A whitevein peptid with xanthine oxidase inhibitory activity, and a preparation method and application thereof
By hydrolyzing *Cynanchum paniculatum*, *Cynanchum paniculatum* peptides with amino acid sequences of FNW or YGW were obtained and prepared using a solid-phase synthesis method. This method solves the adverse reaction problem of existing xanthine oxidase inhibitors and provides a safe and effective xanthine oxidase inhibitor for the relief of hyperuricemia.
CN122404475APending Publication Date: 2026-07-17LUDONG UNIVERSITY
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Patent Information
- Application Number
- CN202610857586.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-06-15
- Publication Date
- 2026-07-17
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Figure CN122404475A_ABST
Abstract
本发明公开了一种具有黄嘌呤氧化酶抑制活性的白薇肽及其制备方法和应用，属于生物活性肽技术领域。所述白薇肽的氨基酸序列为FNW或YGW。本发明发现并证实了白薇水解物中存在具有黄嘌呤氧化酶抑制活性的多肽成分，其中，氨基酸序列为FNW和YGW的白薇肽能够有效抑制黄嘌呤氧化酶的活性，具有降低尿酸水平的作用，可用于制备缓解高尿酸血症的药物制剂。
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