Use of natural product monomer 3-epiglochidiol in the preparation of wound healing promoters
By using the natural product monomer 3-epiglochidiol to inhibit the expression of TNF-α, IL-6 and p-STAT3 proteins, a topical formulation was prepared, which solved the problems of drug resistance and unstable efficacy of existing wound healing promoters, achieved safe and effective skin wound healing, and expanded its application in the field of wound healing.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- QILU NORMAL UNIV
- Filing Date
- 2026-03-31
- Publication Date
- 2026-07-17
AI Technical Summary
Existing wound healing promoters suffer from problems such as drug resistance, high cost, unstable efficacy, and unclear mechanism of action. Furthermore, the quality control of existing Chinese herbal extracts with unknown components is difficult, and they cannot effectively regulate inflammatory responses.
Using the natural product monomer 3-epiglochidiol as the active ingredient, it promotes skin wound healing by inhibiting the expression of TNF-α, IL-6 and p-STAT3 proteins. It is prepared into topical dosage forms such as ointments, creams, and gels, and is suitable for the treatment or adjuvant treatment of acute and chronic skin wounds.
It significantly inhibits the inflammatory response of skin wounds, promotes the maturation and re-epithelialization of granulation tissue, and achieves safe and effective skin wound healing. It avoids antibiotic resistance and the potential toxicity of chemically synthesized drugs, and is suitable for long-term or local topical use.
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