A neurology cerebrospinal fluid sampling and testing device
By using the gas pressure inside the reverse thrust mechanism to push the remaining liquid in the infusion tube back into the sampling cylinder, the problem of the distance between the liquid level in the cerebrospinal fluid sampler and the expected liquid level is solved, thus replenishing the sample concentration and ensuring the accuracy of the test results.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- NINGBO MEDICAL CENT LIHUILI HOSPITACL
- Filing Date
- 2026-05-08
- Publication Date
- 2026-06-05
AI Technical Summary
In existing technologies, air is drawn into the cerebrospinal fluid sampler during the extraction process, resulting in a lower-than-expected amount of cerebrospinal fluid being extracted, which affects the accuracy of the test results.
The gas pressure inside the reverse thrust mechanism pushes the remaining fluid in the infusion tube back into the sampling cylinder. Through the cooperation of the piston handle and the reverse thrust mechanism, the cerebrospinal fluid in the replenishment area is filled, ensuring the sample concentration.
The concentration of the cerebrospinal fluid sample was increased, ensuring the accuracy of the test results.
Smart Images
Figure CN122140295A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of detection technology for auxiliary diagnosis of neurological diseases, and more specifically, to a neurological cerebrospinal fluid sampling and detection device. Background Technology
[0002] Cerebrospinal fluid (CSF) is a transparent fluid found between the ventricles, spinal canals, and meninges of the brain, serving a buffering and protective function. It provides nutrients to the brain and spinal cord, removes metabolic waste, and maintains stable intracranial pressure. Abnormal changes in CSF are often associated with neurological diseases. The hydrogen sulfide content in CSF is a reference for diagnosing various diseases; therefore, sampling and testing devices are used to measure the hydrogen sulfide content in CSF.
[0003] In existing technologies, cerebrospinal fluid is often extracted using a sampling syringe and then injected into a detection device for testing, in order to measure the hydrogen sulfide content in the cerebrospinal fluid.
[0004] Because the sampler is connected to a needle at the front end, and there is a certain distance between the sampler and the needle tip, when extracting cerebrospinal fluid, the sampler will first draw in a section of air, and then the cerebrospinal fluid will be drawn into the sampler. This results in the actual amount of cerebrospinal fluid extracted being lower than expected; that is, there is a distance between the cerebrospinal fluid level and the expected level line, resulting in insufficient concentration of the final sample and affecting the accuracy of the test results. Summary of the Invention
[0005] This invention provides a cerebrospinal fluid sampling and testing device for neurology. It utilizes the gas pressure within a back-push mechanism to push the residual fluid in the infusion tube back into the sampling cylinder, thereby filling the gap in the cerebrospinal fluid in the replenishment area. This solves the problem mentioned in the background art, namely, that there is a distance between the cerebrospinal fluid level and the expected level line, resulting in insufficient concentration of the final sample and affecting the accuracy of the test results.
[0006] To achieve the above objectives, a neurological cerebrospinal fluid sampling and testing device includes a sampling cylinder, an end cap, a piston handle, and an infusion tube connected to the sampling cylinder. The end of the infusion tube has a needle. A reverse thrust mechanism is provided outside the sampling cylinder to connect the top of the sampling cylinder to the infusion tube. When the piston handle draws in cerebrospinal fluid, the piston handle pushes the gas in the sampling cylinder into the reverse thrust mechanism for storage. When the piston handle reaches a preset liquid level, a replenishment zone is formed between the preset liquid level and the cerebrospinal fluid level. The gas in the reverse thrust mechanism is released to the end of the infusion tube to drive the remaining liquid in the infusion tube to be supplied to the sampling cylinder to fill the vacant cerebrospinal fluid in the replenishment zone.
[0007] A drain pipe connected to the replenishment area is provided on one side of the sampling tube, and a second valve is provided on the drain pipe.
[0008] The lower edge of the connection between the drain pipe and the replenishment area is flush with the preset liquid level.
[0009] The reverse thrust mechanism includes a gas collection bag that is connected to the inside of the sampling cylinder and is used for gas collection. One end of the gas collection bag is connected to the sampling cylinder by a gas supply pipe, and the other end is connected to the end of the infusion pipe by a gas supply pipe. A first valve is provided on the gas supply pipe near the gas collection bag.
[0010] The end cap is provided with an air inlet pipe that communicates with the inside of the sampling cylinder. Both the air inlet pipe and the air supply pipe are provided with a first one-way valve. The first one-way valve located in the air supply pipe is used to supply gas from the sampling cylinder to the air supply pipe, and the first one-way valve located in the air inlet pipe is used to supply external gas to the sampling cylinder.
[0011] One side of the infusion tube is connected to an air intake manifold, and the air intake manifold is detachably connected to the end of the infusion tube.
[0012] A second one-way valve is provided at the end of the infusion tube. The second one-way valve is located in the horizontal direction below the connection between the infusion tube and the air intake manifold, and is used to supply cerebrospinal fluid into the sampling tube.
[0013] When gas is introduced into the infusion tube through the gas collection bag, the pressure inside the infusion tube increases, pushing the residual cerebrospinal fluid in the infusion tube back into the sampling tube.
[0014] Compared with the prior art, the beneficial effects of the present invention are as follows: In this neurology cerebrospinal fluid sampling and testing device, the piston handle and the reverse thrust mechanism work together to first collect the gas in the sampling cylinder into the reverse thrust mechanism for storage. Then, the gas pressure in the reverse thrust mechanism is used to push the remaining liquid in the infusion tube back into the sampling cylinder, thereby filling the gap in the cerebrospinal fluid in the replenishment area, thus increasing the final cerebrospinal fluid sample concentration and ensuring the accuracy of the test results. Attached Figure Description
[0015] Figure 1 This is a schematic diagram of the overall structure of the present invention; Figure 2 This is a schematic diagram of the connection structure between the sampling cylinder and the gas collection bag of the present invention; Figure 3 This is a schematic diagram of the piston handle movement structure of the present invention; Figure 4 This is a schematic diagram of the cerebrospinal fluid level difference inside the sampling tube of the present invention; Figure 5 For the present invention Figure 4 Enlarged structural diagram at point A in the diagram; Figure 6 This is a schematic diagram of cerebrospinal fluid flow within the infusion tube of the present invention; Figure 7This is a schematic diagram of the gas collecting bag of the present invention being inflated into the infusion tube.
[0016] The meanings of the labels in the diagram are as follows: 100. Sampling cylinder; 101. End cap; 102. Piston handle; 103. Infusion tubing; 104. Needle; 105. Air inlet tube; 106. Air inlet manifold; 107. Second check valve; 110. Detection kit; 120. Reverse thrust mechanism; 121. Gas collection bag; 122. Gas supply pipe; 123. Gas delivery pipe; 124. First valve; 125. First check valve; 130. Drain pipe; 131. Second valve. Detailed Implementation
[0017] The technical solutions of this invention will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this invention, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of this invention without creative effort are within the scope of protection of this invention.
[0018] Therefore, to address the problem that the cerebrospinal fluid level in the sampling tube 100 is lower than the expected level, this invention provides a cerebrospinal fluid sampling and detection device for neurology, referencing... Figure 1 As shown, the device includes a sampling cylinder 100, an end cap 101, a piston handle 102, and an infusion tube 103 connected to the sampling cylinder 100. The infusion tube 103 has a needle 104 at its end. When sampling cerebrospinal fluid, the sampling cylinder 100 is first fixed by a support to keep the sampling cylinder 100 in place. Figure 1 In the indicated state, the piston handle 102 is pulled to draw cerebrospinal fluid from the patient's brain into the sampling cylinder 100 through the needle 104, and then the piston handle 102 is pushed back to inject the cerebrospinal fluid into the detection box 110 in order to measure the hydrogen sulfide content in the cerebrospinal fluid.
[0019] Specifically, such as Figure 2 , Figure 3 As shown, a reverse thrust mechanism 120 is provided outside the sampling cylinder 100, connecting the top of the sampling cylinder 100 to the infusion tube 103. When the piston handle 102 draws in cerebrospinal fluid, the piston handle 102 pushes the gas in the sampling cylinder 100 into the reverse thrust mechanism 120 for storage. When the piston handle 102 reaches the preset liquid level, a replenishment zone is formed between the preset liquid level and the cerebrospinal fluid level. The gas in the reverse thrust mechanism 120 is released to the end of the infusion tube 103 to drive the remaining liquid in the infusion tube 103 to be supplied to the sampling cylinder 100 to fill the empty cerebrospinal fluid in the replenishment zone. That is, when the piston handle 102 reaches the preset liquid level height, the piston handle 102 corresponds to the h2 scale line, and at this time, due to... Figure 2The presence of air in the infusion tube 103 prevents the liquid level drawn into the sampling cylinder 100 from reaching the height of h2. That is, the cerebrospinal fluid level in the sampling cylinder 100 is the scale line h1.
[0020] Therefore, in order to expel air from the replenishment area, and in combination with Figure 4 , Figure 5 As shown, the replenishment area corresponds to the height difference h3 between h1 and h2. A drain pipe 130 connected to the replenishment area is provided on one side of the sampling cylinder 100. The lower edge of the drain pipe 130 where it connects to the replenishment area is flush with the preset liquid level. A second valve 131 is provided on the drain pipe 130. Thus, when the piston handle 102 draws in cerebrospinal fluid, the second valve 131 is in the closed state. The upward movement of the piston handle 102 will not allow the air above it to be discharged from the drain pipe 130. The second valve 131 restricts the emission of gas. Conversely, when the cerebrospinal fluid in the sampling cylinder 100 is drawn in from the drain pipe 130, the second valve 131 is closed. Figure 3 When the height h1 rises above the height h2, the second valve 131 is in the open state. On the one hand, the rising cerebrospinal fluid fills the replenishment area, so that the cerebrospinal fluid in the sampling cylinder 100 can reach the preset liquid level height. On the other hand, the excess cerebrospinal fluid rises and is discharged from the drain pipe 130 until the cerebrospinal fluid in the sampling cylinder 100 no longer flows out of the drain pipe 130. At this time, the cerebrospinal fluid in the sampling cylinder 100 is maintained at the preset liquid level height.
[0021] Now let's return to... Figure 2 As shown, the reverse thrust mechanism 120 includes a gas collection bag 121 connected to the sampling cylinder 100 for gas collection. The gas collection bag 121 is made of elastic material. One end of the gas collection bag 121 is connected to the sampling cylinder 100 by a gas supply pipe 122. When the piston handle 102 moves upward, the air in the sampling cylinder 100 is pushed into the gas collection bag 121 by the piston handle 102 through the gas supply pipe 122. The other end of the gas collection bag 121 is connected to the end of the infusion tube 103 by a gas supply pipe 123. A first valve 124 is provided on the gas supply pipe 123 near the gas collection bag 121. When cerebrospinal fluid is drawn, the first valve 124 is closed. Figure 3 In the middle, the end cap 101 is provided with an air inlet pipe 105 that communicates with the inside of the sampling cylinder 100. Both the air inlet pipe 105 and the air supply pipe 122 are provided with a first one-way valve 125. The first one-way valve 125 located in the air supply pipe 122 is used to supply gas from the sampling cylinder 100 to the air supply pipe 122, and the first one-way valve 125 located in the air inlet pipe 105 is used to supply external gas to the sampling cylinder 100.
[0022] Working principle: When the piston handle 102 moves upward, the first one-way valve 125 in the air inlet pipe 105 is closed, and the first one-way valve 125 in the air supply pipe 122 is open. At this time, under the action of the piston handle 102, the gas in the sampling cylinder 100 is transported to the gas collection bag 121, and the first valve 124 is also closed. In this way, the gas is stored in the gas collection bag 121. Conversely, when the piston handle 102 moves downward, the first one-way valve 125 in the air supply pipe 122 is closed, and the first one-way valve 125 in the air inlet pipe 105 is opened. External gas enters the sampling cylinder 100 through the air inlet pipe 105 to ensure the normal movement of the piston handle 102.
[0023] Furthermore, in combination Figure 6 As shown, Figure 6 The diagram illustrates the process of drawing cerebrospinal fluid using the infusion tubing 103. During this process, the cerebrospinal fluid flows within the infusion tubing 103. At this time, an air intake manifold 106 is connected to one side of the infusion tubing 103, and the air intake manifold 106 is detachably connected to the end of the air supply tubing 123. Furthermore... Figure 2 The first valve 124 is closed, so the cerebrospinal fluid in the infusion tube 103 will not flow into the gas infusion tube 123, but will be transported to the sampling cylinder 100 through the infusion tube 103.
[0024] On the other hand, based on Figure 6 Based on and combined Figure 7 As shown, after the cerebrospinal fluid extraction is completed, first... Figure 5 The second valve 131 is opened, and then... Figure 7 When the first valve 124 in the middle is opened, since the gas collection bag 121 is in an expanded state and the internal pressure is high, compressed gas is delivered into the infusion tube 103 through the gas delivery tube 123 and the air intake manifold 106 at the moment of opening, so as to replenish the residual cerebrospinal fluid in the infusion tube 103 into the sampling cylinder 100. Therefore, a second one-way valve 107 is provided at the end of the infusion tube 103. The second one-way valve 107 is located horizontally below the connection between the infusion tube 103 and the air intake manifold 106. In this way, when cerebrospinal fluid is extracted, the second one-way valve 107 is in the open state, and at this time, the second one-way valve 107 is used to supply cerebrospinal fluid into the sampling cylinder 100. Conversely, when the extraction of cerebrospinal fluid is stopped, the gas in the gas collection bag 121 is released into the infusion tube 103, the second one-way valve 107 is in the closed state, and there is residual liquid in the infusion tube 103. When the gas collection bag 121 introduces gas into the infusion tube 103, the gas will accumulate in the infusion tube 103, causing the pressure in the infusion tube 103 to rise, so as to push the residual cerebrospinal fluid in the infusion tube 103 back into the sampling cylinder 100.
[0025] Because the second one-way valve 107 restricts the backflow of gas from the infusion tube 103 to the subsequent pipeline, as the pressure increases, the pressure exerted by the gas on the residual liquid also increases, so that the gas can push the residual liquid out through the infusion tube 103, that is, the cerebrospinal fluid in the infusion tube 103 is transported into the sampling cylinder 100, thereby achieving the purpose of replenishing the cerebrospinal fluid in the sampling cylinder 100.
[0026] In other words, by cooperating with the piston handle 102 and the reverse thrust mechanism 120, the gas in the sampling cylinder 100 is first collected and stored in the reverse thrust mechanism 120. Then, the gas pressure in the reverse thrust mechanism 120 is used to push the remaining liquid in the infusion tube 103 back into the sampling cylinder 100, thereby filling the cerebrospinal fluid gap in the replenishment area, thereby increasing the final cerebrospinal fluid sample concentration and ensuring the accuracy of the test results.
[0027] It should be noted that, in order to prevent the cerebrospinal fluid discharged from the drain tube 130 from splashing outwards, the drain tube 130 can be guided into the cerebrospinal fluid collection tank for collection.
[0028] When testing cerebrospinal fluid, the infusion tube 103 is disconnected from the sampling tube 100, the second valve 131 is closed, and the cerebrospinal fluid in the sampling tube 100 is delivered to the detection box 110 by pushing the piston handle 102 down, so as to achieve the purpose of detecting the hydrogen sulfide content in the cerebrospinal fluid.
[0029] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The embodiments and descriptions in the specification are merely preferred examples and are not intended to limit the invention. Various changes and modifications can be made to the invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the present invention as claimed. The scope of protection of the present invention is defined by the appended claims and their equivalents.
Claims
1. A cerebrospinal fluid sampling and testing device for neurology, comprising a sampling cylinder (100), an end cap (101), a piston handle (102), and an infusion tube (103) connected to the sampling cylinder (100), wherein the end of the infusion tube (103) has a needle (104), characterized in that: A reverse thrust mechanism (120) is provided outside the sampling cylinder (100) to connect the top of the sampling cylinder (100) to the infusion tube (103). When the piston handle (102) draws in cerebrospinal fluid, the gas in the sampling cylinder (100) is pushed into the reverse thrust mechanism (120) for storage by means of the piston handle (102). When the piston handle (102) reaches the preset liquid level, a replenishment zone is formed between the preset liquid level and the cerebrospinal fluid level. The gas in the reverse thrust mechanism (120) is released to the end of the infusion tube (103) to drive the remaining liquid in the infusion tube (103) to be supplied to the sampling cylinder (100) to fill the empty cerebrospinal fluid in the replenishment zone.
2. The cerebrospinal fluid sampling and testing device for neurology according to claim 1, characterized in that: A drain pipe (130) connected to the replenishment area is provided on one side of the sampling tube (100), and a second valve (131) is provided on the drain pipe (130).
3. The neurological cerebrospinal fluid sampling and testing device according to claim 2, characterized in that: The lower edge of the drain pipe (130) at the connection point with the replenishment area is flush with the preset liquid level.
4. The neurological cerebrospinal fluid sampling and testing device according to claim 1, characterized in that: The reverse thrust mechanism (120) includes a gas collection bag (121) that is connected to the inside of the sampling cylinder (100) and used for gas collection. One end of the gas collection bag (121) is connected to the sampling cylinder (100) by a gas supply pipe (122), and the other end is connected to the end of the infusion pipe (103) by a gas supply pipe (123). A first valve (124) is provided on the gas supply pipe (123) near the gas collection bag (121).
5. The neurological cerebrospinal fluid sampling and testing device according to claim 4, characterized in that: The end cap (101) is provided with an air inlet pipe (105) that communicates with the inside of the sampling cylinder (100). Both the air inlet pipe (105) and the air supply pipe (122) are provided with a first one-way valve (125). The first one-way valve (125) located in the air supply pipe (122) is used to supply gas from the sampling cylinder (100) to the air supply pipe (122), and the first one-way valve (125) located in the air inlet pipe (105) is used to supply external gas to the sampling cylinder (100).
6. The neurological cerebrospinal fluid sampling and testing device according to claim 4, characterized in that: The infusion tube (103) is connected to an air intake manifold (106) on one side, and the air intake manifold (106) is detachably connected to the end of the air infusion tube (123).
7. The neurological cerebrospinal fluid sampling and testing device according to claim 6, characterized in that: A second one-way valve (107) is provided at the end of the infusion tube (103). The second one-way valve (107) is located in the horizontal direction below the connection between the infusion tube (103) and the air intake manifold (106), and the second one-way valve (107) is used to supply cerebrospinal fluid into the sampling tube (100).
8. The neurological cerebrospinal fluid sampling and testing device according to claim 4, characterized in that: When the gas collection bag (121) introduces gas into the infusion tube (103), it causes the pressure inside the infusion tube (103) to increase, so as to push the residual cerebrospinal fluid in the infusion tube (103) back into the sampling tube (100).