Temperature-controllable cell storage bag

By setting up low temperature and temperature regulation mechanisms in the cell storage bag, and using technologies such as liquid nitrogen and cold conduction blocks, the problem of temperature changes in stem cell frozen liquid is solved, and the stable low temperature preservation and efficient temperature regulation of cells are achieved, ensuring cell storage Environmental stability and portability.

CN222322608UActive Publication Date: 2025-01-10ZHONGKE SHENGQUAN (SHANDONG) BIOENGINEERING CO LTD
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Patent Information

Application Number
CN202421062334.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-16
Publication Date
2025-01-10
Estimated Expiration
2034-05-16

AI Technical Summary

Technical Problem

The temperature of the existing stem cell frozen liquid changes over time, affecting the storage status of cells.

Method used

Design a temperature-controllable cell storage bag, including a low-temperature mechanism and a temperature regulation mechanism, and use components such as liquid nitrogen storage tank and cold guide block to realize the low-temperature storage bag and be equipped with a temperature sensor and a monitor for Real-time monitoring.

Benefits of technology

Effectively maintain the low temperature state of cell frozen liquid, improve storage efficiency, ensure the stability of the cell storage environment, and the structure is simple and easy to carry.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a temperature-controllable cell storage bag, which relates to the technical field of cell culture and comprises an outer bag, a partition bag is arranged in the outer bag, a cavity is arranged in the partition bag, a plurality of placing grooves for placing cell cryopreservation bags are arranged on the surface of the partition bag, and the cell cryopreservation bags are placed in the placing grooves. The cell cryopreservation bag further comprises a low-temperature mechanism and a temperature adjusting mechanism, the low-temperature mechanism is arranged on one side of the outer bag and used for conducting low-temperature preservation on the cell cryopreservation bag, and the temperature adjusting mechanism is arranged on the side, away from the low-temperature mechanism, of the outer bag and used for adjusting the internal temperature of the partition bag. The cell cryopreservation device is provided with the low-temperature mechanism, liquid nitrogen is stored through the liquid nitrogen storage tank, so that the cell cryopreservation bag can be subjected to low-temperature preservation treatment in time, the cell cryopreservation bag can be independently stored, the storage state of cells cannot be influenced during sampling, the temperature adjusting mechanism is arranged, the temperature of the partition bag can be adjusted, and the temperature of the liquid nitrogen can be reduced; the storage efficiency is improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of cell culture, in particular to a temperature-controllable cell storage bag. Background Art

[0002] With the rapid development of medical science and technology, people's awareness of the importance of cells has become increasingly obvious, and cell preservation has become increasingly important. For example, a stem cell cryopreservation bag recorded in the patent with patent announcement number CN 215812003 U has a cryopreservation liquid storage bag and a stem cell storage bag respectively arranged on both sides of the partition bag, and a stem cell cryopreservation liquid is injected into the cryopreservation liquid storage bag to form a freezing structure in the bag body, thereby forming an external freezing effect on the stem cell storage bag. However, after a long period of use, the temperature of the stem cell cryopreservation liquid will change, which will affect the storage state of the cells.

[0003] Based on this, a temperature-controllable cell storage bag is now provided to eliminate the disadvantages of existing storage bags. Utility Model Content

[0004] The utility model aims to provide a temperature-controllable cell storage bag to solve the problem in the background art that the temperature of the stem cell freezing solution changes over time and thus affects the cell storage state.

[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0006] A temperature-controllable cell storage bag comprises an outer bag, a partition bag is arranged inside the outer bag, a chamber is arranged inside the partition bag, a surface of the partition bag is provided with a plurality of placement slots for placing cell freezing bags, and also comprises a low-temperature mechanism and a temperature regulating mechanism. The low-temperature mechanism is arranged on one side of the outer bag and is used to store the cell freezing bags at low temperatures. The temperature regulating mechanism is arranged on a side of the outer bag away from the low-temperature mechanism and is used to regulate the internal temperature of the partition bag.

[0007] Preferably, the cryogenic mechanism comprises a fixedly mounted box body, a liquid nitrogen storage tank is arranged inside the box body, the liquid nitrogen storage tank is connected to the spacer bag via a delivery pipe, and a solenoid valve is arranged on the outside of the delivery pipe.

[0008] Preferably, the temperature regulating mechanism comprises a plurality of openings formed on the surface of the outer bag, a cooling block is fixedly installed inside the opening, a cooling fin is arranged on one side of the cooling block, and a radiator is arranged on the side of the cooling fin away from the cooling block.

[0009] Preferably, hand straps are fixedly provided on both sides of the outer bag.

[0010] Preferably, a display is provided on one side of the box.

[0011] Preferably, a liquid outlet is provided on one side of the partition bag, and a liquid outlet pipe is provided at the liquid outlet and extends to the outside of the outer bag.

[0012] Preferably, a temperature sensor is provided inside the compartment bag, and the temperature sensor is electrically connected to the display.

[0013] Preferably, a box door is provided on one side of the box body close to the liquid outlet pipe.

[0014] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0015] 1. The utility model is provided with a low temperature mechanism, and liquid nitrogen is stored in a liquid nitrogen storage tank. With the cooperation of the septum bag, the cell freezing bags can be timely cryopreserved. The cell freezing bags can be stored separately, so that the storage state of the cells will not be affected when sampling;

[0016] 2. The utility model is provided with a temperature regulating mechanism, which can regulate the temperature of the compartment bag through the cooperation between the opening, the cooling block, the cooling sheet, the radiator and the temperature sensor, thereby reducing the temperature of the liquid nitrogen and improving the storage efficiency, and has strong practicality;

[0017] 3. The utility model is provided with a display, so that the temperature sensor can monitor the temperature inside the compartment bag in real time, thereby ensuring the stability of the cell storage environment. It has the advantage of improving the stability of the environment inside the storage bag, has a simple structure, and is provided with a hand strap for easy carrying. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a structural schematic diagram of one side of the utility model.

[0019] Figure 2 It is a structural schematic diagram of the other side of the utility model.

[0020] Figure 3 It is a structural schematic diagram of the utility model.

[0021] Figure 4 It is a schematic diagram of the internal structure of the utility model.

[0022] Figure 5 For the utility model Figure 3 Enlarged view of point A in the middle.

[0023] Notes on the figure numbers: 101, outer bag; 102, partition bag; 103, chamber; 104, cell freezing bag; 105, placement slot; 106, hand strap; 107, display; 108, liquid outlet pipe; 200, low temperature mechanism; 201, box body; 202, liquid nitrogen storage tank; 203, delivery pipe; 204, solenoid valve; 205, box door; 300, temperature adjustment mechanism; 301, opening; 302, cooling block; 303, cooling plate; 304, radiator. DETAILED DESCRIPTION

[0024] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments.

[0025] Example 1

[0026] In this embodiment, if Figure 1-Figure 5 As shown, a temperature-controllable cell storage bag includes an outer bag 101, the outer bag 101 is a heat-insulating material to prevent the rapid loss of liquid nitrogen temperature, a partition bag 102 is arranged inside the outer bag 101, a chamber 103 is arranged inside the partition bag 102, and the chamber 103 is a liquid nitrogen chamber. A plurality of placement grooves 105 for placing cell freezing bags 104 are opened on the surface of the partition bag 102. The placement grooves 105 are consistent with the size of the cell freezing bags 104. The placement grooves 105 can be set to different sizes and are suitable for storing multiple cell freezing bags 104 of different specifications at the same time. It also includes a low temperature mechanism 200 and The temperature regulating mechanism 300 and the low temperature mechanism 200 are arranged on one side of the outer bag 101 and are used to store the cell freezing bags 104 at low temperatures. The temperature regulating mechanism 300 is arranged on the side of the outer bag 101 away from the low temperature mechanism 200 and is used to adjust the internal temperature of the partition bag 102. Before the temperature-controlled cell storage bag is used, first check whether the storage bag can be used normally, then place a number of cell freezing bags 104 in the placement slot 105, operate the low temperature mechanism 200 through the display 107, and inject liquid nitrogen into the partition bag 102, so that the storage bag enters a state of being ready for use;

[0027] Among them Figure 2-Figure 4As shown, the low temperature mechanism 200 includes a fixedly installed box body 201, and the box body 201 plays a protective role for the liquid nitrogen storage tank 202. The box body 201 is provided with a liquid nitrogen storage tank 202 inside, and the liquid nitrogen storage tank 202 is used to store liquid nitrogen to avoid safety accidents. The liquid nitrogen storage tank 202 is connected to the partition bag 102 through a delivery pipe 203, and a pump is provided at one end of the delivery pipe 203 to facilitate the delivery of liquid nitrogen to the inside of the partition bag 102. Liquid nitrogen is filled into the chamber 103 through the delivery pipe 203 to ensure that the temperature in the partition bag 102 remains stable. A solenoid valve 204 is provided on the outside of the delivery pipe 203, and the solenoid valve 204 is electrically connected to the display 107. The delivery amount of liquid nitrogen is controlled by the solenoid valve 204;

[0028] Among them Figure 2-Figure 5 As shown, the temperature regulating mechanism 300 includes a plurality of openings 301 opened on the surface of the outer bag 101, and the openings 301 are in contact with the surface of the compartment bag 102, so that the cooling block 302 can maintain contact with the compartment bag 102, so that the temperature generated by the refrigeration plate 303 can be transmitted to the compartment bag 102, and the liquid nitrogen inside the compartment bag 102 can be quickly cooled and pre-cooled. The cooling block 302 is fixedly installed inside the opening 301, and a cooling plate 303 is arranged on one side of the cooling block 302. The cooling plate 303 is electrically connected to the display 107. By operating the display 107, the user can quickly perform the cooling operation. A radiator 304 is arranged on the side of the cooling plate 303 away from the cooling block 302, and the side of the cooling plate 303 is dissipated by the radiator 304. The radiator 304 is electrically connected to the display 107.

[0029] Among them Figure 1 As shown, both sides of the outer bag 101 are fixedly provided with hand straps 106, which facilitate the user to transport the storage bag, making it portable and increasing the practical effect of the storage bag;

[0030] Among them Figure 2 As shown, a display 107 is provided on one side of the box 201, and the user can observe the temperature inside the compartment bag 102 in real time through the display, so that the temperature adjustment mechanism 300 can be quickly operated to ensure the cell activity inside the cell freezing bag 104;

[0031] Among them Figure 1-Figure 3 As shown, a liquid outlet is provided on one side of the partition bag 102, and a liquid outlet pipe 108 is provided at the liquid outlet and extends to the outside of the outer bag 101. The function of the liquid outlet and the liquid outlet pipe 108 is to facilitate the discharge of liquid nitrogen inside the partition bag 102 when the storage bag is idle, so as to avoid affecting the next use;

[0032] Example 2

[0033] The difference from Example 1 is that Figure 4 As shown, a temperature sensor is provided inside the partition bag 102, and the temperature sensor is electrically connected to the display 107. The temperature sensor monitors the temperature of the liquid nitrogen in the partition bag 102 and transmits the temperature data to the display 107 for display, so that the user can observe the temperature in the partition bag 102 and operate it conveniently;

[0034] Among them Figure 2 and Figure 3 As shown, a box door 205 is provided on one side of the box body 201 close to the liquid outlet pipe 108, and the box door 205 is connected to the box body 201 through a hinge, which facilitates the replacement and maintenance of the liquid nitrogen storage tank 202 and reduces the possibility of safety accidents.

[0035] During use, the user manually operates the display 107 to open the pump and the solenoid valve 204, thereby transporting the liquid nitrogen in the liquid nitrogen storage tank 202 to the chamber 103. The liquid nitrogen transmits the temperature to the surface of the cell freezing bag 104 through the partition bag 102, thereby playing a role in low-temperature preservation. When the temperature sensor inside the partition bag 102 detects that the temperature of the liquid nitrogen has risen, the refrigeration plate 303 and the radiator 304 are started, and the temperature of the liquid nitrogen inside the partition bag 102 is reduced through the cooling block 302, thereby achieving the purpose of temperature control. The operation is relatively simple and the practicability is good.

[0036] The above is only a specific implementation of the present disclosure, but the protection scope of the present disclosure is not limited thereto. Any person skilled in the art who is familiar with the technical field can easily think of changes or substitutions within the technical scope disclosed in the present disclosure, which should be included in the protection scope of the present disclosure. Therefore, the protection scope of the present disclosure should be based on the protection scope of the claims.

Claims

1. A temperature-controllable cell storage bag, comprising an outer bag (101), a partition bag (102) is provided inside the outer bag (101), a chamber (103) is provided inside the partition bag (102), and a plurality of placement grooves (105) for placing cell freezing bags (104) are provided on the surface of the partition bag (102); It is characterized in that It also includes a low temperature mechanism (200), which is arranged on one side of the outer bag (101) and is used to perform low temperature storage on the cell freezing bag (104); A temperature regulating mechanism (300) is arranged on a side of the outer bag (101) away from the low temperature mechanism (200) and is used to regulate the internal temperature of the partition bag (102).

2. The temperature-controllable cell storage bag according to claim 1, characterized in that: The low temperature mechanism (200) comprises a fixedly installed box body (201), a liquid nitrogen storage tank (202) is arranged inside the box body (201), the liquid nitrogen storage tank (202) is connected to the partition bag (102) via a delivery pipe (203), and a solenoid valve (204) is arranged on the outside of the delivery pipe (203).

3. The temperature-controllable cell storage bag according to claim 1, characterized in that: The temperature adjustment mechanism (300) comprises a plurality of openings (301) opened on the surface of the outer bag (101), a cooling block (302) is fixedly installed inside the opening (301), a cooling fin (303) is arranged on one side of the cooling block (302), and a radiator (304) is arranged on the side of the cooling fin (303) away from the cooling block (302).

4. The temperature-controllable cell storage bag according to claim 1, characterized in that: Hand straps (106) are fixedly provided on both sides of the outer bag (101).

5. The temperature-controllable cell storage bag according to claim 2, characterized in that: A display (107) is provided on one side of the box (201).

6. The temperature-controllable cell storage bag according to claim 1, characterized in that: A liquid outlet is provided on one side of the partition bag (102), and a liquid outlet pipe (108) is provided at the liquid outlet and extends to the outside of the outer bag (101).

7. The temperature-controllable cell storage bag according to claim 1, characterized in that: A temperature sensor is disposed inside the partition bag (102), and the temperature sensor is electrically connected to the display (107).

8. The temperature-controllable cell storage bag according to claim 2, characterized in that: A box door (205) is provided on one side of the box body (201) close to the liquid outlet pipe (108).

Citation Information

Patent Citations

  • Stem cell cryopreservation bag

    CN215812003U