Joint encoding and decoding method based on DNA storage system and related device

By introducing RS-LDPC serial cascade structure and joint decoding scheme into the DNA storage system, the asymmetric error problem in nanopore sequencing is effectively solved, decoding efficiency and error correction capability are improved, and higher data reliability and stability are achieved.

CN122419486APending Publication Date: 2026-07-17SOUTH CHINA NORMAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SOUTH CHINA NORMAL UNIV
Filing Date
2026-04-13
Publication Date
2026-07-17

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Abstract

本申请公开了基于DNA存储系统的联合编码与译码方法及相关设备，方法包括：对待编码的信息序列依次进行RS编码和LDPC编码，得到两个级联码字并配对得到比特对序列；将比特对序列转换为发送碱基序列，进而合成DNA片段；对DNA片段进行纳米孔测序，得到接收碱基序列，将接收碱基序列转换为两个待译码序列，并根据纳米孔测序中碱基间的非对称替代错误特性计算初始对数似然比信息，进而进行迭代译码，得到两个内码译码序列，根据RS译码算法继续译码，得到译码后的信息序列。本申请实施例构建了RS‑LDPC串行级联结构，并设计了相应的联合译码方案，提升了系统整体的译码可靠性与稳定性。本申请可以广泛应用于DNA存储技术领域。
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