A skin-protecting composition containing natural antioxidant active substances and a process for its production

Abstract

This invention discloses a skin protection composition containing natural antioxidant active substances and its preparation method, relating to the field of daily chemical products technology. The composition includes natural antioxidant active components, an oil phase, an aqueous phase, a moisturizing component, a thickening and stabilizing component, and auxiliary components. This invention enhances skin protection by using maqui berry extract as the core antioxidant ingredient and sea buckthorn flavonoid extract. By employing elderberry extract as an antioxidant compound ingredient, it complements maqui berry extract and sea buckthorn flavonoids, creating a multi-target synergistic effect in the antioxidant mechanism. This constructs a multi-target synergistic antioxidant defense network, achieving complementary and synergistic effects in the mechanism of action. It blocks the oxidation chain reaction at multiple stages, and the compounding of various natural antioxidant active substances provides more comprehensive and longer-lasting protection for the skin from oxidative damage, achieving highly effective skin protection.

Description

Technical Field

[0001] This invention relates to the field of daily chemical products technology, specifically to a skin protection composition containing natural antioxidant active substances and its preparation method. Background Technology

[0002] As the largest organ in the human body, the skin is directly exposed to the external environment and is deeply affected by factors such as ultraviolet radiation, air pollution, and oxidative stress. These environmental factors can induce the production of a large number of reactive oxygen species (ROS), leading to oxidative damage to the skin, manifested as dryness, sagging, wrinkles, and pigmentation. In severe cases, it may even induce skin tumors. Oxidative stress is one of the fundamental mechanisms of skin aging. Antioxidants have important application value in the field of skin protection. Modern skin care is shifting from single-function to multi-target synergy, especially emphasizing the maintenance of barrier health and microecological balance while scavenging free radicals (antioxidants). Natural antioxidants, due to their high safety and few side effects, have become an important direction for replacing chemical antioxidants (such as BHT and BHA). In the prior art, Chinese patent application number 202411841701.8, entitled "Composition for Skin Protection Containing Thymol Ester Compounds", discloses that the composition increases the expression of DNA repair-related genes in skin cells that are photoaged by ultraviolet radiation, thereby inhibiting or preventing skin damage caused by ultraviolet radiation, external environment, or oxidative stress.

[0003] Current antioxidant skin protection products mainly use synthetic antioxidants or single natural antioxidant ingredients. Although synthetic antioxidants perform well in terms of antioxidant efficiency, they have potential safety issues. Synthetic substances can also have adverse effects on human cells. Single natural antioxidant ingredients are safe, but their antioxidant effect is low and they cannot cope with complex application environments. Summary of the Invention

[0004] This invention provides a skin protection composition containing natural antioxidant active substances and its preparation method, which can effectively solve the problems mentioned in the background art that current antioxidant skin protection products mainly use synthetic antioxidants or single natural antioxidant ingredients. Although synthetic antioxidants perform well in terms of antioxidant efficiency, they have potential safety issues and synthetic substances can also have adverse effects on human cells. Although single natural antioxidant ingredients have high safety, their antioxidant effect is low and they cannot cope with complex application environments.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a skin protection composition containing natural antioxidant active substances, comprising natural antioxidant active components, oil phase components, aqueous phase components, moisturizing components, thickening and stabilizing components, and auxiliary components; The natural antioxidant active ingredients consist of maquillia fruit extract, sea buckthorn flavonoid extract and elderberry extract; The oil phase component consists of caprylic / capric triglyceride, tocopheryl acetate, avocado oil, shea butter, and polydimethylsiloxane, and the aqueous phase component consists of deionized water, butanediol, and glycerol. The moisturizing component consists of panthenol, purslane extract and β-glucan; the thickening and stabilizing component consists of hydroxyethyl cellulose, carbomer 940, xanthan gum, cetearyl oleate and cetearyl alcohol; and the auxiliary component consists of phenoxyethanol, ethylhexylglycerin, arginine and disodium EDTA.

[0006] According to the above technical solution, the total content of the natural antioxidant active ingredients is 3.5-12.0%, the total content of the oil phase ingredients is 10.0-32.0%, the total content of the aqueous phase ingredients is 42.0-74.0%, the total content of the moisturizing ingredients is 1.2-8.4%, the total content of the thickening and stabilizing ingredients is 2.0-7.1%, and the total content of the auxiliary ingredients is 0.1-1.2%.

[0007] According to the above technical solution, the weight percentages of each component in the natural antioxidant active ingredient composition are as follows: Maquillia fruit extract 0.8-4.4%, sea buckthorn flavonoid extract 1.1-3.6%, elderberry extract 1.2-5.0%; The weight percentages of each composition within the oil phase are as follows: Caprylic / capric triglycerides 2.1-12.0%, tocopheryl acetate 0.5-3.0%, avocado oil 2.2-6.8%, shea butter 1.2-5.3%, polydimethylsiloxane 0.5-6.4%; The weight percentages of each composition within the aqueous phase are as follows: Deionized water 34.0-72.0%, butanediol 2.0-11.0%, glycerol 1.2-7.0%.

[0008] According to the above technical solution, the weight percentages of each component in the moisturizing component are as follows: Panthenol 0.5-3.0%, Portulaca oleracea extract 0.6-4.2%, β-glucan 0.2-1.5%; The weight percentages of each component in the thickening and stabilizing component are as follows: Hydroxyethyl cellulose 0.1-1.2%, Carbomer 940 0.2-1.3%, Xanthan gum 0.1-0.9%, Cetearyl alcohol oleate 0.2-2.2%, Cetearyl alcohol 0.05-1.3%; The weight percentages of each composition within the auxiliary components are as follows: Phenoxyethanol 0.01-0.65%, ethylhexylglycerin 0.01-0.3%, arginine 0.01-0.5%, disodium ethylenediaminetetraacetate 0.01-0.06%.

[0009] According to the above technical solution, the octanoic acid / capric acid triglyceride in the oil phase component is a light oil formed by esterification of octanoic acid and capric acid with glycerol, the tocopheryl acetate is vitamin E acetate, the avocado oil is a plant oil extracted from avocado fruit, the shea butter is a plant oil extracted from shea fruit, and the polydimethylsiloxane is a silicone oil raw material with low viscosity characteristics. Panthenol in the moisturizing and soothing components is an alcohol derivative of vitamin B5, and β-glucan is a polysaccharide extracted from oats or yeast. The hydroxyethyl cellulose in the thickening and stabilizing components is a water-soluble cellulose ether thickener, and carbomer 940 is a polyacrylic acid crosslinking polymer, which is widely used in cosmetics as a gel matrix and thickener. Xanthan gum is a microbial polysaccharide produced by Xanthomonas fermentation. Cetearyl alcohol olive oil ester is a plant-derived emulsifier and skin conditioner, which is formed by esterification of olive oil fatty acids and cetearyl alcohol. Cetearyl alcohol is a fatty alcohol composed of cetyl alcohol and stearyl alcohol.

[0010] A method for preparing a skin protection composition containing natural antioxidant active substances includes the following preparation process: Step S1, Raw material preparation and inspection; Step S2, aqueous phase preparation; Step S3, oil phase preparation; Step S4, two-step emulsification operation; Step S5, gradient cooling process; Step S6: Post-processing and quality inspection.

[0011] According to the above technical solution, in step S1, all raw materials used are subjected to quality inspection and pretreatment, including testing the content of active ingredients, heavy metal residues, pesticide residues, and microbial limits of each raw material. After the inspection, the raw materials are weighed according to the formula dosage. Solid raw materials, liquid raw materials, and aqueous raw materials are classified and stored separately in labeled sealed containers for later use. At the same time, natural antioxidant active substances are stored in glass containers in a dark and low-temperature environment.

[0012] According to the above technical solution, in step S2, deionized water is first added to a stainless steel preparation tank and stirring is started. Then, butanediol and glycerin are added to the deionized water and stirring is continued to make the moisturizer fully dissolved and mixed evenly with the deionized water. After complete dissolution, the pre-sieved hydroxyethyl cellulose powder is added to the aqueous phase. The hydroxyethyl cellulose powder is added gradually while stirring. After all the powder is added, it is stirred to form a uniform viscous liquid. Then, carbomer 940 powder is added uniformly to the aqueous phase while stirring. After all the carbomer is added, it is stirred to allow the carbomer to fully swell and form a transparent gel system. Xanthan gum powder and butylene glycol were premixed to prepare a xanthan gum predispersant solution, which was then slowly added to the aqueous phase while stirring. After all the xanthan gum was added, the mixture was stirred until homogeneous. Panthenol and β-glucan were dissolved in deionized water and slowly added to the aqueous phase system. After stirring until homogeneous, purslane extract was added to the aqueous phase and stirring was continued. Arginine was dissolved in deionized water to prepare an arginine solution, which was then slowly added dropwise to the aqueous phase system. The pH value was monitored and adjusted, and the mixture was stirred until homogeneous. Finally, dissolve disodium ethylenediaminetetraacetate in deionized water and add it to the aqueous phase system. Stir and mix well. After the aqueous phase preparation is completed, adjust the temperature of the aqueous phase tank to 70-75℃ and keep it warm. In step S3, all oil phase raw materials are added to a stainless steel oil phase preparation tank, and the heating and stirring mechanism is started to heat the oil phase mixture to 75-80°C. During the heating process, stirring is continued. After the oil phase mixture is heated to 75-80°C, stirring and heat preservation are continued for 15 minutes.

[0013] According to the above technical solution, in step S4, the emulsification operation is carried out while the oil phase is hot after the oil phase preparation is completed. First, the aqueous phase mixture and the oil phase mixture at 75-80℃ are filtered through a filter device. The filtered oil phase is slowly injected into the aqueous phase by a fine droplet method, while stirring is started. After the oil phase is injected, the shear stirring state is maintained, and the emulsification time is not less than 10 minutes. Then, after emulsification, high-pressure homogenization is performed. The obtained emulsion is transferred to a high-pressure homogenizer for circulating homogenization. The number of cycles is 3, and the cycle time is 5 minutes each time. After homogenization is completed, samples are taken for testing.

[0014] According to the above technical solution, in step S5, after emulsification is completed, the product is cooled to below room temperature. The emulsification tank is first switched to cooling circulation mode, and the cooling rate is controlled to decrease by 0.5-1.0℃ per minute. During the cooling process, low-speed stirring is maintained. When the temperature is cooled to 50-55℃, phenoxyethanol and ethylhexylglycerin are premixed evenly and then slowly added to the cooling emulsion system. Stirring is continued for 15 minutes to ensure that the preservative is fully dispersed. When the temperature continues to cool to 40-45℃, the extracts of Maquillicium erinaceus, Hippophae rhamnoides and Elderberry are pre-diluted with butylene glycol and then slowly added to the emulsion system in sequence. After each extract is added, the mixture is stirred for 5 minutes. After the mixture is fully dispersed, the next extract is added. After the last extract is added, the mixture is stirred again. Continue cooling until the product is cooled to room temperature; In step S6, after gradient cooling is completed, the product is transferred to a vacuum degassing tank and degassed under a vacuum of -0.08 to -0.09 MPa to remove air bubbles trapped in the product. After degassing, quality inspection is carried out. The inspection items include: appearance, pH value, viscosity, microbial limit and stability. For products containing natural antioxidant active substances, accelerated stability test is also required. After the product quality inspection is passed, it is filled by an automatic cream filling machine, using light-proof plastic bottles with sealed inner caps as packaging containers, and sealed immediately after filling.

[0015] Compared with the prior art, the beneficial effects of the present invention are as follows: 1. By using maqui berry extract as the core antioxidant ingredient, which has high antioxidant capacity, and sea buckthorn flavonoid extract, which has a strong free radical scavenging ability and has a significant scavenging effect on various reactive oxygen species, the product enhances the skin protection effect. By using elderberry extract as an antioxidant compound ingredient, it complements maqui berry extract and sea buckthorn flavonoids to form a multi-target synergistic effect in the antioxidant mechanism, which can more comprehensively and effectively protect the skin from oxidative damage. By scientifically combining maquilli fruit extract, sea buckthorn flavonoid extract, and elderberry extract, a multi-target synergistic antioxidant defense network is constructed. The mechanisms of action are complementary and synergistic, blocking the oxidation chain reaction at multiple stages. The combination of various natural antioxidant active substances can more comprehensively and longer protect the skin from oxidative damage, achieving highly effective skin protection.

[0016] 2. By using an oil-in-water emulsion system to prepare the skin protection composition, the safety and quality stability of the product are ensured. Furthermore, through a specific thickening system and emulsification process, the stability of the active ingredients in the product and the skin penetration rate are ensured. This effectively protects the anthocyanins in the maqui berry extract from oxidative degradation and extends the effective use period of the product. Attached Figure Description

[0017] The accompanying drawings are provided to further illustrate the invention and form part of the specification. They are used together with the embodiments of the invention to explain the invention and do not constitute a limitation thereof.

[0018] In the attached diagram: Figure 1 This is a flowchart of the steps in the preparation method of the skin protection composition of the present invention. Detailed Implementation

[0019] The preferred embodiments of the present invention will be described below with reference to the accompanying drawings. It should be understood that the preferred embodiments described herein are for illustration and explanation only and are not intended to limit the present invention.

[0020] Example 1: This invention provides a technical solution: a skin protection composition containing natural antioxidant active substances, comprising natural antioxidant active components, oil phase components, aqueous phase components, moisturizing components, thickening and stabilizing components, and auxiliary components. The natural antioxidant active ingredients consist of maquillia fruit extract, sea buckthorn flavonoid extract and elderberry extract; The oil phase consists of caprylic / capric triglycerides, tocopheryl acetate, avocado oil, shea butter, and polydimethylsiloxane, while the aqueous phase consists of deionized water, butanediol, and glycerol. The moisturizing components consist of panthenol, purslane extract, and β-glucan; the thickening and stabilizing components consist of hydroxyethyl cellulose, carbomer 940, xanthan gum, cetearyl oleate, and cetearyl alcohol; and the auxiliary components consist of phenoxyethanol, ethylhexylglycerin, arginine, and disodium EDTA-2Na.

[0021] Based on the above technical solution, the total content of natural antioxidant active ingredients is 8.5%, the total content of oil phase ingredients is 18.0%, the total content of aqueous phase ingredients is 65.0%, the total content of moisturizing ingredients is 4.5%, the total content of thickening and stabilizing ingredients is 3.5%, and the total content of auxiliary ingredients is 0.5%.

[0022] Based on the above technical solution, the weight percentages of each component in the natural antioxidant active ingredient composition are as follows: Maquillia fruit extract 3.0%, sea buckthorn flavonoid extract 2.5%, elderberry extract 3.0%; The weight percentages of each component in the oil phase are as follows: Caprylic / capric triglycerides 6.0%, tocopheryl acetate 1.5%, avocado oil 4.5%, shea butter 3.0%, polydimethylsiloxane 3.0%; The weight percentages of each component in the aqueous phase are as follows: Deionized water 55.0%, butylene glycol 5.0%, glycerin 5.0%.

[0023] Based on the above technical solution, the weight percentages of each component in the moisturizing part are as follows: Panthenol 2.0%, Portulaca oleracea extract 1.5%, β-glucan 1.0%; The weight percentages of each component in the thickening and stabilizing components are as follows: Hydroxyethyl cellulose 0.8%, Carbomer 940 0.5%, Xanthan gum 0.5%, Cetearyl alcohol oleate 1.0%, Cetearyl alcohol 0.7%; The weight percentages of each component in the auxiliary components are as follows: Phenoxyethanol 0.25%, ethylhexylglycerol 0.15%, arginine 0.08%, disodium ethylenediaminetetraacetate 0.02%.

[0024] Based on the above technical solution, the octanoic acid / capric acid triglyceride in the oil phase is a light oil formed by esterification of octanoic acid and capric acid with glycerol, the tocopheryl acetate is vitamin E acetate, the avocado oil is a plant oil extracted from avocado fruit, the shea butter is a plant oil extracted from shea fruit, and the polydimethylsiloxane is a silicone oil raw material with low viscosity characteristics. Panthenol, an alcohol derivative of vitamin B5, is one of the moisturizing and soothing ingredients, while beta-glucan is a polysaccharide extracted from oats. Hydroxyethyl cellulose in the thickening and stabilizing components is a water-soluble cellulose ether thickener, and carbomer 940 is a polyacrylic acid crosspolymer, which is widely used in cosmetics as a gel matrix and thickener. Xanthan gum is a microbial polysaccharide produced by Xanthomonas fermentation. Cetearyl alcohol olive oil ester is a plant-derived emulsifier and skin conditioner, which is formed by esterification of olive oil fatty acids and cetearyl alcohol. Cetearyl alcohol is a fatty alcohol composed of cetyl alcohol and stearyl alcohol.

[0025] like Figure 1 As shown, a method for preparing a skin protection composition containing natural antioxidant active substances includes the following preparation process: Step S1, Raw material preparation and inspection; Step S2, aqueous phase preparation; Step S3, oil phase preparation; Step S4, two-step emulsification operation; Step S5, gradient cooling process; Step S6: Post-processing and quality inspection.

[0026] Based on the above technical solution, S1, all raw materials used are subjected to quality inspection and pretreatment, including testing the content of active ingredients, heavy metal residues, pesticide residues and microbial limits of each raw material. After testing, the raw materials are weighed according to the formula dosage. Solid raw materials, including hydroxyethyl cellulose, carbomer 940, and xanthan gum, liquid raw materials, including tocopheryl acetate, caprylic / capric triglycerides, shea butter, and avocado oil, and aqueous raw materials, including deionized water, butylene glycol, and glycerin, were separately placed in labeled sealed containers for classification and later use. Meanwhile, natural antioxidant active substances, including maqui berry extract, sea buckthorn flavonoid extract, and elderberry extract, were placed in glass containers and stored in a dark and low-temperature environment.

[0027] Based on the above technical solution, S2, first add deionized water to a stainless steel preparation tank, start stirring, control the stirring speed to 400 rpm, so that a slight vortex is formed on the water surface, then add butylene glycol and glycerin to the deionized water, and continue stirring for 10 minutes to fully dissolve the moisturizer and mix it evenly with the deionized water. After complete dissolution, the pre-sieved hydroxyethyl cellulose powder is added to the aqueous phase. The hydroxyethyl cellulose powder is added gradually while stirring. After all the powder is added, it is stirred for 30 minutes to form a uniform viscous liquid. Then, carbomer 940 powder is added uniformly to the aqueous phase while stirring. After all the carbomer is added, it is stirred for 45 minutes to allow the carbomer to fully swell and form a transparent gel system. Xanthan gum powder and butylene glycol were premixed to prepare a xanthan gum predispersant solution, which was then slowly added to the aqueous phase while stirring. After all the xanthan gum was added, the mixture was stirred for 20 minutes. Panthenol and β-glucan were dissolved in deionized water and slowly added to the aqueous phase system. The mixture was stirred for 15 minutes. After the mixture was stirred evenly, purslane extract was added to the aqueous phase and the mixture was stirred for another 10 minutes. Arginine was dissolved in deionized water to prepare an arginine solution, which was then slowly added dropwise to the aqueous phase system. The pH value was monitored and adjusted to 6.5-7.0. After the pH adjustment was completed, the mixture was stirred for 10 minutes. Finally, dissolve disodium ethylenediaminetetraacetate in deionized water and add it to the aqueous phase system. Stir for 10 minutes. After the aqueous phase preparation is completed, adjust the temperature of the aqueous phase tank to 72°C and keep it warm. S3, add all oil phase raw materials into a stainless steel oil phase preparation tank. The oil phase raw materials include caprylic / capric triglyceride, tocopheryl acetate, avocado oil, shea butter, polydimethylsiloxane, cetearyl alcohol, and cetearyl oleate. Start the heating and stirring mechanism to heat the oil phase mixture to 78°C. Stir continuously during the heating process to ensure that the oil phase components are fully mixed. After heating the oil phase mixture to 78°C, continue stirring and keep it warm for 15 minutes.

[0028] Based on the above technical solution, in S4, the emulsification operation is carried out while the oil phase is still hot after preparation, and a two-step emulsification method is used to obtain a stable and delicate emulsion system. First, the aqueous phase mixture and the oil phase mixture at 78℃ are filtered separately through a filtration device to remove mechanical impurities and undissolved particles. The filtered oil phase is then slowly injected into the aqueous phase using a fine droplet method, while stirring is started and the stirring speed is controlled at 2500 rpm. After the oil phase is injected, shear stirring is continued, and the emulsification time is not less than 10 minutes to ensure that the oil phase is fully dispersed to form a uniform primary emulsion. During the oil phase injection process, the stirring equipment is kept running continuously to break the oil droplets into fine and uniform particles.

[0029] Then, after emulsification, high-pressure homogenization is performed. The obtained emulsion is transferred to a high-pressure homogenizer and homogenized under a pressure of 28 MPa for 3 cycles, each cycle lasting 5 minutes. After homogenization, samples are taken for testing. A qualified emulsion should be a fine, uniform milky white color with no obvious oil droplets or particles, and no visible oil streaks after being coated on a glass slide.

[0030] Based on the above technical solution, S5, after emulsification is completed, the product is cooled to below room temperature to obtain suitable product consistency and good use stability. First, the emulsification tank is switched to cooling circulation mode, and the cooling rate is controlled to decrease by 0.8℃ per minute. During the cooling process, low-speed stirring is maintained at 80 rpm. When the temperature is cooled to 50°C, add the preservative system. After pre-mixing phenoxyethanol and ethylhexylglycerin evenly, slowly add them to the cooling emulsion system and continue stirring for 15 minutes to fully disperse the preservative. When the temperature continues to cool to 40°C, add the natural antioxidant active ingredients. Pre-dilute the maquill extract, sea buckthorn flavonoid extract and elderberry extract with butylene glycol, and then slowly add them to the emulsion system in sequence. Stir for 5 minutes after each extract is added, and add the next extract after it is fully dispersed. After the last extract is added and stirred, continue to stir the whole mixture for 20 minutes to ensure that the three antioxidant extracts are evenly distributed in the product. Continue cooling until the product is cooled to room temperature of 22°C; S6. After gradient cooling is completed, the product is transferred to a vacuum degassing tank and degassed for 18 minutes under a vacuum of -0.085MPa to remove air bubbles trapped in the product. After degassing is completed, quality inspection is carried out, including: appearance, pH value, viscosity, microbial limit and stability; The product should have a fine, milky-white paste appearance, without obvious particles, bubbles, or stratification. The pH value should be in the range of 6.0-7.0, and the product viscosity should be in the range of 30,000-50,000 mPa·s. The viscosity should be measured using a viscometer. The total bacterial count of the product should be <100 CFU / g, and the mold and yeast count should be <100 CFU / g. The product stability should be tested for stratification by centrifugation acceleration test. For products containing natural antioxidant active substances, accelerated stability tests are also required. The samples are placed in a constant temperature chamber at 40℃±2℃ and the changes in the content of active ingredients are detected after 4 weeks. The anthocyanin content in the maqui berry extract must be maintained at more than 85% of the initial value, the total flavonoid content in the sea buckthorn flavonoid extract must be maintained at more than 90% of the initial value, and the anthocyanin content in the elderberry extract must be maintained at more than 85% of the initial value. After the product quality inspection is passed, it is filled by an automatic cream filling machine, using light-proof plastic bottles with sealed inner caps as packaging containers, and sealed immediately after filling.

[0031] Example 2: This embodiment provides a skin protection composition containing natural antioxidant active substances, the composition of which is as follows: Natural antioxidant active ingredients 10.0%, oil phase ingredients 17.0%, aqueous phase ingredients 64.0%, moisturizing ingredients 4.0%, thickening and stabilizing ingredients 4.5%, auxiliary ingredients 0.5%.

[0032] Among them, the natural antioxidant active ingredients include 3.5% maquillia fruit extract, 3.0% sea buckthorn flavonoid extract, and 3.5% elderberry extract.

[0033] The remaining components and preparation methods are the same as in Example 1.

[0034] Example 3: This embodiment provides a skin protection composition containing natural antioxidant active substances, the composition of which is as follows: The composition consists of 8.0% natural antioxidant active ingredients, 22.0% oil phase ingredients, 60.0% aqueous phase ingredients, 5.0% moisturizing ingredients, 4.5% thickening and stabilizing ingredients, and 0.5% auxiliary ingredients.

[0035] Among them, the natural antioxidant active ingredients include 2.8% maquillia fruit extract, 2.6% sea buckthorn flavonoid extract, and 2.6% elderberry extract.

[0036] The remaining components and preparation methods are the same as in Example 1.

[0037] Example 4: This embodiment provides a skin protection composition containing natural antioxidant active substances, the composition of which is as follows: Natural antioxidant active ingredients 7.0%, oil phase ingredients 12.0%, aqueous phase ingredients 72.0%, moisturizing ingredients 5.5%, thickening and stabilizing ingredients 3.0%, auxiliary ingredients 0.5%.

[0038] Among them, the natural antioxidant active ingredients include 2.5% maquillia fruit extract, 2.0% sea buckthorn flavonoid extract, and 2.5% elderberry extract.

[0039] The remaining components and preparation methods are the same as in Example 1.

[0040] Comparative Example 1: This comparative example provides a skin protection composition that differs from Example 1 in that: only 3.0% of maquillia fruit extract is used as an antioxidant, and the remaining content is made up to 100% by deionized water. No sea buckthorn flavonoid extract or elderberry extract is added. The remaining components and contents are the same as in Example 1, and the preparation method is the same as in Example 1.

[0041] Performance Tests and Results To verify the performance of the compositions of the present invention, tests were conducted on Examples 1-4 and Comparative Example 1.

[0042] The DPPH free radical scavenging experiment was used. The sample was prepared into a 1.0% (w / w) solution and reacted with DPPH solution for 30 min. The free radical scavenging rate was then measured. At the same time, the sample was placed in a 40℃ constant temperature incubator for 4 weeks to detect the retention rate of active ingredients and to measure the product's pH, viscosity and centrifugal stability.

[0043] The test results are as follows: The DPPH radical scavenging rate was 78.6% in Example 1, 85.3% in Example 2, 76.2% in Example 3, 70.5% in Example 4, and 63.5% in Comparative Example 1.

[0044] After being placed at 40°C for 4 weeks, the anthocyanin retention rate in Example 1 was 87.5% and the flavonoid retention rate was 92.1%; in Example 2, the retention rates were 89.2% and 93.4% respectively; in Example 3, the retention rates were 90.5% and 94.0% respectively; in Example 4, the retention rates were 85.6% and 90.2% respectively; and in Comparative Example 1, the anthocyanin retention rate was 72.3%.

[0045] Regarding physical stability, the pH of Examples 1-4 was 6.4-6.7, the viscosity was 30000-48000 mPa·s, and no stratification was observed after centrifugation at 3000 rpm for 30 min; while Comparative Example 1 showed slight stratification.

[0046] The results above show that the present invention significantly improves the free radical scavenging ability of the composition by combining a variety of natural antioxidant active substances, while also enhancing the stability of the active ingredients and the system stability, and has a significant synergistic effect compared with a single antioxidant system.

[0047] Finally, it should be noted that the above descriptions are merely preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A skin protection composition containing natural antioxidant active substances, characterized in that: It includes natural antioxidant active ingredients, oil phase ingredients, aqueous phase ingredients, moisturizing ingredients, thickening and stabilizing ingredients, and auxiliary ingredients; The natural antioxidant active ingredients consist of maquillia fruit extract, sea buckthorn flavonoid extract and elderberry extract; The oil phase component consists of caprylic / capric triglyceride, tocopheryl acetate, avocado oil, shea butter, and polydimethylsiloxane, and the aqueous phase component consists of deionized water, butanediol, and glycerol. The moisturizing component consists of panthenol, purslane extract and β-glucan; the thickening and stabilizing component consists of hydroxyethyl cellulose, carbomer 940, xanthan gum, cetearyl oleate and cetearyl alcohol; and the auxiliary component consists of phenoxyethanol, ethylhexylglycerin, arginine and disodium EDTA.

2. The skin protection composition containing natural antioxidant active substances according to claim 1, characterized in that: The total content of the natural antioxidant active ingredients is 3.5-12.0%, the total content of the oil phase components is 10.0-32.0%, the total content of the aqueous phase components is 42.0-74.0%, the total content of the moisturizing components is 1.2-8.4%, the total content of the thickening and stabilizing components is 2.0-7.1%, and the total content of the auxiliary components is 0.1-1.2%.

3. The skin protection composition containing natural antioxidant active substances according to claim 2, characterized in that: The weight percentages of each component in the natural antioxidant active ingredient composition are as follows: Maquillia fruit extract 0.8-4.4%, sea buckthorn flavonoid extract 1.1-3.6%, elderberry extract 1.2-5.0%; The weight percentages of each composition within the oil phase are as follows: Caprylic / capric triglycerides 2.1-12.0%, tocopheryl acetate 0.5-3.0%, avocado oil 2.2-6.8%, shea butter 1.2-5.3%, polydimethylsiloxane 0.5-6.4%; The weight percentages of each composition within the aqueous phase are as follows: Deionized water 34.0-72.0%, butanediol 2.0-11.0%, glycerol 1.2-7.0%.

4. A skin protection composition containing natural antioxidant active substances according to claim 2, characterized in that: The weight percentages of each component in the moisturizing component are as follows: Panthenol 0.5-3.0%, Portulaca oleracea extract 0.6-4.2%, β-glucan 0.2-1.5%; The weight percentages of each component in the thickening and stabilizing component are as follows: Hydroxyethyl cellulose 0.1-1.2%, Carbomer 940 0.2-1.3%, Xanthan gum 0.1-0.9%, Cetearyl alcohol oleate 0.2-2.2%, Cetearyl alcohol 0.05-1.3%; The weight percentages of each composition within the auxiliary components are as follows: Phenoxyethanol 0.01-0.65%, ethylhexylglycerin 0.01-0.3%, arginine 0.01-0.5%, disodium ethylenediaminetetraacetate 0.01-0.06%.

5. A skin protection composition containing natural antioxidant active substances according to claim 2, characterized in that: The oil phase components include caprylic / capric triglyceride, a light oil formed by esterification of caprylic acid and capric acid with glycerol; tocopheryl acetate, a vitamin E acetate; avocado oil, a plant oil extracted from avocado fruit; shea butter, a plant oil extracted from shea fruit; and polydimethylsiloxane, a silicone oil raw material with low viscosity. Panthenol in the moisturizing and soothing components is an alcohol derivative of vitamin B5, and β-glucan is a polysaccharide extracted from oats or yeast. The hydroxyethyl cellulose in the thickening and stabilizing components is a water-soluble cellulose ether thickener, and carbomer 940 is a polyacrylic acid crosslinking polymer, which is widely used in cosmetics as a gel matrix and thickener. Xanthan gum is a microbial polysaccharide produced by Xanthomonas fermentation. Cetearyl alcohol olive oil ester is a plant-derived emulsifier and skin conditioner, which is formed by esterification of olive oil fatty acids and cetearyl alcohol. Cetearyl alcohol is a fatty alcohol composed of cetyl alcohol and stearyl alcohol.

6. A method for preparing a skin protection composition containing natural antioxidant active substances, characterized in that: The preparation process includes the following: Step S1, Raw material preparation and inspection; Step S2, aqueous phase preparation; Step S3, oil phase preparation; Step S4, two-step emulsification operation; Step S5, gradient cooling process; Step S6: Post-processing and quality inspection.

7. The method for preparing a skin protection composition containing natural antioxidant active substances according to claim 6, characterized in that: S1 involves quality inspection and pretreatment of all raw materials used, including testing the content of active ingredients, heavy metal residues, pesticide residues, and microbial limits of each raw material. After testing, the raw materials are weighed according to the formula dosage. Solid raw materials, liquid raw materials, and aqueous raw materials are classified and stored separately in labeled sealed containers for later use. At the same time, natural antioxidant active substances are stored in glass containers in a dark and low-temperature environment.

8. The skin protection composition containing natural antioxidant active substances and its preparation method according to claim 6, characterized in that: In step S2, first add deionized water to a stainless steel preparation tank, start stirring, then add butylene glycol and glycerin to the deionized water, and continue stirring to fully dissolve the humectant and mix it evenly with the deionized water. After complete dissolution, the pre-sieved hydroxyethyl cellulose powder is added to the aqueous phase. The hydroxyethyl cellulose powder is added gradually while stirring. After all the powder is added, it is stirred to form a uniform viscous liquid. Then, carbomer 940 powder is added uniformly to the aqueous phase while stirring. After all the carbomer is added, it is stirred to allow the carbomer to fully swell and form a transparent gel system. Xanthan gum powder and butylene glycol were premixed to prepare a xanthan gum predispersant solution, which was then slowly added to the aqueous phase while stirring. After all the xanthan gum was added, the mixture was stirred until homogeneous. Panthenol and β-glucan were dissolved in deionized water and slowly added to the aqueous phase system. After stirring until homogeneous, purslane extract was added to the aqueous phase and stirring was continued. Arginine was dissolved in deionized water to prepare an arginine solution, which was then slowly added dropwise to the aqueous phase system. The pH value was monitored and adjusted, and the mixture was stirred until homogeneous. Finally, dissolve disodium ethylenediaminetetraacetate in deionized water and add it to the aqueous phase system. Stir and mix well. After the aqueous phase preparation is completed, adjust the temperature of the aqueous phase tank to 70-75℃ and keep it warm. In step S3, all oil phase raw materials are added to a stainless steel oil phase preparation tank, and the heating and stirring mechanism is started to heat the oil phase mixture to 75-80°C. During the heating process, stirring is continued. After the oil phase mixture is heated to 75-80°C, stirring and heat preservation are continued for 15 minutes.

9. The method for preparing a skin protection composition containing natural antioxidant active substances according to claim 8, characterized in that: In step S4, the emulsification operation is carried out while the oil phase is hot after the oil phase preparation is completed. First, the aqueous phase mixture and the oil phase mixture at 75-80℃ are filtered through a filter device. The filtered oil phase is slowly injected into the aqueous phase by a fine droplet method, while stirring is started. After the oil phase is injected, the shear stirring state is maintained. The emulsification time is not less than 10 minutes. Then, after emulsification, high-pressure homogenization is performed. The obtained emulsion is transferred to a high-pressure homogenizer for circulating homogenization. The number of cycles is 3, and the cycle time is 5 minutes each time. After homogenization is completed, samples are taken for testing.

10. The method for preparing a skin protection composition containing natural antioxidant active substances according to claim 9, characterized in that: In step S5, after emulsification is completed, the product is cooled to below room temperature. First, the emulsification tank is switched to cooling circulation mode, and the cooling rate is controlled to decrease by 0.5-1.0℃ per minute. During the cooling process, low-speed stirring is maintained. When the temperature is cooled to 50-55℃, phenoxyethanol and ethylhexylglycerin are premixed evenly and then slowly added to the cooling emulsion system. Stirring is continued for 15 minutes to ensure that the preservative is fully dispersed. When the temperature continues to cool to 40-45℃, the extracts of Maquillicium erinaceus, Hippophae rhamnoides and Elderberry are pre-diluted with butylene glycol and then slowly added to the emulsion system in sequence. After each extract is added, the mixture is stirred for 5 minutes. After the mixture is fully dispersed, the next extract is added. After the last extract is added, the mixture is stirred again. Continue cooling until the product is cooled to room temperature; In step S6, after gradient cooling is completed, the product is transferred to a vacuum degassing tank and degassed under a vacuum of -0.08 to -0.09 MPa to remove air bubbles trapped in the product. After degassing, quality inspection is carried out. The inspection items include: appearance, pH value, viscosity, microbial limit and stability. For products containing natural antioxidant active substances, accelerated stability test is also required. After the product quality inspection is passed, it is filled by an automatic cream filling machine, using light-proof plastic bottles with sealed inner caps as packaging containers, and sealed immediately after filling.

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