Biological material 3D printing system based on mechanical property monitoring and control method thereof

By combining acoustic radiation force optical coherence elastography technology with bio-3D printing system to monitor the mechanical properties of biomaterials in real time and dynamically adjust printing parameters, the problem of not being able to monitor and control the mechanical properties of biomaterials in real time in existing technologies is solved, thus improving the accuracy and reliability of printed products.

CN122165639APending Publication Date: 2026-06-09TIANJIN UNIVERSITY OF TECHNOLOGY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
TIANJIN UNIVERSITY OF TECHNOLOGY
Filing Date
2026-02-12
Publication Date
2026-06-09

AI Technical Summary

Technical Problem

Current bio-3D printing technology cannot monitor and regulate the mechanical properties of biomaterials in real time, resulting in a large deviation between the printed product and the mechanical properties of the target tissue.

Method used

A closed-loop control method is formed by deeply coupling acoustic radiation force optical coherent elastography technology with a bio-3D printing system. The mechanical property monitoring module acquires parameters such as elastic modulus and shear modulus in real time, and the control module dynamically adjusts the extrusion speed, crosslinking power and printing platform temperature.

Benefits of technology

This technology enables real-time monitoring and control of the mechanical properties of biomaterials during 3D printing, improving the consistency and accuracy of the mechanical properties of printed products with those of target tissues, and enhancing the reliability and clinical application value of bio-3D printing.

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Abstract

This invention relates to 3D printing, specifically providing a biomaterial 3D printing system and its control method based on mechanical property monitoring. The aim is to address the problem that existing 3D printing systems cannot monitor and regulate the mechanical properties of biomaterials in real time, leading to significant deviations between the printed product and the target tissue's mechanical properties. To this end, the control method of the 3D printing system of this invention includes the following steps: determining the biomaterial extrusion speed, crosslinking power, and 3D printing platform temperature of the 3D printing system based on the detected values ​​of the mechanical property parameters of the biomaterial printed by the 3D printing system and the threshold range of the mechanical property parameters of the target biomaterial. The control method of this invention enables closed-loop control of the mechanical properties of the printed component, significantly improving the consistency between the printed product and the target tissue's mechanical properties, improving printing accuracy and functional adaptability, and enhancing the reliability and clinical application value of biomaterial 3D printing.
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