Medicine for treating liver cirrhosis and liver cancer
By using a specific combination of traditional Chinese medicine to treat cirrhosis and liver cancer, the problem of long treatment cycles and poor efficacy has been solved. This approach enables targeted and personalized treatment, thereby improving the overall treatment outcome for cirrhosis and liver cancer.
Patent Information
- Application Number
- CN202411571582.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-06
- Publication Date
- 2026-04-03
AI Technical Summary
Existing Chinese medicine prescriptions for treating cirrhosis and liver cancer have long treatment cycles and poor effects, especially when facing complex liver disease symptoms such as liver qi stagnation, liver and kidney yin deficiency, or spleen and kidney yang deficiency, they lack targeted treatment.
A specific combination of traditional Chinese medicines, including ginseng, red and white peony root, rose, chrysanthemum, and prepared rehmannia root, combined with honeysuckle, mulberry leaf, artemisia capillaris, and gentian root, is used to treat cirrhosis and liver cancer. Bupleurum and wolfberry are added to regulate the immune system and improve liver function for different symptoms.
By treating the symptoms, the treatment cycle is shortened, the treatment effect is improved, dependence on anti-inflammatory drugs is reduced, liver function is improved, and personalized treatment is provided for different liver disease symptoms.
Abstract
Description
Technical Field
[0001] This invention relates to the field of pharmaceutical formulations for treating liver diseases, specifically drugs for treating cirrhosis and liver cancer. Background Technology
[0002] Traditional Chinese medicine (TCM) refers to drugs collected, processed, and prepared under the guidance of traditional Chinese medical theories, explaining their mechanisms of action and guiding clinical application. TCM primarily originates from natural medicines and their processed products, including plant-based, animal-based, and mineral-based drugs, as well as some chemical and biological products. Because TCM is predominantly plant-based, there is a saying that "all medicines are based on herbs." Currently available TCM formulas for treating cirrhosis and liver cancer are relatively common and can effectively serve as adjunctive therapy. Due to their mild nature and significant adjunctive therapeutic effects, these formulas are typically taken long-term. However, in reality, liver disease is never an isolated condition and is complex. While common TCM formulas can effectively assist in the treatment of cirrhosis and liver cancer, and are mild in nature, requiring long-term use, liver disease is often accompanied by liver qi stagnation, liver and kidney yin deficiency, or spleen and kidney yang deficiency. If these underlying problems are not addressed with targeted treatment, the treatment cycle for cirrhosis and liver cancer may be prolonged, and the treatment effect may be poor. Summary of the Invention
[0003] This invention provides a drug for treating cirrhosis and liver cancer, mainly for oral administration in patients with cirrhosis and liver cancer, addressing the problems of longer treatment cycles and poor treatment effects in existing treatments for cirrhosis and liver cancer.
[0004] To achieve the above objectives, the present invention provides the following technical solution: a drug for treating cirrhosis and liver cancer, comprising the following raw materials in the following weight ratio: Codonopsis pilosula 15-30g, Paeonia lactiflora (red and white) 10-30g, Rosa rugosa 3-10g, Chrysanthemum morifolium 3-10g, Rehmannia glutinosa (processed) 6-15g, Lonicera japonica 5-10g, Morus alba leaf 5-10g, Artemisia capillaris 5-10g, Gentiana scabra 5-10g, Poria cocos 5-10g, Astragalus membranaceus 5-20g, Curcuma longa 4-12g, Angelica sinensis 5-15g, Atractylodes macrocephala 5g. -12, Polygonatum 10-18, Isatis root 7-15, Crataegus pinnatifida 15-30, Schisandra chinensis 4-12, Rosin 1-5, Frankincense 2-10, Deer antler glue 3-15, Eucommia ulmoides 10-20, Ephedra sinica 1-8, Aconitum carmichaelii 1-8, Glycyrrhiza uralensis 2-30, Dioscorea opposita 8-50, Gentiana macrophylla 5-10, Artemisia capillaris 9-15, Sophora flavescens 5-30, Bletilla striata 5-10, Commiphora myrrha 3-9, Carrot 10-25, Acanthopanax senticosus 6-12, Drynaria fortunei 6-15.
[0005] Preferably, the weight ratio of the raw materials also includes Bupleurum chinense 10-20, Citrus reticulata peel 10-15, Aucklandia lappa 4-15, Cyperus rotundus 6-15, Citrus medica 9-15, Paeonia lactiflora 9-15, Salvia miltiorrhiza 10-15, Typha orientalis pollen 4-10, Prunus persica kernel 10-20, Carthamus tinctorius 2-10, and Trionyx sinensis shell 12-25.
[0006] Preferably, the weight ratio of the raw materials may further include 6-15g of wolfberry, 8-15g of privet fruit, 10-15g of eclipta prostrata, 10-25g of mulberry, 5-15g of dodder seed, 5-15g of ophiopogon japonicus, and 12-20g of rehmannia root.
[0007] Preferably, the weight ratio of the raw materials may include 9-18 parts Epimedium, 4-10 parts Curculigo orchioides, 3-10 parts Psoralea corylifolia, and 8-15 parts Myristica fragrans.
[0008] This invention provides a drug for treating cirrhosis and liver cancer, which has the following beneficial effects:
[0009] 1. This prescription adds the following to existing formulas for treating cirrhosis and liver cancer:
[0010] Honeysuckle: This herb has the effect of clearing heat and detoxifying, and can help treat symptoms of liver diseases such as hepatitis and jaundice;
[0011] Add mulberry leaves: Mulberry leaves are an herb that can help lower liver enzyme levels and may help treat cirrhosis.
[0012] Add Artemisia capillaris: This is a traditional Chinese medicine that can clear heat and detoxify, and can also treat symptoms of liver diseases such as hepatitis and jaundice;
[0013] Add gentian: This herb can increase bile secretion, aid digestion and excretion, and also improve liver function;
[0014] Add Poria cocos: Poria cocos is an herb that can help the liver detoxify and is often used to treat liver diseases such as cirrhosis.
[0015] Adding the above-mentioned medicinal materials can make the prescription effective in treating hepatitis symptoms caused by cirrhosis and liver cancer, reducing patients' dependence on anti-inflammatory drugs. When used in combination with astragalus, it can regulate the immune system and improve liver function.
[0016] 2. Depending on the patient's specific liver disease symptoms, adjuvant medications can be added to the prescription. Adding Bupleurum, Tangerine Peel, Costus Root, Cyperus Rhizome, Buddha's Hand, White Peony Root, Salvia Root, Typha Pollen, Peach Kernel, Safflower, and Turtle Shell to the prescription can treat symptoms of liver qi stagnation and blood stasis. Adding Lycium Fruit, Ligustrum Lucidum, Eclipta Prostrata, Mulberry Fruit, Cuscuta Seed, Ophiopogon Root, and Rehmannia Root can treat liver and kidney yin deficiency. Adding Epimedium, Curculigo Rhizome, Psoralea Fruit, and Nutmeg can treat spleen and kidney yang deficiency. By prescribing medications tailored to the specific symptoms, the treatment of the patient can be strengthened. Detailed Implementation
[0017] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.
[0018] This invention provides a technical solution: a drug for treating cirrhosis and liver cancer, comprising the following raw materials in the following weight ratio: Codonopsis pilosula 15-30g, Paeonia lactiflora (red and white) 10-30g, Rosa rugosa 3-10g, Chrysanthemum morifolium 3-10g, Rehmannia glutinosa (processed) 6-15g, Lonicera japonica 5-10g, Morus alba leaf 5-10g, Artemisia capillaris 5-10g, Gentiana scabra 5-10g, Poria cocos 5-10g, Astragalus membranaceus 5-20g, Curcuma longa 4-12g, Angelica sinensis 5-15g, Atractylodes macrocephala 5-12g, Polygonatum sibiricum. 10-18, Isatis root 7-15, hawthorn 15-30, Schisandra chinensis 4-12, rosin 1-5, frankincense 2-10, deer antler glue 3-15, Eucommia ulmoides 10-20, ephedra 1-8, aconite 1-8, licorice 2-30, yam 8-50, gentiana macrophylla 5-10, artemisia capillaris 9-15, sow thistle 5-30, bletilla striata 5-10, myrrh 3-9, carrot 10-25, eleutherococcus senticosus 6-12, drynaria fortunei 6-15;
[0019] Traditional Chinese medicine treatment for liver disease must be based on the patient's constitution, symptoms, tongue and pulse diagnosis and treatment.
[0020] 1. Honeysuckle: This herb has the effect of clearing heat and detoxifying, and can help treat symptoms of liver diseases such as hepatitis and jaundice.
[0021] 2. Mulberry leaves: Mulberry leaves are an herb that can help lower liver enzyme levels and may play a role in the treatment of cirrhosis.
[0022] 3. Artemisia capillaris: This is a traditional Chinese medicine that can clear heat and detoxify, and can also treat symptoms of liver diseases such as hepatitis and jaundice.
[0023] 4. Gentian: This herb can increase bile secretion, aid digestion and excretion, and also improve liver function.
[0024] 5. Poria: Poria is an herb that can help the liver detoxify and is often used to treat liver diseases such as cirrhosis.
[0025] 6. Astragalus: This herb can regulate the immune system and improve liver function.
[0026] Furthermore, the weight ratio of the raw materials also includes Bupleurum chinense 10-20g, Citrus reticulata peel 10-15g, Aucklandia lappa 4-15g, Cyperus rotundus 6-15g, Citrus medica 9-15g, Paeonia lactiflora 9-15g, Salvia miltiorrhiza 10-15g, Typha orientalis pollen 4-10g, Prunus persica kernel 10-20g, Carthamus tinctorius 2-10g, and Trionyx sinensis shell 12-25g; used to treat liver qi stagnation and qi and blood stasis.
[0027] Furthermore, the weight ratio of the raw materials may also include 6-15g of wolfberry, 8-15g of privet fruit, 10-15g of eclipta prostrata, 10-25g of mulberry, 5-15g of dodder seed, 5-15g of ophiopogon japonicus, and 12-20g of rehmannia root; used to treat liver and kidney yin deficiency.
[0028] Furthermore, the weight ratio of the raw materials may include 9-18 parts Epimedium, 4-10 parts Curculigo orchioides, 3-10 parts Psoralea corylifolia, and 8-15 parts Myristica fragrans; used to treat spleen and kidney yang deficiency.
[0029] Those skilled in the art can decoct the Chinese medicinal materials in this case. The specific decoction method is a well-known technique in the field. The following mainly introduces the working principle and process.
[0030] Example: Codonopsis pilosula, Paeonia lactiflora, Rosa rugosa, Chrysanthemum morifolium, Rehmannia glutinosa, Lonicera japonica, Mulberry leaf, Artemisia capillaris, Gentiana scabra, Poria cocos, Astragalus membranaceus, Curcuma longa, Angelica sinensis, Atractylodes macrocephala, Polygonatum sibiricum, Isatis indigotica, Crataegus pinnatifida, Schisandra chinensis, Rosin, Frankincense, Deer antler glue, Eucommia ulmoides, Ephedra sinica, Aconitum carmichaelii, Glycyrrhiza uralensis, Dioscorea opposita, Gentiana macrophylla, Artemisia capillaris, Sophora flavescens, Bletilla striata, Myrrh, Carrot, Acanthopanax senticosus, and Drynaria fortunei are used as adjunctive therapies for cirrhosis and liver cancer. Adding Bupleurum chinense, Citrus reticulata peel, Aucklandia lappa, Cyperus rotundus, Citrus medica, Paeonia lactiflora, Salvia miltiorrhiza, Typha orientalis, Prunus persica, Carthamus tinctorius, and Trionyx sinensis can treat symptoms of liver qi stagnation and blood stasis. Adding Lycium barbarum, Ligustrum lucidum, Eclipta prostrata, Mulberry, Cuscuta chinensis, Ophiopogon japonicus, and Rehmannia glutinosa can treat liver and kidney yin deficiency. Adding Epimedium brevicornu, Curculigo orchioides, Psoralea corylifolia, and Myristica fragrans can treat symptoms of spleen and kidney yang deficiency. Treatment for patients can be strengthened by addressing their specific symptoms.
[0031] It should be noted that, in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, the phrase "comprising an element defined as..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.
[0032] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A drug for treating cirrhosis and liver cancer, characterized in that, The ingredients are proportioned as follows by weight: Codonopsis pilosula 15-30g, Paeonia lactiflora (red and white) 10-30g, Rosa rugosa 3-10g, Chrysanthemum 3-10g, Rehmannia glutinosa (processed) 6-15g, Lonicera japonica 5-10g, Morus alba leaf 5-10g, Artemisia capillaris 5-10g, Gentiana scabra 5-10g, Poria cocos 5-10g, Astragalus membranaceus 5-20g, Curcuma longa 4-12g, Angelica sinensis 5-15g, Atractylodes macrocephala 5-12g, Polygonatum sibiricum 10-18g, Isatis indigotica root 7-1g.
5. Hawthorn 15-30g, Schisandra chinensis 4-12g, Rosin 1-5g, Frankincense 2-10g, Deer antler glue 3-15g, Eucommia ulmoides 10-20g, Ephedra 1-8g, Aconitum carmichaelii 1-8g, Licorice 2-30g, Dioscorea opposita 8-50g, Gentiana macrophylla 5-10g, Artemisia capillaris 9-15g, Sow thistle 5-30g, Bletilla striata 5-10g, Myrrh 3-9g, Carrot 10-25g, Acanthopanax senticosus 6-12g, Drynaria fortunei 6-15g.
2. The drug for treating cirrhosis and liver cancer according to claim 1, characterized in that, The weight ratio of the raw materials also includes Bupleurum chinense 10-20g, Citrus reticulata peel 10-15g, Aucklandia lappa 4-15g, Cyperus rotundus 6-15g, Citrus medica 9-15g, Paeonia lactiflora 9-15g, Salvia miltiorrhiza 10-15g, Typha orientalis pollen 4-10g, Prunus persica kernel 10-20g, Carthamus tinctorius 2-10g, and Trionyx sinensis shell 12-25g.
3. The drug for treating cirrhosis and liver cancer according to claim 1, characterized in that, The weight ratio of the raw materials may also include 6-15g of wolfberry, 8-15g of privet fruit, 10-15g of eclipta prostrata, 10-25g of mulberry, 5-15g of dodder seed, 5-15g of ophiopogon japonicus, and 12-20g of rehmannia root.
4. The drug for treating cirrhosis and liver cancer according to claim 1, characterized in that, The weight ratio of the raw materials may include 9-18 parts Epimedium, 4-10 parts Curculigo orchioides, 3-10 parts Psoralea corylifolia, and 8-15 parts Myristica fragrans.