Preparation process and device of sealing tape

Abstract

This application discloses a process and apparatus for preparing sealing tape, relating to the field of tape preparation technology. The steps include: S1: outputting the base film of the tape from the unwinding device to the first coating head device for coating a first layer of adhesive; S2: blowing air onto the first layer of adhesive with a fan to form a fine water ripple pattern; S3: baking the first layer of adhesive in an oven to set the fine water ripple pattern; S4: coating a second layer of adhesive with a second coating head device, and pressing it with an anilox roller on the second coating head device to form an orange peel texture; S5: setting the orange peel texture with a UV curing device; S6: winding the tape using a winding device.

Description

Technical Field

[0001] This application belongs to the field of tape preparation technology, specifically relating to a preparation process and apparatus for sealing tape. Background Technology

[0002] Traditionally, pathological slides are mounted using coverslips and neutral resin, but now some use mounting tape instead of coverslips.

[0003] However, current adhesive tapes are all smooth and lack texture. This can easily lead to insufficient initial adhesion, resulting in edge lifting or delamination, especially in low-temperature or humid environments where failure is exacerbated. Because smooth surfaces have low interfacial tension, the contact area between the adhesive layer and the adhered material is small, and the intermolecular forces are weak, easily leading to adhesion and peeling defects. Furthermore, the lack of texture can cause the tape to shift and deviate after application. It also prevents air permeability and heat dissipation, making it prone to air bubble formation. Since the smooth surface lacks pores, air bubbles are difficult to expel after the adhesive layer cures. If air bubbles are not expelled from pathological tissue, they can compress surrounding tissue, causing disordered cell arrangement, tissue fissures, or breaks. The tissue around the air bubbles may also shrink, easily misdiagnosed as necrosis, infarction, or fissure-like lesions. The air bubbles themselves can be easily misdiagnosed as glandular cavities, vascular cavities, or vacuolar degeneration. Air bubbles can also block sufficient contact between the staining solution and the tissue, causing local staining to be too light or too dark, detachment, or a cloudy background. After mounting, the air inside the air bubbles oxidizes, causing the adhesive layer to yellow and produce refraction, affecting the clarity of microscopic observation. Furthermore, large air bubbles can directly obscure the lesion area, leading to missed diagnoses; when small air bubbles are densely distributed, they can divide the tissue, making it impossible for pathologists to observe the complete tissue morphology; moreover, air bubbles can damage the sealing properties of the mounting adhesive, allowing air to enter and accelerating tissue oxidation, stain fading, and antigen degradation; when humidity changes, the moisture inside the air bubbles will condense, leading to detachment of the slide, mold spots, and cracking of the adhesive layer, affecting the final test results. Summary of the Invention

[0004] This application provides a process and apparatus for preparing sealing tape to solve the above-mentioned technical problems: the tape has no texture, insufficient initial adhesion, and is prone to edge lifting or delamination; the contact area between the tape layer and the adhered object is small, and the intermolecular forces are weak, which easily leads to adhesion and peeling defects; it cannot achieve air permeability and heat dissipation, and it is also prone to generating air bubbles. Because the smooth surface has no pores, the air bubbles are difficult to expel after the adhesive layer has cured. If the air bubbles are not expelled, they will cause compression of the surrounding tissue, resulting in cell arrangement disorder, tissue cracks or breaks.

[0005] The technical solution adopted in this application is as follows: A process for preparing sealing tape, comprising the following steps: S1: The base film of the tape is output from the unwinding device to the first coating head device for coating the first layer of adhesive; S2: The fan blows air onto the first layer of colloid, causing the first layer of colloid to form fine water ripples; S3: The first layer of colloid is baked in an oven to set the fine water ripples; S4: The second layer of colloid is coated by the second coating head device and pressed by the anilox roller on the second coating head device, so that the second layer of colloid forms an orange peel texture. S5: The orange peel texture is fixed by a UV curing device; S6: The tape is wound up using a winding device.

[0006] The sealing tape of this application is specifically designed for mounting pathological tissue slides. Traditionally, pathological slides are sealed with coverslips and neutral resin; this application replaces these with sealing tape, and the tape is textured, giving the sealing side a double-layered texture. This significantly improves adhesion stability and functionality, further enhancing the tape's bonding performance and stability. Initial tack and sustained adhesion are strengthened, as are resistance to edge lifting, delamination, and slippage. Furthermore, its strength withstands lower temperatures and humid environments. Because of the texture, the tape provides better sealing during encapsulation, increased friction prevents misalignment, and air bubbles are easily contained within the texture. The tape is discharged under the guidance of the adhesive, leaving no residue. Furthermore, the textured surface area of ​​the tape increases, resulting in excellent breathability and heat dissipation. It also reduces the area exposed to direct ultraviolet radiation, delaying adhesive aging. The tape's peel strength is improved and made more uniform, with strong positioning and guidance. It also enhances auxiliary mounting and strengthens the tape's self-guiding adhesion ability, significantly reducing human interference. After manual alignment on one side, the tape achieves positioning and guidance under the action of the textured surface. It can quickly fuse with reagents on the slide and instantly fuse with the adhesive on the sealing tape. It not only possesses the tackiness of laser adhesive but also achieves self-guiding positioning, enabling rapid bonding and significantly improving mounting yield.

[0007] In a preferred embodiment, before S1, a first adhesive is filled into the first material tank of the first coating head device, and a surfactant is added to the first adhesive to make the viscosity range 3500-4500 cps; a second adhesive is filled into the second material tank of the second coating head device, and a photoinitiator is added to the second adhesive to make the viscosity range 1500-2500 cps.

[0008] In the technical solution of this application, a first adhesive is added to the first coating head device. The addition of a surfactant to the first adhesive reduces surface tension, improves wetting and spreading properties, and assists in degassing and defoaming, making it particularly suitable for reducing residual bubbles when coating textured substrates. The high-viscosity formulation also helps maintain coating thickness uniformity, preventing insufficient texture filling or sagging. A second adhesive is added to the second trough of the second coating head device, and a photoinitiator is added to the second adhesive. Corresponding to the UV curing process, the low-viscosity formulation has good fluidity and fast penetration, allowing for rapid filling of texture gaps or thin coating application. The photoinitiator ensures rapid curing under UV irradiation, improving production efficiency. The low viscosity also facilitates interfacial bonding with the high-viscosity coating, preventing delamination.

[0009] This application achieves functional layering by designing a combination of two adhesives, two additives, and two viscosities: the first coating focuses on adhesive strength, wetting, and defoaming, while the second coating focuses on rapid curing, surface properties, and functionality.

[0010] In a preferred embodiment, the fan is positioned 20-30 cm above the first coating head device, the fan's tilt angle α is in the range of 40-50°, and the fan is provided with a flat air outlet facing the base film, with a wind speed of 40-55 Hz, so that the fine water ripples are distributed in a wave-like pattern along the transverse direction of the tape.

[0011] In the technical solution of this application, the height range of 20-30 cm above the first coating head can prevent the airflow from directly impacting the uncured adhesive layer, causing the coating to drip or shift, while ensuring that the airflow effectively acts on the adhesive layer surface; the tilt angle of 40-50° is precisely aimed at the base film surface, which is neither too small an angle causing the airflow to blow along the coating direction, nor too large an angle causing the airflow to impact vertically, which is just right to meet the molding requirements of horizontal water ripples; the flat air outlet can form a uniform and narrow laminar airflow, avoiding the turbulence of the circular air outlet that causes uneven ripple thickness; the directional design ensures that the airflow is concentrated on the adhesive layer surface, rather than spreading to the surrounding environment, causing energy waste or dust disturbance; the wind force of 40-55 Hz can precisely control the airflow intensity, which can form fine wavy water ripples on the surface of high viscosity adhesive layer without destroying the thickness uniformity of adhesive layer.

[0012] The first coating head is responsible for applying the high-viscosity adhesive. At this stage, the adhesive layer is not yet cured, which is the golden window for texture formation. The immediate action of the blower enables continuous operation of "coating-texturing," eliminating the need for additional embossing rollers and other equipment, thus reducing equipment costs and process complexity. The fine, transverse water ripples serve as the micro-texture of the sealing tape, enhancing the adhesion strength between the tape and the substrate, assisting in degassing and defoaming, and providing air escape channels through the ripple gaps. Furthermore, it enhances the surface's printability, perfectly matching the needs of high-precision applications such as pathology slide sealing.

[0013] In a preferred embodiment, the oven has at least three sections, wherein the temperature of the first section reaches at least 70°C, the temperature of the second section reaches at least 100°C, and the temperature of the third section reaches at least 120°C.

[0014] In the technical solution of this application, the first section (≥70℃): low-temperature pre-baking, slowly evaporates residual solvents or moisture in the adhesive layer, avoiding rapid heating that could lead to bubbles or pinholes; simultaneously, it initially fixes the shape of the adhesive layer, preventing texture deformation in subsequent high-temperature stages. The second section (≥100℃): medium-temperature main baking, accelerates the cross-linking reaction of the adhesive layer, improving bonding strength and holding power; this temperature range is suitable for the stability of additives such as surfactants and photoinitiators, preventing additive decomposition and failure. The third section (≥120℃): high-temperature final baking, thoroughly removes residual solvents, completes the full curing of the adhesive layer, and ensures the stability of the tape in subsequent processing and high- or low-temperature cycling. It achieves independent temperature control in different zones, avoiding differences in adhesive layer curing caused by uneven temperatures in individual oven sections; the segmented design adapts to the long-process requirements of continuous coating production lines, and by extending the length of each oven section or adjusting the conveyor belt speed, the residence time of the adhesive layer in different temperature sections can be precisely controlled, achieving continuous operation of "coating-texture forming-gradient curing," significantly improving mass production efficiency. It is highly compatible with the high viscosity adhesive of the first coating head and the fine water ripple texture formed by the fan: gradient heating can avoid the high temperature directly impacting the uncured water ripple adhesive layer, preventing the texture from collapsing or sagging; at the same time, the fully cured adhesive layer can serve as a stable base, providing good interfacial adhesion for the second coating head to apply low viscosity adhesive (1500-2500 cps), avoiding delamination.

[0015] In one preferred embodiment, fine water ripples form crest regions and trough regions on the first layer of colloid, with the height of the crest region being 15-25 μm and the height of the trough region being 5-15 μm.

[0016] In the technical solution of this application, a crest region and a trough region are formed on the first layer of colloid. The intervals are non-overlapping and have clear boundaries, which not only ensures the "fine" characteristics of the fine water ripples, but also forms a stable microscopic height difference. The interval design is compatible with the tolerance of coating thickness fluctuations and fan airflow parameter fine-tuning during production, avoiding the yield reduction caused by single value settings. The height difference is the key to forming effective microscopic anchor points and exhaust channels. It can not only enable the colloid layer to form a mechanical interlock with the adhered object, improving the bonding strength and anti-slip properties, but also quickly expel air through the gaps between the troughs, solving the problem of air bubble residue during sealing. The fine, horizontally distributed water ripples provide the main bonding contact area at the crests and serve as venting or adhesive storage channels at the troughs, thus balancing the two core functions of bonding stability and defoaming. The 15-25μm crests and 5-15μm troughs are highly compatible with the high-viscosity adhesive (3500-4500 cps) of the first coating head and the fan-textured molding process, preventing sagging due to excessive adhesive layer thickness and unclear texture due to excessively thin layer thickness. At the same time, it provides a stable substrate interface for the subsequent coating of the low-viscosity adhesive (1500-2500 cps) of the second coating head, avoiding delamination.

[0017] As a preferred embodiment, the orange peel texture can be applied over the fine water ripple pattern and form a height of 3-5 μm.

[0018] In the technical solution of this application, the tiny protrusions of the orange peel texture can reduce the surface tension of the tape, allowing for more thorough contact between the adhesive layer and the substrate during sealing, reducing interfacial gaps, and improving surface wetting and spreadability. The micro-uneven surface structure increases the friction during mounting, preventing tape displacement and deviation, and enhancing anti-slip and positioning capabilities. The orange peel texture is positioned above the fine water ripples as a second layer of adhesive. The fine water ripples in the lower layer can store sufficient xylene at the troughs to prevent drying, while the adhesive layer is relatively thicker at the crests, ensuring that the undissolved adhesive layer adheres firmly to the slide, solving the problem of poor adhesion. To prevent drying at the crests, the upper texture plays a crucial role; the xylene stored in the texture and the xylene that penetrates laterally at the troughs successfully prevents drying.

[0019] This application also relates to an apparatus for preparing sealing tape, based on the above-described process for preparing sealing tape, comprising: An unwinding device for winding the base film of the adhesive tape; The first coating head device is used to receive the base film output from the unwinding device and coat one side of the base film with a first layer of colloid. A blower is used to blow air toward the first layer of colloid, forming fine water ripples in the first layer of colloid. An oven is used to blow air onto the tape passing through the fan, curing the fine water ripples into a solid shape. The second coating head device is used to coat the tape with a second layer of adhesive and form an orange peel texture; A UV curing device is used to cure and shape the orange peel texture. A winding device is used to collect the tape.

[0020] The tape manufacturing apparatus of this application realizes a closed-loop process from base film to finished product, enabling continuous mass production. The process is complete and tightly connected, from unwinding to first coating, first colloid, gradient curing, second colloid, second colloid curing, and rewinding—a complete chain without process interruptions. The outputs and inputs of each device are directly connected, ensuring stable tape posture between processes. This avoids problems such as adhesive layer damage, texture deformation, and uneven tension caused by intermediate transfers. Continuous production significantly improves production efficiency, reduces downtime and debugging time associated with intermittent production, and ensures stable connection between processes, minimizing defects such as adhesive layer bubbles, texture disorder, and coating delamination. This design significantly improves mass production yield. Each unit is an independent module, allowing for flexible addition, removal, or replacement of modules according to different product needs. The first coating head unit achieves uniform coating of high-viscosity adhesive, using a fan to create a fine water ripple pattern on the first layer of adhesive. A three-stage oven then performs gradient curing on the fine water ripple pattern: low-temperature baking slowly evaporates residual solvents in the adhesive layer, medium-temperature baking accelerates the cross-linking reaction of the adhesive layer, and high-temperature baking completely removes residual solvents, completing the full curing of the adhesive layer. The second coating head unit achieves quantitative coating of low-viscosity adhesive, followed by rapid curing of the orange peel texture using a UV curing device. Finally, the tape is collected and organized by a winding device.

[0021] In a preferred embodiment, the first coating head device includes a first base, a coating roller, and a first guide roller; a first material trough is provided on the first base; the coating roller and the first guide roller are rotatably connected to the first base; a portion of the coating roller is immersed in the first material trough, and the adhesive tape is wound onto the coating roller to achieve the coating of the first layer of adhesive, and then output from between the coating roller and the first guide roller.

[0022] In the technical solution of this application, by precisely adjusting the base adhesive amount of the adhesive layer through controlling the impregnation depth, and in conjunction with the linkage control of the coating roller speed and the tape speed, a stable and uniform coating of high-viscosity adhesive (3500-4500 cps) can be achieved, avoiding excessively thick adhesive layers that cause sagging or excessively thin layers that expose the substrate. The coating roller and the first guide roller form a roller gap clamping and guiding structure, which can not only scrape off excess adhesive from the tape surface and further calibrate the adhesive layer thickness, but also provide traction and shaping for the coated tape, preventing the tape from shifting or wrinkling due to uneven tension after coating, thus providing a flat and stable adhesive base for the subsequent fan texture forming process.

[0023] In a preferred embodiment, the second coating head device includes a second base, an anilox roller, and a second guide roller; a second material trough is provided on the second base, and the anilox roller and the second guide roller are rotatably connected to the second base; a portion of the anilox roller is immersed in the second material trough, and the tape is wound onto the anilox roller to achieve the coating of the second layer of adhesive, and then output from between the anilox roller and the second guide roller.

[0024] In the technical solution of this application, the anilox roller is partially immersed in the second material tank. With the linkage between the rotation speed and the tape speed, the adhesive can be stably transferred to the surface of the tape. This avoids covering the venting channels in the troughs and can uniformly form the upper layer of orange peel texture, achieving functional complementarity between the two layers of texture. The anilox roller and the second guide roller are rotatably connected and form a roller gap clamping and output structure: on the one hand, it can scrape off excess adhesive and further calibrate the coating thickness; on the other hand, it can pull the tape to prevent deviation and wrinkling caused by uneven tension after adhesive application, ensuring the stability of subsequent curing and processing.

[0025] In a preferred embodiment, an orange peel texture is formed on the outer surface of the anilox roller, with a mesh count of 70-90 and a processing depth of 90-110μm.

[0026] In the technical solution of this application, an anilox roller replaces an ordinary coating roller. The cell structure on its surface can accurately measure and transfer low-viscosity adhesive (1500-2500 cps), solving the pain points of low-viscosity adhesive being prone to sagging and difficult to control the coating amount. The volume and density of the cells can match the target coating height of 3-5μm orange peel texture, realizing quantitative supply of adhesive and ensuring the consistency of coating thickness.

[0027] Due to the adoption of the above technical solution, the beneficial effects achieved by this application are as follows: 1. The sealing tape of this application is specifically designed for mounting pathological tissue slides. Traditionally, pathological slides are mounted using coverslips and neutral resin; this application replaces these with sealing tape, and the tape is textured, giving the side used for mounting a double-layered texture. This significantly improves adhesion stability and functionality, further enhancing the tape's bonding performance and stability. Initial tack and sustained adhesion are strengthened, as are resistance to edge lifting, delamination, and slippage. Furthermore, its resistance to low temperatures or humid environments is improved. Because the tape has a texture, the sealing performance is better during the sealing process, increased friction prevents misalignment, and air bubbles are easily contained within the texture. Under the guidance of the adhesive, the tape is discharged without leaving any residue. Furthermore, the textured surface area of ​​the tape increases, resulting in excellent breathability and heat dissipation. It also reduces the area exposed to direct ultraviolet radiation, delaying adhesive aging. The tape improves peel strength and makes it more uniform, providing strong positioning guidance and enhancing auxiliary mounting. It strengthens the tape's self-guiding adhesion ability, significantly reducing human interference. After manual alignment on one side, the tape achieves positioning guidance under the influence of the textured surface. It can quickly fuse with reagents on the slide and instantly fuse with the adhesive on the sealing tape. It not only possesses the adhesion of laser adhesive but also achieves self-guiding positioning, enabling rapid bonding and significantly improving mounting yield.

[0028] 2. The tape preparation apparatus of this application realizes a closed-loop process from base film to finished product, enabling continuous mass production. The process is complete and tightly connected, from unwinding to first coating, first colloid, gradient curing, second colloid, second colloid curing, and rewinding—a complete chain without process interruptions. The outputs and inputs of each device are directly connected, ensuring stable tape posture between processes. This avoids problems such as adhesive layer damage, texture deformation, and uneven tension caused by intermediate transfers. Continuous production significantly improves production efficiency, reduces downtime and debugging time associated with intermittent production, and ensures stable connection between processes, minimizing adhesive layer bubbles, texture disorder, and coating delamination. The defects are significantly improved, resulting in a higher mass production yield. Each unit is an independent module, allowing for flexible addition, removal, or replacement of modules according to different product needs. The first coating head unit achieves uniform coating of high-viscosity adhesive, using a fan to create a fine water ripple pattern on the first layer of adhesive. A three-stage oven then performs gradient curing on the fine water ripple pattern: low-temperature baking slowly evaporates residual solvents in the adhesive layer, medium-temperature baking accelerates the cross-linking reaction of the adhesive layer, and high-temperature baking completely removes residual solvents, completing the full curing of the adhesive layer. The second coating head unit achieves quantitative coating of low-viscosity adhesive, followed by rapid curing of the orange peel texture using a UV curing device. Finally, the tape is collected and organized by a winding device. Attached Figure Description

[0029] The accompanying drawings, which are included to provide a further understanding of this application and form part of this application, illustrate exemplary embodiments and are used to explain this application, but do not constitute an undue limitation of this application. In the drawings: Figure 1 This is a schematic diagram of a sealing tape preparation apparatus according to one embodiment of this application; Figure 2 This is a schematic diagram of the structure of the second coating head device of a sealing tape preparation apparatus according to one embodiment of this application; Figure 3 This is a schematic diagram of the structure of an anilox roller in a sealing tape preparation apparatus according to one embodiment of this application; Figure 4 This is a schematic diagram of the structure of an anilox roller in a sealing tape preparation apparatus according to another embodiment of this application; Figure 5 This is a flowchart illustrating the preparation process of a sealing tape according to one embodiment of this application; In the picture, 1. Unwinding device; 2. First coating head device; 3. Fan; 4. Air outlet; 5. Drying oven; 6. Second coating head device; 61. Second base; 62. Second guide roller; 7. Anilox roller; 8. UV curing unit; 9. Rewinding unit; 10. Coating roller; a- The tilt angle of the fan. Detailed Implementation

[0030] To more clearly illustrate the overall concept of this application, a detailed explanation is provided below with reference to the accompanying drawings.

[0031] Many specific details are set forth in the following description in order to provide a full understanding of this application. However, this application may also be implemented in other ways different from those described herein. Therefore, the scope of protection of this application is not limited to the specific embodiments disclosed below.

[0032] Furthermore, it should be understood in the description of this application that the terms "top", "bottom", "inner", "outer", "axial", "radial", "circumferential", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention.

[0033] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection, an electrical connection, or a communication connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0034] In this application, unless otherwise expressly specified and limited, the "above" or "below" of the second feature can mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediate medium. In the description of this specification, references to terms such as "implementation," "example," "a particular embodiment," "example," or "specific example," etc., indicate that the specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of this application. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described can be combined in any suitable manner in one or more embodiments or examples.

[0035] Example 1 A manufacturing process for sealing tape, such as Figure 5 As shown, the steps include: S1: The base film of the tape is output from the unwinding device 1 to the first coating head device 2 for coating the first layer of adhesive; S2: The blower 3 blows air onto the first layer of colloid, causing the first layer of colloid to form fine water ripples; S3: The first layer of colloid is baked in oven 5 to set the fine water ripples; S4: The second layer of colloid is coated by the second coating head device 6 and pressed by the anilox roller 7 on the second coating head device 6, so that the second layer of colloid forms an orange peel texture. S5: The orange peel texture is fixed by UV curing device 8; S6: The tape is wound up using the winding device 9.

[0036] The sealing tape of this application is specifically designed for mounting pathological tissue slides. Traditionally, pathological slides are sealed with coverslips and neutral resin; this application replaces these with sealing tape, and the tape is textured, giving the sealing side a double-layered texture. This significantly improves adhesion stability and functionality, further enhancing the tape's bonding performance and stability. Initial tack and sustained adhesion are strengthened, as are resistance to edge lifting, delamination, and slippage. Furthermore, its strength withstands lower temperatures and humid environments. Because of the texture, the tape provides better sealing during encapsulation, increased friction prevents misalignment, and air bubbles are easily contained within the texture. The tape is discharged under the guidance of the adhesive, leaving no residue. Furthermore, the textured surface area of ​​the tape increases, resulting in excellent breathability and heat dissipation. It also reduces the area exposed to direct ultraviolet radiation, delaying adhesive aging. The tape's peel strength is improved and made more uniform, with strong positioning and guidance. It also enhances auxiliary mounting and strengthens the tape's self-guiding adhesion ability, significantly reducing human interference. After manual alignment on one side, the tape achieves positioning and guidance under the action of the textured surface. It can quickly fuse with reagents on the slide and instantly fuse with the adhesive on the sealing tape. It not only possesses the tackiness of laser adhesive but also achieves self-guiding positioning, enabling rapid bonding and significantly improving mounting yield.

[0037] In a preferred embodiment, before S1, the first adhesive is filled into the first material tank of the first coating head device 2, and a surfactant is added to the first adhesive to make the viscosity range 3500-4500 cps; the second adhesive is filled into the second material tank of the second coating head device 6, and a photoinitiator is added to the second adhesive to make the viscosity range 1500-2500 cps.

[0038] In the technical solution of this application, a first adhesive is added to the first coating head device 2. The addition of a surfactant to the first adhesive reduces surface tension, improves wetting and spreading properties, and assists in degassing and defoaming, making it particularly suitable for reducing residual bubbles when coating textured substrates. The high-viscosity formulation also helps maintain coating thickness uniformity, preventing insufficient texture filling or sagging. A second adhesive is added to the second feed tank of the second coating head device 6, and a photoinitiator is added to the second adhesive. Corresponding to the UV curing process, the low-viscosity formulation has good fluidity and fast penetration, allowing for rapid filling of texture gaps or thin coating application. The photoinitiator ensures rapid curing under UV irradiation, improving production efficiency. The low viscosity also facilitates interfacial bonding with high-viscosity coatings, preventing delamination.

[0039] This application achieves functional layering by designing a combination of two adhesives, two additives, and two viscosities: the first coating focuses on adhesive strength, wetting, and defoaming, while the second coating focuses on rapid curing, surface properties, and functionality.

[0040] Further, in step S1: the base film of the tape is output from the unwinding device 1 to the first coating head device 2 for coating the first layer of adhesive; firstly, the first adhesive is added to the first material tank of the first coating head device 2, and the coating is smoothed with a scraper, with a coating speed of 1m / min selected.

[0041] Further, in step S2: the blower 3 blows air onto the first layer of adhesive, causing the first layer of adhesive to form fine water ripples; the purpose of the fine water ripples in the first layer of adhesive is to create the effect of uneven thickness; where the longitudinal direction refers to the length direction of the tape, the fine water ripples are transverse, the width of the blower 3's air outlet 4 is not less than the width of the adhesive's base film, ensuring that the width of the air outlet 4 is wider than the base film, ensuring that the tape completely covers the fine water ripples along the width direction.

[0042] The method described in this application effectively prevents drying. The first and second layers of colloid form a composite texture on the base film. Orange peel texture alone cannot truly prevent drying; only sufficient xylene stored within the texture can prevent it. However, if there is only one texture layer, and the texture is too deep, the tape will cure slowly after sealing, resulting in poor adhesion. The fine water ripple texture stores sufficient xylene at the troughs, solving the drying problem, while the relatively thicker adhesive layer at the crests allows the undissolved adhesive layer to adhere firmly to the slide, solving the problem of poor adhesion. To prevent drying at the crests, the upper texture layer plays a crucial role; the xylene stored in the texture and the xylene that penetrates laterally at the troughs successfully prevents drying. Furthermore, this method effectively prevents the formation of sealing bubbles. The bottom water ripple texture and the upper orange peel texture work together to remove bubbles. Moreover, this method effectively reduces adhesion between the base film and the adhesive surface. Because of the textured surface of the adhesive, the contact area between the adhesive layer and the next layer of base film is reduced after winding, which can avoid the adhesion between the base film and the adhesive surface caused by external pressure during transportation or storage. Moreover, this method can greatly reduce costs when forming the fine water ripples of the first layer. If an adhesive layer with a thickness of 20µm at the crest and 10µm at the trough is directly coated with a coating roller, the design difficulty and processing precision requirements of the coating roller are extremely high.

[0043] In addition, it should be noted that the sealing tape of this application is mainly used for sealing pathological slides, which contain tissue slices with a thickness of 3-10 μm.

[0044] The bubble-removing principle of the sealing tape in this application is as follows: the finished sealing tape is non-adhesive. During sealing, a reagent, such as xylene, needs to be dropped onto the slide containing the tissue. Xylene can instantly fuse with the second layer of adhesive on the sealing tape, activating the adhesiveness of the second layer, allowing the tape to quickly cover the slide. The sealing process must be carried out on a sealing device. This process involves a pressure roller rolling the tape from the tail end to the head end of the slide. If the sealing tape has no texture, air bubbles are easily formed in the uneven areas of the tissue during sealing. However, the texture of the tape creates a discontinuous contact between the adhesive layer and the tissue, reducing the space for air retention. The texture can also effectively guide air bubbles to escape along the texture, preventing air bubble accumulation.

[0045] In a preferred embodiment, the blower 3 is positioned 20-30 cm above the first coating head device 2, with an inclination angle of 40-50°. The blower 3 is also provided with a flat air outlet 4 facing the base film, and the airflow is 40-55 Hz, so that the fine water ripples are distributed in a wave-like pattern along the transverse direction of the tape.

[0046] In the technical solution of this application, the height range of 20-30 cm above the first coating head can prevent the airflow of the fan 3 from directly impacting the uncured adhesive layer, causing the coating to drip or shift, while ensuring that the airflow effectively acts on the adhesive layer surface; the tilt angle α of the fan 3 is in the range of 40-50°, which is precisely pointed to the base film surface, so that the airflow will not blow along the coating direction due to the tilt angle being too small, nor will the airflow impact vertically due to the tilt angle being too large, which is just right to meet the molding requirements of the horizontal water ripples; the flat air outlet can form a uniform and narrow laminar airflow, avoiding the turbulence of the circular air outlet that causes uneven ripple thickness; the directional design ensures that the airflow is concentrated on the adhesive layer surface, rather than spreading to the surrounding environment and causing energy waste or dust disturbance; the wind force is 40-55 Hz, which can precisely control the airflow intensity, so as to form a fine wave-like water ripple on the surface of the high viscosity adhesive layer without destroying the thickness uniformity of the adhesive layer.

[0047] The first coating head is responsible for applying the high-viscosity adhesive. At this stage, the adhesive layer is not yet cured, which is the golden window for texture formation. The immediate action of fan 3 enables continuous operation of "coating-texturing," eliminating the need for additional embossing rollers and other equipment, thus reducing equipment costs and process complexity. The fine, transverse water ripples serve as the micro-texture of the sealing tape, enhancing the adhesion strength between the tape and the substrate, assisting in degassing and defoaming, and providing air escape channels through the ripple gaps. Simultaneously, it enhances the surface's printability, perfectly matching the needs of high-precision scenarios such as pathology slide sealing.

[0048] In a preferred embodiment, the oven 5 has at least three sections, wherein the temperature of the first section reaches at least 70°C, the temperature of the second section reaches at least 100°C, and the temperature of the third section reaches at least 120°C.

[0049] In the technical solution of this application, the first section (≥70℃): low-temperature pre-baking, slowly evaporates residual solvents or moisture in the adhesive layer, avoiding rapid heating that could lead to bubbles or pinholes; simultaneously, it initially fixes the shape of the adhesive layer, preventing texture deformation in subsequent high-temperature stages. The second section (≥100℃): medium-temperature main baking, accelerates the cross-linking reaction of the adhesive layer, improving bonding strength and holding power; this temperature range is suitable for the stability of additives such as surfactants and photoinitiators, preventing additive decomposition and failure. The third section (≥120℃): high-temperature final baking, thoroughly removes residual solvents, completes the full curing of the adhesive layer, and ensures the stability of the tape in subsequent processing and high- or low-temperature cycling. It achieves independent temperature control in different zones, avoiding differences in adhesive layer curing caused by uneven temperatures in a single oven section 5; the segmented design adapts to the long-process requirements of continuous coating production lines, and by extending the length of each oven section 5 or adjusting the conveyor belt speed, the residence time of the adhesive layer in different temperature ranges can be precisely controlled, achieving continuous operation of "coating-texture forming-gradient curing," significantly improving mass production efficiency. The high viscosity adhesive of the first coating head and the fine water ripple texture formed by the fan 3 are highly compatible: the gradient heating can avoid the high temperature directly impacting the uncured water ripple adhesive layer, preventing the texture from collapsing or sagging; at the same time, the fully cured adhesive layer can serve as a stable base, providing good interfacial adhesion for the second coating head to apply low viscosity adhesive (1500-2500 cps), avoiding delamination.

[0050] In one preferred embodiment, fine water ripples form crest regions and trough regions on the first layer of colloid, with the height of the crest region being 15-25 μm and the height of the trough region being 5-15 μm.

[0051] In the technical solution of this application, a crest region and a trough region are formed on the first layer of colloid. The intervals are non-overlapping and have clear boundaries, which not only ensures the "fine" characteristics of the fine water ripples, but also forms a stable microscopic height difference. The interval design is compatible with the tolerance of coating thickness fluctuations and fan airflow parameter fine-tuning during production, avoiding the yield reduction caused by single value settings. The height difference is the key to forming effective microscopic anchor points and exhaust channels. It can not only enable the colloid layer to form a mechanical interlock with the adhered object, improving the bonding strength and anti-slip properties, but also quickly expel air through the gaps between the troughs, solving the problem of air bubble residue during sealing. The fine, horizontally distributed water ripples provide the main bonding contact area at the crests and serve as venting or adhesive storage channels at the troughs, thus balancing the two core functions of bonding stability and defoaming. The 15-25μm crests and 5-15μm troughs are highly compatible with the high-viscosity adhesive (3500-4500 cps) of the first coating head and the texture molding process of the blower 3, preventing sagging due to excessive adhesive layer thickness and unclear texture due to excessively thin layer thickness. At the same time, it provides a stable substrate interface for the subsequent coating of the low-viscosity adhesive (1500-2500 cps) of the second coating head, avoiding delamination.

[0052] As a preferred embodiment, the orange peel texture can be applied over the fine water ripple pattern and form a height of 3-5 μm.

[0053] In the technical solution of this application, the tiny protrusions of the orange peel texture can reduce the surface tension of the tape, allowing for more thorough contact between the adhesive layer and the substrate during sealing, reducing interfacial gaps, and improving surface wetting and spreadability. The micro-uneven surface structure increases the friction during mounting, preventing tape displacement and deviation, and enhancing anti-slip and positioning capabilities. The orange peel texture is positioned above the fine water ripples as a second layer of adhesive. The fine water ripples in the lower layer can store sufficient xylene at the troughs to prevent drying, while the adhesive layer is relatively thicker at the crests, ensuring that the undissolved adhesive layer adheres firmly to the slide, solving the problem of poor adhesion. To prevent drying at the crests, the upper texture plays a crucial role; the xylene stored in the texture and the xylene that penetrates laterally at the troughs successfully prevents drying.

[0054] Example 2 This application also relates to an apparatus for preparing sealing tape, such as... Figure 1-4 As shown, the manufacturing process of a sealing tape based on the above includes: Unwinding device 1, used for winding the base film of the adhesive tape; The first coating head device 2 is used to receive the base film output from the unwinding device 1 and coat one side of the base film with a first layer of colloid. Fan 3 is used to blow air toward the first layer of colloid, forming fine water ripples in the first layer of colloid; Oven 5 is used to blow air onto the tape passing through fan 3 to solidify the fine water ripple pattern. The second coating head device 6 is used to coat the tape with a second layer of adhesive and form an orange peel texture. UV curing device 8 is used to cure and shape the orange peel texture; The winding device 9 is used to collect the tape.

[0055] The tape manufacturing apparatus of this application realizes a closed-loop process from base film to finished product, enabling continuous mass production. The process is complete and tightly connected, from unwinding to first coating, first colloid, gradient curing, second colloid, second colloid curing, and rewinding—a complete chain without process interruptions. The outputs and inputs of each device are directly connected, ensuring stable tape posture between processes. This avoids problems such as adhesive layer damage, texture deformation, and uneven tension caused by intermediate transfers. Continuous production significantly improves production efficiency, reduces downtime and debugging time associated with intermittent production, and ensures stable connection between processes, reducing defects such as adhesive layer bubbles, texture disorder, and coating delamination. This significantly improves mass production yield. Each unit is an independent module, allowing for flexible addition, reduction, or replacement of modules according to different product needs. The first coating head unit 2 achieves uniform coating of high-viscosity adhesive. The fan 3 forms a fine water ripple pattern on the first layer of adhesive. The three-stage oven 5 performs gradient curing on the fine water ripple pattern. Low-temperature baking slowly evaporates the residual solvent in the adhesive layer, medium-temperature baking accelerates the cross-linking reaction of the adhesive layer, and high-temperature baking completely removes the residual solvent, completing the complete curing of the adhesive layer. The second coating head unit 6 achieves quantitative coating of low-viscosity adhesive. Then, the UV curing unit 8 achieves rapid curing of the orange peel texture. Finally, the tape is collected and organized by the winding unit 9.

[0056] In a preferred embodiment, the first coating head device 2 includes a first base, a coating roller 10, and a first guide roller; a first material trough is provided on the first base; the coating roller 10 and the first guide roller are rotatably connected to the first base; a portion of the coating roller 10 is immersed in the first material trough, and the adhesive tape is wound onto the coating roller 10 to achieve the coating of the first layer of adhesive, and then output from between the coating roller 10 and the first guide roller.

[0057] In the technical solution of this application, by precisely adjusting the base amount of adhesive layer by controlling the impregnation depth, and in conjunction with the linkage control of the rotation speed of the coating roller 10 and the conveyor belt speed, a stable and uniform coating of high-viscosity adhesive (3500-4500 cps) can be achieved, avoiding excessively thick adhesive layers that drip or excessively thin layers that expose the substrate. The coating roller 10 and the first guide roller form a roller gap clamping and guiding structure, which can not only scrape off excess adhesive from the surface of the conveyor belt and further calibrate the adhesive layer thickness, but also provide traction and shaping for the coated conveyor belt, preventing the conveyor belt from shifting or wrinkling due to uneven tension after coating, thus providing a flat and stable adhesive layer substrate for the subsequent texture forming process of the fan 3.

[0058] In a preferred embodiment, the second coating head device 6 includes a second base 61, an anilox roller 7, and a second guide roller 62. A second material trough is provided on the second base 61, and the anilox roller 7 and the second guide roller 62 are rotatably connected to the second base. A portion of the anilox roller 7 is immersed in the second material trough, and the tape is wound onto the anilox roller 7 to achieve the coating of the second layer of adhesive, and then output from between the anilox roller 7 and the second guide roller 62.

[0059] In the technical solution of this application, the anilox roller 7 is immersed in the second material tank. With the linkage between the rotation speed and the tape speed, the adhesive can be stably transferred to the surface of the tape. This will not cover the venting channels in the troughs, and can uniformly form the upper layer of orange peel texture, achieving the functional complementarity of the two layers of texture. The anilox roller and the second guide roller are rotatably connected and form a roller gap clamping and output structure: on the one hand, it can scrape off excess adhesive and further calibrate the coating thickness; on the other hand, it can pull the tape to prevent deviation and wrinkling caused by uneven tension after the adhesive is applied, ensuring the stability of subsequent curing and processing.

[0060] In a preferred embodiment, the outer surface of the anilox roller 7 is provided with an orange peel texture, the mesh number of which is 70-90 and the processing depth of which is 90-110μm.

[0061] In the technical solution of this application, the anilox roller 7 replaces the ordinary coating roller 10. The cell structure on its surface can accurately measure and transfer low-viscosity adhesive (1500-2500 cps), solving the pain points of low-viscosity adhesive being prone to sagging and difficult to control the coating amount. The volume and density of the cells can match the target coating height of 3-5μm orange peel texture, realizing the quantitative supply of adhesive and ensuring the consistency of coating thickness.

[0062] For any parts not mentioned in this application, existing technologies may be used or referenced.

[0063] The various embodiments in this specification are described in a progressive manner. The same or similar parts between the various embodiments can be referred to each other. Each embodiment focuses on describing the differences from other embodiments.

[0064] The above description is merely an embodiment of this application and is not intended to limit the scope of this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the scope of the claims of this application.

Claims

1. A process for preparing sealing tape, characterized in that the steps include... include: S1: The base film of the tape is output from the unwinding device to the first coating head device for coating the first layer of adhesive; S2: The fan blows air onto the first layer of colloid, causing the first layer of colloid to form fine water ripples; S3: The first layer of colloid is baked in an oven to set the fine water ripples; S4: The second layer of colloid is coated by the second coating head device and pressed by the anilox roller on the second coating head device, so that the second layer of colloid forms an orange peel texture. S5: The orange peel texture is fixed by a UV curing device; S6: The tape is wound up using a winding device.

2. The preparation process of the sealing tape as described in claim 1, characterized in that, Before S1, the first adhesive needs to be filled into the first material tank of the first coating head device, and a surfactant is added to the first adhesive to make the viscosity range 3500-4500cps; the second adhesive is filled into the second material tank of the second coating head device, and a photoinitiator is added to the second adhesive to make the viscosity range 1500-2500cps.

3. The preparation process of the sealing tape as described in claim 1, characterized in that, The fan is positioned 20-30cm above the first coating head device, with an inclination angle of 40-50°. The fan has a flat air outlet facing the base film, and the airflow is 40-55Hz, which causes the fine water ripples to be distributed in a wave-like pattern along the transverse direction of the tape.

4. The preparation process of the sealing tape as described in claim 1, characterized in that, The oven has at least three sections, wherein the temperature of the first section reaches at least 70°C, the temperature of the second section reaches at least 100°C, and the temperature of the third section reaches at least 120°C.

5. The preparation process of the sealing tape as described in claim 1, characterized in that, Fine water ripples form crest and trough regions on the first layer of colloid, with the crest region having a height of 15-25 μm and the trough region having a height of 5-15 μm.

6. The preparation process of the sealing tape as described in claim 1, characterized in that, Orange peel texture can adhere to the fine water ripple pattern and form a height of 3-5μm.

7. An apparatus for preparing sealing tape, based on the preparation process of sealing tape according to any one of claims 1-6, characterized in that, include: An unwinding device for winding the base film of the adhesive tape; The first coating head device is used to receive the base film output from the unwinding device and coat one side of the base film with a first layer of colloid. A blower is used to blow air toward the first layer of colloid, forming fine water ripples in the first layer of colloid. An oven is used to blow air onto the tape passing through the fan, curing the fine water ripples into a solid shape. The second coating head device is used to coat the tape with a second layer of adhesive and form an orange peel texture; A UV curing device is used to cure and shape the orange peel texture. A winding device is used to collect the tape.

8. The apparatus for preparing sealing tape as described in claim 7, characterized in that, The first coating head device includes a first base, a coating roller, and a first guide roller; A first material trough is provided on the first base; a coating roller and a first guide roller are rotatably connected on the first base; a portion of the coating roller is immersed in the first material trough, and tape is wound onto the coating roller to achieve the coating of the first layer of adhesive, and then output from between the coating roller and the first guide roller.

9. The apparatus for preparing sealing tape as described in claim 7, characterized in that, The second coating head device includes a second base, an anilox roller, and a second guide roller; A second material trough is provided on the second base, and an anilox roller and a second guide roller are rotatably connected to the second base; a portion of the anilox roller is immersed in the second material trough, and tape is wound onto the anilox roller to achieve the coating of the second layer of adhesive, and then output from between the anilox roller and the second guide roller.

10. The apparatus for preparing sealing tape as described in claim 9, characterized in that, The outer surface of the anilox roller is covered with an orange peel texture, with a mesh size of 70-90 and a processing depth of 90-110μm.

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