A sugar detection system and method

CN122084786APending Publication Date: 2026-05-26QINGDAO SHENGHAN CHROMATOGRAPH TECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
QINGDAO SHENGHAN CHROMATOGRAPH TECH CO LTD
Filing Date
2026-02-13
Publication Date
2026-05-26

AI Technical Summary

Technical Problem

Existing technologies achieve high separation of carbohydrates in low-concentration eluents, but the detection device has low responsiveness, resulting in high limits of detection and quantification. This makes it difficult to reliably detect or quantify trace or ultra-trace carbohydrate components, and baseline drift affects detection stability.

Method used

The system employs a chromatographic column, a detection device, and an eluent concentration adjustment device. The eluent concentration is controlled by adjusting the flow path and the electrolysis chamber, and the sodium hydroxide concentration is adjusted by gradient current to ensure that the eluent reaches the optimal response conditions in the detection device.

Benefits of technology

It achieves improved detection sensitivity while ensuring separation, eliminates baseline drift, improves chromatogram quality and the level of automation in detection, and improves the signal-to-noise ratio for identifying low-content components.

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Abstract

This invention provides a carbohydrate detection system and method. The system includes a chromatographic column, a detection device, and an eluent concentration adjustment device disposed between the chromatographic column and the detection device. The chromatographic column is connected to an inlet unit, which provides sodium hydroxide eluents of different concentrations. The chromatographic column performs chromatographic separation of a sample solution based on the sodium hydroxide eluent. The eluent concentration adjustment device receives the separated sample solution from the chromatographic column, adjusts the sodium hydroxide concentration of the separated sample solution to a preset target concentration, and delivers it to the detection device. The detection device is used to determine the carbohydrates in the separated sample solution. This invention solves the problem in the prior art where the separation of carbohydrates under low-concentration eluents contradicts the response under high-concentration eluents in the detection device. It ensures reliable chromatographic separation while compensating for the concentration of the eluent after separation, improving response sensitivity and optimizing detection results.
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