Dental sand blasting powder composition as well as preparation method and application thereof

Abstract

The invention relates to a dental sand blasting powder composition as well as a preparation method and application thereof. The dental sand blasting powder composition comprises biocompatible saccharides, a fluidity regulator, a grinding material, a functional additive and water, the biocompatible saccharides comprise natural disaccharides. The dental sand blasting powder composition provided by the invention is non-irritant to oral soft tissues, can effectively remove stains such as bacterial plaque, soft dirt, smoke stain and tea stain on the surfaces of teeth, forms a protective film on the surfaces of the teeth, reduces tooth sensitivity, and has cleaning and tooth protecting effects.

Description

Technical Field

[0001] This invention relates to the field of dental consumables technology, specifically to a dental air-blasting powder composition, its preparation method, and its uses. Background Technology

[0002] Dental air polishing is a commonly used oral cleaning technique in clinical practice. It uses a high-pressure airflow to spray air polishing powder onto the tooth surface to remove plaque, tartar, and extrinsic stains. Therefore, air polishing powder is an important consumable for air polishing.

[0003] Existing blasting powders are mainly based on materials such as sodium bicarbonate, glycine, or erythritol, but they have significant drawbacks. Sodium bicarbonate has strong cleaning power but is highly irritating, easily damaging gums and restorations, and has a poor taste. Although some commercially available products mask the salty taste of sodium bicarbonate by adding sugar or saccharin salt to improve the taste, these products are cariogenic. Glycine-based blasting powder has lower hardness and a slightly sweet taste, making it more comfortable for patients, but its cleaning efficiency is low and it cannot effectively remove tobacco stains and pigments. Erythritol is expensive, hygroscopic, and has poor storage stability.

[0004] For example, CN114617791A discloses a dental blasting powder composition, including glycyrrhizate, sodium bicarbonate, glycine or erythritol, and also includes additives such as silica (micronized powder), bleaching agents, analgesics, bactericides and flavoring additives. This dental blasting powder composition still cannot solve the problems of sodium bicarbonate being highly irritating, having unstable storage, and being unsuitable for sensitive populations.

[0005] Therefore, with the increasing demand for oral health, especially for sensitive individuals and those wearing prostheses, there is an urgent need for a sandblasting powder that combines cleaning power, gentleness, and safety. Summary of the Invention

[0006] To address the above problems, the present invention aims to provide a dental air-blasting powder composition, its preparation method, and its uses.

[0007] To achieve this objective, the present invention adopts the following technical solution:

[0008] In a first aspect, the present invention provides a dental blasting powder composition comprising biocompatible sugars, flow modifiers, abrasives, functional additives, and water;

[0009] The biocompatible sugars include natural disaccharides.

[0010] The dental air polishing powder composition provided by this invention addresses the problems of strong irritation, conflict between cleaning and tooth protection, and poor storage stability of existing air polishing powders. By adding natural disaccharides, flowability regulators, abrasives, functional additives, and water, it can control the air polishing hardness to a moderate level, avoiding damage to tooth enamel, gums, and restorations. It is biocompatible and has low sensitivity, making it suitable for sensitive individuals and restoration wearers.

[0011] Preferably, the biocompatible sugar includes trehalose.

[0012] It should be noted that this invention specifically uses trehalose in combination with other components to form a dental blasting powder composition. With trehalose as the core base material, it exhibits high biocompatibility, meets ISO 10993 standards, is non-irritating to oral soft tissues, and is gentle and hypoallergenic, effectively preventing damage to soft tissues such as the gums. Simultaneously, it provides a gentle blasting action, synergistically enhancing the cleaning power of the blasting powder with abrasives, effectively removing plaque, soft deposits, tobacco stains, tea stains, and other stains from the tooth surface. Furthermore, trehalose can form a protective film on the tooth surface, reducing tooth sensitivity and achieving both cleaning and dental protection effects.

[0013] Preferably, the average particle size of the biocompatible sugar is 10-120 μm, for example, it can be 10 μm, 15 μm, 20 μm, 25 μm, 30 μm, 35 μm, 40 μm, 45 μm, 50 μm, 55 μm, 60 μm, 70 μm, 80 μm, 90 μm, 100 μm, 110 μm or 120 μm, but is not limited to the listed values, and other unlisted values ​​within the range are also applicable.

[0014] In this invention, by controlling the average particle size of biocompatible sugars, effective abrasive force can be generated without damaging tooth enamel. Simultaneously, improved flowability allows for compatibility with existing medical blasting equipment, preventing clogging or uneven spraying. This facilitates subsequent removal by airflow or cleaning fluid, with a residue rate controlled to ≤0.1%, meeting the requirements for residue-free medical applications. When the particle size is too large, it becomes excessively irritating, easily scratching tooth enamel, and has poor flowability, easily agglomerating and clogging the blasting equipment, increasing the risk of residue. When the particle size is too small, cleaning efficiency is insufficient, increasing the risk of inhalation or diffusion. Excessively small particles are prone to agglomeration due to van der Waals forces, which reduces stability during use.

[0015] Preferably, the purity of the biocompatible sugar is ≥95%, for example, it can be 95%, 96%, 97%, 98% or 99%, but is not limited to the listed values. Other unlisted values ​​within the range are also applicable.

[0016] Preferably, the biocompatible sugars have a rounded or blunt shape.

[0017] Preferably, the flowability modifier comprises silica powder and / or food-grade talc.

[0018] In this invention, the flowability modifiers silica powder and / or talc powder can resist moisture absorption, extend the shelf life of the dental air-blasting powder composition, and improve storage stability.

[0019] Preferably, the average particle size of the flowability regulator is 10-200 nm, for example, it can be 10 nm, 20 nm, 30 nm, 40 nm, 50 nm, 60 nm, 70 nm, 80 nm, 90 nm, 100 nm, 110 nm, 120 nm, 130 nm, 140 nm, 150 nm, 160 nm, 170 nm, 180 nm or 200 nm, but is not limited to the listed values, and other unlisted values ​​within the range are also applicable.

[0020] Preferably, the abrasive comprises hydroxyapatite and / or calcium carbonate.

[0021] Preferably, the average particle size of the hydroxyapatite is 0.02-45 μm, for example, it can be 0.02 μm, 2 μm, 5 μm, 10 μm, 15 μm, 20 μm, 25 μm, 30 μm, 35 μm, 40 μm or 45 μm, but is not limited to the listed values, and other unlisted values ​​within the range are also applicable.

[0022] Preferably, the average particle size of the calcium carbonate is 0.02-45 μm, for example, it can be 0.02 μm, 2 μm, 5 μm, 10 μm, 15 μm, 20 μm, 25 μm, 30 μm, 35 μm, 40 μm or 45 μm, but is not limited to the listed values, and other unlisted values ​​within the range are also applicable.

[0023] Preferably, the abrasive has a Mohs hardness of 3-5, for example, 3, 3.2, 3.4, 3.6, 3.8, 4, 4.2, 4.4, 4.6, 4.8 or 5, but is not limited to the listed values. Other unlisted values ​​within the range are also applicable.

[0024] Preferably, the functional additive includes any one or a combination of at least two of dipotassium glycyrrhizate, menthol, or fluorides.

[0025] Preferably, the fluoride includes any one or a combination of at least two of sodium fluoride, stannous fluoride, sodium monofluorophosphate, or calcium fluoride.

[0026] Preferably, the weight percentage of fluorine in the dental blasting powder composition is 0.05-0.1%, for example, it can be 0.05%, 0.06%, 0.07%, 0.08%, 0.09% or 0.1%, but is not limited to the listed values. Other unlisted values ​​within the range are also applicable.

[0027] In this invention, the fluoride element in the dental air polishing powder composition can form a fluorapatite protective layer on the tooth surface, enhance the acid resistance of tooth enamel, help prevent tooth decay, and form a synergistic effect with the periodontal care and whitening functions of the dental air polishing powder composition; at the same time, it avoids the risk of enamel fluorosis caused by excessive fluoride content.

[0028] Preferably, the dental blasting powder composition comprises, by weight percentage: 60-99% biocompatible sugars, 0.1-3% flow modifiers, 0.1-5% abrasives, 0.1-5% functional additives, and the balance being water.

[0029] In this invention, the weight percentage of biocompatible sugars is 60-99%, for example, it can be 60%, 62%, 64%, 66%, 68%, 70%, 72%, 74%, 76%, 78%, 80%, 82%, 84%, 85%, 90%, 95%, or 99%; the weight percentage of flowability regulators is 0.1-3%, for example, it can be 0.1%, 0.5%, 1%, 1.5%, 2%, 2.5%, or 3%; the weight percentage of abrasives is 0.1-5%, for example, it can be 0.1%, 0.5%, 1%, 1.5%, 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, or 5%; and the weight percentage of functional additives is 0.1-5%, for example, it can be 0.1%, 0.5%, 1%, 1.5%, 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, or 5%, but is not limited to the listed values. Other unlisted values ​​within the range are also applicable.

[0030] It should be noted that the trehalose content can be adjusted according to cleaning needs and comfort requirements to suit different scenarios: For high-cleaning scenarios (such as removing stubborn tobacco stains and tea stains), a formula with 60-65% trehalose by weight is recommended to effectively remove stubborn stains; for high-comfort scenarios (such as children and people with sensitive gums), a formula with 75-80% trehalose by weight is recommended to be gentle and non-irritating, avoiding damage to gums and tooth enamel; for general scenarios (routine teeth cleaning), a formula with 68-72% trehalose by weight is recommended to balance cleaning effectiveness and user comfort.

[0031] In a second aspect, the present invention provides a method for preparing a dental air-blasting powder composition as described in the first aspect of the present invention, the preparation method comprising the following steps:

[0032] The raw materials are mixed according to the composition of the dental blasting powder composition, and then successively molded, sieved, sterilized and sealed to obtain the dental blasting powder composition.

[0033] The preparation method provided by this invention employs steps such as mixing, molding, sieving, drying, sterilization, and sealing packaging to obtain a dental sandblasting powder composition, which is compatible with existing production processes and easy to industrialize.

[0034] Preferably, the raw materials, including biocompatible sugars, flow modifiers, abrasives and functional additives, are dried before mixing, and then the dried raw materials are mixed with water and then shaped.

[0035] Preferably, the drying temperature is 80-100℃, for example, it can be 80℃, 82℃, 84℃, 86℃, 88℃, 90℃, 92℃, 94℃, 96℃, 98℃ or 100℃, but is not limited to the listed values, and other unlisted values ​​within the range are also applicable.

[0036] Preferably, the drying time is 2-4 hours, for example, 2 hours, 2.5 hours, 3 hours, 3.5 hours or 4 hours, but not limited to the listed values. Other unlisted values ​​within the range are also applicable.

[0037] Preferably, the water content in the dried raw material is ≤0.5% by weight, for example, it can be 0.5%, 0.4%, 0.3%, 0.2% or 0.1%, but is not limited to the listed values. Other unlisted values ​​within the range are also applicable.

[0038] Preferably, the mixing speed is 100-200 r / min, for example, it can be 100 r / min, 120 r / min, 140 r / min, 160 r / min, 180 r / min or 200 r / min, but is not limited to the listed values, and other unlisted values ​​within the range are also applicable.

[0039] Preferably, the mixing time is 30-60 minutes, for example, 30 minutes, 35 minutes, 40 minutes, 45 minutes, 50 minutes, 55 minutes or 60 minutes, but not limited to the listed values. Other unlisted values ​​within the range are also applicable.

[0040] Preferably, the molding method includes granulation or crushing.

[0041] Preferably, the granulation method includes spray drying.

[0042] It should be noted that the granulation method described in this invention can adopt common methods in the art, including but not limited to spray drying, fluidized bed granulation, high-speed shear granulation, etc. Spray drying is preferred, as it is more compatible with existing production lines and easier to industrialize.

[0043] Preferably, the inlet air temperature for spray drying is 120-150℃, for example, it can be 120℃, 125℃, 130℃, 135℃, 140℃, 145℃ or 150℃, but is not limited to the listed values, and other unlisted values ​​within the range are also applicable.

[0044] Preferably, the outlet air temperature of the spray dryer is 60-80℃, for example, it can be 60℃, 62℃, 65℃, 68℃, 70℃, 72℃, 75℃, 78℃ or 80℃, but is not limited to the listed values. Other unlisted values ​​within the range are also applicable.

[0045] Preferably, the atomization pressure of the spray drying is 0.2-0.4 MPa, for example, it can be 0.2 MPa, 0.22 MPa, 0.24 MPa, 0.26 MPa, 0.28 MPa, 0.3 MPa, 0.32 MPa, 0.34 MPa, 0.36 MPa, 0.38 MPa or 0.4 MPa, but is not limited to the listed values. Other unlisted values ​​within the range are also applicable.

[0046] Preferably, the particle size after sieving is 10-120 μm, for example, it can be 10 μm, 20 μm, 30 μm, 40 μm, 50 μm, 60 μm, 70 μm, 80 μm, 90 μm, 100 μm, 110 μm or 120 μm, but is not limited to the listed values, and other unlisted values ​​within the range are also applicable.

[0047] Preferably, the sterilization method includes microwave sterilization.

[0048] Preferably, the sterilization temperature is 50-134℃, for example, it can be 50℃, 60℃, 70℃, 80℃, 90℃, 100℃, 110℃, 120℃, 130℃ or 134℃, but is not limited to the listed values, and other unlisted values ​​within the range are also applicable.

[0049] Preferably, the sterilization time is 3-60 min, for example, it can be 3 min, 5 min, 8 min, 10 min, 20 min, 30 min, 40 min, 50 min or 60 min, but is not limited to the listed values. Other unlisted values ​​within the range are also applicable.

[0050] As a preferred embodiment of the second aspect of the present invention, the preparation method includes the following steps:

[0051] Raw materials containing biocompatible sugars, flow modifiers, abrasives, and functional additives are dried at 80-100℃ for 2-4 hours, with the water content in the dried raw materials being ≤0.5% by weight. Water is then added and mixed at 100-200 r / min for 30-60 minutes. Spray drying is then carried out at an inlet air temperature of 120-150℃, an outlet air temperature of 60-80℃, and an atomization pressure of 0.2-0.4 MPa to granulate the material. The granules are then sieved to a particle size of 10-120 μm and dried. Finally, the material is microwave sterilized at 50-134℃ for 3-60 minutes and then sealed and packaged to obtain the dental blasting powder composition.

[0052] Thirdly, the present invention provides the use of the dental blasting powder composition as described in the first aspect of the present invention for dental cleaning.

[0053] In this invention, the dental air-blasting powder composition is used for dental cleaning. It can gently and effectively remove stains such as plaque, soft deposits, tobacco stains, and tea stains from the tooth surface. It can form a protective film on the tooth surface, reduce tooth sensitivity, and is suitable for sensitive people and those wearing restorations.

[0054] Preferably, the dental cleaning includes any one or a combination of at least two of supragingival cleaning, subgingival cleaning, or periprosthetic cleaning.

[0055] It should be noted that the dental air-blasting powder composition provided by this invention not only has cleaning and care effects during the air-blasting teeth cleaning process, but can also be further used to prepare compositions for preventing periodontal disease, compositions for preventing tooth decay, drugs for periodontitis, and compositions for teeth whitening, showing broad prospects in multiple dental fields. The composite phase structure formed by trehalose and hydroxyapatite in the dental air-blasting powder composition of this invention has significant antibacterial activity, with an inhibition rate of ≥90% against periodontal pathogens (such as Porphyromonas gingivalis and Actinobacillus actinomycetii). It can effectively reduce the colonization of harmful bacteria in periodontal pockets, while thoroughly removing plaque and soft deposits from areas difficult to reach with a toothbrush, such as the interproximal surfaces and edges of periodontal pockets, preventing plaque mineralization into tartar, and reducing the risk of periodontal disease from the source. For patients with mild to moderate periodontitis, the gentle air-blasting action can clean residual inflammatory exudate and necrotic tissue in the periodontal pockets, and the biocompatibility of trehalose can reduce irritation to inflamed gingival tissue, creating a favorable environment for periodontal tissue repair. In addition, the trehalose and abrasive in the dental blasting powder composition of the present invention work synergistically to physically remove extrinsic pigments (stains from tobacco, tea, coffee, etc.) from the tooth surface, with a pigment removal rate of ≥95%. At the same time, the natural hydrophilicity of trehalose can improve the compatibility of the dental blasting powder composition with the water medium, reduce pigment residue and re-adhesion during the grinding process, and avoid excessive abrasion of tooth enamel by traditional whitening blasting powders, thus achieving gentle whitening.

[0056] Preferably, the air pressure of the dental abrasive powder composition used for dental cleaning is 0.1-0.5 MPa, for example, 0.1 MPa, 0.15 MPa, 0.2 MPa, 0.25 MPa, 0.3 MPa, 0.4 MPa or 0.5 MPa, but is not limited to the listed values. Other unlisted values ​​within the range are also applicable.

[0057] Preferably, the abrasive spraying distance of the dental abrasive powder composition when used for dental cleaning is 1-10 mm, for example, it can be 1 mm, 3 mm, 3.5 mm, 4 mm, 4.5 mm, 5 mm, 6 mm, 8 mm or 10 mm, but is not limited to the listed values, and other unlisted values ​​within the range are also applicable.

[0058] Compared with the prior art, the present invention has the following beneficial effects:

[0059] (1) The dental air polishing powder composition provided by the present invention is compounded by natural disaccharides, flowability regulators, abrasives, functional additives and water, which can control the air polishing hardness to a moderate level, avoid damage to tooth enamel, gums and restorations, and has biocompatibility and low sensitivity, making it suitable for sensitive people and restoration wearers. In addition, it has good storage stability, moisture absorption rate ≤2.5%, and shelf life ≥2 years.

[0060] (2) The dental blasting powder composition provided by the present invention preferably uses trehalose as the core base material, which has high biocompatibility, meets the ISO10993 standard, and is non-irritating to oral soft tissues. At the same time, it can exert a gentle blasting effect, synergistically enhance the cleaning power of the blasting powder with the abrasive, and effectively remove plaque, soft deposits, tobacco stains, tea stains and other stains on the tooth surface. Under optimal conditions, the plaque removal rate is ≥91%. In addition, trehalose can also form a protective film on the tooth surface, reduce tooth sensitivity, and take into account both cleaning and tooth protection effects.

[0061] (3) The preparation method of the dental sandblasting powder composition provided by the present invention is simple and easy to industrialize. Detailed Implementation

[0062] The technical solution of the present invention will be further illustrated below through specific embodiments. Those skilled in the art should understand that the embodiments described are merely illustrative of the present invention and should not be construed as limiting the invention in any way.

[0063] The numerical range described in this invention includes not only the point values ​​listed above, but also any point values ​​within the numerical ranges not listed above. Due to space limitations and for the sake of brevity, this invention will not exhaustively list all the specific point values ​​included in the range.

[0064] Example 1

[0065] This embodiment provides a dental blasting powder composition, which, by weight percentage, comprises: 78% trehalose, 2% silica powder, 1% hydroxyapatite, 1% dipotassium glycyrrhizate, 1% menthol, 0.13% sodium fluoride, and the balance being water.

[0066] The trehalose has an average particle size of 35 μm, a purity of 99.5%, and a rounded shape. The silica powder has an average particle size of 100 nm, and the hydroxyapatite has an average particle size of 20 μm.

[0067] The present invention also provides a method for preparing the above-mentioned dental air-blasting powder composition, the method comprising the following steps:

[0068] Raw materials containing trehalose, silica powder, hydroxyapatite, dipotassium glycyrrhizate, menthol, and sodium fluoride were dried at 90°C for 3 hours. The water content in the dried raw materials was ≤0.5% by weight. Water was then added and mixed at 150 r / min for 45 minutes. Spray drying was then carried out at an inlet air temperature of 135°C, an outlet air temperature of 70°C, and an atomization pressure of 0.3 MPa to granulate the material. The granules were then sieved to a particle size of 10-120 μm and dried. Finally, the mixture was microwave sterilized at 110°C for 12 minutes and then sealed and packaged to obtain the dental sandblasting powder composition.

[0069] This embodiment also provides a use of the above-described dental abrasive powder composition for dental cleaning.

[0070] The dental air-blasting powder composition obtained in this embodiment has good storage stability, with a moisture absorption rate of ≤2.5% and a shelf life of ≥2 years.

[0071] Example 2

[0072] This embodiment provides a dental blasting powder composition, which, by weight percentage, comprises: 85% trehalose, 3% food-grade talc, 3% calcium carbonate, 0.4% dipotassium glycyrrhizate, 0.4% menthol, 0.2% sodium fluoride, and the balance being water.

[0073] The trehalose has an average particle size of 10 μm, a purity of 99.5%, and a rounded shape. The food-grade talc has an average particle size of 10 nm, and the calcium carbonate has an average particle size of 1 μm.

[0074] The present invention also provides a method for preparing the above-mentioned dental air-blasting powder composition, the method comprising the following steps:

[0075] Raw materials containing trehalose, food-grade talc, calcium carbonate, dipotassium glycyrrhizate, menthol, and sodium fluoride were dried at 80°C for 4 hours. The water content in the dried raw materials was ≤0.5% by weight. Water was then added and mixed at 100 r / min for 60 minutes. Spray drying was then carried out at an inlet air temperature of 120°C, an outlet air temperature of 80°C, and an atomization pressure of 0.2 MPa to granulate the mixture. The granules were then sieved to a particle size of 10-120 μm and dried. Finally, the mixture was microwave sterilized at 120°C for 5 minutes and then sealed and packaged to obtain the dental sandblasting powder composition.

[0076] This embodiment also provides a use of the above-described dental abrasive powder composition for dental cleaning.

[0077] The dental air-blasting powder composition obtained in this embodiment has good storage stability, with a moisture absorption rate of ≤2.5% and a shelf life of ≥2 years.

[0078] Example 3

[0079] This embodiment provides a dental blasting powder composition, which, by weight percentage, comprises: 60% trehalose, 1% silica powder, 1% hydroxyapatite, 2% dipotassium glycyrrhizate, 2% menthol, 0.15% calcium fluoride, and the balance being water.

[0080] The trehalose has an average particle size of 60 μm, a purity of 99.5%, and a rounded shape. The silica powder has an average particle size of 200 nm, and the hydroxyapatite has an average particle size of 45 μm.

[0081] The present invention also provides a method for preparing the above-mentioned dental air-blasting powder composition, the method comprising the following steps:

[0082] Raw materials containing trehalose, silica powder, hydroxyapatite, dipotassium glycyrrhizate, menthol, and calcium fluoride were dried at 100°C for 2 hours. The water content in the dried raw materials was ≤0.5% by weight. Water was then added and mixed at 200 r / min for 30 minutes. Spray drying was then carried out at an inlet air temperature of 150°C, an outlet air temperature of 60°C, and an atomization pressure of 0.4 MPa to granulate the material. The granules were then sieved to a particle size of 10-120 μm and dried. Finally, the mixture was microwave sterilized at 100°C for 20 minutes and then sealed and packaged to obtain the dental sandblasting powder composition.

[0083] This embodiment also provides a use of the above-described dental abrasive powder composition for dental cleaning.

[0084] The dental air-blasting powder composition obtained in this embodiment has good storage stability, with a moisture absorption rate of ≤2.5% and a shelf life of ≥2 years.

[0085] Example 4

[0086] This embodiment provides a dental abrasive powder composition, which differs from Example 1 only in that the average particle size of trehalose is 5 μm.

[0087] Example 5

[0088] This embodiment provides a dental air-blasting powder composition, which differs from Example 1 only in that the average particle size of trehalose is 150 μm.

[0089] Comparative Example 1

[0090] This comparative example provides a dental air-blasting powder composition, which differs from Example 1 only in that trehalose is not added, but is replaced with an equal weight percentage of hydroxyapatite.

[0091] Comparative Example 2

[0092] This comparative example provides a dental air-blasting powder composition, which differs from Example 1 only in that hydroxyapatite is not added, but is replaced with an equal weight percentage of trehalose.

[0093] Performance testing: The dental blasting powder compositions provided in the above embodiments and comparative examples were used to test the plaque removal rate. Plaque indicator was applied to the tooth surface, and blasting was performed for 20 seconds at a blasting distance of 5 mm and an air pressure of 0.3 MPa. The plaque removal rate was calculated, and the results are shown in Table 1.

[0094] Table 1

[0095]

[0096] As can be seen from the data in Table 1:

[0097] (1) As can be seen from the data of Examples 1-3, under better conditions, the dental sandblasting powder composition provided by the present invention can achieve a high cleaning effect and the plaque removal rate reaches more than 91%.

[0098] (2) A comprehensive comparison of the data from Examples 1 and 4-5 shows that the present invention can further improve the removal rate of dental plaque by further optimizing and controlling the average particle size of trehalose. In Example 4, the average particle size of trehalose was too small, resulting in insufficient cleaning efficiency and a risk of inhalation or diffusion. In Example 5, although the cleaning effect was slightly increased, it was too irritating, easily scratching the enamel, and had poor fluidity, easily agglomerating and clogging the sandblasting equipment, increasing the risk of residue.

[0099] (3) Comparing the data of Example 1 and Comparative Examples 1-2, it can be seen that the present invention uses trehalose and abrasive to achieve synergistic effect. Compared with using only trehalose or abrasive, it can not only improve the removal rate of dental plaque, but also reduce irritation, ensure gentle cleaning, and take into account both cleaning and tooth protection.

[0100] In summary, the dental air-blasting powder composition provided by this invention is non-irritating to oral soft tissues, effectively removes plaque, soft deposits, tobacco stains, tea stains and other stains from the tooth surface, and forms a protective film on the tooth surface to reduce tooth sensitivity, thus achieving both cleaning and tooth protection effects.

[0101] The above description is only a specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Those skilled in the art should understand that any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in the present invention fall within the protection and disclosure scope of the present invention.

Claims

1. A dental air-blasting powder composition, characterized in that, The dental blasting powder composition includes biocompatible sugars, flow modifiers, abrasives, functional additives, and water; The biocompatible sugars include natural disaccharides.

2. The dental blasting powder composition according to claim 1, characterized in that, The biocompatible sugars include trehalose; Preferably, the average particle size of the biocompatible sugars is 10-120 μm; Preferably, the purity of the biocompatible sugars is ≥95%; Preferably, the shape of the biocompatible sugar includes a rounded or blunt shape; Preferably, the flowability modifier comprises silica powder and / or food-grade talc; Preferably, the flowability modifier has an average particle size of 10-200 nm.

3. The dental air-blasting powder composition according to claim 1 or 2, characterized in that, The abrasive includes hydroxyapatite and / or calcium carbonate; Preferably, the average particle size of the hydroxyapatite is 0.02-45 μm; Preferably, the average particle size of the calcium carbonate is 0.02-45 μm; Preferably, the abrasive has a Mohs hardness of 3-5; Preferably, the functional additive includes any one or a combination of at least two of dipotassium glycyrrhizate, menthol, or fluorides; Preferably, the fluoride includes any one or a combination of at least two of sodium fluoride, stannous fluoride, sodium monofluorophosphate, or calcium fluoride; Preferably, the fluorine content in the dental blasting powder composition is 0.05-0.1% by weight.

4. The dental air-blasting powder composition according to any one of claims 1-3, characterized in that, The dental blasting powder composition comprises, by weight percentage: 60-99% biocompatible sugars, 0.1-3% flow modifiers, 0.1-5% abrasives, 0.1-5% functional additives, and the balance being water.

5. A method for preparing the dental air-blasting powder composition according to any one of claims 1-4, characterized in that, The preparation method includes the following steps: The raw materials are mixed according to the composition of the dental blasting powder composition, and then successively molded, sieved, dried, sterilized and sealed in packaging to obtain the dental blasting powder composition.

6. The preparation method according to claim 5, characterized in that, Before mixing, the raw materials, including biocompatible sugars, flow modifiers, abrasives and functional additives, are dried, and then the dried raw materials are mixed with water and then shaped. Preferably, the drying temperature is 80-100℃; Preferably, the drying time is 2-4 hours; Preferably, the water content in the dried raw material is ≤0.5% by weight; Preferably, the mixing speed is 100-200 r / min; Preferably, the mixing time is 30-60 minutes.

7. The preparation method according to claim 5 or 6, characterized in that, The molding method includes granulation or crushing; Preferably, the granulation method includes spray drying; Preferably, the inlet air temperature for the spray drying is 120-150°C; Preferably, the outlet air temperature of the spray dryer is 60-80℃; Preferably, the atomization pressure of the spray drying is 0.2-0.4 MPa; Preferably, the particle size after sieving is 10-120 μm.

8. The preparation method according to any one of claims 5-7, characterized in that, The sterilization method includes microwave sterilization; Preferably, the sterilization temperature is 50-134℃; Preferably, the sterilization time is 3-60 minutes.

9. Use of the dental air-blasting powder composition according to any one of claims 1-4, characterized in that, The dental abrasive powder composition is used for dental cleaning.

10. The use according to claim 9, characterized in that, The dental cleaning includes any one or a combination of at least two of supragingival cleaning, subgingival cleaning, or periprosthetic cleaning. Preferably, the air pressure when the dental abrasive powder composition is used for dental cleaning is 0.1-0.5 MPa; Preferably, the abrasive spraying distance of the dental abrasive powder composition when used for dental cleaning is 1-10 mm.

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