An electrode lead and a nerve stimulation system

Abstract

This invention discloses an electrode lead and a nerve stimulation system. The electrode lead includes a stimulation segment, a connecting segment, and an intermediate segment. The stimulation segment includes several stimulation contacts and at least one filter, one end of which is electrically connected to at least one stimulation contact. The intermediate segment includes multiple core wires, each core wire including at least one first transmission line for transmitting stimulation signals and at least one second transmission line for transmitting interference signals. The connecting segment includes several connection contacts and a consumption module. The two ends of the first transmission lines are electrically connected to the connection contacts and the filter, respectively, and the two ends of the second transmission lines are electrically connected to the consumption module and the filter, respectively. The electrode lead of this application can prevent interference signals from entering the stimulation segment, ensuring the stability of the stimulation signal output, improving the MRI compatibility of the electrode lead, and enhancing the therapeutic effect and patient comfort. In particular, it can prevent abnormal heating of the stimulation contacts, thereby avoiding damage to the patient.

Description

Technical Field

[0001] This invention relates to the field of implantable medical device technology, and more particularly to an electrode lead and a nerve stimulation system. Background Technology

[0002] With the development of neurostimulation technology, it is possible to modulate the function of nerves, muscles, or other tissues through electric current or electrical pulses, helping to treat many different types of diseases, especially those of the nervous and motor systems. Electrode leads are devices used to deliver electric current or other forms of stimulation signals to specific target areas. Electrode leads are commonly implanted in patients to provide electrical stimulation to the affected areas.

[0003] Because electrode leads need to be implanted into the patient's body, they require excellent flexibility and tensile strength, and are typically spirally wound. However, when these spiral electrode leads are in environments with interference, such as MRI or electromagnetic waves, interference signals can be generated in the stimulation circuit. These interference signals, such as induced current or interfering current, can cause changes in the magnitude and frequency of the current in the circuit, affecting the stability of the stimulation signal output and leading to variations in the electrical stimulation effect. This can cause discomfort to the patient, and in particular, interference signals can cause an abnormal increase in the output signal of the stimulation electrode, affecting the treatment effect and even causing abnormal heating of the stimulation contacts, resulting in irreversible damage to the patient, such as burns to the brain nuclei.

[0004] Therefore, the existing electrode wires need to be improved. Summary of the Invention

[0005] The purpose of this invention is to provide an electrode lead and a nerve stimulation system that, while ensuring that the electrode lead has good flexibility and tensile strength, can prevent interference signals from entering the stimulation segment, ensure the stability of the stimulation signal output, improve the MRI compatibility of the electrode lead, improve the therapeutic effect and patient comfort, and in particular, can prevent abnormal heating of the stimulation contact point, thereby avoiding damage to the patient.

[0006] The objective of this invention is achieved through the following technical solution:

[0007] An electrode lead includes a stimulation segment for providing electrical stimulation, a connection segment electrically connected to a stimulator, and an intermediate segment connecting the stimulation segment and the connection segment. The stimulation segment includes a plurality of stimulation contacts and at least one filter, one end of which is electrically connected to at least one stimulation contact. The intermediate segment includes a plurality of core wires, each core wire including at least one first transmission line for transmitting stimulation signals and at least one second transmission line for transmitting interference signals. The connection segment includes a plurality of connection contacts and a consumable module.

[0008] One end of the first transmission line is electrically connected to the connection contact of the connection segment, and the other end of the first transmission line is electrically connected to the filter. One end of the second transmission line is electrically connected to the consumption module, and the other end of the second transmission line is electrically connected to the filter.

[0009] Preferably, the filter has a first end and a second end disposed opposite to each other. The first end of the filter has a first contact and a second contact. The first contact is electrically connected to the first transmission line, and the second contact is electrically connected to the second transmission line. The second end of the filter has a third contact, and the third contact is electrically connected to the stimulation contact of the stimulation segment.

[0010] The filter further includes at least one first internal circuit and at least one second internal circuit. The first contact and the third contact are electrically connected through the first internal circuit, and the first internal circuit is electrically connected to the second contact through the second internal circuit.

[0011] Preferably, the number of filters is one, the number of the first internal circuits and the number of the first contacts are the same as the number of the first transmission lines, the number of the second contacts is one, and the number of the third contacts is the same as the number of the stimulation contacts.

[0012] Preferably, when there are multiple first internal circuits and second internal circuits, the first internal circuits are independent of each other, one end of the second internal circuit is electrically connected to the first internal circuit in a one-to-one correspondence, and the other end of all the second internal circuits is electrically connected to the second contact.

[0013] Preferably, there are multiple first transmission lines and one second transmission line. The first transmission line is electrically connected to the first contact in a one-to-one correspondence, and the second transmission line is electrically connected to the second contact.

[0014] Preferably, there are multiple first transmission lines and multiple second transmission lines. The first transmission lines are electrically connected to the first contacts in a one-to-one correspondence, and all the second transmission lines are electrically connected to the second contacts simultaneously.

[0015] Preferably, there are multiple filters, the number of filters is the same as the number of stimulation contacts, and the filters are electrically connected to the stimulation contacts in a one-to-one correspondence.

[0016] The number of filters is the same as the number of the first transmission lines, and the filters are electrically connected to the first transmission lines in a one-to-one correspondence.

[0017] Preferably, the filter includes a first internal circuit and a second internal circuit, one end of the second internal circuit being electrically connected to the first internal circuit, and the other end of the second internal circuit being electrically connected to the second contact.

[0018] Preferably, when the number of the first transmission lines and the number of the second transmission lines are the same, the first transmission lines are electrically connected to the first contacts in a one-to-one correspondence, and the second transmission lines are electrically connected to the second contacts in a one-to-one correspondence.

[0019] Preferably, when there are multiple first transmission lines and one second transmission line, the first transmission line is electrically connected to the first contact in a one-to-one correspondence, and all second contacts are electrically connected to the second transmission line.

[0020] Preferably, the filter includes one or more inductors connected in series in a first internal circuit between the first contact and the third contact, such that the inductors are connected in series with the first transmission line; and / or,

[0021] The filter includes one or more capacitors, which are disposed in the second internal circuit. The capacitors are connected in parallel with the first transmission line, and in series with the second transmission line; and / or...

[0022] The filter includes one or more diodes, which are disposed on the second internal circuit and between the capacitor and the first transmission line.

[0023] Preferably, the consumption module is a connecting block, which is used to electrically connect the second transmission line to the stimulator; or,

[0024] The consumption module is a load, which is used to convert the interference signal into heat.

[0025] Preferably, when the consumption module is a connection block, the connection block includes a first part and a second part that are connected to each other. The first part is disposed at one end of the connection segment away from the middle segment. The first part is used to be electrically connected to the ground terminal of the stimulator, or the first part is used to be electrically connected to the converter of the stimulator so that the interference signal is converted into a current for charging the stimulator.

[0026] The electrode wire is generally cylindrical, and an accommodating space is formed inside the electrode wire extending along the axial direction of the electrode wire. The second part is disposed in the accommodating space and is electrically connected to the second transmission line.

[0027] Preferably, the second transmission line is electrically connected to the second part by welding.

[0028] Preferably, multiple core wires are twisted together to form a conductor wire, each core wire including a conductor and an insulating layer, the insulating layer covering the conductor, and each core wire including at least one conductor;

[0029] The guidewire also includes an outer sheath layer, which covers the core wire.

[0030] Preferably, the guide wire is spirally wound along the axial direction of the electrode wire;

[0031] When the number of guidewires is multiple strands, the multiple strands of guidewires are wound in a spiral shape with the same spiral direction.

[0032] A neural stimulation system, comprising:

[0033] Stimulator;

[0034] The electrode wire as described in any of the above, one end of which is implanted in the patient's body, and the other end of which is electrically connected to the stimulator.

[0035] Preferably, the electrode lead consumption module is electrically connected to the stimulator; or,

[0036] The neurostimulation system also includes extension leads, and the electrode lead consumption module is electrically connected to the stimulator through the extension leads.

[0037] Compared with the prior art, the beneficial effects of the present invention include at least the following:

[0038] The electrode lead and neurostimulation system of the present invention, by setting a first transmission line and a second transmission line, wherein one end of the first transmission line is electrically connected to the connecting contact of the connecting segment, and the other end of the first transmission line is electrically connected to the stimulation contact of the stimulation segment through a filter, the first transmission line is used to transmit the stimulation signal to the stimulation contact of the stimulation segment, the filter is used to prevent interference signals from entering the stimulation segment, and the second transmission line is used to eliminate interference signals. In this way, while ensuring that the electrode lead has good flexibility and tensile strength, when the spiral electrode lead is in an environment with interference, such as an NMR or electromagnetic wave environment, interference signals will be generated in the stimulation circuit of the electrode lead. The interference signals, such as induced current or interference current, cause changes in the current magnitude and frequency of the circuit. The filter can prevent interference signals from entering the stimulation segment, and the second transmission line can extract the interference signals from the stimulation circuit, ensuring the stability of the stimulation signal output, improving the NMR compatibility of the electrode lead, improving the treatment effect and patient comfort, and especially preventing abnormal heating of the stimulation contact, thereby avoiding damage to the patient, such as avoiding burns to the patient's brain nuclei. Attached Figure Description

[0039] Figure 1 This is a schematic diagram of the structure of the electrode wire in an embodiment of the present invention.

[0040] Figure 2 This is an exploded view of the electrode wires according to an embodiment of the present invention.

[0041] Figure 3 yes Figure 2 A magnified view of a portion of point A in the middle.

[0042] Figure 4 yes Figure 2 A magnified view of a portion of point B in the middle.

[0043] Figure 5 This is a schematic diagram of the guide wire and filter in an embodiment of the present invention.

[0044] Figure 6 yes Figure 5 A magnified view of a portion of point C.

[0045] Figure 7 This is a schematic diagram of the guidewire structure in an embodiment of the present invention.

[0046] Figure 8 yes Figure 7 A magnified view of a portion of point D.

[0047] Figure 9 This is a schematic diagram of the filter structure in an embodiment of the present invention.

[0048] Figure 10 This is a schematic diagram of a filter according to an embodiment of the present invention.

[0049] Figure 11 This is a schematic diagram of another filter in an embodiment of the present invention.

[0050] In the diagram: 100, Electrode wire; 1, Stimulation section; 11, Stimulation contact; 12, First support; 2, Connecting section; 21, Connecting contact; 22, Second support; 3, Middle section; 31, Guide wire; 311, Core wire; 3111, First transmission line; 3112, Second transmission line; 3113, Conductor; 3114, Insulating layer; 312, Outer sheath; 32, First protective shell; 33, Second protective shell; 4, Filter; 41, First end; 411, First contact; 412, Second contact; 42, Second end; 421, Third contact; 43, Connecting wire; 44, Inductor coil; 45, Capacitor; 46, Diode; 47, First internal circuit; 48, Second internal circuit; 5, Consumable module; 51, Connecting block; 511, First part; 512, Second part; 6, Accommodation space. Detailed Implementation

[0051] Exemplary embodiments will now be described more fully with reference to the accompanying drawings. However, these exemplary embodiments can be implemented in many forms and should not be construed as limited to the embodiments set forth herein; rather, they are provided to make the invention more comprehensive and complete, and to fully convey the concept of the exemplary embodiments to those skilled in the art. The same reference numerals in the drawings denote the same or similar structures, and therefore repeated descriptions of them will be omitted.

[0052] The terms used to express position and direction in this invention are illustrated with the accompanying drawings, but changes can be made as needed, and all such changes are included within the scope of protection of this invention.

[0053] Reference Figures 1 to 11 The present invention provides an electrode wire 100 for electrically connecting a stimulator (not shown) and a stimulation contact 11. The stimulator may be a pulse generator, which transmits stimulation signals to the stimulation contact 11 through the electrode wire 100. The stimulation contact 11 can provide electrical stimulation to the patient's affected area.

[0054] Reference Figure 1 , Figure 2 The electrode lead 100 may include a stimulation segment 1 for providing electrical stimulation to the patient's affected area, a connecting segment 2 electrically connected to a stimulator, and an intermediate segment 3 connecting the stimulation segment 1 and the connecting segment 2. In some embodiments, the connecting segment 2 may be electrically connected to the stimulator via an extension lead (not shown). The stimulation segment 1 and the connecting segment 2 may be respectively located at both ends of the intermediate segment 3, i.e., the intermediate segment 3 serves to connect the stimulation segment 1 and the connecting segment 2. The intermediate segment 3 is used to transmit the stimulation signal from the connecting segment 2 to the stimulation segment 1, which provides electrical stimulation to the patient's affected area.

[0055] Specifically, refer to Figure 4 The connecting segment 2 is provided with a plurality of connecting contact points 21 and a consumption module 5, that is, the connecting segment 2 is provided with one or more connecting contact points 21 and a consumption module 5. In this embodiment, the connecting segment 2 may be provided with multiple connecting contact points 21, and the stimulator can provide multiple stimulation signals through multiple connecting contact points 21. The multiple connecting contact points 21 are arranged at intervals to avoid mutual interference between the connecting contact points 21, thereby avoiding mutual interference between the stimulation signals of the stimulator. The consumption module 5 can export or consume the interference signals in the circuit to prevent the interference signals from interfering with the stimulation signals in the circuit.

[0056] The connecting contacts 21 of the connecting segment 2 can be one or more of the form of a sheet or a ring, and can be set according to actual needs. In this embodiment, the connecting contacts 21 of the connecting segment 2 are ring-shaped, and the connecting segment 2 may also include a second support portion 22. The second support portion 22 is made of insulating material, and the second support portion 22 and the connecting contacts 21 can be distributed at intervals. The second support portion 22 can ensure that the connecting contacts 21 are mutually insulated.

[0057] The connecting contact 21 can be directly electrically connected to the stimulator, or it can be electrically connected to the stimulator via an extension wire (not shown). The extension wire effectively extends the distance between the electrode wire 100 and the stimulator, allowing the same stimulator to provide stimulation signals to patients in different positions, thus increasing the application scenarios of the stimulator.

[0058] Reference Figure 3 The stimulation segment 1 is provided with a plurality of stimulation contacts 11 and at least one filter 4. That is, the stimulation segment 1 is provided with one or more stimulation contacts 11 and at least one filter 4. The stimulation contacts 11 are exposed on the outer surface of the stimulation segment 1 to ensure good contact between the stimulation contacts 11 and the patient's affected area, thereby ensuring that the stimulation contacts 11 can provide electrical stimulation to the patient's affected area. In this application, the stimulation segment 1 may be provided with multiple stimulation contacts 11, which are spaced apart from each other to avoid mutual interference, thereby ensuring the accuracy of electrical stimulation by the stimulation contacts 11 and improving the treatment effect.

[0059] The stimulation contacts 11 of stimulation segment 1 can be one or more of the following shapes: sheet-like or annular, depending on actual needs. In this embodiment, some stimulation contacts 11 can be sheet-like, and some can be annular. Stimulation segment 1 may also include a first support portion 12, on which the stimulation contacts 11 can be disposed. The first support portion 12 is made of insulating material and provides support for the stimulation contacts 11 while ensuring that the stimulation contacts 11 are insulated from each other. The end of the first support portion 12 away from the intermediate segment 3 has a smooth end face, such as a hemispherical protrusion. By making the end of the first support portion 12 away from the intermediate segment 3 a smooth end face, damage to human tissue can be reduced when implanting the electrode wire 100.

[0060] Since the electrode lead 100 needs to be implanted into the patient's body, it requires excellent flexibility and tensile strength. The electrode lead 100 is typically spirally wound to increase its tensile and bending strength, ensuring smooth implantation and preventing breakage. When the spiral electrode lead 100 is in an environment with interference, such as MRI or electromagnetic waves, interference signals will be generated in the stimulation circuit. These interference signals, such as induced current or interfering current, will cause changes in the magnitude and frequency of the current in the circuit, affecting the stability of the stimulation signal output and causing variations in the electrical stimulation effect. This can lead to patient discomfort, and in particular, interference signals can cause abnormally increased output signals from the stimulation electrode, affecting the treatment effect and even causing abnormal heating of the stimulation contact 11, resulting in irreversible damage to the patient, such as burns to the brain nuclei.

[0061] When the spiral electrode lead 100 is in an environment with interference, in order to prevent interference signals from being generated in the stimulation circuit of the electrode lead 100, causing changes in the current magnitude and frequency of the circuit, and affecting the stability of the stimulation signal output, a filter 4 can be set between the stimulation segment 1 and the intermediate segment 3. The filter 4 can block interference signals from entering the stimulation segment 1, thereby ensuring the stability of the stimulation signal output, improving the MRI compatibility of the electrode lead 100, improving the treatment effect and patient comfort, and especially preventing abnormal heating of the stimulation contact 11, thereby avoiding damage to the patient, such as preventing burns to the patient's brain nuclei. The filter 4 can be one or more of a low-pass filter 4, a high-pass filter 4, a band-pass filter 4, or a band-stop filter 4, which can be selected according to actual needs.

[0062] Reference Figure 6 , Figure 7 , Figure 8 The intermediate segment 3 may include multiple core wires 311, among which at least one first transmission line 3111 for transmitting stimulation signals and at least one second transmission line 3112 for transmitting interference signals. One end of the first transmission line 3111 can be electrically connected to the connection contact 21 of the connecting segment 2, and the other end of the first transmission line 3111 can be electrically connected to the filter 4. That is, the other end of the first transmission line 3111 can be electrically connected to the stimulation contact 11 of the stimulation segment 1 through the filter 4. The first transmission line 3111 is used to transmit stimulation signals to the stimulation contact 11 of the stimulation segment 1, that is, the first transmission line 3111 transmits stimulation signals to the stimulation contact 11 of the stimulation segment 1 through the filter 4. The filter 4 is used to prevent interference signals from entering the stimulation segment 1. One end of the second transmission line 3112 can be electrically connected to the consumption module 5, and the other end of the second transmission line 3112 can be electrically connected to the filter 4. The second transmission line 3112 is used to transmit interference signals to the consumption module 5.

[0063] Reference Figure 8 The core wire 311 may include a conductor 3113 and an insulating layer 3114. The insulating layer 3114 covers the conductor 3113. Each core wire 311 includes at least one conductor 3113, that is, each core wire 311 may include one or more conductors 3113. The insulating layer 3114 can electrically isolate the conductor 3113 from other components, ensuring that the conductor 3113 transmits the stimulation signal to a preset position. When there are multiple core wires 311, the insulating layer 3114 can also prevent adjacent core wires 311 from interfering with each other.

[0064] As a preferred method, refer to Figure 3 , Figure 6 , Figure 7 , Figure 8 Multiple core wires 311 can be twisted together to form at least one guide wire 31, that is, the multiple core wires 311 in the middle section 3 can be twisted together to form one guide wire 31 or multiple guide wires 31. This can prevent the multiple core wires 311 from becoming loose, and make the multiple core wires 311 more tightly packed, which can reduce the space occupied by the guide wires 31, thereby reducing the overall size of the electrode wire 100. At the same time, it can also prevent the position of the core wires 311 from shifting, ensuring the stability of the connection between the core wires 311 and the filter 4 and the connection contact point 21.

[0065] Reference Figure 6 , Figure 8 The guide wire 31 may also include an outer sheath 312, which can cover the core wire 311. The outer sheath 312 not only protects the core wire 311 but also prevents it from becoming loose. In particular, when there are many core wires 311, it can make the multiple core wires 311 more tightly packed, further reducing the space occupied by the guide wire 31 and thus reducing the overall size of the electrode wire 100. At the same time, it can also prevent the core wires 311 from shifting position, ensuring the stability of the connection between the core wires 311 and the filter 4 and the connection contact point 21. In addition, the core wires 311 are not shifted, which facilitates the sorting of the core wires 311 and makes it easier to solder the core wires 311 to the filter 4 and the connection contact point 21 respectively.

[0066] In this embodiment, refer to Figure 3 , Figure 4The guidewire 31 can be spirally wound along the axis of the electrode wire 100. When the guidewire 31 is multi-stranded, the multi-stranded guidewire 31 is spirally wound in the same spiral direction. The multi-stranded guidewire 31 can be electrically connected to multiple connecting contact points 21 and multiple stimulation contact points 11. The multi-stranded guidewire 31 can transmit multiple stimulation signals to the stimulation contact points 11. The multiple stimulation contact points 11 can provide multiple or more stimulation signals to the patient's affected area, and can also provide electrical stimulation to different parts of the patient, thereby improving treatment efficiency and treatment effect.

[0067] As an example, the intermediate segment 3 may include eight guide wires 31, each guide wire 31 may include two core wires 311, and the two core wires 311 include a first transmission line 3111 and a second transmission line 3112. The eight guide wires 31 may be connected to eight filters 4, and the eight filters 4 may be connected to eight stimulation contacts 11. The stimulator can perform electrical stimulation simultaneously through the eight guide wires 31, or it can perform electrical stimulation through a portion of the guide wires 31.

[0068] Reference Figure 2 , Figure 3 The intermediate section 3 may further include a first protective shell 32, which is sleeved on the outside of the eight-strand guidewire 31 and provides protection for the guidewire 31. The intermediate section 3 may also include a second protective shell 33, which is sleeved on the outside of the first protective shell 32. The second protective shell 33 not only protects the first protective shell 32, but also connects with the first support portion 12 and the second support portion 22 to form a sealed cavity, which can prevent the patient's bodily fluids from entering the cavity.

[0069] In this application, by setting a first transmission line 3111 and a second transmission line 3112, one end of the first transmission line 3111 is electrically connected to the connection contact 21 of the connection segment 2, and the other end of the first transmission line 3111 is electrically connected to the stimulation contact 11 of the stimulation segment 1 through a filter 4. The first transmission line 3111 is used to transmit the stimulation signal to the stimulation contact 11 of the stimulation segment 1, the filter 4 is used to prevent interference signals from entering the stimulation segment 1, and the second transmission line 3112 is used to eliminate interference signals. In this way, while ensuring that the electrode wire 100 needs to have good flexibility and tensile strength, when the spiral electrode wire 100 exists... In environments with interference, such as those involving MRI or electromagnetic waves, interference signals can be generated in the stimulation circuit of the electrode lead 100. These interference signals, such as induced current or interference current, can cause changes in the magnitude and frequency of the current in the circuit. The filter 4 can prevent interference signals from entering the stimulation segment 1. The interference signals can be extracted from the stimulation circuit through the second transmission line 3112, ensuring the stability of the stimulation signal output, improving the MRI compatibility of the electrode lead 100, and enhancing the treatment effect and patient comfort. In particular, it can prevent abnormal heating of the stimulation contact 11, thereby avoiding damage to the patient, such as preventing burns to the patient's brain nuclei. Furthermore, the filter 4 in this application is small in size, allowing for the installation of multiple filters 4. This enables the use of multiple guidewires 31 for stimulation signal transmission. Multiple filters 4 can remove interference signals from multiple stimulation signals, ensuring the stability of the multiple stimulation signal outputs while the electrode lead 100 transmits them.

[0070] In one specific implementation, refer to Figure 9 The filter 4 may have a first end 41 and a second end 42 arranged opposite to each other. The first end 41 of the filter 4 may have a first contact 411 and a second contact 412. The first contact 411 may be electrically connected to the first transmission line 3111, and the second contact 412 may be electrically connected to the second transmission line 3112. The second end 42 of the filter 4 may have a third contact 421, which is electrically connected to the stimulation contact 11 of the stimulation segment 1. That is, the third contact 421 may be electrically connected to the stimulation contact 11 of the stimulation segment 1 via a connecting wire 43. The first contact 411 and the third contact 421 are also electrically connected. The first transmission line 3111 transmits the stimulation signal to the third contact 421 through the first contact 411, and the third contact 421 transmits the stimulation signal to the stimulation contact 11 through the connecting wire 43. The stimulation contact 11 provides electrical stimulation to the patient's affected area.

[0071] Reference Figure 10 , Figure 11The filter 4 may also include at least one first internal circuit 47 and at least one second internal circuit 48. The first contact 411 and the third contact 421 can be electrically connected through the first internal circuit 47, and the first internal circuit 47 can be electrically connected to the second contact 412 through the second internal circuit 48.

[0072] The number of filters 4 can be one or more, and the number of first contacts 411, second contacts 412 and third contacts 421 on each filter 4 can be one or more.

[0073] When there is only one filter 4, the number of first internal circuits 47 and first contacts 411 can be the same as the number of first transmission lines 3111. The number of second contacts 412 can be one, and the number of third contacts 421 can be the same as the number of stimulation contacts 11. That is, when there are multiple first internal circuits 47 and first contacts 411, there are multiple first transmission lines 3111. The first internal circuits 47 and first contacts 411 are electrically connected in a one-to-one correspondence, and the first transmission lines 3111 are electrically connected in a one-to-one correspondence with the first contacts 411. The number of third contacts 421 is also the same as the number of first internal circuits 47. The third contacts 421 are electrically connected in a one-to-one correspondence with the first internal circuits 47, and the third contacts 421 are electrically connected in a one-to-one correspondence with the stimulation contacts 11.

[0074] Reference Figure 11 When there are multiple first internal circuits 47 and multiple second internal circuits 48, the multiple first internal circuits 47 are independent of each other. One end of the second internal circuit 48 can be electrically connected to the first internal circuit 47 in a one-to-one correspondence, that is, one second internal circuit 48 is electrically connected to one first internal circuit 47. The other end of all second internal circuits 48 can be electrically connected to the second contact 412.

[0075] When there are multiple first transmission lines 3111 and one second transmission line 3112, the first transmission line 3111 can be electrically connected to the first contact 411 in a one-to-one correspondence, and the second transmission line 3112 can be electrically connected to the second contact 412.

[0076] When there are multiple first transmission lines 3111 and multiple second transmission lines 3112, the first transmission lines 3111 can be electrically connected to the first contact 411 one by one, and all the second transmission lines 3112 can be electrically connected to the second contact 412 simultaneously.

[0077] As an example, when the filter 4 has eight first contacts 411, one second contact 412, and eight third contacts 421, the number of first transmission lines 3111 is eight, the number of second transmission lines 3112 is one or more, the number of first internal circuits 47 is eight, and the number of second internal circuits 48 is eight. The eight first transmission lines 3111 are electrically connected to the eight first contacts 411 in a one-to-one correspondence, the eight stimulation contacts 11 are electrically connected to the eight third contacts 421 in a one-to-one correspondence, and all second transmission lines 3112 can be electrically connected to the second contacts 412 simultaneously.

[0078] When there are multiple filters 4, the number of filters 4 can be the same as the number of stimulation contacts 11, and the filters 4 can be electrically connected to the stimulation contacts 11 in a one-to-one correspondence. The number of filters 4 can also be the same as the number of first transmission lines 3111, and the filters 4 can be electrically connected to the first transmission lines 3111 in a one-to-one correspondence.

[0079] Reference Figure 10 The filter 4 may include a first internal circuit 47 and a second internal circuit 48. One end of the second internal circuit 48 may be electrically connected to the first internal circuit 47, and the other end of the second internal circuit 48 may be electrically connected to the second contact 412. Each filter 4 has one first contact 411, one second contact 412, and one third contact 421. The two ends of the first internal circuit 47 may be electrically connected to the first contact 411 and the third contact 421, respectively. The first internal circuit 47 may be electrically connected to the second contact 412 through the second internal circuit 48.

[0080] When the number of first transmission lines 3111 and the number of second transmission lines 3112 are the same, the first transmission lines 3111 can be electrically connected to the first contacts 411 in a one-to-one correspondence, and the second transmission lines 3112 can be electrically connected to the second contacts 412 in a one-to-one correspondence. This facilitates the connection of the first transmission lines 3111 and the second transmission lines 3112 to the filter 4, preventing errors in the connection of the first transmission lines 3111 and the second transmission lines 3112 to the filter 4. This ensures the accurate transmission of the stimulation signal and avoids affecting the treatment effect or even causing damage to the patient due to incorrect connection of the first transmission lines 3111 and the second transmission lines 3112 to the filter 4.

[0081] As an example, when there are eight filters 4, each filter 4 has one first contact 411, one second contact 412, and one third contact 421. There are eight first transmission lines 3111 and eight second transmission lines 3112. The eight first transmission lines 3111 and the eight second transmission lines 3112 are electrically connected to the eight first contacts 411 and the eight second contacts 412 respectively. The eight stimulation contacts 11 are electrically connected to the eight third contacts 421 respectively.

[0082] When there are eight filters 4, each filter 4 has one first contact 411, one second contact 412, and one third contact 421. Each guidewire 31 can include two core wires 311, which include one first transmission line 3111 and one second transmission line 3112. The number of filters 4 is the same as the number of guidewires 31. The eight guidewires 31 can be electrically connected to the eight filters 4 in a one-to-one correspondence. The eight filters 4 can be electrically connected to the eight stimulation contacts 11 in a one-to-one correspondence. The stimulator can perform electrical stimulation simultaneously through the eight guidewires 31, or it can perform electrical stimulation through a portion of the guidewires 31.

[0083] When there are multiple first transmission lines 3111 and one second transmission line 3112, the first transmission line 3111 can be electrically connected to the first contact 411 in a one-to-one correspondence, and all the second contacts 412 can be electrically connected to the second transmission line 3112. That is, one second transmission line 3112 can be electrically connected to multiple second contacts 412 at the same time. This can reduce the number of second transmission lines 3112, thereby greatly reducing the volume of the electrode wire 100.

[0084] As an example, when there are eight filters 4, each filter 4 has one first contact 411, one second contact 412, and one third contact 421. There are eight first transmission lines 3111 and one second transmission line 3112. The eight first transmission lines 3111 are electrically connected to the eight first contacts 411 respectively, and one second transmission line 3112 is electrically connected to the eight second contacts 412 simultaneously. The eight stimulation contacts 11 are electrically connected to the eight third contacts 421 respectively.

[0085] As a preferred method, refer to Figure 3 The connecting wire 43 is preferably set in a straight line. When the spiral electrode wire 100 is in an environment with interference, this can avoid the generation of interference signals on the connecting wire 43, thereby ensuring the stability of the stimulation signal output, improving the MRI compatibility of the electrode wire 100, improving the treatment effect and patient comfort, and especially avoiding abnormal heating of the stimulation contact 11, thereby avoiding damage to the patient, such as avoiding burns to the patient's brain nuclei.

[0086] In some embodiments, the number of core wires 311 in a single conductor wire 31 can exceed two. The number of core wires 311 can be odd or even. Multiple core wires 311 can be divided into two strands, one of which can serve as a first transmission line 3111 and the other as a second transmission line 3112. Preferably, the number of core wires 311 is even, and the multiple core wires 311 can be evenly divided into two strands, one of which can serve as the first transmission line 3111 and the other as the second transmission line 3112. Furthermore, the multiple core wires 311 are preferably of the same specification, such as having the same material and size. This allows the impedance of the first transmission line 3111 and the second transmission line 3112 to be matched, further improving the NMR compatibility of the electrode conductor 100.

[0087] When the same guidewire 31 includes multiple first transmission lines 3111, the two ends of the multiple first transmission lines 3111 can be electrically connected to the same connecting contact point 21 and the same stimulation contact point 11, respectively. This can prevent the stimulation signal from failing to be transmitted due to the breakage of some of the first transmission lines 3111, thus improving the stability of the stimulation signal transmission by the first transmission lines 3111. When the same guidewire 31 includes multiple second transmission lines 3112, the multiple second transmission lines 3112 are used to transmit the same interference signal. This can also prevent the interference signal from failing to be transmitted due to the breakage of some of the second transmission lines 3112, thus improving the stability of the interference signal transmission by the second transmission lines 3112.

[0088] Each third contact 421 can be electrically connected to one or more connecting wires 43, that is, each third contact 421 is electrically connected to a stimulation contact 11 through one or more connecting wires 43. When each third contact 421 is electrically connected to a stimulation contact 11 through multiple connecting wires 43, it can prevent the stimulation signal from failing to be transmitted due to the breakage of some connecting wires 43, thereby improving the stability of the stimulation signal transmission by the connecting wires 43.

[0089] As an example, refer to Figure 10 , Figure 11 The filter 4 may be equipped with one or more inductor coils 44. The inductor coils 44 are connected in series with the first internal circuit 47 between the first contact 411 and the third contact 421, so that the inductor coils 44 are connected in series with the first transmission line 3111. The inductor coils 44 can prevent interference signals from entering the stimulation segment 1. Thus, the interference signals generated in the circuit cannot enter the stimulation segment 1, thereby ensuring the stability of the stimulation signal output, improving the MRI compatibility of the electrode wire 100, improving the treatment effect and patient comfort, and especially preventing abnormal heating of the stimulation contact 11, thereby avoiding damage to the patient, such as avoiding burns to the patient's brain nuclei.

[0090] Reference Figure 10 , Figure 11 The filter 4 may also include one or more capacitors 45. The capacitors 45 can be set on the second internal circuit 48. The capacitors 45 can be set in parallel with the first transmission line 3111 and in series with the second transmission line 3112. The capacitors 45 can prevent interference signals generated on the constant interference signal transmission line, especially DC current, from being conducted to the first transmission line 3111, thereby reducing the burden on the filter 4 and improving the anti-interference capability of the filter 4.

[0091] Reference Figure 10 , Figure 11 The filter 4 may also include one or more diodes 46. The diodes 46 can be placed on the second internal circuit 48 and between the capacitor 45 and the first transmission line 3111. Interference signals on the first transmission line 3111 can enter the second transmission line 3112 through the diodes 46, while interference signals on the second transmission line 3112 cannot enter the first transmission line 3111 through the diodes 46. This reduces interference signals on the stimulation circuit, thereby ensuring the stability of the stimulation signal output, improving the MRI compatibility of the electrode lead 100, and enhancing the treatment effect and patient comfort.

[0092] In one specific embodiment, the consumption module 5 can be a connection block 51, which is used to electrically connect the second transmission line 3112 to the stimulator and can transmit interference signals to the stimulator.

[0093] The consuming module 5 can also be a load (not shown) used to convert the interference signal into heat. The load is, for example, a resistor, which can dissipate the interference signal as heat.

[0094] As an example, refer to Figure 4 The connecting block 51 can be made of metal, and the cross-section of the connecting block 51 along the axial direction of the electrode wire 100 can be T-shaped. When the consumable module 5 is the connecting block 51, the connecting block 51 can include a first part 511 and a second part 512. The first part 511 and the second part 512 can be connected to each other. The first part 511 of the connecting block 51 can be circular, and the first part 511 can be located at the end of the connecting segment 2 away from the middle segment 3.

[0095] Specifically, the first portion 511 can be electrically connected to the ground terminal (not shown) of the stimulator, and the first portion 511 can be electrically connected to the ground terminal on the stimulator's PCB board (not shown). The ground terminal of the stimulator can be located on the stimulator's PCB board. In some embodiments, the first portion 511 can be electrically connected to an extension wire, and the first portion 511 can be electrically connected to the ground terminal on the stimulator's PCB board via the extension wire.

[0096] The first part 511 can also be electrically connected to a converter (not shown) of the stimulator to convert the interference signal into a current for charging the stimulator; that is, the converter can convert the interference signal into a current for charging the stimulator. The converter of the stimulator can be mounted on the stimulator's PCB board. In some embodiments, the first part 511 can be electrically connected to the converter on the stimulator's PCB board via an extension wire.

[0097] The electrode wire 100 can be cylindrical in shape. An accommodating space 6 extending axially along the electrode wire 100 can be formed inside the electrode wire 100. The second part 512 can be disposed within the accommodating space 6, i.e., the second part 512 can be inserted into the accommodating space 6. The second part 512 can be electrically connected to the second transmission line 3112. The second transmission line 3112 can be electrically connected to the second part 512 by welding, for example, by laser welding or resistance welding. Of course, the second transmission line 3112 can also be electrically connected to the second part 512 by other methods, such as winding or clamping.

[0098] The present invention also provides a neurostimulation system, which may include a stimulator and an electrode lead 100 as described in any of the above claims. One end of the electrode lead 100 may be implanted in the patient's body, and at least a portion of the stimulation segment 1 of the electrode lead 100 may be implanted in the patient's body. The other end of the electrode lead 100 may be electrically connected to the stimulator, and the connection segment 2 of the electrode lead 100 may be electrically connected to the stimulator. That is, the consumable module 5 of the electrode lead 100 may be electrically connected to the stimulator. The stimulator may be a pulse generator, which transmits stimulation signals to the patient's affected area through the electrode lead 100, and the stimulation contact 11 of the stimulation segment 1 provides electrical stimulation to the patient's affected area.

[0099] The neurostimulation system may also include extension leads (not shown), through which the consumption module 5 of the electrode lead 100 can be electrically connected to the stimulator. In this application, the connection block 51 can be electrically connected to the stimulator via the extension lead, and the second transmission line 3112 can transmit the interference signal to the extension lead via the connection block 51. The extension lead can transmit the interference signal to the stimulator's PCB board. The stimulator's PCB board may have a ground terminal, and the first part 511 of the connection block 51 can be electrically connected to the ground terminal on the stimulator's PCB board via the extension lead. The stimulator's PCB board may also have a converter, which can convert the interference signal into current for charging the stimulator. The first part 511 of the connection block 51 can be electrically connected to the converter on the stimulator's PCB board via the extension lead.

[0100] One end of the extension wire can also be electrically connected to the connection contact 21 of the connection segment 2 of the electrode wire 100, and the other end of the extension wire can be electrically connected to the stimulator. The extension wire can transmit the stimulation signal of the stimulator to the connection contact 21 of the connection segment 2. The connection contact 21 of the connection segment 2 transmits the stimulation signal through the filter 4 to the stimulation contact 11 of the stimulation segment 1 via the first transmission line 3111. The stimulation contact 11 of the stimulation segment 1 provides electrical stimulation to the patient's affected area.

[0101] Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of the invention without departing from the principles and spirit of the invention, and all such changes should fall within the protection scope of the claims of the present invention.

Claims

1. An electrode wire, characterized in that, The device includes a stimulation segment for providing electrical stimulation, a connection segment electrically connected to the stimulator, and an intermediate segment connecting the stimulation segment and the connection segment. The stimulation segment includes a plurality of stimulation contacts and at least one filter, one end of which is electrically connected to at least one stimulation contact. The intermediate segment includes a plurality of core wires, each core wire including at least one first transmission line for transmitting stimulation signals and at least one second transmission line for transmitting interference signals. The connection segment includes a plurality of connection contacts and a consumption module. One end of the first transmission line is electrically connected to the connection contact of the connection segment, and the other end of the first transmission line is electrically connected to the filter. One end of the second transmission line is electrically connected to the consumption module, and the other end of the second transmission line is electrically connected to the filter.

2. The electrode wire according to claim 1, characterized in that, The filter has a first end and a second end disposed opposite to each other. The first end of the filter has a first contact and a second contact. The first contact is electrically connected to the first transmission line, and the second contact is electrically connected to the second transmission line. The second end of the filter has a third contact, and the third contact is electrically connected to the stimulation contact of the stimulation segment. The filter further includes at least one first internal circuit and at least one second internal circuit. The first contact and the third contact are electrically connected through the first internal circuit, and the first internal circuit is electrically connected to the second contact through the second internal circuit.

3. The electrode wire according to claim 2, characterized in that, The number of filters is one, the number of the first internal circuit and the number of the first contacts are the same as the number of the first transmission lines, the number of the second contacts is one, and the number of the third contacts is the same as the number of the stimulation contacts.

4. The electrode wire according to claim 3, characterized in that, When there are multiple first internal circuits and second internal circuits, the first internal circuits are independent of each other, one end of the second internal circuit is electrically connected to the first internal circuit in a one-to-one correspondence, and the other end of all the second internal circuits is electrically connected to the second contact.

5. The electrode wire according to claim 4, characterized in that, There are multiple first transmission lines and one second transmission line. The first transmission line is electrically connected to the first contact in a one-to-one correspondence, and the second transmission line is electrically connected to the second contact.

6. The electrode wire according to claim 4, characterized in that, There are multiple first transmission lines and multiple second transmission lines. Each first transmission line is electrically connected to a first contact in a one-to-one correspondence, and all second transmission lines are simultaneously electrically connected to the second contacts.

7. The electrode wire according to claim 2, characterized in that, The number of filters is multiple, and the number of filters is the same as the number of stimulation contacts. Each filter is electrically connected to a stimulation contact in a one-to-one correspondence. The number of filters is the same as the number of the first transmission lines, and the filters are electrically connected to the first transmission lines in a one-to-one correspondence.

8. The electrode wire according to claim 7, characterized in that, The filter includes a first internal circuit and a second internal circuit, one end of the second internal circuit being electrically connected to the first internal circuit, and the other end of the second internal circuit being electrically connected to the second contact.

9. The electrode wire according to claim 8, characterized in that, When the number of the first transmission lines and the number of the second transmission lines are the same, the first transmission lines are electrically connected to the first contacts in a one-to-one correspondence, and the second transmission lines are electrically connected to the second contacts in a one-to-one correspondence.

10. The electrode wire according to claim 8, characterized in that, When there are multiple first transmission lines and one second transmission line, the first transmission line is electrically connected to the first contact in a one-to-one correspondence, and all second contacts are electrically connected to the second transmission line.

11. The electrode wire according to claim 2, characterized in that, The filter includes one or more inductors connected in series in a first internal circuit between the first contact and the third contact, such that the inductor is connected in series with the first transmission line; and / or The filter includes one or more capacitors, which are disposed in the second internal circuit. The capacitors are connected in parallel with the first transmission line, and in series with the second transmission line; and / or... The filter includes one or more diodes, which are disposed on the second internal circuit and between the capacitor and the first transmission line.

12. The electrode wire according to claim 1, characterized in that, The consumption module is a connection block, which is used to electrically connect the second transmission line to the stimulator; or... The consumption module is a load, which is used to convert the interference signal into heat.

13. The electrode wire according to claim 12, characterized in that, When the consumption module is a connection block, the connection block includes a first part and a second part that are connected to each other. The first part is disposed at one end of the connection segment away from the middle segment. The first part is used to be electrically connected to the ground terminal of the stimulator, or the first part is used to be electrically connected to the converter of the stimulator so that the interference signal is converted into a current for charging the stimulator. The electrode wire is generally cylindrical, and an accommodating space is formed inside the electrode wire extending along the axial direction of the electrode wire. The second part is disposed in the accommodating space and is electrically connected to the second transmission line.

14. The electrode wire according to claim 13, characterized in that, The second transmission line is electrically connected to the second part by welding.

15. The electrode wire according to claim 1, characterized in that, Multiple core wires are twisted together to form a conductor wire. Each core wire includes a conductor and an insulating layer, with the insulating layer covering the conductor. Each core wire includes at least one conductor. The guidewire also includes an outer sheath layer, which covers the core wire.

16. The electrode wire according to claim 15, characterized in that, The guide wire is spirally wound along the axial direction of the electrode wire; When the number of guidewires is multiple strands, the multiple strands of guidewires are wound in a spiral shape with the same spiral direction.

17. A neural stimulation system, characterized in that, include: Stimulator; The electrode lead as described in any one of claims 1 to 16, wherein one end of the electrode lead is implanted in the patient's body and the other end of the electrode lead is electrically connected to the stimulator.

18. The implantable medical device according to claim 17, characterized in that, The electrode lead consumption module is electrically connected to the stimulator; or, The neurostimulation system also includes extension leads, and the electrode lead consumption module is electrically connected to the stimulator through the extension leads.

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