Composition comprising biosurfactant, ethanol and dye

Abstract

The present invention relates to a composition comprising A) at least one biosurfactant, B) ethanol and C) at least one dye.

Description

Invention Field

[0001] The present invention relates to a composition comprising A) at least one biosurfactant, B) ethanol and C) at least one dye. Existing technology

[0002] In the field of oral care formulations, good aesthetic properties and a desirable appearance are very important.

[0003] In addition to classic toothpaste formulations, mouthwash formulations are also highly relevant. These liquid products achieve high surface contact with the oral cavity, reach hard-to-reach areas, and are very easy to use.

[0004] Many formulations in this field contain ethanol as an ingredient. Colored mouthwashes help draw attention to a particular product and are sometimes associated with a specific fragrance. It is also known that the color of ethanol-containing formulations can fade over time. Various solutions have been proposed in the prior art to combat the discoloration effect. WO2009023393 discloses a composition for minimizing color fading in oral care compositions, comprising a) a silica-shell nanoparticle matrix encapsulated with an organic dye, b) a physiologically stable compound providing fluoride ions, and c) a physiologically stable compound providing peroxide species, in an amount of about 1% to about 20% by weight.

[0005] EP2617466B1 discloses a mouthwash composition having a pH of 4.0 to 6.5, comprising: a) at least one dye, b) 65 to 92.5% by weight of water, and c) 0.02 to 1% by weight of (one or more) fluorides (in the form of F...). - (Calculation), d) ≤ 1% by weight of ethanol, e) ≤ 1% by weight of (one or more) peroxides (calculated as 100% H2O2).

[0006] The object of the present invention is to provide an ethanol composition comprising at least one dye, which has improved color stability.

[0007] Description of the present invention It has been surprisingly found that incorporating biosurfactants into coloring compositions can lead to improved color stability.

[0008] Therefore, the present invention provides a composition comprising A) at least one biosurfactant, B) ethanol and C) at least one dye.

[0009] The present invention further provides the use of the compositions according to the invention for oral cosmetic cleaning, and the use of biosurfactants for stabilizing dyes in ethanol solutions.

[0010] One advantage of the present invention is that the compositions of the present invention have improved color stability.

[0011] Another advantage of the present invention is that the compositions of the present invention have faster processability.

[0012] Another advantage of the present invention is that the composition of the present invention has faster rinseability.

[0013] One advantage of the present invention is that the compositions of the present invention can have enhanced activity of the contained peroxides.

[0014] Another advantage of the present invention is that the compositions of the present invention can enhance the effect of the fluorides contained in the compositions.

[0015] Another advantage of the present invention is that the composition of the present invention has good antibacterial properties.

[0016] Another advantage of the present invention is that it allows for a reduction in the amount of sweetener in the composition.

[0017] Another advantage of this invention is that it reduces discoloration of the packaging.

[0018] Another advantage of the present invention is that it improves the foaming properties of the composition.

[0019] Another advantage of this invention is its improved mildness.

[0020] Another advantage of the present invention is that they leave a smooth and soft feel after washing.

[0021] Another advantage of this invention is that it can reduce the amount of surfactant.

[0022] Another advantage of this invention is that it improves the transparency of the formulation.

[0023] Another advantage of the present invention is that the composition causes a reduction in tooth staining.

[0024] Another advantage of the present invention is that it improves the taste of the composition.

[0025] Another advantage of the present invention is that the composition reduces dental plaque.

[0026] Another advantage of the present invention is that the composition reduces bad breath.

[0027] This invention provides a composition comprising A) At least one biosurfactant, B) Ethanol, and C) At least one dye.

[0028] In the context of this invention, "biosurfactant" is understood to mean all glycolipids and their salts produced by fermentation. The term "biosurfactant" also covers glycolipids that have been chemically or enzymatically modified after fermentation, provided that the glycolipid structure is retained. When determining the amount of biosurfactant, only the mass of the biosurfactant is considered, without regard to the counterion of the salt, if the biosurfactant is present in salt form.

[0029] Raw materials that can be used to produce biosurfactants are carbohydrates, especially sugars such as glucose and / or lipophilic carbon sources such as fats, oils, glycerides, fatty acids, fatty alcohols, and long-chain saturated or unsaturated hydrocarbons.

[0030] In the context of this invention, the term "surfactant" is understood to mean an organic substance with interfacial active properties that has the ability to reduce the surface tension of water to below 45 mN / m at 20°C and at a concentration of 0.5% by weight based on the total composition. Surface tension was determined at 20°C by the Du Noüy ring method.

[0031] In the context of this invention, the term "liquid" is understood to mean liquid at a temperature of 25°C and a pressure of 1013 mbar.

[0032] In the context of the following discussion of averages, unless otherwise stated, these are multiple averages.

[0033] Unless otherwise stated, percentages are by weight. The same applies to parts per million (ppm).

[0034] Unless otherwise stated, all measurements described below were taken at a temperature of 25°C and a pressure of 1013 mbar.

[0035] The composition according to the present invention is preferably characterized in that the biosurfactant is selected from rhamnolipids, sophorolipids, glycolipids, cellulose lipids, mannose erythritol lipids and trehalolipids, preferably rhamnolipids, sophorolipids and glycolipids, more preferably rhamnolipids and glycolipids, and most preferably rhamnolipids.

[0036] Of course, the compositions of the present invention may contain a mixture of different biosurfactants.

[0037] The biosurfactant may be produced, for example, according to the following documents: EP 0 499 434, US 7,985,722, WO 03 / 006146, DE 19648439, DE 19600743, JP 01 304034, CN 1337439, JP 2006 274233, JP 2006 083238, JP 2006 070231, WO 03 / 002700, FR 2740779, DE 2939519, US 7,556,654, FR 2855752, EP 1445302, JP 2008 062179 and JP 2007 181789 or the documents cited therein. Suitable biosurfactants may be obtained, for example, from Soliance, France.

[0038] Preferably, the composition according to the invention is characterized in that the biosurfactant is selected from rhamnolipids, particularly mono-, di- or poly-rhamnolipids; glycolipids, particularly mono-, di- or poly-glycolipids; and sophorolipids, particularly mono-, di- or poly-sophora sophorolipids; preferably selected from rhamnolipids and glycolipids, most preferably rhamnolipids.

[0039] In the context of this invention, the term "rhamnolipid" is preferably understood to mean, in particular, compounds of general formula (I) and their salts. Formula (I) in mRL = 2, 1, or 0, preferably 1 or 0. nRL = 1 or 0, R 1RL and R 2RL =Independent, identical or different organic residues having 2 to 24, preferably 5 to 13 carbon atoms, particularly optionally branched, optionally substituted, especially hydroxylated, optionally unsaturated, especially optionally mono-, di- or tri-unsaturated alkyl residues, preferably selected from pentenyl, heptenyl, nonenyl, undecenyl and tridecenyl and (CH2). o -CH3, where o = 1 to 23, preferably 4 to 12.

[0040] If nRL = 1, the glycosidic bond between the two rhamnose units is preferably in the α-configuration. The optically active carbon atom of the fatty acid is preferably present as an R-enantiomer (e.g., (R)-3-{(R)-3-[2-O-(α-L-pyranorhamnosyl)-α-L-pyranorhamnosyl]oxydecanoyl}oxydecanoate).

[0041] In the context of this invention, the term "di-rhamnolipid" is understood to mean a compound of general formula (I) or a salt thereof, wherein nRL = 1.

[0042] In the context of this invention, the term "monororhamnetin" is understood to mean a compound of general formula (I) or a salt thereof, where nRL = 0.

[0043] Different rhamnolipides are named according to the following abbreviations: “diRL-CXCY” is understood to refer to the di-rhamnolipid of general formula (I), in which residue R… 1RL and R 2RL One of them is (CH2). o -CH3, where o = X-4, and the remaining residues R 1 or R 2 (CH2) o -CH3, where o = Y-4.

[0044] “monoRL-CXCY” is understood to refer to a mono-rhamnolipid of formula (I), in which residue R 1RL and R 2RL One of them is (CH2). o -CH3, where o = X-4, and the remaining residues R 1RL or R 2RL (CH2) o -CH3, where o = Y-4.

[0045] Therefore, the naming convention used does not distinguish between "CXCY" and "CYCX".

[0046] For rhamnolipids where mRL=0, use monoRL-CX or diRL-CX accordingly.

[0047] If one of the aforementioned markers X and / or Y is provided with ":Z", then this indicates that the corresponding residue R 1RL and / or R 2RL It is equivalent to an unbranched, unsubstituted hydrocarbon residue with X-3 or Y-3 carbon atoms that has Z double bonds.

[0048] Methods for preparing related rhamnolipids are disclosed, for example, in EP2786743 and EP2787065.

[0049] Rhamnolipids, in the context of this invention, can also be transmitted via Pseudomonas aeruginosa ( Pseudomonas ), especially Pseudomonas aeruginosa ( Pseudomonas aeruginosaRhamnolipin is produced by fermentation of cells, preferably non-genetically modified cells, a technique disclosed in the 1980s, as described, for example, in EP0282942 and DE4127908. Rhamnolipin produced in Pseudomonas aeruginosa cells (which have been genetically modified for higher rhamnolipin titers) can also be used in the context of this invention; such cells have been disclosed, for example, by Lei et al. in Biotechnol Lett. 2020 Jun;42(6):997-1002.

[0050] Rhamnolipids produced by Pseudomonas aeruginosa are commercially available from Jeneil Biotech Inc., for example under the trade name Zonix; from Logos Technologies (technology acquired by Stepan), for example under the trade name NatSurFact; from Biotensidion GmbH, for example under the trade name Rhapynal; from AGAE technologies, for example under the names R90, R95, R95Md, R95Dd; from Locus Bio-Energy Solutions; and from Shanghai Yusheng Industry Co. Ltd., for example under the trade name Bio-201 Glycolipids.

[0051] This invention provides a composition, preferably comprising rhamnolipid as the biosurfactant, characterized in that the rhamnolipid comprises 51% to 100% by weight, preferably 60% to 95% by weight, particularly preferably 80% to 90% by weight of mono-rhamnolipids, especially those in formula (I) where nRL=0. The percentage by weight is calculated based on the total amount of rhamnolipids contained in the liquid composition.

[0052] The present invention provides a composition, alternatively preferably comprising rhamnolipid as the biosurfactant, characterized in that the rhamnolipid comprises 71% to 100% by weight, preferably 75% to 95% by weight, particularly preferably 80% to 90% by weight of di-rhamnolipids, especially those in formula (I) where nRL=1. The percentage by weight is calculated based on the total amount of rhamnolipids contained in the liquid composition.

[0053] The present invention further provides a composition, preferably comprising rhamnolipid as the biosurfactant, characterized in that the rhamnolipid comprises diRL-C10C10 comprises 56% to 95% by weight, preferably 60% to 80% by weight, and particularly preferably 66% to 70% by weight. The percentage by weight is calculated based on the total amount of rhamnolipids contained in the liquid composition.

[0054] The preferred composition according to the present invention is characterized in that the biosurfactant is the rhamnolipin described above, and its content is: 0.5% to 15% by weight, preferably 3% to 12% by weight, particularly preferably 5% to 10% by weight of diRL-C10C12:1, The percentage by weight is calculated based on the total amount of rhamnolipids contained in the liquid composition.

[0055] A further preferred embodiment of the composition according to the present invention is characterized in that the biosurfactant is the rhamnolipin described above, and its content is: 0.5% to 25% by weight, preferably 3% to 15% by weight, particularly preferably 5% to 12% by weight of diRL-C10C12. The percentage by weight is calculated based on the total amount of rhamnolipids contained in the liquid composition.

[0056] The preferred composition according to the present invention is characterized in that the biosurfactant is the rhamnolipin described above, and its content is: 0.1% to 25% by weight, preferably 2% to 10% by weight, particularly preferably 4% to 8% by weight of diRL-C8C10, The percentage by weight is calculated based on the total amount of rhamnolipids contained in the liquid composition.

[0057] The composition according to the present invention, and even a further preferred one, is characterized in that the biosurfactant is the rhamnolipin described above, and its content is: 0.1% to 5% by weight, preferably 0.5% to 3% by weight, particularly preferably 0.5% to 2% by weight of monoRL-C8C10 and / or, preferably and 0.1% to 5% by weight, preferably 0.5% to 3% by weight, particularly preferably 0.5% to 2% by weight of monoRL-C10C10. The percentage by weight is calculated based on the total amount of rhamnolipids contained in the liquid composition.

[0058] The present invention provides a composition, which alternatively preferably comprises rhamnolipid as the biosurfactant, characterized in that the rhamnolipid comprises 10% to 30% by weight, preferably 20% to 30% by weight, and particularly preferably 25% to 30% by weight of monoRL-C10C10. The percentage by weight is calculated based on the total amount of rhamnolipids contained in the liquid composition.

[0059] An alternative preferred composition according to the invention is characterized in that the biosurfactant is the rhamnolipin described above, and its content is: diRL-C10C10, 10% to 30% by weight, preferably 12% to 25% by weight, particularly preferably 15% to 20% by weight. The percentage by weight is calculated based on the total amount of rhamnolipids contained in the liquid composition.

[0060] The preferred alternative composition according to the present invention is characterized in that the biosurfactant is the rhamnolipin described above, and its content is: monoRL-C8C10, 10% to 30% by weight, preferably 12% to 25% by weight, and particularly preferably 15% to 20% by weight. The percentage by weight is calculated based on the total amount of rhamnolipids contained in the liquid composition.

[0061] The preferred alternative composition according to the invention is characterized in that the biosurfactant is the rhamnolipin described above, and its content is [missing information]. 3% to 25% by weight, preferably 5% to 20% by weight, particularly preferably 10% to 15% by weight of monoRL-C10C12:1 The percentage by weight is calculated based on the total amount of rhamnolipids contained in the liquid composition.

[0062] The preferred alternative composition according to the present invention is characterized in that the biosurfactant is the rhamnolipin described above, and its content is [missing information]. 1% to 15% by weight, preferably 2% to 10% by weight, particularly preferably 3% to 8% by weight of diRL-C10C12. The percentage by weight is calculated based on the total amount of rhamnolipids contained in the liquid composition.

[0063] Methods for preparing related rhamnolipids are disclosed, for example, in EP2786743 and EP2787065.

[0064] Rhamnolipids, as used in the context of this invention, can also be transmitted via Pseudomonas aeruginosa ( PseudomonasRhamnolipids are produced, particularly by fermentation of *Pseudomonas aeruginosa* (preferably non-genetically modified cells), a technique disclosed in the 1980s, as described, for example, in EP0282942 and DE4127908. Rhamnolipids produced from *Pseudomonas aeruginosa* cells that have been genetically modified for higher rhamnolipid titers can also be used in the context of this invention; such cells have been disclosed, for example, by Lei et al. in *Biotechnol Lett. 2020 Jun;42(6):997-1002*.

[0065] Rhamnolipids produced by Pseudomonas aeruginosa are commercially available from Jeneil Biotech Inc., for example under the trade name Zonix; from Logos Technologies (technology acquired by Stepan), for example under the trade name NatSurFact; from Biotensidion GmbH, for example under the trade name Rhapynal; from AGAE technologies, for example under the names R90, R95, R95Md, R95Dd; from Locus Bio-Energy Solutions; and from Shanghai Yusheng Industry Co. Ltd., for example under the trade name Bio-201 Glycolipids.

[0066] In the context of this invention, the term "sophorolipid" is preferably understood to mean compounds of general formulas (IIa) and (IIb) and their salts. Formula (IIa) Equation (IIb) in R 1SL = H or CO-CH3, R 2SL = H or CO-CH3, R 3SL = A divalent organic moiety containing 6 to 32 carbon atoms that are either unsubstituted or functionally substituted with hydroxyl groups, which is unbranched and optionally contains one to three double or triple bonds. R 4SL = H, CH3, or a monovalent organic group containing 2 to 10 carbon atoms that is unsubstituted or functionally substituted with a hydroxyl group, which is unbranched and optionally contains one to three double or triple bonds, and nSL = 1 or 0.

[0067] According to the present invention, sophorolipids can be used in their acid form or their lactone form.

[0068] Preferred compositions according to the invention comprise sophorolipids, wherein the ratio of lactone form to acid form by weight is in the range of 20:80 to 80:20, particularly preferably in the range of 30:70 to 40:60.

[0069] To determine the content of sophorolipids in the formulation in acid or lactone form, refer to EP1411111B1, page 8, paragraph

[0053] .

[0070] In connection with this invention, the term "glycolipid" is preferably understood to mean compounds of general formula (III) and their salts. Equation (III) in mGL = 3, 2, 1 or 0, preferably 1 or 0. R 1GL and R 2GL = Organic groups having 2 to 24 carbon atoms, either independently identical or different from each other, particularly optional branched, optional substituted, especially hydroxylated, optional unsaturated, especially optional mono-, di-, or tri-unsaturated alkyl groups, preferably selected from pentenyl, heptenyl, nonenyl, undecenyl, and tridecenyl, as well as (CH2). o -CH3, where o = 1 to 23, preferably 4 to 12.

[0071] Different glycolipids are abbreviated according to the following naming convention: "GL-CXCY" is understood to refer to glycolipids of general formula (III), in which the group R 1GL and R 2GL One of them is (CH2). o -CH3, where o = X-4, and the remaining group R 1GL or R 2GL (CH2) o -CH3, where o = Y-4.

[0072] Therefore, the naming convention used does not distinguish between "CXCY" and "CYCX".

[0073] If one of the above-mentioned markings X and / or Y is provided with ":Z", then this indicates that the corresponding group R 1GL and / or R 2GL = An unbranched, unsubstituted hydrocarbon group with Z double bonds and X-3 or Y-3 carbon atoms.

[0074] The method for producing glycolipids can be carried out as described in WO2019154970.

[0075] The preferred composition according to the present invention is characterized in that it comprises A) The amount is from 0.2% to 10.0% by weight, preferably from 0.5% to 7.0% by weight, more preferably from 0.8% to 5.0% by weight. The weight percentages are based on the total composition.

[0076] The preferred composition according to the present invention is characterized in that it comprises a non-biological surfactant, preferably selected from anionic, cationic, nonionic, semi-polar, amphoteric and zwitterionic surfactants, and more preferably selected from anionic and nonionic surfactants.

[0077] Clearly, the non-biological surfactants mentioned are different from those surfactants in component A).

[0078] The preferred non-biological surfactants included in the compositions of the present invention are selected from sodium lauryl sulfate and poloxamer. Preferably, sodium lauryl sulfate and at least one poloxamer, preferably poloxamer 407, are included in the preferred compositions according to the present invention.

[0079] The preferred composition according to the invention is characterized in that it comprises a total amount of all surfactants in an amount of 0.2% to 12.0% by weight, preferably 0.5% to 8% by weight, more preferably 0.8% to 6% by weight, wherein the percentage by weight refers to the total composition.

[0080] The preferred composition according to the invention is characterized in that component B) is included in an amount of 5.0% to 50% by weight, preferably 8.0% to 40.0% by weight, more preferably 14.0% to 30.0% by weight, wherein the percentage by weight refers to the total composition.

[0081] The preferred composition according to the invention is characterized in that component C) is selected from the group consisting of, preferably, the following: CI 42053, also known as Fast Green FCF; CI 42090, also known as Brilliant Blue FCF; CI 16035, also known as Food Red 40; CI 42051, also known as Acid Blue 3 and Patent Blue V; indigo-based colorants, such as CI 73015; CI 16185, also known as Amaranth Red; CI 14720, also known as Azo Ruby Red; Acid blue dyes, preferably selected from CI 42045, also known as Acid Blue 1; CI 42080, also known as Acid Blue 7; CI 62070, also known as Acid Blue 145; Acid Blue 182; CI 74200, also known as Acid Blue 185; CI 15707, also known as Acid Blue 193; CI 42090, also known as CI Acid Blue 9; and CI 42780, also known as CI Acid Blue 93; CI 77007, also known as CI Pigment Blue 29; CI Solvent Blue 3 and CI Reactive Blue 116; preferably CI 42053, also known as Fast Green FCF; CI 42090, also known as Brilliant Blue FCF; CI 16035, also known as Food Red 40.

[0082] The preferred composition according to the present invention is characterized in that it comprises C) The amount is 0.00005% by weight to 0.01% by weight, preferably 0.00001% by weight to 0.005% by weight, more preferably 0.0002% by weight to 0.001% by weight, wherein the percentage by weight is based on the total composition.

[0083] The preferred composition according to the present invention is characterized in that it comprises D) At least one sweetener.

[0084] Component D) in the composition according to the invention is preferably selected from the group consisting of, and more preferably, the following: Xylitol, sorbitol, sucralose, acesulfame potassium (preferably), and saccharin (preferably sodium saccharin).

[0085] The preferred composition according to the invention is characterized in that it comprises D) The sweetener is in the form of a polyol-based sweetener, preferably selected from xylitol, sorbitol and sucralose, in an amount of 0.2% to 12.0% by weight, preferably 0.5% to 8% by weight, more preferably 0.8% to 6% by weight, wherein the percentage by weight is based on the total composition.

[0086] The alternative preferred composition according to the invention is characterized in that it comprises D) A dietary-grade, non-polyol-based sweetener, preferably selected from acesulfame potassium, and saccharin, preferably sodium saccharin, in an amount of 0.02% to 1.0% by weight, preferably 0.05% to 0.8% by weight, more preferably 0.2% to 0.5% by weight, wherein the percentage by weight is based on the total composition.

[0087] The preferred composition according to the invention is characterized in that it comprises E) At least one component that provides fluoride ions.

[0088] Component E) in the composition according to the invention is preferably selected from the group consisting of, and more preferably, the following: Sodium fluoride, potassium fluoride, calcium fluoride, magnesium fluoride, stannous fluoride, stannous monofluorophosphate, sodium monofluorophosphate, sodium fluorosilicate, ammonium fluorosilicate, amine fluorides, and copper fluoride.

[0089] The preferred composition according to the invention is characterized in that it comprises E) The amount provides 25 ppm to 5,000 ppm of fluoride ions, wherein the ppm is based on the total composition.

[0090] The preferred composition according to the invention is characterized in that it comprises F) At least one oral-acceptable peroxide.

[0091] Component D) in the composition according to the invention is preferably selected from the group consisting of, and more preferably, the following: Hydrogen peroxide, urea peroxide, calcium peroxide, and carbamate peroxide.

[0092] The preferred composition according to the invention is characterized in that it comprises F) The amount is from 0.05% to 3.0% by weight, preferably from 0.1% to 2.0% by weight, more preferably from 0.5% to 1.5% by weight, wherein the percentage by weight is based on the total composition.

[0093] The present invention works well across a wide range of pH values. Therefore, a preferred composition according to the present invention is characterized by a pH of 3.0 to 10.5 at 25°C, preferably 3.5 to 9.0, and particularly preferably 4.0 to 8.0.

[0094] In connection with this invention, “pH”—unless otherwise stated—is defined as the value of the relevant composition determined by stirring at 25°C for five minutes using a pH electrode calibrated according to ISO 4316 (1977).

[0095] When it comes to, for example, mouthwash, there are two different product concepts available: alkaline and acidic products.

[0096] In cases where an alkaline composition is desired, a preferred composition according to the invention is characterized in that the composition has a pH of 7.4 to 10.5 at 25°C.

[0097] In cases where an acidic composition is desired, an alternative preferred composition according to the invention is characterized in that the composition has a pH of 4.8 to 6.1 at 25°C.

[0098] The preferred compositions according to the invention are cosmetic or pharmaceutical preparations, preferably cosmetic preparations. These preparations are preferably selected from mouthwashes and oral rinsing solutions.

[0099] The compositions according to the invention exhibit outstanding capabilities in cleaning and surface sterilization, particularly in cosmetic applications.

[0100] Therefore, another aspect of the present invention is the use of the composition according to the invention for cosmetic cleaning of the oral cavity, particularly the teeth, of subjects, preferably humans. This use is, of course, non-therapeutic.

[0101] Another aspect of the present invention is the use of the composition according to the invention for the prevention of dental caries.

[0102] Another aspect of the invention is the use of biosurfactants for stabilizing dyes in ethanol solutions (preferably in terms of fading, especially due to light exposure).

[0103] Preferably, the biosurfactant according to the invention is characterized in that it is selected from rhamnolipin, glycolipid and sophorolipid, preferably rhamnolipin and glycolipid, and most preferably rhamnolipin.

[0104] In the case of the application according to the invention, particularly preferred embodiments of the composition according to the invention and its preferred components are similarly preferred, also in preferred amounts.

[0105] The embodiments cited below describe the invention by way of example, and are not intended to limit the invention (the scope of which is obvious from the entire specification and claims) to the embodiments specified in the examples.

[0106] Example: To measure the color of freshly prepared and aged formulations, the International Color System (CIELAB: L*, a*, b*) was used. ΔE* indicates the color difference between the aged sample and the post-production formulation.

[0107] Example 1: Oral rinsing solution according to the present invention The given value is the weight percentage of the active substance relative to the total composition. RHEANCE® One (glycolipid) 0.2 Fragrance ("Mintfresh", Bell) 0.2 water ad 100 ethanol 15.0 Sorbitol (70%) 4.0 Sodium saccharin 0.07 benzoic acid 0.12 Dye (CI 42090 (Brilliant Blue FCF)) (0.1% in water) 0.25

[0108] Dissolve the fragrance in RHEANCE® One. Mix water and ethanol. Slowly add this mixture to the RHEANCE® One and fragrance mixture while stirring. Add the remaining ingredients in the given order.

[0109] Example 2: Oral rinsing solution not based on the present invention The given value is the weight percentage of the active substance relative to the total composition. Polosham 407 0.2 Fragrance ("Mintfresh", Bell) 0.2 water ad 100 ethanol 15.0 Sorbitol (70%) 4.0 Sodium saccharin 0.07 benzoic acid 0.12 Dye (CI 42090 (Brilliant Blue FCF)) (0.1% in water) 0.25

[0110] Dissolve the fragrance in poloxamer 407. Mix water and ethanol. Slowly add this mixture to the poloxamer 407 and fragrance mixture while stirring. Add the remaining ingredients in the given order.

[0111] Example 3: Color Stability After preparation, the samples were stored at 25°C in the dark or under UV exposure (sunlight). Color values ​​were measured before and after storage.

[0112] As can be seen from the ΔE-difference, the compositions according to the present invention experience far less color fading than the compositions not of the present invention.

Claims

1. A composition comprising A) At least one biosurfactant, B) Ethanol, and C) At least one dye.

2. The composition according to claim 1, characterized in that... The biosurfactant is selected from rhamnolipin, glycolipid and sophorolipid, preferably rhamnolipin and glycolipid, and most preferably rhamnolipin.

3. The composition according to claim 1 or 2, characterized in that... Component B) is contained in an amount of 5.0% to 50% by weight, preferably 8.0% to 40.0% by weight, more preferably 14.0% to 30.0% by weight, wherein the percentage by weight is based on the total composition.

4. The composition according to at least one of the preceding claims, characterized in that... Component C) is selected from: CI 42053, CI 42090, CI 16035, CI 42051, CI 73015, CI 16185, CI 14720, and Acid Blue dyes, preferably selected from CI 42045, CI 42080, CI 62070, Acid Blue 182, CI 74200, CI 15707, CI 42090 and CI 42780, CI 77007, CI Solvent Blue 3 and CI Reactive Blue 116.

5. The composition according to at least one of the preceding claims, characterized in that... It contains C) The amount is 0.00005% by weight to 0.01% by weight, preferably 0.00001% by weight to 0.005% by weight, more preferably 0.0002% by weight to 0.001% by weight, wherein the percentage by weight is based on the total composition.

6. The composition according to at least one of the preceding claims, characterized in that... It contains D) At least one sweetener.

7. The composition according to claim 6, characterized in that... Component D) is selected from: xylitol, sorbitol, sucralose, acesulfame potassium, preferably acesulfame potassium, and saccharin, preferably sodium saccharin.

8. The composition according to at least one of the preceding claims, characterized in that... It contains E) At least one component that provides fluoride ions.

9. The composition according to claim 8, characterized in that... Component E) is selected from: sodium fluoride, potassium fluoride, calcium fluoride, magnesium fluoride, stannous fluoride, stannous monofluorophosphate, sodium monofluorophosphate, sodium fluorosilicate, ammonium fluorosilicate, amine fluoride and copper fluoride.

10. The composition according to claim 8 or 9, characterized in that... It includes: E) The amount provides 25 ppm to 5,000 ppm of fluoride ions, where ppm is based on the total composition.

11. The composition according to at least one of the preceding claims, characterized in that... It contains F) At least one oral-acceptable peroxide, preferably selected from hydrogen peroxide, urea peroxide, calcium peroxide, and carbamate peroxide.

12. The composition according to claim 11, characterized in that... It includes: F) The amount is from 0.3% to 6.0% by weight, preferably from 0.3% to 3.0% by weight, more preferably from 1.0% to 2.0% by weight, wherein the percentage by weight is based on the total composition.

13. The composition according to at least one of the preceding claims, characterized in that... The composition has a pH of 3.0 to 10.5 at 25°C, preferably 3.5 to 9.0, and particularly preferably 4.0 to 8.

0.

14. The use of the composition according to at least one of claims 1 to 13 for cosmetic cleaning of the oral cavity, preferably of a human subject, and particularly of teeth.

15. Biosurfactants are used to stabilize dyes in ethanol solutions, preferably in fading, especially due to light exposure.

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