A self-curling membrane for peripheral nerve repair and methods of making the same
By preparing self-rolling membranes through drying and rolling in a mold, the self-rolling problem of peripheral nerve repair membranes was solved, achieving efficient production and stability while reducing costs.
Patent Information
- Application Number
- CN202610852150.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-06-12
- Publication Date
- 2026-07-17
AI Technical Summary
Existing peripheral nerve repair films lack self-rolling properties, resulting in cumbersome application steps, difficulty in adhering to nerve fibers, low yield, high manufacturing costs, and inconsistent product stability.
The decellularized extracellular matrix fibrosis solution was leveled and dried in a mold, then rolled and air-dried on a cylindrical mold, and peeled off to obtain a self-curling membrane. The concentration of the fibrosis solution and the drying conditions were controlled, and the membrane was processed using a polytetrafluoroethylene tank and a tungsten carbide rod.
It achieves efficient demolding, with a yield rate close to 100%, reducing production costs. The product has high stability and good performance consistency between the same batch and different batches, making it suitable for peripheral nerve repair.
Smart Images
Figure CN122399113A_ABST