A Tibetan medicine compound composition, a hair loss prevention and hair strengthening shampoo and its preparation method

Abstract

This invention belongs to the field of daily cosmetics technology, specifically relating to a Tibetan medicine compound composition, an anti-hair loss and hair-strengthening shampoo, and its preparation method. By weight, the raw materials of the Tibetan medicine compound composition include: 0.7-9 parts ginseng, 0.7-9 parts tremella, 7-20 parts he shou wu, 7-25 parts arborvitae leaves, 0.7-9 parts ginger, 0.7-9 parts wolfberry root, 0.7-9 parts eclipta prostrata, and 0.7-9 parts black sesame. Through specific formulation and preparation processes, this invention achieves synergistic effects among the components, forming a triple mechanism of "antioxidant – promoting microcirculation – regulating hair follicle cycle," providing a multi-target solution for preventing hair loss and strengthening hair.

Description

Technical Field

[0001] This invention belongs to the field of daily cosmetics technology, specifically relating to a Tibetan medicine compound composition, an anti-hair loss and hair-strengthening shampoo, and its preparation method. Background Technology

[0002] Most commercially available hair care products currently rely on sulfate surfactants, silicone oils, and other chemical ingredients. While these can improve hair smoothness in the short term, long-term use can damage the scalp barrier function, leading to problems such as hair follicle atrophy and scalp sensitivity. In the field of hair loss prevention and anti-aging, Western medicines such as minoxidil and finasteride have some efficacy, but they may be accompanied by side effects such as scalp irritation and hormonal imbalances, and relapse is common after discontinuation, failing to meet consumers' needs for safe and long-lasting solutions.

[0003] Tibetan medicine also has a unique understanding of hair health. The Four Medical Classics record that an imbalance of "dragon" can lead to hair loss, and advocates restoring hair function by harmonizing the three factors (dragon, tribulation, and peghnath). However, traditional Tibetan hair care formulas are mostly used in the form of decoctions or powders, which have problems such as low extraction efficiency of effective ingredients and poor compatibility with external dosage forms. Moreover, the proportions of the six herbal combinations rely heavily on experience and lack scientific optimization based on quantitative analysis of active ingredients.

[0004] Chinese invention patent application CN113576988A discloses an anti-hair loss and hair-strengthening shampoo and its manufacturing method, comprising the following components: ammonium lauryl ether sulfate, ammonium lauryl sulfate, sodium lauroamphoacetate, arborvitae leaf extract, Polygonum multiflorum root extract, ginger root extract, polydimethylsiloxane, sodium dodecylbenzene sulfonate, cocamide MEA, sodium lauroyl sarcosinate, sodium PCA, fragrance, DMDM ​​hydantoin, guar gum hydroxypropyltrimethylammonium chloride, pyridoxine HCl, sodium chloride, allantoin, hydroxypropyl methylcellulose, citric acid, disodium EDTA, and deionized water. This invention, by adding Polygonum multiflorum extract, ginger root extract, and arborvitae leaf extract, can effectively cleanse the scalp, promote melanin production in hair, prevent hair loss, and nourish hair follicles. However, the surfactants in this invention's formula are relatively highly irritating, and long-term use may place a burden on the scalp; its suitability for gentle hair care needs improvement.

[0005] Chinese invention patent application CN106606458A discloses an anti-hair loss and hair-strengthening nourishing shampoo, comprising the following parts by weight: 40-60 parts sodium lauryl polyoxyethylene ether sulfate, 20-40 parts coconut oil diethanolamide, 30-50 parts small-particle-size emulsified silicone oil, 1-35 parts Usma grass, 5-20 parts black cumin seeds, 5-60 parts Polygonum multiflorum, 5-60 parts ginger, 1-20 parts Chamaggu, and 2000-3000 parts deionized water. This invention uses pure natural plant extracts, which can effectively promote hair growth and strengthen hair, prevent hair loss, stimulate scalp blood circulation, activate hair follicles, and nourish the scalp. However, the invention contains a relatively high content of some oily components, and long-term use may increase the risk of clogged pores. There is still room for improvement in the gentle conditioning effect on the scalp and the product's user experience.

[0006] In summary, existing hair loss prevention and hair care technologies have significant shortcomings in terms of ingredient safety, long-lasting effects, dosage form compatibility, and scientific formulation. There is an urgent need to develop a safe and long-lasting hair loss prevention and hair strengthening solution based on natural Tibetan medicine compound, possessing a multi-target synergistic mechanism, and compatible with topical shampoo and conditioner formulations. Summary of the Invention

[0007] To address the shortcomings of existing technologies, this invention provides a Tibetan medicine compound composition, an anti-hair loss and hair-strengthening shampoo, and a method for preparing the same.

[0008] To achieve the above-mentioned objectives of this invention, the specific technical solution adopted by this invention is as follows:

[0009] A Tibetan medicine compound composition, by weight, comprises the following raw materials: ginseng 0.7-9 parts, tremella fuciformis 0.7-9 parts, Polygonum multiflorum 7-20 parts, Platycladus orientalis leaf 7-25 parts, ginger 0.7-9 parts, wolfberry root 0.7-9 parts, Eclipta prostrata 0.7-9 parts, and black sesame 0.7-9 parts.

[0010] Preferably, the preparation method of the Tibetan medicine compound composition includes: S1. Grind ginseng, white fungus, fleeceflower root, arborvitae leaves, ginger, wolfberry root, eclipta prostrata and black sesame seeds into powder, mix them, add water and decoct, filter, concentrate to obtain concentrated liquid; S2. Add ethanol to the concentrate, precipitate the alcohol, let it stand, recover the ethanol, concentrate, and the product is obtained.

[0011] Preferably, in step S1, the amount of water added is 5-20 times the total mass of ginseng, tremella, he shou wu, arborvitae leaves, ginger, wolfberry root, eclipta prostrata and black sesame, the decoction temperature is 85-95℃, the decoction time is 1.5-2.5h, the decoction is performed 1-2 times, and the relative density is 1.10-1.15 when concentrated to 25℃.

[0012] Preferably, in step S2, ethanol is added to a volume concentration of 65%-85%, the standing temperature is 2-6°C, the standing time is 10-30 hours, and the concentration is continued until no alcohol odor is detected.

[0013] This invention also relates to the application of the above-mentioned Tibetan medicine compound composition in the preparation of anti-hair loss and hair-strengthening shampoo.

[0014] This invention also provides an anti-hair loss and hair-strengthening shampoo, the raw materials of which include: water, moisturizer, conditioning agent, surfactant, stabilizer, chelating agent, pH adjuster, preservative, filler, and the above-mentioned Tibetan medicine compound composition. Preferably, by mass percentage, the raw materials of the anti-hair loss and hair-strengthening shampoo include: 1-3% moisturizer, 5-10% conditioning agent, 20-40% surfactant, 0.1-0.5% stabilizer, 0.3-0.8% chelating agent, 0.1-0.4% pH adjuster, 0.2-0.8% preservative, 0.1-0.3% filler, 1-10% Tibetan medicine compound composition, and the balance being water.

[0015] Preferably, the humectant is the humectant MOISOFT AM, the stabilizer is an acrylate / C10-30 alkanol acrylate crosspolymer, the chelating agent is hydroxyethyl diphosphate, the pH adjuster is citric acid, the preservative is phenoxyethanol, and the filler is titanium dioxide.

[0016] Preferably, the surfactant includes sodium lauryl ether sulfate, sodium dodecyl sulfate, cocamidopropyl betaine, amino acid surfactant, guar hydroxypropyltrimethylammonium chloride, and palm kernel oleamide DEA.

[0017] Preferably, the conditioning agent comprises adenosine, capryloyl glycine, cocamide MEA, behenamidopropyl dimethylamine, polydimethylsiloxane, hydroxypropyl methylcellulose, quaternary ammonium salt-82, PEG-8 diisostearate, an anionic emulsion of polydimethylsiloxane, a natural active complex polypeptide hair conditioning agent, and hydrolyzed wheat protein PG-propylsilanetriol; the anionic emulsion of polydimethylsiloxane is designated DOWSIL. TM 1785 POE Emulsion, the model number of the natural active complex polypeptide hair conditioner is ZS-PE-27B.

[0018] Compared with the prior art, the present invention has the following beneficial effects: (1) The Tibetan medicine compound composition provided by the present invention, through a specific weight ratio of eight medicinal materials including ginseng, tremella, he shou wu, arborvitae leaf, ginger, wolfberry root, eclipta prostrata and black sesame, combined with a preparation process of water extraction followed by alcohol precipitation, maximizes the extraction and purification of active ingredients such as saponins, flavonoids and polysaccharides. The components work synergistically to form a triple mechanism of "antioxidant-promoting microcirculation-regulating hair follicle cycle", providing a multi-target solution for preventing hair loss and strengthening hair.

[0019] (2) The surfactant and conditioning agent system of the present invention reduces the combing force of the shampoo by more than 26% and increases the hair breaking force by more than 25%, achieving the integrated effect of "cleaning-anti-hair loss-nourishing-repair". Detailed Implementation

[0020] The present invention will be further described in detail below with reference to specific embodiments. The following embodiments are not intended to limit the present invention, but only to illustrate the present invention. Unless otherwise specified, the experimental methods used in the following embodiments are generally performed under conventional conditions. Unless otherwise specified, the materials and reagents used in the following embodiments are commercially available.

[0021] Information on the sources of raw materials is shown in Table 1.

[0022] Table 1 Raw Material Source Information

[0023] Example 1 A Tibetan medicine compound composition, by weight, consists of the following ingredients: 1 part ginseng, 1 part white fungus, 10 parts Polygonum multiflorum, 15 parts Platycladus orientalis leaves, 1 part ginger, 1 part wolfberry root, 3 parts Eclipta prostrata, and 3 parts black sesame.

[0024] The preparation method is as follows: After crushing the above raw materials, pass them through a 10-mesh sieve, add 20 times the amount of water, decoct at 95°C for 2 hours (once), filter, concentrate the filtrate to a relative density of 1.10 at 25°C, add ethanol to make the alcohol content reach 70%, let stand at 4°C for 24 hours, take the supernatant, recover the ethanol and concentrate until there is no alcohol taste, and the compound medicinal material extract is obtained.

[0025] A hair loss prevention and hair strengthening shampoo is prepared according to the formula shown in Table 2.

[0026] Table 2 Raw Materials and Usage

[0027] The preparation method of the above-mentioned anti-hair loss and hair strengthening shampoo: (1) Mix the raw materials in phase A, heat to 80°C and stir evenly to obtain mixture a.

[0028] (2) When the mixture a is cooled to 55°C, phase B is added, homogenized at 50 rpm for 10 minutes, and kept warm for 10 minutes to defoam, to obtain mixture b.

[0029] (3) When mixture b is cooled to 45°C, add phase C and Tibetan medicine compound composition, stir evenly, and the mixture is obtained.

[0030] Example 2 A Tibetan medicine compound composition, by weight, consists of the following ingredients: 0.7 parts ginseng, 9 parts tremella, 20 parts he shou wu, 15 parts arborvitae leaves, 5 parts ginger, 5 parts wolfberry root, 0.7 parts eclipta prostrata, and 9 parts black sesame.

[0031] The preparation method is as follows: After crushing the above raw materials, pass them through a 10-mesh sieve, add 15 times the amount of water, decoct at 90°C for 2 hours (once), filter, concentrate the filtrate to a relative density of 1.10 at 25°C, add ethanol to make the alcohol content reach 70%, let stand at 4°C for 24 hours, take the supernatant, recover the ethanol and concentrate until there is no alcohol taste, and the compound medicinal material extract is obtained.

[0032] A hair loss prevention and hair strengthening shampoo is prepared according to the formula shown in Table 3.

[0033] Table 3 Raw Materials and Usage

[0034] The preparation method of the above-mentioned anti-hair loss and hair strengthening shampoo is the same as that in Example 1.

[0035] Example 3 A Tibetan medicine compound composition, by weight, consists of the following ingredients: 9 parts ginseng, 0.7 parts white fungus, 7 parts Polygonum multiflorum, 20 parts Platycladus orientalis leaves, 9 parts ginger, 3 parts wolfberry root, 9 parts Eclipta prostrata, and 0.7 parts black sesame.

[0036] The preparation method is as follows: After crushing the above raw materials, pass them through a 10-mesh sieve, add 10 times the amount of water, decoct at 85°C for 2 hours (once), filter, concentrate the filtrate to a relative density of 1.10 at 25°C, add ethanol to make the alcohol content reach 70%, let stand at 4°C for 24 hours, take the supernatant, recover the ethanol and concentrate until there is no alcohol taste, and the compound medicinal material extract is obtained.

[0037] A hair loss prevention and hair strengthening shampoo is prepared according to the formula shown in Table 4.

[0038] Table 4 Raw Materials and Usage

[0039] The preparation method of the above-mentioned anti-hair loss and hair strengthening shampoo is the same as that in Example 1.

[0040] Comparative Example 1 The only difference between this comparative example and Example 1 is the ratio of raw materials in the compound Tibetan medicinal extract. Specifically, it consists of: 0.5 parts ginseng, 1 part tremella, 5 parts he shou wu, 10 parts arborvitae leaves, 10 parts ginger, 2.5 parts wolfberry root, 5.5 parts eclipta prostrata, and 0.5 parts black sesame. The preparation method is the same as in Example 1.

[0041] A hair loss prevention and hair strengthening shampoo, the raw material composition and preparation method of which are completely consistent with those of Example 1.

[0042] Comparative Example 2 The only difference between this comparative example and Example 1 is the preparation method of the compound Tibetan medicine extract, which is different: Ginseng, white fungus, Polygonum multiflorum, Platycladus orientalis leaves, ginger, wolfberry root, Eclipta prostrata and black sesame are mixed, pulverized and passed through a 10-mesh sieve. 20 times the amount of water is added and decocted at 95℃ for 2 hours (once). After filtration, the filtrate is concentrated to a relative density of 1.10 at 25℃ to obtain the compound medicinal extract.

[0043] A hair loss prevention and hair strengthening shampoo, the raw material composition and preparation method of which are completely consistent with those of Example 1.

[0044] Comparative Example 3 The only difference between this comparative example and Example 1 is the composition of the compound Tibetan medicinal extract: 1 part ginseng, 1 part tremella, 10 parts he shou wu, 15 parts arborvitae leaves, 1 part ginger, 4 parts wolfberry root, and 3 parts eclipta prostrata. The preparation method is the same as in Example 1.

[0045] A hair loss prevention and hair strengthening shampoo, the raw material composition and preparation method of which are completely consistent with those of Example 1.

[0046] Comparative Example 4 The only difference between this comparative example and Example 1 is the composition of the compound Tibetan medicinal extract: 1 part ginseng, 1 part tremella, 10 parts he shou wu, 15 parts arborvitae leaves, 1 part ginger, 3 parts eclipta prostrata, and 4 parts black sesame. The preparation method is the same as in Example 1.

[0047] A hair loss prevention and hair strengthening shampoo, the raw material composition and preparation method of which are completely consistent with those of Example 1.

[0048] Comparative Example 5 The only difference between this comparative example and the shampoo in Example 1 is the amount of natural active complex polypeptide hair conditioner (ZS-PE-27B) and hydrolyzed wheat protein PG-propylsilanetriol (W5-PG). Specifically: The hair conditioner does not contain any natural active complex polypeptide hair conditioner (ZS-PE-27B), and the amount of hydrolyzed wheat protein PG-propylsilanetriol (W5-PG) is 1.5wt.

[0049] Comparative Example 6 The only difference between this comparative example and the shampoo in Example 1 is the amount of natural active complex polypeptide hair conditioner (ZS-PE-27B) and hydrolyzed wheat protein PG-propylsilanetriol (W5-PG). Specifically: The amount of natural active complex polypeptide hair conditioner (ZS-PE-27B) is 1.5wt, without the addition of hydrolyzed wheat protein PG-propylsilanetriol (W5-PG).

[0050] Comparative Example 7 The only difference between this comparative example and Example 1 is that the shampoo ingredients include: anionic emulsion of polydimethylsiloxane (DOWSIL). TM Replace 1785 POE Emulsion with an equal amount of hydrolyzed wheat protein PG-propylsilanetriol (W5-PG).

[0051] Effect test Test Example 1: Human Safety Evaluation 1. Experimental Materials Test substance: The anti-hair loss and hair strengthening shampoo in Example 1.

[0052] Participants: A total of 30 participants, including 8 males and 22 females, aged 22 to 55 years, with a mean age of 35.0 ± 9.8 years, who met the criteria for voluntary inclusion.

[0053] 2. Experimental Methods Subjects used the test product directly according to the usage characteristics and methods indicated on the cosmetic product label. Skin reactions were observed or followed up by telephone once a week. Results were recorded according to the grading standards for adverse skin reactions in human trials as outlined in the "Cosmetic Safety Technical Specifications" (2015 edition). The trial period was 4 weeks. Experimental results are shown in Table 5.

[0054] Table 5. Results of Human Safety Evaluation

[0055] Human trials showed that none of the 30 participants experienced adverse skin reactions.

[0056] Test Example 2: Mild (Non-irritating) Efficacy Evaluation 1. Experimental materials: ①The test sample was the anti-hair loss and hair strengthening shampoo in Example 1.

[0057] ② Chicken embryos: Use fertilized chicken embryos of Bai Lai Hang chickens. The quality of the chicken embryos must meet the relevant standards and requirements. The supplier should be a designated production enterprise of SPF eggs for veterinary drug production and inspection recognized by the agricultural department.

[0058] ③ Equipment: Incubator, clean bench.

[0059] 2. Experimental Indicators The endpoint score (ES) and irritation classification of the experimental samples are shown in Table 6.

[0060] Table 6. Endpoint Score (ES) and Stimuli Classification

[0061] 3. Experimental methods: ①Incubation conditions: Incubator temperature 37.5℃, relative humidity 60%.

[0062] ② Experimental controls: The negative control was a 0.9% sodium chloride solution, and the positive control was a 0.1 mol / L sodium hydroxide solution.

[0063] ③ Six embryos were used in each group, and one chicken embryo was set up for positive substance (reference substance) and solvent / carrier control.

[0064] ④ Remove 10-day-old chicken embryos, use an egg candler to examine the air cell and determine its location → use tweezers to peel off the upper part of the eggshell from the air cell, exposing the white eggshell membrane → add 0.15 mL of 0.9% sodium chloride solution to moisten the eggshell membrane → carefully remove the eggshell membrane with tweezers, and record the condition of the chorioallantoic membrane using a photographic device → spread 0.1 mL of the test substance onto the surface of a 1 cm diameter sterile plastic film to form a thin layer, and cover the central area of ​​the chorioallantoic membrane with it for 5 minutes → after the treatment, gently rinse the test substance on the chorioallantoic membrane with physiological saline (rinse 3 times, 5 mL each time), record the degree of chorioallantoic vascular damage using a photographic device, and score according to the degree of vascular damage. The experimental results are shown in Table 7.

[0065] Table 7. Evaluation Results of Mild (Non-irritating) Efficacy

[0066] Experimental results show that the anti-hair loss and hair strengthening shampoo in Example 1 is mild and non-irritating.

[0067] Test Example 3: Anti-hair loss efficacy test 1. Experimental Materials Test products: anti-hair loss and hair strengthening shampoos of Examples 1-3, Comparative Examples 1 and 3-4; control products were matrix-formulated products without Tibetan medicine compound compositions.

[0068] Participants: A total of 63 participants, including 6 males and 57 females, aged 19 to 60 years, with a mean age of 42.2 ± 10.4 years, meeting the criteria for voluntary inclusion.

[0069] Test equipment: The performance indicators of the dermatoscope met the requirements of the test specifications; the performance indicators of the comb met the requirements of the test specifications. The same specification and material of comb were used throughout the test. After each use, the comb was disinfected in accordance with the relevant requirements in the "Technical Specifications for Disinfection of Medical Institutions" (WS / T367-2012).

[0070] 2. Experimental Methods The testing was conducted according to the specific requirements of the "Cosmetic Safety Technical Specifications" (2015 edition). Subjects selected for the formal trial were randomly assigned to either the experimental product group or the control product group, with 9 subjects in each group. Pre-product hair follicle density was assessed in the subjects using a combing method (30 combing strokes per session, calculating the average number of hairs shed per subject per combing stroke; local hair density was measured using Photomax pro Trichoscan). The same tests were repeated after 12 weeks of product use. The test results are shown in Table 8.

[0071] Table 8 Results of the anti-hair loss efficacy test

[0072] Test Example 4: Anti-Hair Breakage Efficacy Test 1. Experimental Materials ① Test substance: The shampoos in Examples 1-3 and Comparative Examples 1-7.

[0073] ② Control group: blank control, treated with water.

[0074] ③ Experimental instrument: Hair comber: Model XJ810.

[0075] ④ Experimental materials: standard strands of real hair in vitro, 35cm-50cm in length, 25g / strand.

[0076] 2. Experimental Methods The samples were tested according to the specific requirements of the MC-ZY-167 hair breaking force test, and the same instrument and the same measuring personnel were used in the test process.

[0077] Preparation before the experiment: Select real hair of the same specifications and randomly divide them into experimental groups (Examples 1-3, Comparative Examples 1-7) and control groups. Each group has one bundle. Test the breaking strength of the hair. Each group should have at least 5 hairs for a single stretch test.

[0078] Experimental Measurement: The hair in the experimental group was pretreated according to the instructions for use of the tested samples. After wetting the hair strand with tap water, an appropriate amount of the shampoo of this invention was applied evenly to the hair strand. The hair was kneaded and washed in the direction from the ends to ensure it was not frizzy and was evenly treated for several minutes. It was then rinsed with water for 30 seconds before testing. The blank control group was treated with water and allowed to air dry. The tensile strength of the hair was measured again using the same method, and the results were recorded. The test results are shown in Table 9.

[0079] Table 9 Tensile force test results

[0080] Test Example 5: Nourishing (combing power, shine) efficacy test 1. Experimental Materials ① Test substances: Anti-hair loss and hair strengthening shampoos of Examples 1-3 and Comparative Examples 1-7.

[0081] ②The experiment was divided into a control group and an experimental group.

[0082] ③ Experimental instruments: Hair comber: Model XJ810; Gloss test probe: Model ETT200.

[0083] ④ Experimental materials: In vitro standard hair bundles (damaged hair) with a length of 35cm-50cm and about 25g / bundle; comb teeth density with a tooth spacing of 1.0mm, a tooth length of 2.2cm, and a comb length of 21.5cm (excluding the handle). The same specifications and materials of combs were used in the experiment.

[0084] 2. Experimental Methods ① The samples were tested according to the specific requirements of the MC-ZY-171 hair performance test (hair combing power and shine). The same instrument and the same measuring personnel were used in the test process.

[0085] ②Preparation before the experiment: Select real hair of the same specifications and randomly divide them into experimental group and control group, with 5 bundles in each group. Test the combing power and luster of the hair. Each bundle of hair was measured at least 3 times and the average value was taken.

[0086] ③ Experimental Measurement: Following the product's instructions, the experimental group's hair was treated as follows: After wetting the hair strand with tap water, an appropriate amount of the product was applied evenly to the hair strand. The hair was then kneaded and washed in the direction of hair growth, ensuring it remained frizz-free and evenly coated for several minutes. It was then rinsed with water for 30 seconds before testing. The control group received no treatment. After air drying, the hair's combability and shine were measured again using the same method, and the results were recorded. The test results are shown in Table 10.

[0087] Table 10 Results of Combing Strength and Gloss Tests

[0088] Test Example 6: Heat and Cold Resistance Test 1. Test sample: Anti-hair loss shampoo prepared in Examples 1-3.

[0089] 2. Test methods: The test sample was poured into three clean, dry test tubes, each 80 mm deep. One tube was placed in a 40°C incubator, and the other in a -5°C refrigerator. After 24 hours, the tubes were removed and allowed to return to room temperature. The samples were then compared with those in the third test tube to observe for any separation, precipitation, or discoloration. The test results are shown in Table 11.

[0090] Table 11 Results of heat and cold resistance tests

[0091] The above detailed description is a specific description of one of the feasible embodiments of the present invention. This embodiment is not intended to limit the patent scope of the present invention. All equivalent implementations or modifications that do not depart from the present invention should be included within the scope of the technical solution of the present invention.

Claims

1. A Tibetan medicine compound composition, characterized in that, The raw materials of the Tibetan medicine compound composition, by weight, include: 0.7-9 parts ginseng, 0.7-9 parts white fungus, 7-20 parts Polygonum multiflorum, 7-25 parts Platycladus orientalis leaves, 0.7-9 parts ginger, 0.7-9 parts wolfberry root, 0.7-9 parts eclipta prostrata, and 0.7-9 parts black sesame.

2. The Tibetan medicine compound composition according to claim 1, characterized in that, The preparation method of the Tibetan medicine compound composition includes: S1. Grind ginseng, white fungus, fleeceflower root, arborvitae leaves, ginger, wolfberry root, eclipta prostrata and black sesame seeds into powder, mix them, add water and decoct, filter, concentrate to obtain concentrated liquid; S2. Add ethanol to the concentrate, precipitate the alcohol, let it stand, recover the ethanol, concentrate, and the product is obtained.

3. The Tibetan medicine compound composition according to claim 2, characterized in that, In step S1, the amount of water added is 5-20 times the total mass of ginseng, white fungus, Polygonum multiflorum, Platycladus orientalis leaves, ginger, wolfberry root, Eclipta prostrata and black sesame. The decoction temperature is 85-95℃, the decoction time is 1.5-2.5h, the decoction is performed 1-2 times, and the relative density is 1.10-1.15 when concentrated to 25℃.

4. The Tibetan medicine compound composition according to claim 2, characterized in that, In step S2, ethanol is added to a volume concentration of 65%-85%, and the standing temperature is 2-6℃ for 10-30 hours, until no alcohol odor remains.

5. The use of the Tibetan medicine compound composition according to any one of claims 1-4 in the preparation of anti-hair loss and hair-strengthening shampoo.

6. A shampoo for preventing hair loss and strengthening hair, characterized in that, The raw materials of the anti-hair loss and hair strengthening shampoo include: water, moisturizer, conditioner, surfactant, stabilizer, chelating agent, pH adjuster, preservative, filler, and the Tibetan medicine compound composition according to any one of claims 1-4.

7. The anti-hair loss and hair-strengthening shampoo according to claim 6, characterized in that, The raw materials of the anti-hair loss and hair strengthening shampoo, by weight percentage, include: 1-3% moisturizer, 5-10% conditioning agent, 20-40% surfactant, 0.1-0.5% stabilizer, 0.3-0.8% chelating agent, 0.1-0.4% pH adjuster, 0.2-0.8% preservative, 0.1-0.3% filler, 1-10% Tibetan medicine compound composition, and the balance being water.

8. The anti-hair loss and hair-strengthening shampoo according to claim 6, characterized in that, The humectant is MOISOFTAM, the stabilizer is an acrylate / C10-30 alkanol acrylate crosspolymer, the chelating agent is hydroxyethyl diphosphate, the pH adjuster is citric acid, the preservative is phenoxyethanol, and the filler is titanium dioxide.

9. The anti-hair loss and hair-strengthening shampoo according to claim 6, characterized in that, The surfactant includes at least one of sodium lauryl ether sulfate, sodium dodecyl sulfate, cocamidopropyl betaine, amino acid surfactant, guar hydroxypropyltrimethylammonium chloride, and palm kernel oleamide DEA.

10. The anti-hair loss and hair-strengthening shampoo according to claim 6, characterized in that, The conditioning agents include adenosine, capryloyl glycine, cocamide MEA, behenamidopropyl dimethylamine, polydimethylsiloxane, hydroxypropyl methylcellulose, quaternary ammonium salt-82, PEG-8 diisostearate, and an anionic emulsion of polydimethylsiloxane, DOWSIL. TM At least one of 1785 POE Emulsion, natural active complex polypeptide hair conditioner ZS-PE-27B, and hydrolyzed wheat protein PG-propylsilanetriol.

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