A drug-resistant bacteria detection kit

Abstract

The application relates to the technical field of detection kits, and discloses a drug-resistant bacteria detection kit which comprises a kit body, a positioning assembly, a driving assembly, a plurality of sample tubes, a plurality of centrifugal tubes and a plurality of crushing assemblies. The positioning assembly has a limiting area for limiting the position of the sample tube or the centrifugal tube. The crushing assembly is driven by the driving assembly to rotate in the sample tube, so as to crush the sample to be ground in the sample tube. The centrifugal tube is driven by the driving assembly to rotate along the circumference of the centrifugal tube, so as to centrifuge the sample to be centrifuged in the centrifugal tube. The positioning assembly and the driving assembly are arranged in the kit body, so that the sample tube or the centrifugal tube can be limited at the preset position in the kit body, and the driving assembly can drive the crushing assembly or the centrifugal tube to rotate, so that the sample to be ground in the sample tube is crushed, and the sample to be centrifuged in the centrifugal tube is centrifuged, thereby improving the timeliness and efficiency of the detection of the drug-resistant bacteria.

Description

Technical Field

[0001] This application relates to the field of detection kit technology, and in particular to a detection kit for drug-resistant bacteria. Background Technology

[0002] Drug-resistant bacteria are a class of bacteria that exhibit significant resistance to commonly used antimicrobial drugs. Through mechanisms such as gene mutation, plasmid transfer, or acquisition of drug-resistant genes, they have evolved the ability to evade the killing or inhibition of antimicrobial drugs, easily causing refractory infections and significantly increasing the risk of treatment failure, disease prolongation, and death in patients. The infection rate is particularly high in patients in intensive care, those with immunodeficiency, those using broad-spectrum antimicrobial drugs for a long time, or those undergoing invasive treatments. This poses a serious challenge to clinical anti-infective treatment and public health prevention and control.

[0003] However, existing drug-resistant bacteria detection kits require prior disruption of solid or semi-solid samples such as sputum clots, lesion tissue, and feces to release bacteria during actual testing. Furthermore, after sample processing, nucleic acids must be separated and purified by centrifugation to remove inhibitors and impurities from the sample matrix, ensuring the accuracy of subsequent amplification reactions. However, existing kits are functionally limited, only capable of storing test reagents and disposable consumables, lacking sample disruption and centrifugation capabilities. These crucial operations must be performed using external laboratory equipment such as grinding machines and high-speed centrifuges.

[0004] This situation not only increases the complexity of the testing process, requiring multiple sample transfers between the kit and external equipment, thus increasing the risk of cross-contamination, but also limits testing operations to site and equipment conditions, making it difficult to adapt to scenarios such as primary healthcare and on-site emergency testing. Simultaneously, the scheduling of external equipment, sample transfer, and waiting time all prolong the testing cycle, significantly reducing the overall usability and efficiency of the kit, thereby adversely affecting the timeliness and efficiency of drug-resistant bacteria detection. Therefore, existing technologies require improvement and development, and a kit with sample disruption and centrifugation capabilities is lacking. Summary of the Invention

[0005] To address the shortcomings of existing technologies, this invention incorporates a positioning component and a driving component within the reagent kit. This allows the sample tube or centrifuge tube to be confined to a preset position within the kit. The driving component can then drive the crushing component or centrifuge tube to rotate, thereby crushing the sample to be ground in the sample tube and centrifuging the sample to be centrifuged in the centrifuge tube, thus improving the timeliness and efficiency of drug-resistant bacteria detection.

[0006] To solve the above-mentioned technical problems, the technical solution adopted by the present invention is as follows: a drug-resistant bacteria detection kit, comprising: a plurality of sample tubes, wherein the plurality of sample tubes are respectively separated from the kit body and are used to contain the sample to be ground; Several crushing components are arranged one-to-one in several sample tubes and are used to crush the sample to be ground in the sample tubes. Several centrifuge tubes, which are separated from the reagent kit and used to hold samples to be centrifuged; A positioning component is disposed within the receiving groove, and the positioning component has a limiting area for limiting the position of one of the sample tubes or one of the centrifuge tubes. A driving component is disposed within the receiving groove and connected to the crushing component or the centrifuge tube located within the limiting area, wherein: the crushing component is driven by the driving component to rotate within the sample tube to crush the sample to be ground inside the sample tube; The centrifuge tube is driven by the drive assembly to rotate circumferentially to centrifuge the sample to be centrifuged inside the centrifuge tube.

[0007] Furthermore, the sample tube includes: a sample tube body for containing the sample to be ground; A first spline shaft is coaxially rotatably mounted on the sample tube body and is used for detachable connection with the drive assembly. The crushing component includes: a rotating shaft, one end of which passes through the sample tube body and is coaxially connected to the first spline shaft; A crushing blade is mounted on the rotating shaft and is used to crush the sample to be ground inside the sample tube. The centrifuge tube includes: a centrifuge tube body for containing the sample to be centrifuged; The second spline shaft is coaxially fixed on the sample tube body and is used for detachable connection with the drive assembly.

[0008] Furthermore, the sample tube also includes a threaded cap, which is threadedly connected to the sample tube body and is used to close the opening of the sample tube body. The centrifuge tube further includes a sealing cap, which engages with the centrifuge tube body and is used to seal the opening of the centrifuge tube body.

[0009] Furthermore, the positioning component includes: a plurality of arc-shaped clamps, wherein the centripetal direction of the plurality of arc-shaped clamps is all directed toward the center of the limiting area; A plurality of guide slide rails are arranged facing the center of the limiting area, and a plurality of arc-shaped clamps are slidably arranged on the plurality of guide slide rails in a corresponding manner. The plurality of arc-shaped clamps are driven to have a separation state and a limiting state: in the separation state, the plurality of arc-shaped clamps are separated from each other. In the limited position state, several of the arc-shaped clamps are connected in sequence to form a ring structure, and the limited area is located within the ring structure.

[0010] Furthermore, the positioning component also includes: a plurality of magnets, which are respectively disposed at both ends of the plurality of arc-shaped clamps, and two adjacent arc-shaped clamps are detachably connected to each other through the magnets.

[0011] Furthermore, the centrifuge tube also includes an annular limiting groove, which is coaxially disposed on the outer surface of the centrifuge tube body. The annular limiting groove matches the annular structure, and the centrifuge tube body is rotatably disposed on the annular structure through the annular limiting groove.

[0012] Furthermore, the drug-resistant bacteria detection kit also includes: a fixing frame, a plurality of the guide slide rails respectively disposed on the fixing frame, the fixing frame having a limiting groove, and the driving component and the limiting area being located within the limiting groove; A fixing seat is disposed within the limiting groove and is used to support the sample tube body or centrifuge tube body.

[0013] Furthermore, the drug-resistant bacteria detection kit also includes a pull-out opening, which extends through the side of the kit body and communicates with the receiving groove; A support rail is provided, which is disposed within the receiving groove and faces the pull-out opening; A placement tray is slidably mounted on the support guide rail. The placement tray has several placement slots for placing the sample tube body or centrifuge tube body.

[0014] Furthermore, the drug-resistant bacteria detection kit also includes: a plurality of adsorption plates, which are respectively disposed at the bottom of the kit body and are used for detachable connection with the support surface.

[0015] Furthermore, the kit includes: a kit body; An easy-tear opening is provided on the reagent kit body and communicates with the limiting area; Side support plate, the side support plate covering the easy-tear opening.

[0016] Beneficial effects: By setting a positioning component and a driving component within the kit, the present invention can restrict the sample tube or centrifuge tube to a preset position within the kit. The driving component can drive the crushing component or centrifuge tube to rotate, thereby crushing the sample to be ground in the sample tube and centrifuging the sample to be centrifuged in the centrifuge tube, thus improving the timeliness and efficiency of drug-resistant bacteria detection. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the structure of the drug-resistant bacteria detection kit (in isolation state) provided by the present invention; Figure 2 This is a schematic diagram of the structure of the drug-resistant bacteria detection kit (limited state) provided by the present invention; Figure 3 A cross-sectional view of the drug-resistant bacteria detection kit provided by the present invention; Figure 4 An exploded view of the structure of the drug-resistant bacteria detection kit provided by this invention; Figure 5 A schematic diagram of the structure of the drug-resistant bacteria detection kit provided by the present invention from another perspective; Figure 6 This is a schematic diagram of the structure of the drug-resistant bacteria detection kit provided by the present invention from another perspective. Figure 7 This is a schematic diagram of the structure of the drug-resistant bacteria detection kit provided by the present invention; Figure 8 This is a schematic diagram of the positioning component provided by the present invention; Figure 9 A cross-sectional view of the sample tube provided by the present invention; Figure 10 This is a schematic diagram of the structure of the centrifuge tube provided by the present invention.

[0018] The labels in the attached diagram are as follows: 100, reagent kit body; 110, reagent kit body; 111, receiving slot; 112, easy-tear opening; 113, pull-out opening; 120, side support plate; 130, suction plate; 200, sample tube; 210, sample tube body; 220, first spline shaft; 230, crushing assembly; 231, rotating shaft; 232, crushing blade; 240, threaded cap; 300, centrifuge tube; 310, centrifuge tube body; 311, annular limiting groove; 320, second spline shaft; 330, sealing cap; 400, positioning assembly; 410, arc-shaped clamp; 411, limiting area; 420, guide rail; 430, magnet; 500, drive assembly; 600, fixing frame; 610, limiting groove; 620, fixing base; 700, placement tray; 710, placement groove; 720, support guide rail. Detailed Implementation

[0019] This invention provides a drug-resistant bacteria detection kit. To make the objectives, technical solutions, and effects of this invention clearer and more explicit, the invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only for explaining the invention and are not intended to limit the invention.

[0020] It should be noted that when a component is referred to as being "fixed to" or "set on" another component, it can be directly on or indirectly on that other component. When a component is referred to as being "connected to" another component, it can be directly connected to or indirectly connected to that other component.

[0021] It should also be noted that the same or similar reference numerals in the accompanying drawings of the embodiments of the present invention correspond to the same or similar components; in the description of the present invention, it should be understood that if terms such as "upper," "lower," "left," "right," etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, they are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, the terms used to describe positional relationships in the accompanying drawings are only for illustrative purposes and should not be construed as limiting the present patent. For those skilled in the art, the specific meaning of the above terms can be understood according to the specific circumstances.

[0022] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly specified.

[0023] The invention will be further explained below with reference to the accompanying drawings and the description of the embodiments.

[0024] This embodiment provides a drug-resistant bacteria detection kit, such as Figures 1 to 10 As shown, to solve the above-mentioned technical problems, the technical solution adopted by the present invention is as follows: It includes a reagent kit 100, a positioning component 400, a driving component 500, a plurality of sample tubes 200, a plurality of crushing components 230, and a plurality of centrifuge tubes 300. The plurality of sample tubes 200 are separated from the reagent kit 100 and used to contain samples to be ground, and the plurality of centrifuge tubes 300 are separated from the reagent kit 100 and used to contain samples to be centrifuged. The plurality of crushing components 230 are correspondingly arranged in the plurality of sample tubes 200 and are used to crush the samples to be ground in the sample tubes 200. The reagent kit 100 has a receiving groove 111, and the positioning component 400 and the driving component 500 are respectively disposed in the receiving groove 111. The positioning component 400 has a limiting area 411, which is used to limit the position of one of the sample tubes 200 or one of the centrifuge tubes 300. The driving component 500 is connected to the crushing component 230 or the centrifuge tube 300 located in the limiting area 411.

[0025] In practical use, the operator first places the reagent kit 100 on the table and then determines the type of sample. If the sample is a solid or semi-solid sample (such as sputum clots or tissue blocks), the sample is placed in the sample tube 200, which is then placed in the limiting area 411 and positioned by the positioning component 400. Next, the driving component 500 drives the crushing component 230 inside the sample tube 200 to crush the sample to be ground. If the sample requires centrifugation purification, the sample is injected into the centrifuge tube 300, which is then placed in the limiting area 411 and positioned by the positioning component 400. Next, the driving component 500 drives the centrifuge tube 300 to rotate, centrifuging the sample inside. Preferably, the reagent kit 100 has a top cover on its upper surface. In the packaged state, the top cover closes the receiving slot 111, allowing each component to be stored within it.

[0026] Existing drug-resistant bacteria detection kits require prior disruption of solid or semi-solid samples such as sputum clots, lesion tissue, and feces to release bacteria. Following sample processing, nucleic acids must be purified by centrifugation to remove inhibitors and impurities from the sample matrix, ensuring the accuracy of subsequent amplification reactions. However, existing kits are functionally limited, only capable of storing reagents and disposable consumables, lacking sample disruption and centrifugation capabilities. These critical operations rely on external instruments such as laboratory-specific grinding equipment and high-speed centrifuges. This not only increases the complexity of the testing process, requiring multiple sample transfers between the kit and external equipment, increasing the risk of cross-contamination, but also limits the testing operation to site and equipment limitations, making it unsuitable for scenarios such as primary healthcare and on-site emergency testing. Furthermore, the scheduling of external equipment, sample transfer, and waiting time all prolong the testing cycle, significantly reducing the overall practicality and efficiency of the kits, thus negatively impacting the timeliness and efficiency of drug-resistant bacteria detection.

[0027] This invention integrates the sample crushing and centrifugation functions into a single design by combining the drive component 500 and the crushing component 230. This eliminates the need for external grinding equipment and high-speed centrifuges, saving time on scheduling and waiting for external equipment, reducing the number of times samples are transferred between the reagent kit and external equipment, and reducing the chance of samples being exposed to the external environment. This reduces the risk of cross-contamination and improves detection efficiency compared to existing technologies.

[0028] In one embodiment, such as Figure 3 , Figure 9 , Figure 10As shown, the sample tube 200 includes a sample tube body 210 and a first splined shaft 220, and the crushing assembly 230 includes a rotating shaft 231 and a crushing blade 232. The sample tube body 210 is used to contain the sample to be ground. One end of the rotating shaft 231 passes through the lower end of the sample tube body 210 and is coaxially connected to the first splined shaft 220, and the rotating shaft 231 is rotatably and sealed to the sample tube body. The crushing blade 232 is disposed on the rotating shaft 231, and when the rotating shaft 231 rotates, the crushing blade 232 can crush the sample to be ground in the sample tube body 210. The centrifuge tube 300 includes a centrifuge tube body 310 and a second splined shaft 320. The centrifuge tube body 310 is used to contain the sample to be centrifuged, and the second splined shaft 320 is coaxially and fixedly disposed on the sample tube body 210.

[0029] In one embodiment, such as Figures 1 to 4 , Figures 6 to 7 As shown, the drug-resistant bacteria detection kit also includes: a mounting frame 600 and a mounting base 620. Several guide rails 420 are respectively mounted on the mounting frame 600. The mounting frame 600 is cylindrical and has an internal limiting groove 610. The drive assembly 500 and the limiting area 411 are both located within the limiting groove 610. Specifically, as... Figure 3 As shown, the drive assembly 500 includes a motor and a spline sleeve. The output shaft of the motor is axially arranged upwards, passes through the fixed seat 620, and is connected to the spline sleeve. Both the first spline shaft 220 and the second spline shaft 320 are detachably connected to the spline sleeve. Both the first spline shaft 220 and the second spline shaft 320 are connected to the motor via the spline sleeve, allowing them to rotate under the motor's drive. The fixed seat 620 is disposed within the limiting groove 610. The top surface of the fixed seat 620 is recessed to form a recessed portion, within which the spline sleeve is disposed. This recessed portion supports and limits the bottom end of the sample tube body 210 or the centrifuge tube body 310, preventing the sample tube body 210 or the centrifuge tube body 310 from tipping over, in conjunction with the positioning assembly 400. Preferably, both the first spline shaft 220 and the second spline shaft 320 are externally hexagonal.

[0030] In one embodiment, such as Figure 3 , Figure 9 , Figure 10 As shown, sample tube 200 also includes a threaded cap 240, which is threadedly connected to sample tube body 210 and used to seal the opening of sample tube body 210; centrifuge tube 300 also includes a sealing cap 330, which is snapped into centrifuge tube body 310 and used to seal the opening of centrifuge tube body 310. In actual use, after the operator puts the sample into sample tube body 210, tightening the threaded cap 240 achieves a seal to prevent the sample from splashing out of sample tube body 210 during the breakage process; after injecting the sample into centrifuge tube 300, the sealing cap 330 is tightly closed on centrifuge tube body 310 to prevent leakage during centrifugation.

[0031] In one embodiment, such as Figures 1 to 4 , Figures 6 to 8 As shown, the positioning component 400 includes two arc-shaped clamping plates 410 and two guide rails 420. The two guide rails 420 are arranged in the same direction, and the two arc-shaped clamping plates 410 are both semi-circular. The two arc-shaped clamping plates 410 can move in the same direction or in opposite directions through the two guide rails 420. In actual use, the operator can move the two arc-shaped clamping plates 410 by hand, so that the two arc-shaped clamping plates 410 separate from each other or come into contact with each other to form a ring structure. The limiting area 411 is located within the ring structure. The sample tube body 210 can be clamped and fixed by the ring structure, and the centrifuge tube body 310 can be limited by the ring structure and thus rotate within the ring structure.

[0032] In one embodiment, such as Figure 8 As shown, the positioning assembly 400 further includes four magnets 430, which are respectively disposed at both ends of the two arc-shaped clamps 410 in the circumferential direction. The two arc-shaped clamps 410 are detachably connected to each other through the magnets 430 at both ends to form a ring structure.

[0033] In practical use, the operator needs to check the status of the positioning clamps before use. Push the positioning clamps by hand to ensure they slide smoothly on the guide slider. When the two positioning clamps come close together, they should be able to magnetically attract and separate. Next, the operator separates the two positioning clamps and places the sample tube 200 or centrifuge tube 300 between them, engaging the first spline shaft 220 or the second spline shaft 320 with the spline sleeve. Then, push the two positioning clamps with both hands, allowing the bottom ends of the clamps to slide along the guide rail 420. When the two positioning clamps approach each other to a preset position, they are attracted and fixed together by the magnet 430, forming a stable ring structure. The inner wall of the positioning clamps can tightly fit the outer wall of the sample tube body 210 or have a clearance fit with the centrifuge tube body 310, preventing radial wobbling of the sample tube body 210 and centrifuge tube body 310 during high-speed motor rotation. Subsequently, the operator starts the motor to perform sample crushing or centrifugation. The vibration generated by the motor is transmitted to the tabletop through the fixing bracket 600, while the sample tube body 210 and centrifuge tube body 310 are effectively kept stable by the positioning clamps and the fixing base 620. After the operation is completed, the operator pushes the two positioning clamps in opposite directions with both hands to separate them. At this time, the two positioning clamps return to their original position along the guide rail 420, and then the sample tube body 210 or centrifuge tube body 310 can be removed. If other samples need to be processed, the above positioning steps can be repeated. The entire process requires no additional tools and is convenient and efficient.

[0034] This invention utilizes a magnetic fixing structure for the positioning clamp, combined with the precise engagement of the spline sleeve and spline shaft. The magnetic attraction of the clamp allows it to fit tightly against the outer wall of the test tube. The cooperation between the guide groove and the guide slider ensures smooth movement of the clamp and higher positioning accuracy. At the same time, the tight fit of the spline structure prevents slippage during rotation. This dual protection ensures that the sample tube 200 and centrifuge tube 300 remain stable during high-speed crushing and centrifugation, effectively preventing test tube tipping or sample leakage, and improving the safety and reliability of the testing operation.

[0035] In one embodiment, such as Figure 10 As shown, the centrifuge tube 300 also includes an annular limiting groove 311, which is coaxially disposed on the outer surface of the centrifuge tube body 310. The annular structure is clearance-fitted with the centrifuge tube body 310 through the annular limiting groove 311. Preferably, the inner diameter of the annular structure is smaller than the outer diameter of the centrifuge tube body 310 and larger than the outer diameter of the annular limiting groove 311, thereby restricting the axial and radial degrees of freedom of the centrifuge tube body 310, allowing the centrifuge tube body 310 to be rotatably mounted on the annular structure, and improving the stability of the centrifuge tube body 310 during centrifugation.

[0036] In one embodiment, such as Figures 1 to 7 As shown, the drug-resistant bacteria detection kit also includes: a pull-out opening 113, a support rail 720, and a placement tray 700. The pull-out opening 113 extends through the side of the kit body 100 and communicates with the receiving groove 111. The support rail 720 is disposed within the receiving groove 111 and faces the pull-out opening 113. The placement tray 700 is slidably disposed on the support rail 720 and has several placement slots 710 for placing sample tube bodies 210 or centrifuge tube bodies 310. Preferably, sliding protrusions are symmetrically fixed to the lower edge of the placement tray 700, and the sliding protrusions are slidably connected to the support rail 720. One end of the placement tray 700 has an clearance notch that matches the fixing frame 600, so that the placement tray 700 and other components can be located within the receiving groove 111 and housed by the kit body 100.

[0037] In practical use, when the sample needs to be placed in the dark, the operator can hold one end of the placement tray 700 on the pull-out port 113 and slowly pull it outward. The sliding protrusion on the bottom surface of the placement tray 700 slides along the support guide rail 720 on the inner wall of the reagent kit 100 until the placement slot 710 is fully exposed. Next, the operator places the sample tubes 200 or centrifuge tubes 300 that need to stand into the placement slots 710 on the upper surface of the placement tray 700 one by one. The size of the placement slots 710 is precisely matched with the outer wall of the test tubes, ensuring that the test tubes are placed vertically, stably and without shaking, and can accommodate multiple sets of samples at the same time to meet the needs of batch processing. Finally, the operator pushes the placement tray 700 back into the reagent kit 100 along the support rails 720. The clearance notch on the placement tray 700 just avoids the fixing frame 600 and is perfectly matched with the internal space of the reagent kit 100 without interference. Then the top cover is closed. The light-shielding layer on the inner wall of the top cover effectively blocks the entry of external light, providing a sealed light-proof environment for the samples and avoiding the influence of light on the activity of the samples. After the standing period is completed, the operator pulls out the placement tray 700 again, takes out the sample tubes 200 or centrifuge tubes 300 for subsequent testing, and pushes the placement tray 700 back into place and closes the top cover.

[0038] This invention utilizes a pull-out light-proof storage component. Multiple placement slots 710 on the placement tray 700 can simultaneously accommodate multiple sets of sample tubes 200 and centrifuge tubes 300, facilitating the static processing of batch samples without the need for additional light-proof containers. The light-shielding layer on the inner wall of the top cover effectively blocks external light interference, meeting the static requirements of light-sensitive samples, ensuring sample activity and the accuracy of subsequent test results, and further expanding the functionality and practicality of the reagent kit.

[0039] In one embodiment, such as Figure 5 As shown, the reagent kit 100 includes: a reagent kit body 110, an easy-tear opening 112, and several suction trays 130. The easy-tear opening 112 is disposed on the reagent kit body 110 and communicates with the limiting area 411. A side support plate 120 covers the easy-tear opening 112. Several suction trays 130 are respectively disposed at the bottom of the reagent kit 100 and are used for detachable connection with the support surface.

[0040] Preferably, the reagent kit 110 has an integrally formed support base on its bottom surface. The support base can be a plastic plate or a metal plate and is relatively flat. Adsorption trays 130 are provided near the four corners of the bottom surface of the support base, allowing the operator to adhere the reagent kit 110 to the tabletop. The easy-tear opening 112 on the reagent kit 100 is closed by a side support plate 120, which is connected to the reagent kit 110 by an easy-tear line, facilitating the operator to tear open and expose the components inside the receiving slot 111.

[0041] This invention utilizes the cooperation between the support base and the adsorption plate 130. The strong adsorption force of the adsorption plate 130 can adapt to tabletops with varying flatness, ensuring the stability of the reagent kit 100 even during high-vibration operations such as crushing and centrifugation. Combined with the easy-tear seam and easy-tear strip design of the side support plate 120, the reagent kit can be quickly opened without the need for tools, simplifying the operation process and making it suitable for scenarios lacking professional laboratory conditions, such as primary healthcare and on-site emergency testing, significantly improving the versatility of the reagent kit.

[0042] In summary, this application relates to the field of detection kit technology and discloses a drug-resistant bacteria detection kit, which includes a kit body, a positioning component, a driving component, several sample tubes, several centrifuge tubes, and several crushing components. The positioning component has a limiting area for restricting the position of the sample tubes or centrifuge tubes. The crushing components are driven by the driving component to rotate within the sample tubes to crush the samples to be ground inside the sample tubes. The centrifuge tubes are driven by the driving component to rotate circumferentially to centrifuge the samples to be centrifuged inside the centrifuge tubes. This invention, by setting a positioning component and a driving component within the kit body, can restrict the sample tubes or centrifuge tubes to a preset position within the kit body, and can drive the crushing components or centrifuge tubes to rotate via the driving component, thereby crushing the samples to be ground in the sample tubes and centrifuging the samples to be centrifuged in the centrifuge tubes, improving the timeliness and efficiency of drug-resistant bacteria detection.

[0043] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A reagent kit for detecting drug-resistant bacteria, comprising a kit body having a receiving slot, characterized in that, The drug-resistant bacteria detection kit includes: several sample tubes, each of which is separated from the kit body and used to contain the sample to be ground; Several crushing components are arranged one-to-one in several sample tubes and are used to crush the sample to be ground in the sample tubes. Several centrifuge tubes, which are separated from the reagent kit and used to hold samples to be centrifuged; A positioning component is disposed within the receiving groove, and the positioning component has a limiting area for limiting the position of one of the sample tubes or one of the centrifuge tubes. A driving component is disposed within the receiving groove and connected to the crushing component or the centrifuge tube located within the limiting area, wherein: the crushing component is driven by the driving component to rotate within the sample tube to crush the sample to be ground inside the sample tube; The centrifuge tube is driven by the drive assembly to rotate circumferentially to centrifuge the sample to be centrifuged inside the centrifuge tube.

2. The drug-resistant bacteria detection kit according to claim 1, characterized in that, The sample tube includes: a sample tube body for containing the sample to be ground; A first spline shaft is coaxially rotatably mounted on the sample tube body and is used for detachable connection with the drive assembly. The crushing component includes: a rotating shaft, one end of which passes through the sample tube body and is coaxially connected to the first spline shaft; A crushing blade is mounted on the rotating shaft and is used to crush the sample to be ground inside the sample tube. The centrifuge tube includes: a centrifuge tube body for containing the sample to be centrifuged; The second spline shaft is coaxially fixed on the sample tube body and is used for detachable connection with the drive assembly.

3. The drug-resistant bacteria detection kit according to claim 2, characterized in that, The sample tube further includes a threaded cap, which is threadedly connected to the sample tube body and is used to close the opening of the sample tube body. The centrifuge tube further includes a sealing cap, which engages with the centrifuge tube body and is used to seal the opening of the centrifuge tube body.

4. The drug-resistant bacteria detection kit according to claim 2, characterized in that, The positioning component includes: a plurality of arc-shaped clamps, wherein the centripetal direction of the plurality of arc-shaped clamps is all toward the center of the limiting area; A plurality of guide slide rails are arranged facing the center of the limiting area, and a plurality of arc-shaped clamps are slidably arranged on the plurality of guide slide rails in a corresponding manner. The plurality of arc-shaped clamps are driven to have a separation state and a limiting state: in the separation state, the plurality of arc-shaped clamps are separated from each other. In the limited position state, several of the arc-shaped clamps are connected in sequence to form a ring structure, and the limited area is located within the ring structure.

5. The drug-resistant bacteria detection kit according to claim 4, characterized in that, The positioning component further includes: a plurality of magnets, which are respectively disposed at both ends of the plurality of arc-shaped clamps, and two adjacent arc-shaped clamps are detachably connected to each other through the magnets.

6. The drug-resistant bacteria detection kit according to claim 4, characterized in that, The centrifuge tube further includes an annular limiting groove, which is coaxially disposed on the outer surface of the centrifuge tube body. The annular limiting groove matches the annular structure, and the centrifuge tube body is rotatably disposed on the annular structure through the annular limiting groove.

7. The drug-resistant bacteria detection kit according to claim 4, characterized in that, The drug-resistant bacteria detection kit further includes: a fixed frame, a plurality of guide rails respectively disposed on the fixed frame, the fixed frame having a limiting groove, and the driving component and the limiting area both located within the limiting groove; A fixing seat is disposed within the limiting groove and is used to support the sample tube body or centrifuge tube body.

8. The drug-resistant bacteria detection kit according to claim 2, characterized in that, The drug-resistant bacteria detection kit further includes: a pull-out opening, which is disposed through the side of the kit body and communicates with the receiving groove; A support rail is provided, which is disposed within the receiving groove and faces the pull-out opening; A placement tray is slidably mounted on the support guide rail. The placement tray has several placement slots for placing the sample tube body or centrifuge tube body.

9. The drug-resistant bacteria detection kit according to claim 1, characterized in that, The drug-resistant bacteria detection kit further includes: several adsorption plates, which are respectively disposed at the bottom of the kit body and are used for detachable connection with the support surface.

10. The drug-resistant bacteria detection kit according to claim 1, characterized in that, The kit includes: the kit body; An easy-tear opening is provided on the reagent kit body and communicates with the limiting area; Side support plate, the side support plate covering the easy-tear opening.

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