Paraffin embedding device for pathological section and control method thereof
By designing a phased embedding and freezing process and recycling energy, the problems of insufficient transfer and cooling in automated paraffin embedding equipment were solved, achieving an efficient and standardized paraffin embedding process and improving section quality and work efficiency.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SHENZHEN SECOND PEOPLES HOSPITAL (SHENZHEN INST OF TRANSLATIONAL MEDICINE)
- Filing Date
- 2025-12-18
- Publication Date
- 2026-05-08
AI Technical Summary
Existing automated paraffin embedding equipment lacks orderly transfer and uniform cooling functions, making it difficult to control the amount of paraffin used, which can easily lead to overflow, poor wax block formation, and affect the quality of sections and diagnostic accuracy.
The design employs a staged embedding and freezing process, utilizing a first and second wax dripping machine in conjunction with first and second freezing plates, along with roller transport components and roadblock assemblies, to achieve automated positioning and uniform cooling of tissue blocks. Energy is recycled through the cooling and heating sections of the temperature control equipment.
It improves the internal quality and structural integrity of paraffin-embedded blocks, reduces human error, increases work efficiency, reduces energy consumption, and ensures slice quality and diagnostic accuracy.
Smart Images

Figure FT_1 
Figure FT_2 
Figure FT_3
Abstract
Description
Technical Field
[0001] This invention relates to the field of paraffin embedding, and more specifically, to a paraffin embedding device for pathological sections and a control method thereof. Background Technology
[0002] In pathological diagnosis and research, paraffin sectioning is the core and foundation of histological specimen preparation. This technique involves a series of rigorous steps, including specimen collection, fixation, dehydration, clearing, paraffin infiltration, embedding, sectioning, spreading, and staining, to prepare biological tissue into thin sections suitable for microscopic observation. The paraffin embedding step is particularly crucial, aiming to completely immerse and seal the pre-treated tissue block in paraffin, forming a wax block with a certain degree of hardness and toughness, thus providing the necessary structural support for subsequent high-quality ultrathin sections.
[0003] Traditional paraffin embedding is highly manual. The basic process is as follows: the operator places the paraffin-impregnated tissue block at the bottom of a specific metal mold, then manually injects molten paraffin into the mold, and finally covers the mold and transfers it to a freezing table for rapid cooling and solidification.
[0004] However, the amount of paraffin used is difficult to control precisely. The amount of wax injected depends entirely on the operator's personal experience. It is very easy to inject too much paraffin, resulting in overflow, waste of paraffin, and contamination of the work surface and environment; or inject too little, resulting in poor wax block formation and insufficient tissue support, which can cause cracks, wrinkles and other problems when sectioning, seriously affecting the quality of the final section and the accuracy of diagnosis.
[0005] To address the aforementioned issues, some automated or semi-automated paraffin embedding devices have emerged on the market. However, existing automated devices still have significant shortcomings in key functionalities. They generally lack modules capable of achieving orderly, targeted transfer and uniform cooling, resulting in limited effectiveness in improving standardization and batch processing efficiency. Therefore, developing a paraffin embedding device capable of achieving orderly transfer and uniform cooling to meet the growing demands of pathology laboratories for high throughput, standardization, and high quality has become an urgent technical problem to be solved in this field. Summary of the Invention
[0006] The purpose of this invention is to solve the problems of the prior art mentioned above and to provide a paraffin embedding device for pathological sections; Another object of the present invention is to provide a control method for a paraffin embedding device.
[0007] This invention is achieved using the following technical solution: A paraffin embedding device for pathological sections includes: a worktable, a wax filling device, a transport section, a freezing stage, a temperature control device, and an embedding mold; The workbench is provided with a wax cavity, the freezing stage and the transport component are arranged on the workbench, and the wax cavity is connected to the wax filling device; The wax-filling device includes a first wax-drip machine and a second wax-drip machine, and the freezing stage includes a first freezing plate and a second freezing plate; The first freezing plate is positioned below the first wax dripping machine and is used to initially embed and freeze the tissue block of the embedding mold. The second wax dripping machine is positioned above the transport component and is used to completely embed the initially embedded tissue block; The transport component is provided with a second freezing plate at its end, which is used to transport the embedding mold of the completely embedded tissue block to the second freezing plate for final freezing treatment. The refrigeration section of the temperature control device is connected to the freezing stage, and its heating section is connected to the wax chamber.
[0008] Furthermore, the temperature control device includes a compressor, a condensing coil, a throttling mechanism, and an evaporating coil; the compressor outlet is connected to the condensing coil, and the condensing coil is connected to the evaporating coil through the throttling mechanism; a portion of the condensing coil is disposed within the wax cavity to provide heat to the wax cavity; the evaporating coil is disposed in conjunction with the freezing stage to cool the freezing stage, causing the wax within the embedding mold to solidify.
[0009] Furthermore, the workbench is also provided with a heat dissipation cavity, and some of the condensing coils are also disposed in the heat dissipation cavity. The heat dissipation cavity is provided with convection openings and heat exchange is carried out by a fan.
[0010] Furthermore, the workbench is also provided with a moving trough, and the transport component includes several rollers arranged in a row on the moving trough. The rollers are also connected to a motor to enable the embedding mold to be automatically transported along the row of rollers.
[0011] Furthermore, a wax receiving box can be detachably installed at the bottom of the moving trough. The wax receiving box is located below the roller and is used to collect wax droplets that fall during the embedding process.
[0012] Furthermore, the transport component also includes a roadblock assembly, which is disposed below the second wax dripping machine to block and position the embedding mold moving on the roller below the second wax dripping machine for wax collection.
[0013] Preferably, the roadblock assembly includes a drive motor, a rotating shaft, and a baffle. The drive motor is fixed above the worktable, and its output end is connected to the rotating shaft; The baffle is fixedly installed on the rotating shaft and can rotate vertically under the drive of the drive motor. It has a blocking station that is raised to block the embedding mold and a passage station that is flat to allow the embedding mold to pass through.
[0014] Furthermore, the first freezing plate is also provided with a movable mounting platform for placing the embedding mold, the movable mounting platform including a receiving plate, a spring frame and a spring frame; The elastic frame is disposed at the bottom of the support plate and is used to provide a restoring force when the support plate moves downward; The receiving plate is positioned above the first freezing plate via the spring frame.
[0015] Furthermore, the embedding mold includes a metal base box for embedding pathological sections and a mesh cover; the mesh cover can be fitted over the metal base box.
[0016] A control method for the paraffin embedding apparatus, the control method for the paraffin embedding apparatus comprising the following: S1: Turn on the temperature control device. After reaching the appropriate temperature, place the embedding mold containing the tissue block on the first freezing plate. Start the first wax dripping machine to drip molten paraffin into the embedding mold for preliminary embedding. At the same time, the temperature control device cools the first freezing plate to solidify the paraffin that has been initially embedded. S2: Then, the embedding mold that has undergone preliminary embedding and freezing is transferred to the starting end of the transport component, and the embedding mold moves under the rotation of the rollers; S3: When the embedding mold moves to the bottom of the second wax dripping machine, it is blocked and positioned by the roadblock component. The second wax dripping machine drips molten paraffin into the embedding mold to complete the embedding. S4: When the molten paraffin dripped into the embedding mold is completely embedded, the obstruction of the roadblock component is removed. The fully embedded embedding mold continues to move along the transport component to its end and reaches the second freezing plate for final freezing treatment. After the paraffin is completely solidified, the embedded embedding mold is removed.
[0017] Furthermore, in step S2, the scattered wax droplets are caught by a wax collection box located below the roller.
[0018] Compared with the prior art, the beneficial effects of the technical solution of the present invention are:
[0019] 1. This invention, by setting up a first and a second paraffin dripping machine, along with first and second freezing plates, achieves a phased processing of tissue blocks from "preliminary embedding + preliminary freezing" to "complete embedding + final freezing." This process effectively avoids problems such as tissue block displacement, coarse paraffin crystals, and internal air bubbles caused by excessive paraffin filling or uneven cooling, thereby significantly improving the internal quality and structural integrity of the paraffin-embedded blocks and laying a solid foundation for the subsequent production of high-quality pathological sections.
[0020] 2. The roller transport component and the roadblock assembly of this invention work together to achieve automatic and continuous transfer of the embedding mold between the three stations of preliminary embedding, complete embedding, and final freezing. This greatly reduces the time spent on manual handling and positioning, avoids errors or contamination that may be introduced by human operation, and makes the entire embedding process efficient and standardized, significantly improving work efficiency.
[0021] 3. This invention innovatively uses the refrigeration part of the temperature control device for refrigeration of the freezing platform, while using its heating part (i.e., the heat emitted by the condenser coil) to heat the paraffin in the wax chamber. This design converts the condensation heat that is usually wasted in the refrigeration cycle into a useful heat source, realizing the internal circulation and efficient utilization of energy, significantly reducing the extra energy consumption of the device to maintain the molten state of the paraffin, and embodying the green and energy-saving design concept. Attached Figure Description
[0022] Figure 1 This is a schematic diagram of the paraffin embedding device of the present invention; Figure 2 This is a structural diagram of the internal temperature control device of the paraffin embedding apparatus of the present invention; Figure 3 This is a schematic diagram of the embedding mold of the present invention working on the worktable; Figure 4 This is an enlarged schematic diagram of invention B; Figure 5 This is a top view of the paraffin embedding apparatus of the present invention; Figure 6 This is a schematic diagram of the structure of the embedding mold and the movable mounting platform of the present invention. Figure 7 This is a schematic diagram of the structure of the workbench of the present invention; Figure 8 This is a schematic diagram of the structure of the roller of the present invention installed in the moving trough; Figure 9 This is a schematic diagram of the structure of the metal base box of the present invention; Figure 10 This is a schematic diagram of the structure of the mesh cover of the present invention; Figure 11 This is a structural schematic diagram of the support plate and elastic frame of this invention; in: 1. Worktable; 101. Wax chamber; 102. Heat dissipation chamber; 103. Moving slot; 104. Refrigeration chamber; 2. Wax-pouring device; 201. First wax-drip machine; 202. Second wax-drip machine; 3. Transport components; 301. Rollers; 302. Roadblock assembly; 4. Freezing platform; 401. First freezing plate; 402. Second freezing plate; 5. Temperature control equipment; 501. Compressor; 502. Condensing coil; 503. Throttling mechanism; 504. Evaporator coil; 6. Embedding mold; 601. Metal base box; 602. Mesh cover; 7. Fan; 8. Wax collection box; 9. Mobile mounting platform; 901. Support plate; 902. Elastic frame; 903. Spring frame. Detailed Implementation
[0023] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of this application will be clearly and completely described below with reference to the accompanying drawings of the embodiments of this application. Obviously, the described embodiments are only some, not all, of the embodiments of this application. All other embodiments obtained by those skilled in the art based on the described embodiments without creative effort are within the scope of protection of this application.
[0024] Unless otherwise defined, the technical or scientific terms used in this application shall have the ordinary meaning understood by one of ordinary skill in the art to which this application pertains. The terms "first," "second," and similar terms used in this application do not indicate any order, quantity, or importance, but are merely used to distinguish different components. Terms such as "comprising" or "including" mean that the element or object preceding the word encompasses the elements or objects listed following the word and their equivalents, without excluding other elements or objects. Terms such as "connected" or "linked" are not limited to physical or mechanical connections, but can include electrical connections, whether direct or indirect. Terms such as "upper," "lower," "left," and "right" are used only to indicate relative positional relationships; when the absolute position of the described object changes, the relative positional relationship may also change accordingly.
[0025] Example 1 like Figure 1-11 This embodiment discloses a paraffin embedding device for pathological sections.
[0026] A paraffin embedding device for pathological sections includes: a worktable 1, a wax filling device 2, a transport component 3, a freezing stage 4, a temperature control device 5, and an embedding mold 6; A wax chamber 101 is provided on the workbench 1, and a freezing stage 4 and a transport component 3 are set on the workbench 1. The wax chamber 101 is connected to the wax filling device 2. The wax-filling device 2 includes a first wax-drip machine 201 and a second wax-drip machine 202, and the freezing table 4 includes a first freezing plate 401 and a second freezing plate 402; The first freezing plate 401 is placed below the first wax dripping machine 201 and is used to initially embed and freeze the tissue block of the embedding mold 6; The second wax dripping machine 202 is positioned above the transport component 3 and is used to completely embed the initially embedded tissue block; The transport component 3 is provided with a second freezing plate 402 at its end, which is used to transport the embedding mold 6 that completely embeds the tissue block to the second freezing plate 402 for final freezing treatment. The refrigeration section of the temperature control device 5 is connected to the freezing stage 4, and its heating section is connected to the wax chamber 101.
[0027] The temperature control device 5 includes a compressor 501, a condenser coil 502, a throttling mechanism 503, and an evaporator coil 504; the outlet of the compressor 501 is connected to the condenser coil 502, and the condenser coil 502 is connected to the evaporator coil 504 through the throttling mechanism 503; part of the condenser coil 502 is disposed in the wax chamber 101 to provide heat to the wax chamber 101; the evaporator coil 504 is disposed in close contact with the freezing stage 4 to cool the freezing stage 4 so that the wax in the embedding mold 6 solidifies.
[0028] The workbench 1 is also equipped with a moving trough 103. The transport component 3 includes several rollers 301, which are arranged in a row on the moving trough 103 to enable the embedding mold 6 to be automatically transported along the row of rollers 301. The rollers 301 are also connected to a motor for transmission.
[0029] The workbench 1 is also provided with a heat dissipation cavity 102, and some of the condensing coils 502 are also provided in the heat dissipation cavity 102. The heat dissipation cavity 102 is provided with convection openings and heat exchange is carried out through the fan 7.
[0030] Specifically, as the core of temperature control in this device, a compression refrigeration cycle (including compressor 501, condenser coil 502, throttling mechanism 503 and evaporator coil 504) is adopted. Innovatively, the refrigeration part (evaporator coil 504) is used to refrigerate the freezing stage, while the heating part (part of condenser coil 502) is placed in the wax chamber 101 to provide the heat required for the melting of paraffin wax, thus realizing the efficient recycling of energy.
[0031] Specifically, the workbench 1 is provided with a refrigeration cavity 104, and the evaporator coil 504 is laid in the refrigeration cavity 104; the bottoms of the first freezing plate 401 and the second freezing plate 402 are embedded and fixed to the top of the refrigeration cavity 104, so that the cold energy generated by the evaporator coil 504 can be directly transferred to the freezing plate.
[0032] To further improve heat exchange efficiency and temperature uniformity, a circulating fan is also provided in the refrigeration cavity 104. The circulating fan causes the cold air in the refrigeration cavity 104 to flow, and quickly and evenly transfers the cold energy generated by the evaporator coil 504 to the entire bottom surface of the first freezing plate 401 and the second freezing plate 402, thereby causing the paraffin in the embedding mold 6 to solidify rapidly.
[0033] At the start of the operation, turn on the temperature control device 5, place the metal base box 601 containing the tissue block to be embedded on the movable mounting stage 9, and use tweezers to lay the surface of the tissue block to be embedded flat on the bottom of the metal base box 601. Then, start the first wax dripping machine 201 to inject an appropriate amount of molten paraffin into the metal base box 601 to initially embed the tissue block. At the same time, the temperature control device 5 works, and the evaporation coil 504 cools the first freezing plate 401. By manually pressing down the metal base box 601, the movable mounting stage 9 below is moved and pressed down, so that the metal base box 601 contacts the first freezing plate 401, ensuring that the initially embedded paraffin solidifies quickly, thereby fixing the position of the tissue block.
[0034] After the paraffin wax that has been initially embedded solidifies, the operator covers the metal base box 601 with a mesh cover 602, removes it from the mobile mounting platform 9, and places it at the starting end of the transport component 3 (i.e., the high end of the roller 301); the motor drives the roller 301 to rotate, and the metal base box 601 slides under the rotation of the roller 301. When the mold slides directly below the second wax dripping machine 202, it is precisely blocked and positioned by the roadblock component 302. Then, the second wax dripping machine 202 is activated to inject molten paraffin wax onto the mesh cover 602. The molten paraffin wax falls from the mesh into the metal base box 601 until it completely covers the tissue block, thus completing the complete embedding process. During this process, any scattered wax droplets will be collected by the wax receiving box 8 below.
[0035] Once the encapsulation is complete, the barrier assembly 302 is released, and the encapsulation mold 6 continues to move along the roller 301 to the end of the transport component and enters the second freezing plate 402 for final freezing treatment to ensure that the paraffin wax is completely solidified and formed. Finally, the operator removes the formed paraffin wax encapsulation block from the second freezing plate 402, and the entire encapsulation process is completed.
[0036] Specifically, the second freezing plate 402 is set up, and the embedding mold 6 enters from the end of the transport component and arrives at the second freezing plate 402, falling onto the second freezing plate 402; the operator only needs to arrange the embedding molds 6 on the second freezing plate 402 in an orderly manner and wait for cooling, and then collect the paraffin embedding block that has been completely solidified.
[0037] As one example, The bottom of the moving trough 103 can also be detachably equipped with a wax receiving box 8, which is located below the roller 301 and is used to receive the wax droplets that fall during the embedding process.
[0038] Specifically, the embedding mold 6 is transferred under the rotation of the roller 301; the uniform arrangement of the roller 301 ensures that the embedding mold 6 moves smoothly; when the embedding mold 6 moves to the bottom of the second wax dripping machine 202, it is precisely blocked by the roadblock component 302.
[0039] When the second wax dripping machine 202 performs the complete encapsulation operation, the wax droplets are easy to splash and scatter into the wax receiving box 8 in the moving groove 103. The wax receiving box 8 can receive the scattered wax droplets throughout the entire working cycle; the wax receiving box 8 can also be removed periodically for cleaning and maintenance.
[0040] The mobile trough solution of the present invention, through its ingenious structural design, realizes the automatic transportation of the embedding mold 6 and the effective collection of scattered wax droplets, greatly improving the automation level and work efficiency of paraffin embedding.
[0041] As one embodiment, the first freezing plate 401 is also provided with a movable mounting platform 9 for placing the embedding mold 6. The movable mounting platform 9 includes a receiving plate 901, a spring frame 902 and a spring frame 903. The elastic frame 902 is disposed at the bottom of the receiving plate 901 and is used to provide a restoring force when the receiving plate 901 moves downward; The receiving plate 901 is positioned above the first freezing plate 401 via the spring frame 903.
[0042] Specifically, the first freezing plate 401 is provided with a spring groove, and the spring bracket 903 is disposed in the spring groove.
[0043] Specifically, the elastic frame 902 consists of multiple supporting elastic rods, which are inclinedly positioned below the receiving plate 901 and in contact with the workbench 1; when the receiving plate 901 moves downward, the elastic rods bend outward and tilt to store elastic potential energy.
[0044] During the initial embedding stage, the first wax dripping machine 201 is started to inject an appropriate amount of molten paraffin into the metal base box 601; the operator applies appropriate pressure to press down the metal base box 601, which drives the receiving plate 901 to move downward, thereby compressing the elastic frame 902 downward and bending the elastic frame 902 outward, ensuring that the metal base box 601 is in close contact with the first freezing plate 401.
[0045] During the solidification stage, the downward pressure is maintained to ensure that the bottom of the metal base box 601 is in full contact with the first freezing plate 401 for heat conduction; the temperature control device 5 quickly conducts away the heat through the first freezing plate 401, causing the paraffin to solidify rapidly; during this process, the elastic frame 902 continuously provides stable support.
[0046] When the embedding mold 6 is removed from the movable mounting table 9 and placed on the transport component 3, the elastic potential energy stored in the elastic frame 902 and the spring frame 903 is released, pushing the receiving plate 901 to move upward and reset, thereby moving away from the first freezing plate 401, thus ensuring that the tissue block is completely immersed in the paraffin and solidifies during the next initial embedding.
[0047] As one embodiment, the embedding mold 6 includes a metal base box 601 for embedding pathological sections and a mesh cover 602; the mesh cover 602 can be fitted over the metal base box 601.
[0048] In the preparation stage, clean the metal base box 601 to ensure that there are no impurities on the surface; place the metal base box 601 to be inspected on the mobile mounting stage 9, use tweezers to lay the surface of the tissue block to be inspected flat on the bottom of the metal base box 601, and then start the wax injection device 2 to inject an appropriate amount of molten paraffin into the metal base box 601 to initially embed the tissue block. After the initial embedding is completed, a mesh cover 602 is placed on top of the metal base box 601 and transported to the bottom of the second wax dripping machine 202 via the transport component 3. Molten paraffin is then injected onto the mesh cover 602, falling from the mesh into the metal base box 601 until the tissue block is completely covered, thus completing the complete embedding process. It then proceeds to the second freezing plate 402 for final freezing treatment, ensuring that the paraffin wax completely solidifies and takes shape. At the start of the operation, turn on the temperature control device 5. After reaching the appropriate temperature, first place the metal base box 601 containing the tissue block to be inspected on the movable mounting stage 9. Use tweezers to lay the surface of the tissue block to be inspected flat on the bottom of the metal base box 601. Then start the first wax dripping machine 201 to inject an appropriate amount of molten paraffin into the metal base box 601. By manually pressing down on the metal base box 601, the movable mounting stage 9 below is moved and pressed down, so that the metal base box 601 contacts the first freezing plate 401, ensuring that the paraffin initially embedded solidifies quickly, thereby fixing the position of the tissue block.
[0049] After the paraffin wax has solidified, the operator places a mesh cover 602 on top of the pre-frozen metal base box 601, and then starts the second wax dripping machine 202 to inject molten paraffin wax onto the mesh cover 602. The molten paraffin wax falls from the mesh into the metal base box 601 until it completely covers the tissue block, thus completing the complete embedding process. The mold that has completed embedding continues to move to the second freezing plate 402 for final freezing. After the paraffin wax at the connection between the grid cover 602 and the metal base box 601 has completely solidified, simply pull up the top of the grid cover 602 (which is not covered by paraffin wax) to detach the paraffin wax connecting the grid cover 602 from the metal base box 601, which facilitates the subsequent slicing process.
[0050] Specifically, the metal base box 601 has a groove in the middle for placing tissue blocks; the receiving plate 901 has a through hole that matches the groove in the middle of the metal base box 601, and then the groove of the metal base box 601 is matched with the through hole on the receiving plate 901. When it is necessary to solidify the paraffin wax in the groove of the metal base box 601, the metal base box 601 is manually pressed down, and the groove of the metal base box 601 passes through the through hole of the receiving plate 901 and contacts the first freezing plate 401, thereby achieving rapid cooling.
[0051] Specifically, the mesh cover 602 includes a main flow hole for dripping wax and several venting micro-holes for draining wax bubbles.
[0052] Specifically, the mesh cover 602 has a main flow hole at the position of the wax injection port of the wax injection device 2. The diameter of the main flow hole should be slightly larger than the diameter of the wax injection port (difference of 0.5-1mm), rather than equal to or smaller. This is specifically for "smoothly receiving wax liquid + avoiding air entrapment + preventing channel blockage", which can minimize the generation of air bubbles during the wax injection process. Specifically, the mainstream through-hole is an inverted cone shape (wider at the top and narrower at the bottom, with a taper of 15°-20°).
[0053] As one embodiment, the transport component 3 also includes a roadblock assembly 302, which is disposed below the second wax dripping machine 202 to block and position the moving embedding mold 6 on the roller 301 below the second wax dripping machine 202 for wax collection.
[0054] Specifically, the roadblock assembly 302 includes a drive motor, a rotating shaft, and a baffle; The drive motor is fixed above the worktable 1, and its output end is connected to the rotating shaft; The baffle is fixedly installed on the rotating shaft and can rotate vertically under the drive of the drive motor. It has a blocking station that is raised to block the embedding mold 6, and a passage station that is flattened to allow the embedding mold 6 to pass through.
[0055] When the embedding mold 6 has not yet undergone secondary wax injection, the roadblock assembly 302 is in standby mode, and the baffle is rotated to the lowered position; the surface of the baffle is perpendicular to the upper surface of the roller 301, forming an effective blocking surface; When the embedding mold 6 moves to the second wax dripping machine 202 station, the baffle remains vertical, accurately blocking and positioning the embedding mold 6; ensuring that the embedding mold 6 is precisely positioned directly below the second wax dripping machine 202.
[0056] When the embedding mold 6 is stably blocked in the predetermined position, the second wax dripping machine 202 is started to inject molten paraffin into the mold, completing the secondary wax injection operation and ensuring that the paraffin completely covers the tissue sample.
[0057] After the second wax injection is completed, the drive motor drives the baffle to flip forward and rotate 90 degrees to a horizontal position. The surface of the baffle is parallel to the upper surface of the roller 301, eliminating the obstruction. The embedding mold 6 is transported under the rotating roller 301.
[0058] After the embedding mold 6 passes through, the drive motor rotates in the opposite direction; the baffle returns to the vertical position, ready to receive the next embedding mold 6, and waits for the next work cycle.
[0059] Specifically, when the roadblock assembly 302 starts to block, the motor of the connecting roller 301 is turned off; when the roadblock assembly 302 stops blocking, the motor of the connecting roller 301 is turned on.
[0060] like Figure 1-11 As shown in the embodiment, a control method for a paraffin embedding device is disclosed. The control methods for paraffin embedding devices include the following: S1: Turn on the temperature control device 5. After reaching the appropriate temperature, place the embedding mold 6 containing the tissue block on the first freezing plate 401. Start the first wax dripping machine 201 to drip molten paraffin into the embedding mold 6 for preliminary embedding, and let the paraffin of the preliminary embedding solidify. S2: Then, the embedding mold 6, which has undergone preliminary embedding and freezing, is transferred to the starting end of the transport component 3, and the embedding mold 6 moves under the rotation of the roller 301. S3: When the embedding mold 6 moves to the bottom of the second wax dripping machine 202, it is blocked and positioned by the roadblock component 302. The second wax dripping machine 202 drips molten paraffin into the embedding mold 6 to complete the embedding. S4: When the molten paraffin added into the embedding mold 6 is completely embedded, the obstruction of the roadblock component 302 is removed. The fully embedded embedding mold 6 continues to move along the transport component 3 to its end and reaches the second freezing plate 402 for final freezing treatment. After the paraffin is completely solidified, the embedded embedding mold 6 is removed.
[0061] In step S2, the scattered wax droplets are caught by the wax collection box 8 located below the roller 301.
[0062] This invention ensures precise positioning of tissue blocks and uniform solidification of paraffin through a staged embedding and freezing process, effectively avoiding problems such as bubble generation and tissue displacement, and significantly improving production efficiency. It innovatively utilizes the waste heat from the refrigeration system to heat the paraffin, realizing energy recycling and greatly reducing energy consumption. At the same time, the modular design and the configuration of the 8-piece wax receiving box not only maintain a clean working environment but also reduce the difficulty of operation, making the entire embedding process more standardized and regulated.
[0063] Obviously, the above embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the implementation of the present invention. Those skilled in the art can make other variations or modifications based on the above description. It is neither necessary nor possible to exhaustively describe all embodiments here. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention should be included within the scope of protection of the claims of the present invention.
Claims
1. A paraffin embedding device for pathological sections, characterized in that, include: Workbench (1), wax filling device (2), transport components (3), freezing table (4), temperature control equipment (5) and embedding mold (6); The workbench (1) is provided with a wax cavity (101), the freezing stage (4) and the transport component (3) are arranged on the workbench (1), and the wax cavity (101) is connected to the wax filling device (2). The wax-filling device (2) includes a first wax-drip machine (201) and a second wax-drip machine (202), and the freezing table (4) includes a first freezing plate (401) and a second freezing plate (402). The first freezing plate (401) is placed below the first wax dripping machine (201) and is used to initially embed the tissue block of the embedding mold (6) and freeze it; The second wax dripping machine (202) is positioned above the transport component (3) and is used to completely embed the initially embedded tissue block; The transport component (3) is provided with a second freezing plate (402) at its end, which is used to perform final freezing treatment on the embedding mold (6) of the completely embedded tissue block on the second freezing plate (402); The refrigeration section of the temperature control device (5) is connected to the freezing stage (4), and its heating section is connected to the wax chamber (101).
2. The paraffin embedding device for pathological sections according to claim 1, characterized in that, The temperature control device (5) includes a compressor (501), a condenser coil (502), a throttling mechanism (503), and an evaporator coil (504); the outlet of the compressor (501) is connected to the condenser coil (502), and the condenser coil (502) is connected to the evaporator coil (504) through the throttling mechanism (503); part of the condenser coil (502) is disposed in the wax cavity (101) to provide heat to the wax cavity (101); the evaporator coil (504) is disposed in close contact with the freezing stage (4) to cool the freezing stage (4) so that the wax in the embedding mold (6) solidifies.
3. The paraffin embedding device for pathological sections according to claim 2, characterized in that, The workbench (1) is also provided with a heat dissipation cavity (102), and some of the condensing coils (502) are also provided in the heat dissipation cavity (102). The heat dissipation cavity (102) is provided with convection openings and heat exchange is carried out by a fan (7).
4. The paraffin embedding device for pathological sections according to claim 3, characterized in that, The workbench (1) is also provided with a moving trough (103). The transport component (3) includes several rollers (301). The several rollers (301) are arranged in a row on the moving trough (103). The rollers (301) are also connected to a motor to enable the embedding mold (6) to be automatically transported along the rows of rollers (301).
5. The paraffin embedding device for pathological sections according to claim 4, characterized in that, The bottom of the moving groove (103) can also be detachably provided with a wax receiving box (8), which is located below the roller (301) and is used to receive the wax droplets scattered during the embedding process.
6. The paraffin embedding device for pathological sections according to claim 5, characterized in that, The transport component (3) also includes a roadblock assembly (302), which is located below the second wax dripping machine (202) to block and position the embedding mold (6) moving on the roller (301) below the second wax dripping machine (202) for wax collection.
7. The paraffin embedding device for pathological sections according to claim 1, characterized in that, The first freezing plate (401) is also provided with a movable mounting platform (9) for placing the embedding mold (6), the movable mounting platform (9) includes a receiving plate (901), a spring frame (902) and a spring frame (903). The elastic frame (902) is disposed at the bottom of the support plate (901) and is used to provide a restoring force when the support plate (901) moves downward; The receiving plate (901) is positioned above the first freezing plate (401) via the spring frame (903).
8. The paraffin embedding device for pathological sections according to claim 1, characterized in that, The embedding mold (6) includes a metal base box (601) for embedding pathological sections and a mesh cover (602); the mesh cover (602) can be fitted over the metal base box (601).
9. A control method using the paraffin embedding apparatus of claim 6, characterized in that, The control method for the paraffin embedding device includes the following: S1: Turn on the temperature control device (5). After reaching the appropriate temperature, place the embedding mold (6) carrying the tissue block on the first freezing plate (401). Start the first wax dripping machine (201) to drip molten paraffin into the embedding mold (6) for preliminary embedding. At the same time, the temperature control device (5) cools the first freezing plate (401) to solidify the paraffin that has been initially embedded. S2: Then, the embedding mold (6) after preliminary embedding and freezing is transferred to the starting end of the transport component (3), and the embedding mold (6) moves under the rotation of the roller (301); S3: When the embedding mold (6) moves to the bottom of the second wax dripping machine (202), it is blocked and positioned by the roadblock assembly (302), and the second wax dripping machine (202) drips molten paraffin into the embedding mold (6) to complete the embedding; S4: When the molten paraffin dripped into the embedding mold (6) is completely embedded, the obstruction of the roadblock assembly (302) is removed, and the fully embedded embedding mold (6) continues to move along the transport component (3) to its end and reaches the second freezing plate (402) for final freezing treatment; after the paraffin is completely solidified, the embedded mold (6) is removed.
10. The paraffin embedding device for pathological sections according to claim 9, characterized in that, In step S2, the scattered wax droplets are caught by the wax collection box (8) located below the roller (301).