Filtering structure for furosemide oral solution production

By designing a filtering structure that includes mixing barrels and diversion components in the production of Symami mouth, it solves the problem of too fast filtration speed, realizes the uniform and fully filtration of the drug, and improves the quality of the medicinal effect.

CN222400978UActive Publication Date: 2025-01-28南京联智医药科技有限公司
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Patent Information

Application Number
CN202323437383.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2023-12-18
Publication Date
2025-01-28
Estimated Expiration
2033-12-18

AI Technical Summary

Technical Problem

In the production of furosemide oral solution, the existing filter structure adopts direct dumping method to cause the filtration speed to be too fast, which may prevent the drug from fully passing the filter or interact unnecessary with the filter media, resulting in some drugs being trapped in the filtration If the drug cannot be collected in the instrument, it will affect the efficacy and quality of the drug.

Method used

Design a filtering structure that includes a mixing barrel, a mixing mechanism and a diversion component. The mixing barrel is provided with a mixing mechanism to enhance the solubility. The diversion components include the expansion tube, the catheter, the horizontal long tube and the diversion tube. Through these structures, the fascin -oral solution is evenly flowing the filter film evenly to slow down the filtration speed.

Benefits of technology

Through this design, the filtration speed of the segemodic oral solution is controlled. The drug can be uniform and fully through the filter to reduce the unnecessary interaction between the drug and the filter medium, thereby improving the quality of the drug.

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Abstract

The utility model relates to the field of medicine solution production and filtration, and discloses a filtering structure for furosemide oral solution production, which solves the problem that a furosemide oral solution is inconvenient to filter due to too high flow speed when being filtered, and comprises a stirring barrel, a stirring mechanism is arranged in the stirring barrel, and the stirring mechanism is arranged in the stirring barrel. A filter box is fixedly connected to the bottom of the stirring barrel; a shunting assembly is arranged in the filter box; the flow dividing assembly comprises a flared pipe fixedly connected to the inner wall of the filter box, a guide pipe is fixedly connected to the bottom of the flared pipe, a horizontal long pipe is fixedly connected to the bottom of the guide pipe, three groups of flow dividing pipes are fixedly connected to the two sides of the horizontal long pipe respectively, and four groups of branch pipes with openings gradually increased in size are fixedly connected to the bottoms of the flow dividing pipes respectively; and through the cooperation of the branch pipes and the shunt pipes, the purpose of reducing the flow velocity of the liquid during filtration is finally achieved.
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Description

Technical Field

[0001] The utility model relates to the technical field of drug solution production filtration, in particular to a filtration structure for the production of furosemide oral solution. Background Art

[0002] Furosemide oral solution is an oral drug whose main ingredient is furosemide. Furosemide is a type of diuretic and is commonly used to treat hypertension, edema and other diseases. When producing furosemide oral solution, it is necessary to mix furosemide and other drugs with the required auxiliary materials in a certain proportion, add a certain amount of water to dissolve them, and then filter the liquid formed after the drug and auxiliary materials are mixed to remove impurities and microorganisms. Subsequently, the filtered solution is sterilized by high temperature and high pressure or ultraviolet radiation to ensure the sterility of the product. Finally, quality inspection is carried out for final packaging. However, the existing filtration structure for the production of furosemide oral solution adopts a direct pouring method to add the furosemide oral solution into the filtration mechanism. This method will result in too fast a filtration speed, and too fast a filtration speed may prevent the drug from fully passing through the filter or interacting with the filter medium unnecessarily, resulting in part of the drug being retained in the filter and unable to be collected, affecting the quality of the drug.

[0003] In view of the above problems, a filtering structure for producing furosemide oral solution is proposed. Utility Model Content

[0004] The utility model aims to provide a filtering structure for producing furosemide oral solution. The device is used to work, thereby solving the problem of too fast filtering speed during the production of furosemide oral solution.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a filtering structure for producing furosemide oral solution, comprising a stirring barrel, a stirring mechanism is arranged inside the stirring barrel, a filtering box is fixedly connected to the bottom of the stirring barrel, and a flow dividing component is arranged inside the filtering box;

[0006] The diversion component includes a flared tube fixedly connected to the inner wall of the filter box, a conduit fixedly connected to the bottom of the flared tube, a horizontal long tube fixedly connected to the bottom of the conduit, three groups of diversion tubes fixedly connected to the two sides of the horizontal long tube, respectively, the bottom of the diversion tube is fixedly connected to the first branch tube, the second branch tube, the third branch tube and the fourth branch tube with openings of increasing sizes, the first branch tube, the second branch tube and the third branch tube are fixedly connected to the inner walls with blocking protrusions for slowing down the flow of water, and the diversion tubes are symmetrically arranged in pairs and arranged in sequence on both sides of the horizontal long tube.

[0007] Preferably, a filter membrane for filtering is fixedly connected to the inner wall of the filter box, and a connection port is opened on the upper surface of the filter box.

[0008] Preferably, the stirring mechanism includes a motor fixedly connected to the upper surface of the stirring barrel, the output end of the motor is fixedly connected to a rotating shaft, the outer surface of the rotating shaft is fixedly connected to a scraper rod, the inner wall of the stirring barrel is fixedly connected to a limiting wall, the scraper rod is fitted with the limiting wall, the outer surface of the rotating shaft is also fixedly connected to a stirring rod, the inner wall of the limiting wall is fixedly connected to a valve, and the opening direction of the valve corresponds to the connecting port.

[0009] Preferably, the surface of the stirring rod is provided with holes for enhancing turbulence.

[0010] Preferably, a material inlet channel is fixedly connected to the outside of the mixing barrel, and a material outlet channel is fixedly connected to the bottom of the filter box.

[0011] Preferably, an inclined bottom surface is provided inside the filter box, and the inclination direction of the inclined bottom surface corresponds to the opening direction of the discharge channel.

[0012] Preferably, a bracket for maintaining the stability of the equipment is fixedly connected to the bottom of the filter box.

[0013] Compared with the prior art, the beneficial effects of the utility model are as follows:

[0014] The utility model provides a filtering structure for the production of furosemide oral solution. The dissolved furosemide oral solution first enters a flared tube, then flows from the flared tube into a horizontal long tube through a catheter, and then flows from the horizontal long tube to each branch tube. Branch tubes with different opening sizes are arranged at the bottom of each branch tube. The distance between each branch tube is different. As the opening size continues to increase, the distance between the two branch tubes continues to decrease, so that the furosemide oral solution flows out from each branch tube and passes through the filter membrane evenly and slowly, thereby finally achieving the purpose of slowing down the filtration speed. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0016] Figure 2 This is a schematic diagram of the plane structure of the filter box of the utility model;

[0017] Figure 3 This is a schematic diagram of the structure of the flow diversion component of the utility model;

[0018] Figure 4 This is a schematic diagram of the stirring mechanism structure of the utility model.

[0019] In the figure: 1. stirring barrel; 2. stirring mechanism; 21. motor; 22. rotating shaft; 23. limiting wall; 24. stirring rod; 25. hole; 26. scraper rod; 27. valve; 3. feeding channel; 4. filter box; 41. connecting port; 42. filter membrane; 43. inclined bottom surface; 5. bracket; 6. diverter assembly; 61. flaring pipe; 62. conduit; 63. diverter pipe; 64. first branch pipe; 65. second branch pipe; 66. third branch pipe; 67. fourth branch pipe; 68. flow blocking bump; 69. horizontal long pipe; 7. discharge channel. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0021] In order to further understand the content of the utility model, the utility model is described in detail in conjunction with the accompanying drawings.

[0022] Combination Figure 1 and Figure 2 A filtering structure for producing furosemide oral solution includes a stirring barrel 1, a stirring mechanism 2 is arranged inside the stirring barrel 1, a filter box 4 is fixedly connected to the bottom of the stirring barrel 1, a bracket 5 for maintaining the stability of the equipment is fixedly connected to the bottom of the filter box 4, and a diversion component 6 is arranged inside the filter box 4.

[0023] The utility model is further described below in conjunction with embodiments.

[0024] Embodiment 1:

[0025] Combination Figure 2 and Figure 3 The shunt assembly 6 includes an expanded tube 61 fixedly connected to the inner wall of the filter box 4, a conduit 62 is fixedly connected to the bottom of the expanded tube 61, a horizontal long tube 69 is fixedly connected to the bottom of the conduit 62, three groups of shunt tubes 63 are fixedly connected on both sides of the horizontal long tube 69, and the bottom of the shunt tube 63 is fixedly connected to a first branch tube 64, a second branch tube 65, a third branch tube 66 and a fourth branch tube 67 with openings of increasing sizes in sequence, and the first branch tube 64, the second branch tube 65, and the third branch tube 66 are fixedly connected on the inner walls with flow-blocking protrusions 68 for slowing down the flow of water. The shunt tubes 63 are symmetrically arranged in pairs and arranged in sequence on both sides of the horizontal long tube 69. A filter membrane 42 for filtration is fixedly connected to the inner wall of the filter box 4, a connection port 41 is provided on the upper surface of the filter box 4, and a door for replacing the filter membrane 42 is provided on one side of the filter box 4.

[0026] Specifically, after the furosemide oral solution is dissolved, it enters the filter box 4, first enters the expanded tube 61, enters the horizontal long tube 69 from the expanded tube 61 through the conduit 62, and then flows into each branch tube 63 from the horizontal long tube 69. The first branch tube 64, the second branch tube 65, the third branch tube 66 and the fourth branch tube 67 fixedly connected to the bottom surface of the branch tube 63 have opening sizes that increase in sequence, and the distance between each branch tube is different. As the opening size continues to increase, the distance between the two branches continues to decrease, and the furosemide oral solution flows out from each branch tube in sequence, evenly flows through the filter membrane 42, and after a certain amount of furosemide oral solution flows in, a liquid seal is formed on the bottom of the branch tube, resulting in an internal and external pressure difference, thereby slowing down the flow rate, and finally achieving the purpose of controlling the filtration rate of the furosemide oral solution.

[0027] Embodiment 2:

[0028] Combination Figure 4 The stirring mechanism 2 includes a motor 21 fixedly connected to the upper surface of the stirring barrel 1, a rotating shaft 22 is fixedly connected to the output end of the motor 21, a scraper rod 26 is fixedly connected to the outer surface of the rotating shaft 22, a limiting wall 23 is fixedly connected to the inner wall of the stirring barrel 1, the scraper rod 26 is fitted with the limiting wall 23, a stirring rod 24 is also fixedly connected to the outer surface of the rotating shaft 22, a hole 25 for enhancing turbulence is provided on the surface of the stirring rod 24, a valve 27 is fixedly connected to the inner wall of the limiting wall 23, the opening direction of the valve 27 corresponds to the connecting port 41, a feed channel 3 is fixedly connected to the outside of the stirring barrel 1, a discharge channel 7 is fixedly connected to the bottom of the filter box 4, an inclined bottom surface 43 is arranged inside the filter box 4, and the inclined direction of the inclined bottom surface 43 corresponds to the opening direction of the discharge channel 7.

[0029] Specifically, the medicines to be mixed and dissolved are added from the feed channel 3, and the motor 21 is turned on. The motor 21 drives the rotating shaft 22 to rotate and drive the stirring rod 24. The holes 25 opened on the surface of the stirring rod 24 increase turbulence and enhance the dissolution effect. The scraping rod 26 scrapes the limiting wall 23. After the dissolution is completed, the valve 27 is opened, and the furosemide oral solution enters the filter box 4, thereby finally achieving the purpose of dissolving the furosemide oral solution.

[0030] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0031] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A filtering structure for producing furosemide oral solution, comprising a stirring barrel (1), a stirring mechanism (2) being arranged inside the stirring barrel (1), and a filtering box (4) being fixedly connected to the bottom of the stirring barrel (1), characterized in that: A flow diversion component (6) is arranged inside the filter box (4); The flow diversion assembly (6) comprises an expanded tube (61) fixedly connected to the inner wall of the filter box (4); a guide tube (62) is fixedly connected to the bottom of the expanded tube (61); a horizontal long tube (69) is fixedly connected to the bottom of the guide tube (62); three groups of diversion tubes (63) are fixedly connected to both sides of the horizontal long tube (69); a first branch tube (64), a second branch tube (65), a third branch tube (66) and a fourth branch tube (67) having openings of increasing sizes are fixedly connected to the bottom of the diversion tube (63); a flow blocking protrusion (68) for slowing down the flow of water is fixedly connected to the inner walls of the first branch tube (64), the second branch tube (65) and the third branch tube (66); and the diversion tubes (63) are symmetrically arranged in pairs and arranged in sequence on both sides of the horizontal long tube (69).

2. A filtration structure for producing furosemide oral solution according to claim 1, characterized in that: A filter membrane (42) for filtering is fixedly connected to the inner wall of the filter box (4), and a connection port (41) is provided on the upper surface of the filter box (4).

3. A filtration structure for producing furosemide oral solution according to claim 1, characterized in that: The stirring mechanism (2) comprises a motor (21) fixedly connected to the upper surface of the stirring barrel (1); the output end of the motor (21) is fixedly connected to a rotating shaft (22); the outer surface of the rotating shaft (22) is fixedly connected to a wall scraping rod (26); the inner wall of the stirring barrel (1) is fixedly connected to a limiting wall (23); the wall scraping rod (26) is in contact with the limiting wall (23); the outer surface of the rotating shaft (22) is also fixedly connected to a stirring rod (24); the inner wall of the limiting wall (23) is fixedly connected to a valve (27); the opening direction of the valve (27) corresponds to the connection port (41).

4. A filtration structure for producing furosemide oral solution according to claim 3, characterized in that: The surface of the stirring rod (24) is provided with holes (25) for enhancing turbulence.

5. A filtration structure for producing furosemide oral solution according to claim 4, characterized in that: The outside of the mixing barrel (1) is fixedly connected to a material inlet channel (3), and the bottom of the filter box (4) is fixedly connected to a material outlet channel (7).

6. A filtration structure for producing furosemide oral solution according to claim 3, characterized in that: An inclined bottom surface (43) is provided inside the filter box (4), and the inclination direction of the inclined bottom surface (43) corresponds to the opening direction of the discharge channel (7).

7. A filtration structure for producing furosemide oral solution according to claim 1, characterized in that: A bracket (5) for maintaining the stability of the device is fixedly connected to the bottom of the filter box (4).