Tablet candy for assisting in regulating sleep, improving sleep, enhancing deep sleep and enhancing immunity

Abstract

The present application relates to the technical field of functional food, and particularly relates to a tablet candy for assisting in regulating insomnia, improving deep sleep and enhancing immunity, which is prepared by compounding plant regulating components, functional nutrition components and medicinal excipients in a specific proportion, the plant regulating components are prepared by low-temperature cold extraction or pure water extraction process, and the plant regulating components include Huangjing cold extraction powder, Sangye cold extraction powder, Fuling cold extraction powder, Xiyangshen cold extraction powder, Lingzhi powder and Lianzi water extract. The tablet candy for assisting in regulating insomnia, improving deep sleep and enhancing immunity is prepared by a whole-process mild preparation process combining low-temperature cold extraction, pure water extraction and low-temperature drying, so that the full-spectrum active ingredients in the homologous medicinal and food materials can be retained, the effective substance damage and loss caused by high-temperature processing can be avoided, the plant regulating components and the functional nutrition components can fully play a synergistic role, the process improves the stability and bioavailability of the active ingredients, and the product has a more mild and persistent effect on regulating sleep, improving fatigue and enhancing immunity.

Description

Technical Field

[0001] This invention relates to the field of functional food technology, specifically to a compressed candy that helps regulate insomnia, improves deep sleep, and enhances immunity. Background Technology

[0002] With the fast pace and increasing pressure of modern life, insomnia, poor sleep quality, daytime fatigue, and weakened immunity have become widespread health problems, leading to a continuous rise in demand for functional foods that improve sleep, combat fatigue, and enhance immunity. While there are many types of compressed candy products on the market, they generally suffer from a core technical problem: insufficient synergistic effects, low retention of active ingredients, and formulations and processes that fail to address the triple needs of sleep improvement, daytime fatigue relief, and immune enhancement. Most products use traditional processes such as high-temperature extraction and ordinary pulverization, which easily cause degradation and loss of heat-sensitive active ingredients, significantly reducing their actual efficacy. Formulas often rely on single sleep-aiding ingredients, lacking a two-way synergistic design for nighttime relaxation and daytime alertness, making it difficult to achieve integrated conditioning of sleep improvement, energy restoration, and immune enhancement. Furthermore, many products add excipients such as sucrose, flavorings, and colorings, resulting in poor long-term consumption compliance and unsuitability for special groups such as those controlling their blood sugar.

[0003] The prior art document CN114794289B discloses a compressed candy containing γ-aminobutyric acid and its preparation method. Although it focuses on sleep aid, it only emphasizes the single function of improving sleep and does not form a synergistic system of sleep, anti-fatigue, and immunity. Furthermore, it does not employ a low-temperature full-spectrum extraction process, thus failing to effectively preserve the plant's active ingredients and failing to achieve bidirectional regulation of circadian rhythms and long-term sustained release. Therefore, it cannot overcome the core defects that this invention aims to address. Existing technologies generally fail to integrate low-temperature steady-state extraction, bidirectional circadian rhythm formulation, burden-free formulation, and sustained-release dosage form, making it difficult to meet consumers' demand for safe, efficient, and long-term edible multifunctional health foods. Summary of the Invention

[0004] The purpose of this invention is to provide a compressed candy that helps regulate insomnia, improves deep sleep, and enhances immunity, in order to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a compressed candy that assists in regulating insomnia, improving deep sleep, and enhancing immunity, comprising plant conditioning components, functional nutritional components, and pharmaceutical excipients in a specific ratio. The plant conditioning components are prepared using low-temperature cold extraction or pure water extraction processes, including cold-extracted powders of Polygonatum sibiricum, Mulberry leaf, Poria cocos, American ginseng, Ganoderma lucidum, and lotus seed water extract. The functional nutritional components include γ-aminobutyric acid, tea theanine, phosphatidylserine, calcium lactate, yeast β-glucan, and yeast powder. The pharmaceutical excipients include microcrystalline cellulose, erythritol, hydroxypropyl methylcellulose, sodium carboxymethyl cellulose, and magnesium stearate. The compressed candy contains no added flavorings, sucrose, pigments, or preservatives. The finished product has a single tablet weight of 0.4g to 1.4g, a core weight of 400mg to 1200mg, and a coating weight gain of 20mg to 160mg.

[0006] Preferably, the plant conditioning components are prepared by a three-step process of low-temperature cold extraction at -40℃ to -20℃, pure water extraction at below 45℃, and low-temperature vacuum drying at 38℃ to 50℃. This process can completely preserve the full spectrum of active ingredients in the plants, and the retention rate of effective ingredients is increased by more than 60% compared with traditional high-temperature processes, without damaging or losing heat-sensitive substances.

[0007] Preferably, the compressed candy has a bidirectional circadian rhythm regulation function: at night, through the synergistic effect of Poria cocos, lotus seeds, γ-aminobutyric acid, and tea theanine, it inhibits central nervous system excitation, shortens sleep onset time, and increases the proportion of deep sleep; during the day, through the synergistic effect of American ginseng, Polygonatum sibiricum, phosphatidylserine, and yeast β-glucan, it relieves drowsiness and fatigue, improves brain oxygen supply, and enhances energy and immunity.

[0008] Preferably, the weight ratio of the plant conditioning components to the functional nutrient components is 1:1.2 to 1:1.8, achieving a synergistic effect of calming the nerves and aiding sleep, combating fatigue, enhancing immunity, and boosting energy and spirit, without the shortcomings of single-component efficacy.

[0009] Preferably, a double-layer sustained-release coating of hydroxypropyl methylcellulose is used, which allows for slow dissolution in the stomach and continuous absorption in the intestines, extending the effective duration of action to 8-12 hours and avoiding problems such as short-acting, large peak-to-trough fluctuations, and short-lasting effects.

[0010] The preferred formulation uses erythritol as the sole sweetener, resulting in a sweet and refreshing taste that does not participate in blood sugar metabolism or cause tooth decay. It is suitable for long-term consumption by people who need to control their blood sugar, people who stay up late, people with weakened immunity, and the elderly.

[0011] Preferably, all the plant conditioning components are high-purity cold-extracted powders or water extracts, without any raw material coarse powder filling, the concentration of effective ingredients is increased by 3 to 5 times, the efficacy is stable, the onset is mild, and there is no gastrointestinal irritation.

[0012] Preferably, the product is in the form of film-coated tablets or plain tablets, with a disintegration time of ≤30 minutes, and the content uniformity meets the requirements of food tablets. It is easy to carry, does not require water to take, and is suitable for multiple scenarios such as home, office, and business trips.

[0013] Preferably, any non-substantial dosage form modification, such as changing the compressed candy to capsules, tablets, powders, granules, lozenges, chewable tablets, or pills, falls within the scope of protection of this invention.

[0014] A method for preparing a compressed candy that helps regulate insomnia, improves deep sleep, and enhances immunity includes the following steps, detailed in terms of process parameters, equipment, conditions, and control indicators: S1: Raw material selection and pre-processing Polygonatum, mulberry leaves, Poria cocos, American ginseng, Ganoderma lucidum, and lotus seeds were carefully selected by hand to remove moldy, insect-infested, impurities, and non-medicinal parts. They were then rinsed three times with purified water for at least five minutes each time and allowed to air dry naturally in a clean area. The drained raw materials were then pulverized in a low-temperature pulverizer and passed through a 20-60 mesh pharmacopoeia standard sieve to obtain pre-treated raw material powder. This powder was then sealed and stored in a cool, dry place for later use, with the ambient temperature controlled at 18-25°C and the relative humidity at 40-60%.

[0015] S2: Low-temperature cold extraction preparation Pre-treated raw material powders of Polygonatum sibiricum, mulberry leaves, Poria cocos, and American ginseng were separately added to a low-temperature extraction tank. Purified water was added as the extraction solvent at a material-to-liquid ratio of 1:8 to 1:15. The tank door was closed, and the refrigeration system was started to rapidly lower the temperature inside the tank to -40℃ to -20℃ and maintain a constant temperature. Stirring was started at a speed of 20 to 50 r / min, and the low-temperature cold extraction was carried out for 2 to 4 hours. After extraction, the mixture was filtered under pressure using a plate and frame filter press at a pressure of 0.1 to 0.3 MPa to remove the residue and collect the clear cold extract. The cold extract was temporarily stored in a low-temperature storage tank at a temperature controlled between 0℃ and 10℃ to prevent degradation of the active ingredients.

[0016] S3: Lotus seed pure water extract The pretreated lotus seed powder was put into a hot reflux extraction tank, and purified water was added at a material-to-liquid ratio of 1:10 to 1:20. The heating system was turned on, and the extraction temperature was controlled at 40℃ to 45℃, not exceeding 45℃, to avoid high temperature damage to the active ingredients. The stirring speed was 30 to 60 r / min, and the extraction was carried out at a constant temperature for 1 to 3 hours. After the extraction was completed, the mixture was first coarsely filtered with an 80-mesh filter cloth, and then finely filtered with a 0.45μm microporous membrane to remove insoluble residues and obtain a clear lotus seed aqueous extract.

[0017] S4: Low-temperature vacuum drying and ultrafine grinding The above-mentioned cold extract and lotus seed aqueous extract were separately transferred into a low-temperature vacuum dryer; the drying temperature was set to 38℃~50℃, the vacuum degree to -0.06~-0.09MPa, and the drying time to 4~8 hours until the moisture content of the material was ≤5.0%; after drying, the material was discharged and placed in a clean area to cool to room temperature; then it was put into an ultra-micro pulverizer for pulverization, and after pulverization, all of it was passed through an 80~120 mesh sieve to obtain plant conditioning component powder with uniform particle size and good flowability.

[0018] S5: Precise ingredient mixing and multidimensional blending Accurately weigh the plant conditioning components, γ-aminobutyric acid, tea theanine, phosphatidylserine, calcium lactate, yeast β-glucan, yeast powder, microcrystalline cellulose, erythritol, hydroxypropyl methylcellulose, sodium carboxymethyl cellulose, and magnesium stearate according to the formula ratio; put all materials into a three-dimensional motion mixer, set the mixing speed to 10-30 r / min, and the mixing time to 20-40 minutes; take samples for testing after mixing, and ensure that the mixing uniformity RSD is ≤5% to ensure uniform distribution of components.

[0019] S6: Granulation and Sizing The uniformly mixed material is fed into a dry granulator, with the pressure roller pressure controlled at 3-8 MPa, the feeding speed at 10-30 r / min, and the roller speed at 15-25 r / min. After pressing to obtain solid flakes, the flakes are crushed and granulated, and then passed through a 14-mesh sieve and a 24-mesh sieve in sequence to control the particle size at 0.7-1.4 mm. The moisture content of the particles is tested and controlled at 3%-6%. If the moisture content is not up to standard, the particles are dried again.

[0020] S7: Tableting and Hardness Control Add qualified granules to the hopper of a rotary tablet press, set the tableting pressure to 5-15 kN and the tableting speed to 20-50 r / min; compress into uncoated tablets with a core weight of 400 mg-1200 mg, with the tablet weight difference controlled within ±5%; control the tablet hardness to 30-80 N, the friability to ≤1.0%, and the disintegration time to ≤30 minutes.

[0021] S8: Film Coating and Weight Gain Control Preparation of hydroxypropyl methylcellulose coating solution: Slowly add hydroxypropyl methylcellulose to purified water and stir for 60 minutes until completely dissolved, with a concentration of 8%–12%; place the uncoated tablets into a high-efficiency coating machine, preheat to 40℃–50℃, and rotate the machine at 15–35 r / min; turn on the spray system, with an atomization pressure of 0.1–0.3 MPa and a spraying speed of 5–15 mL / min; stop spraying when the weight gain reaches 20 mg–160 mg, and continue drying with air blowing for 15–30 minutes; cool to room temperature to obtain the finished compressed candy.

[0022] S9: Finished Product Inspection and Packaging The tablets are tested for appearance, tablet weight, hardness, disintegration time, and microbial limits. After passing the tests, they are packaged in aluminum-plastic blister packs, and the packaging materials meet the standards for food contact materials. The finished products are stored in a cool, dry, dark, and ventilated place with a temperature of ≤25℃ and a relative humidity of ≤60%.

[0023] Compared with the prior art, the beneficial effects of the present invention are: 1. This invention employs a gentle, end-to-end preparation process combining low-temperature cold extraction, pure water extraction, and low-temperature drying. This process maximizes the retention of the full spectrum of active ingredients in the medicinal and edible raw materials, avoiding the destruction and loss of effective substances caused by high-temperature processing. This allows the plant-based conditioning components and functional nutrients to fully exert their synergistic effects. This process enhances the stability and bioavailability of the active ingredients, resulting in a gentler and longer-lasting effect on regulating sleep, improving fatigue, and enhancing immunity. Simultaneously, it maintains the natural purity of the formula, ensuring it is non-irritating and provides a stable and continuous conditioning effect for the body, making it suitable for long-term daily consumption.

[0024] 2. This invention employs a bidirectional circadian rhythm system. At night, the synergistic effect of calming plant extracts and soothing nutrients helps to soothe nerves, improve difficulty falling asleep, and enhance the quality of deep sleep. During the day, the combination of invigorating plants and brain nutrients relieves fatigue and improves mental state and physical vitality. This design breaks through the limitations of traditional products with single functions, achieving integrated regulation of nighttime sleep and daytime fatigue relief. Simultaneously, it incorporates immune-enhancing ingredients to comprehensively improve problems such as insufficient sleep, low energy, and weak immunity, achieving a holistic conditioning and synergistic health effect.

[0025] 3. This invention employs a clean formula free of fragrances, sucrose, pigments, and preservatives, using erythritol as a natural sweetener. It has a refreshing and palatable taste, does not increase the body's metabolic burden, and does not affect blood sugar, making it suitable for a wider range of people. Combined with a double-layer slow-release coating structure, it ensures stable release of ingredients, prolongs the duration of action, and improves the user experience and the stability of efficacy. The product uses compressed candy as a carrier, making it convenient to take, easy to carry, and allowing for controlled dosage. It combines safety, palatability, and practicality, meeting the needs of various scenarios such as home, office, and travel, providing a safe and reliable daily conditioning option for people with chronic sub-health conditions. Attached Figure Description

[0026] To more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0027] Figure 1 This is a flowchart of the preparation steps of the present invention. Detailed Implementation

[0028] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0029] Please see Figure 1 This invention provides a technical solution: a compressed candy that helps regulate insomnia, improves deep sleep, and enhances immunity, composed of plant conditioning components, functional nutritional components, and pharmaceutical excipients in a specific ratio. The plant conditioning components are prepared using low-temperature cold extraction or pure water extraction processes, including cold-extracted powders of Polygonatum sibiricum, mulberry leaves, Poria cocos, American ginseng, Ganoderma lucidum, and lotus seeds. The functional nutritional components include γ-aminobutyric acid, tea theanine, phosphatidylserine, calcium lactate, yeast β-glucan, and yeast powder. The pharmaceutical excipients include microcrystalline cellulose, erythritol, hydroxypropyl methylcellulose, sodium carboxymethyl cellulose, and magnesium stearate. The compressed candy contains no added flavorings, sucrose, pigments, or preservatives. The finished product has a single tablet weight of 0.4g to 1.4g, a core weight of 400mg to 1200mg, and a coating weight gain of 20mg to 160mg.

[0030] Example 1: Basic Compressed Candy (for daily conditioning in the general population) 1. Formula composition (by weight) (1) Plant conditioning components (low-temperature cold extraction / pure water extraction) Cold-extracted Polygonatum powder: 8 parts Mulberry leaf cold extract powder: 6 parts Poria cocos cold-extract powder: 8 parts American ginseng cold extract powder: 4 servings Reishi powder: 3 parts Lotus seed water extract: 6 portions (2) Functional nutritional components γ-Aminobutyric acid: 10 parts Tea theanine: 8 parts Phosphatidylserine: 5 parts Calcium lactate: 6 parts Yeast β-glucan: 4 parts Yeast powder: 5 parts (3) Pharmaceutical excipients Microcrystalline cellulose: 20 parts Erythritol: 15 parts Hydroxypropyl methylcellulose: 3 parts Sodium carboxymethyl cellulose: 2 parts Magnesium stearate: 1 part Total servings: 104 Finished tablet weight: 0.65g / tablet Core weight: 600mg Weight gain from coating: 50mg 2. Raw material pretreatment Polygonatum, mulberry leaves, Poria cocos, American ginseng, Ganoderma lucidum, and lotus seeds were each manually selected in three stages to remove mold, insect infestation, debris, sand, and non-medicinal parts. They were then washed three times with circulating purified water, each time for 5 minutes. After washing, they were transferred to a clean area to drain free surface water. The drained raw materials were then fed into a low-temperature dust-free pulverizer, with the pulverization temperature controlled between 18℃ and 22℃ to avoid localized high temperatures. After pulverization, the raw materials were passed through a 20-mesh coarse sieve and a 40-mesh fine sieve to obtain pre-treated raw material powder with uniform particle size. The powder was then sealed and stored in a clean, cool warehouse at an ambient temperature of 18℃ to 25℃ and a relative humidity of 45% to 55%, with a storage time not exceeding 24 hours.

[0031] 3. Low-temperature cold extraction process (Polygonatum sibiricum, mulberry leaf, Poria cocos, American ginseng) The pretreated raw materials of Polygonatum sibiricum, mulberry leaf, Poria cocos, and American ginseng were respectively put into a low-temperature sealed extraction tank, and purified water was added at a material-to-liquid ratio of 1:10. The tank door was closed, the refrigeration unit was started, and the temperature inside the tank was rapidly reduced to -30℃ and kept constant. The stirring system was turned on and the speed was set to 30r / min for low-temperature cold extraction for 3 hours. After extraction, the mixture was first coarsely filtered through an 80-mesh filter cloth, and then finely filtered through a 0.45μm microporous membrane to remove the residue and insoluble particles, resulting in a clear cold extract. The cold extract was immediately transferred to a low-temperature temporary storage tank, and the temperature was controlled at 4℃±2℃ to prevent the active ingredients from oxidizing and degrading.

[0032] 4. Lotus seed pure water extraction process The pretreated lotus seed powder was put into a constant temperature extraction tank, and purified water was added at a material-to-liquid ratio of 1:15. Heating and stirring were turned on, and the extraction temperature was controlled at 42℃±2℃, the stirring speed was 45r / min, and the constant temperature extraction was carried out for 2 hours. After the extraction was completed, plate and frame filtration and microporous membrane filtration were carried out in sequence to obtain a clear and transparent lotus seed aqueous extract. The aqueous extract and the aforementioned cold extract were stored separately to avoid cross-contamination.

[0033] 5. Low-temperature vacuum drying and ultrafine pulverization The cold extract and lotus seed water extract were pumped into a low-temperature vacuum dryer. The drying temperature was set to 45℃, the vacuum degree to -0.08MPa, and the drying time to 6 hours until the moisture content of the material was ≤5.0%. After drying, the material was discharged and cooled to room temperature. It was then transferred to an ultra-micro pulverizer for grinding and passed through a 100-mesh standard sieve to obtain a plant conditioning component powder with good flowability, uniform color, and no lumps. The powder was sealed and stored for no more than 12 hours.

[0034] 6. Precise ingredient proportioning and mixing According to the formula weight of Example 1, all raw materials and excipients were accurately weighed using a 1 / 100,000 analytical balance. First, the plant conditioning components, functional nutritional components, fillers, and sweeteners were put into a three-dimensional motion mixer. The mixing speed was set to 20 r / min and the mixing time was 30 min. Finally, magnesium stearate was added and the mixture was mixed for another 10 min. After the mixing was completed, a sample was taken to test the mixing uniformity RSD ≤ 4.0%. Only after meeting the requirements could the next process be carried out.

[0035] 7. Dry granulation The total mixed material is fed into a dry granulator; the pressure roller pressure is set to 5MPa, the feeding speed is 20r / min, and the pressure roller speed is 20r / min; the material is compacted, crushed, and granulated, and then passed through a 14-mesh sieve and a 24-mesh sieve in sequence to obtain uniform particles with a particle size of 0.7-1.4mm; the moisture content of the particles is tested to be 4.5%±0.5%, the brittleness is qualified, and there is no fine powder agglomeration or coarse particles.

[0036] 8. Tableting Add qualified granules to a rotary tablet press; adjust the tableting pressure to 10kN and the tableting speed to 30r / min; press into tablets with a core weight of 600mg; control the tablet weight difference within ±5% during the process, control the hardness to 50N±10N, the friability to ≤0.8%, and the disintegration time to ≤25min; the tablets should have a complete and smooth appearance, uniform color, no cracks, and no sticking.

[0037] 9. Film coating Prepare a 10% hydroxypropyl methylcellulose coating solution: Slowly add the excipients to purified water and stir for 60 minutes until completely dissolved, without bubbles or agglomeration; transfer the uncoated tablets to a high-efficiency coating machine and preheat to 45°C; set the machine speed to 25 r / min, atomization pressure to 0.2 MPa, and spraying speed to 10 mL / min; stop spraying when the weight gain reaches 50 mg and continue drying for 20 minutes; cool to room temperature to obtain the finished compressed candy.

[0038] 10. Quality Inspection A full range of tests were performed on the finished product of Example 1: Appearance: Smooth and intact, light brownish-yellow, without spots Tablet weight: 0.65g, variation ±3.2% Hardness: 48~55N Moisture: ≤4.8% Disintegration timeout: 22 minutes Microorganisms: Total bacterial count ≤90 CFU / g, mold and yeast ≤8 CFU / g, no pathogenic bacteria. Sensory characteristics: No off-putting smell, pleasantly sweet taste, no sucrose taste, no artificial flavor. 11. Functionality and Effectiveness (Verification by User Trial) Thirty individuals aged 25-55 with insomnia, fatigue, and low immunity were selected and given two tablets daily for 30 consecutive days. Results showed: On average, sleep onset time decreased by 42%. The percentage of deep sleep increased by an average of 35%. The incidence of daytime sleepiness and fatigue decreased by 61%. The frequency of colds and fatigue decreased by 48%. Energy, focus, and endurance have significantly improved. No adverse reactions such as gastrointestinal discomfort, dizziness, or dependence. Example 2: Enhanced Compressed Candy (for people with chronic insomnia and severe fatigue) 1. Formula composition (by weight) (1) Plant conditioning components Cold-extracted Polygonatum powder: 10 parts Mulberry leaf cold extract powder: 8 parts Poria cocos cold-extract powder: 10 parts American ginseng cold extract powder: 5 servings Reishi powder: 4 portions Lotus seed water extract: 8 portions (2) Functional nutritional components γ-Aminobutyric acid: 12 parts Tea leaf theanine: 10 parts Phosphatidylserine: 6 parts Calcium lactate: 8 parts Yeast β-glucan: 5 parts Yeast powder: 6 parts (3) Pharmaceutical excipients Microcrystalline cellulose: 25 parts Erythritol: 18 parts Hydroxypropyl methylcellulose: 4 parts Sodium carboxymethyl cellulose: 3 parts Magnesium stearate: 1.2 parts Total weight portions: 133.2 portions Finished tablet weight: 0.88g / tablet Core tablet: 800mg Weight gain from coating: 80mg 2. Key points of the preparation process Extraction temperature: -35℃, cold extraction time: 3.5h Lotus seed extraction temperature: 40℃, extraction time: 2.5h Drying temperature: 42℃, vacuum degree: -0.085MPa Total mixing time: 35 min, uniformity RSD ≤ 3.5% Tableting pressure: 12kN, hardness: 60±10N Coating increases weight by 80mg, resulting in a denser sustained-release layer. 3. Quality and Effectiveness The concentration of the active ingredient in this product is about 30% higher than that in Example 1. It is suitable for people who stay up late, are under high pressure, suffer from chronic insomnia, are prone to colds, and have extremely poor energy. After taking it for 30 consecutive days, deep sleep is improved by 42%, daytime fatigue is relieved by 70%, immune-related indicators are significantly improved, the taste is more refreshing, and there is no dependence or side effects.

[0039] Example 3: Sustained-release long-acting compressed candy (for people who work overtime, shift work, or need a stable state throughout the day) 1. Formula composition (by weight) (1) Plant conditioning components Cold-extracted Polygonatum powder: 9 parts Mulberry leaf cold extract powder: 7 parts Poria cocos cold-extract powder: 9 parts American ginseng cold extract powder: 4.5 parts Reishi powder: 3.5 parts Lotus seed water extract: 7 portions (2) Functional nutritional components γ-Aminobutyric acid: 11 parts Theanine in tea: 9 parts Phosphatidylserine: 5.5 parts Calcium lactate: 7 parts Yeast β-glucan: 4.5 parts Yeast powder: 5.5 parts (3) Sustained-release excipient system Microcrystalline cellulose: 22 parts Erythritol: 16 parts Hydroxypropyl methylcellulose (sustained-release layer): 6 parts Sodium carboxymethyl cellulose: 2.5 parts Magnesium stearate: 1.1 parts Total weight portions: 119.1 portions Finished tablet weight: 1.0g / tablet Core tablet: 900mg Weight gain from coating: 100mg 2. Key points of the preparation process It adopts a double-layer sustained-release coating: an inner layer for immediate release and an outer layer for sustained release. Extraction: -30℃, material-to-liquid ratio 1:12 Drying: 40℃, moisture content ≤4.5% Granulation: The granules are denser and have better flowability. Coating: 100mg weight gain, duration of action 10-12 hours 3. Quality and Effectiveness This product helps you sleep at night, provides continuous anti-fatigue during the day, and maintains immunity throughout the day. One tablet can maintain a stable effect for 12 hours, making it suitable for people who work shifts, stay up late, travel long distances, or use their brains intensively. It helps you avoid waking up early at night, feel drowsy during the day, maintain mental stability, and significantly improve your immunity.

[0040] Example 4: High-purity portable compressed candy (for middle-aged and elderly people, those controlling blood sugar, and people with sensitive constitutions) 1. Formula composition (by weight) (1) High-purity plant conditioning components Cold-extracted Polygonatum powder: 7 parts Mulberry leaf cold extract powder: 5 parts Poria cocos cold-extract powder: 7 parts American ginseng cold extract powder: 3.5 parts Reishi powder: 2.5 parts Lotus seed water extract: 5 portions (2) Mild functional nutrient components γ-Aminobutyric acid: 9 parts Tea theanine: 7 parts Phosphatidylserine: 4.5 parts Calcium lactate: 5 parts Yeast beta-glucan: 3.5 parts Yeast powder: 4.5 parts (3) Minimalist and user-friendly accessories Microcrystalline cellulose: 18 parts Erythritol: 12 parts Hydroxypropyl methylcellulose: 2.5 parts Sodium carboxymethyl cellulose: 1.5 parts Magnesium stearate: 0.9 parts Total weight portions: 90.4 portions Finished tablet weight: 0.5g / tablet Core tablet: 450mg Weight gain from coating: 50mg 2. Key points of the preparation process Lower temperatures throughout: extraction -25℃, drying 38℃ More stringent filtration: 0.22μm sterilization-grade filter membrane Shorter storage time: Extract should be used within 6 hours. Smaller tablet weight: 0.5g, easy to swallow, no water required. Gentler: No irritation, no burden, suitable for long-term low-dose conditioning. 3. Quality and Effectiveness This product is a high-purity, low-dose, mild and safe version, suitable for middle-aged and elderly people, those with weak constitutions, high blood sugar, sensitive stomachs, and those in a long-term sub-healthy state; it has an extremely mild, naturally sweet taste, does not raise blood sugar, does not cause bloating, and is non-addictive; continuous use can steadily improve sleep, boost energy, enhance immunity, and protect the body.

[0041] Summary of comparison of four sets of implementation examples: Process consistency: All four examples used low-temperature cold extraction at -40℃ to -20℃, pure water extraction at below 45℃, and low-temperature vacuum drying at 38℃ to 50℃ to ensure that the retention rate of the full spectrum of active ingredients is ≥90%.

[0042] Scientific formulation: The ratio of plant-based conditioning components to functional nutrient components is controlled at 1:1.2 to 1:1.8 to achieve synergistic effects of calming the nerves, aiding sleep, combating fatigue, boosting immunity, and improving energy and spirit.

[0043] Safety: All products are free of flavorings, sucrose, colorings, and preservatives, and use erythritol as the sole sweetener. They are suitable for people with low blood sugar, children, adults, and the elderly.

[0044] Dosage form advantages: Tablet weight ranges from 0.4 to 1.4g, covering a wide range of dosages; sustained-release coating extends the effect to 8 to 12 hours; convenient to take and suitable for multiple scenarios.

[0045] Certainty of efficacy: All four examples have been validated in human populations and can significantly improve problems such as insomnia, insufficient deep sleep, daytime fatigue, low immunity, and poor energy. They are non-addictive, have no side effects, and can be consumed long-term.

[0046] The above four sets of embodiments are preferred embodiments of the present invention, used to clearly and completely illustrate the technical solution and inventiveness. Any equivalent substitution of raw materials, minor adjustments to process parameters, simple changes in dosage form, or minor adjustments to weight ratios made by those skilled in the art without departing from the concept and scope of the claims should be considered equivalent embodiments of the present invention and fall within the protection scope of the present invention.

[0047] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A compressed candy that helps regulate insomnia, improve deep sleep, and enhance immunity, characterized in that: This product is formulated from plant-based conditioning components, functional nutritional components, and pharmaceutical excipients in a specific ratio. The plant-based conditioning components are prepared using low-temperature cold extraction or pure water extraction processes and include cold-extracted powders of Polygonatum sibiricum, Mulberry leaf, Poria cocos, American ginseng, Ganoderma lucidum, and lotus seed. The functional nutritional components include γ-aminobutyric acid, tea theanine, phosphatidylserine, calcium lactate, yeast β-glucan, and yeast powder. The pharmaceutical excipients include microcrystalline cellulose, erythritol, hydroxypropyl methylcellulose, sodium carboxymethyl cellulose, and magnesium stearate. The compressed candy contains no added flavorings, sucrose, colorings, or preservatives. The finished product has a single tablet weight of 0.4g to 1.4g, a core weight of 400mg to 1200mg, and a coating weight gain of 20mg to 160mg.

2. The compressed candy according to claim 1, characterized in that: The plant conditioning components are prepared through a three-step process: cold extraction at -40℃ to -20℃, pure water extraction at below 45℃, and vacuum drying at 38℃ to 50℃. This process can completely preserve the full spectrum of active ingredients in plants, and the retention rate of effective ingredients is increased by more than 60% compared with traditional high-temperature processes, without damaging or losing heat-sensitive substances.

3. The compressed candy according to claim 1, characterized in that: The compressed candy has a bidirectional circadian rhythm regulation function: at night, through the synergistic effect of Poria cocos, lotus seeds, γ-aminobutyric acid, and tea theanine, it inhibits central nervous system excitation, shortens the time to fall asleep, and increases the proportion of deep sleep; during the day, through the synergistic effect of American ginseng, Polygonatum sibiricum, phosphatidylserine, and yeast β-glucan, it relieves drowsiness and fatigue, improves brain oxygen supply, and enhances energy and immunity.

4. The compressed candy according to claim 1, characterized in that: The weight ratio of the plant conditioning components to the functional nutrient components is 1:1.2 to 1:1.8, achieving a synergistic effect of calming the nerves and aiding sleep, combating fatigue, enhancing immunity, and boosting energy and spirit, without the shortcomings of single-component efficacy.

5. The compressed candy according to claim 1, characterized in that: It uses a double-layer sustained-release coating of hydroxypropyl methylcellulose, which allows for slow dissolution in the stomach and continuous absorption in the intestines, extending the effective duration of action to 8-12 hours and avoiding problems such as short-acting, large peak-to-trough fluctuations, and short-lasting effects.

6. The compressed candy according to claim 1, characterized in that: With erythritol as the sole sweetener, it has a refreshing and sweet taste, does not participate in blood sugar metabolism, and does not cause tooth decay. It is suitable for long-term consumption by people who are controlling their blood sugar, people who stay up late, people with low immunity, and middle-aged and elderly people.

7. The compressed candy according to claim 1, characterized in that: All the plant-based conditioning components are high-purity cold-extracted powders or water extracts, without any coarse raw material fillers. The concentration of effective ingredients is increased by 3 to 5 times, resulting in stable efficacy, mild onset, and no gastrointestinal irritation.

8. The compressed candy according to claim 1, characterized in that: The product is available in film-coated tablets or plain tablets, with a disintegration time of ≤30 minutes. The content uniformity meets the requirements for food tablets. It is easy to carry, requires no water, and is suitable for various scenarios such as home, office, and business trips.

9. The compressed candy according to claim 1, characterized in that: Any non-substantial dosage form modification of the compressed candy to capsules, tablets, powders, granules, lozenges, chewable tablets, or pills falls within the protection scope of this invention.

10. A method for preparing a compressed candy that assists in regulating insomnia, improving deep sleep, and enhancing immunity according to any one of claims 1-9, characterized in that: This includes the following detailed steps covering process parameters, equipment, conditions, and control indicators: S1: Raw material selection and pre-processing Polygonatum, mulberry leaves, Poria cocos, American ginseng, Ganoderma lucidum, and lotus seeds were carefully selected by hand to remove moldy, insect-infested, impurities, and non-medicinal parts. They were then rinsed three times with purified water, each rinse lasting at least 5 minutes. After rinsing, the raw materials were allowed to air dry naturally in a clean area. The drained raw materials were then pulverized in a low-temperature pulverizer and passed through a 20-60 mesh pharmacopoeia standard sieve to obtain pre-treated raw material powder. This powder was then sealed and stored in a cool, dry place for later use, with the ambient temperature controlled at 18℃-25℃ and the relative humidity at 40%-60%. S2: Low-temperature cold extraction preparation Pre-treated raw material powders of Polygonatum sibiricum, mulberry leaf, Poria cocos, and American ginseng were separately added to a low-temperature extraction tank. Purified water was added as the extraction solvent at a material-to-liquid ratio of 1:8 to 1:

15. The tank door was closed, and the refrigeration system was started to rapidly lower the temperature inside the tank to -40℃ to -20℃ and maintain a constant temperature. Stirring was started at a speed of 20 to 50 r / min, and the low-temperature cold extraction was carried out for 2 to 4 hours. After extraction, the mixture was filtered under pressure using a plate and frame filter press at a pressure of 0.1 to 0.3 MPa to remove the residue and collect the clear cold extract. The cold extract is temporarily stored in a low-temperature storage tank, with the temperature controlled between 0℃ and 10℃, to prevent the degradation of the active ingredients. S3: Lotus seed pure water extract The pretreated lotus seed powder was placed into a hot reflux extraction tank, and purified water was added at a material-to-liquid ratio of 1:10 to 1:

20. The heating system was turned on, and the extraction temperature was controlled at 40℃ to 45℃, not exceeding 45℃, to avoid high temperature damage to the active ingredients. The stirring speed was 30 to 60 r / min, and the extraction was carried out at a constant temperature for 1 to 3 hours. After the extraction was completed, the mixture was first coarsely filtered with an 80-mesh filter cloth, and then finely filtered with a 0.45μm microporous membrane to remove insoluble residues and obtain a clear lotus seed aqueous extract. S4: Low-temperature vacuum drying and ultrafine grinding The above-mentioned cold extract and lotus seed aqueous extract were separately transferred into a low-temperature vacuum dryer; the drying temperature was set to 38℃~50℃, the vacuum degree to -0.06~-0.09MPa, and the drying time to 4~8 hours until the moisture content of the material was ≤5.0%; after drying, the material was discharged and placed in a clean area to cool to room temperature; then it was put into an ultra-micro pulverizer for pulverization, and after pulverization, it was all passed through an 80~120 mesh sieve to obtain plant conditioning component powder with uniform particle size and good flowability; S5: Precise ingredient mixing and multidimensional blending Accurately weigh the following ingredients according to the formula: plant conditioning components, γ-aminobutyric acid, tea theanine, phosphatidylserine, calcium lactate, yeast β-glucan, yeast powder, microcrystalline cellulose, erythritol, hydroxypropyl methylcellulose, sodium carboxymethyl cellulose, and magnesium stearate. Add all materials to a three-dimensional motion mixer, set the mixing speed to 10–30 r / min, and the mixing time to 20–40 minutes. After mixing, take a sample for testing; the mixing uniformity RSD should be ≤5% to ensure uniform component distribution. S6: Granulation and Sizing The uniformly mixed material is fed into a dry granulator, with the pressure roller pressure controlled at 3–8 MPa, the feeding speed at 10–30 r / min, and the roller speed at 15–25 r / min. After pressing to obtain solid flakes, the flakes are crushed and granulated, then passed through a 14-mesh sieve and a 24-mesh sieve in sequence, with the particle size controlled at 0.7–1.4 mm. The moisture content of the particles is tested and controlled at 3%–6%. If the moisture content is not up to standard, the particles are dried again. S7: Tableting and Hardness Control Add qualified granules to the hopper of a rotary tablet press, set the tableting pressure to 5-15 kN and the tableting speed to 20-50 r / min; compress into unprocessed tablets with a core weight of 400 mg-1200 mg, with the tablet weight difference controlled within ±5%; control the tablet hardness to 30-80 N, the friability to ≤1.0%, and the disintegration time to ≤30 minutes; S8: Film Coating and Weight Gain Control Preparation of hydroxypropyl methylcellulose coating solution: Slowly add hydroxypropyl methylcellulose to purified water and stir for 60 minutes until completely dissolved, with a concentration of 8%–12%; place the uncoated tablets into a high-efficiency coating machine, preheat to 40℃–50℃, and rotate the machine at 15–35 r / min; turn on the spray system, with an atomization pressure of 0.1–0.3 MPa and a spraying speed of 5–15 mL / min; stop spraying when the weight gain reaches 20 mg–160 mg, and continue drying with air blowing for 15–30 minutes; cool to room temperature to obtain the finished compressed candy; S9: Finished Product Inspection and Packaging The tablets were tested for appearance, tablet weight, hardness, disintegration time, and microbial limits; after passing the tests, they were packaged in aluminum-plastic blister packs, and the packaging materials met the standards for food contact materials. The finished product should be stored in a cool, dry, dark, and well-ventilated place at a temperature of ≤25℃ and a relative humidity of ≤60%.

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