Flux and energy spectrum synergistic regulation device, method and system for boron neutron capture therapy

By using an independently movable composite modulation rod array and beam monitoring system in the BNCT device, the two-dimensional spatial flux and energy spectrum characteristics of the neutron beam were synchronously controlled, solving the problem that the flux intensity and energy spectrum could not be independently controlled in the existing technology, and improving the accuracy and personalization of BNCT treatment.

CN121754820BActive Publication Date: 2026-07-03LANZHOU UNIV +1

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
LANZHOU UNIV
Filing Date
2026-03-03
Publication Date
2026-07-03

AI Technical Summary

Technical Problem

Existing BNCT devices struggle to independently control neutron flux intensity while adjusting the local energy spectrum, making it difficult to precisely match irregular and non-uniform three-dimensional tumor shapes. In particular, they cannot ensure dual optimization of the tumor's dose and energy spectrum while protecting adjacent dangerous organs.

Method used

An array of composite modulation rods capable of independent linear motion is employed, with each rod consisting of segments made of two different neutronics materials. Combined with a drive and position sensing system and a beam monitoring unit, the synchronous, independent, and dynamic control of the two-dimensional spatial flux distribution and energy spectrum characteristics of the neutron beam is achieved.

Benefits of technology

It achieves precise modulation of the flux intensity and energy spectrum characteristics of neutron beams in local regions of two-dimensional space, which can be adapted to complex three-dimensional tumor target areas, protect organs at risk, and dynamically adjust local neutron energy, thereby improving the personalization level and potential efficacy of BNCT treatment.

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Abstract

This invention discloses a device, method, and system for synergistic regulation of flux and energy spectrum in boron neutron capture therapy (BNCT), belonging to the field of radiotherapy technology. It includes a composite modulation unit array, comprising multiple composite modulation rods capable of independent linear motion along a direction parallel to the beam axis. Each composite modulation rod is composed of at least two segments of neutronic materials with different neutron reaction cross sections and moderation capabilities, fixedly connected along its direction of motion. By employing an array of independently linearly moving composite modulation rods, and ensuring that each rod is composed of at least two different neutronic material segments, this invention breaks the traditional paradigm of separating flux regulation and energy spectrum regulation. It achieves synchronous, independent, and dynamic integrated modulation of the flux intensity and energy spectrum characteristics of the output neutron beam in any local region of two-dimensional space, thereby achieving dual optimization of dose and biological effects, significantly improving the personalization level and potential efficacy of BNCT treatment.
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