A method for efficiently separating alpha-lactalbumin in whey
By modifying the polysulfone ultrafiltration membrane to form a polydopamine coating and reacting it in taurine solution, its hydrophilicity and conductivity are improved, solving the problems of low migration rate and insufficient yield of α-lactalbumin in the EDUF system, and achieving efficient and stable separation effect.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- NANKAI UNIV
- Filing Date
- 2026-03-19
- Publication Date
- 2026-07-17
AI Technical Summary
Existing technologies using electrodialysis/ultrafiltration coupling (EDUF) systems to separate α-lactalbumin from whey exhibit low target protein migration rates and insufficient yields. Furthermore, the poor hydrophilicity of the polysulfone ultrafiltration membrane surface leads to membrane fouling and high mass transfer resistance, thus affecting separation efficiency.
By modifying polysulfone ultrafiltration membranes to form a polydopamine coating and reacting it in taurine solution, the hydrophilicity and conductivity of the membrane surface are improved, and the non-specific adsorption of proteins is reduced. The modified membrane is used in the EDUF separation process to improve the migration rate and yield of α-lactalbumin.
The modified polysulfone ultrafiltration membrane significantly improved the migration rate and yield of α-lactalbumin during the EDUF process, reduced membrane surface fouling and mass transfer resistance, and achieved stable operation and efficient separation of the separation process.
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