Inner supporting device

Abstract

The invention relates to experimental equipment, in particular to an inner support device for a long-acting preparation in-vitro release evaluation method, which can be arranged in a container and comprises a main body, an inner support and an outer support, the hanging part is connected with the main body and is used for being hung on the wall surface of the container; the mounting assembly comprises a mounting part which is connected with the main body and is used for mounting a sample; and the two ends of the connecting part are connected with the mounting part and the main body correspondingly, and the connecting part can be used for adjusting the distance between the main body and the mounting part. The inner supporting device can adapt to and be arranged in the container through the hanging part, and the distance between the mounting part and the main body can be adjusted through the connecting part, so that a sample can be arranged at a specified height in a medium in the container, and the in-vitro release evaluation requirements of different dosage forms of a long-acting preparation are met.

Description

Technical Field

[0001] This patent relates to the field of experimental equipment technology, and in particular to an internal support device. Background Technology

[0002] With the continuous development of medical technology, the demand for treatment of chronic diseases is increasing. Many chronic diseases require long-term medication, and ordinary short-acting drugs often fail to effectively control the condition due to missed doses, and frequent medication also leads to poor patient adherence. In contrast, long-acting formulations achieve sustained and slow release of the drug after a single dose by controlling drug release, reducing the frequency of dosing from multiple daily doses to once every few weeks, months, or even years. This significantly reduces the frequency of dosing and maintains the drug concentration at the optimal therapeutic level for a long time, avoiding both the reduction in efficacy due to falling below the minimum therapeutic concentration and the safety issues caused by exceeding the threshold concentration, thus significantly improving the convenience and adherence of patients.

[0003] Therefore, developing novel long-acting formulations that can achieve single-dose administration and sustained drug release is of great significance for improving treatment efficacy and patients' quality of life.

[0004] In the development and quality monitoring of long-acting formulations, in vitro release assays are crucial for ensuring the safety and efficacy of these formulations. They can simulate the in vivo drug release process to a certain extent, predict in vivo release behavior, thereby reducing the number of in vivo tests. This helps researchers understand the drug release behavior of formulations in a simulated in vivo environment, providing important information for formulation research and evaluation, and accelerating the product development process. Simultaneously, it is one of the most important methods for controlling the quality of long-acting formulations.

[0005] Long-acting formulations come in various types, including microspheres, in-situ gels, implants, vaginal rings, and intrauterine devices. Furthermore, because each formulation / specification contains different active pharmaceutical ingredients, dosages, and release cycles, current pharmacopoeias and regulatory guidelines in various countries do not provide clear guidance on the release methods of long-acting formulations.

[0006] The shaker method is currently the most widely used method for in vitro release testing of long-acting formulations. It involves placing the formulation in a sealed container containing a dissolution medium at a constant temperature, and periodically sampling and measuring the results over a specified time period to assess the drug release process in vivo. Compared to methods with fixed dissolution devices, such as flow-through cell, paddle / basket, and reciprocating cylinder methods, it is easier to select containers of different shapes and sizes and set different volumes of release medium according to the different properties of long-acting formulations, making it simple and easy to implement.

[0007] As mentioned earlier, these long-acting formulations are diverse. Therefore, when using the shaker method for experiments, some low-density long-acting formulations may experience sample loss because they float on the medium; while the position of some formulations in the medium may change over time during the in vitro release study. The instability of the formulation's position in the medium may also be affected by different hydrodynamics, thus affecting the accuracy and reproducibility of the release results. Summary of the Invention

[0008] To solve, or at least partially solve, the aforementioned technical problems, this patent provides an internal support device that can be installed inside a container, comprising:

[0009] main body;

[0010] The mounting component connects to the main body and is used to attach to the wall of the container;

[0011] The installation components include:

[0012] Mounting components, connected to the main body, are used to mount samples;

[0013] The connecting component connects the mounting component and the main body at both ends, and can be used to adjust the distance between the main body and the mounting component.

[0014] Optionally, in the internal support device as described above, the connecting component includes:

[0015] The telescopic component has its end furthest from the main body connected to the mounting component. The telescopic component can change its length under external force to change the height of the sample mounted on the mounting component inside the container.

[0016] Alternatively, in the internal support device as described above, the telescopic component is a metal wire twisted into a spiral shape.

[0017] Optionally, in the internal support device as described above, the connecting component further includes:

[0018] The adjusting component, which is connected to the main body, is used to adjust the length of the telescopic component.

[0019] Optionally, in the internal support device as described above, the mounting components include:

[0020] The mounting section is used to mount samples;

[0021] The mounting part is suspended from the connecting component via the lifting part.

[0022] Optionally, in the internal support device as described above, the mounting part is a clamp, and the lifting part includes at least two clamping rods, the end of each clamping rod being connected to the clamp, and the mounting components further include:

[0023] The tightening sleeve holds the various clamping rods of the lifting section together.

[0024] Each clamping rod of the lifting part opens on the side away from the main body and can be clamped by the constraint generated when the tightening sleeve moves towards the opening side.

[0025] Optionally, in the internal support device as described above, the main body further includes:

[0026] The elastic component connects the main body and the hanging component, causing the hanging component to move away from the main body and enabling the main body to be supported on the inner wall of the container through the hanging component.

[0027] Optionally, in the internal support device as described above, the elastic component is a spiral metal wire, which supports the inner wall of the container through its own elastic force.

[0028] Optionally, in the internal support device as described above, the mounting component includes:

[0029] The abutment joint can be attracted by magnetic force;

[0030] A spring, with its two ends connected to the abutment and the main body, respectively;

[0031] Furthermore, the main body includes:

[0032] The frame has a receiving slot and a central slot;

[0033] An electromagnet is installed in the central slot.

[0034] When energized, the electromagnet generates a magnetic force to attract the hanging parts to the frame and house the spring in the receiving groove.

[0035] Optionally, in the internal support device as described above, the elastic component is a spring, and at least three springs are arranged as a group to connect the hanging component and the main body.

[0036] Optionally, in the internal support device as described above, the outer wall of the hanging component away from the main body is an arc surface, and at least three hanging components are evenly distributed around the wall surface of the main body.

[0037] Compared to existing documents, this patent has the following technical advantages:

[0038] The connecting component can adjust the position of the sample mounted on the mounting component relative to the main body, thereby adjusting the height of the sample in the medium within the container and controlling the influence of the sample depth in the medium on the sample dissolution rate. The clamping component can provide a continuous clamping force to hold the sample continuously dissolving in the medium, allowing the sample to be stably held in its original position. The hanging component can be hung on the inner wall of the container, which can stably hold the main body inside the container and can adapt to containers of various sizes and models, making the application scenarios more extensive. The mounting component can be replaced with different styles to suit different types of samples. Attached Figure Description

[0039] To more clearly illustrate the embodiments of this patent, the relevant drawings will be briefly described below. It should be understood that the drawings described below are only for illustrating some embodiments of this patent, and those skilled in the art can obtain many other technical features and connections not mentioned herein based on these drawings.

[0040] Figure 1 This is a three-dimensional schematic diagram of an internal support device according to an embodiment of this patent;

[0041] Figure 2 This is a cross-sectional schematic diagram of an internal support device according to an embodiment of this patent;

[0042] Figure 3 This is an exploded schematic diagram of an internal support device according to an embodiment of this patent;

[0043] Figure 4 This is a three-dimensional schematic diagram of an installation component according to an embodiment of this patent;

[0044] Figure 5 This is a three-dimensional schematic diagram of an internal support device with a spiral metal wire according to an embodiment of this patent.

[0045] Figure 6 This is a partial schematic diagram of an internal support device according to an embodiment of this patent;

[0046] Figure 7 This is a three-dimensional schematic diagram of an internal support device with a wire mesh cage according to an embodiment of this patent.

[0047] Figure 8 This is a three-dimensional schematic diagram of a T-shaped ring mounting component according to an embodiment of this patent;

[0048] Figure 9 This is a three-dimensional schematic diagram of another T-ring mounting component according to an embodiment of this patent;

[0049] Figure 10 This is a schematic diagram of the fit between the T-shaped protrusion and the T-shaped groove in an embodiment of this patent.

[0050] Explanation of reference numerals in the attached figures:

[0051] A. Internal support device;

[0052] 1. Main body;

[0053] 11. Elastic component; 12. Frame; 121. Receiving groove; 122. Central groove; 13. Electromagnet; 14. Receiving hole; 141. Guide structure;

[0054] 2. Mounting components;

[0055] 21. Connecting joint; 22. Spring;

[0056] 3. Install components;

[0057] 31. Installation component; 311. Installation part; 3112. Clamp; 3113. Net cage; 312. Lifting part; 3121. Clamping rod; 3122. T-shaped protrusion; 313. Tightening sleeve;

[0058] 32. Connecting component; 321. Telescopic component; 3211. Guide groove; 322. Adjusting component; 3221. Adjusting sleeve; 3222. Sleeve; 3223. Through hole; 323. T-slot;

[0059] 4. T-ring. Detailed Implementation

[0060] The patent will now be described in detail with reference to the accompanying drawings.

[0061] Implementation Method 1

[0062] The inventors of this application have discovered that fixing a long-acting formulation in a suitable position within a medium can improve the accuracy and reproducibility of release results.

[0063] In view of this, the first embodiment of this patent discloses an internal support device A, see [link to patent]. Figure 1 As shown, the internal support device A is installed inside the container and includes:

[0064] Entity 1;

[0065] Hanging component 2 is connected to the main body 1 and is used to hang on the wall of the container;

[0066] Install component 3, including:

[0067] Mounting component 31 is connected to the main body 1 and is used to mount the sample;

[0068] The connecting component 32 is connected to the mounting component 31 and the main body 1 at both ends, and the connecting component 32 can be used to adjust the distance between the main body 1 and the mounting component 31.

[0069] The main body 1 is located within the space of the container that does not contain the medium. When the container contains the medium, the main body 1 does not come into contact with the medium. The hanging component 2 can be hung on the inner wall of the container or at the container opening to place the main body 1, which is connected to the hanging component 2, inside the container. The mounting assembly 3 includes a mounting component 31 and a connecting component 32. The connecting component 32 is used to directly connect to the main body 1 for mounting the sample. The two ends of the connecting component 32 are respectively connected to the mounting component 31 and the main body 1. The relative position between the connecting component 32 and the main body 1 can be adjusted by changing its own length or by moving relative to the main body 1, thereby adjusting the position of the sample mounted on the mounting component 31 in the medium contained in the container.

[0070] The internal support device A configured as described above achieves the following technical effects:

[0071] 1. The connecting component 32 can adjust the position of the sample mounted on the mounting component 31 relative to the main body 1, thereby adjusting the height of the sample in the medium within the container and controlling the depth of the sample in the medium. By calibrating the depth, the correlation between the sample depth and the dissolution rate can be clearly defined.

[0072] 2. The clamping component can provide a continuous clamping force for the mounting part 311 to clamp the sample that is constantly dissolving in the medium, so that the sample can be stably kept in its original position.

[0073] 3. The hanging component 2 can be hung on the inner wall of the container, which can stably keep the main body 1 inside the container and can adapt to containers of various sizes and models, making the application scenarios of the internal support device A more extensive.

[0074] It is worth mentioning that the form in which the hanging component 2 is attached to the container wall can be varied. Depending on the shape of the container, in some cases, the hanging component 2 can be attached to the opening of the container through an end hook structure, or it can be attached to the container wall through cooperation with components set on the container wall. In other cases, when the container needs to be closed, an elastic structure can be set between the main body 1 and the hanging component 2 to give the hanging component 2 elastic potential energy, causing the hanging component 2 to tend to move away from the main body 1 and abut against the inner wall of the container. By having the hanging component 2 abut against the inner wall of the container, the main body 1 can be placed inside the container with a closed opening, and the structural requirements of the container itself are not high, making it more widely applicable.

[0075] It should be noted that in some specific scenarios, when testing samples of long-acting contraceptive preparations, the container contains a medium to mimic the uterine environment. Long-acting preparations achieve sustained, slow release of the drug after a single dose by controlling drug release; the dosing period can last for weeks, months, or even years after a single dose. Therefore, when initially conducting observational experiments, it is necessary to select a suitable type of mounting component 3 to accommodate the sample.

[0076] Accordingly, depending on the differences in the installed samples, various different types of mounting components 3 can be replaced. The mounting component 3 is mounted on the main body 1 via its connecting part 32, and the connection structure between the main body 1 and the connecting part 32 can be configured as a detachable structure to replace different types of mounting components 3.

[0077] Optionally, the outer wall of the inner support device A, away from the main body 1, is curved, and at least three hanging parts 2 are evenly distributed around the wall of the main body 1. Specifically, the main body 1 can be cylindrical, and multiple hanging parts 2 can be arranged in a surrounding manner on the side of the cylindrical main body 1. For example, when there are three hanging parts 2, they can be evenly arranged around the side of the main body 1 at 120-degree intervals; when there are six hanging parts 2, they can be evenly arranged around the side of the main body 1 at 60-degree intervals, and so on. By arranging multiple hanging parts 2 at equal angles, after the hanging parts 2 come into contact with the container, the main body 1 connected to the hanging parts 2 can be more stably positioned in the space inside the container.

[0078] Implementation Method 2

[0079] This embodiment discloses an internal support device A. This embodiment further improves upon the first embodiment by adding a telescopic component 321 and an adjusting component 322, allowing the adjusting component 322 to adjust the height of the telescopic component 321. Specifically, see [link to documentation]. Figure 1 and Figure 2 As shown, the connecting component 32 of the inner support device A further includes:

[0080] The telescopic component 321 has one end away from the main body 1 connected to the mounting component 31. The telescopic component 321 can change its length under the action of external force to change the height of the sample mounted on the mounting component 31 inside the container.

[0081] The telescopic component 321 can be set on the main body 1 near the medium inside the container. The telescopic component 321 can be adjusted relative to the main body 1. Specifically, the telescopic component 321 can move linearly relative to the main body 1, or the telescopic component 321 can change its own length to adjust the height position of its end mounting component 31 relative to the main body 1, thereby adjusting the height position of the sample in the medium inside the container.

[0082] The telescopic component 321 allows for better adjustment of the sample's height within the container, enabling the sample to release the reagent at a preset height above the liquid surface of the medium. This reduces the impact of sample position changes and fluid factors at different heights on the accuracy of the release results, thereby improving reproducibility.

[0083] In some embodiments, the telescopic member 321 can move linearly relative to the body 1 to adjust the position of the mounting member 31 relative to the body 1. For example, the telescopic member 321 can be an adjusting rod and can move linearly relative to the body 1 under the adjustment of external force to change the distance between the mounting member 31 and the body 1, thereby adjusting the depth of the sample in the medium.

[0084] See Figure 5 As shown, the telescopic component 321 of the inner support device A can also be a metal wire twisted into a spiral shape. That is, the telescopic component 321 can be a flexible, spiral-shaped metal wire. The wire changes its length under external force to change the height of the mounting component 31 relative to the main body 1, thereby changing the height of the sample in the medium. Furthermore, the wire can be used in conjunction with a fixing rod to fix the end of the wire at a specific height, thereby adjusting the height of the sample in the medium. The spiral-shaped metal wire is easy to lengthen, and the wire as the telescopic component 321 has the advantages of simple structure and convenient assembly and disassembly.

[0085] Alternatively, in some other embodiments, see [link to other embodiments]. Figure 3 As shown, the connecting component 32 of the inner support device A further includes:

[0086] Adjustment component 322 and telescopic component 321 are connected to the main body 1 through adjustment component 322 and are used to adjust the length of telescopic component 321.

[0087] The adjusting component 322 can be disposed on the main body 1 and connected to the main body 1 and the telescopic component 321. The position of the telescopic component 321 relative to the main body 1 can be changed by applying an external force to the adjusting component 322.

[0088] Specifically, the adjusting component 322 can be a deformable material, for example, a coated metal sheet that does not react with the medium or sample. By changing the shape of the metal sheet, the position of the mounting component 31 relative to the main body 1 is changed, so that the sample mounted on the mounting component 31 is positioned at a suitable height in the medium. The deformable material allows for simple and quick adjustment of the position between the mounting component 31 and the main body 1, and has strong applicability to different containers.

[0089] Unlike changing its own length, in some other embodiments, the distance between the telescopic component 321 and the main body 1 can be changed by means of transmission.

[0090] Other structures are provided at the bottom of the hole. The main body 1 is provided with a receiving hole 14, and a guide structure 141 is provided inside the receiving hole 14. A guide groove 3211 that cooperates with it is provided on the telescopic component 321. The guide structure 141 is used to enable the telescopic component 321 to rotate along its own axis. Under the guidance of the guide structure 141, this rotational motion is converted into a linear motion of the telescopic component 321 along the axial direction of the receiving hole 14.

[0091] Specifically, the adjusting component 322 can be nested within the receiving hole 14 of the main body 1. The adjusting component 322 may include an adjusting sleeve 3221 and a connecting portion 3222. The connecting portion 3222 is disposed within the receiving hole 14 of the main body 1, and the adjusting sleeve 3221 is disposed at the end of the connecting portion 3222. The dimension of the adjusting sleeve 3221 perpendicular to the axial direction can be larger than that of the main body 1 it contacts, allowing the adjusting sleeve 3221 to protrude beyond the main body 1, facilitating the application of external force to the adjusting sleeve 3221 and its rotation. A through hole 3223 is provided along the rotation axis of the adjusting component 322, and the through hole 3223 has internal threads. Simultaneously, the telescopic component 321 can be a rod disposed within the adjusting component. This rod has threads along its circumferential surface, which engage with the threads inside the through hole 3223. When the adjusting component 322 rotates, the threads inside the through hole 3223 drive the threads of the engaging telescopic component 321 to rotate, thereby enabling the telescopic component 321 to move linearly along the axial direction of the through hole 3223.

[0092] With the internal support device A configured as described above, the telescopic component 321 can move directly in a straight line to change the distance between the mounting component 31 and the main body 1, thereby adjusting the height of the sample in the medium. The advantage of the screw drive method is that it allows the movement of the telescopic component 321 to be very stable and the distance to be precisely controlled, so that the height of the sample in the medium can be accurately calculated and controlled.

[0093] Implementation Method 3

[0094] This embodiment discloses an internal support device A. This embodiment is a further improvement upon the first embodiment, the improvement being that by adding a mounting part 311 and a lifting part 312, a method for mounting various types of samples is provided. Specifically, see... Figure 3 and Figure 4 As shown, the mounting component 31 of the inner support device A includes:

[0095] Mounting section 311, which is used to mount the sample;

[0096] The lifting part 312 and the mounting part 311 are suspended on the connecting part 32 through the lifting part 312.

[0097] The lifting part 312 is detachably connected to the connecting part, and the mounting part 311 is provided at the end of the lifting part 312, allowing samples to be mounted. The lifting part 312 can be detachably connected to the connecting part 32 via a fitting groove structure or clamping. This detachable connection facilitates the replacement of different models and types of mounting parts 31 for different samples.

[0098] Specifically, see Figure 1 and Figure 2 As shown, when the disassembly and assembly parts are fitted with a groove structure, a T-slot 323 can be opened on the connecting part 32, and a T-shaped protrusion 3122 that matches the T-slot 323 structure can be set on the lifting part 312. The T-shaped protrusion 3122 is sent into the T-slot 323 to form a fit, thereby realizing the replacement of the installation part 31 without affecting the original height of the sample relative to the main body 1, which has the advantage of easy disassembly and assembly.

[0099] It is worth mentioning that the internal support device A can be used to test contraceptive samples, including but not limited to long-acting contraceptive formulations such as O-rings, T-rings, Y-rings, uterine rings, and fancy rings. Figure 8 and Figure 9 As can be seen from the two T-rings 4 in the example, different mounting methods can be used for different types of long-acting formulation samples. When mounting closed rings such as O-rings and cylindrical rings, clamps can be used for holding. When testing long-acting formulation samples with rods such as T-rings, Y-rings, T-rings, or fancy rings, the end of the rod part of the sample can be set as a T-shaped protrusion, which cooperates with the T-slot 323 opened on the connecting part 32, so that the mounting part 31 can be detachably mounted on the connecting part 32, which is convenient for changing different types of samples. Figure 10As shown, the T-shaped protrusion 3122 slides into the opening on one side of the T-slot 323, forming a T-shaped structure fit, allowing the mounting component 31 to be installed on the connecting component 32. When it is necessary to replace the mounting component 31, the T-shaped protrusion 3122 is removed from the T-slot to allow other types of connecting components 32 to be installed.

[0100] Obviously, the contraceptive samples described above are merely one example of the embodiments of this patent. The inner support device A can also be used to test non-contraceptive samples, such as samples of sustained-release drugs used for the treatment of intrauterine diseases.

[0101] Optionally, see Figure 3 and Figure 4 As shown, the mounting part 311 of the inner support device A is a clamp 3112, and the lifting part 312 includes at least two clamping rods 3121, the end of each clamping rod 3121 being connected to the clamp 3112. Furthermore, the mounting component 31 also includes:

[0102] The tightening sleeve 313 holds the various clamping rods 3121 of the lifting part 312 together;

[0103] Each clamping rod 3121 of the lifting part 312 opens on the side away from the main body 1 and can be clamped under the constraint generated when the tightening sleeve 313 moves toward the opening side.

[0104] In this embodiment, at least two clamping rods 3121 can be provided on the lifting part 312. The tightening sleeve 313 sleeves the clamping rods 3121 together. The clamping rods 3121 can be moved along the direction of the clamping rods 3121 to achieve mutual contraction or dispersion, so that the end clamp 3112 can clamp or remove the sample. This arrangement has a good clamping effect for small samples and can provide a continuous clamping force.

[0105] Specifically, when two clamping rods 3121 are provided, the clamping surfaces of the two clamps 3112 are arranged facing each other. The two clamping rods 3121 can gradually open away from the main body 1, and the opening angle between the two clamping rods 3121 can be within 0 to 45 degrees. When the tightening sleeve 313 gradually approaches the sample from the side of the clamping rods 3121 away from the sample, under the tightening action of the tightening sleeve 313, the two clamping rods 3121 gradually close together, causing the end clamps 3112 to approach each other, contact the sample, and clamp the sample. When the tightening sleeve 313 continues to approach the sample, the sample is subjected to a certain pressure, which can fix the sample. It is worth mentioning that the contact surface between the clamps 3112 and the sample can be textured to increase the friction between the clamps 3112 and the sample.

[0106] In some embodiments, the contact method between the chuck 3112 and the sample can be changed according to the shape of the sample to reduce the influence of the chuck 3112 or the clamping action on the sample dissolution rate. For example, when the sample is cylindrical, the paired chucks 3112 can be configured to conform to the curved shape of the side of the cylindrical sample, covering the side of the sample to improve stability.

[0107] In addition, considering that part of the sample is difficult to contact the medium in the container due to the influence of the clamp, multiple holes can be opened on the clamp 3112 so that the medium can pass through the holes and contact the sample, thereby reducing the influence of the clamp 3112 on the dissolution rate of the medium.

[0108] See Figure 7 As shown, considering that some low-density long-acting formulations may float on the medium, there may be sampling losses. Moreover, the density change of the formulation during release in the medium may cause it to disperse into fragments, which may float and be affected by the drug release density at different heights within the medium.

[0109] Therefore, in an optional embodiment, the mounting part 311 can also be configured as a mesh box 3113, with the sample placed inside the mesh box 3113, allowing the medium to fully contact the sample through the mesh openings of the mesh box. This configuration ensures that the vast majority of the sample remains at the height of the mesh box 3113 during release, minimizing the impact of sample fragments floating in the medium.

[0110] In addition, a tray 3114 can be installed on the mesh cage 3113 to catch undissolved samples that fall out of the mesh cage 3113, or insoluble residues that leak out of the mesh of the mesh cage 3113. The tray 3114 can be placed deeper in the medium relative to the mesh cage 3113, and the bottom surface of the tray 3114 can cover the bottom surface of the mesh cage 3113, so that the vertical projection of the mesh cage 3113 can fall completely into the bottom surface of the tray 3114. Setting the tray 3114 can catch the incompletely dissolved samples that leak out of the mesh cage 3113, preventing the samples from sinking to the bottom and thus ensuring the accuracy of the experimental results.

[0111] Implementation Method 4

[0112] This embodiment discloses an internal support device A. This embodiment is a further improvement upon the first embodiment, wherein the improvement lies in the addition of a structure to the main body 1, allowing the main body 1 to be attached to the container via a retractable metal disc. Specifically, see... Figure 5 As shown, the main body 1 of the internal support device A also includes:

[0113] The elastic component 11 connects the main body 1 and the hanging component 2, causing the hanging component 2 to move away from the main body 1 and enabling the main body 1 to be supported on the inner wall of the container through the hanging component 2.

[0114] Optionally, see Figure 5 As shown, the elastic component 11 of the inner support device A is a spiral metal wire. The elastic component 11 uses its own elastic force to support the hanging component 2 on the inner wall of the container.

[0115] In this embodiment, the spiral metal wire extends from the center of the circle in a direction away from the center. Each loop of metal wire has a certain gap with the loop inside it. The gap between two adjacent loops of metal wire can be changed by external force to form a spiral shape with a compressible radius, i.e., forming a metal disc. The outermost loop of the metal disc is connected to the hanging component 2. Its working principle is that the metal disc changes its radius under the influence of external force until it can adapt to the inner diameter of the container wall. Then, it is placed inside the container, and the external force is removed, allowing the hanging component 2 connected to the outermost loop of the metal wire to hang on the container wall, thus placing the main body 1 inside the container. For example, when the radius of the metal disc is smaller than the inner wall of the container in its natural state, an external force can be applied to expand the metal disc, and the main body 1 can be hung inside the container through the hanging component 2. Conversely, when the radius of the metal disc is larger than the inner wall of the container in its natural state, an external force can be applied to reduce the radius of the metal disc, and the main body can be hung inside the container through the hanging component 2.

[0116] The spiral metal wire has a relatively simple structure. The radius of the metal disc can be directly adjusted by hand to be hung inside the container via the hanging part 2. It is easy to use, highly adaptable to various types of containers, and easy to assemble and disassemble.

[0117] Implementation Method 5

[0118] This embodiment also discloses an internal support device A. This embodiment is a further improvement on the first embodiment, wherein the main body 1 can be magnetically adjusted to allow the hanging component 2 to be positioned inside the container. Specifically, see... Figure 6 As shown, the mounting component 2 of the inner support device A includes:

[0119] The abutment joint 21 can be magnetically attracted;

[0120] Spring 22, with its two ends connected to abutment 21 and main body 1 respectively;

[0121] Furthermore, subject 1 includes:

[0122] Frame 12 has a receiving groove 121 and a central groove 122;

[0123] Electromagnet 13 is disposed in the central slot 122;

[0124] When energized, the electromagnet 13 generates a magnetic force to attract the hanging part 2 onto the frame 12 and to house the spring 22 in the receiving groove 121.

[0125] In order for the inner support device A to be attached to the inside of the bottle, in this embodiment, the attachment component 2 may include an abutment 21 and a spring 22. The abutment 21 tends to move away from the main body 1 under the drive of the elastic potential energy of the spring 22. The frame 12 of the main body 1 has a receiving groove 121 for accommodating the abutment 21 and a central groove 122 for accommodating the spring 22. The receiving groove 121 is directly connected to the outside of the main body 1, and the central groove 122 is connected to the receiving groove 121 and is disposed inside the main body 1.

[0126] When the electromagnet 13 is energized, it generates a magnetic force to attract the abutment 21 into the receiving groove 121 on the frame 12, and the spring 22 is accommodated in the central groove 122. When the electromagnet 13 is de-energized, the magnetic force disappears, and the abutment 21 expands outward from the main body 1 under the action of the elastic potential energy of the spring 22, and abuts against the inner wall of the container or the container lid. With the above arrangement, when there are multiple hanging parts 2, the hanging parts 2 can be attracted by energizing the electromagnet 13, making it easy to remove the hanging parts 2. When the power is off, the hanging parts 2 expand outward synchronously, abutting against the inner wall of the container, so that the inner support device A can be permanently fixed inside the container under the action of the elastic force of the spring 22.

[0127] In an optional embodiment, the contact surface of the abutment 21 used to hold the sample may be provided with a layer of silicone or rubber material to increase the friction between the abutment 21 and the container.

[0128] Considering the generally long release test cycle, when using the spring 22 to push the abutment 21 to fix the hanging component 2, after a long test cycle, the hanging component 2 may become difficult to remove because the abutment 21 sticks to the container wall, or the hanging component 2 may be difficult to remove due to the excessive elasticity of the spring 22, or even damage the container. Accordingly, the electromagnet 13 solution of this embodiment can more conveniently remove the inner support device A. Only by energizing the electromagnet 13, the magnetic attraction of the electromagnet 13 can attract each abutment 21, detach it from the container wall, and adsorb it into the receiving groove 121, thus removing it from the container. The operation is convenient. The inner support device A does not need continuous power supply during the entire use process, and is only powered when it is removed. Therefore, the inner support device A has the advantage of being able to be used continuously for a long time.

[0129] Optionally, the elastic component 11 of the inner support device A is a spring 22, and at least three springs 22 are arranged as a group to connect the hanging component 2 and the main body 1.

[0130] To more stably position the inner support device A inside the container, at least three springs 22 can be grouped together, with each group of springs 22 connected between a corresponding hook-and-loop component 2 and the main body 1. When a group of springs 22 is compressed simultaneously, the combined compressed springs 22 provide stronger elastic potential energy. Under the elastic force of the multiple springs 22, the hook-and-loop component 2 exerts a stronger force on the inner wall of the container, resulting in a more reliable connection. Therefore, by using multiple springs 22, the inner support device A can be more stably fixed inside the container.

[0131] Finally, it should be noted that those skilled in the art will understand that many technical details have been presented in the embodiments of this patent to facilitate a better understanding of the invention. However, even without these technical details and various variations and modifications based on the above embodiments, the technical solutions claimed in the claims of this patent can be substantially achieved. Therefore, in practical applications, various changes can be made to the above embodiments in form and detail without departing from the spirit and scope of this patent.

Claims

1. An internal support device, characterized in that, The internal support device can be installed inside the container for hoisting samples, and includes: main body; A mounting component, connected to the main body, is used to hang on the wall of the container; The installation components include: Mounting components, connected to the main body, are used to mount the sample; A connecting component, with its two ends connected to the mounting component and the main body respectively, is used to adjust the distance between the main body and the mounting component.

2. The internal support device according to claim 1, characterized in that, The connecting component includes: A telescopic component, the end of which is away from the main body is connected to the mounting component, the telescopic component being able to change its length under the action of external force, so as to change the height of the sample mounted on the mounting component inside the container.

3. The internal support device according to claim 2, characterized in that, The telescopic component is a metal wire twisted into a spiral shape.

4. The internal support device according to claim 2, characterized in that, The connecting component further includes: An adjusting component is provided, wherein the telescopic component is connected to the main body via the adjusting component, and is used to adjust the length of the telescopic component.

5. The internal support device according to claim 1, characterized in that, The mounting components include: A mounting section for mounting a sample; The mounting part is suspended from the connecting component via the lifting part.

6. The internal support device according to claim 5, characterized in that, The mounting part is a clamp, and the lifting part includes at least two clamping rods, the end of each clamping rod being connected to the clamp. Furthermore, the mounting component also includes: A tightening sleeve that holds the various clamping rods of the lifting section together; Each clamping rod of the lifting part opens on the side away from the main body and can be clamped under the constraint generated when the tightening sleeve moves toward the opening side.

7. The internal support device according to claim 1, characterized in that, The subject also includes: An elastic component connects the main body and the hanging component, causing the hanging component to move away from the main body and enabling the main body to be supported on the inner wall of the container via the hanging component.

8. The internal support device according to claim 7, characterized in that, The elastic component is a spiral metal wire, which supports the inner wall of the container through its own elastic force.

9. The internal support device according to claim 1, characterized in that, The mounting component includes: An abutment joint, wherein the abutment joint can be magnetically attracted; A spring, the two ends of which are respectively connected to the abutment and the main body; Furthermore, the main body includes: The frame has a receiving slot and a central slot; An electromagnet, wherein the electromagnet is disposed within the central slot; When energized, the electromagnet generates a magnetic force to attract the hanging component to the frame and accommodate the spring in the receiving groove.

10. The internal support device according to claim 8, characterized in that, The elastic component is a spring, and at least three springs are arranged as a group to connect the hanging component and the main body.

11. The internal support device according to claim 1, characterized in that, The outer wall of the hanging component away from the main body is an arc surface, and at least three hanging components are evenly distributed around the wall surface of the main body.

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