Smear device capable of adjusting thickness of blood cells

Abstract

The invention relates to the technical field of smears, in particular to a smear device capable of adjusting the thickness of blood cells, which comprises a slide placing seat, the slide placing seat is provided with at least one slide placing groove used for placing a slide, and the upper side of the slide is provided with a positioning groove; the slide pushing mechanism comprises a slide pushing seat and a driving mechanism, the slide pushing seat is provided with at least one pushing slide, the pushing slide is obliquely arranged relative to the slide placing groove, and the driving mechanism comprises a linear module and is used for driving the slide pushing seat to move in the length direction of the slide placing groove. The positioning groove is ingeniously formed in the upper side of the slide, a drop of sample can be dropped into the positioning groove, the positioning groove plays a positioning role, and it is guaranteed that the sample adding positions are consistent and more accurate every time; and the sample adding operation is easier. The positioning groove further has the function of diffusing the sample towards the edges of the two sides when the positioning groove is matched with the bottom of the push piece, and a diffusion forming area is limited. The variable frequency motor is adopted, so that the smear pushing speed can be adjusted, and the smear thickness is changed.

Description

Technical Field

[0001] This invention relates to the field of smear technology, and more specifically to a smear device with adjustable blood cell thickness. Background Technology

[0002] Microscopic examination of blood smears is a fundamental and widely used method in hematological cytology. It is typically prepared manually by pushing the slide. A drop of blood is placed at one end of a glass slide. The slide is held in the left hand, while the right hand uses the smooth-edged end of a pusher to move from in front of the blood drop until it touches the drop. The blood drop then spreads along the pusher. The pusher is then moved smoothly forward at a 30-45 degree angle to the slide, leaving a thin film of blood on the slide.

[0003] Manual preparation methods are inefficient and labor-intensive for medical workers. Patent application CN 115683776 A discloses a blood smear device that can automate smear preparation, but its structure is relatively complex. Furthermore, the placement of blood drops on the slide is inconsistent for each application, affecting the final smear quality. Summary of the Invention

[0004] The purpose of this invention is to provide a smear device with adjustable blood cell thickness to solve the aforementioned technical problems.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] An adjustable blood cell smear device includes a slide holder with at least one slide placement groove for placing a slide, and a positioning groove on the upper side of the slide. The slide pushing mechanism includes a slide pushing seat and a driving mechanism. The slide pushing seat is provided with at least one slide, which is inclined relative to the slide placement groove. The driving mechanism includes a linear module for driving the slide pushing seat to move along the length direction of the slide placement groove.

[0007] Furthermore, the positioning groove is a semi-circular groove.

[0008] Furthermore, the positioning grooves are symmetrically arranged about the center line of the glass slide along its length.

[0009] Furthermore, one end of the slide placement groove is provided with a through-hole, and the tail of the slide is located at the through-hole.

[0010] Furthermore, the bottom of the pusher is a blood-scraping part, and the upper part is hinged to the pusher seat.

[0011] Furthermore, the front side of the push plate seat is provided with a hinge interface, the upper part of the push plate is provided with a hinge shaft, and a torsion spring is sleeved on the hinge shaft.

[0012] Furthermore, the upper part of the pusher is provided with a limiting part, which cooperates with the pusher seat to limit the angle of the pusher flipping downward, and the torsion spring is used to apply a force to the pusher to flip downward.

[0013] Furthermore, the linear module includes a linear motion part and a support part, the linear motion part is connected to the push plate seat, and the linear motion part and the support part are slidably engaged; the drive mechanism also includes a lifting mechanism, the lifting mechanism includes a lifting motion part, and the support part is connected to the lifting motion part.

[0014] Furthermore, a support member is provided on one side of the glass slide placement groove, and a wiping member is provided on the support member for wiping the slide after it is moved to a set position. The wiping member is pressed in place by a clamping member.

[0015] Furthermore, a disposable sleeve is fitted onto the pusher plate.

[0016] The beneficial effects of this invention are: This invention relates to an adjustable blood cell smear device. After the slide is placed and the test sample is added, the smear is automatically completed using a slide-pushing mechanism, resulting in high efficiency. A cleverly designed positioning groove is located on the upper side of the slide. When medical personnel add samples, such as blood cells / bone marrow cells, to the slide, a drop can be placed into the positioning groove. The groove acts as a positioning point, ensuring consistent and precise sample placement each time. This smearing operation is easier and reduces the workload of medical personnel. Additionally, when used in conjunction with the bottom of the slide pusher, it allows the sample to diffuse to the edges, defining the diffusion area. The semi-circular positioning groove ensures that one end of the final smear is tongue-shaped.

[0017] The linear module uses a motor with frequency conversion function, which can change the moving speed of the pusher. Different pusher speeds can be used for different samples dropped into the positioning groove. The pusher speed can also change the final coating thickness, thus achieving adjustability.

[0018] Furthermore, by designing a wiping area for wiping the pusher or by directly covering the pusher with a disposable sleeve, the problem of cross-infection during the use of the pusher can be solved. Attached Figure Description

[0019] Figure 1 This is a perspective view of Embodiment 1 of the adjustable blood cell thickness smear device of the present invention; Figure 2 This is an internal structural diagram of the blood cell thickness adjustable smear device of the present invention; Figure 3 This is a structural diagram of a glass slide holder (showing a glass slide); Figure 4 This is a structural diagram of the pusher holder and the pusher assembly; Figure 5 yes Figure 4 Another view of the structure shown; Figure 6 This is a perspective view of Embodiment 2 of the adjustable blood cell thickness smear device of the present invention; Figure 7 This is a schematic diagram showing the cooperation between the slide holder and the slide pusher; Figure 8 This is a structural diagram of the clamping component.

[0020] 1. Housing; 2. Slide holder; 21. Slide slot; 22. Clearance opening; 3. Slide; 31. Positioning slot; 4. Pusher; 41. Limiting part; 42. Hinge shaft; 43. First torsion spring; 44. Torsion spring shaft; 45. Second torsion spring; 5. Pusher seat; 51. Inclined surface; 61. First servo motor; 62. Linear motion part; 63. Connecting arm; 64. Support part; 71. Second servo motor; 72. Lifting motion part; 73. Fixing frame; 81. Wiping component; 82. Support component; 83. Pressing component; 831. Pressing part; 832. Pressing groove part; 9. Support frame. Detailed Implementation

[0021] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention are within the scope of protection of the present invention.

[0022] Embodiment 1 of the present invention: like Figures 1-5 As shown, the blood cell smear device with adjustable thickness includes a slide holder 2, the slide holder 2 having at least one slide placement groove 21 for placing a slide 3, and a positioning groove 31 on the upper side of the slide 3. The slide pushing mechanism includes a slide pushing seat 5 and a driving mechanism. The slide pushing seat 5 is provided with at least one slide 4, which is inclined relative to the slide placement groove 21 at an angle between 30° and 60°. The driving mechanism includes a linear module for driving the slide pushing seat 5 to move along the length direction of the slide placement groove 21.

[0023] In this embodiment, the slide holder 2 has four slide placement slots 21 arranged side by side, which can hold four slides 3 simultaneously. The slide holder 2 is located outside the housing 1, and a support frame 9 is provided inside the housing 1. The slide holder 2 is fixed to the upper part of the support frame 9 by screws. The slide pusher 5 is located outside the housing 1, and the main part of the drive mechanism is located inside the housing 1.

[0024] One end of the slide placement slot 21 is provided with a vertical clearance opening 22, and the tail of the slide 3 is located at the clearance opening 22, which makes it easy to hold the tail of the slide 3 by hand for placing or removing the slide.

[0025] The placement groove is approximately a rectangular groove in which the glass slide is placed.

[0026] The positioning groove 31 is a semi-circular groove located near the tail of the slide. The positioning groove 31 is symmetrically arranged about the center line of the slide's length. The orientation of the positioning groove 31 is defined as follows: the top center position of the positioning groove 31 is near the tail of the slide, meaning the opening of the positioning groove 31 faces the front of the slide. This orientation cannot be reversed. When medical personnel add samples to the slide, such as blood cells / bone marrow cells, a drop can be placed into the positioning groove 31. The positioning groove 31 serves a positioning function, ensuring consistent sample placement each time, resulting in more accurate placement; it also facilitates sample addition and reduces the workload of medical personnel.

[0027] The bottom of the pusher 4 is for scraping blood, and the upper part is hinged to the front of the pusher base 5. The front of the pusher base 5 is provided with a hinge interface, and the upper part of the pusher 4 passes through a hinge shaft 42. A first torsion spring 43 is sleeved on the hinge shaft 42. The two free ends of the first torsion spring 43 abut against the pusher base 5 and the pusher 4, respectively.

[0028] The upper part of the pusher plate 4 is also provided with a limiting part 41, which cooperates with the inclined surface 51 at the bottom of the pusher plate seat 5 to limit the angle of the pusher plate flipping downward. The first torsion spring 43 is used to apply a downward flipping force to the pusher plate.

[0029] The linear module includes a linear actuator 62 and a support 64. The linear actuator 62 is connected to the pusher seat 5, and the linear actuator 62 and the support 64 are slidably coupled. The support 64 is provided with a horizontally arranged transverse slide rail. The linear module adopts the principle of a lead screw and nut mechanism. The linear actuator 62 forms the nut in the lead screw and nut mechanism. The lead screw in the lead screw and nut mechanism is driven by an adjustable speed motor, which is mounted on the support 64. A connecting arm 63 is also located on one side of the linear actuator 62 for connecting to and supporting the pusher seat 5.

[0030] The motor can be a servo motor, referred to as the first servo motor 61, which has a frequency conversion function. When needed, the moving speed of the linear motion part 62 can be adjusted, thereby changing the moving speed of the pusher seat 5. For samples of different concentrations dropped into the positioning groove 31, different pusher speeds can be used, and the speed of pusher can also change the final coating thickness.

[0031] The drive mechanism also includes a lifting mechanism, which comprises a lifting action part 72. The support part 64 is connected to the lifting action part 72. The lifting mechanism can drive the linear module to lift and adjust. The lifting mechanism also adopts the principle of a lead screw and nut mechanism. The second servo motor 71 drives the lead screw to move, which in turn drives the lifting action part 72 (as the nut in the lead screw mechanism) to perform lifting and lowering actions. The lifting action part 72 is located on one side of the fixed frame 73. The fixed frame 73 is vertically equipped with a slide rail for the sliding assembly of the lifting action part 72.

[0032] The working principle of an adjustable blood cell smear device: Place one slide in each slide placement slot 21, ensuring the slide is oriented with the tail facing outwards and the positioning slot 31 side facing upwards. After placement, add a drop of blood cells / bone marrow cells to the positioning slot 31 of each slide. The height of the slide pusher 4 is controlled by the lifting mechanism, ensuring the bottom of the slide pusher 4 adheres to the upper side of the slide. Driven by the linear module, the slide pusher 4 moves forward. When the bottom of the slide pusher 4 reaches the positioning slot 31, it pauses for 0.1-5 seconds. During this time, the blood cells / bone marrow cells in the positioning slot 31 will rapidly spread along the edge of the bottom of the slide pusher 4. The aforementioned pause time can be 0.5 seconds to improve efficiency while meeting functional requirements. The slide pusher 4 continues to be pushed at a uniform speed along the slide surface to the tail of the slide, thus spreading the blood cells / bone marrow cells into a thin smear. After completion, the lifting mechanism raises the slide pusher 4 to a certain height, detaches it from the slide, and then retracts to its original position, awaiting the next slide push.

[0033] The semi-circular positioning groove 31 not only positions the dropped sample, but also allows the sample to spread to both sides when it is engaged with the bottom of the pusher 4, while defining the diffusion area; the semi-circular positioning groove 31 makes one end of the final smear tongue-shaped.

[0034] In other embodiments, when the number of slides is small, a manual slide pushing method can also be used. That is, the drive mechanism is not activated, a drop of blood cells / bone marrow cells is dropped into the positioning groove of the slide, and another clean slide is used as the pusher. The slide is tilted at an angle of 30 to 60 degrees and the movement of the clean slide is manually controlled, which replaces the pusher automatically controlled by the linear module.

[0035] Example 2 of the present invention: an adjustable blood cell smear device The difference from Embodiment 1 is the addition of a wiping area. A support member 82 is provided on one side of the slide placement slot; two members can be installed as a single unit or separately. A wiping member 81 is provided on the support member 82. The support member 82 is elongated and has a conical protrusion at its upper part. The wiping member 81 is a disposable alcohol towel, laid on both sides of the upper part of the support member 82, and is pressed in place by a clamping member 83. It is used to wipe the slide after it has moved to a set position, i.e., to wipe the slide after each use to reduce cross-contamination.

[0036] The clamping member 83 includes a hinge, a pressing part 831, and a pressing groove 832, with an overall approximately T-shaped structure. The hinge is connected to a torsion spring shaft 44, which is equipped with a second torsion spring 45. The torsion spring shaft 44 can be connected to the side wall of the slide placement groove 2. The pressing groove 832 has an opening facing the direction of the groove, which is adapted to the shape of the upper part of the support member 82 and can be fastened onto it. Under the action of the second torsion spring 45, the pressing groove 832 of the clamping member 83 can maintain the tendency to press the wiping member 81. When it is necessary to replace the wiping member 81, the pressing part is pressed down to overcome the force of the second torsion spring 45, the clamping member 83 rotates and releases, and the wiping member 81 can be removed and replaced with a new wiping member.

[0037] In other embodiments, the wiping area described above is not provided. Instead, a disposable sleeve is directly placed on each of the pushers. The disposable sleeve is a consumable that is discarded after use and replaced with a new one.

Claims

1. A smear device with adjustable blood cell thickness, characterized in that: Includes a slide holder, the slide holder having at least one slide placement groove for placing a slide, and a positioning groove provided on the upper side of the slide; The slide pushing mechanism includes a slide pushing seat and a driving mechanism. The slide pushing seat is provided with at least one slide, which is inclined relative to the slide placement groove. The driving mechanism includes a linear module for driving the slide pushing seat to move along the length direction of the slide placement groove.

2. The adjustable blood cell thickness smear device according to claim 1, characterized in that: The positioning groove is a semi-circular groove.

3. The adjustable blood cell thickness smear device according to claim 2, characterized in that: The positioning grooves are symmetrically arranged about the center line of the glass slide along its length.

4. The adjustable blood cell thickness smear device according to claim 1, characterized in that: One end of the slide placement slot is provided with a through clearance opening, and the tail of the slide is located at the clearance opening.

5. The adjustable blood cell thickness smear device according to claim 1, characterized in that: The bottom of the pusher is the blood-scraping part, and the upper part is hinged to the pusher seat.

6. The adjustable blood cell thickness smear device according to claim 5, characterized in that: The front side of the push plate seat is provided with a hinge interface, and the upper part of the push plate is provided with a hinge shaft, on which a torsion spring is sleeved.

7. The adjustable blood cell thickness smear device according to claim 5, characterized in that: The upper part of the pusher is also provided with a limiting part, which cooperates with the pusher seat to limit the angle of the pusher flipping downward. The torsion spring is used to apply a force to the pusher to flip downward.

8. The adjustable blood cell thickness smear device according to claim 1, characterized in that: The linear module includes a linear actuator and a support. The linear actuator is connected to the push plate holder. The support part slides in conjunction with the drive mechanism, which also includes a lifting mechanism, and the support part is connected to the lifting mechanism.

9. The adjustable blood cell thickness smear device according to any one of claims 1 to 8, characterized in that: A support member is provided on one side of the glass slide placement slot, and a wiping member is provided on the support member for wiping the slide after it is moved to a set position. The wiping member is pressed in place by a clamping member.

10. The adjustable blood cell thickness smear device according to any one of claims 1 to 8, characterized in that: The pusher is fitted with a disposable sleeve.

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