Eggshell membrane peptide capable of resisting oxidation and improving motion ability of aging body and application of eggshell membrane peptide

By identifying the antioxidant peptide EQPWFPAG from eggshell membrane, the problems of low bioavailability and insufficient protection against oxidative stress in eggshell membrane have been solved, achieving the effects of improving the physical function of aging organisms and prolonging lifespan. It can be applied to functional food and pharmaceutical compositions.

CN122356221APending Publication Date: 2026-07-10HUIZHOU MILAIMI FOOD CO LTD +3
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Patent Information

Application Number
CN202610583058.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-04-29
Publication Date
2026-07-10

AI Technical Summary

Technical Problem

Current technologies lack eggshell membrane peptides that can simultaneously improve the motor function of aging organisms, and the bioavailability of eggshell membranes is limited, with a lack of research on protective peptides under oxidative stress conditions.

Method used

An antioxidant peptide, Glu-Gln-Pro-Trp-Phe-Pro-Ala-Gly (EQPWFPAG), was identified from eggshell membrane hydrolysate. This peptide possesses antioxidant activity and the ability to protect bone cells from oxidative stress damage, and can be applied in functional foods, health products, and pharmaceutical compositions.

Benefits of technology

It significantly reduces the level of reactive oxygen species in aging nematodes, enhances their resistance to H2O2 stress, improves their aging motor function, prolongs their lifespan, and protects bone cells against oxidative stress damage.

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Abstract

The invention discloses an eggshell membrane peptide capable of resisting oxidation and improving motion ability of an aging body and application of the eggshell membrane peptide, and belongs to the technical field of biology. The amino acid sequence of the eggshell membrane peptide disclosed by the invention is as shown in SEQ ID NO. 1, and is specifically EQPWFPG. The novel antioxidant peptide EQPWFPG is identified from egg shell membrane hydrolysate, and it is verified that the eggshell membrane peptide can improve the exercise ability and the anti-oxidative stress ability of an aging organism. The eggshell membrane peptide provided by the invention not only can be used for preparing antioxidants, but also can be used for preparing functional foods, health-care products and pharmaceutical compositions for improving motor functions of aging organisms, and has huge application value.
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