A mosla herb composition for removing dampness, invigorating spleen, refreshing brain and tranquilizing mind, a preparation method and application thereof

Abstract

The application provides a patchouli composition for removing dampness, invigorating the spleen, refreshing the brain and calming the nerves and a preparation method and application thereof, and belongs to the technical field of functional food. The composition comprises the following raw materials: patchouli, 10-20 parts; tuckahoe, 8-18 parts; bergamot, 5-15 parts; dried tangerine or orange peel, 3-10 parts; and fried licorice, 2-6 parts. The application takes five kinds of food-medicine homologous materials, namely, patchouli, tuckahoe, bergamot, dried tangerine or orange peel and fried licorice, as core effective components, realizes the synergistic effects of removing dampness and turbidity, invigorating the spleen and stomach, soothing the liver and regulating qi, refreshing the brain and calming the nerves through scientific proportioning, and can be prepared into various edible dosage forms such as granules, oral liquid and ointment, and is especially suitable for modern sub-healthy people with heavy dampness, weak spleen and stomach, emotional irritability, dizziness, poor appetite and heavy limbs, is mild and safe, has no side effects, is suitable for long-term conditioning, and belongs to the technical field of functional conditioning food with food-medicine homology.

Description

Technical Field

[0001] This invention relates to the field of functional food technology, specifically to a patchouli composition for dispelling dampness, strengthening the spleen, refreshing the mind, and calming the nerves, as well as its preparation method and application. Background Technology

[0002] With the fast pace of modern life, the prevalence of unhealthy lifestyle habits such as greasy and cold diets, sedentary lifestyles, and high stress levels, excessive dampness and weak spleen and stomach have become common sub-health issues, often accompanied by a chain of symptoms including irritability, dizziness, heaviness in the limbs, loss of appetite, and loose stools. Traditional Chinese medicine theory believes that "dampness trapping the spleen" leads to dysfunction of the spleen and stomach, which in turn affects the generation of qi and blood and metabolism, triggering a vicious cycle of "spleen deficiency and dampness accumulation - qi stagnation - restlessness." This not only affects daily work efficiency and quality of life, but long-term improper treatment may also induce problems such as chronic gastritis and chronic fatigue syndrome.

[0003] Currently, functional products targeting dampness removal, spleen strengthening, and emotional regulation mainly suffer from the following pain points: First, many products that simply remove dampness are cold in nature (such as Job's tears and winter melon peel), and long-term consumption can easily damage the spleen and stomach's yang energy, leading to "dampness removal harming the spleen," resulting in poor compatibility; Second, many products that simply strengthen the spleen are greasy and can impede the stomach (such as yam and fox nut), easily aggravating dampness retention and failing to achieve the effect of removing dampness; Third, existing compound formula products lack a scientific synergistic mechanism, failing to form a complete system of "dampness removal, spleen strengthening, qi regulation, and calming the mind." They either focus on removing dampness and strengthening the spleen while neglecting emotional regulation, or simply calm the mind without addressing the root cause of dampness and spleen deficiency, resulting in single efficacy and weak targeting; Fourth, some products have single dosage forms, bitter taste, or contain sedative ingredients from Western medicine, which can easily lead to dependence with long-term consumption and are not safe enough.

[0004] Currently, there is no scientifically formulated combination of five medicinal and edible ingredients—patchouli, poria cocos, bergamot, tangerine peel, and prepared licorice root—specifically designed for dispelling dampness, strengthening the spleen, refreshing the mind, and calming the nerves, while also being suitable for various dosage forms, industrial production, and a mild taste. Therefore, developing a patchouli composition with a scientifically formulated, clearly defined, mild, safe, and palatable composition suitable for long-term conditioning is crucial to addressing the limitations of existing technologies and meeting precise market demands. Summary of the Invention

[0005] The purpose of this invention is to provide a dampness-removing, spleen-strengthening, brain-awakening, and calming agastache composition, its preparation method, and its application. This addresses the problems of existing products that damage the spleen when removing dampness, are greasy when strengthening the spleen, have limited efficacy, limited dosage forms, poor taste, insufficient safety, and poor stability in industrial production. Using five medicinal and edible ingredients as core active components, this invention achieves synergistic effects of removing dampness and turbidity, strengthening the spleen and stomach, soothing the liver and regulating qi, and awakening the mind and calming the nerves through scientific formulation. It precisely improves sub-health symptoms such as excessive dampness, weak spleen and stomach, irritability, dizziness, and headache. Furthermore, the composition can be prepared into various edible dosage forms, with simple processing, good stability, suitability for industrial production, mild and safe, without side effects, and a pleasant taste, adaptable to different consumer scenarios and conditioning needs, and can be consumed long-term. Its application value in functional foods is also clearly defined.

[0006] To achieve the above-mentioned objectives, the present invention provides the following technical solution: This invention provides a patchouli composition for dispelling dampness, strengthening the spleen, refreshing the mind, and calming the nerves. By weight, it includes the following raw materials: patchouli: 10-20 parts, poria cocos: 8-18 parts, citron: 5-15 parts, tangerine peel: 3-10 parts, and prepared licorice root: 2-6 parts.

[0007] Preferably, by weight, it includes the following ingredients: 12-18 parts of patchouli, 10-16 parts of poria cocos, 8-12 parts of citronella, 5-8 parts of dried tangerine peel, and 3-5 parts of prepared licorice root.

[0008] The preparation method of the patchouli composition includes the following steps: taking patchouli, poria cocos, citron, tangerine peel, and prepared licorice, preparing extracts of each, passing them through an 80-100 mesh sieve, and mixing them with the excipients.

[0009] Preferably, the excipients are one or more of the following: fructooligosaccharides, resistant dextrin, steviol glycosides, citric acid, starch, magnesium stearate, and refined honey; The excipients are in the range of 500 to 5000 parts by weight.

[0010] Preferably, the dosage form of the composition is any one of granules, oral liquid, paste, capsules, or solid beverage.

[0011] Preferably, when the patchouli composition is in granule form, the preparation method further includes: mixing the extracts and excipients of the five raw materials until the uniformity is ≥98%, granulating and sizing the granules to a particle size of 10~30 mesh, and drying to a moisture content of ≤5% to obtain the finished granule product.

[0012] Preferably, when the patchouli composition is in the form of a paste, the preparation method further includes: mixing five extracts and excipients to a uniformity of ≥98%, adding 2 to 5 times the weight of the powder in water, concentrating at 50 to 60°C to a relative density of 1.20 to 1.25, adding 30 to 50 times the total weight of the raw materials in refined honey, continuing to stir until the refined honey is completely blended, and then cooling the paste to obtain the finished paste.

[0013] Preferably, when the patchouli composition is an oral liquid dosage form, the preparation method further includes: dissolving the excipients and the five extracts in water respectively, mixing them, filtering, and sterilizing at low temperature to obtain the finished oral liquid product.

[0014] The present invention also provides the application of the above-mentioned patchouli composition in the preparation of functional foods that dispel dampness, strengthen the spleen, and calm the mind.

[0015] The combination of five Chinese medicinal herbs in this invention achieves a synergistic effect of "removing dampness without being cold, strengthening the spleen without being greasy, regulating qi without depleting qi, and calming the mind without causing drowsiness," precisely targeting the core pathogenesis of "dampness trapping the spleen, qi stagnation, and restlessness." Among them, agastache, poria, bergamot, tangerine peel, and prepared licorice are all nationally recognized food and medicine homologous ingredients. Agastache is aromatic and clears away turbidity, harmonizes the stomach and stops vomiting, and releases exterior pathogens and relieves summer heat (core dampness-removing component); poria promotes diuresis and eliminates dampness, strengthens the spleen and calms the mind (core spleen-strengthening and mind-calming component); bergamot soothes the liver and regulates qi, harmonizes the stomach and relieves pain, and dries dampness and resolves phlegm (qi-regulating + auxiliary dampness-removing); tangerine peel regulates qi and strengthens the spleen, dries dampness and resolves phlegm (auxiliary spleen-strengthening + dampness-removing); and prepared licorice tonifies qi and replenishes the middle jiao, harmonizing the properties of the herbs (harmonizing the properties of the herbs and avoiding imbalance). Furthermore, the combination of agastache rugosa, poria cocos, and tangerine peel works synergistically to dispel dampness and strengthen the spleen, addressing the problem of "excessive dampness and spleen deficiency"; the combination of bergamot, tangerine peel, and prepared licorice root works synergistically to soothe the liver and regulate qi, addressing the problem of "qi stagnation"; and the combination of poria cocos and prepared licorice root works synergistically to calm the mind and soothe the nerves, addressing the problem of "restlessness". The five medicinal ingredients together achieve a synergistic effect of "dispelling dampness and turbidity, strengthening the spleen and stomach, soothing the liver and regulating qi, and refreshing the mind and calming the nerves". The medicinal properties are balanced, dispelling dampness without being cold, strengthening the spleen without being greasy, regulating qi without depleting qi, and calming the nerves without causing drowsiness, precisely improving symptoms such as heaviness in the limbs, dizziness, irritability, and loss of appetite.

[0016] Beneficial effects

[0017] (1) Synergistic effects and strong targeting: This invention closely follows the core pathogenesis of "dampness trapping the spleen, qi stagnation, and restlessness". The five medicinal and food ingredients work synergistically to remove dampness, strengthen the spleen, regulate qi, and calm the mind. It can accurately improve sub-health symptoms such as heavy dampness, weak spleen and stomach, irritability, dizziness and headache. It regulates the body constitution from the root. Compared with single-ingredient formulas or traditional compound formulas, the effects are more comprehensive and targeted. Moreover, the conditioning is gentle, does not relapse, and has no side effects.

[0018] (2) Mild and safe: All ingredients are nationally recognized food and medicine ingredients. The proportions have been scientifically optimized and the medicinal properties are balanced. It removes dampness without being cold, strengthens the spleen without being greasy, regulates qi without depleting qi, and calms the mind without causing drowsiness. It contains no harmful ingredients and avoids the problems of traditional dampness removal products damaging the spleen and calming the mind products causing drowsiness. It is suitable for long-term conditioning and is suitable for sub-healthy people with different constitutions.

[0019] (3) Suitable taste and high acceptance: By scientifically matching auxiliary materials, the slight astringency of the ingredients is harmonized to achieve a sweet and mild taste with a refreshing taste and no bitterness. It can be adjusted to a formula with 0 sucrose, 0 flavoring and 0 preservatives according to needs. It contains no sedative ingredients of Western medicine, which is suitable for the taste needs of the general public, improves product compliance, and facilitates long-term conditioning.

[0020] (4) Scientific process, suitable for multiple dosage forms: The preparation process is temperature controlled throughout to avoid loss of effective ingredients. The steps are simple and easy to operate. It can be prepared into a variety of dosage forms such as granules, oral liquids, and ointments, which are suitable for different consumption scenarios (home, office, business trip). It is suitable for large-scale industrial production, reducing production costs, while meeting the consumption habits of different groups of people.

[0021] (5) High application value: The core of this invention is to protect the combination formula, preparation method and application of five kinds of food and medicine ingredients, covering multiple dosage forms and multiple application scenarios, with high added value and great market potential. Detailed Implementation

[0022] The technical solutions provided by the present invention will be described in detail below with reference to the embodiments, but they should not be construed as limiting the scope of protection of the present invention.

[0023] Example 1

[0024] A combination of agastache rugosa for dispelling dampness, strengthening the spleen, refreshing the mind, and calming the nerves: by weight, agastache rugosa 15 parts, Poria cocos 12 parts, Citrus medica 10 parts, Citrus reticulata 6 parts, and Glycyrrhiza uralensis 4 parts.

[0025] Example 2

[0026] A combination of agastache rugosa for dispelling dampness, strengthening the spleen, refreshing the mind, and calming the nerves: by weight, 12 parts agastache rugosa, 10 parts poria cocos, 8 parts citronella citron, 5 parts tangerine peel, and 3 parts prepared licorice root.

[0027] Example 3

[0028] A composition of agastache rugosa for dispelling dampness, strengthening the spleen, refreshing the mind and calming the nerves: by weight, 15 parts agastache rugosa, 12 parts poria cocos, 10 parts citronella citron, 6 parts tangerine peel and 4 parts prepared licorice root.

[0029] Example 4: Preparation of Granules

[0030] 1. Raw material preparation: Prepare the Chinese herbal raw materials according to the formula in Example 1. In addition, prepare 2400 parts of fructooligosaccharide, 500 parts of resistant dextrin, 60 parts of citric acid and 40 parts of steviol glycoside as excipients, by weight.

[0031] 2. Pretreatment: After pulverizing the agastache, poria cocos, citron, tangerine peel, and prepared licorice root separately, extract them at a ratio of 10:1 to prepare extracts. Pass all extracts and excipients through a 100-mesh sieve to remove impurities, ensuring that the raw materials are fine and uniform and easy to mix. Store the five-ingredient extracts in a cool, dry environment at 22℃ and 50%RH, away from light, to prevent oxidation of the active ingredients and ensure stable efficacy.

[0032] The preparation method of the patchouli extract is as follows: using acetone as the extraction solvent, the material-to-liquid ratio is 1g:10mL, soaking for 10min, ultrasonic extraction at 40KHz for 1.5 hours, adding to a saturated β-cyclodextrin solution, stirring at 50℃ for 40min, and drying at 50℃ to obtain the patchouli extract. The preparation method of Poria cocos extract is as follows: according to the material-liquid ratio of 1g:10mL, water is added to the pulverized Poria cocos and soaked for 30min, microwave extraction is performed at 500W for 10min, filtered through a 0.22μm microporous membrane, ethanol is added to a final concentration of 80%, and the mixture is allowed to stand overnight at 4℃. After centrifugation at 3000rpm for 10min, the precipitate is taken and freeze-dried at -40℃ to obtain Poria cocos extract. The preparation method of the extract of Buddha's Hand is as follows: according to the material-liquid ratio of 1g:10mL, water is added to the crushed Buddha's Hand and soaked for 30min, steam distillation is carried out for 8h, the volatile oil is collected, added to a saturated β-cyclodextrin solution, stirred at 50℃ for 40min, and dried at 50℃ to obtain Buddha's Hand volatile oil powder. After the volatile oil extraction residue was dried, 70% ethanol was added and mixed at a material-to-liquid ratio of 1:15. The mixture was extracted at 60℃ and 420W for 40 minutes by ultrasonication. The residue was filtered and the filtrate was collected. The extraction was repeated twice. The filtrates were combined and concentrated under reduced pressure at 50℃ and -0.1MPa to a density of 1.15. The residue was then dried under vacuum at 60℃ and -0.09MPa and mixed with bergamot volatile oil powder to obtain bergamot extract. The preparation method of the extract of dried tangerine peel is as follows: according to the material-liquid ratio of 1g:10mL, water is added to the pulverized dried tangerine peel and soaked for 30min, steam distillation is carried out for 6h, the volatile oil of dried tangerine peel is collected, and the volatile oil powder is obtained by β-cyclodextrin encapsulation technology; the residue after volatile oil extraction is dried and then 35% ethanol is added for extraction (same as the extraction process of Buddha's Hand), and the solid powder is obtained. After mixing with the volatile oil powder of dried tangerine peel, the extract of dried tangerine peel is obtained. The method for extracting licorice root is as follows: add water to the pulverized licorice root and decoct for 2 hours according to the material-to-liquid ratio of 1g:10mL, filter, collect the filtrate, repeat the extraction once, combine the filtrates, concentrate at 50℃ and -0.1MPa reduced pressure to a density of 1.20, and dry at 60℃ to obtain the licorice root extract. 3. Mixing: Take the extracts of the five Chinese herbal raw materials and mix them for 12 minutes using the equal-increment method. Then add fructooligosaccharides, resistant dextrin, citric acid, and steviol glycosides and mix for a total of 20 minutes to ensure that the mixing uniformity is ≥98%.

[0033] 4. Granulation: Dry roller pressing granulation process is adopted to obtain 20 mesh granules, which are dried to a moisture content of ≤5%, and lumps and fine powder are removed after granulation.

[0034] 5. Packaging: The product is packaged in aluminum foil bags at 10g / bag specifications and sealed to obtain the finished granules. The finished product is stored in a cool and dry environment and has a shelf life of 18 months.

[0035] Example 5 Preparation of oral liquid

[0036] 1. Raw material preparation: Prepare the Chinese herbal raw materials according to the formula in Example 1. In addition, prepare 2400 parts of fructooligosaccharide, 500 parts of resistant dextrin, 60 parts of citric acid, 40 parts of steviol glycoside (by weight) and 27000 parts of purified water (for 30ml / vial).

[0037] 2. Pretreatment: Agastache rugosa, Poria cocos, Citrus medica, Citrus reticulata peel, and Glycyrrhiza uralensis were prepared into extracts. All extracts and excipients were passed through a 100-mesh sieve to remove impurities, ensuring that the raw materials were fine and uniform and easy to mix.

[0038] 3. Dissolving: Take purified water, control the temperature at 35℃, add fructooligosaccharides, resistant dextrin, citric acid, and steviol glycosides, stir for 15 minutes until completely dissolved to obtain the excipient solution.

[0039] 4. Mixing: Add the extracts of the five flavor ingredients to the excipient solution, stir for 18 minutes to ensure complete dissolution, and obtain a mixed solution.

[0040] 5. Filtration: Filter the mixed solution through a 0.22μm filter membrane to obtain a clear solution.

[0041] 6. Filling and sterilization: Fill in 30ml / vial and sterilize at 45℃ for 30 minutes to avoid loss of active ingredients.

[0042] 7. Packaging: After filling, seal, label, and pack into boxes to obtain the finished oral liquid product; store the finished product in a low-temperature, light-protected environment at 2~8℃, with a shelf life of 18 months.

[0043] Example 6: Preparation of the herbal paste

[0044] 1. Raw material preparation: Prepare Chinese herbal raw materials according to the formula in Example 3, and also prepare 1800 parts (by weight) of molasses and 1000 parts of purified water.

[0045] 2. Pretreatment: After the extracts of the five flavor ingredients are pulverized separately to prepare extracts, they are all passed through a 100-mesh sieve along with the excipients to remove impurities, ensuring that the raw materials are fine and uniform and easy to mix.

[0046] 3. Mixing: Take the extracts of the five flavor ingredients and mix them for 18 minutes using the equal-increment method to ensure that the mixing uniformity is ≥98%.

[0047] 4. Concentration: Add purified water to the mixed extract, place it in a jacketed kettle and concentrate over a low flame (temperature 55℃), stirring constantly, until it becomes a thick paste (relative density 1.22, measured at 25℃).

[0048] 5. Concentration and Packaging: Add refined honey to the thick paste and continue stirring for 20 minutes until the honey is completely incorporated. After cooling, dispense into sterile glass bottles (250g / bottle), seal, and store in a cool, dry environment. Shelf life is 18 months.

[0049] Comparative Example 1

[0050] Unlike Example 4, the raw materials lacked patchouli.

[0051] Comparative Example 2

[0052] Unlike Example 4, the raw materials lacked Poria cocos.

[0053] Comparative Example 3

[0054] Unlike Example 4, Poria cocos in the formula was replaced with an equal amount of stir-fried Job's tears.

[0055] Comparative Example 4

[0056] Unlike Example 4, the Buddha's Hand citron in the formula was replaced with an equal amount of citron.

[0057] Experiment Example 1: Efficacy Verification Experiment

[0058] 240 sub-healthy volunteers, aged 20-55, were selected and randomly divided into groups of 40 each. All volunteers had symptoms such as excessive dampness (heaviness in the limbs, loose stools), weak spleen and stomach (loss of appetite, abdominal distension), irritability, dizziness, and headache. Pregnant women, breastfeeding women, people with allergies, and those with serious liver and kidney diseases or mental illnesses were excluded.

[0059] 1. Experimental group: Take one sachet (10g) of the granules prepared in Example 4 of this invention daily, dissolved in warm water, for 30 consecutive days.

[0060] 2. Control group 1: Take the granules provided in control group 1, in the same way as the experimental group.

[0061] 3. Control group 2: Take the granules provided in control group 2, in the same way as the experimental group.

[0062] 4. Comparative Example 3: Take the granules provided in Comparative Example 3, in the same manner as the experimental group.

[0063] 5. Comparative Example 4: Take the granules provided in Comparative Example 4, in the same manner as the experimental group.

[0064] 6. Control group: No functional conditioning products were taken, normal diet was maintained, and observation was carried out for 30 consecutive days.

[0065] After the experiment, the symptom improvement of each group of volunteers was statistically analyzed, including: improvement rate of dampness (relieving heaviness in limbs and loose stools), improvement rate of spleen and stomach function (relieving loss of appetite and abdominal distension), improvement rate of irritability, and improvement rate of dizziness and headache. The overall improvement rate was calculated as follows: improvement rate of each indicator = number of people who improved after intervention / total number of people × 100%. The overall improvement rate is the average improvement rate of the four indicators.

[0066] Table 1 Symptom Improvement

[0067] The experimental group showed significantly better improvement in symptoms such as dampness, spleen and stomach dysfunction, irritability, dizziness, and headache than the control groups 1-4 and the blank group. This proves that the five ingredients in the formula of this invention have a significant synergistic effect, and none of them can be omitted. They can effectively achieve the core effects of removing dampness, strengthening the spleen, refreshing the mind, and calming the nerves, accurately improving the sub-health problems of modern people. Moreover, the product is mild and non-irritating, and suitable for long-term conditioning.

[0068] Experimental Example 2

[0069] The products prepared in Example 4 (granules), Example 5 (oral liquid, 30ml / vial), and Example 6 (medicinal paste, 250g / bottle) were stored for 18 months under corresponding storage conditions (granules and medicinal pastes were stored in a cool, dry place, and oral liquids were stored at 2-8℃ in a low-temperature, light-protected place). Key indicators of the products were tested at 0 months and 18 months to verify product stability. The results are as follows: Stability of active ingredient content = Ending active ingredient content at the storage period / Labeled amount × 100%, with the initial (0 months) active ingredient content as the labeled amount. The active ingredients are the most unstable components, such as baicalein (representing patchouli) and hesperidin (representing bergamot and tangerine peel), as the main indicators, and are determined by gas chromatography.

[0070] Table 2 Product Stability Indicators

[0071] Experiments have shown that the granules, oral liquids, and pastes prepared from the composition of this invention exhibit minimal changes in the content of active ingredients (retention rate ≥91%) within their respective shelf lives, with no significant changes in taste or state. They demonstrate excellent stability in industrial production and can meet the needs of market circulation and long-term conditioning.

[0072] The above description is only a preferred embodiment of the present invention. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the principle of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A patchouli composition for dispelling dampness, strengthening the spleen, refreshing the mind, and calming the nerves, characterized in that, By weight, it includes the following ingredients: Patchouli: 10-20 parts, Poria cocos: 8-18 parts, Citrus medica: 5-15 parts, Citrus reticulata peel: 3-10 parts, and Glycyrrhiza uralensis: 2-6 parts.

2. The patchouli composition according to claim 1, characterized in that, By weight, it includes the following ingredients: 12-18 parts of patchouli, 10-16 parts of poria cocos, 8-12 parts of citronella, 5-8 parts of dried tangerine peel, and 3-5 parts of prepared licorice root.

3. A method for preparing the patchouli composition according to claim 1 or 2, characterized in that, Includes the following steps: Take agastache rugosa, poria cocos, citronella cirrhosa, tangerine peel and prepared licorice root, prepare extracts separately, pass them through an 80-100 mesh sieve, and mix them with excipients.

4. The preparation method according to claim 3, characterized in that, The excipients are one or more of the following: fructooligosaccharides, resistant dextrin, steviol glycosides, citric acid, starch, magnesium stearate, and refined honey; the excipients are in the range of 500 to 5000 parts by weight.

5. The preparation method according to claim 4, characterized in that, The dosage form of the patchouli composition is any one of granules, oral liquid, ointment, capsules, or solid beverage.

6. The preparation method according to claim 5, characterized in that, When the patchouli composition is in granule form, the preparation method further includes: mixing the extracts and excipients of the five raw materials until the uniformity is ≥98%, granulating and sizing the granules to a particle size of 10~30 mesh, and drying to a moisture content of ≤5% to obtain the finished granule product.

7. The preparation method according to claim 5, characterized in that, When the patchouli composition is in the form of a paste, the preparation method further includes: mixing five extracts and excipients until the uniformity is ≥98%, adding 2 to 5 times the weight of water of the powder, concentrating at 50 to 60°C to a relative density of 1.20 to 1.25, adding 30 to 50 times the weight of refined honey of the raw materials, continuing to stir until the refined honey is completely blended, collecting the paste and cooling it to obtain the finished paste.

8. The preparation method according to claim 5, characterized in that, When the patchouli composition is an oral liquid dosage form, the preparation method further includes: dissolving the excipients and the five extracts in water respectively, mixing them, filtering, and sterilizing at low temperature to obtain the finished oral liquid product.

9. The use of the patchouli composition according to any one of claims 1 to 4 in the preparation of functional foods for removing dampness, strengthening the spleen, refreshing the mind, and calming the nerves.

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