PRP preparation device

Abstract

The utility model discloses a PRP preparation device which comprises an outer centrifugal tube internally provided with a first containing cavity, an inner centrifugal tube internally provided with a second containing cavity and an upper cover used for sealing the other end of the outer centrifugal tube, and one end of the inner centrifugal tube is connected with one end of the outer centrifugal tube in a sliding and inserted mode. The inner centrifugal tube is arranged on the upper cover, the first sealing cover is used for sealing one end of the inner centrifugal tube, the second sealing cover is arranged on the upper cover, and the first sealing cover and the second sealing cover can be punctured by a needle head. According to the device, the problem that red blood cells are easily sucked into centrifugate of secondary centrifugation in the PRP preparation process can be solved, the PRP preparation effect is improved, and meanwhile, the risk of external pollution in the PRP preparation process is greatly reduced.

Description

Technical Field

[0001] The utility model belongs to the technical field of medical equipment, and specifically relates to a PRP preparation device. Background Art

[0002] Platelet-rich plasma (PRP for short) is an extract separated from autologous blood, containing high concentrations of platelets and growth factors. There are two types of PRP classified by the concentration of white blood cells in it: platelet-rich plasma containing high concentrations of white blood cells, referred to as L-PRP (Leukocyte Platelet-Rich Plasma, containing a small amount of red blood cells), is mainly used for clinical treatments such as bone repair and difficult-to-heal wounds; platelet-rich plasma containing no or low concentrations of white blood cells is referred to as P-PRP (Pure Platelet-Rich Plasma, without red blood cells), which is more suitable for sports injuries and cosmetic surgery applications.

[0003] Most of the existing PRP preparations are prepared by the secondary centrifugation method. The process of preparing PRP by the secondary centrifugation method is: open the centrifuge tube to inject blood, open the centrifuge tube again after the first centrifugation to extract the red blood cells, open the centrifuge tube again after the second centrifugation to extract the serum, and then extract the remaining PRP and inject it into the human body. Two extended needles and syringes are also used. This preparation method has the following problems when preparing PRP: 1. Other equipment is used for extraction multiple times during the preparation process, which may cause PRP to be contaminated; 2. When using a syringe to extract red blood cells, because the needle of the syringe is small and the suction surface of the syringe needle is an inclined surface, when the extraction is close to the separation interface, it is easy for the needle to deflect and then suck in the red blood cells, thereby affecting the final preparation effect of PRP, and the syringe extraction efficiency is low. Utility Model Content

[0004] The purpose of the utility model is to provide a PRP preparation device, which can solve the problem that red blood cells are easily sucked into the centrifuge liquid of the second centrifugation during the PRP preparation process, improve the preparation effect of PRP, and greatly reduce the risk of external contamination during the PRP preparation process.

[0005] The utility model adopts a technical solution to solve its technical problem, which is to propose a PRP preparation device, including an outer centrifuge tube with a first accommodating cavity, an inner centrifuge tube with a second accommodating cavity, one end of the inner centrifuge tube is slidably plugged with one end of the outer centrifuge tube, and also includes an upper cover for sealing the other end of the outer centrifuge tube, a first sealing cover for sealing one end of the inner centrifuge tube, and a second sealing cover arranged on the upper cover, and the first sealing cover and the second sealing cover can be pierced by a needle.

[0006] In an embodiment of the present application, a sealing ring is provided at one end of the inner centrifuge tube that is inserted into the outer centrifuge tube, and the sealing ring abuts against the inner wall of the outer centrifuge tube and the outer wall of the inner centrifuge tube.

[0007] In an embodiment of the present application, a guide ring is provided at one end of the outer centrifuge tube, the sealing ring is embedded between the guide ring and the inner centrifuge tube, and the end of the sealing ring is in contact with the guide ring.

[0008] In an embodiment of the present application, a reinforcement edge is provided on the surface of the sealing ring, and the reinforcement edge abuts against the inner centrifugal tube.

[0009] In the embodiment of the present application, a clamping edge is provided on the upper cover, and the other end of the inner centrifuge tube abuts against the clamping edge.

[0010] In the embodiment of the present application, the upper cover is further provided with ventilation holes connecting the first accommodating cavity and the second accommodating cavity with the outside air, and the ventilation holes are sealed with a waterproof, breathable and anti-bacterial film.

[0011] In the embodiment of the present application, the outer centrifuge tube and the inner centrifuge tube are both conical tubes, the first sealing cover seals the flat end of the inner centrifuge tube, and the flat end of the inner centrifuge tube is plugged into the flat end of the outer centrifuge tube.

[0012] In the embodiment of the present application, the second sealing cover is fixed to the edge of the upper cover.

[0013] In the embodiment of the present application, the first sealing cover and the second sealing cover both include a rubber plug that can be pierced by a needle, and an aluminum cover for fixing the rubber plug on one end of the inner centrifuge tube or the upper cover.

[0014] In the embodiment of the present application, the outer centrifuge tube and the inner centrifuge tube are both made of transparent material.

[0015] The beneficial effects of the utility model are:

[0016] 1. The PRP preparation device proposed by the utility model extracts the upper supernatant after the first centrifugation in the outer centrifuge tube into the inner centrifuge tube by pulling the inner centrifuge tube, and performs the second centrifugation, so that the red blood cells after the first separation will not be diverted to the second containing chamber, thereby improving the preparation effect of PRP, and expanding the separation contact area when the separation supernatant and the red blood cells are separated, thereby improving the extraction efficiency of the supernatant after the first separation;

[0017] 2. The PRP preparation device proposed by the utility model uses a syringe to pierce the sealing cap of the inner centrifuge tube and the upper cover to inject liquid into the outer centrifuge tube or extract liquid from the inner centrifuge tube. During this process, the outer centrifuge tube and the inner centrifuge tube are both in a sealed state, thereby preventing the blood in the outer centrifuge tube and the inner centrifuge tube from contacting with the outside air, greatly reducing the risk of the PRP preparation process being contaminated by the outside;

[0018] 3. The utility model proposes a PRP preparation device, in which a guide ring is provided at one end of the outer centrifuge tube, and a sealing ring is embedded between the guide ring and the inner centrifuge tube. When the operator pulls or pushes the inner centrifuge tube, the sealing ring is stuck in the guide ring and then abuts against the outer surface of the inner centrifuge tube, so that the inner centrifuge tube will not shake during the movement, thereby improving the stability after the first centrifugation and when extracting the supernatant. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The accompanying drawings, which are incorporated into the specification and constitute a part of the specification, illustrate embodiments of the utility model and are used together with the description to explain the principles of the utility model. In these drawings, similar reference numerals are used to represent similar elements. The drawings described below are some embodiments of the utility model, rather than all embodiments. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without paying creative work.

[0020] Figure 1 An exploded view of a PRP preparation device according to an embodiment of the utility model;

[0021] Figure 2 A cross-sectional view of a PRP preparation device according to an embodiment of the utility model;

[0022] Figure 3 This is a liquid level distribution diagram after the first centrifugation of a PRP preparation device according to an embodiment of the utility model;

[0023] Figure 4 This is a liquid level distribution diagram after the second centrifugation of a PRP preparation device according to an embodiment of the utility model;

[0024] Figure 5 A schematic diagram of a sealing ring of a PRP preparation device according to an embodiment of the utility model;

[0025] Figure 6 This is a schematic diagram of an upper cover of a PRP preparation device according to an embodiment of the utility model.

[0026] In the figure: 1, outer centrifuge tube; 2, inner centrifuge tube; 3, upper cover; 31, air vent; 4, first sealing cover; 41, rubber plug; 42, aluminum cover; 5, second sealing cover; 6, sealing ring; 7, guide ring; 8, reinforcement edge; 9, clamping edge; 10, first centrifuge target liquid; 11, second centrifuge target liquid. DETAILED DESCRIPTION

[0027] In order to more clearly illustrate the embodiments of the utility model and the technical solutions in the prior art, the specific implementation methods of the utility model will be described below with reference to the accompanying drawings. Obviously, the accompanying drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings and other implementation methods can be obtained based on these drawings without creative work. In addition, the design orientation only represents the relative position relationship between the components, not the absolute position relationship.

[0028] The present invention provides a PRP preparation device. Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 , mainly includes an outer centrifuge tube 1, an inner centrifuge tube 2, an upper cover 3, a first sealing cover 4, and a second sealing cover 5.

[0029] A PRP preparation device according to an embodiment of the utility model comprises an outer centrifuge tube 1 provided with a first accommodating cavity, an inner centrifuge tube 2 provided with a second accommodating cavity, one end of the inner centrifuge tube 2 being slidably plugged with one end of the outer centrifuge tube 1, and further comprises an upper cover 3 for sealing the other end of the outer centrifuge tube 1, a first sealing cover 4 for sealing one end of the inner centrifuge tube 2, and a second sealing cover 5 arranged on the upper cover 3, wherein both the first sealing cover 4 and the second sealing cover 5 can be pierced by a needle.

[0030] In the present application, when preparing PRP by the device, the collected patient blood is first pierced through the second sealing cover 5 by a syringe and transported to the cavity between the outer centrifuge tube 1 and the inner centrifuge tube 2, and then the entire device is installed in a centrifuge, and the centrifuge is started to centrifuge the target liquid after setting the centrifugal time and centrifugal force. After the first centrifugation, the blood is separated into the upper supernatant and the lower red blood cells, wherein the upper supernatant is the original liquid during the second centrifugation. Pull the inner centrifuge tube 2 downward so that the liquid level of the upper supernatant is higher than the edge of the inner centrifuge tube 2, and at this time, the upper supernatant will flow into the second accommodating cavity of the inner centrifuge tube 2.

[0031] Compared with the existing preparation process, after the first centrifugation, the centrifuge tube is opened to extract the red blood cells. When the red blood cells are extracted with a syringe, due to the small needle of the syringe, when the extraction is close to the separation interface, it is easy for the needle to deflect and then suck in the red blood cells, thereby affecting the final PRP preparation effect, and the syringe extraction efficiency is low. In the present application, by pulling the inner centrifuge tube 2 downward, the supernatant on the upper layer flows into the second accommodating chamber of the inner centrifuge tube 2, and the entire relative displacement process between the inner centrifuge tube 2 and the outer centrifuge tube 1 is stable, so that the red blood cells after the first separation will not be diverted to the second accommodating chamber, thereby improving the preparation effect of PRP, and expanding the separation contact area when the separation supernatant and red blood cells are separated, and improving the extraction efficiency of the supernatant after the first separation.

[0032] After the supernatant flows into the second accommodating chamber after the first separation, the inner centrifuge tube 2 is pushed upward so that the inner centrifuge tube 2 abuts against the upper cover 3, and the centrifuge is started after resetting the centrifugal time and centrifugal force. After the second centrifugation, the liquid in the inner centrifuge tube 2 is separated into an upper layer of liquid and a lower layer of PRP. Finally, the first sealing cover 4 is pierced with a syringe to extract the lower layer of PRP.

[0033] Compared with the existing preparation method, the centrifuge tube is opened and blood is injected. After the first centrifugation, the centrifuge tube is opened again to extract the red blood cells with a syringe. After the second centrifugation, the centrifuge tube is opened again to extract the serum with a syringe, and the remaining PRP is extracted with a syringe. The centrifuge tubes are all exposed to the external environment, which greatly increases the risk of the PRP preparation process being contaminated by the outside world. In the present application, the blood is injected into the preparation device by piercing the second sealing cover 5 with a syringe, and finally the PRP is extracted from the first sealing cover 4. The entire preparation process is in a sealed state, thereby avoiding the contact between the blood in the preparation device and the outside air, greatly reducing the probability of PRP being contaminated by environmental factors.

[0034] In the present application, a sealing ring 6 is arranged on one side of the inner centrifuge tube 2 inserted into the outer centrifuge tube 1. The sealing ring 6 is made of a flexible material. The sealing ring 6 abuts against the inner wall of the outer centrifuge tube 1 and the outer wall of the inner centrifuge tube 2, thereby increasing the sealing effect between the inner centrifuge tube 2 and the outer centrifuge tube 1.

[0035] Furthermore, a guide ring 7 is provided at one end of the outer centrifuge tube 1, and a sealing ring 6 is embedded between the guide ring 7 and the inner centrifuge tube 2, and the end of the sealing ring 6 abuts against the end of the guide ring 7. When the operator pulls or pushes the inner centrifuge tube 2, the sealing ring 6 is stuck in the guide ring 7 and then abuts against the outer surface of the inner centrifuge tube 2, so that the inner centrifuge tube 2 will not shake during the movement, thereby improving the stability after the first centrifugation and when extracting the supernatant.

[0036] Preferably, a reinforcing edge 8 integrally connected to the sealing ring 6 is provided on the surface of the sealing ring 6, and the reinforcing edge 8 abuts against the inner centrifuge tube 2, thereby increasing the resistance of the inner centrifuge tube 2 when moving. The inner centrifuge tube 2 moves relatively slowly when adjusting its position, thereby being able to accurately control the movement of the inner centrifuge tube 2, ensuring that the red blood cells after the first separation will not be diverted into the second containing chamber, thereby improving the preparation effect of PRP.

[0037] In the present application, a clamping edge 9 is provided on the upper cover 3. After obtaining the supernatant after the first centrifugation, the inner centrifuge tube 2 is pushed so that the other end of the inner centrifuge tube 2 abuts against the upper cover 3. After the inner centrifuge tube 2 abuts against the upper cover 3, the clamping edge 9 abuts against the outer surface of the inner centrifuge tube 2. As can be seen from the above, the red blood cells after the first centrifugation are still present in the first accommodating cavity of the outer centrifuge tube 1. Therefore, in order to avoid the red blood cells after the first centrifugation from being accidentally thrown into the inner centrifuge tube 2 due to the loose abutment between the inner centrifuge tube 2 and the upper cover 3 during the second centrifugation, the clamping edge 9 is provided to block the red blood cells splashing during the second centrifugation.

[0038] Furthermore, the upper cover 3 is provided with a vent hole 31 that connects the first accommodating chamber and the second accommodating chamber with the outside air. The vent hole 31 is sealed with a waterproof and breathable anti-bacterial film so that the outside air can enter the first accommodating chamber and the second accommodating chamber through the vent hole 31. The reason why the vent hole 31 is provided to connect the first accommodating chamber and the second accommodating chamber with the outside environment is that in the present application, the supernatant after the first separation is extracted by pulling the inner centrifuge tube 2. If the inner part of the outer centrifuge tube 1 is in a completely sealed state, when the inner centrifuge tube 2 is pulled, the pressure difference between the inside and the outside will continue to increase, making it difficult for the inner centrifuge tube 2 to reach the stratification position of the first centrifuged blood, and the supernatant after the first separation cannot be completely extracted, thereby affecting the preparation effect of PRP.

[0039] In the present application, both the outer centrifuge tube 1 and the inner centrifuge tube 2 are conical tubes, the first sealing cover 4 seals the flat end of the inner centrifuge tube 2, and the flat end of the inner centrifuge tube 2 is plugged into the flat end of the outer centrifuge tube 1. The inner centrifuge tube 2 and the outer centrifuge tube 1 are both set as conical tubes because the conical tube has the best centrifugal effect in the centrifuge, thereby making the preparation effect of PRP better. And the first sealing cover 4 and the second sealing cover 5 are arranged on different sides, thereby improving the recognition of the first sealing cover 4 and the second sealing cover 5, and the operator can quickly and accurately complete the preparation of PRP.

[0040] In the present application, the second sealing cover 5 is arranged at the edge of the upper cover 3 , so as to facilitate the collected patient blood to be transported to the cavity between the outer centrifuge tube 1 and the inner centrifuge tube 2 by piercing the second sealing cover 5 with a syringe.

[0041] In the present application, the first sealing cover 4 and the second sealing cover 5 both include a rubber plug 41 that can be pierced by a needle, and an aluminum cover 42 that fixes the rubber plug 41 to one end of the inner centrifugal tube 2 or the upper cover 3, and the aluminum cover 42 exposes the middle part of the rubber plug 41. The first sealing cover 4 and the second sealing cover 5 both include a rubber plug 41 and an aluminum cover 42, and the aluminum cover 42 is wrapped around the outside of the rubber plug 41, so that when the aluminum cover 42 is fixed to the inner centrifugal tube 2 and the upper cover 3, the rubber plug 41 is also fixed to the inner centrifugal tube 2 and the upper cover 3 at the same time. However, the aluminum cover 42 does not completely wrap the rubber plug 41, but exposes the middle part of the rubber plug 41, so that the needle of the syringe can penetrate the exposed part of the rubber plug 41 and extend into the first accommodating cavity and the second accommodating cavity. Compared with the conventional sealing method of gluing an aluminum foil sealing sheet to the opening to be sealed and fixing the rubber plug 41 to the inner centrifuge tube 2 and the upper cover 3 through the aluminum cover 42, the fixing and sealing effects are better, thereby preventing the blood in the inner centrifuge tube 2 and the upper cover 3 from leaking out and reducing the risk of medical accidents.

[0042] In order to more clearly distinguish the boundary lines of each layer obtained by each separation operation, the outer centrifuge tube 1 and the inner centrifuge tube 2 are both made of transparent material.

[0043] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device comprising a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the statement "comprise a ..." do not exclude the presence of other identical elements in the process, method, article or device comprising the elements.

[0044] The above contents are further detailed descriptions of the present invention in combination with specific preferred implementation methods, and the specific embodiments of the present invention cannot be considered to be limited to these descriptions. For ordinary technicians in the technical field to which the present invention belongs, several simple deductions or substitutions can be made without departing from the concept of the present invention, which should be regarded as falling within the protection scope of the present invention.

Claims

1. A PRP preparation device, characterized in that: The invention comprises an outer centrifuge tube (1) provided with a first accommodating cavity, an inner centrifuge tube (2) provided with a second accommodating cavity, one end of the inner centrifuge tube (2) being slidably plugged into one end of the outer centrifuge tube (1), and further comprises an upper cover (3) for sealing the other end of the outer centrifuge tube (1), a first sealing cover (4) for sealing one end of the inner centrifuge tube (2), and a second sealing cover (5) provided on the upper cover (3), wherein both the first sealing cover (4) and the second sealing cover (5) can be pierced by a needle.

2. A PRP preparation device according to claim 1, characterized in that: One end of the inner centrifuge tube (2) inserted into the outer centrifuge tube (1) is provided with a sealing ring (6), and the sealing ring (6) abuts against the inner wall of the outer centrifuge tube (1) and the outer wall of the inner centrifuge tube (2).

3. A PRP preparation device according to claim 2, characterized in that: A guide ring (7) is provided at one end of the outer centrifuge tube (1), the sealing ring (6) is embedded between the guide ring (7) and the inner centrifuge tube (2), and the end of the sealing ring (6) is in contact with the guide ring (7).

4. A PRP preparation device according to claim 3, characterized in that: A reinforcing edge (8) is provided on the surface of the sealing ring (6), and the reinforcing edge (8) abuts against the inner centrifuge tube (2).

5. A PRP preparation device according to claim 1, characterized in that: The upper cover (3) is provided with a clamping edge (9), and the other end of the inner centrifuge tube (2) abuts against the clamping edge (9).

6. A PRP preparation device according to claim 5, characterized in that: The upper cover (3) is also provided with an air vent (31) for connecting the first accommodating cavity and the second accommodating cavity with the outside air, and the air vent (31) is sealed with a waterproof, breathable, antibacterial film.

7. A PRP preparation device according to claim 1, characterized in that: The outer centrifuge tube (1) and the inner centrifuge tube (2) are both conical tubes; the first sealing cover (4) seals the flat end of the inner centrifuge tube (2); and the flat end of the inner centrifuge tube (2) is plugged into the flat end of the outer centrifuge tube (1).

8. A PRP preparation device according to claim 1, characterized in that: The second sealing cover (5) is fixed to the edge of the upper cover (3).

9. A PRP preparation device according to claim 8, characterized in that: The first sealing cover (4) and the second sealing cover (5) both comprise a rubber plug (41) that can be pierced by a needle, and an aluminum cover (42) for fixing the rubber plug (41) to one end of the inner centrifuge tube (2) or to the upper cover (3).

10. A PRP preparation device according to claim 1, characterized in that: The outer centrifuge tube (1) and the inner centrifuge tube (2) are both made of transparent material.

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