Detection device for tear film rupture time
By providing a tear film break-up time detection device including an eye expander, an atomization structure and a collection device, the existing technology problems of difficulty in animal detection and unfavorable anesthesia are solved, an efficient and low-irritation detection process is achieved, and the efficiency is improved Experimental efficiency.
Patent Information
- Application Number
- CN202420467099.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-11
- Publication Date
- 2025-01-21
- Estimated Expiration
- 2034-03-11
AI Technical Summary
In the prior art, it is difficult to detect the time of tear film rupture in animals, and multiple people need to cooperate or anesthetize the experimental animals, resulting in the prolongation of the experimental progress and increasing the difficulty, and multiple anesthesia is not conducive to the detection of other animal indicators.
A tear film break-up time detection device is provided, including an eye expander, an atomization structure and a collection device. The eye expander separates the upper and lower eyelids of the animal through the eye expander bracket. The atomization structure uses the atomization nozzle to evenly spray the fluorescein sodium solution. The acquisition device collects the ocular surface image through the lens to avoid direct stimulation of the eye surface by the solution and reduce animal struggle.
Through the use of this device, the struggle of animals during the detection process is reduced, the need for animal anesthesia is reduced, the detection process is simplified, the experimental efficiency is improved, and the animals can more easily detect other indicators.
Smart Images
Figure CN222367679U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of animal experiments, in particular to a device for detecting tear film breakup time. Background Art
[0002] Tear breakup time is a means of detecting the health of the animal's eye surface. It is mainly used to determine the occurrence of dry eye syndrome and reflects the degree of eye dryness and the quality of the tear film. Fluorescein sodium staining can observe corneal epithelial damage, tear film integrity and detect tear breakup time (TBUT). The tear film detection method is mainly to drop 1% sodium fluorescein solution into the animal's conjunctival sac, wait for 1 minute, and observe and time under the diamond blue light of a slit lamp microscope. The TBUT of the eye surface of the normal group is>10s, while the TBUT of the eye surface of animals with dry eyes and visual fatigue is<5s. The TBUT experiment can not only be used to evaluate the tear film quality and ocular surface health of humans, but also can be used as a detection item for ophthalmic disease model animals, and it is also one of the important detection indicators for dry eye animal models and visual fatigue animal models.
[0003] The existing technology mainly involves dripping fluorescein sodium solution into the human eye or animal eye surface, and then using equipment to perform the test. Humans can cooperate with the test requirements to complete the test well, but experimental animals or pets cannot do the same as humans and will struggle obviously, making the experiment difficult to complete. In particular, large animals require the cooperation of multiple people or anesthesia for the experimental animals or pets, which undoubtedly prolongs the experimental progress and increases the difficulty. In addition, multiple anesthesia is not conducive to the detection of other indicators of animals. Utility Model Content
[0004] Therefore, the technical problem to be solved by the present invention is to overcome the defects in the prior art that animal detection is difficult and anesthetizing animals is not conducive to detecting other indicators of animals, thereby providing a tear film rupture time detection device.
[0005] In order to solve the above problems, the utility model provides a detection device for tear film breakup time, characterized in that it includes: an eye expander, including a barrel and an eye expander support, the opening at the bottom of the barrel is located on the eye expander support, and the eye expander support is suitable for separating the upper and lower eyelids of animals; an atomization structure, including a container and an atomization rod, the first end of the atomization rod is connected to the container, and the second end is suitable for extending into the barrel to near the bottom of the barrel, and the second end of the atomization rod is provided with an atomization nozzle; a collection device, including a lens seat and a lens, the size of the lens seat is larger than the radial size of the barrel, and is suitable for overlapping the top of the barrel, and the lens is located at a position where the lens seat faces the inside of the barrel.
[0006] Optionally, the eye-expanding bracket includes a first scissor arm and a second scissor arm hinged together, and a first eye support and a second eye support respectively located at the bottom of the first scissor arm and the second scissor arm.
[0007] Optionally, a return spring is arranged between the first scissor arm and the second scissor arm.
[0008] Optionally, two groups of the first scissor arms and the second scissor arms are respectively arranged on the first side and the second side of the first eye support and the second eye support, and the cylinder is located between the two groups of the first scissor arms and the second scissor arms.
[0009] Optionally, the outer edges of the first eye tray and the second eye tray are arc-shaped.
[0010] Optionally, the first eye tray and the second eye tray are made of silicone material.
[0011] Optionally, a fill light is provided on the lens mount, and the fill light is located on the end surface of the lens mount facing the inside of the barrel.
[0012] Optionally, a plurality of fill lights are arranged at intervals around the lens.
[0013] Optionally, the fill light is a cobalt blue lamp.
[0014] Optionally, a shutter button for controlling the lens and a switch button for controlling the fill light are provided on the side of the lens mount.
[0015] The utility model has the following advantages:
[0016] The utility model provides a detection device for tear film breakup time, comprising: an eye expander, an atomizing structure and a collection device. The eye expander comprises a barrel and an eye expander support, the opening at the bottom of the barrel is located on the eye expander support, and the eye expander support is suitable for separating the upper and lower eyelids of animals. The atomizing structure comprises a container and an atomizing rod, the first end of the atomizing rod is connected to the container, the second end is suitable for extending into the barrel to near the bottom of the barrel, and the second end of the atomizing rod is provided with an atomizing nozzle. The collection device comprises a lens seat and a lens, the size of the lens seat is larger than the radial size of the barrel, and is suitable for overlapping the top of the barrel, and the lens is located at a position where the lens seat faces the inside of the barrel.
[0017] When in use, the eye expander's eye expander holder can be placed at the corresponding position of the animal's upper and lower eyelids, and the animal's upper and lower eyelids can be separated, and then the atomizing rod can be extended into the barrel until the atomizing nozzle is close to the bottom of the barrel. The sodium fluorescein solution in the container can be evenly sprayed on the animal's eye surface through the atomizing nozzle by squeezing or pressing. The atomizing structure is removed, and the lens holder of the collection device is overlapped on the upper opening of the barrel. The lens can be directed toward the animal's eye surface, so that the animal's eye surface can be photographed and collected, so as to facilitate the subsequent calculation of the test results. In the above drug administration process, an atomizing nozzle is used, which greatly reduces the stimulation of the drug solution on the animal's eye surface, avoids the animal's struggle due to stimulation, and reduces the interference of the animal's struggle on the experimental results. Then, there is no need to anesthetize the animal, and the animal can be tested for other indicators. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] In order to more clearly illustrate the specific implementation methods of the utility model or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.
[0019] Figure 1 A schematic structural diagram of a tear film breakup time detection device provided in this embodiment is shown;
[0020] Figure 2 The schematic diagram of the structure of the spray structure in this embodiment is shown;
[0021] Figure 3 The schematic diagram of the structure of the acquisition device in this embodiment is shown;
[0022] Figure 4 A schematic diagram of the structure of the first eye rest in this embodiment is shown;
[0023] Figure 5 A schematic diagram of the structure of the acquisition device in this embodiment is shown from a bottom view;
[0024] Figure 6 A side view schematic diagram of the structure of the acquisition device in this embodiment is shown.
[0025] Description of reference numerals:
[0026] 11. Cylinder body; 21. Container; 22. Atomizing rod; 23. Atomizing nozzle; 31. Lens mount; 32. Lens; 33. Fill light; 34. Shutter button; 35. Switch button; 41. First scissor arm; 411. Articulated axis; 42. Second scissor arm; 43. First eye support; 44. Second eye support; 45. Return spring. DETAILED DESCRIPTION
[0027] The technical solution of the utility model will be described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0028] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.
[0029] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0030] In addition, the technical features involved in the different embodiments of the present invention described below can be combined with each other as long as they do not conflict with each other.
[0031] like Figure 1 , Figure 2 and Figure 3 As shown, in this embodiment, the utility model provides a tear film breakup time detection device, including: an eye expander, an atomization structure and a collection device.
[0032] The eye expander comprises a barrel 11 and an eye expander support. The opening at the bottom of the barrel 1 is located on the eye expander support. The eye expander support is suitable for separating the upper and lower eyelids of an animal.
[0033] The atomization structure includes a container 21 and an atomization rod 22. The first end of the atomization rod 22 is connected to the container, and the second end is suitable for extending into the barrel 11 to near the bottom of the barrel 11. The second end of the atomization rod 22 is provided with an atomization nozzle 23. The cross section of the barrel 11 can be circular, which can be more convenient to adapt to the shape of the eye surface, convenient for spraying drugs and collecting images. The barrel 11 is hollow and transparent from top to bottom, with a top opening and a bottom opening. The top opening is conducive to the atomization rod 22 to extend into and prevent the collection device, and the bottom opening can face the eye surface of the animal.
[0034] The acquisition device includes a lens holder 31 and a lens 32. The size of the lens holder 31 is larger than the radial size of the barrel 11 and is suitable for overlapping the top of the barrel 11. The lens 32 is located at the position where the lens holder 31 faces the inside of the barrel 11. The cross section of the lens holder 31 can be circular and larger than the radial size of the barrel 11. A boss can be provided at the bottom of the lens holder 31, and the lens is located on the boss, so that the lens 32 can be further extended into the barrel 11 to avoid being blocked.
[0035] When in use, the eye expander can be placed at the corresponding position of the upper eyelid and the lower eyelid of the animal. The eye expander can separate the upper and lower eyelids of the animal. Then, the atomizing rod 22 is extended into the barrel 11 until the atomizing nozzle 23 is close to the bottom of the barrel 11 to ensure that the spray range of the atomizing nozzle 23 can cover the opening at the bottom of the barrel 11. Then, the sodium fluorescein solution in the container 21 can be evenly sprayed on the animal's eye surface through the atomizing nozzle 23 by squeezing or pressing. The atomizing structure is removed, and the lens holder 31 of the collection device is overlapped on the upper opening of the barrel 11. The lens 32 can be directed to the animal's eye surface, so as to take pictures of the animal's eye surface for collection, so as to facilitate the subsequent calculation of the test results. The atomizing nozzle 23 is used in the above drug administration process, which greatly reduces the stimulation of the drug solution on the animal's eye surface, avoids the animal from struggling due to stimulation, and reduces the interference of the animal's struggle on the experimental results. Then, there is no need to anesthetize the animal, and the animal can be tested for other indicators.
[0036] like Figure 1As shown, the eye expansion support seat includes a first scissor arm 41 and a second scissor arm 42 hinged together, and a first eye support 43 and a second eye support 44 respectively located at the bottom of the first scissor arm 41 and the second scissor arm 42. The first scissor arm 41 and the second scissor arm 42 can be connected by a hinge shaft 411. When the tops of the first scissor arm 41 and the second scissor arm 42 move in a direction close to each other, the first eye support 43 and the second eye support 44 can move in a direction away from each other. The first eye support 43 and the second eye support 44 are in contact with the upper eyelid and the lower eyelid of the animal respectively, thereby driving the upper eyelid and the lower eyelid of the animal to separate, and the operation is simple. When the tops of the first scissor arm 41 and the second scissor arm 42 move in a direction away from each other, the first eye support 43 and the second eye support 44 move in a direction close to each other, and the expansion state of the upper and lower eyelids of the animal is released.
[0037] like Figure 1 As shown, in this embodiment, a return spring 45 is provided between the first scissor arm 41 and the second scissor arm 42. The return spring 45 can be provided above the hinge of the first scissor arm 41 and the second scissor arm 42, and is respectively connected to the first scissor arm 41 and the second scissor arm 42. When it is necessary to release the expansion state of the upper and lower eyelids of the animal, the force on the first scissor arm 41 and the second scissor arm 42 can be cancelled, and the return spring 45 drives the first scissor arm 41 and the second scissor arm 42 to move away from each other through elastic force.
[0038] In this embodiment, two sets of first scissor arms 41 and second scissor arms 42 are respectively arranged on the first side and second side of the first eye support 43 and second eye support 44, and the cylinder 11 is located between the two sets of first scissor arms 41 and second scissor arms 42. The two sets of first scissor arms 41 and second scissor arms 42 have the same structure and shape, and such an arrangement is conducive to limiting the cylinder 11 and preventing the cylinder 11 from shaking.
[0039] like Figure 4 As shown, in this embodiment, the outer edges of the first eye tray 43 and the second eye tray 44 are arc-shaped, so that the first eye tray 43 and the second eye tray 44 can better fit the shape of the animal's eyelids, so as to facilitate the expansion of the upper and lower eyelids of the animal.
[0040] In this embodiment, the first eye rest 43 and the second eye rest 44 are made of silicone material, thereby preventing the first eye rest 43 and the second eye rest 44 from irritating the eyelids of the animal, so that the first eye rest 43 and the second eye rest 44 can more gently expand the upper and lower eyelids of the animal, reducing the chance of the animal struggling.
[0041] like Figure 3 and Figure 5As shown, in this embodiment, a fill light 33 is provided on the lens mount 31, and the fill light 33 is located on the end surface of the lens mount 31 facing the barrel 11. Following the above example, the fill light 33 can be arranged around the boss, so that the animal's eye surface can be illuminated by the fill light 33.
[0042] like Figure 3 and Figure 5 As shown, in this embodiment, a plurality of fill lights 33 are arranged at intervals around the lens 32. For example, four fill lights 33 can be arranged on the lens holder 31, and the intervals between the fill lights 33 surround the four sides of the lens 32, thereby providing uniform illumination to the animal's eyeballs.
[0043] In this embodiment, the fill light 33 is a cobalt blue light.
[0044] like Figure 5 and Figure 6 As shown, in this embodiment, a shutter button 34 for controlling the lens 32 and a switch button 35 for controlling the fill light 33 are provided on the side of the lens mount 31 .
[0045] Obviously, the above embodiments are merely examples for the purpose of clear explanation, and are not intended to limit the implementation methods. For those skilled in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation methods here. The obvious changes or modifications derived therefrom are still within the scope of protection of the invention.
Claims
1. A tear film breakup time detection device, characterized in that: include: An eye expander comprises a barrel (11) and an eye expander support, wherein the opening at the bottom of the barrel (11) is located on the eye expander support, and the eye expander support is suitable for separating the upper and lower eyelids of an animal; An atomizing structure, comprising a container (21) and an atomizing rod (22), wherein a first end of the atomizing rod (22) is in communication with the container (21), and a second end is adapted to extend into the cylinder (11) to a position close to the bottom of the cylinder (11), and an atomizing nozzle (23) is disposed at the second end of the atomizing rod (22); The collecting device comprises a lens (32) seat (31) and a lens (32); the size of the lens (32) seat (31) is larger than the radial size of the barrel (11) and is suitable for overlapping the top of the barrel (11); the lens (32) is located at a position where the lens (32) seat (31) faces the inside of the barrel (11).
2. The detection device according to claim 1, characterized in that: The eye expansion bracket comprises a first scissor arm (41) and a second scissor arm (42) which are hinged together, and a first eye support (43) and a second eye support (44) respectively located at the bottom of the first scissor arm (41) and the second scissor arm (42).
3. The detection device according to claim 2, characterized in that: A return spring (45) is provided between the first scissor arm (41) and the second scissor arm (42).
4. The detection device according to claim 3, characterized in that: The two groups of the first scissor arms (41) and the second scissor arms (42) are respectively arranged on the first side and the second side of the first eye support (43) and the second eye support (44), and the cylinder (11) is located between the two groups of the first scissor arms (41) and the second scissor arms (42).
5. The detection device according to claim 2, characterized in that: The outer edges of the first eye tray (43) and the second eye tray (44) are arc-shaped.
6. The detection device according to claim 5, characterized in that: The first eye tray (43) and the second eye tray (44) are made of silicone material.
7. The detection device according to claim 1, characterized in that: A fill light (33) is provided on the lens (32) seat (31), and the fill light (33) is located on the end surface of the lens (32) seat (31) facing the inside of the barrel (11).
8. The detection device according to claim 7, characterized in that: A plurality of fill lights (33) are arranged at intervals around the lens (32).
9. The detection device according to claim 7, characterized in that: The fill light (33) is a cobalt blue lamp.
10. The detection device according to claim 7, characterized in that: A shutter button (34) for controlling the lens (32) and a switch button (35) for controlling the fill light (33) are arranged on the side of the lens (32) seat (31).