Use of the protein ambp in the preparation of a formulation for promoting hair follicle cell activity or for the prevention or treatment of hair loss

By regulating hair follicle cell activity through the protein AMBP, promoting hair follicle cell proliferation and hair growth, the problem of poor efficacy of existing hair loss treatments is solved, and more effective hair growth and thickening effects are achieved.

CN121695257BActive Publication Date: 2026-05-08SOUTHERN MEDICAL UNIVERSITY
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Patent Information

Application Number
CN202610186465.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2026-02-10
Publication Date
2026-05-08
Estimated Expiration
2046-02-10

AI Technical Summary

Technical Problem

Existing hair loss treatments such as hair transplantation and drug therapy have side effects and poor efficacy, and lack effective regulation of hair follicle cell activity, resulting in inconsistent treatment outcomes.

Method used

The protein AMBP regulates the activity of hair follicle papilla cells, hair matrix cells, and outer root sheath cells, promoting their proliferation and scavenging of reactive oxygen species, thus promoting hair follicle cycle transition. It can be applied in topical preparations such as liniments, patches, and injectable formulations.

Benefits of technology

The protein AMBP significantly promotes hair follicle cell proliferation, enhances hair follicle cell vitality, promotes hair growth and thickens hair, addresses the shortcomings of existing treatments, and provides a more effective treatment for hair loss.

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Abstract

The present application belongs to the field of biomedical and cosmetic technology, and particularly relates to the application of protein AMBP in the preparation of a preparation for promoting the activity of hair follicle cells or for preventing and treating alopecia. The present application first discovers that the protein AMBP has the activity of regulating the hair follicle hair papilla cells, hair matrix cells and outer root sheath cells, can promote the proliferation of the hair papilla cells, the hair matrix cells and the outer root sheath cells, and improve the ability of the outer root sheath cells to remove active oxygen; also has the effects of promoting the hair follicle cycle transition, promoting hair growth and hair thickening. Therefore, the protein AMBP can be applied to the preparation of a preparation for treating alopecia.
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