Membrane-mediated THz biological regulation mineral ion water composition and preparation method thereof

Abstract

The invention discloses a membrane-mediated THz biological regulation mineral ion water composition and a preparation method thereof, and relates to the technical field of soft substance dielectric regulation and weak-field THz biophysics, the composition comprises an aqueous phase medium and an ion component, the aqueous phase medium is purified water, deionized water or low-salinity base water, or is directly taken from a predetermined water source; the ion component comprises monovalent cations, divalent cations, monovalent anions and / or polyatomic anions; the mineral ion water composition can form stable terahertz dielectric response under the cooperation of a membrane structure; the method is suitable for engineering application of physiotherapy products and related health regulation and control products. A terahertz regulation and control environment can be constructed without an active terahertz emission device; the method is suitable for engineering application of physiotherapy products and related health regulation and control products; the adjustability of terahertz response can be realized by adjusting ion function parameters and membrane structure parameters.

Description

Technical Field

[0001] This invention relates to the field of soft matter dielectric regulation and weak-field terahertz biophysics, and particularly to a membrane-mediated THz bio-regulated mineral ion water composition and its preparation method. Background Technology

[0002] The terahertz (THz) band typically refers to the electromagnetic wave frequency band between microwaves and infrared, with a corresponding frequency range of approximately 0.1–10 THz. Electromagnetic waves in this band are characterized by being non-ionized and having low energy, while also exhibiting high sensitivity to the dielectric properties of water molecules, hydrogen bond networks, and soft matter systems.

[0003] Publicly available research has shown that water and water systems containing mineral ions exhibit significant dielectric response characteristics in the terahertz frequency band, including variations in dielectric constant, dielectric relaxation behavior, and spectral properties related to hydrogen bond structure. This type of research primarily focuses on fundamental physics, chemistry, or biophysics to explain phenomena such as water molecule dynamics, solution dielectric behavior, or molecular vibrational properties.

[0004] On the other hand, in physiotherapy products, health regulation products, or related engineering applications, existing technologies mostly use ordinary water, saline, gels, or solid filler materials as media, and their mechanisms of action mainly rely on thermal effects, mechanical stimulation, or electrical stimulation. For the dielectric properties of water and ion-containing systems in the terahertz frequency band, no engineering-feasible and stable regulation scheme has yet been developed.

[0005] Meanwhile, existing terahertz-related applications mostly rely on active emission sources or high-power devices, which suffer from problems such as complex device structures, concentrated energy, difficulty in long-term safe use, and unsuitability for integration with flexible physiotherapy products. Therefore, the relevant research results have not yet been effectively transformed into technical solutions that can be integrated with daily physiotherapy or health products.

[0006] Furthermore, although some studies have indicated that water and ion-containing systems possess certain response characteristics in the terahertz frequency band, the existing technology still has the following shortcomings: There is no engineered solution to achieve controllability of terahertz response by adjusting the dielectric properties of the ion-water system. Membrane structures have not yet been introduced as frequency-selective interfaces into the regulation pathway of ion-water system-terahertz interaction to regulate the terahertz response of ion-water system. There is no known composition or preparation method that can stably construct a terahertz modulation environment under weak field, non-thermal, and non-current conditions.

[0007] In summary, while existing technologies have revealed some physical properties of water and ion-containing systems in the terahertz frequency band at the basic research level, there is still a lack of technical solutions in the field of engineering applications that can stably construct terahertz frequency-selective responses through mineral ion water systems with the cooperation of membrane structures.

[0008] Therefore, it is necessary to propose a new mineral ion water composition and its preparation method, so that it can form a tunable and controllable terahertz dielectric response under the action of membrane structure, thereby providing basic media support for physiotherapy or health applications related to membrane-mediated terahertz bio-regulation. Summary of the Invention

[0009] This invention provides a membrane-mediated THz bio-regulation mineral ion water composition and its preparation method. With the aid of a membrane structure, a stable and tunable terahertz dielectric response can be formed, enabling its application in physiotherapy or health applications related to membrane-mediated terahertz bio-regulation. It is suitable for physiotherapy products, health regulation products, and related physical regulation media. By filling the physiotherapy product with mineral ions and water, the real part ε′, imaginary part ε″, and dielectric relaxation time τ of the aqueous system are adjusted, making it easier to resonate with THz waves of specific frequencies.

[0010] A membrane-mediated THz bio-regulated mineral ion water composition is provided, the composition comprising: an aqueous phase medium and an ion component: The aqueous medium is purified water, deionized water, or low-mineralized basic water, which can be directly taken from the predetermined water source. Ionic components include: monovalent cations, divalent cations, monovalent anions and / or polyatomic anions; Among them, the monovalent cation is selected from one or more alkali metal ions, and is selected from Na + K + Li + 、Rb + Cs + One or more of the following; The divalent cation is selected from one or more alkaline earth metal ions and / or transition metal ions, and is selected from Ca 2+ Mg 2+ 、Sr 2+ Zn 2+ One or more of the following; Monovalent anions are selected from one or more of halide anions and / or oxygen-containing inorganic anions, and are selected from Cl... - NO3 - One or more of the following; The polyatomic anion is selected from one or more of carbonate, sulfate, and / or organic carboxylate groups, and is selected from HCO3-. - CO3 2-SO4 2- One or more of citrate.

[0011] The aforementioned ions are used to adjust the dielectric relaxation characteristics and dielectric constant distribution of the aqueous system in the 0.1–10 THz frequency band.

[0012] The application of a mineral ionized water composition, wherein the mineral ionized water composition is used in conjunction with a membrane structure in a physiotherapy product, the membrane structure having one or more of the following characteristics: The membrane structure is selected from one or more of the following: TPU, TPX, PTFE, composite membrane, multilayer membrane, and quartz sheet; The thickness of the membrane structure is in the range of 0.1 mm to 2.0 mm.

[0013] Preferably, the thickness of the membrane structure is in the range of 0.05 mm–1.0 mm.

[0014] Preferably, the thickness of the membrane structure is in the range of 0.01 mm–0.5 mm.

[0015] Preferably, the membrane structure has one or more of the following features: It possesses flexibility or adaptability; It has limited permeability to water vapor; It has predictable refractive index and dielectric properties in the terahertz frequency band; It can form a terahertz frequency-selective window under the action of an ion-water system; The membrane structure and the mineral ion water composition form a matched frequency-selective response in the terahertz band.

[0016] A method for preparing a membrane-mediated THz bio-regulated mineral ion water composition, the method being used to prepare the mineral ion water composition of claim 1, the method comprising: Step S1: Provide an aqueous medium: The aqueous medium is taken directly from a predetermined water source or selected from one or more of purified water, deionized water, and low-mineralized base water; Step S2: Add ionic components and dissolve them completely: Add ionic components to the aqueous medium in a predetermined order to fully dissolve each ionic component in the aqueous medium to form a mineral ion water system; The ionic components include one or more of monovalent cations, divalent cations, monovalent anions and / or polyatomic anions; The order, proportion, and concentration of additions are set according to the required dielectric control function; Step S3: Sterilization treatment: According to product application requirements, the obtained mineral ion water composition is sterilized. The sterilization process is selected from one or a combination of the following methods: ultraviolet sterilization, high temperature sterilization, and chemical sterilization; Step S4: Filling: Under controlled conditions, the mineral ion water composition is filled into an encapsulation container that is compatible with the membrane structure; the controlled conditions include one or a combination of the following: vacuum conditions, semi-vacuum conditions, controlled temperature conditions, and light-protected conditions; Step S5: Sealing The filling container is sealed to form a closed or semi-closed system between the mineral ion water composition and the membrane structure. The sealing method includes heat sealing, pressure sealing, or other sealing methods suitable for membrane materials; Step S6: Finished product formation: The mineral ion water composition obtained through the above steps, together with the membrane structure, constitutes a dielectric regulation system for membrane-mediated terahertz biological regulation.

[0017] Compared with the prior art, the beneficial effects of the present invention are: The mineral ion water composition can form a stable terahertz dielectric response under the coordination of the membrane structure. A terahertz control environment can be constructed without an active terahertz emission device; It belongs to a non-thermal, non-electric, and non-invasive physical control system; Suitable for engineering applications in physiotherapy products and related health regulation products; The terahertz response can be tuned by adjusting the ion function parameters and membrane structure parameters. Attached Figure Description

[0018] Figure 1 A schematic diagram of an ion-water-membrane structure according to an embodiment of the present disclosure is shown.

[0019] Figure 2 A schematic diagram of a terahertz frequency selectivity window according to an embodiment of the present disclosure is shown.

[0020] Figure 3 A flowchart illustrating a method for preparing a physiotherapy product containing a mineral ionized water composition according to an embodiment of the present disclosure is shown.

[0021] Figure 4 The diagram shows a terahertz time-domain spectrum obtained from a test of a physiotherapy kit according to an embodiment of this disclosure. Detailed Implementation

[0022] Various exemplary embodiments, features, and aspects of this disclosure will now be described in detail with reference to the accompanying drawings. The same reference numerals in the drawings denote elements that have the same or similar functions. Although various aspects of the embodiments are shown in the drawings, they are not necessarily drawn to scale unless specifically indicated otherwise.

[0023] The term “exemplary” as used herein means “serving as an example, embodiment, or illustration.” Any embodiment illustrated herein as “exemplary” is not necessarily to be construed as superior to or better than other embodiments.

[0024] Furthermore, to better illustrate this disclosure, numerous specific details are set forth in the following detailed description. Those skilled in the art will understand that this disclosure can be practiced without certain specific details. In some instances, methods, means, components, and circuits well known to those skilled in the art have not been described in detail in order to highlight the main points of this disclosure.

[0025] Explanation of the principle (non-limiting literature citation): Public research has shown that water and water systems containing mineral ions have significant dielectric response characteristics in the terahertz band, and their dielectric constant and relaxation behavior are closely related to the hydrogen bond network of water molecules and the ion hydration structure.

[0026] Related studies indicate that different ion types and their concentrations affect the dielectric constant distribution and dielectric relaxation time of aqueous systems in the terahertz band, thereby altering the interaction characteristics between terahertz electromagnetic waves and aqueous systems (see studies on the response behavior of water and ions in the terahertz band in PNAS, eLife, Advanced Science, and other published literature).

[0027] The mineral ion water composition described in this embodiment is based on the above-mentioned physical laws, and the ion-water system is functionally adjusted through engineering methods, forming a dielectric environment that can be used for terahertz control under the constraint of membrane structure.

[0028] This embodiment provides a mineral ion water composition for membrane-mediated terahertz bioregulation. This composition is an exemplary embodiment and does not constitute a limitation on the scope of protection of this invention.

[0029] Aqueous phase medium: In this embodiment, the aqueous phase medium of the mineral ion water composition can be directly taken from a predetermined water source or a mixed aqueous phase of deionized water and low-mineralization base water, wherein the aqueous phase medium serves as the basic carrier for ion dissolution and dielectric regulation.

[0030] Ionic components: In this embodiment, the ionic components include a portion of the following ionic systems: Monovalent cations: selected from a + K + Li + 、Rb + Cs + One or more of the following; Divalent cations: selected from Ca 2+ Mg 2+ 、Sr2+ Zn 2+ One or more of the following; Monovalent anions: selected from Cl - NO3 - One or more of the following; Polyatomic anions: selected from HCO3 - CO3 2- SO4 2- One or more of them.

[0031] In this embodiment, the total ionic strength of the ionic components is controlled within a predetermined range, which is 5 mmol / L–80 mmol / L, and the ratio between each ion is an approximate ratio or a functional ratio.

[0032] The molar ratio of divalent cations to monovalent cations is within the range of 0.05–0.30. This embodiment only lists some representative ions as examples; other optional ions can be adjusted according to actual application requirements, but this does not constitute a limitation of the invention.

[0033] This invention provides a mineral ion water composition that, by adjusting the dielectric properties of the ion-water system, achieves a terahertz frequency-selective response in conjunction with a membrane structure. A method for preparing this mineral ion water composition is provided to ensure its compositional stability, dielectric consistency, and engineering feasibility. This constructs a non-thermal, non-current, and non-invasive terahertz bio-regulation medium that requires no active terahertz emission source.

[0034] By functionally modulating the dielectric properties of the ion-water system and forming a terahertz frequency-selective response under the constraint of the membrane structure, a stable and tunable terahertz dielectric control environment is constructed.

[0035] Ion functional characteristics (core mechanism description): In this embodiment, through the combination of the above-mentioned ionic components, the mineral ion water composition possesses one or more of the following functional characteristics in the terahertz frequency band: Adjusting the real part ε′ of the dielectric constant of the aqueous system to enhance the storage and polarization capability of terahertz electromagnetic energy in the aqueous system; The imaginary part ε″ of the dielectric constant of the aqueous system is adjusted to control the dissipation rate of terahertz electromagnetic energy. By adjusting the dielectric relaxation time τ of the aqueous system to match the physical parameters of the membrane structure, a frequency-selective response can be formed in the 0.1–10 THz frequency band.

[0036] Through the above functional adjustments, the mineral ion water composition can synergistically construct a stable terahertz dielectric modulation environment with the membrane structure under weak field conditions.

[0037] Membrane structures used in conjunction with: In this embodiment, the mineral ion water composition, prepared according to the aforementioned method, is used in conjunction with a flexible membrane structure. The membrane structure is selected from one or a combination of the following: a TPU membrane, a TPX membrane, a composite membrane, or a multilayer membrane structure. The thickness of the membrane structure is in the range of 0.01 mm–2.0 mm (determined according to the membrane structure). This is to ensure that the membrane structure and the mineral ion water composition form a matching frequency selectivity window in the terahertz frequency band.

[0038] As shown in Figure 1, the membrane-mediated terahertz biological regulation system of the present invention includes the following structural units: (1) Mineral ion water composition The mineral ion water composition is an artificially prepared ion-water system, which includes a network of water molecules and ion components distributed within it.

[0039] The ionic components are functionally configured to adjust the real part ε′, the imaginary part ε″, and the dielectric relaxation time τ of the aqueous system.

[0040] (2) Membrane structure The membrane structure is disposed on the outside of the mineral ion water composition to isolate the mineral ion water composition from the external environment.

[0041] The membrane structure exhibits predictable dielectric properties in the terahertz band and participates in the terahertz modulation process as a frequency-selective interface.

[0042] (3) Liquid-film interface A liquid-membrane interface is formed between the mineral ion water composition and the membrane structure. This interface is the main region where terahertz electromagnetic energy couples with the ion-water system.

[0043] (4) Terahertz action path Terahertz electromagnetic energy originating from the external environment or the weak field conditions of the human body. After the membrane structure is modulated, it acts on the interior of the mineral ion water composition through the liquid-membrane interface. A frequency-selective response is formed by the dielectric properties of the ion-water system.

[0044] like Figure 2 As shown, the mineral ion water composition of the present invention, with the cooperation of the membrane structure, forms a frequency-selective response window in the terahertz band.

[0045] The horizontal axis in the figure represents the terahertz frequency range, and the vertical axis represents the terahertz electromagnetic response intensity.

[0046] Under the combined effect of the dielectric properties of the ion-water system and the physical parameters of the membrane structure, a response enhancement region is formed within a predetermined terahertz frequency band, namely the terahertz frequency selectivity window.

[0047] The terahertz frequency selectivity window is determined by the following factors: The real part ε′ of the dielectric constant of the mineral ion water composition; The imaginary part ε″ of the dielectric constant of a mineral ionized water composition; Dielectric relaxation time τ of mineral ionized water composition; The thickness, refractive index, and dielectric properties of the membrane structure.

[0048] Within the frequency selectivity window, terahertz electromagnetic energy is effectively coupled with the mineral ion water composition; Outside the window, the terahertz response is significantly reduced.

[0049] The specific location and width of the frequency selectivity window can be adjusted according to the configuration of the ion-water system and the membrane structure. However, the invention is not limited to specific frequency values.

[0050] As shown in Figure 3, the preparation process of the mineral ion water composition of the present invention includes the following steps: Provide an aqueous phase medium: Provide an aqueous phase medium as a basic carrier, wherein the aqueous phase medium can be directly taken from a predetermined water source or purified water or deionized water, and can be directly taken from a predetermined water source.

[0051] One or more combinations of low-mineralized base water are used to construct mineral ion water compositions.

[0052] Aqueous phase condition control (optional): According to application requirements, the aqueous medium is subjected to engineered condition control treatment to make it suitable for the subsequent construction of membrane-mediated terahertz modulation environment.

[0053] The condition control process includes one or more of the following conditions: temperature control, light avoidance control, ambient gas control, or static equilibration treatment.

[0054] Filling: Under controlled conditions, the aqueous medium is filled into an encapsulation container that is compatible with the membrane structure.

[0055] Sealing process: The packaging container is sealed to form a closed or semi-closed system between the mineral ion water composition and the membrane structure, resulting in a finished ion-water-membrane regulation system for membrane-mediated terahertz biological regulation.

[0056] Application scenario description: The mineral ion water composition and its membrane complex system can be applied to: physiotherapy bags, physiotherapy pads; waterbeds; wearable physiotherapy products; and other devices that require the construction of a terahertz dielectric-controlled environment.

[0057] The test report clearly states the results for the mineral ion water composition and its membrane complex. This product can be tested for THz reflection peaks and a clear reflection peak can be measured.

[0058] like Figure 4 As shown in the test results, the sample has obvious reflection peaks at 0.5THz and 0.8THz.

[0059] The various embodiments of this disclosure have been described above. These descriptions are exemplary and not exhaustive, nor are they limited to the disclosed embodiments. Many modifications and variations will be apparent to those skilled in the art without departing from the scope and spirit of the described embodiments. The terminology used herein is chosen to best explain the principles, practical application, or technical improvements to the embodiments in the market, or to enable others skilled in the art to understand the embodiments disclosed herein.

Claims

1. A membrane-mediated THz bio-regulated mineral ion water composition, characterized in that, The composition comprises: an aqueous medium and an ionic component. The aqueous medium is: purified water, deionized water, or low-mineralized base water, or directly taken from a predetermined water source; Ionic components include: monovalent cations, divalent cations, monovalent anions and / or polyatomic anions; Among them, the monovalent cation is selected from one or more alkali metal ions, and is selected from Na + K + Li + 、Rb + Cs + One or more of the following; The divalent cation is selected from one or more alkaline earth metal ions and / or transition metal ions, and is selected from Ca 2+ Mg 2+ 、Sr 2+ Zn 2+ One or more of the following; Monovalent anions are selected from one or more of halide anions and / or oxygen-containing inorganic anions, and are selected from Cl... - NO3 - One or more of the following; The polyatomic anion is selected from one or more of carbonate, sulfate, and / or organic carboxylate groups, and is selected from HCO3-. - CO3 2- SO4 2- One or more of citrate.

2. The application of the mineral ion water composition, characterized in that, The mineral ionized water composition is used in conjunction with a membrane structure in therapeutic products, the membrane structure having one or more of the following characteristics: The membrane structure is selected from one or more of the following: TPU, TPX, PTFE, composite membrane, multilayer membrane, and quartz sheet; The thickness of the membrane structure is in the range of 0.01–2.0 mm.

3. The application of the mineral ion water composition according to claim 2, characterized in that, The thickness of the membrane structure ranges from 0.05 mm to 1.0 mm.

4. The application of the mineral ion water composition according to claim 2, characterized in that, The thickness of the membrane structure is in the range of 0.01 mm–0.5 mm.

5. The application of the mineral ion water composition according to claim 2, characterized in that, The membrane structure has one or more of the following characteristics: It possesses flexibility or adaptability; It has limited permeability to water vapor; It has predictable refractive index and dielectric properties in the terahertz frequency band; It can form a terahertz frequency-selective window under the action of an ion-water system; The membrane structure and the mineral ion water composition form a matched frequency-selective response in the terahertz band.

6. A method for preparing a membrane-mediated THz bio-regulated mineral ion water composition, characterized in that, The method includes: Step S1: Provide an aqueous medium: The aqueous medium is taken directly from a predetermined water source or selected from one or more of purified water, deionized water, and low-mineralized base water; Step S2: Add ionic components and dissolve them completely: Add ionic components to the aqueous medium in a predetermined order to fully dissolve each ionic component in the aqueous medium to form a mineral ion water system; The ionic components include one or more of monovalent cations, divalent cations, monovalent anions and / or polyatomic anions; The order, proportion, and concentration of additions are set according to the required dielectric control function; Step S3: Sterilization treatment: According to product application requirements, the obtained mineral ion water composition is sterilized. The sterilization process is selected from one or a combination of the following methods: ultraviolet sterilization, high temperature sterilization, and chemical sterilization; Step S4: Filling: Under controlled conditions, the mineral ion water composition is filled into an encapsulation container that is compatible with the membrane structure; the controlled conditions include one or a combination of the following: vacuum conditions, semi-vacuum conditions, controlled temperature conditions, and light-protected conditions; Step S5: Sealing The filling container is sealed to form a closed or semi-closed system between the mineral ion water composition and the membrane structure. The sealing method includes heat sealing, pressure sealing, or other sealing methods suitable for membrane materials; Step S6: Finished product formation: The mineral ion water composition obtained through the above steps, together with the membrane structure, constitutes a dielectric regulation system for membrane-mediated terahertz biological regulation.

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