Rotary pump with electrically heated removable pump head for ECLS applications

Abstract

Devices, systems, and methods for warming a patient during an ECLS procedure. Depending on a particular need (cardiac and pulmonary support or pure cardiac support), the patient may be warmed by a heat exchanger in which the patient's blood is in intimate-indirect-contact with the warming fluid, or in a pure cardiac assist procedure, the patient's blood is warmed directly. According to the suggested scheme of the two heating methods, the centrifugal pump with the integrated heating device is provided, and the centrifugal pump is provided with a detachable pump head. The invention allows for smaller design, simpler handling, use of sterile warming fluid without air contact, turbulence enhanced heat transfer, and includes intrinsic safety aspects for ECLS patients.

Description

Technical Field

[0001] This disclosure relates to a pump having an integrated heating element for heating a pumped fluid, and more particularly, to a pump having an integrated heating element consisting of two separable components, through which fluid flows, a first component, and a second component that does not come into contact with the pumped fluid containing the pump driver. Background Technology

[0002] Extracorporeal life support (ECLS) is a technique that provides extended cardiac and / or respiratory support to individuals whose own heart and / or lungs are insufficient to sustain life. The most common ECLS method is the ECMO procedure, in which the patient is connected to an extracorporeal circulation system that includes a blood pump and an oxygenator to provide blood perfusion and gas exchange. In the case of ECLS, the patient's lungs are fully functional and only cardiac support is required; therefore, the cardiac support system includes only a blood pump for providing blood perfusion and does not include an oxygenator.

[0003] During ECMO or cardiac assist procedures, a patient's core temperature often drops, for example, because their blood is circulating outside the body. In some cases, even before ECMO procedures, such as if the patient's body temperature is already low, their core temperature may still be low. Therefore, the blood can be warmed before being reintroduced into the patient to maintain an appropriate core temperature.

[0004] One method of heating blood is through a heat exchanger, in which a heated fluid is brought into indirect contact with the blood to raise its temperature. The heat exchanger can be a stand-alone device. Figure 13 ) or built into the oxygenator ( Figure 12 Then, the heated blood is returned to the patient.

[0005] The heating fluid itself can be heated using various methods, such as providing heating elements in the flow path of the heating fluid. However, existing methods for heating the heating fluid have several drawbacks, such as inconsistent heating, long response times, and generally large and bulky size. Furthermore, existing heating devices are not inherently (or even optionally) sterile. Therefore, the heating fluid can be contaminated, meaning that the heating device needs to be sterilized periodically to ensure safe operation. This leads to increased downtime and increased device workload. Due to these shortcomings and deficiencies of the prior art, there is a need for an improved device, system, and method for efficiently and sterilely heating patients during ECLS procedures.

[0006] Another method of heating blood is to heat the blood directly in a pump without using a heat exchanger. Figure 14 There is no known prior art for this procedure, therefore the new method and the device using the new method are described in the disclosure of this invention. Summary of the Invention

[0007] This disclosure addresses the aforementioned shortcomings and deficiencies of the prior art by providing apparatus, systems, and methods for effectively warming a patient while maintaining sterility. In particular, this disclosure relates to apparatus, systems, and methods for warming a patient during ECLS procedures. Depending on the specific needs (cardiac and pulmonary support or purely cardiac support), patient warming can be achieved via a heat exchanger, wherein the patient's blood is in close-indirect contact with a warming fluid, or, in purely cardiac support procedures, the patient's blood can be directly warmed.

[0008] The proposed solutions for the two heating methods mentioned above are centrifugal pumps with integrated heating devices and detachable pump heads.

[0009] The present invention has the following advantages: The integration of the pump and heating unit allows for a smaller design. First, this is advantageous for transporting patients receiving ECLS. Second, because the perfusion capacity of the heater circuit can be reduced, this allows for a faster response after parameter changes, and thus allows for more dynamic heating performance.

[0010] The removable pump head allows for simpler operation, as it can be replaced during use. Furthermore, the heating pump can be easily reused by removing the used pump head and replacing it with a new one.

[0011] • The use of a removable, disposable pump head allows for a sterile, single-use circuit, meaning a sterile heating fluid with no air contact. Therefore, there is no possibility of bacterial growth inside the heating fluid.

[0012] Combining heating and pumping within the same chamber allows for enhanced heat transfer from the heating element to the fluid to be heated through turbulence. Furthermore, microscopic and macroscopic turbulence improves the mixing of the heated fluid with the unheated fluid.

[0013] This invention also has safety aspects for ECLS patients. Since the heat transfer rate depends on the pump's rotational speed, the risk of overheating the patient can be controlled by adjusting the rotational speed. In extreme cases, when the pump stops, there is no more heat transfer. Furthermore, as an additional safety feature, this invention reduces the risk of "hot spots."

[0014] Different embodiments of a centrifugal pump with an integrated heating device and a detachable pump head are presented.

[0015] The heating device can be an induction heating device or a resistance heating device. Induction heating devices can be based on alternating magnetic fields or stationary magnetic fields. Different embodiments of inductors and / or conductors are discussed for induction heating devices based on alternating magnetic fields and induction heating devices based on stationary magnetic fields.

[0016] Furthermore, an embodiment of a centrifugal pump with an integrated heating device is proposed, wherein the centrifugal pump has a detachable pump head, and wherein the induction heating device is combined with an electromagnetic pump driver.

[0017] In one non-limiting example or aspect of this disclosure, a heated fluid pump assembly for a fluid flow system may include a first component including an impeller configured to circulate fluid through an impeller chamber; a second component including a driver for the impeller; and an induction heating element including a conductor as part of the first component and an inductor as part of the second component and fluidly isolated from the conductor, wherein the first component is detachable from the second component, wherein the inductor is configured to generate a magnetic field to induce eddy currents in the conductor, wherein the heating element is configured to induce eddy currents in the conductor to heat the conductor, and wherein the conductor is configured to contact the fluid as the fluid circulates through the impeller.

[0018] In one non-limiting example or aspect of this disclosure, the induction heating element may include an inductor coil. A controller may be provided and configured to supply power to the inductor coil to generate a magnetic field. The inductor coil may include one or more windings. The one or more windings may be arranged in a single layer. The one or more windings may be arranged in multiple layers. The inductor coil may be a printed circuit board. A conductor may be rotatably coupled to an impeller. The impeller as a whole may be made of a conductive material, such that the impeller is also a conductor. The conductive impeller may include an arrangement of increased surfaces, thereby increasing the heat exchange area and inducing microturbulence in the fluid. The conductor may be configured as a conductive layer applied to the inner surface of the impeller chamber. A controller may be provided and configured to supply power to the conductive layer. The conductor may be configured as a fixed heating element attached to the impeller chamber.

[0019] In one non-limiting example or aspect of this disclosure, a heated fluid pump assembly for a fluid flow system may include a first component including an impeller configured to circulate fluid through an impeller chamber; a second component including a driver for the impeller; and an induction heating element including a conductor as part of the first component and a magnet as part of the second component and fluidly isolated from the conductor, wherein the first component is detachable from the second component, wherein the magnet is configured to generate a magnetic field to induce eddy currents in the conductor, wherein the heating element is configured to induce eddy currents in the conductor to heat the conductor, and wherein the conductor is configured to contact the fluid as the fluid circulates through the impeller.

[0020] In one non-limiting example or aspect of this disclosure, the conductor may include lugs extending between the sidewalls of the magnet. The magnet may be a permanent magnet.

[0021] In one non-limiting example or aspect of this disclosure, a heated fluid pump assembly for a fluid flow system may include a first component including an impeller configured to circulate fluid through an impeller chamber; a second component including a driver for the impeller; and an electric heating element including a resistor as part of the first component and an electrical energy source as part of the second component, wherein the first component is detachable from the second component, wherein the resistor is electrically connected to the electrical energy source, wherein the electric heating device is configured to heat the resistor, and wherein the resistor is configured to contact the fluid as the fluid circulates through the impeller.

[0022] In one non-limiting example or aspect of this disclosure, the impeller as a whole may be made of a resistive material, such that the impeller itself is a resistor. The conductive impeller may have an arrangement that increases the surface area, thereby increasing the heat exchange area and inducing microturbulence in the fluid. The resistor may include a conductive layer applied to the impeller. The resistor may be at least a portion of the impeller. The resistor may include a conductive layer applied to the inner surface of the impeller chamber. The resistor may be electrically connected to a shaft for rotating the impeller.

[0023] In one non-limiting example or aspect of this disclosure, a heated fluid pump assembly for a fluid flow system may include a first component including an impeller configured to circulate fluid through an impeller chamber; a second component including an electromagnetic actuator for the impeller; and an inductive heating element including a conductor as part of the first component and an inductor as part of the second component, wherein the first component is detachable from the second component, wherein the heating element inductor is configured to generate a magnetic field to induce eddy currents in the conductor, wherein the heating element is configured to induce eddy currents in the conductor to heat the conductor, wherein the conductor is configured to contact the fluid as the fluid circulates through the impeller, wherein the impeller includes one or more magnets interacting with the impeller actuator, and wherein the electromagnetic actuator for the impeller is configured to generate a rotating magnetic field to rotate the impeller by induction.

[0024] In one non-limiting example or aspect of this disclosure, the electromagnetic actuator may be a drive coil. A heating element inductor may also serve as the induction coil of the electromagnetic actuator. The heating element inductor and the induction coil of the electromagnetic actuator may be separate coils. The heating fluid pump assembly may include a controller configured to supply power to the heating element inductor coil to generate a magnetic field for heating. The heating fluid pump assembly may also include a controller configured to supply power to the drive coil to generate a rotating magnetic field for rotating the impeller.

[0025] In one non-limiting example or aspect of this disclosure, a heated fluid pump assembly for a fluid flow system is provided, wherein a first component including an impeller and an impeller chamber is connected via a pipe to a heat exchanger to form a heated fluid loop, and wherein the heated fluid loop is configured to circulate heated fluid through the impeller chamber and the heat exchanger. The heated fluid loop may be pre-filled with sterile heated fluid, and wherein the sterile heated fluid circulates through the heat exchanger.

[0026] In one non-limiting example or aspect of this disclosure, a heated fluid pump assembly for a fluid flow system for ECMO applications is provided, wherein the initial heated fluid circuit includes the aforementioned first component comprising an impeller and an impeller chamber, and includes conduits connecting the inlet and outlet of the impeller chamber, the conduits being pre-filled with sterile heated fluid, and wherein the initial heated fluid circuit is connected under sterile conditions to a heat exchanger integrated in an oxygenator, such that during ECMO, sterile heated fluid circulates through the heat exchanger.

[0027] In one non-limiting example or aspect of this disclosure, a heated fluid pump assembly for a fluid flow system includes at least one of an ECMO machine, a heart-lung machine, and a dialysis machine, wherein the circulating fluid is blood, and wherein the blood circulates and is heated in a circuit, the circuit including an external portion of the circuit, a patient's circulatory system, and at least one inflow and outflow device connecting the external portion of the circuit to the patient's circulatory system, wherein the external portion of the circuit includes a first component, an oxygenator, and a conduit, the first component including an impeller and an impeller chamber, and the conduit connecting the first component to the oxygenator and to the inflow and outflow device.

[0028] In one non-limiting example or aspect of this disclosure, a heated fluid pump assembly for a fluid flow system includes at least one of an ECLS machine, a cardiopulmonary bypass machine, and a dialysis machine, wherein the circulating fluid is blood, and wherein the blood circulates and is heated in a circuit, the circuit including an external portion of the circuit, a patient's circulatory system, and at least one inflow and outflow device connecting the external portion of the circuit to the patient's circulatory system, wherein the external portion of the circuit includes a first component and a conduit, the first component including an impeller and an impeller chamber, and the conduit connecting the first component to the inflow and outflow device.

[0029] This invention is also disclosed in the following provisions: Clause 1: A heated fluid pump assembly for a fluid flow system, the heated fluid pump assembly comprising: a first component including an impeller configured to circulate fluid through an impeller chamber; a second component including a driver for the impeller; and an induction heating element including a conductor as part of the first component and an inductor as part of the second component and fluidly isolated from the conductor, wherein the first component is detachable from the second component, wherein the inductor is configured to generate a magnetic field to induce eddy currents in the conductor, wherein the heating element is configured to induce eddy currents in the conductor to heat the conductor, and wherein the conductor is configured to contact the fluid as the fluid circulates through the impeller.

[0030] Clause 2: The heating fluid pump assembly according to Clause 1, wherein the induction heating element includes an inductor coil.

[0031] Clause 3: The heating fluid pump assembly according to Clause 2 further includes a controller configured to supply power to the inductor coil to generate the magnetic field.

[0032] Clause 4: The heating fluid pump assembly as described in Clause 2, wherein the inductor coil comprises one or more windings.

[0033] Clause 5: The heating fluid pump assembly according to Clause 4, wherein the one or more windings are arranged in a single layer.

[0034] Clause 6: The heating fluid pump assembly according to Clause 4, wherein the one or more windings are arranged in multiple layers.

[0035] Clause 7: The heating fluid pump assembly as described in Clause 4, wherein the inductor coil is a printed circuit board.

[0036] Clause 8: A heating fluid pump assembly according to any one of Clauses 1 to 7, wherein the conductor is rotatably coupled to the impeller.

[0037] Clause 9: A heating fluid pump assembly according to any one of Clauses 1 to 8, wherein the impeller is integrally made of a conductive material such that the impeller is also a conductor.

[0038] Clause 10: The heated fluid pump assembly according to Clause 9, wherein the conductive impeller includes an arrangement of increased surfaces, thereby increasing the heat exchange area and inducing microturbulence in the fluid.

[0039] Clause 11: A heated fluid pump assembly according to any one of Clauses 1 to 10, wherein the conductor is configured as a conductive layer applied to the inner surface of the impeller chamber.

[0040] Clause 12: The heating fluid pump assembly according to Clause 11 further includes a controller configured to provide power to the conductive layer.

[0041] Clause 13: A heated fluid pump assembly according to any one of Clauses 1 to 12, wherein the conductor is configured as a fixed heating element attached to the impeller chamber.

[0042] Clause 14: A heated fluid pump assembly for a fluid flow system, the heated fluid pump assembly comprising a first component including an impeller configured to circulate fluid through an impeller chamber; a second component including a driver for the impeller; and an induction heating element including a conductor as part of the first component and a magnet as part of the second component and fluidly isolated from the conductor, wherein the first component is detachable from the second component, wherein the magnet is configured to generate a magnetic field to induce eddy currents in the conductor, wherein the heating element is configured to induce eddy currents in the conductor to heat the conductor, and wherein the conductor is configured to contact the fluid as the fluid circulates through the impeller.

[0043] Clause 15: The heating fluid pump assembly according to Clause 14, wherein the conductor includes a lug extending between the sidewalls of the magnet.

[0044] Clause 16: The heating fluid pump assembly according to Clause 15, wherein the magnet is a permanent magnet.

[0045] Clause 17: A heated fluid pump assembly for a fluid flow system, the heated fluid pump assembly comprising: a first component including an impeller configured to circulate fluid through an impeller chamber; a second component including a driver for the impeller; and an electric heating element including a resistor as part of the first component and an electrical energy source as part of the second component, wherein the first component is detachable from the second component, wherein the resistor is electrically connected to the electrical energy source, wherein the electric heating element is configured to heat the resistor, and wherein the resistor is configured to contact the fluid as the fluid circulates through the impeller.

[0046] Clause 18: The heating fluid pump assembly according to Clause 17, wherein the impeller is integrally made of a resistive material such that the impeller itself is the resistor.

[0047] Clause 19: The heated fluid pump assembly according to Clause 18, wherein the conductive impeller has an arrangement of increased surface area, thereby increasing the heat exchange area and inducing microturbulence in the fluid.

[0048] Clause 20: A heated fluid pump assembly according to any one of Clauses 17 to 19, wherein the resistor includes a conductive layer applied to the impeller.

[0049] Clause 21: A heating fluid pump assembly according to any one of Clauses 17 to 20, wherein the resistor is at least a portion of the impeller.

[0050] Clause 22: A heated fluid pump assembly according to any one of Clauses 17 to 21, wherein the resistor includes a conductive layer applied to the inner surface of the impeller chamber.

[0051] Clause 23: A heating fluid assembly according to any one of Clauses 17 to 22, wherein the resistor is electrically connected to a shaft for rotating the impeller.

[0052] Clause 24: A heated fluid pump assembly for a fluid flow system, the heated fluid pump assembly comprising: a first component including an impeller configured to circulate fluid through an impeller chamber; a second component including an electromagnetic actuator of the impeller; and an induction heating element including a conductor as part of the first component and an inductor as part of the second component, wherein the first component is detachable from the second component, wherein the heating element inductor is configured to generate a magnetic field to induce eddy currents in the conductor, wherein the heating element is configured to induce eddy currents in the conductor to heat the conductor, and wherein the conductor is configured to contact the fluid as the fluid circulates through the impeller, wherein the impeller includes one or more magnets interacting with the actuator of the impeller, and wherein the electromagnetic actuator of the impeller is configured to generate a rotating magnetic field to rotate the impeller by induction.

[0053] Clause 25: The heating fluid pump assembly according to Clause 24, wherein the electromagnetic actuator includes a drive coil.

[0054] Clause 26: The heating fluid pump assembly according to Clause 25, wherein the heating element inductor also serves as the induction coil of the electromagnetic actuator.

[0055] Clause 27: The heating fluid pump assembly according to Clause 25, wherein the heating element inductor and the induction coil of the electromagnetic actuator are separate coils.

[0056] Clause 28: The heating fluid pump assembly according to Clause 25, wherein the heating fluid pump assembly further includes a controller configured to supply power to the heating element inductor coil to generate the magnetic field for heating.

[0057] Clause 29: The heated fluid pump assembly according to Clause 25, wherein the heated fluid pump assembly further includes a controller configured to supply power to the drive coil to generate a rotating magnetic field for rotating the impeller.

[0058] Clause 30: A heated fluid pump assembly for a fluid flow system as described in Clauses 1, 14, 17 or 24, wherein the first component, including an impeller and an impeller chamber, is connected via a pipe to a heat exchanger to form a heated fluid loop, and wherein the heated fluid loop is configured to circulate heated fluid through the impeller chamber and the heat exchanger.

[0059] Clause 31: A heated fluid pump assembly for a fluid flow system as described in Clause 30, wherein the heated fluid circuit is pre-filled with sterile heated fluid, and wherein the sterile heated fluid circulates through the heat exchanger.

[0060] Clause 32: A heated fluid pump assembly for a fluid flow system for ECMO applications as described in Clause 30, wherein the initial heated fluid circuit includes the first component comprising an impeller and an impeller chamber, and includes conduits connecting the inlet and outlet of the impeller chamber, the conduits being pre-filled with sterile heated fluid, and wherein the initial heated fluid circuit is connected under sterile conditions to the heat exchanger integrated in the oxygenator such that, during ECMO conditions, sterile heated fluid circulates through the heat exchanger.

[0061] Clause 33: A heated fluid pump assembly for a fluid flow system as described in Clauses 1, 14, 17, or 24, comprising at least one of an ECMO machine, a heart-lung machine, and a dialysis machine, wherein the circulating fluid is blood, and wherein the blood circulates and is heated in a circuit, the circuit comprising an external portion of the circuit, the patient's circulatory system, and at least one inflow and outflow device connecting the external portion of the circuit to the patient's circulatory system, wherein the external portion of the circuit comprises a first component, an oxygenator, and a conduit, the first component comprising an impeller and an impeller chamber, and the conduit connecting the first component to the oxygenator and to the inflow and outflow device.

[0062] Clause 34: A heated fluid pump assembly for a fluid flow system according to Clauses 1, 14, 17 or 24, comprising at least one of an ECLS machine, a heart-lung machine, and a dialysis machine, wherein the circulating fluid is blood, and wherein the blood circulates and is heated in a circuit, the circuit comprising an external portion of the circuit, the patient's circulatory system, and at least one inflow and outflow device connecting the external portion of the circuit to the patient's circulatory system, wherein the external portion of the circuit comprises a first component and a conduit, the first component comprising an impeller and an impeller chamber, the conduit connecting the first component to the inflow and outflow device.

[0063] Further details and advantages of the various non-limiting examples described herein will become clear after carefully reading the following detailed description of the various non-limiting examples in conjunction with the accompanying drawings. Attached Figure Description

[0064] Figure 1 This is a schematic diagram of an extracorporeal circulation system according to an embodiment of the present disclosure; Figure 2 This is a schematic diagram of an extracorporeal circulation system according to an embodiment of the present disclosure; Figure 3 This is a cross-sectional view of a fluid heating pump assembly according to an embodiment of the present disclosure; Figure 4 This is a schematic diagram of a fluid heating pump assembly according to an embodiment of the present disclosure; Figure 5 This is a perspective cross-sectional view of a fluid heating pump assembly according to an embodiment of the present disclosure; Figure 6 yes Figure 5 A side cross-sectional view of the fluid heating pump assembly; Figure 7 yes Figure 5 A perspective view of a fluid heating pump assembly, wherein, for clarity, the impeller chamber and its housing are not shown; Figure 8 This is a cross-sectional view of a fluid heating pump assembly according to an embodiment of the present disclosure; Figure 9 This is a cross-sectional view of a fluid heating pump assembly according to an embodiment of the present disclosure; Figure 10 This is a schematic diagram of a fluid heating pump assembly according to an embodiment of the present disclosure; Figure 11 This is a schematic diagram of a fluid heating pump assembly according to an embodiment of the present disclosure; Figure 12 This is a schematic diagram of a fluid heat transfer system according to an embodiment of the present disclosure; Figure 13 This is a schematic diagram of a fluid heat transfer system according to an embodiment of the present disclosure; Figure 14 This is a schematic diagram of a fluid heat transfer system according to an embodiment of the present disclosure; Figure 15 This is a schematic diagram of a fluid heating pump assembly according to an embodiment of the present disclosure; and Figure 16 This is a schematic diagram of a fluid heating pump assembly according to an embodiment of the present disclosure.

[0065] Referring to the accompanying drawings, in which similar reference numerals denote similar parts in all of the several views, this disclosure generally relates to an extracorporeal circulation system and a fluid heating pump assembly for the system. Detailed Implementation

[0066] For ease of description below, the terms “above,” “below,” “right,” “left,” “vertical,” “horizontal,” “top,” “bottom,” “lateral,” “longitudinal,” and their derivatives shall refer in this disclosure to orientations in the accompanying drawings. Spatial or directional terms such as “left,” “right,” “inner,” “outer,” “up,” and “down” should not be construed as limiting, as various alternative orientations may be adopted in the disclosed embodiments.

[0067] As used herein, the singular forms “a,” “one,” and “the” include plural indicators unless the context clearly indicates otherwise.

[0068] All figures used in the specification and claims should be understood to be modified by the term "about" in all cases. The terms "about," "approximately," and "substantially" refer to a range of ±10% of the stated value.

[0069] As used herein, “at least one” is a synonym for “one or more.” For example, the phrase “at least one of A, B, and C” means any one of A, B, or C, or any combination of two or more of A, B, or C. For example, “at least one of A, B, and C” includes one or more A's alone; or one or more B's alone; or one or more C's alone; or one or more A's and one or more B's; or one or more A's and one or more C's; or one or more B's and one or more C's; or all of A, B, and C are one or more. Similarly, as used herein, the term “at least two” is a synonym for “two or more.” For example, the phrase “at least two of D, E, and F” means any combination of two or more of D, E, and F. For example, “at least two of D, E, and F” includes one or more D's and one or more E's; or one or more D's and one or more F's; or one or more E's and one or more F's; or all of D, E, and F are one or more.

[0070] It should also be understood that the specific devices and processes shown in the accompanying drawings and described in the following description are merely examples of this disclosure. Therefore, the specific dimensions and other physical characteristics associated with the examples disclosed herein should not be considered limiting.

[0071] The terms “first”, “second”, etc., do not refer to any particular order or chronology, but rather to different conditions, characteristics, or elements.

[0072] The term "at least" is a synonym for "greater than or equal to". The term "not greater than" is a synonym for "less than or equal to".

[0073] It should be understood that, unless otherwise expressly stated to the contrary, this disclosure may take the form of alternative variations and sequences of steps. It should also be understood that the specific apparatus and processes shown in the accompanying drawings and described in the description below are merely exemplary aspects of this disclosure. Therefore, specific dimensions and other physical characteristics relating to the examples disclosed herein should not be considered limiting.

[0074] First see Figure 1 The diagram illustrates an extracorporeal circulation system 1000 (which may include, or be referred to as, a cardiopulmonary bypass machine, a cardiac bypass system, or a cardiopulmonary diversion system, and should be broadly understood to include cardiopulmonary diversion (CPB) systems, minimal extracorporeal circulation (MECC) systems, extracorporeal membrane oxygenation (ECMO) systems (respiratory and cardiac), and pump-assisted lung protection (PALP) systems) comprising an oxygenator / heat exchanger 100 and a fluid heating pump assembly 200. The oxygenator / heat exchanger 100 is connected to the patient 300 via an inlet blood line 110 connected to a vein and an outlet blood line 120 connected to an artery (or in some cases, a vein) of the patient 300. The oxygenator / heat exchanger 100 may include, for example... Figure 1 The integrated heat exchanger shown may be connected to an external heat exchanger. In other embodiments, the oxygenator may not be associated with a heat exchanger. During extracorporeal circulation procedures (e.g., ECMO procedures), the oxygenator / heat exchanger 100 receives deoxygenated blood from the patient 300 via inlet blood line 110, oxygenates the blood, and returns the oxygenated blood to the patient 300 via outlet blood line 120. The oxygenator 100 may include or be connected to a blood circulation pump (…). Figure 1(Not shown in the diagram), this blood circulation pump circulates blood through the inlet blood line 110, the oxygenator / heat exchanger 100, and the outlet blood line 120. Commercial examples of suitable blood circulation pumps and their associated components include, but are not limited to, the Maquet Cardiohelp® and Maquet Rotaflow® systems supplied by Maquet Cardiopulmonary GmbH. Thus, the oxygenator / heat exchanger 100 and associated components of the system 1000 replicate the patient's cardiac and / or pulmonary function during ECMO (or other extracorporeal circulation) procedures. Figure 1 The extracorporeal circulation system 1000 shown constitutes a simplified, non-limiting illustration, as such systems are typically much more complex.

[0075] See also Figure 1 The oxygenator / heat exchanger 100 may include a heat exchanger section configured to heat and / or cool patient blood to maintain a clinically required blood temperature. To heat the patient's blood, a fluid heating pump assembly 200 supplies heated fluid to the oxygenator / heat exchanger 100. The heated fluid directly or indirectly heats the blood in the heat exchanger section of the oxygenator / heat exchanger 100 and returns to the fluid heating pump assembly 200. The fluid heating pump assembly 200 includes an impeller 210; an outlet fluid line 220 through which the impeller 210 supplies heated fluid to the heat exchanger section of the oxygenator / heat exchanger 100; and a return fluid line 230 through which the heated fluid returns from the heat exchanger section of the oxygenator 100 to the impeller 210. The fluid heating pump assembly 200 also includes a motor 240 that rotatably drives an impeller 210; a heating element 250 that heats the fluid; and an electronic controller 260. The electronic controller 260 may include, for example, circuitry for driving the motor 240 and regulating the heating element 250 to control the temperature of the heated fluid. Further details of the fluid heating pump assembly 200 will be referenced herein. Figures 3 to 9 supply.

[0076] See now Figure 2 The figure shows another embodiment of the extracorporeal circulation system 1010. (Compared to...) Figure 1 The system is different from 1000. Figure 2The fluid heating pump assembly 200 of system 1010 is directly connected to the patient 300, and the fluid heating pump assembly 200 circulates blood back and forth from the patient 300. Specifically, the inlet blood line 110 and the outlet blood line 120 are connected to the inlet 214 and outlet 216 of the fluid heating pump assembly 200, respectively. Therefore, the fluid heating pump assembly 200 directly heats the patient's blood without the need for a separate heat exchanger. As those skilled in the art will understand, various other system arrangements are possible, including external heat exchangers, integrated heat exchangers / oxygenators, etc.

[0077] See Figures 1 to 2 An embodiment of the fluid heating pump assembly 200 comprises a first component 130 (i.e., a pump head) and a second component 140. The first component 130 includes an impeller chamber 218 in which an impeller 210 is disposed. The second component 140 includes a driver for the impeller. The first component is detachable from the second component. The impeller chamber 218 defines an inlet 214 that receives heated fluid from the oxygenator / heat exchanger 100 and an outlet 216 through which the heated fluid returns to the oxygenator / heat exchanger 100. The impeller 210 is coupled to an impeller shaft 212 rotated by a motor 240 (see [link to motor description]). Figure 1 and Figure 2 The impeller shaft is typically part of the first component 130. In some embodiments, the impeller shaft 212 may be part of the second component 140.

[0078] See now Figures 3 to 7 and Figure 16 The fluid heating pump assembly 200 also includes a sensing element, which is part of the second component 140, such as an inductor coil 252; and a conductor 254, which is part of the first component 130. The inductor coil 252 and the conductor 254 together form the heating element 250. Figure 3 Conductor 254 is disposed within the first component 130 of the fluid heating pump assembly 200 such that the heated fluid circulating through impeller 210 contacts conductor 254 before exiting outlet 216 of impeller chamber 218.

[0079] Inductor coil 252 receives current from controller 260 (see...) Figure 1 and Figure 2 The inductor coil 252 generates an alternating magnetic field in response to the received current. The magnetic field generated by the inductor coil 252 induces eddy currents in the conductor 254, thereby heating the conductor 254 (i.e., raising its temperature). Figure 3 As shown, conductor 254 can be attached to impeller 210 such that when heated fluid circulates through impeller 210, heated fluid comes into contact with conductor 254. Due to the contact between heated fluid and conductor 254, heated fluid is heated.

[0080] Heating efficiency can be attributed to both macroscopic and microturbulence. As used herein, “macroscopic turbulence” refers to turbulence that can be seen with the naked eye. Conversely, “microturbulence” as used herein refers to turbulence that occurs at the molecular level and is therefore not directly visible to the naked eye. However, microturbulence can be characterized by measuring various properties of the fluid flow. Macroscopic turbulence of the heated fluid within impeller chamber 218 allows the heated fluid to mix with itself, resulting in a relatively uniform heat distribution within the heated fluid. As a result, the temperature of the entire heated fluid can be substantially uniform as it exits outlet 216, with no obvious hot and / or cold spots. This ensures more reliable and predictable heating of the patient's blood within oxygenator 100. Additionally, microturbulence directly surrounding conductor 254 helps minimize stagnant zones in the fluid to improve heat transfer efficiency. Thus, conductor 254 is both a heat source and a source of microturbulence. This serves as an inherent safety measure, as stopping the rotation of impeller 210 reduces microturbulence, which in turn reduces the heat transfer efficiency through the fluid. Both macro-turbulence and micro-turbulence reduce the occurrence of localized heating of the fluid and improve the uniformity of the heated fluid.

[0081] As described in

[0036] and see further. Figure 3 The inductor coil 252 is fluidly isolated from the impeller chamber 218, thereby preventing the heating fluid from contacting the inductor coil 252. For example, the inductor coil 252 can be fluidly isolated from the conductor 254 by a wall 274, which forms part of the base 270 and / or the impeller chamber 218. The magnetic field generated by the inductor coil 252 can penetrate the wall 274 to induce eddy currents in the conductor 254, thereby heating the conductor 254 as described herein.

[0082] See also Figure 3 In some embodiments, the inductor coil 252 may be disposed in a recess 272 on the base 270 of the fluid heating pump assembly 200. The base 270 may be made of a ferromagnetic material to improve induction heating efficiency and generate an electromagnetic field.

[0083] See also Figure 3The inductor coil 252 may include a continuous conductor wound to form one or more windings 252a, 252b, 252c, 252d, 252e, 252f arranged concentrically around the impeller shaft 212. The number and arrangement of the windings 252a, 252b, 252c, 252d, 252e, 252f can vary and determine the strength, direction, and associated characteristics of the magnetic field induced in the inductor coil 252 when the controller 260 supplies electrical power to it. These characteristics of the magnetic field, as well as the proximity of the inductor coil 252 to the conductor 254, affect the heating of the conductor 254 and thus the heating of the heated fluid. In particular, electromagnetic coupling needs to be established between the inductor coil 252 and the conductor 254 to transfer energy.

[0084] exist Figure 3 In the embodiment shown, the windings 252a, 252b, 252c, 252d, 252e, and 252f of the inductor coil 252 are arranged in a multi-layer spiral manner, wherein windings 252a and 252b form the first layer closest to the conductor 254, windings 252c and 252d form the middle layer, and windings 252e and 252f form the third layer further away from the conductor 254.

[0085] Figure 4 Another arrangement of the inductor coil 252 is shown, wherein windings 252a, 252b, 252c, 252d, 252e, and 252f are all arranged in a single-layer spiral manner. Figures 5 to 7 It shows the relationship with Figure 4 Similar embodiments, but including additional windings 252g, 252h, 252i, 252j, and 252k in a single-layer winding. Likewise... Figure 4 , Figure 5 and Figure 7 As shown, a first lead 256 and a second lead 258 extend from the respective ends of the wires forming the inductor coil 252, wherein leads 256 and 258 are attached to a controller 260 to form a circuit together with the controller 260. For example, the first lead 256 may extend from the innermost winding 252a, and the second lead 258 may extend from the outermost winding 252k.

[0086] although Figures 3 to 7 A specific winding arrangement of the inductor coil 252 is shown, but this disclosure is not intended to limit it to these winding arrangements. Rather, the winding arrangement of the inductor coil 252 can take any form suitable for generating a sufficient electromagnetic field in the inductor coil 252 to produce the necessary amount of inductance to heat the conductor 254. Various modifications can be made to the winding arrangement to achieve the desired inductance. For example, using ferrite around the windings can increase the generated inductance, thereby reducing the number of windings required.

[0087] In some embodiments, the inductor coil 252 may be configured as a printed circuit board (i.e., a PCB coil). Furthermore, the inductor coil 252 is merely one example of a sensing element that can be used to heat the conductor 254 by induction. In other embodiments, the inductor coil 252 may replace another sensing element used to generate eddy currents in the conductor 254.

[0088] The inductor coil 252 may be a non-disposable component and not replaced with the pump head. In some embodiments, the inductor coil 252 may replace an alternative component with sufficient inductive characteristics to transfer energy to the conductor 254.

[0089] Conductor 254 is made of a material that exhibits a temperature rise in the presence of the magnetic field generated by inductor coil 252. That is, conductor 254 is made of a material capable of being heated by induction. For example, conductor 254 can be made of a ferrous metal, such as steel. Figures 3 to 7 As shown, conductor 254 may include a generally flat plate attached to impeller 210 in a plane substantially perpendicular to impeller shaft 212. In other embodiments, conductor 254 may be embedded in impeller 210, may be a conductive layer on impeller, or impeller 210 itself may serve as conductor 254. Conductor 254 may be a disposable component, disposed of together with the rest of the head of pump assembly 200.

[0090] See now Figure 16 Another embodiment of the fluid heating pump assembly 200 is similar to Figures 3 to 7 The embodiment is similar, but conductor 259 is attached within impeller chamber 218, rather than coupled to impeller 210. Therefore, Figure 16 In this embodiment, conductor 259 is fixed. Conductor 259 may consist of a single component placed at the bottom, sidewall, or top of the impeller chamber, or it may consist of several components distributed throughout the impeller chamber. In some embodiments, conductor 259 may be a conductive layer of the impeller chamber. The conductor 259 heats up in response to the current supplied to the inductor coil 252 in a manner similar to... Figures 3 to 7 The conductor 254 in the embodiment is heated in the same way. However, because conductor 259 is stationary and not rotating, Figure 16 The embodiments can generate less microturbulence in the fluid. In some embodiments, the conductors can be arranged to simultaneously implement two conductor types, namely conductor 254 and conductor 259.

[0091] See now Figure 9In another embodiment of the fluid heating pump assembly 200, the heating element 250 includes a conductor 255 rotatably coupled to an impeller 210. The conductor 255 includes lugs 266 extending into an annular groove 262 of the impeller chamber 218. The conductor 255 including the lugs 266 is made of a material capable of induction heating, such as a ferrous metal (e.g., steel). The annular groove 262 is disposed on the outer side of the impeller chamber 218 and is partially surrounded by a permanent magnet 290. The permanent magnet 290 may be generally U-shaped or horseshoe-shaped, such that the lugs 266 of the conductor 255 extend between opposing sidewalls 292 of the permanent magnet 290. The permanent magnet 290 exhibits a magnetic field, which induces eddy currents in the lugs 266 as they rotate through it. Therefore, rotation of the impeller 210, rotatably coupled to the lugs 266, causes the temperature of the lugs 266 to rise. Heat is transferred from lug 266 to the rest of conductor 255, and the heated fluid circulating in impeller chamber 218 increases in temperature upon contact with conductor 255.

[0092] In some embodiments, the permanent magnet 290 may be in a direction D parallel to the axis of rotation of the impeller 210 (see...). Figure 9 The permanent magnet 290 moves towards and away from conductor 255 to alter the effect of the magnetic field on lug 266. Moving the permanent magnet 290 towards conductor 255 generally increases the amplitude of eddy currents in lug 266, thereby increasing the temperature of conductor 255. Conversely, moving the permanent magnet 290 away from conductor 255 generally decreases the amplitude of eddy currents in lug 266, thereby decreasing the temperature of conductor 255. Since the permanent magnet 290 exhibits a magnetic field without an external power source, heating of conductor 255 is achieved solely through the electromagnetic field passively generated by the rotation of lug 266 relative to the permanent magnet 290, and consequently, heating of the heated fluid. Therefore, by stopping the rotation of the impeller, heat transfer to fluids susceptible to overheating (such as blood) can be stopped. Figure 9 In a similar embodiment, an electromagnet can be used instead of the permanent magnet 290, which requires an external power source to generate the magnetic field. The permanent magnet 290 (or electromagnet) may comprise a single magnet or multiple small magnets.

[0093] See now Figure 8 and Figure 15 Other embodiments of the fluid heating pump assembly 200 utilize resistance heating to increase the temperature of the fluid in the impeller chamber 218. Figure 8 In the illustrated embodiment, the heating element 250 includes a conductive layer 280 applied to the inner surface of the impeller chamber 218. The conductive layer 280 includes components connected to the controller 260 (see [link]). Figure 1At least two contacts 282, 284 are used to form a circuit, through which the controller 260 transmits current to the conductive layer 280 via the contacts 282, 284. In response to the current from the controller 260, the temperature of the conductive layer 280 rises. Therefore, the heated fluid circulating within the impeller chamber 218 is heated by contact with the conductive layer 280. The resistance of the conductive layer 280 and the electrical power provided by the controller 260 determine the heating characteristics of the conductive layer 280. Therefore, the conductive layer 280 can be selected to have a predetermined resistivity to achieve the heating required for the heated fluid within the impeller chamber 218. In some embodiments, the conductive layer 280 may be, for example, a coating applied to the impeller chamber 218 by a vapor deposition process.

[0094] exist Figure 15 In the illustrated embodiment, impeller 210 includes a conductive layer 281 (or at least a portion of impeller 210 is itself conductive). The conductive layer 281 is electrically connected to impeller shaft 212 such that the conductive layer 281 can pass through shaft 212 (e.g., through a sliding contact between the shaft and the electronic controller) from electronic controller 260 (see [link to electronic controller]). Figure 1 The controller 260 receives current. In response to the current from the controller 260, the temperature of the conductive layer 281 rises. Therefore, the heated fluid circulating within the impeller chamber 218 is heated by contact with the impeller 210. Heating of the impeller 210 can also induce microturbulence in the fluid on the impeller 210 surface, which improves the efficiency and uniformity of heat transfer to the fluid. The resistance of the conductive layer 281 and the electrical power provided by the controller 260 determine the heating characteristics of the conductive layer 281. Therefore, the conductive layer 281 can be selected to have a predetermined resistivity to achieve the heating required for the heated fluid within the impeller chamber 218. In some embodiments, the conductive layer 281 can be, for example, a coating applied to the impeller 210 by a vapor deposition process.

[0095] In some embodiments, conductive portions 280 and 281 and their contact with the power source can be combined in the same pump head.

[0096] As can be understood from this disclosure, including the accompanying drawings, the pump assembly 200 can take various forms to achieve heat transfer of the fluid into the impeller chamber 218. Figures 3 to 7 and Figures 9 to 11 The embodiment of the pump assembly 200 shown utilizes induction heating to heat the conductors 254, 255 attached (e.g., rotate-coupled) to the impeller 210. Conversely, Figure 8 and Figure 15 The illustrated embodiment of the pump assembly 200 utilizes resistance heating to heat the conductive layers 280, 281 on the impeller chamber 218 and / or impeller 210. Therefore, embodiments of this disclosure can be distinguished by the heating method used for fluid heat transfer (induction heating vs. resistance heating). In some embodiments, for example by using... Figures 3 to 7Conductor 254 and Figure 8 The conductive layer 280 allows for the combination of two types of heating devices.

[0097] Furthermore, heating can be achieved by heating either or both of the impeller 210 and the impeller chamber 218. Figures 3 to 7 , Figures 9 to 11 and Figure 15 In the illustrated embodiment, heating occurs on the impeller 210, therefore the heating element rotates. Conversely, in Figure 8 and Figure 16 In some embodiments, heating occurs at the impeller housing 218, therefore the heating element is fixed. In some embodiments, the pump assembly 200 may combine both rotating and fixed heating elements, such as by... Figures 3 to 7 Induction impeller heating device and Figure 8 It is combined with a resistance impeller chamber heating device.

[0098] See now Figure 10 and Figure 11 The figure schematically illustrates an alternative embodiment of the fluid heating pump assembly 200. Figure 10 and Figure 11 The fluid heating pump assembly 200 can be used with Figure 4 Similar to a fluid heating pump assembly, except that the impeller 210 is not connected to a motor drive shaft, but is instead rotated by an electromagnetic actuator. The impeller 210 includes one or more magnets 294 (e.g., permanent magnets) arranged at an operating distance from the electromagnetic actuator located outside the impeller chamber 218. The electromagnetic actuator interacts with the magnets 294 to rotate the impeller 210 by induction. Thus, the impeller 210 does not need to be coupled to a shaft extending outside the impeller chamber 218 for connection to a motor. Instead, the impeller 210 can be mechanically supported within the impeller chamber 218 (e.g., via one or more bearings), or the impeller 210 can be magnetically suspended (i.e., levitated) within the impeller chamber 218 for frictionless connection. In some embodiments, such as Figure 10 As shown, the inductor coil 252 itself also functions as an electromagnetic actuator. Therefore, the current supplied to the inductor coil 252 both heats the conductor 254 and rotates the impeller 210. In other embodiments, such as Figure 11 As shown, a separate drive coil 296 can be provided outside the impeller chamber 218 to serve as an electromagnetic actuator for inductively rotating the impeller 210. The drive coil 296 may include a connection to an electronic controller 260 (see [link to electronic controller]). Figure 1Leads 297 and 298 are used to supply power to drive coil 296. Drive coil 296 may include one or more windings arranged in various configurations (e.g., one or more layers) to achieve the electromagnetic induction level required and / or desired for driving the impeller. In other embodiments, the electromagnetic actuator may be an electromagnetic induction source other than the coil.

[0099] While embodiments of this disclosure have been generally described in conjunction with ECMO systems, the fluid heating pump assembly 200 and related components described herein can be used in a variety of extracorporeal blood flow systems, including ECMO, heart-lung machines, cardiopulmonary bypass machines, and pump-assisted lung protection machines. Furthermore, the fluid heating pump assembly 200 is not limited to heating fluids, but can alternatively be used to heat and / or cool any non-biological or biological fluid (e.g., blood in ECLS procedures). The fluid heating pump assembly 200 can also be used in areas outside of extracorporeal circulation to heat and pump fluids in a variety of other applications requiring efficient fluid heating in a compact device. Embodiments of the pump assembly 200 described in this disclosure also maintain the sterility of the circulating fluid during heating and / or cooling processes.

[0100] Figures 12 to 14 Schematic diagrams of other examples of cyclic systems according to this disclosure are shown. Figures 12 to 14 The system shown may include many similar systems to those mentioned above. Figures 1 to 11 The components described are the same components, and similar reference numerals in the figures indicate similar components. Figure 12 System 1020 is shown, including an integrated oxygenator / heat exchanger 100 connected to a fluid volume 302 to be heated. The fluid volume 302 can be any biological or non-biological fluid to be circulated through the oxygenator / heat exchanger 100. The fluid volume 302 is fluidly connected to the oxygenator / heat exchanger 100 via an inlet fluid line 111 and an outlet fluid line 121. Fluid entering the oxygenator / heat exchanger 100 flows through the inlet fluid line 111, and fluid returns to the fluid volume 302 through the outlet fluid line 121. The oxygenator / heat exchanger 100 is then connected to the inlet 214 and outlet 216 of a fluid heating pump assembly 200 via a return fluid line 230 and an outlet fluid line 220, respectively. Therefore, Figure 12 System 1020 is Figure 1 A generalized embodiment of the system 1000, which can be used in any fluid loop to heat biological or non-biological fluids. In some examples, Figure 12 The fluid volume 302 of system 1020 can correspond to Figure 1 The system consists of 1000 patients and 300 patients, in which the circulating fluid is the patients' blood.

[0101] Figure 13 System 1030 is shown, including alternatives Figure 12The oxygenator / heat exchanger 100 shown has a heat exchanger 102. The heat exchanger 102 is not integrally formed with the oxygenator, so oxygenation of the fluid can be performed in a separate component if needed. In some examples, Figure 13 The fluid volume 302 of system 1030 can correspond to Figure 1 The system consists of 1000 patients and 300 patients, in which the circulating fluid is the patients' blood.

[0102] Figure 14 A system 1040 without a heat exchanger and oxygenator is shown. Fluid volume 302 circulates directly through fluid heating pump assembly 200 without using an intermediate heated fluid loop. Specifically, inlet fluid line 111 and outlet fluid line 121 are connected to inlet 214 and outlet 216 of fluid heating pump assembly 200, respectively. Therefore, fluid heating pump assembly 200 directly heats the fluid from fluid volume 302 without using a separate heat exchanger. Figure 14 System 1040 is Figure 2 A generalized embodiment of the cardiac assist system 1010, which can be used in any fluid circuit for heating biological or non-biological fluids. In some examples, Figure 14 The fluid volume 302 of system 1040 can correspond to Figure 2 The system 1010 includes 300 patients, where the circulating fluid is the patient's blood. Since the heating circulation pump only transfers heat during operation, heat transfer to fluids that are easily damaged by overheating (such as blood) can be stopped by stopping the pump.

[0103] While various examples of this disclosure have been provided in the foregoing description, those skilled in the art can make modifications and alterations to these examples without departing from the scope and spirit of this disclosure. For example, it should be understood that features of the various embodiments herein may also be adapted to other embodiments herein. Therefore, the foregoing description is intended to be illustrative rather than restrictive. The disclosure described above is defined by the appended claims, and all changes to the disclosure falling within the meaning and scope of the equivalents of the claims are to be included within its scope.

Claims

1. A heated fluid pump assembly for a fluid flow system, the heated fluid pump assembly comprising: A first component, the first component including an impeller, the impeller being configured to circulate fluid through an impeller chamber; The second component includes a driver for the impeller; as well as An induction heating element, the induction heating element comprising a conductor as part of a first component and an inductor as part of a second component and fluidly isolated from the conductor, The first component can be detached from the second component. The inductor is configured to generate a magnetic field to induce eddy currents in the conductor. The heating element is configured to induce eddy currents in the conductor to heat the conductor, and The conductor is configured to contact the fluid as the fluid circulates through the impeller.

2. The heated fluid pump assembly of claim 1, wherein, The induction heating element includes an inductor coil.

3. The heating fluid pump assembly of claim 2 further includes a controller configured to supply power to the inductor coil to generate the magnetic field.

4. The heating fluid pump assembly according to claim 2, wherein, The inductor coil includes one or more windings.

5. The heating fluid pump assembly according to claim 4, wherein, The one or more windings are arranged in a single layer.

6. The heating fluid pump assembly according to claim 4, wherein, The one or more windings are arranged in multiple layers.

7. The heating fluid pump assembly according to claim 4, wherein, The inductor coil is a printed circuit board.

8. The heating fluid pump assembly according to claim 1, wherein, The conductor is rotatably coupled to the impeller.

9. The heating fluid pump assembly according to claim 1, wherein, The impeller is made entirely of a conductive material, making it a conductor as well.

10. The heating fluid pump assembly according to claim 9, wherein, The conductive impeller includes an arrangement of increased surfaces, thereby increasing the heat exchange area and inducing microturbulence in the fluid.

11. The heating fluid pump assembly according to claim 1, wherein, The conductor is configured as a conductive layer applied to the inner surface of the impeller chamber.

12. The heating fluid pump assembly of claim 11, further comprising a controller configured to provide power to the conductive layer.

13. The heating fluid pump assembly according to claim 1, wherein, The conductor is configured as a fixed heating element attached to the impeller chamber.

14. A heated fluid pump assembly for a fluid flow system, the heated fluid pump assembly comprising: A first component, the first component including an impeller, the impeller being configured to circulate fluid through an impeller chamber; The second component includes a driver for the impeller; as well as An induction heating element, the induction heating element comprising a conductor as part of a first component and a magnet as part of a second component and fluidly isolated from the conductor. The first component can be detached from the second component. The magnet is configured to generate a magnetic field to induce eddy currents in the conductor. The heating element is configured to induce eddy currents in the conductor to heat the conductor, and The conductor is configured to contact the fluid as the fluid circulates through the impeller.

15. The heating fluid pump assembly of claim 14, wherein, The conductor includes lugs extending between the sidewalls of the magnet.

16. The heating fluid pump assembly of claim 15, wherein, The magnet is a permanent magnet.

17. A heated fluid pump assembly for a fluid flow system, the heated fluid pump assembly comprising: A first component, the first component including an impeller, the impeller being configured to circulate fluid through an impeller chamber; The second component includes a driver for the impeller; as well as An electric heating element, the electric heating element comprising a resistor as part of the first component and an electrical energy source as part of the second component, The first component can be detached from the second component. The resistor is electrically connected to the electrical energy source. The electric heating device is configured to heat the resistor, and The resistor is configured to contact the fluid as the fluid circulates through the impeller.

18. The heating fluid pump assembly of claim 17, wherein, The impeller is made entirely of a resistor material, so that the impeller itself is the resistor.

19. The heating fluid pump assembly of claim 18, wherein, The conductive impeller has an arrangement that increases the surface area, thereby increasing the heat exchange area and inducing microturbulence in the fluid.

20. The heating fluid pump assembly of claim 17, wherein, The resistor includes a conductive layer applied to the impeller.

21. The heating fluid pump assembly of claim 17, wherein, The resistor is at least a part of the impeller.

22. The heating fluid pump assembly of claim 17, wherein, The resistor includes a conductive layer applied to the inner surface of the impeller chamber.

23. The heating fluid assembly according to claim 17, wherein, The resistor is electrically connected to the shaft used to rotate the impeller.

24. A heated fluid pump assembly for a fluid flow system, the heated fluid pump assembly comprising: A first component, the first component including an impeller, the impeller being configured to circulate fluid through an impeller chamber; The second component includes an electromagnetic actuator for the impeller; as well as An induction heating element, the induction heating element comprising a conductor as part of the first component and an inductor as part of the second component, The first component can be detached from the second component. The heating element inductor is configured to generate a magnetic field to induce eddy currents in the conductor. The heating element is configured to induce eddy currents in the conductor to heat the conductor. The conductor is configured to contact the fluid as the fluid circulates through the impeller. The impeller includes one or more magnets that interact with a driver of the impeller, and The electromagnetic actuator of the impeller is configured to generate a rotating magnetic field to rotate the impeller by induction.

25. The heating fluid pump assembly of claim 24, wherein, The electromagnetic driver includes a drive coil.

26. The heating fluid pump assembly of claim 25, wherein, The heating element inductor also serves as the induction coil of the electromagnetic driver.

27. The heating fluid pump assembly of claim 25, wherein, The heating element inductor and the electromagnetic driver inductor are separate coils.

28. The heating fluid pump assembly of claim 25, wherein, The heating fluid pump assembly also includes a controller configured to supply power to the heating element inductor coil to generate the magnetic field for heating.

29. The heating fluid pump assembly of claim 25, wherein, The heated fluid pump assembly also includes a controller configured to supply power to the drive coil to generate a rotating magnetic field for rotating the impeller.

30. The heated fluid pump assembly for a fluid flow system according to claim 1, 14, 17 or 24, in, The first component, including an impeller and an impeller chamber, is connected to a heat exchanger via a pipe to form a heated fluid circuit, wherein the heated fluid circuit is configured to circulate heated fluid through the impeller chamber and the heat exchanger.

31. The heated fluid pump assembly for a fluid flow system according to claim 30, wherein, The heating fluid circuit is pre-filled with sterile heating fluid, and the sterile heating fluid circulates through the heat exchanger.

32. The heated fluid pump assembly for a fluid flow system in ECMO applications according to claim 30, in, The initial heating fluid circuit includes the first component comprising an impeller and an impeller chamber, and includes conduits connecting the inlet and outlet of the impeller chamber, the conduits being pre-filled with sterile heating fluid. The initial heating fluid loop is connected to the heat exchanger integrated in the oxygenator under aseptic conditions, such that during ECMO, aseptic heating fluid circulates through the heat exchanger.

33. A heated fluid pump assembly for a fluid flow system according to claim 1, 14, 17 or 24, Including at least one of ECMO machines, cardiopulmonary bypass machines, and dialysis machines. in, The circulating fluid is blood, and The blood is circulated and heated in a circuit, which includes an external portion of the circuit, the patient's circulatory system, and at least one inflow and outflow device connecting the external portion of the circuit to the patient's circulatory system. The external portion of the circuit includes a first component, an oxygenator, and a conduit. The first component includes an impeller and an impeller chamber. The conduit connects the first component to the oxygenator and to the inflow and outflow devices.

34. A heated fluid pump assembly for a fluid flow system according to claim 1, 14, 17 or 24, Including at least one of ECLS machines, heart-lung machines, and dialysis machines. in, The circulating fluid is blood, and The blood is circulated and heated in a circuit, which includes an external portion of the circuit, the patient's circulatory system, and at least one inflow and outflow device connecting the external portion of the circuit to the patient's circulatory system. The external portion of the circuit includes a first component and a conduit. The first component includes an impeller and an impeller chamber. The conduit connects the first component to the inflow and outflow devices.

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