ECL inbred rat SNP locus typing and application

By using PCR amplification with 21 SNP marker sites and specific primer sequences for ECL inbred rat strain identification, the problem of insufficient identification accuracy in existing technologies has been solved, achieving efficient and accurate identification and genetic monitoring of inbred rat strains.

CN122303435APending Publication Date: 2026-06-30SHAANXI PROVINCIAL INSTITUTE OF TRADITIONAL CHINESE MEDICINE (SHAANXI PROVINCIAL TRADITIONAL CHINESE MEDICINE HOSPITAL SHAANXI PROVINCIAL INSTITUTE OF INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE)

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHAANXI PROVINCIAL INSTITUTE OF TRADITIONAL CHINESE MEDICINE (SHAANXI PROVINCIAL TRADITIONAL CHINESE MEDICINE HOSPITAL SHAANXI PROVINCIAL INSTITUTE OF INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE)
Filing Date
2025-12-31
Publication Date
2026-06-30

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Abstract

This invention belongs to the technical field of identification and genetic quality control of inbred rat strains in laboratory animals. Specifically, it discloses a method for identifying ECL inbred rat strains using 21 SNP markers, including the preparation of kits or detection site sequences, primer sequences, nucleotide types, and their applications. The invention relates to the use of 21 SNP markers for the identification of ECL inbred rat strains, wherein the SNP markers include 21 SNP sites; the inbred rat strain is the ECL inbred rat strain. This invention uses 21 SNP markers to identify ECL inbred rats, and the detection results show that all 21 SNP sites in the ECL inbred rats are homozygous, improving the accuracy of inbred rat strain identification.
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