A natural polymer-based absorbable surgical suture and a method for preparing the same

By controlling the degree of deacetylation of chitin, suture models with different degradation rates were designed. Combined with wet twisting technology and a preparation method without chemical cross-linking agents, the problem of mismatch between suture degradation rate and tissue healing cycle was solved, resulting in sutures with high biocompatibility and mechanical properties suitable for surgical procedures.

CN122399084APending Publication Date: 2026-07-17
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Filing Date
2026-04-27
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing absorbable sutures have uncontrollable degradation rates, making it impossible to accurately match the healing cycles of different tissues, and they also suffer from insufficient biocompatibility and mechanical properties.

Method used

By controlling the degree of deacetylation (DD) of chitin, suture models with different degradation rates were designed. Using natural polymer-based materials, combined with wet twisting technology and a preparation method without chemical cross-linking agents, skin repair and muscle repair sutures were prepared.

Benefits of technology

It achieves a precise match between the suture degradation rate and the tissue healing cycle, improves biocompatibility and mechanical properties, meets surgical standards, and is environmentally friendly.

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Abstract

本发明提供一种天然高分子基可吸收外科手术缝线及其制备方法,其中,缝线的原料为甲壳素或壳聚糖,并且缝线根据目标修复组织的愈合周期被设计为具有不同降解速率的缝线型号,包括:皮肤修复型缝线,其原料的脱乙酰度为45~50%;肌肉修复型缝线,其原料的脱乙酰度为70~75%。该方案有效克服了现有技术中“一刀切”式缝合线的缺陷,在确保高生物安全性和必要力学性能的前提下,真正做到了因组织而异,随时间而解,为外科手术提供了一组兼具创新性与实用性的组织特异性修复材料。
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Citation Information

Patent Citations

  • CN100420488C