Vibration mixing device for immunodetection

By using the coupling and decoupling design of the inner tapered tube and the conduit, combined with the linkage control of the telescopic component, the independent control of the vibration mixed state of a single test tube is realized. This solves the safety risks and operational inconvenience of picking up and placing test tubes in the existing technology, and improves the automation and efficiency of the testing process.

CN121927490APending Publication Date: 2026-04-28THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV
Filing Date
2026-03-23
Publication Date
2026-04-28

AI Technical Summary

Technical Problem

Existing vibratory mixers make it difficult to conveniently and safely remove individual test tubes without affecting the mixing effect of other test tubes during operation, posing safety risks and operational inconvenience.

Method used

A vibration mixing device for immunoassay was designed. By coupling the inner conical tube with the inner conical tube and decoupling the outer conical tube with the outer conical tube, the vibration mixing state of a single test tube can be independently controlled. The telescopic component drives the linkage component to work, so that the inner conical tube is separated from the inner conical tube, cutting off the transmission of vibration force, and moving the test tube to the outside for compression and fixation.

Benefits of technology

It achieves independent control of the vibration mixing state of a single test tube, solves the safety risks and operational inconvenience of manual handling of test tubes, improves the automation level of the testing process and overall work efficiency, and has a compact structure and controllable cost.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a vibration mixing device for immunodetection, and belongs to the technical field of immunodetection. Comprising a vibration mixing instrument main body, a control panel and an oscillation shaft are arranged on the vibration mixing instrument main body, a plurality of mounting grooves are uniformly distributed in the circumference of the outer surface of the oscillation shaft, mounting cylinders are arranged in the mounting grooves, the mounting cylinders are fixedly connected in the mounting grooves, and extrusion springs are arranged at the upper parts of the mounting cylinders. The upper end of the extrusion spring is fixed to the upper end of the mounting cylinder, the lower end of the extrusion spring is provided with an extrusion sliding block, the extrusion sliding block is slidably connected into the mounting cylinder, the upper surface of the extrusion sliding block is fixed to the extrusion spring, and a sliding column is arranged in the position, below the extrusion sliding block, of the mounting cylinder; a plurality of connecting columns which are evenly distributed in the circumferential direction are arranged between the sliding column and the extrusion sliding block. The technical scheme is used for solving the problem that when an existing vibration mixer works, a medical worker is difficult to conveniently take out one test tube under the condition that the mixing effect of other test tubes is not influenced.
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Description

Technical Field

[0001] This invention belongs to the field of immunoassay technology, and specifically relates to a vibration mixing device for immunoassay. Background Technology

[0002] In laboratory operations such as immunoassay and biochemical analysis, using vibration (or oscillation) to achieve rapid and thorough mixing of liquids and reagents in test tubes is a fundamental and crucial step.

[0003] Currently, most vibration mixers used in laboratories (such as vortex mixers) employ a holistic drive mode, where all test tubes placed on the platform begin vibrating simultaneously and continuously until a pre-set, unified timeout. This "batch processing" mode reveals significant limitations in actual workflows: when multiple test tubes require different mixing times due to variations in experimental steps, or need to be removed at different times for the next reaction, operators cannot safely and conveniently remove a single, already mixed test tube while the equipment is running continuously. Forcibly removing or placing the tube during vibration not only poses biosafety risks such as tube slippage and sample spillage but also interferes with the stable operation of the equipment and the mixing effect with other test tubes. Summary of the Invention

[0004] In view of this, the purpose of the present invention is to provide a vibratory mixing device for immunoassay, which solves the problem that when existing vibratory mixers are in operation, medical staff have difficulty in conveniently and safely removing one of the test tubes without affecting the mixing effect of the other test tubes.

[0005] To achieve the above objectives, the present invention provides the following technical solution: This invention discloses a vibration mixing device for immunoassay, comprising a vibration mixer body, a control panel and an oscillation shaft on the vibration mixer body, a plurality of mounting grooves evenly distributed around the outer surface of the oscillation shaft, and a mounting cylinder provided in each mounting groove, the mounting cylinder being fixedly connected to the mounting groove, a compression spring being provided at the upper part of the mounting cylinder, the upper end of the compression spring being fixed to the upper end of the mounting cylinder, a compression slider being provided at the lower end of the compression spring, the compression slider being slidably connected to the mounting cylinder, the upper surface of the compression slider being fixed to the upper part of the compression spring, and a sliding column being provided in the mounting cylinder below the compression slider. A plurality of circumferentially distributed connecting columns are provided between the sliding column and the extrusion slider. The two ends of the connecting columns are respectively fixed to the extrusion slider and the sliding column. A fixed cylinder is provided on the vibrating mixer body outside the mounting cylinder. One end of the fixed cylinder is fixed to the vibrating mixer body. A support spring is provided at the lower part of the fixed cylinder. The lower end of the support spring is fixed to the lower end of the mounting cylinder. A support slider is provided at the upper end of the support spring. The lower surface of the support slider is fixed to the upper end of the support spring. A telescopic component is provided at the upper end of the fixed cylinder. The telescopic component acts on the support slider to change the position of the support slider inside the fixed cylinder. A test tube is provided between the mounting tube and the fixing tube. An inner tapered tube and an outer tapered tube are symmetrically arranged on the test tube. An inner conduit and an outer conduit are respectively provided on the outer surfaces of the mounting tube and the fixing tube. The inner and outer conduits communicate with the interiors of the mounting tube and the fixing tube, respectively. The large-diameter ends of the inner and outer tapered tubes are fixed to the test tube. The small-diameter ends of the inner and outer conduits are located inside the inner and outer conduits, respectively. An inner traction rope and an outer traction rope are respectively provided on the small-diameter ends of the inner and outer tapered tubes. One end of the inner and outer traction ropes is connected to the small-diameter ends of the inner and outer tapered tubes, respectively, and the other end is connected to the sliding column and the supporting slider, respectively.

[0006] Furthermore, the telescopic assembly includes a connecting slider inside an mounting cylinder disposed above the supporting slider. A plurality of connecting rods are circumferentially arranged between the connecting slider and the supporting slider. The two ends of the connecting rods are respectively fixed to the upper surface of the supporting slider and the lower surface of the connecting slider. A smooth rod is provided on the upper surface of the connecting slider. The lower end of the smooth rod is connected to the upper surface of the connecting slider. The upper end of the smooth rod extends through the upper end of the fixing cylinder. A locking internal thread is provided in the middle of the upper end face of the fixing cylinder. A locking external thread matching the locking internal thread is provided on the upper outer surface of the smooth rod.

[0007] Furthermore, the test tube tube contains a first flexible clamp and a second flexible clamp, and a clamping space for accommodating the sampling test tube is provided between the first flexible clamp and the second flexible clamp.

[0008] Furthermore, the first flexible clamp is fixed to the inner wall of the test tube, and the outer wall of the second flexible clamp is provided with a push plate. The push plate is fixed to the second flexible clamp. A sliding shaft is provided in the middle of the push plate. One end of the sliding shaft is fixed to the push plate, and the other end of the sliding shaft extends out of the test tube. An inner baffle is provided on the other end of the sliding shaft. A clamping spring is sleeved on the sliding shaft. A fixing tube is provided on the outer side of the sliding shaft. The two ends of the clamping spring are respectively fixed to the inner baffle and the fixing tube.

[0009] Furthermore, the outer wall of the fixed cylinder outside the test tube is symmetrically provided with outer baffles. The middle part of the outer baffle is fixed to the fixed cylinder. The two ends of the outer baffle are symmetrically provided with push rods. One end of the push rod is fixed to the outer baffle, and the other end of the push rod is set towards the two ends of the inner baffle.

[0010] Furthermore, the vibrating mixer body below the test tube is provided with several vertical springs. One end of the vertical spring is fixed to the vibrating mixer body, and the other end of the vertical spring is provided with a contact plate. The contact plate is fixed to the vertical spring and is in contact with the lower end of the test tube. Side baffles are provided on both sides of the contact plate and are fixed to the two side surfaces of the contact plate. The test tube is located between the two side baffles.

[0011] Furthermore, an inner retaining ring and an outer retaining ring are respectively provided between the inner conduit and the outer conduit, and the outer walls of the inner retaining ring and the outer retaining ring are respectively fixed to the inner walls of the inner conduit and the outer conduit.

[0012] The beneficial effects of this invention are as follows: This technical solution ingeniously achieves independent and rapid "on / off" control of the vibration mixing state of a single test tube. During the mixing stage, through the coupling effect of the inner conical tube and the inner conduit, and the decoupling effect of the outer conical tube and the outer conduit, the vibration of the oscillation shaft is reliably transmitted to the test tube without interfering with the operation of the oscillation shaft. When it is necessary to remove the sample test tube after mixing, the linkage component in the drive device is activated by triggering the telescopic component, which causes the coupling surface of the inner conical tube and the inner conduit to disengage. This cuts off the transmission of vibration force to the test tube without interrupting the operation of the overall equipment and the mixing process of other test tubes, and moves the test tube to the outer test tube for compression and fixation, thus stably placing the mixed sample test tube.

[0013] This not only solves the safety risks and operational inconvenience of manually handling test tubes in a vibrating environment, but also allows for independent and precise control of the mixing time of different test tubes, thereby achieving truly asynchronous, continuous, and assembly-line operations, greatly improving the automation level and overall work efficiency of the testing process. At the same time, the entire control process relies on pure mechanical structure linkage, which is fast-responding, highly reliable, and does not require an independent vibration motor for each workstation, resulting in a compact structure and controllable cost.

[0014] Other advantages, objectives, and features of the invention will be set forth in the following description and will be apparent to those skilled in the art in some respects, or may be learned by practice of the invention. The objectives and other advantages of the invention can be realized and obtained through the following description. Attached Figure Description

[0015] To make the objectives, technical solutions, and beneficial effects of this invention clearer, the following figures are provided for illustration: Figure 1 This is a three-dimensional schematic diagram of the vibration mixing device for immunoassay of the present invention; Figure 2 This is a three-dimensional schematic diagram of the main body of the vibration mixer in the vibration mixing device for immunoassay of the present invention; Figure 3 This is a three-dimensional schematic diagram of the components arranged on the oscillation shaft in the vibratory mixing device for immunoassay of the present invention; Figure 4 This is a schematic cross-sectional view of the vibration mixing device for immunoassay of the present invention, in which relevant components are arranged on the oscillation shaft; Figure 5 This is a three-dimensional schematic diagram of the internal components arranged on the oscillation shaft of the vibratory mixing device for immunoassay of the present invention.

[0016] The following labels are shown in the attached diagram: 1. Vibrating mixer body; 2. Control panel; 3. Vibrating shaft; 4. Mounting slot; 5. Mounting cylinder; 6. Inner guide tube; 7. Sliding column; 8. Connecting column; 9. Extrusion slider; 10. Extrusion spring; 11. Test tube cylinder; 12. Inner conical tube; 13. Inner traction rope; 14. Fixing cylinder; 15. Support spring; 16. Support slider; 17. Connecting rod; 18. Connecting slider; 19. Smooth rod; 20. Outer cone 21. Outer traction rope; 22. Fixing tube; 23. Push plate; 24. Sliding shaft; 25. Clamping spring; 26. Inner baffle; 27. Outer baffle; 28. Top rod; 29. ​​Second flexible clamping block; 30. First flexible clamping block; 31. Lateral baffle; 32. Vertical spring; 33. Contact plate; 34. Sampling tube; 35. Outer conduit; 36. External thread; 37. Inner retaining ring; 38. Outer retaining ring. Detailed Implementation

[0017] like Figures 1-5 As shown, the present invention discloses a vibration mixing device for immunoassay, comprising a vibration mixer body 1, a control panel 2 and an oscillation shaft 3 on the vibration mixer body 1, a plurality of mounting grooves 4 evenly distributed around the outer surface of the oscillation shaft 3, and mounting cylinders 5 fixedly connected to the mounting grooves 4. A compression spring 10 is provided at the upper part of the mounting cylinder 5, the upper end of the compression spring 10 is fixed to the upper end of the mounting cylinder 5, and a compression slider 9 is provided at the lower end of the compression spring 10. The compression slider 9 is slidably connected to the mounting cylinder 5, and the upper surface of the compression slider 9 is fixed to the compression spring 10. A sliding post 7 is provided in the mounting cylinder 5 below the compression slider 9, and a connection is provided between the sliding post 7 and the compression slider 9. A number of circumferentially distributed connecting columns 8 are provided. The two ends of the connecting columns 8 are fixed to the extrusion slider 9 and the sliding column 7, respectively. A fixed cylinder 14 is provided on the vibrating mixer body 1 outside the mounting cylinder 5. One end of the fixed cylinder 14 is fixed to the vibrating mixer body 1. A support spring 15 is provided at the lower part of the fixed cylinder 14. The lower end of the support spring 15 is fixed to the lower end of the mounting cylinder 5. A support slider 16 is provided at the upper end of the support spring 15. The support slider 16 is slidably connected to the inside of the fixed cylinder 14. The lower surface of the support slider 16 is fixed to the upper end of the support spring 15. A telescopic component is provided at the upper end of the fixed cylinder 14. The telescopic component acts on the support slider 16 to change the position of the support slider 16 inside the fixed cylinder 14. A test tube tube 11 is provided between the mounting tube 5 and the fixing tube 14. An inner tapered tube 12 and an outer tapered tube 20 are symmetrically arranged on the test tube tube 11. An inner conduit 6 and an outer conduit 35 are respectively provided on the outer surfaces of the mounting tube 5 and the fixing tube 14, communicating with the interiors of the mounting tube 5 and the fixing tube 14. The large-diameter ends of the inner tapered tube 12 and the outer tapered tube 20 are fixed to the test tube tube 11, while the small-diameter ends of the inner conduit 6 and the outer conduit 35 are located on the inner and outer conduits, respectively. Preferably, the large-diameter ends of the inner tapered tube 12 and the outer tapered tube 20 are matched with the inner diameters of the inner conduit 6 and the outer conduit 35, respectively. The small-diameter ends of the inner tapered tube 12 and the outer tapered tube 20 are respectively provided with an inner traction rope 13 and an outer traction rope 21. One end of the inner traction rope 13 and the outer traction rope 21 is connected to the small-diameter ends of the inner tapered tube 12 and the outer tapered tube 20, respectively, and the other end of the inner traction rope 13 and the outer traction rope 21 is connected to the sliding column 7 and the support slider 16, respectively.

[0018] The working principle of the above technical solution is as follows: During vibration mixing: Under the action of the compression spring 10, the compression slider 9 is pushed downwards, thereby pressing the sliding column 7 against the lower end of the mounting cylinder 5. That is, the sliding column 7 pulls down the inner traction rope 13, causing the inner traction rope 13 to move the inner tapered tube 12 into the inner conduit 6 until the outer surface of the test tube 11 abuts against the end of the inner conduit 6. At this point, under the traction force of the inner traction rope 13, the test tube 11 is firmly and fixedly connected to the inner conduit 6. Meanwhile, due to the inward movement of the test tube 11, the outer tapered tube 12 will be pulled... The tube 20 moves so that the small-diameter end of the outer tapered tube 20 is located at the end of the outer conduit 35 (not detached, but not in contact), that is, the outer tapered tube 20 is not in contact with the outer conduit 35 at this time; that is, under the action of the oscillating shaft 3, the fixed cylinder 14 and the test tube cylinder 11 on the fixed cylinder 14 will be driven to perform vibration mixing operation. Since the outer tapered tube 20 and the outer sleeve are not in contact with each other, and the outer traction rope 21 itself can deform, the vibration of the oscillating shaft 3 will not be transmitted to the mounting cylinder 5, that is, it will not interfere with the operation of the oscillating shaft 3. When the vibration mixing at a certain position is completed: At this time, it is only necessary to manually operate the telescopic component or control the telescopic component to work through the control program (such as controlling the telescopic rod and other components to work according to the duration). The telescopic component moves down to contact the support slider 16, pushing the support slider 16 to compress the support spring 15 and move downward. At this time, it will drive the end of the outer traction rope 21 to move down, which will drive the outer conical tube 20 to move outward. This will then apply a force to the test tube 11, the inner conical tube 12, the inner traction rope 13 and the sliding column 7, causing the sliding column 7 to move upward against the force of the compression spring 10. This will then cause the inner conical tube 12 to move outward, so that the small diameter end of the inner conical tube 12 moves to the end of the inner conduit 6. At this time, the inner conical tube 12 and the inner conduit 6 are no longer in contact. At this time, the vibration of the oscillation shaft 3 cannot act on the test tube 11, thus ensuring that the vibration mixing time of the sampling test tube 34 in the test tube 11 at this point meets the preset requirements. Removal and insertion of sampling tube 34: Since the test tube 11 is no longer in contact with the oscillating shaft 3 at this time, medical staff can directly remove the sampling tube 34 from the test tube 11 and then insert the unmixed sampling tube 34. After insertion, it is only necessary to control the telescopic component to reset, which will lose the force on the supporting slider 16. At this time, under the action of the supporting spring 15, the outer traction rope 21 will relax. Under the reset action of the compression spring 10, it will drive the sliding column 7 to move down. Then, under the action of the inner traction rope 13, it will pull the test tube 11 and the inner conical tube 12 to move inward until they are pressed against and fixed on the inner catheter 6. The mixing operation can then be carried out with the action of the oscillating shaft 3. It is easy to understand that when the telescopic component is reset, it should be reset slowly so that the test tube 11 is subjected to the double traction action of the inner traction rope 13 and the outer traction rope 21, so that the test tube 11 is not easy to tilt or rotate.

[0019] It should be noted that the connecting rod 17 is designed to provide space for the movement of the inner traction rope 13, and to prevent the squeezing slider 9 or sliding column 7 from coming into contact with the inner traction rope 13, which would interfere with the movement of the squeezing slider 9 and sliding column 7 inside the mounting cylinder 5.

[0020] The technical effects achieved by the above technical solution are as follows: This technical solution ingeniously achieves independent and rapid "on / off" control of the vibration mixing state of a single test tube. During the mixing stage, through the coupling effect of the inner conical tube 12 and the inner conduit 6, and the decoupling effect of the outer conical tube 20 and the outer conduit 35, the vibration of the oscillation shaft 3 is reliably transmitted to the test tube cylinder 11 without interfering with the operation of the oscillation shaft 3. When it is necessary to remove the sample test tube 34 after mixing, the linkage component in the drive device is activated by triggering the telescopic component, so that the coupling surface of the inner conical tube 12 and the inner conduit 6 is disengaged. Thus, without interrupting the operation of the overall equipment and the mixing process of other test tubes, the transmission of vibration force to the test tube is cut off, and the test tube cylinder 11 is moved to the outer test tube for compression and fixation, so as to stably place the sample test tube 34 after mixing.

[0021] This not only completely solves the safety risks and operational inconvenience of manually handling test tubes in a vibrating environment, but also allows the mixing time of different test tubes to be controlled independently and precisely, thus realizing truly asynchronous, continuous, and assembly-line operations, greatly improving the automation level of the testing process and overall work efficiency. At the same time, the entire control process relies on pure mechanical structure linkage, which is fast-responding, highly reliable, and does not require an independent vibration motor for each workstation, resulting in a compact structure and controllable cost.

[0022] In one feasible embodiment, the telescopic assembly includes a mounting cylinder 5 disposed above the support slider 16, within which a connecting slider 18 is provided. A plurality of connecting rods 17 are circumferentially disposed between the connecting slider 18 and the support slider 16. The two ends of the connecting rods 17 are respectively fixed to the upper surface of the support slider 16 and the lower surface of the connecting slider 18. A smooth rod 19 is provided on the upper surface of the connecting slider 18. The lower end of the smooth rod 19 is connected to the upper surface of the connecting slider 18. The upper end of the smooth rod 19 extends through the upper end of the fixing cylinder 14. A locking internal thread is provided in the middle of the upper end face of the fixing cylinder 14. A locking external thread 36 matching the locking internal thread is provided on the upper outer surface of the smooth rod 19.

[0023] By pressing down on the optical rod 19, it moves downwards and acts on the support slider 16, which in turn moves the support slider 16 downwards. When the support slider 16 moves to the designated position, the locking external thread 36 on the optical rod 19 and the locking internal thread at the end of the fixing cylinder 14 can achieve a threaded connection, thereby fixing the position of the optical rod 19. It is easy to understand that the optical rod 19 can be fixed to the support slider 16 by bearings, which can achieve a stable connection while allowing relative rotation for threaded connection. Of course, it is also easy to understand that the telescopic component can also achieve timed control through components such as telescopic rods and time delay relays, which will not be elaborated on here.

[0024] In one feasible embodiment, the test tube tube 11 has a first flexible clamping block 30 and a second flexible clamping block 29 inside, and a clamping space for accommodating the sampling test tube 34 is provided between the first flexible clamping block 30 and the second flexible clamping block 29. The first flexible clamping block 30 and the second flexible clamping block 29 can be made of foam board or foamed plastic board, that is, they have a certain deformation capacity, which can achieve clamping without causing compression damage to the sampling test tube 34.

[0025] In one feasible embodiment, a first flexible clamping block 30 is fixed to the inner wall of the test tube 11, a push plate 23 is provided on the outer wall of a second flexible clamping block 29, the push plate 23 is fixed to the second flexible clamping block 29, a sliding shaft 24 is provided in the middle of the push plate 23, one end of the sliding shaft 24 is fixed to the push plate 23, the other end of the sliding shaft 24 extends out of the test tube 11, and an inner baffle 26 is provided on the other end of the sliding shaft 24. A clamping spring 25 is sleeved on the sliding shaft 24, and a fixing tube 22 is sleeved on the outer side of the sliding shaft 24. One end of the fixing tube 22 is fixed to the test tube 11, and both ends of the clamping spring 25 are fixed to the inner baffle 26 and the fixing tube 22 respectively, and the clamping spring 25 is located inside the fixing tube 22.

[0026] When the sampling tube 34 is inserted, it will squeeze the first flexible clamp and the second flexible clamp (both of which are funnel-shaped at the top to facilitate the insertion of the sampling tube 34), thereby pushing the push plate 23 and the sliding shaft 24 to move outward of the test tube cylinder 11, which in turn causes the clamping spring 25 to deform, and the force of the clamping spring 25 to act on the sampling tube 34, ensuring stable clamping of different types of test tubes (the sampling tube 34 itself can withstand a certain pressure, and will not be squeezed and damaged due to the large deformation of the clamping spring 25 caused by its large diameter).

[0027] In one feasible embodiment, an outer baffle 27 is symmetrically provided on the outer wall of a fixed cylinder 14 located outside the test tube 11. The middle part of the outer baffle 27 is fixed to the fixed cylinder 14. A push rod 28 is symmetrically provided on both ends of the outer baffle 27. One end of the push rod 28 is fixed to the outer baffle 27, and the other end of the push rod 28 is set towards the two ends of the inner baffle 26.

[0028] Through a clever linkage structure, when the telescopic component moves the test tube 11 outward (towards the fixed tube 14), the top rod 28 on the fixed tube 14 will press the inner baffle 26, thereby driving the sliding shaft 24 to move outward of the test tube 11 (the lower end can be closed), thereby reducing the force of the clamping spring 25 on the sampling test tube 34, so that the sampling test tube 34 loses the clamping torque, which makes it convenient for medical staff to directly remove the sampling test tube 34.

[0029] In one feasible embodiment, a plurality of vertical springs 32 are provided on the vibrating mixer body 1 below the test tube 11. One end of the vertical spring 32 is fixed to the vibrating mixer body 1, and a contact plate 33 is provided on the other end of the vertical spring 32. The contact plate 33 is fixed to the vertical spring 32 and is in contact with the lower end of the test tube 11. Lateral baffles 31 are provided on both sides of the contact plate 33 and are fixed on both sides of the contact plate 33.

[0030] When the telescopic assembly operates, causing the test tube 11 to move towards the fixed tube 14, the contact plate 33 is in a horizontal state under the action of the vertical spring 32. This means that the lower end of the test tube 11 contacts the contact plate 33, and the outer wall of the test tube 11 is held in place by the side baffles 31 on both sides. This prevents the test tube 11 from falling or deflecting, ensuring that the test tube 11 remains vertical during translation. It is easy to understand that both the contact plate 33 and the side baffles 31 are connected to the vertical spring. When the test tube 11 on the spring 32 deflects with the vibration of the oscillating shaft 3, its contact with the contact plate 33 and the side baffle 31 will cause the vertical synchronous spring to deflect and deform, thus not affecting the vibration effect of the test tube 11. Furthermore, if the test tube 11 deflects under the vibration, the vertical spring 32 will also drive the test tube 11 back to the vertical state due to its own reset action, thereby ensuring that the sampling test tube 34 inside the test tube 11 is always in a vertical state and will not cause the internal liquid to splash out due to tilting.

[0031] In one feasible embodiment, an inner retaining ring 37 and an outer retaining ring 38 are respectively provided between the inner conduit 6 and the outer conduit 35. The outer walls of the inner retaining ring 37 and the outer retaining ring 38 are respectively fixed to the inner walls of the inner conduit 6 and the outer conduit 35. Both the inner retaining ring 37 and the outer retaining ring 38 can be rubber rings, which improves the limiting effect on the inner tapered tube 12 and the outer tapered tube 20. Under the extrusion force, the rotational friction force and the stable contact effect can be increased, avoiding the problem of relative rotation between the test tube tube 11 and the fixed tube 14 during vibration mixing.

[0032] Finally, it should be noted that the above preferred embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit it. Although the present invention has been described in detail through the above preferred embodiments, those skilled in the art should understand that various changes can be made to it in form and detail without departing from the scope defined by the claims of the present invention.

Claims

1. A vibration mixing device for immunoassay, comprising a vibration mixer body, wherein the vibration mixer body is provided with a control panel and an oscillation shaft, characterized in that: The outer surface of the oscillating shaft is provided with several mounting grooves evenly distributed around its circumference. Each mounting groove contains a mounting cylinder, which is fixedly connected to the mounting groove. A compression spring is provided at the upper part of the mounting cylinder, and the upper end of the compression spring is fixed to the upper end of the mounting cylinder. A compression slider is provided at the lower end of the compression spring, and the compression slider is slidably connected to the mounting cylinder. The upper surface of the compression slider is fixed to the compression spring. A sliding column is provided in the mounting cylinder below the compression slider. Several circumferentially distributed connecting columns are provided between the sliding column and the compression slider. The two ends of the connecting columns are fixed to the compression slider and the sliding column, respectively. A fixed cylinder is provided on the vibrating mixer body outside the mounting cylinder. One end of the fixed cylinder is fixed to the vibrating mixer body. A support spring is provided at the lower part of the fixed cylinder, and the lower end of the support spring is fixed to the lower end of the mounting cylinder. A support slider is provided at the upper end of the support spring, and the lower surface of the support slider is fixed to the upper end of the support spring. A telescopic component is provided at the upper end of the fixed cylinder. The telescopic component acts on the support slider to change the position of the support slider inside the fixed cylinder. A test tube is provided between the mounting tube and the fixing tube. An inner tapered tube and an outer tapered tube are symmetrically arranged on the test tube. An inner conduit and an outer conduit are respectively provided on the outer surfaces of the mounting tube and the fixing tube. The inner and outer conduits communicate with the interiors of the mounting tube and the fixing tube, respectively. The large-diameter ends of the inner and outer tapered tubes are fixed to the test tube. The small-diameter ends of the inner and outer conduits are located inside the inner and outer conduits, respectively. An inner traction rope and an outer traction rope are respectively provided on the small-diameter ends of the inner and outer tapered tubes. One end of the inner and outer traction ropes is connected to the small-diameter ends of the inner and outer tapered tubes, respectively, and the other end is connected to the sliding column and the supporting slider, respectively.

2. The vibratory mixing device for immunoassay according to claim 1, characterized in that: The telescopic assembly includes a connecting slider inside an mounting cylinder positioned above the supporting slider. Several connecting rods are circumferentially arranged between the connecting slider and the supporting slider. The two ends of the connecting rods are respectively fixed to the upper surface of the supporting slider and the lower surface of the connecting slider. A smooth rod is provided on the upper surface of the connecting slider. The lower end of the smooth rod is connected to the upper surface of the connecting slider. The upper end of the smooth rod extends through the upper end of the fixing cylinder. A locking internal thread is provided in the middle of the upper end face of the fixing cylinder. A locking external thread matching the locking internal thread is provided on the upper outer surface of the smooth rod.

3. The vibratory mixing device for immunoassay according to claim 1, characterized in that: The test tube contains a first flexible clamp and a second flexible clamp, with a clamping space between the first flexible clamp and the second flexible clamp for accommodating the sample test tube.

4. The vibratory mixing device for immunoassay according to claim 3, characterized in that: The first flexible clamp is fixed to the inner wall of the test tube. The outer wall of the second flexible clamp is provided with a push plate, which is fixed to the second flexible clamp. A sliding shaft is provided in the middle of the push plate. One end of the sliding shaft is fixed to the push plate, and the other end of the sliding shaft extends out of the test tube. An inner baffle is provided on the other end of the sliding shaft. A clamping spring is sleeved on the sliding shaft. A fixing tube is provided on the outer side of the sliding shaft. The two ends of the clamping spring are respectively fixed to the inner baffle and the fixing tube.

5. The vibratory mixing device for immunoassay according to claim 4, characterized in that: The outer wall of the fixed cylinder outside the test tube is symmetrically provided with outer baffles. The middle part of the outer baffle is fixed to the fixed cylinder. The two ends of the outer baffle are symmetrically provided with push rods. One end of the push rod is fixed to the outer baffle, and the other end of the push rod is set towards the two ends of the inner baffle.

6. The vibratory mixing device for immunoassay according to claim 1, characterized in that: The vibrating mixer body below the test tube is equipped with several vertical springs. One end of each vertical spring is fixed to the vibrating mixer body, and the other end of each vertical spring is equipped with a contact plate. The contact plate is fixed to the vertical spring and is in contact with the lower end of the test tube. Side baffles are provided on both sides of the contact plate and are fixed to the two side surfaces of the contact plate. The test tube is located between two of the side baffles.

7. The vibratory mixing device for immunoassay according to claim 1, characterized in that: An inner retaining ring and an outer retaining ring are respectively provided between the inner conduit and the outer conduit, and the outer walls of the inner retaining ring and the outer retaining ring are respectively fixed to the inner walls of the inner conduit and the outer conduit.