Micron controllable micro-injury ultrasonic focusing treatment device

Abstract

The application discloses a kind of micron controllable micro-injury ultrasonic focusing treatment equipment, belong to ultrasonic medical equipment technical field, including dot matrix micron ultrasonic focusing transducer module, adaptive adjustment module, three-dimensional dot matrix global coverage control module, local micro-injury temperature control and safety monitoring module, it can also include coupling and cooling module, one-key operation module, host control module, the core innovation point is in that high-pressure cabin closed structure is used with resonant cavity type ultrasonic transducer, utilizes pressurized sound transmission medium and cavity resonance to realize micron focal domain high-efficiency energy convergence;Adapt to micron controllable micro-injury vascular pruning therapy, realize full-depth energy uniformity by adaptive adjustment, three-dimensional dot matrix coverage realizes global treatment, and safety monitoring guarantees no necrosis treatment.

Description

Technical Field

[0001] This invention relates to the field of ultrasound medical equipment technology, specifically a micron-level controllable micro-damage focused ultrasound therapy device. Background Technology

[0002] Microcirculatory disorders and tissue degenerative changes are the core mechanisms that cause aging, chronic ischemic diseases, and visceral dysfunction. At present, clinical treatment mainly relies on drugs to dilate blood vessels or conventional physical therapy, which are passive improvements and cannot achieve active structural regeneration of the vascular network.

[0003] Existing focused ultrasound (FUS) devices mostly use millimeter-level focal points, primarily targeting thermal ablation and tissue necrosis. Their fixed energy output cannot compensate for attenuation based on tissue depth, leading to easy burns on superficial tissues and insufficient energy at deeper sites. Furthermore, current technologies do not incorporate vascular pruning and regeneration mechanisms, lacking effective solutions for activating immunity and promoting angiogenesis through controllable micro-injury. They also lack modular system design, resulting in high operational barriers and poor adaptability, making it difficult to meet the needs of primary healthcare and various clinical scenarios. In addition, existing ultrasound transducers have limited energy focusing efficiency, failing to stably form a micrometer-level focal zone, hindering precise micro-injury to the vascular endothelial surface and limiting the efficacy and safety of angiogenesis therapy. Summary of the Invention

[0004] The purpose of this invention is to provide a micron-level controllable micro-damage ultrasound focused therapy device to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, the present invention provides the following technical solution:

[0006] A vascular pruning therapy and focused ultrasound treatment device based on controllable micro-trauma includes:

[0007] A matrix-type micron-level ultrasonic focusing transducer module is used to generate micron-level focused ultrasound and achieve precise energy convergence to form a controllable micro-damage focal zone.

[0008] The adaptive adjustment module is used to adaptively adjust the ultrasound power and frequency according to the treatment depth, compensate for tissue attenuation and ensure uniform energy throughout the entire depth.

[0009] The three-dimensional dot matrix full-domain coverage control module is used to drive the transducer to achieve multi-dot matrix synchronous output, covering the treatment area through a three-dimensional structure of points forming surfaces and surfaces forming volumes.

[0010] The local micro-damage temperature control and safety monitoring module is used to monitor the focal zone temperature and tissue status in real time, and to perform safety protection operations when an abnormality is triggered.

[0011] Preferably, the dot-matrix micron-level ultrasonic focusing transducer module includes:

[0012] The transducer unit group contains multiple independently controlled transducer units, which adopt piezoelectric ceramic or capacitive structure, and are used to emit ultrasonic signals and form a dot matrix focused sound field.

[0013] The resonant cavity, located inside the transducer, is used to form standing waves through surface reflection to increase energy density and precisely focus energy to the micron-level focal range;

[0014] The high-pressure chamber is used to seal and contain the pressurized sound transmission medium, providing a stable high-pressure sound transmission environment for the transducer.

[0015] Preferably, the adaptive adjustment module includes:

[0016] A high-frequency power source unit is used to provide an adjustable range of ultrasound emission power to adapt to the energy requirements of different treatment depths;

[0017] The real-time control unit receives treatment depth information and feedback data, and adjusts the power and frequency in real time to achieve uniform energy output across the entire treatment depth range.

[0018] Preferably, the three-dimensional dot matrix full-domain coverage control module includes:

[0019] Piezoelectric ceramic nano-positioning units are used to achieve submicron-level high-precision positioning of transducers;

[0020] Servo robotic arm unit, used to drive transducer to achieve large-range spatial movement;

[0021] The piezoelectric ceramic nano-positioning unit and the servo robotic arm unit work together to drive the transducer to scan along a preset dot matrix trajectory, achieving full three-dimensional coverage of the treatment area in terms of points, surfaces, and cubic dimensions, with the scanning step distance matching the distance between treatment points.

[0022] Preferably, the local micro-damage temperature control and safety monitoring module includes:

[0023] The ultrasound detection unit is used to acquire anatomical images of the target area and locate the target area.

[0024] The photoacoustic imaging unit is used to display the focal zone distribution and tissue status in real time, and works with the ultrasonic detection unit to achieve high-precision target area positioning.

[0025] The high-speed data acquisition unit is used to collect real-time data on focal zone temperature, tissue strain, and acoustic impedance, and feeds this data back to the host control module to trigger power adjustment or shutdown protection.

[0026] Preferably, the device further includes a coupling and cooling module, which provides a stable ultrasonic transmission medium, reduces the temperature of the device and the coupling medium, protects the skin in the treatment area, reduces acoustic attenuation during ultrasonic propagation, and ensures stable operation of the device.

[0027] Preferably, the device also includes a one-button operation module, which is used to preset parameters for different treatment scenarios and start the fully automatic treatment process of the device, reducing the threshold for device operation and eliminating the need for professional personnel to perform precise dissection and positioning.

[0028] Preferably, the device further includes a host control module, which is electrically connected to the dot matrix micron-level ultrasonic focusing transducer module, the adaptive adjustment module, the three-dimensional dot matrix full-domain coverage control module, the local micro-damage temperature control and safety monitoring module, and the one-button operation module, to coordinate the collaborative work of each module and realize the overall operation and status monitoring of the device.

[0029] Compared with the prior art, the beneficial effects of the present invention are:

[0030] Extremely high precision: Through the synergy of the resonant cavity and the high-voltage sound transmission medium, a micron-level focal zone is achieved. Combined with the full coverage of the three-dimensional dot matrix, it accurately acts on the target area, forming only reversible micro-damage without destroying normal tissue, thus solving the problems of excessively coarse focal zones and uncontrollable damage in existing equipment.

[0031] Full-depth adaptation: The adaptive adjustment module dynamically matches power and frequency according to the treatment depth, compensates for tissue attenuation, and achieves uniform treatment across the entire depth from 0.5 to 25 cm, eliminating the pain points of superficial burns and insufficient deep energy.

[0032] Safety closed-loop protection: The local micro-damage temperature control and safety monitoring module collects multi-dimensional data in real time and triggers the protection mechanism, eliminating the risk of tissue necrosis, carbonization, and bleeding throughout the process, making it significantly safer than traditional equipment.

[0033] Easy to use and widely applicable: The one-click operation module lowers the barrier to entry, eliminating the need for professional personnel for precise anatomical positioning, making it suitable for primary healthcare and outpatient services, and expanding the scope of treatment applications.

[0034] Multi-scenario adaptability: It can be used in many fields such as skin vascular pruning, anti-aging, ophthalmology, neurosurgery, and visceral repair, and has both vascular regeneration and immune awakening effects, making it widely applicable for treatment.

[0035] Modular and easy to maintain: Each module has a clear division of labor and works together efficiently, which facilitates equipment assembly, debugging, maintenance and upgrades, and reduces production and usage costs. Attached Figure Description

[0036] Figure 1 This is a schematic diagram of the structure of the treatment device in an embodiment of the present invention.

[0037] Figure 2 This is a schematic diagram of the structure of the dot matrix micron-level ultrasonic focusing transducer module in an embodiment of the present invention.

[0038] Figure 3 This is a schematic diagram of the adaptive adjustment module in an embodiment of the present invention.

[0039] Figure 4 This is a schematic diagram of the structure of the three-dimensional dot matrix full-domain coverage control module in an embodiment of the present invention.

[0040] Figure 5 This is a schematic diagram of the structure of the local micro-damage temperature control and safety monitoring module in an embodiment of the present invention. Detailed Implementation

[0041] To make the objectives, technical solutions, and advantages of this invention clearer, the invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the invention.

[0042] The specific implementation of the present invention will be described in detail below with reference to specific embodiments.

[0043] In one embodiment, see Figures 1-5 A micron-level controllable micro-damage focused ultrasound therapy device, comprising:

[0044] The dot matrix micron-level ultrasonic focusing transducer module 2 is used to generate micron-level focused ultrasound and achieve precise energy convergence to form a controllable micro-damage focal zone.

[0045] Adaptive adjustment module 3 is used to adaptively adjust the ultrasound power and frequency according to the treatment depth, compensate for tissue attenuation and ensure uniform energy throughout the entire depth;

[0046] The three-dimensional dot matrix full-domain coverage control module 4 is used to drive the transducer to achieve multi-dot matrix synchronous output, and cover the treatment area through a three-dimensional structure of points forming surfaces and surfaces forming volumes.

[0047] The local micro-damage temperature control and safety monitoring module 5 is used to monitor the focal zone temperature and tissue status in real time, and to perform safety protection operations when an abnormality is triggered.

[0048] The dot-matrix micron-level ultrasound focusing transducer module 2 serves as the core actuator. Through the collaborative design of "pressurized sound transmission medium + resonant cavity 23", it breaks through the bottleneck of traditional ultrasound energy focusing efficiency and accurately forms a micron-level focal zone, laying the hardware foundation for precise micro-damage. The adaptive adjustment module 3 is designed for tissue attenuation characteristics. Through dynamic matching of power and frequency, it solves the industry pain point of "superficial burns and insufficient energy in deep areas" and ensures the consistency of efficacy across the entire treatment depth. The three-dimensional dot-matrix full-domain coverage control module 4 achieves three-dimensional full coverage of "points forming surfaces and surfaces forming volumes", avoiding missed treatments and superimposed damage, and adapting to different treatment areas. The local micro-damage temperature control and safety monitoring module 5 constructs a closed-loop safety guarantee, monitors in real time and triggers protection mechanisms to eliminate risks such as tissue necrosis and thermal damage.

[0049] It should be noted that the dot-matrix micron-level ultrasonic focusing transducer module 2 includes:

[0050] The transducer unit group 22 contains multiple independently controlled transducer units, which adopt piezoelectric ceramic or capacitive structure and are used to emit ultrasonic signals and form a dot matrix focused sound field.

[0051] The resonant cavity 23 is located inside the transducer and is used to form a standing wave through surface reflection to improve energy density and precisely focus energy to the micron-level focal range.

[0052] The high-pressure chamber 21 is used to enclose the pressurized sound transmission medium in a sealed manner, providing a stable high-pressure sound transmission environment for the transducer.

[0053] The transducer unit group 22 adopts a multi-independent control unit design, which can adjust the phase and amplitude to achieve synchronous output of multiple point arrays and ensure the uniformity of the focal area array; the resonant cavity 23, as a key innovative structure, forms standing waves through surface reflection, which greatly improves the energy density and enables the focal area to be accurately focused to the micron level; the high-pressure chamber 21 provides a high-pressure sound transmission environment for the entire transducer, stabilizes the characteristics of the sound transmission medium, avoids focal area shift caused by pressure changes, and improves energy focusing efficiency.

[0054] It should be noted that the adaptive adjustment module 3 includes:

[0055] The high-frequency power source unit 31 is used to provide an adjustable range of ultrasound transmission power to adapt to the energy requirements of different treatment depths;

[0056] The real-time control unit 32 is used to receive treatment depth information and feedback data, and adjust the power and frequency in real time to achieve uniform energy output across the entire treatment depth range.

[0057] The high-frequency power source unit 31 provides a wide range of adjustable power to adapt to the energy requirements of different treatment depths and tissue densities; the real-time control unit 32 serves as the core computing terminal, receiving treatment depth information and feedback data in real time, and dynamically adjusting power and frequency, fundamentally solving the problems of lagging energy regulation and inability to adapt to tissue attenuation in traditional equipment.

[0058] It should be noted that the three-dimensional dot matrix full-domain coverage control module 4 includes:

[0059] The piezoelectric ceramic nano-positioning unit 41 is used to achieve submicron-level high-precision positioning of the transducer;

[0060] Servo robotic arm unit 42 is used to drive the transducer to achieve a wide range of spatial movements;

[0061] The piezoelectric ceramic nano-positioning unit 41 and the servo robotic arm unit 42 are linked together to drive the transducer to scan according to a preset dot matrix trajectory, so as to achieve full three-dimensional coverage of the treatment area in terms of points, surfaces and cubic dimensions, and the scanning step distance is matched with the distance between treatment points.

[0062] The piezoelectric ceramic nano-positioning unit 41 ensures submicron-level precise positioning, solving the problem of insufficient positioning accuracy in traditional platforms; the servo robotic arm unit 42 enables large-scale spatial movement, adapting to the scanning needs of different treatment areas throughout the body; the two work together to form a "high-precision + large-scale" collaborative control, driving the transducer to scan along a preset trajectory, achieving full three-dimensional coverage of points, surfaces, and cubic surfaces, with precise matching between the scanning step distance and the treatment point distance, ensuring that no treatment area is missed or there is any overlapping damage.

[0063] It should be noted that the local micro-damage temperature control and safety monitoring module 5 includes:

[0064] The ultrasound detection unit 51 is used to acquire anatomical images of the target area and locate the target area.

[0065] The photoacoustic imaging unit 53 is used to display the focal zone distribution and tissue status in real time, and works with the ultrasonic detection unit 51 to achieve high-precision target area positioning.

[0066] The high-speed data acquisition unit 52 is used to acquire real-time data on focal zone temperature, tissue strain and acoustic impedance, and feed them back to the host control module 1 to trigger power adjustment or shutdown protection.

[0067] The ultrasound detection unit 51 acquires anatomical images of the target area to clarify the treatment location; the photoacoustic imaging unit 53 displays the focal zone distribution and tissue status in real time, achieving dual precision of "anatomical positioning + focal zone monitoring"; the high-speed data acquisition unit 52 collects multi-dimensional data such as temperature, strain, and acoustic impedance in real time, and feeds them back to the host to trigger the protection mechanism, constructing a closed-loop safety monitoring system for the entire process to eliminate risks such as thermal damage and tissue necrosis.

[0068] It should be noted that the device also includes a coupling and cooling module 6, which is used to provide a stable ultrasonic transmission medium, reduce the temperature of the device and the coupling medium, protect the skin in the treatment area, reduce the sound attenuation during the ultrasonic propagation process, and ensure the stable operation of the device.

[0069] The coupling and cooling module 6 serves as an auxiliary module for stable equipment operation and treatment safety. Its core functions are threefold: first, to provide a stable ultrasonic transmission medium, reduce sound attenuation during ultrasonic propagation, and ensure energy transfer efficiency; second, to reduce the temperature of the equipment and coupling medium, avoid overheating failures, and maintain long-term stable operation; and third, to protect the skin in the treatment area, prevent burns during ultrasonic coupling, and ensure the stability of the high-voltage transmission medium, avoiding changes in transmission characteristics due to temperature variations.

[0070] It should be noted that the device also includes a one-click operation module 7, which is used to preset parameters for different treatment scenarios and start the fully automatic treatment process of the device, reducing the threshold for device operation and eliminating the need for professional personnel to perform precise dissection and positioning.

[0071] Addressing the pain points of existing equipment's high operational threshold and reliance on precise anatomical positioning by professionals, the one-click operation module 7 is designed with two core capabilities: parameter preset and automatic start. The parameter preset unit can preset ultrasound parameters, scanning trajectories, and safety thresholds according to different treatment scenarios (such as superficial, visceral, and severe cases) to achieve personalized adaptation. After receiving the command, the automatic start unit automatically calls up the preset parameters and coordinates with various modules to complete fully automated treatment without the need for precise anatomical positioning by professionals, greatly reducing the operational threshold, improving treatment efficiency, and adapting to primary healthcare and outpatient services.

[0072] It should be noted that the device also includes a host control module 1, which is electrically connected to a dot matrix micron-level ultrasonic focusing transducer module 2, an adaptive adjustment module 3, a three-dimensional dot matrix full-domain coverage control module 4, a local micro-damage temperature control and safety monitoring module 5, and a one-button operation module 7, to coordinate the collaborative work of each module and realize the overall operation and status monitoring of the device.

[0073] In the multi-module collaborative visceral vascular repair treatment, the host control module 1 receives real-time focal domain data from the dot matrix transducer module, power and frequency data from the adaptive adjustment module 3, positioning data from the three-dimensional coverage control module, temperature data from the safety monitoring module, and scene parameters from the one-button operation module 7. Based on the real-time data, it issues unified instructions to coordinate the adaptive adjustment module 3 to dynamically adjust the energy according to the depth, drive the three-dimensional coverage control module to scan accurately, and simultaneously link the protection mechanism of the safety monitoring module to immediately stop the machine if an abnormality occurs. The entire process achieves seamless multi-module collaboration, stable equipment operation, and significantly improved controllability of the treatment process.

[0074] In this embodiment, regarding skin vascular pruning treatment, the various modules of the device operate collaboratively to adapt to superficial skin vascular pruning treatment. The dot-matrix micron-level ultrasound focusing transducer module 2 employs a 1024-channel piezoelectric ceramic transducer unit group 22, with an internal spherical resonant cavity 23 and a high-pressure chamber 21 (hydrostatic pressure 10MPa) to form an 8-15μm focal zone with a positioning accuracy of ±1.5μm. The adaptive adjustment module 3 automatically adjusts the power from 1-20W and the frequency from 12-15MHz according to a skin depth of 0.5-5cm to achieve superficial energy reduction. The three-dimensional dot-matrix full-domain coverage control module 4 uses a piezoelectric ceramic nano-positioning unit 41 (accuracy 0.8μm) and... The servo robotic arm works in tandem, scanning at 2mm point spacing and 15μm step distance to achieve full three-dimensional coverage; the local micro-damage temperature control and safety monitoring module 5 collects data at a frame rate of 30fps with a temperature resolution of 0.1℃, and immediately adjusts the power in case of abnormalities; the coupling and cooling module 6 maintains the coupling temperature at 30±0.5℃ to protect the skin; the one-button operation module 7 selects the "superficial vascular repair" preset, and the host control module 1 coordinates all modules to ultimately achieve vascular repair without bleeding or necrosis. Vascular density increases and local perfusion improves 7-14 days after treatment.

[0075] Regarding visceral vascular repair, this embodiment is suitable for visceral vascular repair at depths of 5-25cm. The dot-matrix micron-level ultrasound focusing transducer module 2 uses a low-frequency transducer unit group 22, and a resonant cavity 23, combined with a 12-15MPa high-pressure chamber 21, to form an 8-15μm focal zone. The adaptive adjustment module 3 automatically increases the power to 20-80W according to the visceral depth, matching the 3-8MHz low-frequency penetration requirement and compensating for deep attenuation. The three-dimensional dot-matrix full-domain coverage control module 4 drives scanning at a 2mm dot pitch, covering the visceral target area. The local micro-damage temperature control and safety monitoring module 5 monitors the focal zone temperature in real time to avoid visceral thermal damage. The coupling and cooling module 6 stabilizes the sound transmission medium. The main control module 1 and the one-button operation module 7 work together to select the "visceral repair" preset. After treatment, the visceral perfusion volume is significantly improved, with no organ damage, bleeding, or other complications.

[0076] Regarding SMAS layer treatment for skin anti-aging, this embodiment is adapted for micro-damage treatment of the SMAS layer. A dot-matrix micron-level ultrasound focusing transducer module 2 forms a 10μm focal zone, precisely targeting the SMAS layer; an adaptive adjustment module 3 adjusts the energy according to skin depth to avoid surface burns; a three-dimensional dot-matrix full-area coverage control module 4 scans at a 2mm dot spacing to achieve three-dimensional full coverage of the SMAS layer; a local micro-damage temperature control and safety monitoring module 5 monitors the temperature in real time to ensure that damage is limited to the SMAS layer; a one-button operation module 7 selects the "skin anti-aging" preset, and the main control module 1 coordinates the operation. After treatment, collagen regeneration is significant, skin firmness is improved, and there are no adverse reactions such as epidermal damage or redness.

[0077] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A micron-level controllable micro-damage focused ultrasound therapy device, characterized in that, The device includes: A matrix-type micron-level ultrasonic focusing transducer module is used to generate micron-level focused ultrasound and achieve precise energy convergence to form a controllable micro-damage focal zone. The adaptive adjustment module is used to adaptively adjust the ultrasound power and frequency according to the treatment depth, compensate for tissue attenuation and ensure uniform energy throughout the entire depth. The three-dimensional dot matrix full-domain coverage control module is used to drive the transducer to achieve multi-dot matrix synchronous output, covering the treatment area through a three-dimensional structure of points forming surfaces and surfaces forming volumes. The local micro-damage temperature control and safety monitoring module is used to monitor the focal zone temperature and tissue status in real time, and to perform safety protection operations when an abnormality is triggered.

2. The micron-level controllable micro-damage focused ultrasound therapy device according to claim 1, characterized in that, The matrix-type micron-level ultrasonic focusing transducer module includes: The transducer unit group contains multiple independently controlled transducer units, which adopt piezoelectric ceramic or capacitive structure, and are used to emit ultrasonic signals and form a dot matrix focused sound field. The resonant cavity, located inside the transducer, is used to form standing waves through surface reflection to increase energy density and precisely focus energy to the micron-level focal range; The high-pressure chamber is used to seal and contain the pressurized sound transmission medium, providing a stable high-pressure sound transmission environment for the transducer.

3. The micron-level controllable micro-damage focused ultrasound therapy device according to claim 1, characterized in that, The adaptive adjustment module includes: A high-frequency power source unit is used to provide an adjustable range of ultrasound emission power to adapt to the energy requirements of different treatment depths; The real-time control unit receives treatment depth information and feedback data, and adjusts the power and frequency in real time to achieve uniform energy output across the entire treatment depth range.

4. The micron-level controllable micro-damage focused ultrasound therapy device according to claim 1, characterized in that, The three-dimensional dot matrix full-domain coverage control module includes: Piezoelectric ceramic nano-positioning units are used to achieve submicron-level high-precision positioning of transducers; Servo robotic arm unit, used to drive transducer to achieve large-range spatial movement; The piezoelectric ceramic nano-positioning unit and the servo robotic arm unit work together to drive the transducer to scan along a preset dot matrix trajectory, achieving full three-dimensional coverage of the treatment area in terms of points, surfaces, and cubic dimensions, with the scanning step distance matching the distance between treatment points.

5. The micron-level controllable micro-damage focused ultrasound therapy device according to claim 1, characterized in that, The local micro-damage temperature control and safety monitoring module includes: The ultrasound detection unit is used to acquire anatomical images of the target area and locate the target area. The photoacoustic imaging unit is used to display the focal zone distribution and tissue status in real time, and works with the ultrasonic detection unit to achieve high-precision target area positioning. The high-speed data acquisition unit is used to collect real-time data on focal zone temperature, tissue strain, and acoustic impedance, and feeds this data back to the host control module to trigger power adjustment or shutdown protection.

6. A micron-level controllable micro-damage focused ultrasound therapy device according to any one of claims 1-5, characterized in that, The device also includes a coupling and cooling module, which provides a stable ultrasonic transmission medium, reduces the temperature of the device and coupling medium, protects the skin in the treatment area, reduces acoustic attenuation during ultrasonic propagation, and ensures stable operation of the device.

7. The micron-level controllable micro-damage focused ultrasound therapy device according to claim 6, characterized in that, The device also includes a one-button operation module, which is used to preset parameters for different treatment scenarios and start the device's fully automatic treatment process, reducing the barrier to entry for device operation and eliminating the need for professional personnel to perform precise anatomical positioning.

8. The micron-level controllable micro-damage focused ultrasound therapy device according to claim 7, characterized in that, The device also includes a host control module, which is electrically connected to a dot matrix micron-level ultrasonic focusing transducer module, an adaptive adjustment module, a three-dimensional dot matrix full-domain coverage control module, a local micro-damage temperature control and safety monitoring module, and a one-button operation module, to coordinate the collaborative work of each module and realize the overall operation and status monitoring of the device.

Images