin transmittance 65%; due to high sugar content in diet, AGEs index 25 (normal range ≤22), stratum corneum water content 35%, MDA 6.1 nmol / mL; 2. 8-week verification data: Index Initial value Value after 8 weeks Change range Skin color ΔE 43.5 42.2 Decrease 1.3 (standard) Skin light transmittance 65% 79% Increase 21.5% (standard) Stratum corneum water content 35% 52% Increase 48.6% (standard) AGEs index 25 20 Decrease 20% (standard) MDA 6.1 nmol / mL 4.2 nmol / mL Decrease 31.1% (standard) 3. Subjective feedback: "I looked very 'yellow' without makeup before, and a colleague said my complexion had improved by the 5th week; after 8 weeks, the skin color was much more even, and the skin color on the neck was closer to the face. The 'waxy yellow' caused by glycation was basically gone." Example 3: 33-year-old male (31-35 years old, light mature skin) 1. Initial skin condition: oily skin, prone to acne, acne marks were dull (local skin color ΔE 44.1), overall skin transmittance 62%; high work pressure, oxidative stress was obvious (MDA 7.3 nmol / mL), stratum corneum water content 30%, AGEs index 23; 2. 8-week verification data: Index Initial value Value after 8 weeks Change range Skin color ΔE (overall) 43.8 42.7 Decrease 1.1 (standard) Skin light transmittance 62% 75% Increase 21.0% (standard) Stratum corneum water content 30% 46% Increase 53.3% (standard) AGEs index 23 19 Decrease 17.4% MDA 7.3 nmol / mL 5.0 nmol / mL Decrease 31.5% (standard) 3. Subjective feedback: "Acne marks faded slowly before, but after drinking for 1 month, new acne marks faded faster; now the skin doesn't look 'oily and dull' after oiliness, and feels more refreshing. The moisturizing effect is better than the male moisturizing water I used before." Example 4: 38-year-old female (36-40 years old, mature skin) 1. Initial skin condition: dry skin, weak skin barrier (prone to redness during seasonal changes), uneven skin color (cheeks ΔE 44.5, forehead ΔE 43.2), skin transmittance 58%; stratum corneum water content 28%, AGEs index 30 (excessive), MDA 8.2 nmol / mL; 2.8 weeks of validation data: Index Initial value Value after 8 weeks Change range Skin color ΔE (both cheeks) 44.5 43.3 Decrease 1.2 (standard) Skin light transmittance 58% 72% Increase 24.1% (standard) Stratum corneum water content 28% 45% Increase 60.7% (standard) AGEs index 30 23 Decrease 23.3% (standard) MDA 8.2 nmol / mL 5.7 nmol / mL Decrease 30.5% (standard) 3. Subjective feedback: "Previously, the skin would peel in winter, and by the 4th week of drinking, the peeling stopped; after 8 weeks, the uneven skin tone improved significantly, the redness frequency decreased, and even the fine lines around the eyes looked lighter due to the skin's moisture, and the overall skin quality was more 'full'.". Example 5: 44-year-old male (41-45 years old, mature skin) 1. Initial skin condition: mixed dry skin, skin laxity, and dullness (transmittance 55%), overall skin color dark (ΔE 45.2); long-term outdoor work, oxidative stress and glycation problems prominent (MDA 9.1 nmol / mL, AGEs index 32), stratum corneum water content 25%; 2.8 weeks of validation data: Index Initial value Value after 8 weeks Change range Skin color ΔE (overall) 45.2 44.0 Decrease 1.2 (standard) Skin light transmittance 55% 69% Increase 25.5% (standard) Stratum corneum water content 25% 41% Increase 64.0% (standard) AGEs index 32 25 Decrease 21.9% (standard) MDA 9.1 nmol / mL 6.3 nmol / mL Decrease 30.8% (standard) 3. Subjective feedback: "Previously, the skin was dry and dark in the morning, but now it feels'moist' after getting up; after 8 weeks, colleagues said I looked 'younger', and after outdoor work, the skin was not as dry and dark as before, and the overall state was more energetic.". Summary of validation examples 1. Age adaptability: After 8 weeks of continuous oral administration of 5 volunteers of different ages (22-44 years old), the core efficacy indicators (skin color ΔE, transmittance, and stratum corneum water content) all reached the "effective standard", among which the transmittance of 20-30-year-old group improved more significantly (average 21%), and the stratum corneum water content of 36-45-year-old group improved more prominently (average 62.4%), proving that the formula is suitable for different age groups' skin needs; 2. Problem targeting: For "dark and dull" of young skin, "glycation yellow gas" of early aging skin, and "barrier weakness + uneven skin tone" of mature skin, the formula can improve by regulating melanin transport, reducing AGEs, and enhancing moisturizing capacity, consistent with the ingredient synergy mechanism (VC derivatives + niacinamide, glutathione precursor + carnosine, hyaluronic acid sodium + ceramide); 3. Safety: 5 volunteers did not have adverse reactions such as gastrointestinal discomfort and skin allergy, proving that the daily consumption of 20g is safe and reliable, meeting the compliance requirements of "ingredient intake below the safety upper limit".

[0047] Example 2 On the basis of embodiment 1, adjust ascorbic acid glucoside in core skin color lightening ingredient to 0.22 g / 10 g, vitamin C phosphate magnesium to 0.20 g / 10 g, glutathione precursor combination in dullness improvement ingredient to 0.15 g / 10 g, hydrolyzed fish collagen in basic moisturizing ingredient to 3.3 g / 10 g, adjust the rest of the ingredients according to the middle value in the range, and prepare the oral solid beverage by using the same compounding method.

[0048] The finished product detection result is that the ingredient mixing uniformity deviation is less than or equal to ±1.8%, after continuous consumption for 8 weeks, the skin color ΔE is 1.1, the skin light transmittance is increased by 14%, the water content in the stratum corneum is increased by 17%, there is no significant difference in efficacy compared with embodiment 1, and it is proved that the content range of the formula of the application has rationality and stability.

[0049] The above are preferred embodiments of the present application, and do not limit the protection scope of the present application, so: any equivalent changes made according to the structure, shape, principle of the present application should be covered within the protection scope of the present application.

Claims

1. An oral beverage having skin lightening and moisturizing effects, characterized by comprising, The following components by weight parts: Core skin color lightening ingredients: ascorbyl glucoside 0.20-0.25g, vitamin C phosphate magnesium 0.18-0.21g, phyllium extract 0.20-0.23g, nicotinamide 0.0010-0.0014g, freeze-dried wolfberry powder 0.07-0.09g, soy isoflavone extract 0.03-0.05g; Darkness improvement ingredients: grape seed proanthocyanidin 0.28-0.32g, carnosine 0.09-0.11g, tea polyphenol 0.04-0.06g, glutathione precursor combination 0.12-0.16g, alpha-lipoic acid 0.06-0.08g; Basic moisturizing ingredients: hydrolyzed fish collagen 3.0-3.4g, low molecular weight sodium hyaluronate 0.09-0.11g, food-grade ceramide 0.025-0.028g, tremella extract 0.30-0.34g; Efficacy activation ingredients: freeze-dried needle cherry powder 2.10-2.22g, freeze-dried lemon powder 0.40-0.46g; Compliance additives: erythritol 1.80-1.90g, steviol glycoside 0.0018-0.0022g, freeze-dried mango powder 0.24-0.26g, freeze-dried pineapple powder 0.028-0.032g, citric acid 0.050-0.056g, sodium citrate 0.020-0.022g, natural VE 0.080-0.090g, rosemary extract 0.020-0.022g, colloidal silicon dioxide 0.045-0.048g, ascorbyl palmitate 0.009-0.011g.

2. The oral beverage having skin lightening and moisturizing effects according to claim 1, wherein, The glutathione precursor combination is obtained by mixing L-cysteine and N-acetyl cysteine at a weight ratio of 1:

1.

3. A method of compounding the oral beverage having skin lightening and moisturizing effects according to claim 1, characterized in that, The following steps are included: S1, raw material processing The raw materials are crushed; S2, step-by-step mixing First step: place the 6 ingredients in the core skin color lightening ingredients in the double-cone mixer and mix to ensure uniform dispersion of the ingredients, forming mixture A; Second step: add the 5 ingredients in the darkness improvement ingredients to mixture A and mix to form mixture B; Third step: add the 4 ingredients in the basic moisturizing ingredients to mixture B and mix to form mixture C; Fourth step: add the 2 ingredients in the efficacy activation ingredients and 10 compliance additives to mixture C and mix to obtain the mixed material; S3, granulation Use a dry granulator to granulate the mixed material, set the roller pressure to 5-8 MPa; S4, drying Place the granulated particles in a vacuum drying oven for drying; S5, screening Screen the dried particles through an 80-mesh screen to remove large particle impurities and obtain the finished material; S6, packaging Seal and package the finished material in a sterile environment to obtain the oral solid beverage.

4. A method of compounding the oral beverage having skin lightening and moisturizing effects according to claim 1, characterized in that, The following steps are included: S1, raw material processing The raw materials are crushed; S2, step-by-step mixing First step: place the 6 ingredients in the core skin color lightening ingredients in the double-cone mixer and mix to ensure uniform dispersion of the ingredients, forming mixture A; Second step: add the 5 ingredients in the darkness improvement ingredients to mixture A and mix to form mixture B; Third step: add 4 ingredients in the base moisturizing ingredients to mixture B, mix to form mixture C; Fourth step: add 2 ingredients in the efficacy activating ingredients and 10 compliance additives to mixture C, mix to obtain the mixture material; S3, granulation The mixture material is granulated by a dry granulator, and the roller pressure is set to 5-8 MPa; S4, drying The granules after granulation are dried in a vacuum drying oven; S5, screening The dried granules are screened through an 80-mesh screen to remove large particle impurities to obtain the finished material; S6, dilution and preparation of liquid The finished material is diluted to 1-5 times, stirred to completely dissolve and mix uniformly, filled and sealed, sterilized by proven high-temperature water bath sterilization method, and prepared into a liquid beverage; S7, packaging The liquid beverage is sealed and packaged in a sterile environment to obtain an oral liquid beverage.

5. The method of claim 3 or 4, wherein, In S1, the freeze-dried medlar powder, freeze-dried cherry powder, freeze-dried lemon powder, freeze-dried mango powder, and freeze-dried pineapple powder are crushed to 100-200 mesh.

6. The method of claim 3 or 4, wherein, In S1, the hydrolyzed fish collagen and colloidal silicon dioxide are screened through an 80-mesh screen to remove clumped particles.

7. The method of claim 3 or 4, wherein, In S2: In the first step, the rotation speed is set to 100-150 r / min, and the mixing time is 10-15 min; In the second step, the rotation speed is maintained at 100-150 r / min, and the mixing time is continued for 10 min; In the third step, the rotation speed is adjusted to 120-160 r / min, and the mixing time is 15 min; In the fourth step, the rotation speed is adjusted to 120-180 r / min, and the mixing time is 20-25 min.

8. The method of claim 3 or 4, wherein, In S3, the particle size of the granules is controlled to be 80-120 mesh.

9. The method of claim 3 or 4, wherein, In S4, the drying is carried out at 45-55°C until the moisture content is ≤3%.

10. The use of the oral beverage with skin lightening and moisturizing efficacy according to claim 1 in the field of oral cosmetic foods.