Traditional Chinese medicine composition for preventing and / or treating coronary heart disease and preparation method and application thereof

By combining traditional Chinese medicine ingredients such as Artemisia capillaris, this treatment aims to address coronary heart disease of the phlegm-blood stasis type by using methods of eliminating dampness, relieving pain, and promoting blood circulation. This approach overcomes the shortcomings of existing treatments in systematically regulating the pathogenesis of atherosclerosis and phlegm-blood stasis, achieving a comprehensive therapeutic effect on coronary heart disease through multiple targets and pathways.

CN121695246BActive Publication Date: 2026-06-09HAIHE LAB OF MODERN CHINESE MEDICINE +2
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HAIHE LAB OF MODERN CHINESE MEDICINE
Filing Date
2026-02-11
Publication Date
2026-06-09

AI Technical Summary

Technical Problem

Current Western medicine treatments for coronary heart disease are insufficient in systematically regulating the overall pathological process of atherosclerosis and reversing plaque formation. Traditional Chinese medicine preparations suffer from slow onset of action, insufficient control of acute symptoms, and low bioavailability. Existing traditional Chinese medicine preparations are scattered in their synergistic intervention on the pathogenesis of phlegm and blood stasis, and lack systematic compatibility.

Method used

A traditional Chinese medicine composition is provided, comprising Artemisia capillaris, Atractylodes lancea, Alisma plantago-aquatica, Curcuma longa, Salvia miltiorrhiza, Curcuma longa, Panax notoginseng powder, Corydalis yanhusuo, Pinellia ternata, Coptis chinensis, Panax ginseng, Citrus reticulata peel, and Glycyrrhiza uralensis. It regulates the spleen and stomach through the treatment of removing dampness, relieving pain, promoting blood circulation, and relieving pain. It is designed for coronary heart disease of the phlegm-blood stasis type. It is prepared by water decoction extraction, concentration, and spray drying to produce an oral or non-oral preparation.

Benefits of technology

It significantly improves myocardial ischemia-reperfusion injury, reduces myocardial infarction area, enhances cardiac function indicators, regulates blood lipids, inhibits atherosclerosis, improves blood rheology, and provides a comprehensive therapeutic effect with multi-target synergy, making it suitable for long-term use.

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Abstract

The present application provides a traditional Chinese medicine composition for treating and / or preventing coronary heart disease, and a preparation method and application thereof. Specifically, the traditional Chinese medicine composition of the present application is prepared from raw materials comprising the following components: 8-13 parts of capillaris, 8-12 parts of atractylodes, 8-12 parts of alisma, 8-14 parts of curcuma, 10-20 parts of salvia, 8-14 parts of curcuma, 1-5 parts of panax notoginseng powder, 5-10 parts of rhizoma corydalis, 8-12 parts of pinellia, 5-10 parts of berberis, 4-10 parts of ginseng, 5-12 parts of dried tangerine or orange peel, and 4-10 parts of licorice. The present application also provides a method for preparing the traditional Chinese medicine composition of the present application and the use of the traditional Chinese medicine composition in preparing a medicine for treating and / or preventing coronary atherosclerotic heart disease. The traditional Chinese medicine composition of the present application can reduce blood viscosity, improve heart function, reduce myocardial infarction area, inhibit the formation of atherosclerotic plaques, regulate blood lipid levels, or reduce the level of myocardial injury markers in serum.
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