Application of multiple fungal fluorescent staining solution in preparation of rapid identification of fungal survival / drug resistance kit
By using solutions A and B of multiplex fungal fluorescent staining solution to label fungal cell walls and detect metabolic activity with fluorescent dyes, the problems of long detection time and low sensitivity in fungal drug resistance detection are solved. This enables rapid and accurate identification of fungal survival and drug resistance, and is suitable for rapid diagnosis and treatment of clinical fungal infections.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- GUANGZHOU HANDE ZEXIN PHARM TECH CO LTD
- Filing Date
- 2026-04-30
- Publication Date
- 2026-07-17
AI Technical Summary
Existing technologies for fungal resistance detection suffer from problems such as long processing time, low sensitivity, inability to detect unknown resistance mechanisms, and high false resistance rates due to insufficient specimen quality control.
Multiplex fluorescent staining solutions for fungi, including solution A and solution B, were used. Solution A used fluorescent brighteners and nucleic acid fluorescent dyes that selectively penetrate and damage the cell membrane to label the fungal cell wall. Solution B used metabolically active dyes to rapidly identify the survival status and drug resistance of fungi, which were then observed using a fluorescence microscope.
It enables rapid and accurate identification of fungal survival status and drug resistance, shortens detection time, improves detection accuracy and ease of operation, and is suitable for rapid auxiliary diagnosis and treatment of clinical fungal infections.
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Figure CN122409296A_ABST
Abstract
Citation Information
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