An oil-controlling composition, its preparation method and application

Abstract

This invention provides an oil-controlling composition, its preparation method, and its application. The composition comprises extracts from *Eryngium sibiricum*, sunflower seed, *Edelweiss*, and *Saussurea involucrata*. Cosmetic products containing this composition exhibit excellent oil-controlling, moisturizing, and soothing / repairing effects.

Description

Cross-references to related applications

[0001] This application is a divisional application of application number 202311551603.6, filed on November 17, 2023, entitled "An oil-controlling composition, its preparation method and application", the contents of which are incorporated herein by reference in their entirety. Technical Field

[0002] This invention relates to the field of cosmetic technology, and more specifically, to an oil-controlling composition, its preparation method, and its application. Background Technology

[0003] Oily skin is caused by overactive sebaceous glands, and the characteristics of these glands are determined by genetic factors. Clinically, based on the amount of lipids on the skin surface, skin can be broadly classified into several types, including oily skin, dry skin, normal skin, and combination skin. People with oily skin have overactive sebaceous glands, resulting in a greasy face that is difficult to clean and has an unsightly shine. They are also more prone to related facial skin conditions such as acne and seborrheic dermatitis. Controlling excessive sebum secretion and reducing oiliness is key to maintaining healthy skin.

[0004] Compared to traditional chemical oil-controlling substances, plant-based oil-controlling substances are safer and gentler, making them more popular with consumers and showing a trend of gradually replacing chemical oil-controlling substances. Currently, common plant-based oil-controlling ingredients include tea tree oil, hawthorn extract, and plant starch. However, due to the complexity of plant-based ingredients, related research is still in the development and exploration stage. Besides the efficacy of single plants, there is also great potential in selecting and combining multiple plant ingredients to better leverage their respective effects.

[0005] In summary, there is still a need in this field for oil-control products made from multiple plant-based ingredients that have excellent oil-control effects while also providing multiple benefits such as moisturizing, soothing, and repairing. Summary of the Invention

[0006] In order to solve the above problems, in a first aspect, the object of the present invention is to provide a composition comprising extracts from sea elm, extracts from sunflower seeds, extracts from edelweiss, and extracts from snow lotus.

[0007] In specific embodiments, the extract from *Eryngium stenoptera* in the composition of the present invention is *Eryngium stenoptera* extract or *Eryngium stenoptera* callus culture filtrate; the extract from *Edelweiss* is *Edelweiss* flower / leaf extract, *Edelweiss* extract, or *Edelweiss* callus extract; the extract from *Saussurea involucrata* is *Saussurea involucrata* extract or *Saussurea involucrata* cell culture; and / or the extract from sunflower seeds is sunflower seeds, sunflower seed oil, sunflower seed extract, or sunflower seed oil unsaponifiables.

[0008] In a specific embodiment, the composition of the present invention comprises the following components by weight: The extracts are 3-15 parts from sea elm, 8-12 parts from sunflower seeds, 1-5 parts from edelweiss, and 4-9 parts from snow lotus.

[0009] For example, the composition of the present invention comprises, by weight, 10 parts of the extract from *Eryngium spp.*, 9 parts of the extract from sunflower seeds, 1 part of the extract from *Edelweiss*, and 5 parts of the extract from *Saussurea involucrata*; 8 parts of the extract from *Eryngium spp.*, 11 parts of the extract from sunflower seeds, 2 parts of the extract from *Edelweiss*, and 6 parts of the extract from *Saussurea involucrata*; or 5 parts of the extract from *Eryngium spp.*, 8 parts of the extract from sunflower seeds, 4 parts of the extract from *Edelweiss*, and 8 parts of the extract from *Saussurea involucrata*.

[0010] In a preferred embodiment, the composition of the present invention comprises the following components by weight: The extract consists of 6-9 parts from sea elm, 10 parts from sunflower seed, 3 parts from edelweiss, and 6-8 parts from snow lotus.

[0011] In a more preferred embodiment, the composition of the present invention comprises, by weight, the following components: The extracts consist of 3 parts from sea elm, 10 parts from sunflower seeds, 3 parts from edelweiss, and 6 parts from snow lotus.

[0012] In specific embodiments, the compositions of the present invention further comprise caprylic / capric triglycerides and / or lecithin. In a preferred embodiment, the lecithin is soybean lecithin or hydrogenated lecithin.

[0013] In specific embodiments, the composition of the present invention may further comprise, by weight, 20-45 parts of the caprylic / capric triglyceride and / or 8-18 parts of the lecithin. In a preferred embodiment, the composition of the present invention may further comprise, by weight, 25-40 parts of the caprylic / capric triglyceride and / or 10-16 parts of the lecithin. In a more preferred embodiment, the composition of the present invention may further comprise, by weight, 30-35 parts of the caprylic / capric triglyceride and / or 12-14 parts of the lecithin.

[0014] In another specific embodiment, the composition of the present invention comprises 3 parts of the extract from sea elm, 10 parts of the extract from sunflower seeds, 3 parts of the extract from edelweiss, 6 parts of the extract from snow lotus, 20 parts of caprylic / capric triglycerides, and 8 parts of lecithin.

[0015] In a second aspect, the object of the present invention is to provide a method for preparing the composition as described in the first aspect, the method comprising dissolving lecithin in caprylic / capric triglycerides to obtain a mixture; dissolving the *Eryngium sambac* extract, the *Edelweiss* extract, and the *Saussurea involucrata* extract into the mixture respectively to obtain *Eryngium sambac* oil-soluble raw material, *Edelweiss* oil-soluble raw material, and *Saussurea involucrata* oil-soluble raw material; and adding the extract from sunflower seeds.

[0016] In a specific implementation, the preparation method of the present invention includes the following steps: (1) Measure out lecithin and dissolve it in caprylic / capric triglyceride to obtain the mixture; (2) Take the extracts from sea celery, the extracts from alpine edelweiss, and the extracts from snow lotus respectively, and dissolve them in the mixture prepared in (1) to obtain the sea celery oil-soluble raw material, the alpine edelweiss oil-soluble raw material and the snow lotus oil-soluble raw material; (3) Measure the oil-soluble raw materials of sea celery, edelweiss, and snow lotus in step (2) and mix them evenly to obtain the oil-soluble raw material mixture. Then, add the extract from sunflower seeds to the oil-soluble raw material mixture to obtain the composition.

[0017] In a preferred embodiment, the weight ratio of lecithin to caprylic / capric triglyceride in the preparation method of the present invention is 2:5. In a more preferred embodiment, the lecithin in the preparation method of the present invention is soybean lecithin or hydrogenated lecithin.

[0018] In a third aspect, the object of the present invention is to provide a cosmetic product comprising the composition as described in the first aspect.

[0019] In specific embodiments, the product of the present invention may further comprise emollients and fillers. In optional embodiments, the product of the present invention may further comprise colorants.

[0020] In specific implementations, the product of the present invention may be a cleaning product, a care product, or a beauty / decorative product.

[0021] For example, the products of this invention can be skin cleansing products such as facial cleanser and makeup remover; skin care products such as toner, lotion, cream, serum, and mask; or cosmetic products such as foundation, loose powder, setting powder, and sunscreen.

[0022] Beneficial effects: Compared with the prior art, the compositions of the present invention and cosmetic products using the same have the following advantages: (1) The oil-control composition provided by the present invention is based on the inventor’s research and exploration on the oil-control efficacy of sea celery. Four plant raw materials were selected: extract from sea celery, extract from sunflower seeds, extract from edelweiss, and extract from snow lotus. An oil-control composition with synergistic oil-control efficacy was obtained. The composition can also restore the skin’s normal function, improve the current situation of oily skin, and prevent the burden of other skin problems caused by oily skin.

[0023] (2) The composition of the present invention is oil-soluble and can also moisturize, soothe and repair the skin, especially for oily skin.

[0024] (3) The composition of the present invention can protect and enhance the skin barrier, resist oxidation, inhibit lipid synthesis, soothe, and improve oily and sensitive skin problems in multiple dimensions.

[0025] (4) The composition of the present invention is non-toxic, harmless and non-acne-causing, and will not cause additional burden on the skin.

[0026] (5) In addition to skincare cosmetics, the composition of the present invention can also be applied to various color cosmetics. Attached Figure Description

[0027] Figure 1 This is a fluorescence image from the oil control detection experiment of composition 1 of the present invention.

[0028] Figure 2 This is a fluorescence image of the soothing zebrafish test of composition 1 of the present invention.

[0029] Figure 3 This is the result of detecting the expression level of trypsin-like enzymes in composition 1 of the present invention.

[0030] Figure 4 This is a graph showing the results of testing the moisturizing effect of composition 1 of the present invention on zebrafish.

[0031] Figure 5 This is a fluorescence image from the oil control detection experiment of composition 2 of the present invention.

[0032] Figure 6 This is a fluorescence image from the oil control detection experiment of composition 3 of the present invention.

[0033] Figure 7 This is a fluorescence image from the oil control test of the control composition 1.

[0034] Figure 8 This is a fluorescence image from the oil control test of the control composition 2. Invention Details In this invention, the inventors unexpectedly discovered that combining the effective components from coastal eryngium, alpine edelweiss, snow lotus, and sunflower seeds can yield a composition with significant oil-controlling, moisturizing, and soothing effects.

[0036] definition Seaside iris ( Eryngium maritimum *Eryngium maritima*, also known as the sea gyrfalcon, is used as a herbal medicine to treat various diseases. Recent research on its chemical components has revealed that it possesses several secondary metabolites with unique structures and functions, leading to its application in the cosmetics field. Those skilled in the art should understand that "extract from *Eryngium maritima*" in this invention refers to substances containing effective components of *Eryngium maritima* obtained from *Eryngium maritima* (e.g., various organs, callus tissue, etc.), including but not limited to *Eryngium maritima* extract and *Eryngium maritima* callus culture filtrate already listed in the *Catalogue of Used Cosmetic Ingredients*, as well as raw materials containing effective components of *Eryngium maritima* that will be included in the *Catalogue of Used Cosmetic Ingredients* in the future. For example, the preparation method of *Eryngium maritima* callus culture filtrate is as follows: solid callus tissue is induced from *Eryngium maritima* explants; high-quality cells are screened and subjected to floating culture to obtain plant cell floating culture solution; and the solution is dried and pulverized to obtain the raw material.

[0037] Alpine Edelweiss ( Leontopodium alpinumThis material contains various substances with antioxidant, anti-inflammatory, and cell-protective effects, such as tannins, flavonoids, chlorogenic acid, and phytosterols, and has broad application prospects in the cosmetics field. Those skilled in the art should understand that "extracts from Edelweiss" in this invention refers to substances containing effective components of Edelweiss obtained from Edelweiss (e.g., various organs and callus tissues of Edelweiss), including but not limited to Edelweiss flower / leaf extract, Edelweiss extract, and Edelweiss callus tissue extract already listed in the "Catalogue of Used Cosmetic Ingredients," as well as raw materials containing effective components of Edelweiss that will be included in the "Catalogue of Used Cosmetic Ingredients" in the future. For example, the preparation method of Edelweiss callus extract is as follows: select Edelweiss explants to induce solid callus tissue, screen high-quality cells for virtual culture to obtain plant cell virtual culture solution, and dry and pulverize to obtain raw material.

[0038] Snow lotus ( Saussurea involucrata The entire plant can be used medicinally. Studies of its chemical composition have shown that it contains various active substances such as proteins, amino acids, flavonoids, and alkaloids, exhibiting multiple skincare benefits including antioxidant and whitening effects. Those skilled in the art should understand that "extracts from snow lotus" in this invention refers to substances containing effective components of snow lotus obtained from snow lotus (e.g., various organs, callus tissue, etc.), including but not limited to Tian Shan snow lotus cell cultures, snow lotus extracts already listed in the "Catalogue of Used Cosmetic Ingredients," and raw materials containing effective components of snow lotus that will be included in the "Catalogue of Used Cosmetic Ingredients" in the future. For example, the preparation method of snow lotus extract is as follows: solid callus tissue is induced from snow lotus explants; high-quality cells are screened and subjected to floating culture to obtain plant cell floating culture solution; and the solution is dried and pulverized to obtain the raw material.

[0039] Sunflower (Helianthus annuus L.), its seeds, namely sunflower seeds, contain a variety of antioxidant, whitening, and anti-aging active substances, such as zinc, vitamin E, and phenolic acids. Those skilled in the art should understand that "extracts from sunflower seeds" in this invention refers to substances containing effective components of sunflower seeds obtained from sunflower seeds as raw materials, including but not limited to sunflower seed (HELIANTHUS ANNUUS (SUNFLOWER) SEED), sunflower seed oil (HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL), sunflower seed extract (HELIANTHUS ANNUUS (SUNFLOWER) SEED EXTRACT), and sunflower seed oil unsaponifiables (HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL UNSAPONIFIABLES) already listed in the "Catalogue of Used Cosmetic Ingredients," as well as raw materials containing effective components of sunflower seeds that will be included in the "Catalogue of Used Cosmetic Ingredients" in the future. Detailed Implementation

[0040] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are some embodiments of the present invention, but not all embodiments.

[0041] Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0042] The technical solution of the present invention will be further described below with reference to the accompanying drawings and specific embodiments.

[0043] Example 1: Preparation and efficacy testing of composition 1 of the present invention Preparation of the composition 1 of the present invention (1) Take 30g of Edelweiss callus extract (supplier: NAOLYS), 30g of Tian Shan Snow Lotus cell culture (supplier: Dalian Purikang Biotechnology Co., Ltd.), and 30g of Erycibe callus culture filtrate (supplier: Ansaibo (Chongqing) Biotechnology Co., Ltd.); (2) Measure 20g of soybean lecithin and dissolve it in 50g of caprylic / capric triglyceride to prepare 3 mixtures; (3) Dissolve the coastal celery callus culture filtrate, alpine edelweiss callus extract, and Tian Shan snow lotus cell culture measured in step (1) into the three mixtures prepared in (2) to fully dissolve each raw material and obtain the coastal celery oil-soluble raw material, the alpine edelweiss oil-soluble raw material and the snow lotus oil-soluble raw material respectively. (4) Take 20g of sea celery oil-soluble raw material, 20g of alpine edelweiss oil-soluble raw material and 40g of snow lotus oil-soluble raw material from step (3), mix them evenly to obtain an oil-soluble raw material mixture, and then add 20g of sunflower seed oil to the oil-soluble raw material mixture to obtain the composition.

[0044] The extracts used in the other embodiments and comparative examples below are the same as those used in this embodiment.

[0045] The proportions of each raw material in the oil-controlling composition provided in this embodiment are shown in the table below:

[0046] Oil control efficacy test The principle of the oil-control detection method: Sebaceous glands are the source and target tissue of androgens. Dehydroepiandrosterone (DHEA) is produced in sebaceous glands, which, through a series of enzymatic catalysis, is converted into the most active testosterone and 5α-dihydrotestosterone (5α-DHT). These stimulate lipid synthesis and the proliferation and differentiation of sebaceous gland cells. During this proliferation and differentiation process, undifferentiated immature cells proliferate first, and some daughter cells form lipid droplets, which migrate towards the center of the gland cell, gradually developing and differentiating into mature sebaceous gland cells capable of storing and secreting lipids. This detection method sets up a model control group (the culture medium contains testosterone to stimulate sebaceous gland cell proliferation and sebum secretion) and a sample group (the culture medium contains testosterone and different concentrations of the composition of this invention). The amount of sebum secreted by sebaceous gland cells in each group is detected by Nile Red staining to determine whether the sample has an oil-control effect.

[0047] Experimental steps: (1) Sebaceous gland cells were seeded in six-well plates (3×10⁻⁶ cells / wells). 5 Sebaceous gland cell culture medium (purchased from Guangdong Boxi Biotechnology Co., Ltd.) was incubated at 37 °C, 5% CO2 for 24 hours.

[0048] (2) After incubation, the model control group was replaced with a culture medium containing testosterone (i.e., 100 mM testosterone was added to the sebaceous gland cell culture medium), and the sample group was replaced with a culture medium containing the corresponding concentration of sample and testosterone (i.e., the corresponding concentration of sample and 100 mM testosterone were added to the sebaceous gland cell culture medium). The incubation was carried out at 37 °C and 5% CO2 for 24 hours.

[0049] (3) After incubation, remove the culture medium, pre-cool and wash three times with D-Manks, fix with 60% isopropanol, wash with D-Manks, stain with Nile Red, take pictures with a fluorescence microscope, analyze the fluorescence intensity of each group using ImageJ software and calculate using the following formula: Where A represents fluorescence intensity.

[0050] (3) Sample preparation method: First, weigh a certain amount of the composition sample and dilute it with DMSO (dimethyl sulfoxide) to a stock solution with a concentration of 20%. Then, take a certain amount of the stock solution and dilute it with cell culture medium to the required concentration.

[0051] The test results are shown in the table below:

[0052] Soothing Zebrafish Test Principle: Sodium dodecyl sulfate (SLS) may trigger a stimulating response in the body. When this stimulant enters the zebrafish, it induces an inflammatory response, causing neutrophils to initiate an immune response, migrate to the skin epidermis, and aggregate. The change in the number of neutrophils in the skin before and after treatment with a transgenic green fluorescent neutrophil strain of zebrafish (MPX) was used to detect the soothing efficacy of the sample. Neutrophils in zebrafish embryos are highly similar to human neutrophils in morphology, biochemistry, and physiological function. Neutrophils are the first white blood cells to appear at sites of injury or pathogen invasion, acting to clear infection or harmful substances. A model of neutrophil aggregation induced by copper sulfate damage in the lateral line region of zebrafish embryos was used for testing. The change in the number of neutrophils in the lateral line region of the embryos in the test substance treatment group and the model control group was compared, and the neutrophil inhibition rate was calculated to evaluate the soothing efficacy of the raw material, formulation, or product.

[0053] Experimental system: transgenic neutrophil-containing green fluorescent zebrafish (MPX).

[0054] Zebrafish age: 2 days post-fertilization (2 dpf).

[0055] Sample size per group: 15 tails (N=10).

[0056] Adult fish rearing and breeding methods: The adult fish rearing and breeding methods meet the requirements of international AAALAC certification (certification number: 001458).

[0057] Experimental steps: 1. Randomly select zebrafish into a 6-well plate, with 15 fish per well.

[0058] 2. A zebrafish skin inflammation model was established by water-soluble administration of SLS.

[0059] 3. The sample was administered in water, and a normal control group and a model control group were set up. The volume of each well was 3 mL.

[0060] 4. Incubate at 28 ℃ in the dark for 18 h.

[0061] 5. Ten zebrafish were randomly selected from each experimental group and photographed under a fluorescence microscope (see appendix for some results). Figure 2 Data was analyzed and collected using advanced image processing software. The number of neutrophils (N) in zebrafish skin was analyzed, and the soothing efficacy of the sample was calculated using the formula below to determine whether it possessed a soothing effect. Calculation of soothing efficacy:

[0062] The test results are as follows:

[0063] The test results showed that the number of neutrophils in the zebrafish of the sample group was significantly reduced compared with that of the model control group, indicating that the sample has significant anti-inflammatory and soothing effects.

[0064] Detection of trypsin expression levels Principle: Tryptase is a neutral protease pre-synthesized within mast cells and is an important indicator for clinically testing allergic reactions. When zebrafish experience an allergic reaction, mast cells are also induced to secrete tryptase, which complexes with BAPNA substrates, exhibiting a maximum absorption peak at 405 nm. The relative absorbance (OD405 value) of the whole zebrafish tryptase expression level is detected using a microplate reader to evaluate the soothing efficacy of the sample.

[0065] Experimental system: Wild-type AB strain.

[0066] Zebrafish age: 2 days post-fertilization (2 dpf).

[0067] Sample size per group: 10 tails (three biological replicates, N=3).

[0068] Adult fish rearing and breeding methods: meet the requirements of international AAALAC certification (certification number: 001458).

[0069] Experimental steps: 1. Randomly select zebrafish into a 12-well plate, with 10 fish per well.

[0070] 2. A zebrafish allergy model was established by administering 2,4-dinitrochlorobenzene (DNCB) in water.

[0071] 3. The sample was administered in water, with a normal control group and a model control group included. Each well contained 1 mL. Three biological replicates were performed.

[0072] 4. Each experimental group and BAPNA were incubated together at 28 ℃ in the dark for 24 h.

[0073] 5. Use an ELISA reader to detect the OD value (trypsin content) of zebrafish in each experimental group at 405 nm, calculate the trypsin expression level (T) of zebrafish, and calculate and determine whether the sample has a soothing effect according to the formula below.

[0074]

[0075] Test results (see) Figure 3 The results showed that the expression level of trypsin in the sample group was significantly lower than that in the model control group, indicating that the sample has significant anti-allergic and soothing effects.

[0076] Zebrafish Moisturizing Efficacy Test Principle: Zebrafish treated with sodium chloride will lose water and shrink due to osmotic pressure, and the tail area will become smaller due to shrinkage. The effect of the tail area is used to evaluate the moisturizing effect of cosmetics.

[0077] Experimental system: melanin allele mutant zebrafish (Albino).

[0078] Zebrafish age: 2 days post-fertilization (2 dpf).

[0079] Sample size per group: 15 tails (N=10).

[0080] Adult fish rearing and breeding methods: meet the requirements of international AAALAC certification (certification number: 001458).

[0081] Experimental steps: 1. Randomly select zebrafish into a 6-well plate, with 15 fish per well.

[0082] 2. The sample was administered in water, and a normal control group and a model control group were set up. The volume of each well was 3 mL.

[0083] 3. Simultaneously, sodium chloride was administered in water to establish a zebrafish skin dehydration model.

[0084] 4. Incubate at 28 ℃ in the dark for 22 h.

[0085] 5. Ten zebrafish were randomly selected from each experimental group and photographed under a dissecting microscope (some results can be found in [reference needed]). Figure 4The data was analyzed and collected using advanced image processing software. The area (S) of the zebrafish tail was analyzed, and the moisturizing effect of the sample was calculated according to the formula below to determine whether it has a moisturizing effect.

[0086]

[0087] The test results are as follows:

[0088] The test results showed that the tail area of ​​the sample group was significantly increased compared with that of the model control group, indicating that the sample has a significant moisturizing effect.

[0089] Example 2: Preparation of Composition 2 of the Present Invention and Testing of its Oil-Control Efficacy Preparation of the composition 2 of the present invention (1) Measure 30g of coastal celery callus culture filtrate, 30g of alpine edelweiss callus extract, and 30g of Tian Shan snow lotus cell culture. (2) Measure 20g of soybean lecithin and dissolve it in 50g of caprylic / capric triglyceride to prepare 3 mixtures; (3) Dissolve the coastal celery callus culture filtrate, alpine edelweiss callus extract, and Tian Shan snow lotus cell culture measured in step (1) into the three mixtures prepared in (2) to fully dissolve each raw material and obtain the coastal celery oil-soluble raw material, the alpine edelweiss oil-soluble raw material and the snow lotus oil-soluble raw material respectively. (4) Take 50g of sea celery oil-soluble raw material, 10g of alpine edelweiss oil-soluble raw material and 30g of snow lotus oil-soluble raw material from step (3), mix them evenly to obtain an oil-soluble raw material mixture, and then add 20g of sunflower seed oil to the oil-soluble raw material mixture to obtain the composition.

[0090] The proportions of each raw material in the oil-controlling composition provided in this embodiment are shown in the table below:

[0091] Oil control efficacy test The oil control test method is the same as in Example 1. The test results are shown in the table below:

[0092] Example 3: Preparation of Composition 3 of the Present Invention and Testing of its Oil-Control Efficacy Preparation of the composition of the present invention 3 (1) Measure 30g of coastal celery callus culture filtrate, 30g of alpine edelweiss callus extract, and 30g of Tian Shan snow lotus cell culture. (2) Measure 20g of soybean lecithin and dissolve it in 50g of caprylic / capric triglyceride to prepare 3 mixtures; (3) Dissolve the coastal celery callus culture filtrate, alpine edelweiss callus extract, and Tian Shan snow lotus cell culture measured in step (1) into the three mixtures prepared in (2) to fully dissolve each raw material and obtain the coastal celery oil-soluble raw material, the alpine edelweiss oil-soluble raw material and the snow lotus oil-soluble raw material respectively. (4) Take 50g of sea celery oil-soluble raw material, 10g of alpine edelweiss oil-soluble raw material and 30g of snow lotus oil-soluble raw material from step (3), mix them evenly to obtain an oil-soluble raw material mixture, and then add 20g of sunflower seed oil to the oil-soluble raw material mixture to obtain the composition.

[0093] The proportions of each raw material in the oil-controlling composition provided in this embodiment are shown in the table below:

[0094] Oil control efficacy test The oil control test method is the same as in Example 1. The test results are shown in the table below:

[0095] Comparative Example 1: Preparation of Comparative Composition 1 and Testing of its Oil-Control Efficacy Preparation of comparative composition 1 (1) Take 6g of the filtrate from the callus culture of *Eryngium sibiricum*. (2) Measure 4g of soybean lecithin and dissolve it in 90g of caprylic / capric triglyceride; (3) Dissolve the filtrate of callus culture of sea celery measured in step (1) in the mixture prepared in step (2) to fully dissolve each raw material and obtain comparative composition 1.

[0096] The proportions of each ingredient in comparative composition 1 provided in this comparative example are shown in the table below:

[0097] Oil control efficacy test The oil control test method is the same as in Example 1. The test results are shown in the table below:

[0098] Comparative Example 2: Preparation of Comparative Composition 2 and Testing of its Oil-Control Efficacy Preparation of comparative composition 2 (1) Measure 30g of Edelweiss callus extract and 30g of Tian Shan snow lotus cell culture; (2) Measure 20g of soybean lecithin and dissolve it in 50g of caprylic / capric triglyceride to prepare two mixtures; (3) Dissolve the extract of Edelweiss callus tissue and the cell culture of Saussurea in the Tianshan Mountains measured in step (1) into the three parts of the mixture prepared in (2) to fully dissolve each raw material and obtain the oil-soluble raw material of Edelweiss and the oil-soluble raw material of Saussurea in the Tianshan Mountains respectively. (4) Take 20g of Edelweiss oil-soluble raw material and 40g of Snow Lotus oil-soluble raw material from step (3), mix them evenly to obtain an oil-soluble raw material mixture, dissolve the oil-soluble raw material mixture in 20g of sunflower seed oil and then dissolve it in 20g of caprylic / capric triglyceride oil to obtain the comparative composition 2.

[0099] The proportions of each ingredient in comparative composition 2 provided in this comparative example are shown in the table below:

[0100] Oil control efficacy test The oil control test method is the same as in Example 1. The test results are shown in the table below:

[0101] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of the invention. Various changes and modifications can be made to the invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the present invention as claimed. The scope of protection of the present invention is defined by the appended claims and their equivalents.

Claims

1. A composition, characterized in that, The composition comprises extracts from sea fennel, sunflower seeds, edelweiss, and snow lotus; 3-15 parts of the sea fennel extract, 8-12 parts of the sunflower seed extract, 1-5 parts of the edelweiss extract, and 4-9 parts of the snow lotus extract.

2. The composition according to claim 1, characterized in that, The extract from *Eryngium spp.* is *Eryngium spp.* extract or *Eryngium spp.* callus culture filtrate; the extract from *Edelweiss oleander* is *Edelweiss oleander* flower / leaf extract, *Edelweiss oleander* extract or *Edelweiss oleander* callus extract; the extract from *Saussurea involucrata* is *Saussurea involucrata* extract or *Saussurea involucrata* cell culture; and / or the extract from sunflower seeds is sunflower seeds, sunflower seed oil, sunflower seed extract or sunflower seed oil unsaponifiables.

3. The composition according to claim 1 or 2, characterized in that, The composition comprises, by weight, the following components: The extract comprises 6-9 parts of sea elm extract, 10 parts of sunflower seed extract, 3 parts of alpine edelweiss extract, and 6-8 parts of snow lotus extract; preferably, it comprises 3 parts of sea elm extract, 10 parts of sunflower seed extract, 3 parts of alpine edelweiss extract, and 6 parts of snow lotus extract.

4. The composition according to any one of claims 1-3, characterized in that, The composition further comprises caprylic / capric triglycerides and / or lecithin, such as soybean lecithin or hydrogenated lecithin; preferably, the composition further comprises 20-45 parts by weight of caprylic / capric triglycerides and / or 8-18 parts by weight of lecithin; more preferably, the composition further comprises 25-40 parts by weight of caprylic / capric triglycerides and / or 10-16 parts by weight of lecithin; most preferably, the composition further comprises 30-35 parts by weight of caprylic / capric triglycerides and / or 12-14 parts by weight of lecithin.

5. The composition according to claim 4, characterized in that, The composition comprises 3 parts of the extract from sea elm, 10 parts of the extract from sunflower seeds, 3 parts of the extract from edelweiss, 6 parts of the extract from snow lotus, 20 parts of caprylic / capric triglycerides, and 8 parts of lecithin.

6. The method for preparing the composition according to any one of claims 1-5, characterized in that, The method includes dissolving lecithin in caprylic / capric triglycerides to obtain a mixture; dissolving the extracts from *Eryngium sibiricum*, *Edelweiss*, and *Saussurea involucrata* into the mixture to obtain *Eryngium sibiricum* oil-soluble raw materials, *Edelweiss* oil-soluble raw materials, and *Saussurea involucrata* oil-soluble raw materials; and adding the extract from sunflower seeds.

7. The preparation method according to claim 6, characterized in that, The method includes the following steps: (1) Measure out lecithin and dissolve it in caprylic / capric triglyceride to obtain the mixture; (2) The extracts from *Eryngium sibiricum*, *Edelweiss*, and *Saussurea involucrata* are measured separately and dissolved in the mixture prepared in (1) to obtain the oil-soluble raw materials from *Eryngium sibiricum*, *Edelweiss*, and *Saussurea involucrata*; and (3) Measure the oil-soluble raw materials of sea celery, edelweiss, and snow lotus in step (2) and mix them evenly to obtain the oil-soluble raw material mixture. Then add the extract from sunflower seeds to the oil-soluble raw material mixture to obtain the composition. Preferably, the weight ratio of lecithin to caprylic / capric triglycerides is 2:5; more preferably, the lecithin is soybean lecithin or hydrogenated lecithin.

8. A cosmetic product, characterized in that, The product therein contains the composition as described in any one of claims 1-5.

9. The product as described in claim 7, characterized in that, The product also contains emollients, antioxidants, surfactants, fragrances, preservatives or sunscreens, and optionally colorants.

10. The product as described in claim 8 or 9, characterized in that, The products mentioned are cleaning products, care products, or beauty / makeup products.

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