A medicinal and edible composition for improving pet urinary health and a preparation method and application thereof

Abstract

This invention belongs to the field of pet urinary health technology, and specifically relates to a medicinal and edible homologous composition for improving pet urinary health. The composition comprises: Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel, and Juncus effusus, with a mass ratio of (4-6):(3-5):(2-4):(1-3):(0.5-1.5). This invention's medicinal and edible homologous composition is based on a systematic formulation concept, is scientifically sound, and selects medicinal and edible homologous raw materials with diuretic, urination-clearing, and water metabolism-regulating effects. The components work synergistically, significantly enhancing diuresis and urination efficiency, thus helping to improve the urinary health of pets.

Description

Technical Field

[0001] This invention belongs to the field of pet urinary health, and specifically relates to a food-medicine homology composition for improving pet urinary health, its preparation method, and its application. Background Technology

[0002] With the increasing popularity of pet ownership, dogs and cats have become the most important companion animals in modern society, and the number of pet dogs and cats in my country is growing year by year. Among the clinical disease spectrum in pets, urinary system diseases such as lower urinary tract syndrome and urinary tract stones have a persistently high incidence rate, becoming common problems affecting pets' health and quality of life. Current technologies often intervene in the pet's urinary environment, electrolyte metabolism, and urinary system health by reducing the concentration of added mineral ions in functional feeds or low-protein prescription diets, thereby regulating the urinary environment and reducing the urinary burden. However, these methods still have certain limitations in practical application. Simply relying on mineral ion regulation or urine acidification can easily lead to fluctuations in the urinary environment, and long-term feeding may affect the pet's overall metabolic balance, causing gastrointestinal symptoms or leading to the formation of insoluble calcium oxalate stones. While reducing protein content can alleviate the burden on the kidneys to some extent, it may not meet the cat's physiological needs and nutritional requirements for high-quality protein.

[0003] Food-grade medicinal ingredients are increasingly used in the field of pet urinary health due to their safety and lack of side effects. Current technologies mostly use single herbs or simple combinations, lacking a systematic approach based on traditional Chinese medicine theory. Single herbs have limited efficacy and cannot cover the complex causes of urinary system diseases; simple combinations do not consider the synergistic or antagonistic effects between components, resulting in limited overall effectiveness as diuretic, litholytic, anti-inflammatory, and anti-stress effects cannot be synergistically exerted. Furthermore, the application of food-grade medicinal active ingredients suffers from easy oxidation and degradation, poor palatability, and is easily deactivated during high-temperature processing.

[0004] In summary, existing technologies are insufficient to simultaneously address pet nutrition and urinary health, and the application of food-medicine homologous ingredients lacks stability. A new technological solution is urgently needed to fill the gaps in existing technologies. Summary of the Invention

[0005] To address the shortcomings of existing technologies, this invention provides a medicinal and edible homologous composition for improving pet urinary health and its preparation method. This composition uses scientifically formulated medicinal and edible homologous components as its core efficacy for the comprehensive maintenance of pet urinary system health; and employs composite wall material microencapsulation technology to encapsulate the functional components, thereby improving its processing and storage stability.

[0006] To achieve the above objectives, on the one hand, the present invention provides a medicinal and edible composition for improving the urinary health of pets, the medicinal and edible composition comprising: Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel and Juncus effusus, wherein the mass ratio of Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel and Juncus effusus is (4-6):(3-5):(2-4):(1-3):(0.5-1.5).

[0007] Furthermore, the mass ratio of Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel, and Juncus effusus is 5:4:3:2:1.

[0008] Furthermore, the medicinal and edible composition also contains lily and theanine, and the mass ratio of Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel, Juncus effusus, lily and theanine is (4-6):(3-5):(2-4):(1-3):(0.5-1.5):(0.5-1.5):(0.5-1.5).

[0009] Preferably, the mass ratio of Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel, Juncus effusus, lily bulb and theanine is 5:4:3:2:1:1:1.

[0010] Secondly, the present invention provides a food-medicine homology microcapsule for improving the urinary health of pets, comprising a core material and a wall material encapsulating the core material, wherein the mass ratio of the core material to the wall material is 1:(3-5); Preferably, the mass ratio of the core material to the wall material is 1:4; The core material is the above-mentioned food and medicine homology composition, and the wall material contains gelatin, maltodextrin and β-cyclodextrin, wherein the mass ratio of gelatin, maltodextrin and β-cyclodextrin is (1-3):(2-4):1; Preferably, the mass ratio of gelatin, maltodextrin, and β-cyclodextrin is 2:3:1.

[0011] Thirdly, the present invention provides a method for preparing the above-mentioned microcapsules, comprising the following steps: (1) Preparation of core material: The medicinal and edible homologous composition is made into powder; (2) Preparation of wall material solution: Dissolve gelatin, maltodextrin and β-cyclodextrin in water to prepare a wall material solution with a mass concentration of 8%-12%; (3) Emulsification and homogenization: The core material powder and the wall material solution are mixed and homogenized to form an emulsion; (4) Spray drying: The emulsion is spray dried and then sieved to obtain the microcapsules.

[0012] Further, in step (1), the medicinal and edible composition is composed of Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel and Juncus effusus. Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel and Juncus effusus are ultra-finely pulverized and passed through a 200-mesh sieve to obtain powder. They are then mixed evenly in a mass ratio of 5:4:3:2:1 to obtain core material powder.

[0013] Further, in step (2), gelatin, maltodextrin and β-cyclodextrin are mixed in a mass ratio of 2:3:1 and dissolved in deionized water to prepare a wall material solution with a mass concentration of 10%.

[0014] Further, in step (3), the core material powder is added to the wall material aqueous solution, stirred and dissolved in a 45°C water bath, and homogenized using a high-speed shear homogenizer to form a uniform and stable O / W type emulsion.

[0015] Furthermore, the high-speed shear homogenizer operates at a speed of 12,000 r / min and homogenizes for 20 min.

[0016] Further, in step (4), the emulsion is spray-dried with an inlet air temperature of 155-165°C and an outlet air temperature of 70-80°C to obtain the microcapsule product.

[0017] Further, in step (4), the emulsion is fed into a centrifugal spray dryer via a peristaltic pump. The inlet temperature is 160℃, the outlet temperature is 75℃, the feed rate is 15 mL / min, and the atomizing disc speed is 30000 r / min. After drying, the microcapsule product is collected and screened through a 100-mesh sieve to remove excessively large agglomerated particles, thereby obtaining microcapsule powder with uniform particle size.

[0018] Fourthly, the present invention provides a pet food for improving urinary health, comprising a base feed and functional components, wherein the functional components are the aforementioned food-medicine homology composition or the aforementioned microcapsules; the amount of the functional components added is 1%-5% of the total mass of the pet food, for example: 1%, 2%, 3%, 4%, 5%.

[0019] Furthermore, the basic feed includes animal protein raw materials, plant carbohydrate raw materials, oil raw materials, and vitamin and mineral premixes.

[0020] Specifically, the animal protein raw material is selected from one or more of fresh chicken, chicken products, and fish; the plant carbohydrate raw material is selected from one or more of potatoes, oats, buckwheat, and sweet potatoes; and the oil raw material is selected from one or two of fish oil and spirulina oil.

[0021] Furthermore, the pet food is dog food or cat food, preferably cat food.

[0022] Fifthly, the present invention provides the use of the aforementioned food-medicine homology composition or the aforementioned microcapsules in the preparation of products for improving the urinary health of pets.

[0023] Furthermore, the product is pet food or medicine.

[0024] Compared with the prior art, the present invention has the following advantages: (1) The food-medicine composition of the present invention is based on the concept of system compatibility, which is scientific and reasonable. It selects food-medicine raw materials with diuretic, urination-clearing and water metabolism-regulating effects: Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel and Juncus effusus. The efficacy of each component is complementary and the synergistic effect is significant. It has a significant promoting effect on the amount of urine excreted during animal feeding, effectively reduces the concentration of urine solutes and the specific gravity of urine, and makes the urine in a more diluted and fluid state. It helps to synergistically improve the physicochemical state of urine and reduce the risk of crystal formation, thereby improving the level of urinary health.

[0025] (2) When combined with Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel and Juncus effusus, lily and theanine can relieve pet stress response and achieve comprehensive effects of prevention, adjuvant treatment and stress relief, breaking through the limitations of existing single-herb or simple compounding techniques.

[0026] (3) The present invention uses a composite wall material composed of gelatin, maltodextrin and β-cyclodextrin, and a core material composed of food and medicine homology composition to prepare microcapsules through spray drying process. After microencapsulation treatment, the active ingredients of food and medicine homology can be effectively protected, and the oxidative degradation and heat loss during processing can be reduced. At the same time, the encapsulation characteristics of microcapsules help to reduce flavor volatilization and mask unpleasant odors, which is beneficial to improving the sensory quality of the product.

[0027] (4) When the food-medicine composition of the present invention is added as a functional component to high-protein pet food, it can effectively reduce renal function-related indicators such as serum creatinine and blood urea nitrogen, maintain the urinary health of pets, and while meeting the nutritional needs of high protein, the present invention has good renal function tolerance and feeding safety, and long-term feeding will not cause metabolic disorders. Attached Figure Description

[0028] Figure 1 The 24-hour urine output of rats after 3 days of gavage administration; Figure 2 The urine specific gravity of rats after 3 days of gavage administration; Figure 3 The plasma antidiuretic hormone concentration in rats after 3 days of gavage administration; Figure 4 To investigate the 24-hour urination volume of cats 28 days after intervention; Figure 5 To intervene in the specific gravity of cat urine 28 days later; Figure 6To intervene in the pH of cat urine 28 days later; Figure 7 To intervene in the cat's serum creatinine levels 28 days later; Figure 8 To intervene in the blood urea nitrogen status of cats 28 days later; Figure 9 Scoring the cat's mental state 28 days after the intervention; Figure 10 Assess the cat's activity level 28 days after the intervention; Figure 11 Appetite scores of cats 28 days after intervention; Figure 12 Bladder ultrasound findings in a cat with urinary stones after 45 days of feeding it a urinary diet. Detailed Implementation

[0029] The following detailed embodiments further illustrate the concept and technical effects of the present invention to fully understand its purpose, features, and effects. Unless otherwise specified, all methods described are conventional methods. Unless otherwise specified, all materials are available from publicly available commercial sources. The illustrative embodiments and descriptions of the present invention are used to explain the invention and do not constitute an undue limitation thereof. It should be noted that, unless otherwise specified, the embodiments and features described in the present invention can be combined with each other.

[0030] Unless otherwise specified, the experimental methods used in the following embodiments are conventional methods. Unless otherwise specified, the experimental materials used in the following embodiments are commercially available products.

[0031] Alisma plantago-aquatica was purchased from Zhongjing Pharmacy; Poria cocos was purchased from Zhongjing Pharmacy; Celery seeds were purchased from Zhongjing Pharmacy; The winter melon peel was purchased from Zhongjing Pharmacy; The rush pith was purchased from Zhongjing Pharmacy; The lilies were purchased from Zhongjing Pharmacy; Theanine was purchased from Shanghai Maclean Biochemical Technology Co., Ltd. Sodium chloride (NaCl) was purchased from Shanghai Maclean Biochemical Technology Co., Ltd. Gelatin (food grade, 120 bloom) was purchased from Shanghai Maclean Biochemical Technology Co., Ltd. Maltodextrin (DE value 20) was purchased from Shanghai Maclean Biochemical Technology Co., Ltd. β-Cyclodextrin was purchased from Shanghai Maclean Biochemical Technology Co., Ltd.

[0032] I. Evaluation of the diuretic effect of the composition Model establishment: Forty-eight male 6-week-old SD rats were selected and administered 8 mL / kg body weight of 5% (w / v) NaCl solution by gavage for three consecutive days to establish a water and sodium retention model.

[0033] Grouping and Intervention: Forty-eight successfully modeled rats were randomly divided into eight groups of six each, with a ninth group consisting of six 6-week-old male SD rats. During the modeling and intervention periods, all nine groups of rats had free access to food, fed a standardized maintenance diet. The drug-food homology substance was administered via gavage, dissolved in physiological saline, at a volume of 3 mL per rat. The grouping and gavage dosage for each group are detailed in Table 1. All rats were administered the drug via gavage once daily for three consecutive days.

[0034] Example 1: Gavage Composition of Food and Medicine Subjects administered via gavage: Water- and salt-loaded rats.

[0035] Oral administration dosage: Based on rat body weight, Alisma plantago-aquatica 1g / kg, Poria cocos 0.8g / kg, Celery seed 0.6g / kg, Winter melon peel 0.4g / kg, Juncus effusus 0.2g / kg, total dose 3g / kg.

[0036] Preparation of the food-medicine homology composition: Five food-medicine homology components, namely Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel, and Juncus effusus, were taken, ultra-finely pulverized and passed through a 200-mesh sieve. They were then mixed evenly in a mass ratio of Alisma plantago-aquatica: Poria cocos: celery seed: winter melon peel: Juncus effusus = 5:4:3:2:1 to obtain the food-medicine homology composition powder.

[0037] The prepared food-medicine homology composition was dissolved in 3 mL of physiological saline according to the above dosage, and the food-medicine homology suspension was administered by gavage using a traditional Chinese medicine gavage needle.

[0038] Example 2: Microcapsules of a food-medicine homology composition administered via gavage Subjects administered via gavage: Water- and salt-loaded rats.

[0039] Oral administration dosage: Based on rat body weight, Alisma plantago-aquatica 1g / kg, Poria cocos 0.8g / kg, Celery seed 0.6g / kg, Winter melon peel 0.4g / kg, Juncus effusus 0.2g / kg, total dose 3g / kg.

[0040] Preparation of food and medicine homology microcapsules: (1) Core material preparation: same as the food and medicine homology composition powder in Example 1; (2) Preparation of wall material solution: Gelatin, maltodextrin and β-cyclodextrin are mixed in a mass ratio of 2:3:1 and dissolved in deionized water to prepare a wall material solution with a mass concentration of 10%. (3) Emulsification and homogenization: The mass ratio of core material to wall material is 1:4; the core material powder is added to the wall material solution and stirred and dissolved in a 45°C water bath. Then, a high-speed shear homogenizer is used to homogenize for 20 min at a speed of 12000 r / min to form a uniform and stable O / W type emulsion. (4) Spray drying: The emulsion is fed into a centrifugal spray dryer via a peristaltic pump. The inlet temperature is 160℃, the outlet temperature is 75℃, the feed rate is 15 mL / min, and the atomizing disc speed is 30000 r / min. After drying, the microcapsule product is collected. (5) Post-processing: The microcapsule finished product is sieved through a 100-mesh sieve to remove excessively large agglomerated particles and obtain microcapsule powder with uniform particle size.

[0041] The prepared food-medicine homology microcapsules were dissolved in 3 mL of physiological saline according to the above dosage.

[0042] Comparative Example 1 Subjects of gavage administration: Water- and salt-loaded rats; Gavage dosage: 3 g / kg based on rat body weight; dissolve Alisma plantago-aquatica in 3 ml of physiological saline at the above dosage.

[0043] Comparative Example 2 Subjects of gavage administration: Water- and salt-loaded rats; Oral administration dosage: 3 g / kg based on rat body weight; dissolve Poria cocos in 3 ml of physiological saline at the above dosage.

[0044] Comparative Example 3 Subjects of gavage administration: Water- and salt-loaded rats; Gavage dosage: 3 g / kg based on rat body weight; dissolve celery seeds in 3 ml of physiological saline at the above dosage.

[0045] Comparative Example 4 Subjects of gavage administration: Water- and salt-loaded rats; Gavage dosage: 3g / kg based on rat body weight; dissolve winter melon peel in 3ml of physiological saline at the above dosage.

[0046] Comparative Example 5 Subjects of gavage administration: Water- and salt-loaded rats; Gavage dosage: 3 g / kg based on rat body weight; dissolve the rush pith in 3 ml of physiological saline at the above dosage.

[0047] Comparative Example 6: Model Control Group Subjects of gavage administration: Water- and salt-loaded rats; Gavage composition: 3 mL physiological saline (excluding food and medicine homology components).

[0048] Comparative Example 7: Blank Control Group Subjects administered via gavage: Normal rats; Gavage composition: 3 mL physiological saline (excluding food and medicine homology components).

[0049] Table 1. Grouping of rats in the water-salt load model experiment. After 3 days of gavage administration, the urine volume, specific gravity, and other indicators of rats in each group were measured, and venous blood was collected to determine the serum antidiuretic hormone concentration. The main physiological function of serum antidiuretic hormone is to promote the reabsorption of water in the distal convoluted tubule and collecting duct of the kidney. It can inhibit urine formation by enhancing the water reabsorption efficiency of the kidney, thereby inhibiting the urination response.

[0050] Depend on Figure 1-3 As can be seen, compared with Comparative Example 7 (blank control group), Comparative Example 6 (model control group) showed a significant decrease in 24-hour urine volume, a significant increase in urine specific gravity, and a significant increase in serum antidiuretic hormone concentration. These results demonstrate that water and salt loading inhibited urine formation in rats, reduced urine volume, led to urine concentration, and increased urine specific gravity, thus successfully establishing the model.

[0051] Compared with Comparative Examples 1-6, Examples 1 and 2 showed a significant increase in 24-hour urine output in rats, and a significant decrease in urine specific gravity and serum antidiuretic hormone concentration. This indicates that the five medicinal and edible components—Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel, and Juncus effusus—have complementary effects and a synergistic effect, significantly promoting urine output during feeding. Simultaneously, they make the urine more diluted and fluid, resulting in a significant enhancement of diuresis and urination. Therefore, the compositions in Examples 1 and 2 help synergistically improve the physicochemical state of urine and reduce the risk of crystal formation, thereby improving the urinary health of rats.

[0052] Compared to Example 1, the 24-hour urine output of rats in Example 2 was significantly increased, while urine specific gravity and serum antidiuretic hormone concentration were significantly decreased, indicating that the composition in Example 1, after microencapsulation, further enhanced the diuretic effect. This is because the composite wall material of gelatin, maltodextrin, and β-cyclodextrin, combined with the core material of the food-medicine homology composition, was prepared into microcapsules through a spray drying process. This effectively protected the active ingredients of the food-medicine homology and reduced oxidative degradation and heat-sensitive loss during processing. Simultaneously, the encapsulation properties of microcapsules help reduce the volatilization of flavor components and mask unpleasant odors, thus improving the sensory quality of the product.

[0053] II. Assessment of the impact of cat food containing compound ingredients on feline urinary health Fifteen cats aged 4-5 years with high urine specific gravity (urine specific gravity > 1.060, indicating a higher risk of urinary stones) were collected from a veterinary hospital and randomly divided into three groups of five cats each. The grouping details are shown in Table 2. All groups were fed 60 grams of food per day for 28 consecutive days.

[0054] Example 3: Feeding cats with a urinary tract infection caused by both food and medicine Feeding cats with a urinary tract infection-inducing diet that is both food and medicine, the preparation method of the urinary tract infection-inducing diet is as follows: (1) Preparation of basic cat food: Weigh 70 parts by weight of animal protein raw materials, which are selected from fresh chicken, chicken products, fish or a combination thereof; 15 parts by weight of plant carbohydrate raw materials, which are selected from potatoes, oats, buckwheat, sweet potatoes or a combination thereof; 10 parts by weight of oil raw materials, which are selected from fish oil and / or spirulina oil; and 5 parts by weight of vitamin and mineral premix. Mix the above raw materials, crush and mix them, and then add water to adjust the moisture content of the material to 25%. Then, send the adjusted material into the molding equipment for molding. During the extrusion molding process, the temperature is controlled at 112℃. After cooling, the temperature drops to below 40℃ to obtain the basic cat food. The nutritional components of the basic cat food are: crude protein content ≥40%, crude fat ≥18%, crude fiber ≤5%, crude ash ≤8%, and moisture ≤8%.

[0055] (2) Weigh 97 parts of basic cat food and 3 parts of the food-medicine composition in Example 1 by weight, and use vacuum spraying process to evenly spray the food-medicine composition onto the surface of the basic cat food.

[0056] Example 4: Feeding cats with a combination of medicinal and edible urinary tract and mood-soothing properties. Feeding cats with a urinary tract stimulating and mood-soothing formula using a food-medicine homology source, the preparation method of which is as follows: (1) Preparation of basic cat food: Same as in Example 3; (2) Preparation of food and medicine homology composition: Take Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel, Juncus effusus, and mood-soothing components lily bulb and theanine, a total of 7 food and medicine homology components, respectively, and after ultra-fine grinding, pass through a 200-mesh sieve, mix them evenly according to the mass ratio of Alisma plantago-aquatica: Poria cocos: celery seed: winter melon peel: Juncus effusus: lily bulb: theanine = 5:4:3:2:1:1:1 to obtain food and medicine homology composition powder; (3) Weigh 96.6 parts of basic cat food and 3.4 parts of the food-medicine composition by weight, and use a vacuum spraying process to evenly spray the food-medicine composition onto the surface of the basic cat food.

[0057] Comparative Example 8: Control group fed basal cat food Feed the basic cat food, and the preparation method is the same as the basic cat food preparation steps in Example 3 (1); Table 2 Grouping of the Pet Cat Urinary Health Assessment Test After 28 days, the 24-hour urine volume, urine specific gravity, urine pH, serum creatinine, and serum urea nitrogen concentration of each group of cats were measured. The mental state, activity level, and appetite of each group of cats were also scored, with a maximum score of 5 points; a higher score indicates a better condition. Specific evaluation criteria are shown in Table 3-5.

[0058] Table 3 Mental Status Scores The mental state score is the sum of the scores for each of the above items. Table 4 Activity Level Scoring Table 5 Appetite Score The results of urine volume, urine specific gravity, and urine pH after 28 days of feeding are as follows: Figure 4-6 As shown, compared with Comparative Example 8, Examples 3 and 4 showed a significant increase in 24-hour urine output and a significant decrease in urine specific gravity. The urine specific gravity value returned from the high-risk zone of urinary stones (above 1.060) to the normal low-risk zone (below 1.060), and the urine pH returned from an abnormally alkaline state to a normal slightly acidic state. These results indicate that the addition of the food-medicine homology composition is beneficial to the excretion of urine in cats, can reduce the risk of stone formation, and thus effectively improve the urinary health of cats.

[0059] Creatinine and blood urea nitrogen levels are important indicators for assessing renal function. The serum creatinine and blood urea nitrogen concentrations at the intervention endpoints for each group are shown below. Figure 7-8 As shown, by Figure 7-8 It can be seen that, compared with Comparative Example 8, the creatinine and urea nitrogen levels of cats in Examples 3 and 4 were significantly reduced, indicating that the food-medicine homology composition is beneficial to improving the renal health of cats.

[0060] The mental state, activity level, and appetite scores after 28 days of feeding are as follows: Figure 9-11 As shown, compared with Comparative Example 8, Example 3 showed a significant increase in the cat's mental state score, activity level score, and appetite score, indicating that the improvement in urinary health reduced the cat's discomfort and improved its mental state. In Example 4, after supplementing with the mood-regulating medicinal and edible components lily and theanine, the cat's mental state score, activity level score, and appetite score further increased compared with Example 3, indicating that the mood-soothing components helped to further improve the cat's mental state and improve the cat's overall health.

[0061] III. Feeding Experiment with Cats with Urinary Stones Cats in the acute phase of urinary stones were selected from a veterinary hospital, and their bladder stones were scanned by ultrasound. They were then fed the cat food described in Example 4. After 45 days of feeding, the degree of bladder stones was assessed by ultrasound, and the results were as follows: Figure 12As shown in the image, after 45 days of feeding, all large bladder stones in the patient's bladder disappeared, confirming that the cat food described in this invention has a significant alleviating effect on urinary stones.

[0062] The embodiments described above are only some embodiments of the present invention, not all embodiments. Other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative effort are all within the scope of protection of the present invention.

Claims

1. A medicinal and edible composition for improving urinary health in pets, characterized in that, The medicinal and edible composition includes the following components: Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel, and Juncus effusus, wherein the mass ratio of Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel, and Juncus effusus is (4-6):(3-5):(2-4):(1-3):(0.5-1.5).

2. The medicinal and edible composition as described in claim 1, characterized in that, The mass ratio of Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel, and Juncus effusus is 5:4:3:2:

1.

3. The medicinal and edible composition as described in claim 1, characterized in that, It also contains lily and theanine, and the mass ratio of Alisma plantago-aquatica, Poria cocos, celery seed, winter melon peel, rush pith, lily and theanine is (4-6):(3-5):(2-4):(1-3):(0.5-1.5):(0.5-1.5):(0.5-1.5).

4. A food-grade microcapsule for improving urinary health in pets, characterized in that, The invention comprises a core material and a wall material enclosing the core material, wherein the mass ratio of the core material to the wall material is 1:(3-5), the core material is a food-medicine homology composition as described in any one of claims 1 to 3, and the wall material comprises gelatin, maltodextrin and β-cyclodextrin, wherein the mass ratio of the gelatin, maltodextrin and β-cyclodextrin is (1-3):(2-4):

1.

5. A method for preparing the microcapsules as described in claim 4, characterized in that, Includes the following steps: (1) Preparation of core material: The medicinal and edible composition according to any one of claims 1-3 is made into powder; (2) Preparation of wall material solution: Dissolve gelatin, maltodextrin and β-cyclodextrin in water to prepare a wall material solution with a mass concentration of 8%-12%; (3) Emulsification and homogenization: The core material powder and the wall material solution are mixed and homogenized to form an emulsion; (4) Spray drying: The emulsion is spray dried and then sieved to obtain the microcapsules.

6. A pet food that improves urinary health, characterized in that, It comprises a basic feed and a functional component, wherein the functional component is the food-medicine homology composition according to any one of claims 1-3 or the microcapsule according to claim 4; the amount of the functional component added is 1%-5% of the total mass of the pet food.

7. The pet food as described in claim 6, characterized in that, The basic feed includes animal protein raw materials, plant carbohydrate raw materials, oil raw materials, and vitamin and mineral premix; the animal protein raw materials are selected from one or more of fresh chicken, chicken products, and fish; the plant carbohydrate raw materials are selected from one or more of potatoes, oats, buckwheat, and sweet potatoes; and the oil raw materials are selected from one or two of fish oil and spirulina oil.

8. The pet food as described in claim 6 or 7, characterized in that, The pet food mentioned is dog food or cat food.

9. The use of the food-medicine composition according to any one of claims 1-3 or the microcapsule according to claim 4 in the preparation of products for improving the urinary health of pets.

10. The application as described in claim 9, characterized in that, The product in question is either pet food or medicine.

Images