Minimally invasive delivery device for tissue patch

Abstract

The invention relates to the technical field of interventional medical instruments, in particular to a minimally invasive delivery device for tissue patches. A minimally invasive delivery device for a tissue patch includes a delivery catheter, a push rod, and an umbrella-shaped stent. The pushing rod is arranged in the delivery catheter in a sliding and penetrating mode. The umbrella-shaped support comprises a base and a supporting wire, and the base is connected with one end of the pushing rod. The multiple supporting wires are arranged, one end of each supporting wire is connected with the base, and the multiple supporting wires are distributed around the base at intervals. The umbrella-shaped support is made of shape memory materials, and the end, away from the base, of the supporting wire is used for being inserted into a limiting sleeve on the edge of a tissue patch. The umbrella-shaped support has a first contraction state, an unfolding state and a second contraction state. The tissue patch can be flatly spread in the cavity operation process, and the tissue patch can be stably fixed and is not prone to displacement when the delivery device retracts.

Description

Technical Field

[0001] This invention relates to the field of interventional medical device technology, and more specifically, to a minimally invasive delivery device for tissue patches. Background Technology

[0002] In the field of interventional medical devices, tissue patches are biocompatible functional implantable devices, usually made of bioactive materials or composite materials. They can be attached to the surface of damaged tissues in human cavities to achieve functions such as wound closure, hemostasis, tissue repair, or targeted delivery of therapeutic factors. They are widely used in interventional treatment of cavities-related diseases such as cardiovascular, digestive, and respiratory diseases, and are one of the key components for tissue repair in interventional treatment.

[0003] In intracavitary interventional surgery, tissue patches are precisely delivered to the target lesion site using a delivery device. The core technical requirements are ensuring the tissue patch spreads evenly within the cavity and that it does not easily shift during the withdrawal of the delivery device. Even spreading is a prerequisite for ensuring proper adhesion to the damaged tissue and maximizing therapeutic efficacy. Uneven spreading can lead to excessive gaps in the adhesion, causing problems such as bleeding, infection, or poor repair. Preventing the patch from shifting during withdrawal avoids deviation from the lesion site, ensuring treatment precision and reducing the risk of secondary damage.

[0004] Current tissue patch delivery devices still have significant shortcomings. Under the complex physiological environment and dynamic mechanical forces of cavities, it is difficult to achieve stable and smooth patch spreading, leading to wrinkles and curling. Furthermore, when the delivery device is withdrawn, the friction between the patch and the device can easily cause patch displacement, resulting in treatment failure and failing to meet the core technical requirements of clinical interventional therapy. Therefore, how to achieve smooth spreading of tissue patches during cavity operations and stable fixation of the patch without displacement when the delivery device is withdrawn has become an urgent technical problem to be solved in this field. Summary of the Invention

[0005] To address the challenges of achieving smooth spreading of tissue patches during intracavitary procedures and ensuring stable fixation and minimal displacement of the patches during retraction of the delivery device, this invention provides a minimally invasive delivery device for tissue patches, comprising:

[0006] A delivery catheter, wherein the delivery catheter has a hollow structure;

[0007] A push rod, which is slidably inserted into the delivery conduit;

[0008] An umbrella-shaped support includes a base and support wires; the base is connected to one end of a push rod; multiple support wires are provided; one end of each support wire is connected to the base; the multiple support wires are distributed at intervals around the base; the umbrella-shaped support is made of shape memory material; the end of each support wire away from the base is used to insert a limiting sleeve at the edge of a tissue patch;

[0009] The umbrella-shaped support has a first retracted state, an expanded state, and a second retracted state.

[0010] In the first contracted state, the umbrella-shaped support retracts into the delivery conduit, and the multiple support wires wrap around the push rod;

[0011] In the unfolded state, the umbrella-shaped support is located outside the delivery conduit. When the umbrella-shaped support is within the body temperature range of the organism, the multiple support wires unfold into a disc-shaped memory shape in a direction away from the push rod.

[0012] In the second contracted state, the umbrella-shaped support retracts into the delivery conduit, and the support wire extends away from the push rod.

[0013] Optionally, when the umbrella-shaped support is in the memory shape, multiple support wires are distributed on a first conical surface with the base as the vertex, and the diameter of the first conical surface gradually increases in the direction away from the push rod.

[0014] Optionally, the diameter of the support wire gradually decreases from one end connected to the base to the other end.

[0015] Optionally, one end of the support wire is rotatably connected to the base about a first axis; the first axis is perpendicular to the support wire; the first axis is perpendicular to the push rod.

[0016] Optionally, one end of the support wire is fixedly connected to the base.

[0017] Optionally, the umbrella-shaped support further includes a bent locking hook; one end of the locking hook is connected to the base, and the other end is used to slide through the positioning sleeve on the tissue patch; the minimally invasive delivery device for the tissue patch further includes an unlocking module; the unlocking module is used to drive the locking hook to disengage from the positioning sleeve; the unlocking module is connected to the push rod.

[0018] Optionally, one end of the locking hook is fixedly connected to the base; the locking hook is elastic.

[0019] Optionally, the unlocking module includes a pull wire and a drive unit; the drive unit is slidably connected to the delivery conduit along the axis of the delivery conduit; the push rod has a hollow interior forming a wire hole; the pull wire passes through the wire hole; one end of the pull wire is connected to the lock hook, and the other end is connected to the drive unit.

[0020] Optionally, the wire hole is parallel to the axis of the push rod and has a gap between them.

[0021] Optionally, the drive unit includes a turntable and a rotating sleeve; the rotating sleeve is rotatably connected to the delivery conduit coaxially; the turntable and the rotating sleeve are slidably connected along the axis of the rotating sleeve; the turntable is fixedly connected to the push rod; and the push rod is rotatably connected to the delivery conduit.

[0022] Optionally, the unlocking module further includes a reset elastic element; the reset elastic element is connected between the delivery conduit and the driving part; the reset elastic element is used to drive the driving part to move and reset toward the umbrella-shaped bracket.

[0023] To address the challenges of achieving smooth spreading of tissue patches during cavity manipulation and ensuring stable fixation and minimal displacement of the patches during delivery device retraction, this invention offers the following advantages:

[0024] The framework formed by multiple support wires in the umbrella-shaped scaffold ensures the flatness of the tissue patch during unfolding. Furthermore, the sliding arrangement between the push rod and the delivery catheter, as well as the sliding insertion of the support wires into the limiting sleeve at the upper edge of the tissue patch, allows the operator to pull the push rod, and with the limiting effect of the umbrella-shaped scaffold at the end of the delivery catheter on the diameter, the support wires retract and smoothly detach from the patch, reducing the risk of tissue patch displacement. Therefore, this invention achieves the effect of flat unfolding of the tissue patch and minimal displacement. Attached Figure Description

[0025] Figure 1 A schematic diagram of a minimally invasive delivery device for tissue patches according to one embodiment is shown;

[0026] Figure 2 It shows Figure 1 Enlarged schematic diagram of point A in the minimally invasive delivery device used for tissue patches;

[0027] Figure 3 A schematic diagram showing the connection relationship between a tissue patch and an umbrella-shaped support in an unfolded state according to one embodiment is shown.

[0028] Figure 4 It shows Figure 3 A front view of the connection between the tissue patch and the unfolded umbrella-shaped support.

[0029] Figure 5 A simplified schematic diagram shows a tissue patch and an umbrella-shaped scaffold in its first contracted state contracted within a delivery catheter;

[0030] Figure 6 A simplified schematic diagram shows the umbrella-shaped stent retracted within the delivery catheter in its second contracted state.

[0031] Figure label:

[0032] 10. Delivery catheter; 20. Push rod; 30. Umbrella-shaped support; 31. Base; 32. Support wire; 40. Locking hook; 50. Unlocking module; 51. Pull wire; 52. Drive unit; 521. Turntable; 522. Rotating sleeve; 60. Tissue patch; 61. Patch body; 62. Limiting sleeve; 63. Positioning sleeve. Detailed Implementation

[0033] The present disclosure will now be discussed with reference to several exemplary embodiments. It should be understood that these embodiments are discussed only to enable those skilled in the art to better understand and thus implement the present disclosure, and are not intended to imply any limitation on the scope of the disclosure.

[0034] As used herein, the term "comprising" and its variations are to be interpreted as open-ended terms meaning "including but not limited to". The term "based on" is to be interpreted as "at least partially based on". The terms "one embodiment" and "an embodiment" are to be interpreted as "at least one embodiment". The term "another embodiment" is to be interpreted as "at least one other embodiment". The terms "upper", "lower", "left", "right", "front", "rear", "top", "bottom", "inner", "outer", "vertical", "horizontal", "lateral", "longitudinal", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings. These terms are primarily for the purpose of better describing this application and its embodiments and are not intended to limit the indicated devices, elements, or components to having a specific orientation or being constructed and operated in a specific orientation. Furthermore, some of the above terms may be used to indicate other meanings besides orientations or positional relationships; for example, the term "upper" may in some cases indicate a dependency or connection relationship. Those skilled in the art can understand the specific meaning of these terms in this application according to the specific circumstances. In addition, the terms "installed", "set up", "equipped with", "connected", and "linked" should be interpreted broadly. For example, it can be a fixed connection, a detachable connection, or an integral structure; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or an internal connection between two devices, elements, or components. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances. Furthermore, the terms "first," "second," etc., are mainly used to distinguish different devices, elements, or components (the specific types and structures may be the same or different), and are not used to indicate or imply the relative importance or quantity of the indicated devices, elements, or components. Unless otherwise stated, "a plurality of" means two or more.

[0035] Reference Figure 1 , Figure 2 and Figure 3 To address the issues of ensuring the smooth spreading of the tissue patch 60 during cavity operations and the stable fixation and non-displacement of the tissue patch 60 when the delivery device is withdrawn, this embodiment provides a minimally invasive delivery device for the tissue patch 60, including a delivery catheter 10, a push rod 20, and an umbrella-shaped support 30.

[0036] Reference Figure 1 , Figure 2 and Figure 3The delivery catheter 10 has a hollow structure to accommodate the push rod 20, the umbrella-shaped support 30, and the tissue patch 60 attached to the umbrella-shaped support 30. Under real-time monitoring guided by medical imaging, the doctor precisely delivers the distal end of the delivery catheter 10 into the body cavity of the target lesion area via skin puncture, preparing for the subsequent release and spreading of the tissue patch 60. The distal end of the delivery catheter 10 is also the end used to deliver the tissue patch 60. The target lesion area is the target zone.

[0037] Preferably, the delivery catheter 10 is made of medical-grade nylon material, which has excellent biocompatibility and flexibility, and can conform to the direction of the cavity to avoid damage; the outer surface of the catheter is coated with a hydrophilic lubricating coating with a friction coefficient of less than or equal to 0.05, which can significantly reduce the resistance to pushing and retracting, prevent the patch from shifting or wrinkling as much as possible, and ensure that the patch is laid flat.

[0038] Reference Figure 1 The push rod 20 is coaxially arranged with the delivery conduit 10, and the push rod 20 slides through the delivery conduit 10. One end of the push rod 20 is connected to the umbrella-shaped support 30.

[0039] Preferably, the push rod 20 can be made of stainless steel. Stainless steel has high hardness and rigidity, and is not easily bent or deformed during the push process. It can accurately transmit the pushing force and ensure that the tissue patch 60 is stably pushed to the target area of ​​the cavity within the slender delivery catheter 10, avoiding patch delivery jamming and positional deviation caused by deformation of the push rod 20. Medical stainless steel meets the biocompatibility requirements of interventional medical devices, has no obvious cytotoxicity or sensitization, and will not cause adverse reactions when in contact with human tissue and tissue patch 60, making it suitable for the complex physiological environment within the cavity.

[0040] Reference Figure 3 and Figure 4 The patch 60 includes a patch body 61, a limiting sleeve 62, and a positioning sleeve 63; multiple limiting sleeves 62 are distributed along the edge contour of the patch body 61; the positioning sleeve 63 is located at the center of the patch body 61. The patch body 61 is fixedly connected to the limiting sleeve 62 and the positioning sleeve 63 respectively, and the patch body 61 can be integrally formed with the limiting sleeve 62 and the positioning sleeve 63 respectively.

[0041] Reference Figure 2 , Figure 3 and Figure 4The umbrella-shaped support 30 includes a base 31 and support wires 32. The base 31 is connected to one end of the push rod 20. Multiple support wires 32 are provided, with one end connected to the base 31, and the multiple support wires 32 are spaced apart around the base 31. The ends of the support wires 32 away from the base 31 are used to insert into the limiting sleeves 62 at the edge of the tissue patch 60. The umbrella-shaped support 30 is made of shape memory material. Optionally, the push rod 20 is fixedly connected to the base 31, and when the push rod 20 is pulled or pushed, it can cause the multiple support wires 32 to unfold or retract in an umbrella shape.

[0042] Preferably, the umbrella-shaped opening and closing stent is fabricated using a nickel-titanium shape memory alloy through integrated laser cutting. This integrated laser cutting process ensures the structural integrity and dimensional accuracy of the umbrella-shaped stent 30, avoiding the stress concentration and easy breakage risks associated with spliced ​​structures, and improving the overall mechanical stability and service life of the stent. For example, the precise ratio of 55.8 wt% nickel and 44.2 wt% titanium in the nickel-titanium alloy not only ensures the alloy's excellent biocompatibility, preventing rejection reactions in the human body, but also endows the stent with good shape memory effect and elastic recovery ability, making it less prone to plastic deformation due to dynamic mechanical forces such as cavity compression and physiological activities. For example, the austenitic phase transformation end temperature of the umbrella-shaped stent 30 is set at 34°C, which forms a reasonable temperature difference with the physiological environment of 37°C in the human body. This allows the stent to fully and gradually unfold within 10 seconds after entering the human body. The unfolding process is smooth and gentle, and it is not easy to damage the inner wall of the cavity due to the impact force caused by instantaneous popping. At the same time, after unfolding, it can form a uniform and stable support force, closely fit the inner wall of the cavity and accurately support the tissue patch 60, and ensure that the tissue patch 60 is spread in all directions without wrinkles as much as possible. This provides reliable support for the full adhesion of the tissue patch 60 to the damaged tissue and further ensures the effectiveness of the treatment.

[0043] Reference Figure 4 , Figure 5 and Figure 6 The umbrella-shaped support 30 has a first contracted state, an expanded state, and a second contracted state.

[0044] Reference Figure 3 , Figure 4 and Figure 5 When the minimally invasive delivery device for the tissue patch 60 delivers the tissue patch 60 into the cavity, both the tissue patch 60 and the umbrella-shaped support 30 retract within the delivery catheter 10. At this time, the umbrella-shaped support 30 is in a first retracted state, as shown in the image. Figure 5 As shown. In the first contracted state, the umbrella-shaped stent 30 retracts into the delivery conduit 10, and multiple support wires 32 wrap around the push rod 20. At this time, the umbrella-shaped stent 30 can be considered to be approximately conical in shape.

[0045] Reference Figure 1 and Figure 3When the distal end of the delivery catheter 10 reaches the target area, the push rod 20 pushes the umbrella-shaped support 30 and the tissue patch 60 out of the distal end of the delivery catheter 10. The umbrella-shaped support 30 unfolds into an expanded state, as shown in the image. Figure 3 As shown. In the deployed state, the umbrella-shaped support 30 is located outside the delivery conduit 10. When the umbrella-shaped support 30 is within the body temperature range of the organism, multiple support wires 32 unfold in a disc-shaped memory shape away from the push rod. The disc shape can be planar or conical.

[0046] Reference Figure 3 , Figure 4 and Figure 6 After the tissue patch 60 has adhered to the target area, the push rod 20 is pulled back, causing the umbrella-shaped scaffold 30 to detach from the tissue patch 60 and eventually retract back into the delivery catheter 10. At this time, the umbrella-shaped scaffold 30 is in a second retracted state, as shown in the image. Figure 6 As shown. In the second contracted state, the umbrella-shaped support 30 retracts into the delivery conduit 10, and the support wire 32 extends away from the push rod 20. At this time, the umbrella-shaped support 30 can be considered to be approximately inverted conical in shape. The apex of the conical shape in the first contracted state and the inverted conical shape in the second contracted state face opposite directions.

[0047] This embodiment utilizes multiple support wires 32 within the umbrella-shaped support 30 as a framework for the unfolding of the tissue patch 60, ensuring the flatness of the tissue patch 60 within the cavity as much as possible. Furthermore, the sliding arrangement between the push rod 20 and the delivery catheter 10, and the sliding insertion arrangement between the support wires 32 and the limiting sleeve 62 at the upper edge of the tissue patch 60, allow the operator to pull the push rod 20, and with the limiting effect of the delivery catheter 10 on the diameter of the umbrella-shaped support 30, the support wires 32 can retract and smoothly detach from the patch, reducing the risk of tissue patch 60 displacement. Therefore, this embodiment achieves the effect of flat unfolding of the tissue patch 60 and minimal displacement.

[0048] Reference Figure 2 and Figure 4 Furthermore, when the umbrella-shaped support 30 is in its memory shape, multiple support wires 32 are distributed on a first conical surface with the base 31 as its apex. The diameter of the first conical surface gradually increases in the direction away from the push rod 20. The first conical surface is an inverted cone shape, such as... Figure 2 and Figure 4 The state shown in the figure. The umbrella-shaped support 30 with an inverted cone shape can ensure the firmness of the umbrella-shaped support 30 in pressing the tissue patch 60, disperse the pressing stress, avoid the loosening of the tissue patch 60 caused by uneven local pressure as much as possible, and reduce the risk of the tissue patch 60 edge lifting.

[0049] Reference Figure 2 and Figure 4Furthermore, the diameter of the support wire 32 gradually decreases from one end connected to the base 31 to the other. The end of the support wire 32 furthest from the base 31 is the distal end, which has a thinner diameter and is more flexible when returning to its memory shape. The end of the support wire 32 closest to the base 31 is the proximal end, which has a thicker diameter and returns to its memory shape more slowly than the distal end. This allows the support wire 32 to unfold gradually and gently from the distal end to the proximal end, minimizing the risk of the umbrella-shaped support 30 snapping open instantly. Therefore, the gradual and gentle unfolding method used in this embodiment is less likely to cause displacement or wrinkling of the tissue patch 60, and less likely to damage the fragile target tissue.

[0050] Reference Figure 3 Because the diameter of the support wire 32 is a gradually changing structure, the size design of the limiting sleeve 62 at the edge of the tissue patch 60 can be utilized. For example, the diameter at any point on the tissue patch 60 can be smaller than the sum of the lengths of the two support wires 32 positioned opposite each other at that location, thus limiting the length of the support wire 32 passing through the limiting sleeve 62. If the pushing rod 20 applies too much force when pushing the tissue patch 60 towards the target area, the multiple support wires 32 laid along the first conical surface will be bent due to the size limitation of the limiting sleeve 62, thereby increasing the resistance when pushing the rod 20. This avoids the multiple support wires 32 from completely adhering to the tissue patch 60 or being laid in an inverted conical shape. In other words, this embodiment can ensure the stability of the umbrella-shaped support 30 pressing the tissue patch 60 and reduce the risk of misoperation due to excessive force.

[0051] Reference Figure 2 , Figure 4 and Figure 6 Furthermore, one end of the support wire 32 is rotatably connected to the base 31 about a first axis; the first axis is perpendicular to the support wire 32; the first axis is perpendicular to the push rod 20. In this embodiment, due to the variable diameter design of the support wire 32 and the size restriction formed by the limiting sleeve 62, the rotatable connection between the support wire 32 and the base 31 is not likely to affect the structural stability of the umbrella-shaped support 30 in the unfolded state, that is, the structural stability of the first conical surface, as shown in the unfolded state. Figure 4 As shown, when the push rod 20 moves away from the target area to retract the push rod 20, since the support wire 32 is rotatably connected to the base 31, the support wire 32 is more easily retracted into the delivery conduit 10, forming a small-diameter, tapered inverted cone shape, reducing the difficulty of retrieving the umbrella-shaped support 30.

[0052] In another embodiment, one end of the support wire 32 is fixedly connected to the base 31. This fixed connection between the support wire 32 and the base 31 further improves the structural stability of the umbrella-shaped support 30's shape memory and reduces the risk of misoperation due to excessive force applied during the process of the push rod 20 pressing the umbrella-shaped support 30 against the tissue patch 60.

[0053] Reference Figure 3 and Figure 4 Furthermore, the umbrella-shaped support 30 also includes a bent locking hook 40, one end of which is connected to the base 31, and the other end is used to slide through the positioning sleeve 63 on the tissue patch 60. The minimally invasive delivery device for the tissue patch 60 also includes an unlocking module 50; the unlocking module 50 is used to drive the locking hook to disengage from the positioning sleeve 63; the unlocking module 50 is connected to the push rod 20. By locking the locking hook 40 to the tissue patch 60, the positioning accuracy between the center of the umbrella-shaped support 30 and the center of the tissue patch 60 can be ensured, improving the positioning accuracy of the tissue patch 60 in the target area and reducing the risk of tissue patch 60 displacement.

[0054] Reference Figure 3 and Figure 4 Furthermore, one end of the locking hook 40 is fixedly connected to the base 31; the locking hook 40 is elastic. The elasticity of the locking hook 40 can ensure the stable locking of the locking hook 40 and the positioning sleeve 63. The control unlocking module 50 drives the locking hook 40 to undergo elastic deformation to disengage from the positioning sleeve 63, which can efficiently complete the unlocking of the locking hook 40.

[0055] Reference Figure 1 , Figure 2 and Figure 3 Furthermore, the unlocking module 50 includes a pull wire 51 and a drive unit 52; the drive unit 52 is slidably connected to the delivery conduit 10 along the axis of the delivery conduit 10; the push rod 20 has a hollow interior forming a wire hole; the pull wire 51 passes through the wire hole; one end of the pull wire 51 is connected to the locking hook 40, and the other end is connected to the drive unit 52. By controlling the drive unit 52 to slide relative to the delivery conduit 10, the drive unit 52 drives the pull wire 51 to move, and the pull wire 51 pulls the locking hook 40, causing the locking hook 40 to undergo elastic deformation and thus disengage from the positioning sleeve 63.

[0056] Reference Figure 1 and Figure 3 Furthermore, the drive unit 52 is fixedly connected to the push rod 20. When the drive unit 52 slides, it can synchronously drive the push rod 20 to move, thereby enabling the locking hook 40 to be unlocked while the umbrella-shaped bracket 30 is simultaneously disengaged from the limiting sleeve 62 and finally retracted into the delivery tube 10, achieving efficient unlocking.

[0057] Reference Figure 1 and Figure 3 Furthermore, the wire hole is parallel to and spaced from the axis of the push rod 20. That is, the pull wire 51 is eccentrically positioned in the push rod 20, which allows the direction of force exerted by the pull wire 51 on the lock hook 40 to be kept at a certain distance from the center of the base 31, so that the pull wire 51 has a larger lever arm when pulling the lock hook 40, thus improving the smoothness of unlocking.

[0058] Reference Figure 1 , Figure 2 and Figure 3 Furthermore, the drive unit 52 includes a turntable 521 and a rotating sleeve 522; the rotating sleeve 522 is coaxially rotatably connected to the delivery catheter 10; the turntable 521 and the rotating sleeve 522 are slidably connected along the axis of the rotating sleeve 522; one end of the push rod 20 away from the umbrella-shaped support 30 is fixedly connected to the turntable 521; the push rod 20 is rotatably connected to the delivery catheter 10. Controlling the drive unit 52 to rotate relative to the delivery catheter 10 causes the drive unit 52 to rotate, which in turn causes the push rod 20 to rotate, which in turn causes the umbrella-shaped support 30 to rotate, which in turn causes the tissue patch 60 to rotate. Therefore, when the tissue patch 60 has an irregular contoured structure, it is easy to adjust the orientation of the tissue patch 60 by controlling the rotation of the drive unit 52, thereby achieving precise positioning of the tissue patch 60 in the target area.

[0059] In other embodiments, the drive unit 52 and the push rod 20 are slidably arranged along the axial direction of the push rod 20. The push rod 20 and the delivery catheter 10 can rotate and slide relative to each other, respectively operating the push rod 20 and the drive unit 52. This allows the steps of unlocking the locking hook 40 and retrieving the umbrella-shaped support 30 to be performed separately, reducing the risk of tissue patch 60 being easily displaced due to the simultaneous execution of multiple steps.

[0060] Furthermore, the unlocking module 50 also includes a reset elastic element; the reset elastic element is connected between the delivery catheter 10 and the drive unit 52; the reset elastic element is used to drive the drive unit 52 to move and reset towards the umbrella-shaped support 30. After the tissue patch 60 is delivered, during the retraction of the push rod 20, the reset elastic element drives the drive unit 52 to reset, which allows the locking hook 40 to reset quickly by its own elasticity, extending the service life of the locking hook 40 and facilitating the next delivery operation of the tissue patch 60.

[0061] This invention is compatible with conventional interventional catheters with an inner diameter of 2-8mm. The interventional catheter, also known as the delivery catheter 10, can complete the entire operation with only percutaneous minimally invasive puncture, without the need for open surgery, resulting in minimal trauma. It is widely compatible with the delivery of various medical tissue patches 60, such as vascular patches, myocardial regeneration patches, and tissue repair patches, and has a wide range of clinical applications.

[0062] Those skilled in the art will understand that the above embodiments are specific examples of implementing this disclosure, and in practical applications, various changes can be made in form and detail without departing from the scope of this disclosure.

Claims

1. A minimally invasive delivery device for tissue patches, characterized in that, The minimally invasive delivery device for tissue patches includes: A delivery catheter, wherein the delivery catheter has a hollow structure; A push rod, which is slidably inserted into the delivery conduit; An umbrella-shaped support includes a base and support wires; the base is connected to one end of a push rod; multiple support wires are provided; one end of each support wire is connected to the base; the multiple support wires are distributed at intervals around the base; the umbrella-shaped support is made of shape memory material; the end of each support wire away from the base is used to insert a limiting sleeve at the edge of a tissue patch; The umbrella-shaped support has a first retracted state, an expanded state, and a second retracted state. In the first contracted state, the umbrella-shaped support retracts into the delivery conduit, and the multiple support wires wrap around the push rod; In the unfolded state, the umbrella-shaped support is located outside the delivery conduit. When the umbrella-shaped support is within the body temperature range of the organism, the multiple support wires unfold into a disc-shaped memory shape in a direction away from the push rod. In the second contracted state, the umbrella-shaped support retracts into the delivery conduit, and the support wire extends away from the push rod.

2. The minimally invasive delivery device for tissue patches according to claim 1, characterized in that, When the umbrella-shaped support is in the memory shape, multiple support wires are distributed on a first conical surface with the base as the vertex, and the diameter of the first conical surface gradually increases in the direction away from the push rod.

3. The minimally invasive delivery device for tissue patches according to claim 2, characterized in that, The diameter of the support wire gradually decreases from one end connected to the base to the other end.

4. A minimally invasive delivery device for tissue patches according to claim 3, characterized in that, One end of the support wire is rotatably connected to the base about a first axis; the first axis is perpendicular to the support wire; the first axis is perpendicular to the push rod.

5. A minimally invasive delivery device for tissue patches according to claim 1, characterized in that, One end of the support wire is fixedly connected to the base.

6. A minimally invasive delivery device for tissue patches according to claim 1, characterized in that, The umbrella-shaped support also includes a bent locking hook; one end of the locking hook is connected to the base, and the other end is used to slide through the positioning sleeve on the tissue patch; the minimally invasive delivery device for the tissue patch also includes an unlocking module; the unlocking module is used to drive the locking hook to disengage from the positioning sleeve; the unlocking module is connected to the push rod.

7. A minimally invasive delivery device for tissue patches according to claim 6, characterized in that, One end of the locking hook is fixedly connected to the base; the locking hook is elastic.

8. A minimally invasive delivery device for tissue patches according to claim 6, characterized in that, The unlocking module includes a pull wire and a drive unit; the drive unit is slidably connected to the delivery conduit along the axis of the delivery conduit; the push rod has a hollow interior forming a wire hole; the pull wire passes through the wire hole; one end of the pull wire is connected to the lock hook, and the other end is connected to the drive unit.

9. A minimally invasive delivery device for tissue patches according to claim 8, characterized in that, The wire hole is parallel to the axis of the push rod and is spaced apart.

10. A minimally invasive delivery device for tissue patches according to claim 8, characterized in that, The drive unit includes a turntable and a rotating sleeve; the rotating sleeve is rotatably connected to the delivery conduit coaxially; the turntable and the rotating sleeve are slidably connected along the axis of the rotating sleeve; the turntable is fixedly connected to the push rod; and the push rod is rotatably connected to the delivery conduit.

11. A minimally invasive delivery device for tissue patches according to claim 8, characterized in that, The unlocking module further includes a reset elastic element; the reset elastic element is connected between the delivery conduit and the driving part; the reset elastic element is used to drive the driving part to move and reset toward the umbrella-shaped bracket.

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